Dbfetch
LOCUS NM_206278 10858 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster still life (sif), transcript variant C, mRNA. ACCESSION NM_206278 VERSION NM_206278.2 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 10858) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 10858) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 10858) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 10858) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 10858) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 10858) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 10858) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 10858) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 10858) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 10858) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 10858) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 10858) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 10858) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 10858) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 10858) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (10-NOV-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 10858) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 10858) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 10858) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 10858) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 10858) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 10858) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 22 (bases 1 to 10858) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 10858) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 24 (bases 1 to 10858) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 25 (bases 1 to 10858) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jul 15, 2014 this sequence version replaced NM_206278.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..10858 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="3L" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..10858 /gene="sif" /locus_tag="Dmel_CG34418" /old_locus_tag="CG32414" /old_locus_tag="CG5406" /old_locus_tag="Dmel_CG32414" /old_locus_tag="Dmel_CG5406" /gene_synonym="CG32414; CG34418; CG5256; CG5406; Dmel\CG34418; Dm_3L:26493; lincRNA.447; RhoGEF; Sif; SIF; slf; Stilllife" /exception="dicistronic gene" /note="still life" /map="64E1-64E5" /db_xref="FLYBASE:FBgn0085447" /db_xref="GeneID:43892" CDS 1627..7812 /gene="sif" /locus_tag="Dmel_CG34418" /old_locus_tag="CG32414" /old_locus_tag="CG5406" /old_locus_tag="Dmel_CG32414" /old_locus_tag="Dmel_CG5406" /gene_synonym="CG32414; CG34418; CG5256; CG5406; Dmel\CG34418; Dm_3L:26493; lincRNA.447; RhoGEF; Sif; SIF; slf; Stilllife" /note="CG34418 gene product from transcript CG34418-RC; CG34418-PC; sif-PC; still life; still life type 1; still life type 2; still-life" /codon_start=1 /product="still life, isoform C" /protein_id="NP_996000.1" /db_xref="FLYBASE:FBpp0111622" /db_xref="GeneID:43892" /db_xref="FLYBASE:FBgn0085447" /translation="MEQKCIRRKGSVRLTEPTGHAHVRIEQRPQLPPRRQKSAEEVAT MPKSALRQPPEQLEWFDRRAQQRHSARSAEGGQVREETMEWLKLQKTASPIQPVRTSS GPSEITVLKDELPDWLLDHLPRKKERERDRLPSDADKAVGSAYAKALADLLKKPLSRQ GSGPCEFSLLKTDIVEWLTKMQSSSGTDRGKSRRSHHRRNGSGGDAQPRSNSQEDAQD QSKTSHRKRHSLGHSGAVSEEEQQQLTADWIAYPLHKLQSLGKQPPPAQPPERMSIPS GYAVPSALSHTPLCQRREERSRERRLRHSASEVVGSGGAGAASTSNTAHLERLYAKPH KERYQYVPKTKESSGRKERSRRHQTQRSATVSDMSAQRSGGHKRKSSSAERAPRSPSP GPCTDPDCPLLPICTDPHCRYQECQARQCITSSVSSVNLARHQQLAQVQLHAVPAHLV GAMGSDVPTTPSTTATPPPPTGGGTMGVGATGAGAGATSERRLVICHDCRSCAPLLSC RNRKCLNAAKCNSLPRCAADFNRLRTQLSQPPTTLDDIEPAPLDDLEMQPLPSPPHPH PHHHYRSNSQPNTLQRGDSASSAGMGAGVGGAGHGGLGGPGSGLAWLEPTTTLVQPLP AYVHHSNGKLMKSASAASLNSRRRRHKTVHFGENLLREVCQNRKLIKTEAQVPSGSAP MKANIQMLYNFVEGVLSAWVDDDEDQVRSGAESEPEHGVVPMQPIHRCNRLRYQCIRR VVEEAADLQGTLKLGNSRYRHRHWRSTAKQCNEMFLRKISDDDRMSLTTAVSDEDDGE SVMASPYKAKATGTAASSFNCTGAVRKAGFLSVKKWLLRKKHQIELARKRGWKGYWVC LKGTTLLFYPCDSREGRSVEAAPKHLIIVDGAIMQPIPEHPKRDYIFCLSTAFGDAYL FQAPCQVELENWVNSIHSACAAAFARHRGKTGTLHLLQEEIFRLEKAIESDHKLKHMA ELQQSVVTDQETRHQIQTQILQWEENLERLHCEQFRLRCYMASLQSGELPNPKSLLTH VSRPTKNTLNKLGVFTVSSFHAFICARSPSLLNNLLAGRGATKRRPPMLSRSNSGSSR RSMQMNSRDEPEKTFKVAMPDNAYSTVYLRDAMSVEEFLASACARRNLNPMEHFVRVK KRRDMEDHNYFVPHRNDLIENYLHNHEFVEVCMKILYQVELQRTTLEQMWGFSVEAEL IENAERQDELCCYVSRVEDKSVAMHNGIIKGDEIMVINGAIVSDLDMMYLESVLQEEQ SLSMMMRSSRTEPPDLVGIMRVTDDMIDSLVCPPPPTDPPVMSEEMITGLIVPAPGWN GTSKDLYSPEAESSPATSFVDPAAMAAQLAVGGVGGVVVGGLGVAKPTSRTSSFEIEN LLKTAEQVTGFCRSPQETRKSSPTGSVTSSVSTTALTPSRQLTDAEKLRKVVMELVDT ERTYVKHLNNLLEHYLEPMKRETFLSNAEINALFGNIHEIVTFQRQFLQNLEESLDLE PDFNKFEHCGQFRNVLFAIGSAFLYYVNHFKLYSSFCASHSKAQKVLHPNEGNHALQE FLAARNPKQQHSSTLESYLIKPIQRILKYPLLLQQMRNLTDTRADEHVHLCEALKGME KVAEHINEMQRIHEEYGAIFDHLFRQHQKSCKQPIDLSPGDLLYYGGVEWLNISDFLG KIKKGLELHAMCFVFKSAVVFLCKERLRQKKKLMGVSSKNATNEVEIIRYQVLIPVTE VQVRASSAKDMDSHFLWELIHLRSQLQRRSEKVYVLSNSTADFRNAFLKTIRQIIRES VRNMSIPMKNFGGSSGSVSGHSSQGMGSMGYPGNSQTLERPKQQITIVHGSHTLGKPK KKSGSQRHSAGNIDYDNLSGSQEADDLPPSVGVVHYASGHTHGQQMQPAGFRGRSKTV GDVTEITCSSPEPHQQQQQQQQQQQQLMQQGHAHAHPHPHPHPREPPPPPIRQPHLHH HSSDIERIDPGTKSEGEEDSQQGTIRPKATLGRTPNHLTLSTTSTLSVGSTGSQARLI QSSHPPASYQPVLMKDLGSPVWKPRDMINLGTDPQSTTRKDDVKN" ORIGIN 