Dbfetch
LOCUS NM_206295 5584 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster Puratrophin-1-like (Pura), transcript variant B, mRNA. ACCESSION NM_206295 VERSION NM_206295.3 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 5584) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 5584) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 5584) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 5584) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 5584) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 5584) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 5584) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 5584) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 5584) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 5584) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 5584) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 5584) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 5584) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 5584) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 5584) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (10-NOV-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 5584) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 5584) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 5584) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 5584) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 5584) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 5584) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 22 (bases 1 to 5584) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 5584) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 24 (bases 1 to 5584) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 25 (bases 1 to 5584) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jan 16, 2013 this sequence version replaced NM_206295.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..5584 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="3L" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..5584 /gene="Pura" /locus_tag="Dmel_CG33275" /gene_synonym="CG33167; CG33275; CG7511; CG7513; CG7515; CG7520; Dmel\CG33275" /note="Puratrophin-1-like" /map="66A6-66A8" /db_xref="FLYBASE:FBgn0035802" /db_xref="GeneID:2768948" CDS 762..5048 /gene="Pura" /locus_tag="Dmel_CG33275" /gene_synonym="CG33167; CG33275; CG7511; CG7513; CG7515; CG7520; Dmel\CG33275" /note="CG33275 gene product from transcript CG33275-RB; CG33275-PB; Pura-PB" /codon_start=1 /product="Puratrophin-1-like, isoform B" /protein_id="NP_996017.2" /db_xref="FLYBASE:FBpp0088790" /db_xref="GeneID:2768948" /db_xref="FLYBASE:FBgn0035802" /translation="MSTAAAALMASDCGELPQLLQNLLVSVERSIERVSLNELQMPMH