Dbfetch
LOCUS NM_205972 5437 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster Multidrug-Resistance like protein 1, transcript variant H (MRP), mRNA. ACCESSION NM_205972 VERSION NM_205972.2 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 5437) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 5437) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 5437) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 5437) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 5437) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 5437) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 5437) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 5437) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 5437) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 5437) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 5437) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 5437) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 5437) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 5437) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 5437) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (10-NOV-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 5437) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 5437) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 5437) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 5437) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 5437) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 5437) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 22 (bases 1 to 5437) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 5437) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 24 (bases 1 to 5437) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 25 (bases 1 to 5437) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jan 16, 2013 this sequence version replaced NM_205972.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..5437 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="2L" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..5437 /gene="MRP" /locus_tag="Dmel_CG6214" /gene_synonym="ABCC1; CG6214; DmCG6214; Dmel\CG6214; dmrp; dMRP; dMRP/CG6214; dMRP1; lincRNA.123; Mrp; Mrp1; MRP1" /note="Multidrug-Resistance like Protein 1" /map="33F3-33F5" /db_xref="FLYBASE:FBgn0032456" /db_xref="GeneID:34686" CDS 155..4801 /gene="MRP" /locus_tag="Dmel_CG6214" /gene_synonym="ABCC1; CG6214; DmCG6214; Dmel\CG6214; dmrp; dMRP; dMRP/CG6214; dMRP1; lincRNA.123; Mrp; Mrp1; MRP1" /EC_number="7.2.2.