1 agtcagaacg ggaacgtcgt cgcgagctgt gcttggtagc gctctctggc agctgtgtgt 61 aacgccattt tgtaacgcga acgcaataga ccagtctatg gacttgtgtc ctgtgtcggt 121 ccacaagtcc tatcgtcctt cgccaaacgt cgtcgtcgct aaacgctaaa ataaatcata 181 aattccagcg tgtgtgtgcc gccgccaatc gtatcgtatc gtatcggtat tgaatcgaat 241 cgcatcgcat cgaatcgcat aaaatcaaat caaaacgggt caggaaagct gggaaaagtc 301 cgagaaaagt gcgtcagcag ccgttgaagc aggcacatcg catcatcagc gctgaaaata 361 aatgtgtgcg acgcgtgtga gataaattgg caaagcaaca gagccaacaa cagcaaaacc 421 gaaaacgaaa acgaaaaaca acccctgctg ccgatgtaat aaatgactgt gccgcaaaat 481 gagattttag tttaattaat caaatgaata ataatcagca ctaaatagtt gaggccagtg 541 gaaagtgaaa aagtggcaag tgcaaaagtg cacacacaca caaatggcgg actagcgccg 601 gatgtacggg atactgagga caggacatcg gcatcgtcaa ggacgaaaag gacctcgccc 661 ccgttgctgc cgctgtgatt cagattcatt ctggccgccc aacaaggcaa caacaacagc 721 gagcgcggcg atcacagcgg cgatcacagc ggcaatagtg gtgcgatcgg tggtgcaccg 781 ccatctctta gtggtggtgt tagtgttggt gttgcggctg caggcgatcc agcgggtccg 841 ggaggcggcg gaggaggtgg cggcggtggt ggtggaggtg gcggtgctgc aggaggaacc 901 ggaaacggaa ccggaggcgg aagcggaagc ggaaacggaa gtgctggcgg ggcggactgc 961 agcagcgacg gcgatcccaa gaagaccttc tcgctgcact gctgttgcgt gatcgtcgac 1021 atcacaccag tggcgcatcc aggaggacgc ctgacatcgg caacaacggc ctcgggaagg 1081 gatgcgggtg gagccgccgc tggcggaggt ggtggttccg gtggtggcgg tggcttgggc 1141 ctcggcctcg gcgagaatgt ctcccagttg gccagccaac tctttcgctt tggcagcaaa 1201 aagcgtccag gcgtttgcat ctgcaatgcc cagtgccggc tgcaatcgct gggtgagacc 1261 aaaggcagcc tgggagccac cacacttaag acccatcatg gcagcctgga cagattgctg 1321 caaaagggag acggaattgg tacagcaacc agtggtgagc gctcgataag ctgggtggtg 1381 gatggtggtg gggcgggctc tggtgccctg ctcaatgcct cctccgacga aagtgatgac 1441 aagaagaaga aactggacga gggcaaccag ctgccgccac cgccacgccc accctcgcgg 1501 tcacatgcca agcccacggc gaaggaggaa ttcgatcggg gtgtcgaagt ggagaagttc 1561 tatcaccaga tcaacggcga catcttcgaa atcactcgac gggtgagagc tcgcgatgag 1621 gagacaatgg aacagaaatg catcaggcgg aagggatcgg tgaggctaac ggaacccacg 1681 ggtcacgcac acgtgcgaat tgagcagaga cctcagttgc caccgagacg gcagaaaagt 1741 gccgaggaag tggccaccat gccaaagagt gccctgcgcc aaccgcccga gcaactggag 1801 tggttcgatc gccgggctca acagcgtcac tccgcccgat ccgctgaagg tggccaggtg 1861 cgggaggaga ctatggagtg gctgaagctc caaaaaactg ccagtcccat ccagccagtg 1921 cgcacctcct cgggtcccag tgagatcaca gtcctaaagg acgaactgcc cgactggctg 1981 ctcgatcatc tgccgcgtaa gaaggagcga gaacgcgatc gattgccttc ggatgcggac 2041 aaggctgtgg gttctgcgta tgccaaggcc ttggcggatc ttctcaagaa accgctgtcc 2101 cgacaaggtt ccggaccctg tgagttctcg ctgctgaaaa ctgatattgt ggagtggctc 2161 accaagatgc agagcagcag