HDRGEDSLDEANNNGCNNNLLGSPKCALRRSDLITKNKLFNSRYMLRRLTNRQDSMNS TSSGNSNVSDRSSSSSSSSSSSAGEELLTSHSEAKMRSNSVGNEASGASTSPALPLYC LGNSFPHIDSDEEASDSIGPGKHHSLETCETELLPSSSIAELPEKLLTSGVYLPGTRT LQGDPLVTVDAACVASAGINCYEMATLLLYYSTIPERSSCPFTTPATPGTTATINGHK STEQQQQQQQQQQQQKQQPAQQTFTILIAIEKSQHLCVIDLICQSLRLLAKQIGNCEI LAVCPDSSLLQLCNGQQQQKLQQQQQQNNNSDHPEPSSPSPVDLVKFISVDQVTTSVA PSQLPAGLLPSVPALSTLPGISQRHHDATKWREFFAQLEAFQRQCSTAGGRLVSALSE IRAADLQGLPTRRQLYGQHRALSRALMDSQLHSLRKMGAGQLARLQDLARAITSAPGS PRMTSQPQSSSSSSSGAFLNVDAACKLRKVTLLFNEVDRAAQRLEQLTEQRRERLRQL TRQRALEDEISEVTSWMGSDGAENLQKFSQLHWDNESQLRTQEQEFEKYYFIAMKHLA KGRDLHAAALKVSVLSESANNLKSALDQFAQKLELAHERYDAAGRLLHLLTQHQRENA AREELQRLAEQLGATSLLEKHWPVMRKTHTLPVASSTPAAAAGKRVSYRCSSASRSSF EGGPSSSNCSCWRESRNLEDMDQMEEEEEEQDHDCDGGDGEEQQSKIADSGLGVCDNC ERNPKLARICSCQSLNEKSHDELLEDECFDRPSKRYMDIMHSPMEANAHLQCHGSSLE LPKLEELSCLDPKIQKTLLLIMREMIGTERDYVRSLYYVIENYIDELLREDIPQPLRG QRNVIFGNIEKIFEFHNSHFLGELERYERNPLKVGAAFLEMESKFYLYALYNKNKPKS DTLLSEYGSSFFKPKQMQLQDKLDLASYLLKPVQRMGKYALLLQQLVKACKGVEGAAL QEIAADVEELQRAEEMVKFQLRHGNDLLAMDSLRDCDVNVKEQGRLLRQNEFLVWQGR GGKKTLRQVFLFEELVLFSKARRFPDHKNLDIYIYKNSIKTSDIGLTAHTGDSATKFE IWFRKRKPDDTWMLQCMSEDIKNAWTEEISKLLWKQAKRNREVRLAEMSSMGIGSKPC LDIRPSNNQISDRSIPLAQLNKTPKLRHSEPGKGSMRRPNSLISESSLSSGTSTTSGS SISGGSSSGHNDGGGRHSLHFGKLPGAHSASSTNCSATLELINETQALKLAKSPSGGG IKGADTAADGGNTSGNGNGNGNAFRSSKRNHKRSTTIVSQLSMESGIVSDMCVTPDQE QSAAESSRSSWSTSTTGASGASTTSASTVILRRYRSYAHAAESASPESGK" ORIGIN 1 aagtcagttg aacatttgaa ctcgcgacgc gcagtcttgt gagcggcaaa aagcgactga 61 caagccctga aaaagaaaag cgactcgaag acgaatgtat agagtagtaa acagaagtga 121 ccaagtgcaa cgtgccactg ccaactaaat acgtaaattc gtagtttcag agtatcgcat 181 cttttcgcca tttgggagct aacagagtgc gccgaaagaa atgtgcaaag tatcgttgaa 241 ttaacatgca aataaattga aatcgcgaca gagtgatgcc cgaatagtgc ctgcaaatac 301 gttataaaag tgccttaatg tgtgatcttt ttacaatctg caagaaataa tcgtaaaagt 361 gcgaatcagc ttcgtatagt ataaatatat actcctttcc caagtgccac atatatctgc 421 tatcagccta gaagttaacg ctttaaagcc gtcacatcag cgtaaatcag aggatttcct 481 cgccgaatag ttttgagtcc tggttatggc atcccggctg gcctttggca acatccaatg 541 gagcactggt cttgcagctg agcgacgctg agatcgcgca cgcacttcgt ccgtcggagc 601 tgtatctttg catcaaattg gaatctacag aaagcgacgc ggattgcaaa ccgcggctct 661 atgctgtttg gcgctcgtcc cgcaaggagg agagcgtcca gagccactgc atcgaccacg 721 agaatcccgg cgagttgccc ctgagcgtgc tccagctgga aatgtccacg gcagcggcgg 781 cactgatggc atccgattgc ggtgaactgc cgcaactgct gcagaatctg ctggtgagcg 841 tggagcgcag catcgagcgc gtttcgctca acgagttgca aatgccgatg catcatgacc 901 gcggggagga ctctctggat gaggccaaca ataatggatg caacaataac ctgttgggat 961 caccaaagtg cgcgttgcga cgcagcgatt tgattaccaa aaacaagctg ttcaacagcc 1021 gttacatgct taggcgtctg accaatcgcc aggatagcat