-" /note="CG6214 gene product from transcript CG6214-RH; CG6214-PH; MRP-PH; multidrug resistance-associated protein; multidrug resistance like protein; multidrug resistance-like protein; multidrug resistance-like protein 1; Multidrug-Resistance like protein 1; Multidrug-resistance protein" /codon_start=1 /product="Multidrug-Resistance like protein 1, isoform H" /protein_id="NP_995694.1" /db_xref="FLYBASE:FBpp0089063" /db_xref="GeneID:34686" /db_xref="FLYBASE:FBgn0032456" /translation="MADDTSSPMDRFCGSTFWNATETWYTNDPDFTPCFEQTALVWTP CAFYWAFVIFDFYYLKASLDRNIPWNKLNVSKALVNLGLLVITALDLIMALVKKGGDS ELPLYDLDVWGPIIKFATFLLLFIFIPLNRKYGVQTTGCQFIFWFLLTVLSIPRCRTE VRLDAERQKILNSQQPSEQDFSWEEYQFVSFFIFFTFTSIMLILNCFADGMPRQTKYQ RGENEIPELSASFLSRITYQWFDKMALKGYRNPLEEKDLWDLRPQDSCSEVMPIFAHH WNQNVRKNYKNKARVEPKAQFSNGNVTFENPHGEKNGRKKGMASIMPPIYKSFGGVFL FGALMKLFTDTLTFAQPQVLSLIISFVEAQDAEPEWKGILYAVLLFVLAAAQTFILGQ YFHRMFIVGLRIRTALINAIYRKALRISNSTKKESTVGEIVNLMAVDAQRFMELTTYL NMIWSAPLQIGLALYFLWQQLGPSVLAGLAVMIILIPVNGVIASRIKTYQIRQMKYKD ERVKLMNEVLSGIKVLKLYAWEPSFEKQVLDIRDKEIATLRSTAYLNAGTSFLWSCAP FLVSLVTFATYVLTSEANQLSVEKVLVSIALFDLMKLPLTILPMLSVDIAETQVSVNR INKFLNSEELDPNSVLHDSSKPHPMSIENGEFSWGDEITLRNINIEVKKGSLVALVGT VGSGKSSVVQAFLGEMEKLAGVVNTVGKLAYVPQQAWIQNATVRDNILFGQTYDRKRY NKVIDACALRADIDILSAGDLTEIGEKGINLSGGQKQRISLARAVYSDADLYLLDDPL SAVDAHVGKHIFEEVIGPKGILARKSRVLVTHGVTFLPQVDSIYVIKMGEISESGTFD QLVKNKGAFADFIIQHLQEGNEEEEELNQIKRQISSTADVPELLGTVEKAIKLARTES LSDSISVTSADSLMGGGGSLRRRTKRQDSHDSVASAASLKKKQEVEGKLIETEKSQTG GVEFAVYKHYIKSVGIFLSVATLVLNFVFQAFQIGSNLWLTQWANDQNVANDTGLRDM YLGVYGAFGFGQGFTSFFSDLAPALGSLHAAKVLHSMLLENVLRAPMTMFDTTPVGRI LSRFSKDVESVDQKMPQVINDCIWCAFEVLATIVVISLSTPIFLAVIVPIAFLYYFAQ RFYVATSRQLMRLESVSRSPIYSHFSETVTGASTIRAYNVGDRFIEESDAKVDKNQVC KYPSVIANRWLAIRLEMVGNLIILFASLFAVLGGQTNPGLVGLSVSYALQVTQTLNWL VRMSSDIETNIVSVERIKEYGETKQEAPWELEQDKNKPKNWPQEGRVEFQNFQVRYRE GLDLVLRGVSFNIQGGEKVGIVGRTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMG LHMLRSRLTIIPQDPVLFSGSLRINLDPFEIKTDDEIWKALELSHLKSFVKSLAAGLN HEIAEGGENLSVGQRQLVCLARALLRKTKVLVLDEATAAVDLETDDLIQKTIRTEFKE CTVLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELLDNPKSAFYSMAKDANLV" ORIGIN 1 gttgtagttg tgcggcttgg gaaggaacag ctgttggccc gaaaatatag atccgtttat 61 ttccttgccg ctttacagtt accacatcgc ccgatatagc atacgcatat agcccaattg 121 cacgtggagg aggttgccga gcagtcgagt aaccatggcg gatgacacta gttcgccgat 181 ggacagattc tgcggatcca cgttctggaa cgcaacagag acatggtata ccaacgatcc 241 ggactttacg ccctgctttg agcaaacggc gctggtctgg acaccctgcg ccttctactg 301 ggcgttcgtg atctttgact tttactacct gaaggcgagt ttggacagga atataccgtg 361 gaacaagctg aacgtgagca aagctctggt gaatctgggt ctgctggtaa tcactgccct 421 ggacctaatt atggcgctgg tcaagaaggg cggcgactct gagctgccgc tctacgacct 481 ggatgtttgg ggtcccatca tcaagttcgc caccttcctg ttgctcttca tattcatccc 541 gctgaatcga aagtatggcg tgcagaccac gggatgtcag ttcatcttct ggttcctgct 601 cactgtgctg tcgattcccc gctgccgcac tgaagttcga ctggacgcgg agcgccagaa 661 gattctgaat tcgcaacagc catccgagca ggacttttcc tgggaggagt atcagttcgt 721 tagcttcttt atcttcttca ccttcaccag cattatgctg atcctgaact