Dbfetch
LOCUS NM_167047 5767 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster integrator 6, transcript variant B (IntS6), mRNA. ACCESSION NM_167047 VERSION NM_167047.2 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 5767) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 5767) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 5767) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 5767) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 5767) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 5767) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 5767) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 5767) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 5767) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 5767) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 5767) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 5767) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 5767) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 5767) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 5767) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 5767) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 5767) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 5767) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 5767) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 5767) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 5767) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 5767) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 5767) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jan 16, 2013 this sequence version replaced NM_167047.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..5767 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..5767 /gene="IntS6" /locus_tag="Dmel_CG3125" /gene_synonym="CG3125; Dmel\CG3125; Int6; l(1)G0060" /note="Integrator 6" /map="5B4-5B6" /db_xref="FLYBASE:FBgn0261383" /db_xref="GeneID:31496" CDS 594..4448 /gene="IntS6" /locus_tag="Dmel_CG3125" /gene_synonym="CG3125; Dmel\CG3125; Int6; l(1)G0060" /note="CG3125 gene product from transcript CG3125-RB; CG3125-PB; IntS6-PB" /codon_start=1 /product="integrator 6, isoform B" /protein_id="NP_727026.1" /db_xref="FLYBASE:FBpp0070807" /db_xref="GeneID:31496" /db_xref="FLYBASE:FBgn0261383" /translation="MTIILFLVDTSSSMCQKAYVNGVQKTYLDIAKGAVETFLKYRQR TQDCLGDRYMLLTFEEPPANVKAGWKENHATFMNELKNLQSHGLTSMGESLRNAFDLL NLNRMQSGIDTYGQGRCPFYLEPSVIIVITDGGRYSYRNGVHQEIILPLSNQIPGTKF TKEPFRWDQRLFSLVLRMPGNKIDERVDGKVPHDDSPIERMCEVTGGRSYRVRSHYVL NQCIESLVQKVQPGVVLQFEPMLPKEATSATAGEAAGASTISGMGISSTSGAGPAPDI VFQPVKKMIYVQKHITQKTFPIGYWPLPEPYWPDSKAITLPPRDAHPKLKVLTPAVDE PQLVRSFPVDKYEIEGCPLTLQILNKREMNKCWQVIVTNGMHGFELPFGYLKAAPNFS QVHLYVLAYNYPALLPILHDLIHKYNMSPPSDLMYKFNAYVRSIPPYYCPFLRKALVN INVPYQLLQFLLPENVDNYLSPTIANQLKHIKNTAKQDQENLCMKVYKQLKQPKPPYR QVETGKLFTGAPLRRDLVRHPLLRDIFSKLHGEIDPVENYTIVVPQPTHQSSAKSHRN PFDIPRRDLVEEIAKMRETLLRPVSLVAKDSGHCLPIAEMGNYQEYLKNKDNPLREIE PTNVRQHMFGNPYKKDKHMVMVDEADLSDVAPMKSPNGNGPGGAPPGSPSGSGSPTGP GPSSPGSSPGGGSGPGMPGMPGMGGGMSGLMLGAGGSGGSSKKLDGTSRGRKRKAGPL PRSFEFRRSSTDSRSSSSGSESSTTGSAPGSPIPGATSSISGCDSAMGADGGPSSSCF DEDSNSNSSFVSSTSEASASDSGMSNSHLDPLRISFVFIEEETSDQDTPLNGYVHNFI NGISDDAETGETEAVPGGASLPGASSANEPSSIGASPAVSATPATSVIPASNGSEVCS AVAAGSSSSISSSASSPGVLYVPLNGLTTHAAYSSNLGGPSSPLDNLSSLGGAAGGGG SGLLGVSKPGSLPLANGYGHGHSSAISPPSPLSLVPLSPLGTSTPAASSSGLSSSSAY FSHNDINDASEISRILQTCHNGTSSGSSVGAGASNSNLNGNGSTESGGGVSSDDHASL GGNSFDALKRTAGTAGSTAAGNPHYYWASGLNHHNNNNSSAAGAASGSTLSNNHNHRG