gaactccacc tcgtcgggta 1081 acagtaatgt gagcgacagg agcagcagct ccagctccag ctcaagttcc agtgccggcg 1141 aggagctcct gaccagccac tcggaggcca aaatgaggag caacagcgtt ggtaatgagg 1201 caagtggtgc ctccacctcg ccggcattgc cactctattg tctgggcaac tcgtttccgc 1261 acatcgacag cgatgaggag gctagcgata gcatcggacc ggggaaacac cacagtctag 1321 agacctgcga gacagagcta ctgccgtcca gctcaattgc cgagctgcct gagaaactgc 1381 tgaccagtgg cgtctattta ccaggcacac gcaccctcca aggcgaccca cttgtgactg 1441 tggacgcggc ttgtgtggcg tccgccggca tcaattgcta tgaaatggcc acgctgctcc 1501 tctactacag cacaattccc gagcgcagct cctgcccctt caccaccccg gcaacacccg 1561 gaacgacagc tacaatcaat ggccataaaa gcactgagca gcagcagcag cagcaacagc 1621 agcagcaaca gcagaaacaa caacccgccc aacagacatt taccatttta attgccatcg 1681 agaagtctca acatttatgc gtaatcgact taatttgcca aagtctcaga ctcttggcca 1741 agcaaattgg caattgtgaa attttggccg tttgtcccga ttcgagtttg ctgcaattgt 1801 gcaatgggca gcagcaacag aagctgcagc agcagcagca gcagaacaat aacagtgatc 1861 acccggagcc ttcgtcgccg tcgccagtgg atttggttaa attcattagc gtggaccaag 1921 tcacgacaag tgttgcgcca tcgcagctgc ccgctggatt gctgccctcc gttcccgcgc 1981 tgtccacgct gcccgggatt agccagcgtc atcacgatgc caccaagtgg cgggagtttt 2041 tcgcccaact ggaggccttc caacgccaat gctcgacggc cggcggtcgt ttggtgagcg 2101 ccctcagcga aatacgcgcc gccgatcttc agggtttgcc cacgcgccgc caactttatg 2161 gccagcatcg cgccctcagt cgtgcgctga tggattcgca gctacacagt ctgcgcaaga 2221 tgggtgctgg ccagttggcc aggctgcagg atttggccag ggccatcacc tctgctcccg 2281 gctcgccgcg catgacgtca cagccgcaat catcctcatc ttcctcttcg ggggcattcc 2341 tgaacgtaga tgccgcctgc aagctgcgca aggtgacgct cctcttcaac gaggtggatc 2401 gggcggccca acgcctggaa cagctgactg agcagcgcag ggagcgattg aggcaactga 2461 cccggcaacg ggccctcgag gatgagatca gtgaggtcac ctcatggatg ggcagcgatg 2521 gagcagagaa tttgcaaaag ttttctcagc tgcactggga caacgagtcg cagttgagga 2581 ctcaggaaca ggagtttgaa aagtactact tcatagccat gaaacacttg gccaaaggac 2641 gcgacttgca tgctgctgcc cttaaagttt ctgtcctaag tgaaagcgcc aataatctaa 2701 agtccgccct ggatcaattc gcccagaaac tggagctggc ccacgaacgc tatgatgctg 2761 ccgggcgtct gctgcacttg ctcacccagc atcagcggga aaacgccgcc agggaggaac 2821 tgcagcgttt ggctgagcaa ctgggcgcca cctcgctgct ggagaagcac tggccggtga 2881 tgcggaagac ccatacgttg ccagtggcca gtagcacacc ggctgcagct gctggaaaac 2941 gggttagcta tcgctgcagc tcggccagta ggagttcctt tgagggaggt ccatcgagca 3001 gcaattgcag ttgctggcgg gaaagtcgca acctggagga catggatcaa atggaagagg 3061 aggaagagga gcaggatcac gattgcgacg gtggtgatgg agaggaacaa cagtccaaga 3121 tcgccgattc tggtttgggc gtttgcgaca attgcgaacg taatcccaag ctggccagga 3181 tttgctcctg ccaaagcctt aacgaaaaga gtcacgatga gctgctcgag gacgagtgct 3241 tcgatcgacc ctctaagaga tacatggaca tcatgcactc gcccatggag gcgaatgccc 3301 atctgcagtg ccatggctcc