tggaacggat aggggcaagt cccgtcggtc gcatcatcgc 2221 cggaatggca gtggtggcga tgcccagccc cgttccaatt cccaggaaga tgcccaagat 2281 cagtcgaaga ccagccatcg gaagagacac tccctgggac acagtggagc agtcagcgaa 2341 gaggaacagc aacagctcac tgccgattgg atagcctatc ctctccacaa gctgcaatcc 2401 ctcggaaagc aacctcctcc agctcaacca ccggagagaa tgagcattcc cagtggctat 2461 gcggtgccca gtgccctttc acacactccc ctatgccagc ggagggagga gcgttcacgg 2521 gagagaagac tgcggcactc ggccagcgaa gtggtgggga gtggtggggc aggagcggca 2581 tccacatcaa acaccgccca tctggaacga ctgtatgcca agccgcacaa agaacgctat 2641 caatatgtac cgaaaaccaa ggagtctagt ggtcggaagg agcgttcccg tcgccatcag 2701 acccaaaggt ccgccacggt ctccgatatg tccgcccagc gttccggtgg ccacaagcgt 2761 aagtcttcga gtgcggagag ggctcctcgt tcaccatccc cgggaccctg tacggatccc 2821 gattgtccac tactgcccat ctgtacggat ccgcactgcc ggtaccagga gtgccaggcg 2881 aggcagtgca tcacgtcgtc ggtgagttcg gtaaatctgg ccaggcatca gcaactggcg 2941 caggtgcaac tgcatgcagt tccagctcat ctggttggag ccatgggctc cgatgtgccg 3001 acgacaccat ccacaacggc aacgcctccg ccgccaacag gaggtggaac tatgggagtg 3061 ggagcaaccg gagcaggagc tggagcgacg agcgaacgcc gtctggtcat ctgccacgat 3121 tgtcgatcct gtgccccgct gctcagctgc cggaatcgca aatgcctcaa tgccgccaag 3181 tgcaactcac tgcctcgctg tgccgccgac ttcaatcgcc tgcgcaccca gctgtcccag 3241 ccgcccacca cattggatga cattgagccg gcgccactgg acgacctgga gatgcagcca 3301 ctgccctcgc caccgcatcc acatccgcac catcactatc gcagcaattc acaaccaaac 3361 accctccaga gaggagactc cgccagttcc gcaggaatgg gtgcaggagt cggaggtgct 3421 ggacatggtg gattaggagg accgggatcg ggcctcgctt ggctggagcc aacaaccacg 3481 ctagtgcaac cactgcccgc ctatgtgcac cactccaatg gcaagctgat gaaatccgcc 3541 tcggctgcct cactgaattc ccgtcgacgg cgtcacaaaa ccgtgcactt tggcgagaat 3601 cttctgcggg aggtgtgcca aaaccggaag ctcatcaaga cggaggccca agtgccctcc 3661 ggttcggcgc ccatgaaggc caacatccag atgctgtaca acttcgtgga gggcgtgttg 3721 agcgcctggg tggacgacga cgaggatcag gtgcgctctg gtgcggaatc ggagccggag 3781 cacggtgtgg tgcccatgca gccgatccac agatgcaacc gcctgcgtta ccagtgcatc 3841 cggcgcgttg ttgaggaggc tgccgatctc cagggcaccc tgaaactggg caactcccgc 3901 tatcgccatc gccattggcg cagcaccgcc aagcagtgca acgaaatgtt ccttcgcaag 3961 atttcggacg atgatcgaat gagcctaact accgccgttt cggatgaaga tgatggggaa 4021 agtgtcatgg cgtcaccata taaagcaaag gcaactggca ccgctgcatc ctccttcaat 4081 tgcacgggag ctgttcgcaa agccggcttc ctatcggtaa agaaatggtt actacgcaag 4141 aagcaccaga tcgagctggc aagaaagcgg ggctggaagg gctactgggt gtgcctgaag 4201 ggcaccacgc tgctcttcta tccgtgcgat tcccgggagg gccggagtgt ggaggcggcg 4261 cccaagcact tgattatcgt ggatggtgca attatgcaac cgataccgga gcatcccaag 4321 cgcgactaca tcttctgtct gagtacggcg