HNNSSPNKLEVKINSSCGSSPTHNNGGMGSPGQSLPLIFTEEQREAARLHNVELRLQI FRDIRRPGRDYSQLLEHLNLVKGDQDMQSDFVDMCIVESLRFRRHRMASSIQEWWDRK QQLTAVGTNEATPSAEQAVAKS" ORIGIN 1 ttatttcttc accgtttttc gagctctgac aaccctgccg ctgctgcata agtgaattcc 61 gacaaagagc cgtgtcattt tgttggccaa aacatcgctg cgccgagatt aattagacgg 121 aaaaaactcg attacttgaa gtgctcggcc ctatatcgtt ttggtttaaa cgtttcgctg 181 ttgttgttgt ttctccagtc caaatgtcag ctgttgcacg caacatgtac catagaagcg 241 gaacagcgaa acgcagaaaa agagcaaatc gatcaagccc aggacaagaa caacaagtgc 301 aagagaatcg gcagcaaaaa caacaagcag ataaagagag ctgctaacaa cgtaaacaaa 361 acctaaacac ctatacacac gcaaagggag atagcaacaa atacaaaaac aacaaccaca 421 aatagcaaga atatagcaga aagcgagaga gaaggagagg gagaaagtgc acctgagagg 481 ggaaataaaa gatcaacgat aaaagataag agataaagat atcagagaga gacggaaaga 541 cacgcaaatt gggaagagga agaggtccct cgaacgcagg atcaatcatc gccatgacaa 601 tcatactctt cctggtggac acttcgtcgt ccatgtgcca gaaggcgtat gtgaatgggg 661 tacagaaaac gtatctggac attgccaagg gagccgtgga gacgtttctc aagtatcgcc 721 agcgtacgca ggattgcctg ggagatcgct acatgctgct cacattcgag gagccaccgg 781 caaacgtgaa agctggatgg aaggagaacc atgccacctt catgaacgag ctgaagaacc 841 tacagagtca cggcctcacc tcgatgggtg aatcgctgcg caatgcgttc gatttgttaa 901 atctgaatcg catgcagtcg ggcatcgata cgtacgggca gggcaggtgc ccgttttatc 961 tggagccatc ggtcatcatt gtgattacgg acggcggtcg ctattcgtac cggaatggtg 1021 tccatcagga gatcatactg ccgctaagta accaaatacc gggcacaaag tttactaagg 1081 agccatttcg ctgggatcag cgcttgtttt cgcttgtcct ccgcatgccg ggcaacaaga 1141 ttgacgagcg agtggacggc aaggtgccgc atgacgattc tcccatcgaa cggatgtgcg 1201 aggtaaccgg cggacgttca tatcgagtgc gaagccacta cgtactcaac cagtgcattg 1261 aaagtcttgt ccaaaaggtt cagcctggtg tggtgctgca gttcgagcct atgctgccca 1321 aggaggctac ttccgctacc gctggcgaag cggcgggtgc gagcacgata tccggcatgg 1381 gaatatcctc aacgtccgga gcgggtcccg ctcccgatat tgtcttccag ccggtaaaga 1441 agatgatcta cgtgcagaag cacatcacgc agaaaacctt tcccatcggc tattggccac 1501 tgccggagcc ctattggccg gactccaagg cgattacatt gccgcctcgc gacgcacatc 1561 ccaagctgaa ggtcctgacg ccggcggtgg acgagccaca gctggtgcgc agcttccccg 1621 tcgacaagta cgagattgaa ggctgtccgt taacgctgca gattctcaac aagcgcgaga 1681 tgaacaagtg ctggcaggtg attgtgacca atggcatgca tggattcgag ctgccctttg 1741 gctacctaaa agcggcgcct aacttttcgc aggtacacct ctatgtactg gcctacaatt 1801 atccagcgtt gctgcccatt ctgcatgacc tcattcacaa gtacaatatg agtccgccga 1861 gcgatctgat gtacaaattc aacgcctatg tgcgttcaat accgccgtat tactgcccgt 1921 tcctgcgcaa ggcgctggtc aacatcaatg tgccgtatca gctgctgcag tttctgctgc 1981 cggagaatgt ggacaactat ctgtcgccaa cgatcgccaa tcagctgaag cacatcaaga 2041 atacggccaa gcaggatcag gagaatcttt gcatgaaggt gtacaagcag ctgaagcagc 2101 cgaagccacc atatcgccaa gtggagacgg gcaaactgtt cacaggtgcg ccgttgcgca 2161 gagatttggt gcggcatcca ctgctccggg atatattttc caagttgcat ggggaaatag 2221 atcccgtgga gaattatacg attgtggtgc cgcagccaac gcatcagtcg tcggccaagt 2281 cgcatcgcaa tcccttcgat ataccgcggc gggatttggt ggaggaaata gccaagatgc 2341 gtgagacctt actgcgaccc gtctcgctgg tggccaagga ctcgggccat tgcctgccca 2401 tcgccgagat gggcaactac caggagtacc tcaagaacaa ggacaatccg ctgcgtgaaa 2461 tcgagccgac gaatgtgcgg cagcacatgt tcggtaatcc gtacaagaag gacaagcaca 2521 tggtgatggt ggacgaggcg gatctgagcg atgtggcgcc aatgaagtcg ccaaatggca 2581 atggaccggg tggagcgccg cccggctcac cttccggatc gggctcgccc actggaccgg 2641 gtccctcatc cccgggctct tcgcccggcg gtggttcggg tcccgggatg cccggaatgc 2701 cgggaatggg gggtggaatg tcaggactga tgctgggcgc aggtggcagt ggcggatcct 2761 ctaaaaaact ggacggaacg tctcgtgggc gaaagaggaa agcaggaccg ctgccacgta 2821 gctttgaatt