gcttcgcgga 781 cggaatgccc agacaaacca agtaccagag gggtgagaac gagattcccg aactgtcagc 841 cagtttcctt tcccgcatca cctatcagtg gttcgacaaa atggccctca agggctatcg 901 caacccgctg gaggagaagg atctgtggga cctgaggccg caggacagct gctccgaggt 961 catgcccatc ttcgcccacc actggaacca gaacgtgcgc aagaactaca agaacaaggc 1021 gcgcgtagaa cccaaggcgc agtttagcaa tggcaacgtg acctttgaga atccccacgg 1081 tgagaagaat ggccgcaaga agggcatggc cagtattatg ccgccaattt acaagtcctt 1141 cggaggcgtc tttctgttcg gcgccctaat gaagctgttc accgacaccc tgacatttgc 1201 ccagccccaa gtcctgagtt tgatcatcag cttcgtcgag gcccaagatg ccgagcccga 1261 atggaagggt atcttatacg ctgtcctgct tttcgttttg gccgctgcac agacctttat 1321 tctggggcaa tatttccacc gaatgttcat tgtgggcctg cgaatcagga cagctttgat 1381 caatgccatc taccgcaagg ccctgcgcat ttcgaactcc accaaaaagg agtccaccgt 1441 gggcgagatc gtcaacctga tggccgtgga tgcccagcga ttcatggaac tgacaaccta 1501 cttaaacatg atctggtcgg cgccactgca gatcggtcta gccctgtatt tcctttggca 1561 gcaactggga ccgtctgtgc tggccggttt ggctgtgatg attatcctga tccctgtgaa 1621 cggagtgatt gccagtcgca tcaagaccta tcagatcaga cagatgaagt acaaagatga 1681 gcgtgttaag ttgatgaacg aagtactgag tggcattaag gtgctcaaat tgtacgcctg 1741 ggaaccgagt ttcgagaagc aagtgctgga catccgtgac aaggagattg cgacgctgcg 1801 ctccactgcc tacttgaacg cgggcacttc gttcttgtgg tcctgtgcac cgttcctggt 1861 ttccttggtc acgttcgcca cttacgtgct aaccagcgag gcgaatcagc tgagcgtcga 1921 gaaggtgtta gtctcaatcg ccctcttcga cctcatgaaa ctcccgctga ccatcctgcc 1981 catgctgagt gttgacatag ccgagacgca agtttccgtg aatcgtatca ataagttcct 2041 gaacagtgag gaactggatc ccaacagcgt tctccacgat tcctctaaac cccatccaat 2101 gagcattgag aacggcgagt tctcgtgggg tgatgagatc acgctgcgca acattaacat 2161 cgaggtgaag aagggcagcc tggtggccct ggttggcacg gtcggttccg gcaagtcgtc 2221 tgtagtgcag gcattcctcg gtgaaatgga aaaacttgcg ggcgttgtca acactgtggg 2281 caagttggcc tatgtaccgc agcaggcgtg gattcagaat gcgacggtga gggacaacat 2341 cctcttcggg cagacctacg accgaaagcg ctacaacaag gtgatcgacg cctgtgccct 2401 gcgtgccgat atcgacatcc tgtcagccgg agatctcacg gaaatcggtg agaaaggcat 2461 taatttatca ggtggccaaa agcagcgcat ctcgttggct cgtgctgtgt acagtgatgc 2521 cgatctgtat ctgctggatg atcctctcag cgcagtggac gcccatgtgg gaaagcacat 2581 cttcgaggag gttatcggac ccaagggtat attggcacga aaatcccgcg tgctggtcac 2641 ccatggtgtg actttcctgc cccaggtgga cagcatctat gtgataaaga tgggcgagat 2701 cagcgagagc ggcacattcg atcaattggt caagaacaaa ggcgcctttg ccgacttcat 2761 tatccagcat ctgcaggagg gcaatgaaga ggaggaggag cttaatcaga tcaagcgcca 2821 gatctctagc accgcagatg tccctgagct gttgggcact gtcgaaaagg ccattaagtt 2881 ggcgcgcacg gaaagcttgt ccgattccat ctccgttaca tccgctgata gtttaatggg 2941 cggaggagga agtcttcgcc ggcgaactaa gcgacaggac tcccacgatt ccgttgcctc 3001 agccgcttcc ctgaaaaaga agcaggaggt cgagggcaag ctgattgaaa ctgagaaatc 3061 gcaaaccggt ggcgtggagt tcgcagtgta taagcattat