ttcggcgatg cctatctctt ccaggcgccc 4381 tgtcaggttg agctggagaa ctgggtgaat agcatacaca gcgcctgtgc cgccgccttt 4441 gccaggcatc gcggaaaaac tggaacgcta cacctgctcc aggaggagat cttccggctg 4501 gagaaggcca ttgagtcgga tcacaagctg aagcacatgg ccgaactgca gcaatcagtt 4561 gtcaccgatc aggagacgcg tcatcagatc cagacgcaga tactgcagtg ggaggagaat 4621 ctggagcggc tccactgcga gcagttccgg ctgcgctgct acatggcctc gctgcaaagt 4681 ggcgagctgc ccaatccgaa gtcgctgctg acacacgttt cgcggcccac gaagaacacg 4741 ctgaacaagc tgggcgtgtt cacggtctcc tccttccacg ccttcatctg cgcccgctcg 4801 ccctcgctgc tcaacaacct gctcgccgga cgcggggcca ccaagcggcg accgccgatg 4861 ctgtcgcggt ccaacagcgg ttccagccgt cgctccatgc agatgaattc acgtgacgaa 4921 ccggaaaaaa ctttcaaagt tgcaatgccc gacaatgctt actcgacagt ttatctacgt 4981 gatgccatgt ctgtggagga attcctcgcc agcgcctgcg cccgtcgcaa cctcaatccc 5041 atggagcact ttgtgcgcgt caagaagcga cgtgacatgg aggatcacaa ttactttgtg 5101 ccgcatcgca acgatctgat tgaaaattat ctacataatc acgagttcgt ggaggtctgc 5161 atgaagatcc tgtaccaggt ggagctgcag cgcacgactc tggagcagat gtggggcttc 5221 tccgtggagg ctgagctgat cgagaatgcg gaacggcagg acgaactgtg ctgctacgtg 5281 agtcgcgtgg aggacaagag tgtggccatg cacaatggca ttatcaaagg agacgaaata 5341 atggtcatca atggcgcaat tgtgtccgat ctagatatga tgtacttgga gagcgtcctg 5401 caggaggaac aatcgctcag catgatgatg cggtcctcgc gcacggagcc accagatcta 5461 gtggggatca tgagggttac ggacgatatg attgactcgc tggtttgtcc gccgccgccc 5521 acagatccgc cggtgatgag cgaggagatg ataactggac tgattgttcc ggcccccggt 5581 tggaatggca ctagcaagga tttgtactcg ccggaggctg aaagctcgcc ggccacctcc 5641 tttgtggatc ctgccgcaat ggccgcccag ctggcggtgg gcggcgtggg aggcgtggtc 5701 gtgggcggac tgggcgtggc caagccaacg tcgcgtacga gcagctttga gattgagaat 5761 ctgctaaaga ccgcggagca agttaccgga ttttgtcgtt caccccagga aacgcggaaa 5821 tcgagcccaa ccggctcggt cacctcatcg gtgtcgacca cggcattaac accatcacgg 5881 cagctgaccg atgcggagaa gctgcgcaaa gtcgtcatgg agctggtgga cacggaacgc 5941 acctatgtga agcacctaaa caacctgctg gagcactatc tggagccaat gaaacgcgag 6001 acattcctgt ccaatgccga gatcaacgct ctgttcggca acatacacga gatcgtcaca 6061 ttccagcgcc aattcctgca gaatctggag gagtccttgg acctggagcc ggatttcaac 6121 aagttcgagc actgcggcca gttcagaaat gtgctctttg cgattggctc ggccttcctg 6181 tactacgtca atcacttcaa gctctactcc tcgttctgtg ccagtcacag caaggcgcag 6241 aaagtcctgc atccgaacga gggcaatcac gccctgcagg agttcctcgc agccaggaat 6301 cccaagcagc agcatagcag caccctggaa tcgtatctga tcaagcccat tcagcgcatc 6361 ctcaagtatc cactgctcct gcagcagatg cgcaacctca cagacacccg ggccgatgag 6421 catgtgcatc tttgtgaggc actcaagggc atggaaaagg tcgccgagca catcaacgag 6481 atgcaacgca tccacgagga gtacggtgcc atattcgatc