Dbfetch
LOCUS NM_166968 11128 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster dunce (dnc), transcript variant N, mRNA. ACCESSION NM_166968 VERSION NM_166968.3 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 11128) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 11128) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 11128) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 11128) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 11128) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 11128) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 11128) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 11128) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 11128) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 11128) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 11128) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 11128) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 11128) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 11128) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 11128) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 11128) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 11128) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 11128) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 11128) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 11128) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 11128) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 11128) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 11128) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jan 16, 2013 this sequence version replaced NM_166968.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..11128 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..11128 /gene="dnc" /locus_tag="Dmel_CG32498" /gene_synonym="CG10791; CG10792; CG10797; CG14267; CG14268; CG32498; Dmel\CG32498; Dnc; DNC; Dunce; Dunce PDE; EG:140G11.4; EG:96G10.7; EG:BACN05I09.3; EG:BACN5I9.2; fs(1)M42; PDE; PDE4; PDEII" /note="dunce" /map="3C9-3D1" /db_xref="FLYBASE:FBgn0000479" /db_xref="GeneID:31309" CDS 3583..6534 /gene="dnc" /locus_tag="Dmel_CG32498" /gene_synonym="CG10791; CG10792; CG10797; CG14267; CG14268; CG32498; Dmel\CG32498; Dnc; DNC; Dunce; Dunce PDE; EG:140G11.4; EG:96G10.7; EG:BACN05I09.3; EG:BACN5I9.2; fs(1)M42; PDE; PDE4; PDEII" /EC_number="3.1.4.-" /EC_number="3.1.4.17" /EC_number="3.1.4.53" /note="CG32498 gene product from transcript CG32498-RN; CG32498-PN; dnc-PN; dunce phosphodiesterase" /codon_start=1 /product="dunce, isoform N" /protein_id="NP_726856.1" /db_xref="FLYBASE:FBpp0070495" /db_xref="GeneID:31309" /db_xref="FLYBASE:FBgn0000479" /translation="MIATLFIIFAFIRAFPWSRKRGRPALALTLMPEGGEDHRGDLNQ KGENNNRPRPSISLANNGEAMAPRTRRKSSKFHEVTFSGSVGGGDSDGGGEAINGGNL DVSPSKRHSLSTTTSNSSSAPYRYLSGSSRSRGSRGDCHEYYQLQQHSSSLSNGNRGN RGLSQRSDTMATEAEGEEFDVDPMDEDDEDQTYDRETEEFYSNIQDAAGTGSSSRSKR SSLFSRSDSSATTTSSSGGGTFTGGKRRSAASILSSSMCSDLMTSDRRSSTATEYSVK SVTTGNTSQRRSSGRIRRYVSRMTIAGARRRTTGSFDVENGQGARSPLEGGSPSAGLV LQNLPQRRESFLYRSDSDFEMSPKSMSRNSSIASESHGEDLIVTPFAQILASLRSVRN NLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQ LETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYICSTFLDKQQEFDLPS LRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTGERLPT FGVETPRENELGTLLGELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPP KTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAA CIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKK QRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENL VHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVG FIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMIPPSPPPSGVDENPQEDRIR FQVTLEESDQENLAELEEGDESGGESTTTGTTGTTAASALSGAGGGGGGGGGMAPRTG GCQNQPQHGGM" ORIGIN 1 caacaacagc acagcggcag tagcaacaac gcagtaacag aagcagtagc agcagcaaca 61 gcagcagcaa cagcaacagc aacatcactg tggcaaccgc aacagcacag cagcagcaac 121 atcagcacgt gtgcgtgccc caaacagcag agagataaat acataaaacg ccgagaaatt 181 caagagaaaa gcaagaaaaa agttaaggct aaaaagcaat taaaacaaat tgtgccgtaa 241 gtcaagtcgg tgggcttaca gcccagtccc ccgcaaataa aagaaaaaat aaaaaaaaaa 301 ataaaaaaaa aaatagaaag aaacaaagaa aactgtaaga aaaaaagaac agaaatacac 361 gagtaaccac cgcaggatcc gcaggacaac gtacccaccg atcccaaaaa agaaacgcac 421 gagacaaaac aaaaaaaaaa cgaaaaaaag tgaaataaaa ggaaaccatg tcccaggaga 481 gtaatggtgg cccagcagca ggaggcggag cagcagcagc accaccacca ccaccacaat 541 acataataac cacacccagc gaggtggatc ccgacgaagt gcgctccatg gccgacctag 601 agctgggatc ccccgaaaag caggtgcagg tacagagtca aaagttctcc agcacgtcga 661 gcaccaccaa ggtggccacc cactcatttt cgatgagcag tagtgccggc actactgggc 721 agcaaagcaa acaggacagc gcccagcaaa tccaacagct tcagcagctc caacagctcc 781 agcaactcca gcagcagcag cagcagcaac agtcccagag aatcatatcc agttcgacga 841 gaagccagag cctgcagtcc agcacaattg tgggcgaggc cactacaatt acgagcggag 901 ctgcccaaat cctaagcgcc tcggcggcgg cttcgctggc ccagcagctg aaggcccaaa 961 gctccacctc gattatcaca agcagcgagc agaggacgag cacaagcacc agtagcagca 1021 gcagcacccg ttacatagcc agcggctcga gcaacctggc cggtggcaat tcgaattcgg 1081 ccagctcggc cagcagcaag actcgcttcc agagtttcct tcagcagccg gagggtgcgc 1141 acggttttct gacggcccat cagaagcatg tgcgtcaatt tgtgcgctcc acatcggcac 1201 attcggaggc ggcagccgga gtggctgggg cacgggcgga gaagtgcata cgcagcgctt 1261 ccacacagat cgatgatgcc agtgtggccg gtgtggtgga gtcggctggt aacttgactg 1321 acagctccgc cacgggagga tccatgcagc tgtcgatgag caaactgggc ctgcagcagt 1381 catcgtccat attgatctcc aagtcggccg aaacgatcga gatgaagagc tcgtcggcgg 1441 gcatgcgcac ccagttgaca ttgagcggtg gcttcttggc gccgccgggc aatcgaaaaa 1501 taaccatttt gagtccaatt cacgcaccgc ccggtctgca tgatatgctc aagcgggccc 1561 aaggacgatc gccgctatcg cccaggatca gctttcccgg cagcgattcg gacctctttg 1621 ggtaagtcga ttatgtgccg cctatcttta atgtcagcga aaatctttgg taagcctatt 1681 tcattgggaa atcaaagtaa agtaaatgta agctagatat tgcgcatacg ccatgtgaaa 1741 cgggaaattc cacaataatg gtaattcagt agcaatgagc tacagatgcg gcataaactt 1801 aaacagcatt ctcaaaactg gctttaatgt tgttgtgaac gggtccacta tttgtactcc 1861 atatatttgg tgtttttttt tttttgcttt ttttttatat ttgaaagggg gccggtctgc 1921 attgttagtg cttttgagat aagagcttgg tggttagctg gtgttgttgt agttgcaaac 1981 tgataagagt ccaaagagtc ggcacgcttt gtagaatcca ccgaaagcca ccagaaaagc 2041 aaataaattc gaggctattg tcgattttat tttttatcac atgtgataaa tgaatatggg 2101 aaagcagccg agcgattagc gaaccaaagg aataaaccgt tgaggatttc acatattttc 2161 ttcttcttca tgactcttgg ccactgatca aaacgcacta tatttttttc tctttatcta 2221 tatatgtata tatttgggaa aagcttacgt gtgtgtaatt acttcctaac ttcgaaaaca 2281 gttgcatttg cgagttaatt aatttgaaaa aaaaaaaaat ggccattaaa ttgattgcgc 2341 atttgacttg attgcagaaa ccagaaaatg gcttaattta ttaagctggc aaagtatgac 2401 accgaattta tggctgcata aatcacacat gtgtacttac atgtgtatgc agattatact 2461 acatgtgtct gaatttgaat