ccgtcgatca tctacggact cgcgatcttc gagctccggc tccgaatcat 2881 caacaacggg tagtgcacca ggatcaccga taccaggcgc cacgtcatcc atatccggct 2941 gcgattccgc catgggcgct gatggcggtc ccagttccag ctgtttcgac gaggacagca 3001 atagcaacag cagctttgtg agctccacat cggaggcctc ggccagtgat tcagggatgt 3061 caaactcgca tttggatccc ttgcgaatca gtttcgtttt catcgaggag gagaccagcg 3121 atcaggatac gccgctcaat ggttatgtgc acaatttcat caatggcatc agcgacgatg 3181 cagaaacggg cgaaacggaa gcagttccag gcggggcatc cctgccgggt gcgtcttcag 3241 ctaacgaacc gtcgtcaatt ggagcatcac cagcagtttc agccacgcca gcaacatctg 3301 tgatccccgc cagcaatggc agcgaagttt gctccgccgt cgcggccggc agcagcagtt 3361 ccatcagctc cagcgccagt tccccgggcg ttctctacgt gcccctcaac ggactgacca 3421 cccatgcggc ctacagcagt aatctgggtg gtccgagctc gccgttggac aaccttagct 3481 ccctgggtgg agcggcgggt ggcggaggat cgggactact cggtgtcagc aagccgggat 3541 cgctgccact ggccaatggt tatggacacg gtcatagttc agccatttcc ccaccttcgc 3601 cattgtcctt ggtgcctcta tcaccattgg gaacaagtac gcccgctgcc agcagctcgg 3661 gactatcgtc tagttccgcc tacttcagcc acaatgacat caacgatgcc tcggagatct 3721 cgcgcatact gcagacctgt cacaatggaa ccagcagtgg ctcctcggtc ggagcgggcg 3781 caagcaacag caatttgaat ggcaatggca gcacggagag tggcggagga gtctcatccg 3841 acgatcatgc ctcgctgggt ggcaacagtt tcgatgccct gaaacggaca gcgggtactg 3901 cgggcagcac tgcagcggga aatccccact actactgggc cagtggtctc aatcatcaca 3961 acaataacaa cagcagcgcc gctggagcag ctagcggttc gacgttgagc aacaatcaca 4021 accaccgggg tcacaacaac agcagcccca acaaactgga ggtgaagatc aactccagct 4081 gcggctcctc accgacgcac aacaacgggg gcatgggctc accgggacag agcctgccgc 4141 tcattttcac cgaggagcag cgcgaagcgg cccggttgca caacgtcgaa ctacgattgc 4201 agatcttccg tgatatacgg cgacccggcc gagactacag ccagctgctg gagcacctga 4261 atctggtcaa gggcgaccag gatatgcagt cggatttcgt ggacatgtgt atcgtggaat 4321 cgctgcgctt ccgccgccat cgcatggcgt ccagcataca ggagtggtgg gatcgcaagc 4381 agcagttaac tgccgtggga accaatgaag cgacccccag cgcggagcag gccgtcgcca 4441 agagttaacg atggctcatg tggcaccact gagcccgcgg ggtcatccaa tccatctgtc 4501 tgtgatgtca acaaaatcga aatcgaaatc taaaccgaaa ctgggaaggg gaagagcagc 4561 cgcggaagcc aagaattctc gtcaatttcc atatactgta aataattgcc aggacaggta 4621 gcccacagga tctggatggg gatcaacgca taccaaacaa gcaacaataa tattaacaat 4681 ttccatatac tgtaaataat tgccaggaca ggtagcccac aggatctgga tggggatcaa 4741 cgcataccaa acaagcaaca ataatattaa caacaaaacc aacaagcagc cacaattcta 4801 aatgagagaa aacaccacat ttttagggca agctagctac atgtaattat aacatatata 4861 taaataaata cttaagctag ccgttagtta gcaatagaat ataaagtata aagcgaaggg 4921 attttgtagc agccgtttca gttgtagttt tttttttact tagtataaat atgtaagcgt 4981 aaattaaaat ttactcttga gcttaggaat aattttaaat agacttagat aaattaagat 5041 aaatctaagt gtagtgtatg tgtataaaaa aaaagggaaa agtttaggaa aagcttgagc 5101 ttaatgagcc ccacacgttt tagccaattt tttgttggac ctgtttcaag aacactttgc 5161 tttgatttta gccaaaacga atagagaacg taaaaaacaa aagcgatgac ccttcaaaaa 5221 cagatatata tgtgtatgtt tatatacata tatgtatata gaggatatta cataaatcgg 5281 gtcagcgttt tattattaaa aagaattgta ttaccttgta tttccttgaa tcctccaata 5341 tattatttgc tattatgtta tgtttatttt ataaaatatt tatgcgaatt gtaatgtgag 5401 catagcctgt agaaaggcag acaaaacgat aagcgaaaac gtacagtttg ttatatacat 5461 atagaaaaac aagaaaaaag taatacattt ttgcactatt tttttacgtg tatgtttgta 5521 tgcatggcct gtgagtaatt gagatataac aaaaacgaaa aacacaaaga gaaaacgttt 5581 actagtagtt aggcggcggg cagtgtttta gaactgcttc attattaaat aatgatgtac 5641 aatttagagt ctgcgtattt aacaaatttc ataagacaac caccacaaca gaatcaacag 5701 agcagcagca aagcaaactg aaatcaatac gaaatcaaac gaaaataaaa agaggagcat 5761 tgcattc //