acctgttccg gcagcaccag 6541 aagtcttgca aacaacccat tgatctaagt ccaggggatc tgctctacta tggcggagtg 6601 gaatggctca acatctcgga ctttctgggc aagatcaaga agggactgga actgcatgcc 6661 atgtgctttg tgtttaagtc ggcagtggtg ttcctgtgca aggagcgact gcgtcaaaag 6721 aagaagttga tgggcgtttc cagcaagaat gccaccaatg aggtcgagat cattcgctac 6781 caggtgctca tacccgtgac cgaggtgcaa gtccgcgcca gttcggccaa ggacatggac 6841 tcccacttcc tgtgggagct catccatctg cgttcccaat tgcaacgccg ctccgagaag 6901 gtctatgtgc tgtccaacag cactgccgac ttccgcaacg ccttcctgaa gaccattcgc 6961 cagattatcc gcgaaagcgt ccggaacatg tcaattccga tgaagaactt tggcggcagc 7021 tccggctccg tctccggcca ttcctcgcag ggcatgggca gcatgggcta tccgggcaac 7081 tctcagacgc ttgaacgtcc caagcagcag atcaccatcg ttcatggctc gcacactctg 7141 ggcaaaccga agaagaagtc cggctcgcag cgccactcgg ctggcaacat tgactacgac 7201 aatttgtcgg gcagccagga ggcggacgac ctgccaccca gtgtgggcgt ggtccactac 7261 gcctccggcc acacccacgg ccagcagatg cagccagctg gattccgcgg tcgcagcaag 7321 acggtgggcg atgttacaga aatcacctgc tcttccccag aacctcatca gcagcagcag 7381 cagcagcaac agcaacagca acagctgatg cagcagggac acgcccatgc ccacccacat 7441 ccccatccgc atccaaggga gccaccgccg cctccgatca ggcagccaca tctgcaccat 7501 cacagctcgg acatcgaaag gatcgatcct ggaacgaaat cggagggcga ggaggactcg 7561 cagcagggca caatcaggcc caaggccaca ctgggtcgaa cgcccaatca cctgacgttg 7621 agcaccacat cgacgctctc ggtgggcagc accggcagcc aggcgcgcct cattcaatcg 7681 tcgcatccac cggccagtta ccagccggtg ctgatgaagg acctagggtc cccggtgtgg 7741 aaaccacgag acatgataaa tttaggcaca gatccacagt caacaacccg caaagacgat 7801 gtgaaaaatt aaatcagaaa aagcaaagca aaacgtttag tatcaagcta agcaagcata 7861 agaactctta atccacaact tcaaatcctc tgttcgattt ctcaatttta cctaatcaag 7921 tgtaaggcaa cggcaacaga aacagctaaa agcaaagcaa agcaaaagca gaaagcagaa 7981 agcaaaagca gaatgcaaac agcagaagca agcagttcaa agttcaaagc aggcgaaccc 8041 aaaagcattt ttcaagctca attctgcgat atgaagatgc attgaatcac cggccatcat 8101 cggtgtttgg tgaatggatg tggttgtttt ttgaagaatg cttggcttcg gtttgctttc 8161 gctctttttt aatggataaa acatcgaaga gtttttgtca ttttttacgt ttgcgttttt 8221 aaacgggaga agcaccacga aagggatgtc acagatcctt tttagaaaga gagaacaaac 8281 aaaaaaaaaa cggaacaaaa cctaaagcat aaatgaaaac caaaagagaa gactttcatt 8341 tatattgatt gtatttaaag tgcaaaacat ataataaaag cataattaaa gcgaaggatt 8401 ttgagcaaat ttaatatgaa ctaagtgaac agatttaaca aaattaagaa atacgagaac 8461 aaattcaaat gcatttgtcg ctgaaaagac ttgaaagtaa atttcgattt aaatacatac 8521 atttattgag gacaagacga agaagcagct gtcaaagcga cgaggaggga aacccgtaaa 8581 caaattgcaa ccatagtatt taggcttaga gaatttaaat tataaaaaag aaaacaaacg 8641 aagaccccag agatttgcaa aaaaaaatat aagaaaaaag aatgaaacaa aagtcaaatg 