tccccaaaca acaattgaaa agtcccctct tttttctata 2521 tatctatgta catacatatt tacatttact ttatatgtat gtgtatattt tcgccagact 2581 tttttgcaca ccccaatttt tccggcattt ttcctttttt tttttttttg agtctttgtg 2641 caagaagtta aaaaatgtaa aagtaatgaa aaaagcaacg acgacgctat gtctgcccga 2701 tctgcttata attggatttc cgctgtgtgc taaagagaga gggctatact agaaggagag 2761 ggcgctactc tgcgagtgag agggcattag gcggcggcag ctgtttgatg atgaatctca 2821 agtcgctgtc tcattacaac tttcaatttc aattgcttct ttcgcttcta ttcgccctct 2881 cgttttcgca ttatgcttag catctacgct ctcacgcatg gctcttattt taggctacac 2941 cgcgaataac tttcgtattt ttacgcccgt taatgttgaa ttataagtgt ctagttgtgc 3001 accttaaatt gccaccttaa gtttgcctat ttattatgtt tgtataggaa ttgtatttgg 3061 aacatcgata gaaggcatgc tttgaagttc aacaagtatt tcgctcagtg caatagcctc 3121 ctctcgctcg cactcccagc tgttggcgcc tggctcgcct tcgcctcaat tcgaattcgt 3181 tattcgcctc gcttcgttcg tttttcgccg ccaactgctc tgccggcggc gacagcgacg 3241 ccggcgcagg gtctcgtttt cgctttcgct tcgcatcgtt ttcatcgttt tcatcgtctc 3301 cgtcatataa caacgttcgc cgttcgctcc gcacacacaa tttgcgttaa aaaaaaagtt 3361 ccgcaaaatc gcaattcgcg aaaatcgtgc acaattcgtg aaacgaaaat cgaaaacgaa 3421 cttagctaaa ataagagcaa gtgcaagaca aacgaaatta aaaacctatt taaaaaattt 3481 aaaatccgac aacgaaatca aaatgcccaa ggatgtgcgc gccattttct agagtacgaa 3541 atacaaattc cttgggaaag aagtagagat ttttgtgaca agatgatagc cacactgttc 3601 atcatctttg catttattcg cgcctttccg tggagcagaa aacgaggtcg tcctgccttg 3661 gccttgaccc tgatgcccga aggcggtgag gatcatcgcg gcgatctgaa tcaaaagggt 3721 gagaataaca atcggccgag accctcgatt tcgttggcca acaacggcga ggcaatggcg 3781 ccgagaactc gtcgaaaatc atcgaaattc catgaggtca ccttcagtgg cagcgttggc 3841 ggtggcgaca gcgatggtgg cggcgaggcc atcaatggtg gtaacctcga tgtaagcccc 3901 agcaaacgac actccttgag caccaccaca agcaactcca gctcggcacc gtatcgatat 3961 ctgagtggta gcagtagatc ccggggctct cgaggcgatt gccacgaata ctatcaactg 4021 caacagcatt cgtcgtccct atcgaatgga aatcgtggaa atcgtggact aagccagaga 4081 agcgatacaa tggccactga ggcggagggc gaggaattcg atgtggatcc catggacgag 4141 gacgatgagg atcagaccta cgaccgagag accgaggagt tctatagcaa tatacaggat 4201 gccgcaggca ccggatcatc gagtcgcagc aagagatcgt cgctcttctc cagatcggat 4261 agttccgcca ccaccacctc gtcgagcggc ggtggaacct ttactggcgg caagcgcaga 4321 tcggctgcct ctattctgtc ctcatctatg tgctccgatc taatgaccag cgatcgccga 4381 agctccacgg ccacggaata cagcgtcaag tcggtgacca ccgggaatac ctcgcaacgc 4441 aggtcgagcg gacggattcg tagatatgtc tcacggatga caatcgccgg agccaggaga 4501 cgcaccacgg gcagtttcga tgtagaaaat ggccagggcg ctagatcacc gctcgagggc 4561 ggctcaccca gcgccggttt ggtactacag aatttgccgc agcgtcgcga atcgtttcta 4621 tatcgctccg attcggactt tgagatgtca cccaagtcca tgtcccgaaa ctcaagcatc 4681 gctagcgaaa gccatggcga ggatctcatt gtgacgcctt tcgcccaaat tttagccagc 4741 ttacgttcag tgcgcaacaa tttattaagt ctgacaaatg ttccagcatc aaacaaatcc 4801 aggcggccca accaatcgtc gtcggcctcg cgatcaggaa atccaccagg agccccgcta 4861 tcccaaggcg aggaggcata cacccgcctg gccaccgaca caatcgagga gctggactgg 4921 tgcctcgacc agctggagac catccagacc catcgcagcg tctccgacat ggcgtcgctt 4981 aagttcaaac gcatgctcaa caaggagctg tcgcacttta gcgagtccag cagatcggga 5041 aatcagattt ccgaatatat atgttccaca tttttggaca agcaacagga gttcgacttg 5101 ccatcgctgc gcgtggagga taatcccgag ctggtcgccg ccaatgcagc cgctggtcaa 5161 cagtccgctg gacagtatgc acgctcccga tcgccgcgcg gtccgcccat gtcgcagatc 5221 agcggcgtga agagaccgct gtcgcatacg aatagcttta ccggcgaacg tttgcccacc 5281 ttcggtgtgg