atcaagagcg ttggcatttt 3121 tctatcggtt gccacattgg tactcaactt tgtattccaa gctttccaaa tcggctcgaa 3181 tctgtggctc actcagtggg ctaacgatca aaatgtcgcc aacgacactg gcctcaggga 3241 catgtatctg ggtgtttatg gtgccttcgg atttggccaa ggtttcacgt cattcttttc 3301 ggacctggct ccggcgctgg gtagtttgca tgccgcaaaa gtcctgcact cgatgctcct 3361 cgaaaatgtg ctgagagcac caatgaccat gttcgatacg acgccggtgg gtcgcatctt 3421 gtcccgattc tcgaaagacg ttgaatcggt tgaccagaaa atgccgcagg tcattaatga 3481 ttgcatttgg tgtgcattcg aggttctggc taccattgtg gttattagtc tgtccacgcc 3541 aattttcctg gccgtgatcg tgcccatcgc cttcctgtac tacttcgccc agcgtttcta 3601 cgtggccact tcccggcagc tgatgcgtct ggaatccgta tcccggtcac caatctactc 3661 gcatttcagc gaaactgtca ccggagcatc gactattcgt gcctacaatg tgggagatcg 3721 ctttattgag gaatctgatg ccaaggtgga caagaaccag gtttgcaagt acccgtccgt 3781 gattgccaac cgttggctgg ccattcgttt ggagatggtg ggcaatctga ttattctgtt 3841 cgcatcgctt ttcgccgtcc tgggaggtca aaccaatccc ggcctggtgg gtctgtcggt 3901 aagctacgcc ctgcaggtga cccaaaccct caactggctg gtgcgcatgt catccgacat 3961 cgagacgaac atcgtgtccg tggagcgcat caaggagtat ggcgagacaa agcaggaagc 4021 tccctgggag ctggagcagg acaagaacaa gcccaagaac tggccacagg agggacgcgt 4081 tgagttccag aacttccagg tgcgctatcg cgaaggcttg gatctggtgc tgcgcggtgt 4141 tagtttcaat atccagggtg gcgagaaggt cggcattgtt ggtcgcactg gtgccggcaa 4201 atccagtctc acattggcct tgttcagaat aattgaagct gccggtggtc gcatctccat 4261 cgatggcgtg gacattgcct caatgggtct gcacatgttg cgttcccgcc tgacaattat 4321 cccccaggat ccagtgcttt tctctggttc gctgcgcatc aacttggatc cctttgaaat 4381 caaaaccgat gacgaaatct ggaaagctct agagctgtcg catctcaagt cctttgtaaa 4441 gagtttggca gctggtctga atcacgagat tgccgagggt ggtgagaatc tgtcggtggg 4501 ccagcgccag ttggtttgct tggcgcgtgc cctgctgcgt aagaccaagg tcctggtgct 4561 ggacgaagcc actgccgctg tggatctgga aactgatgat ttgattcaga aaaccatccg 4621 aacggagttc aaagaatgca ctgttctcac cattgcccat cgcttgaaca ctattttgga 4681 ctcggacaag gtaatcgtgc tggacaaggg ccagatcatc gagttcgcct cgcccacgga 4741 gctgctggac aatcccaagt cggccttcta tagcatggcc aaggacgcca atctagttta 4801 agatccatga atgttaactt gaaactccac gaaactcaaa cggaagagtg agtgccccaa 4861 aacaacaaac tttaggaata tagatgtacg aaaagaaaat cattcaacgg tagctttaag 4921 ccatttggca ctgacagctc tacctcatgg ctagaacaag caactatgag acaaagcaag 4981 caaacaaaca caacaatgga acaataagcg aaagaaatta gcaaatacca actaaatgtt 5041 cattagacta agcgaaataa ttcaagccag ttgcgccttc gtcggttacg ctatgttcgt 5101 ttttattatg tatatgtatg tatttacata gtcaagtgta tttttctatt gtctattgta 5161 cttagttttc tatgcaacaa gaaccggtaa cagcaggaga gatggcaagt tggagcatta 5221 taccgtaaag aaaaaaaata actcttatgt atgccacata tttatgtact taaattaaca 5281 aatcagaaga ttgagatact acttaaactc cctcaagaat ttttgccttc aactgataag 5341 atcagtacga aaaacggtca atgtagttaa atcaatttat tgaaactttt gtagattgta 5401 tacttatatc aaaaataaac aaaacaaaat cccaatg //