8701 caaagtaagc aaaaccaaag ggttgaatga aaaacatttt agccaattaa gccacacaca 8761 cacacacaca aactgaagca aatcaacaca ctcataagcg taatgagaaa atttaaatga 8821 aaacagcaat gaaaatgttt agttcgtagg aagtacactg aaaaaataca taaagatacc 8881 atacaaaatc cacacataca cataaacgaa aaatagcaaa aatttagtca aaatgttaaa 8941 tggtaaacta aatgaaaccg aaataataat aacgaagcaa atgattccat gcaattaaat 9001 tgggctaaca gcctccacaa agaatccaat cagcaaatac aagcaaacaa aaattaactc 9061 aaagcaaact caacacgtta aagcgggcga acattaaatt aaactataaa actatgcaaa 9121 gaaaaccaaa taaatgaaag tacataagca taaaaaagca aaagaaaccc aaataaaaaa 9181 aaagacaaca ccttctagca gaattacaat aataattaag aacttcactt tgaacacttt 9241 gaaacaaaca cacgcgaatc gatatagtta aacaaaggaa gcctattccc agcccaacaa 9301 aaaaaaaaaa atcccataga caaaggcaca gttttcgaga actcgattaa aggatacttt 9361 tgattttcct acgtctcaat accctatggt tttcaatttt tgtaggacga atttttagcc 9421 agacgatgca aatatataat cgaatacaat gaaaaaattc taccagatga gaaataataa 9481 ttaattggtt gtgaatgcag cttggatgtt aattcgattc aggaacaatg aaatccccaa 9541 ttgctgaacg tttgtttatt ttactggccg cacacacagc agtgtgcgtg tgagtggcaa 9601 ttgtcttttt tttttcagtg tacttgcagt tgcattgctc acactcattc attttgtacg 9661 ccaccccccc ccctccaccc actctcagaa aaacgtcata aactcattga accatatagc 9721 aacaaatcga aacataatca aaacattttt taggtttcca atcaaattga attaaatata 9781 caaaaaataa actcgaatta aacaatgaga aaaactaaga aaaacgtaat aattgaaact 9841 acagaccata gacagctata tgatgtggag agtaaataga aattctaaat gtatacaaca 9901 gtctaatgat agatcttcat catcgcatca acgatgagga tgattatgaa gatgaaagct 9961 aatcaaacac gggacaaaac aaggagaaat ttaccaaata ccaaatcaca acattttaac 10021 ataattttta cagtttgtat aagttcgaca gaggcaacgt acataaataa taattataat 10081 gattaacaat aaaaaccaac agtcagttgg aagactttag cgaaatgaaa tagttaaatt 10141 atgaaactca tttgatggcg aatgaacgtg gcgtgaaact ttttgtacgc atttgactat 10201 ttttaaagca tttttattaa atatatatac atacatagtc actattatac gaatgtttga 10261 gaaccaaacg aatgtactca tttaattaag ttcacgtgca cacaatgcac tggaatctct 10321 tttaacaaat tgttatcgga tatttgattt gtttaagcgt attgttagtt atatgtacat 10381 gtatctctta tcacactttc ctttcgacaa gcgaacgagg cagcaggaaa aacgagggta 10441 acaattgcat attaaataca atttataagt cagccacaca acacacacac acacacacac 10501 acacacacac gaaaaccaaa ttcgaaacag aaatcaatag caaaatgcag caggattgga 10561 aacaaatgtt gccattttcg aatggacaac agcagacagc aacattgaaa ttcaattttt 10621 attgtaaacc taattagcag ctgcaaacaa gaagaacaaa aatatattac aacaaaaacg 10681 aacatgaaat ggatgttaat actttttgaa aaagagaata aaaaaaaaaa acaaatatgc 10741 aacagtaaag aaagtaaaaa gaaatacaca atgattatac aattgcaaat gcaacttaac 10801 actcaacata aggatagtga aaatgtgtga caaatgatta aattacgaaa tccttttg //