agtctagagc tgcccaagct ggaggagctc agctgcctgg 3361 atcccaagat acaaaaaacg cttctattga tcatgcgtga gatgattggt accgaacgcg 3421 actatgtccg ctccctgtac tacgtgatcg agaactatat agatgaactg cttcgcgagg 3481 atatccctca gccactgagg ggccagagaa atgtgatctt cggtaatatc gagaagatct 3541 tcgaattcca taactcgcac ttcctgggcg aactggaacg ctacgagagg aatccattaa 3601 aagtgggagc tgcctttctg gagatggagt ccaaattcta cctatatgcg ctttacaaca 3661 agaataaacc caaaagcgat actttactaa gcgaatatgg tagctcattt ttcaagccca 3721 agcaaatgca gcttcaggat aagctagatc tagcctctta cctcctgaaa cccgtgcaga 3781 gaatgggaaa atatgcattg ctcctgcagc agttggtcaa agcctgcaaa ggtgtggaag 3841 gagcagctct acaggaaatc gcagcggatg tagaagagct gcagcgagca gaagaaatgg 3901 tcaagtttca gctacgccat ggaaatgatc tgctggccat ggactccttg cgcgattgcg 3961 atgtgaatgt caaggagcag ggacgactac tgcgccaaaa tgaattcctc gtttggcaag 4021 gacgcggtgg caagaaaact ctgcgacagg tgtttctctt cgaagaactg gtgctcttca 4081 gcaaagctcg tcgctttccc gatcataaga atctggatat ctacatctac aagaacagca 4141 ttaaaacttc agatatcggc ctcacagcgc acacaggtga ttcggctacc aagttcgaga 4201 tttggttccg gaaacgaaag cccgatgata cgtggatgct acagtgcatg tcggaggaca 4261 ttaagaacgc ctggaccgag gagatctcca aactgctctg gaagcaggcg aaacgaaacc 4321 gagaagttcg cctggcggag atgtcctcaa tgggcattgg cagcaagccc tgtctagata 4381 ttcgacccag caacaaccag atcagcgatc gctcgattcc cttggcacag ctaaacaaga 4441 ctcccaaact gcgacactct gagcctggaa agggcagcat gcggcgtccc aattcactga 4501 tatcagagag ctccttgtcc agcggcacca gcactaccag tggctcctcc atcagcggtg 4561 gctcctcctc gggtcacaat gatggcggtg gcaggcacag cctgcacttt ggcaagctgc 4621 ctggagcaca cagcgcaagt tccaccaact gcagtgccac tttggagctg atcaacgaaa 4681 ctcaggccct gaagttggcc aaatccccga gtggaggtgg aatcaagggg gcggatacgg 4741 ccgccgacgg aggcaacact tccggaaacg gaaatggcaa cggaaacgca ttcaggagca 4801 gcaaacgaaa ccacaaacga tcgacgacca ttgtcagcca actgtccatg gagagcggca 4861 ttgtctcgga catgtgcgtt accccggatc aggaacaatc ggcggcggag agcagccgaa 4921 gcagttggtc cacatcaacg actggagcat ccggagcttc aacgacgagt gcatccacgg 4981 taatcctgcg gcgatatcga tcctacgccc acgcagcgga gtccgccagt ccggaaagcg 5041 gcaaatagag gagctcctgg agcatcgcat ctagatatag tataaatccc cattaatagc 5101 tttagcagaa cggtttcatc ggatcccatg tagtatcatc gtattacgtt cgatcgctaa 5161 ttttatttca ttatttttgt tatttattat ttattacatt tttagttttc gttaatttgt 5221 catagtcgct gcttttcgtt ttgccttgtt tatcggaaaa atcagtcgaa attattgaat 5281 tcagcgtgtc aatgtcgaag caagtttcat acatatctag ttcttagtcc acacaatcga 5341 acgatccgca ccacacacac acagaaatcg atgggagcca tgagcagcac ccgaaaaagg 5401 ggcgtggccg atgcccaaca tatctgaatc gaacttcatt acgtacagtt agttgatatg 5461 taacctaagt gcctatagtt aaaataatcg taaacgaaca ttaaaaaaat atatctatac 5521 ttcataataa ctcgataaat aattttaagc gaaaatttaa attcaataaa tgttgcttca 5581 atgt //