agacacccag ggagaatgag ctgggcacgc tgctcggcga actggacacc 5341 tggggtattc agatattcag catcggcgag ttcagtgtca atcgaccgct cacctgtgtg 5401 gcatacacca tatttcagag tagagaatta ctgaccagtc ttatgatacc accgaaaact 5461 tttcttaact ttatgtctac tctggaggac cactacgtca aagacaatcc gtttcacaat 5521 tcgctgcatg ccgccgatgt gacacaaagc actaatgtgc tactcaatac accggcgctg 5581 gagggcgtat tcacgccgct cgaagtgggc ggggcgctgt tcgccgcttg catacacgat 5641 gttgatcatc ccggcttaac caatcagttc ttggttaact caagttccga actagcatta 5701 atgtacaatg acgaatctgt tttggaaaat catcatttag ctgttgcctt taaattatta 5761 caaaatcaag gatgtgatat attctgtaat atgcaaaaga aacaacgcca aacattgagg 5821 aaaatggtta ttgatattgt gctgtccacg gacatgtcca agcacatgag tctgctggcc 5881 gacctaaaga caatggtgga aaccaaaaag gtggccggct ccggagtact gctgctggac 5941 aactacaccg atcgcataca ggtgcttgag aatctggtgc actgcgccga tctgagcaat 6001 cccaccaagc cgctgccgct ttacaagcgc tgggtagccc tgctcatgga ggagttcttc 6061 ctgcagggcg ataaggaacg cgaatcgggc atggacatta gtcccatgtg cgatcgccat 6121 aatgccacca ttgagaagtc gcaggtgggc ttcatcgact acatcgtcca cccgctatgg 6181 gagacctggg cggacctggt gcatccggat gcccaggata tactcgacac gcttgaagag 6241 aacagagact actaccagag catgataccg ccttcgccgc cgccatcggg cgtcgatgag 6301 aatccgcagg aggacaggat acgctttcaa gtaacccttg aggaatccga tcaggagaac 6361 ctcgccgaac tggaggaggg cgacgagagt ggtggcgaga gcaccaccac aggcacaacc 6421 ggaaccaccg ctgcatccgc gctaagcgga gctggtggcg gtggcggtgg aggcggggga 6481 atggcaccca gaacgggtgg ctgccaaaac caaccgcaac acggtggaat gtgacggaga 6541 gtcgtgggaa tttatcgcaa attacaggaa aaggctcaca actttttcct attacgttag 6601 tgactactat taacacagaa aaaaccaaaa caaaaaccta aaacgaaaag caaaaaaaaa 6661 aacaaagaaa aactcttgga aaaaatgcaa aaaaaaatcc acaaaaaaaa aaccaaaaaa 6721 cccaagtaag gaaatattaa accaatgttt aaacgcatac aaaaatccaa acagcaatag 6781 caaaactaac gttaaaccta taaagtctag agaaaatcga aaaaggaaat tagaaattta 6841 cttaatggaa cccgagattg atgttgaaaa tacactgaaa aagaaggagg aggccgagct 6901 aactaagata aaatcgtaca tattgttaaa aacaaaacaa aaaaacatag acacactaaa 6961 ttcaagacaa agcaaagata ataagaaaaa ttgataagtt acaaaaaata agacgatacc 7021 gaaaactccc gccccaaaag cctaagaaat cccagtaccc cccccccccc tccactcccc 7081 tttatatata tatatataca atttttgttg catgtgtagg taaatgattt ttgtcaaaat 7141 tcatctgaag tagtacatcc atcagaggca gccccttagc tgagtctcct cttttaatcc 7201 attgactaaa gtgaaatatt taaaaaacag agaatcaggc gaacgaaaag gaataattaa 7261 tatgacctag cttataagag aagttattaa gtttttaaat gttttgcatg cccgaacaga 7321 tttattttac ttgattgatt gataacgcta gatctaactg ataaacgata acagcaacac 7381 atggagtttt ttttttatat aatttagacc acagcgatag aagcgaaaga aaatcaacca 7441 tgtaaagttt aagaacccag tgaattaaac caaaattgaa agccaaccga gttgaaacca 7501 atttaattct aaatctaaat ctaaatccac aacccaaaac ccaaaacccc aagcaacaaa 7561 aaagaaagaa agaaggaaaa gtaaggaaca gtctacagcc agactgtagt tgtatagtaa 7621 tatatatgat ataaatattt tttttaaata ttatttgtaa ataatttaaa tgttggactc 7681 gaatttaaat caagcggcta gcaaatgttg cagctaaact aaaatgaaaa caaagccaaa 7741 aaacacacac ataaataggt aaactaagtg aaaaatgtgg aaaaggaaaa actattgtac 7801 aattagctaa agaatttcca tttcaatttt caatttgaat tgcaatttaa tttgcttcca 7861 gaaatgaatg aaaggagaca agaaaaagat agggagataa accgaaaatt agtttcaaac 7921 gctgtcttcg caaatatttt tcgctatata tatatatata tattacttat aacattattt 7981 tactagttac taagctactt actgagccac acaaatttaa aacgaaagag acaagacacc 8041 aggacaagaa agagaaggag ctttcatgaa tttagtgaac aaacataact ggcaatggcc 8101 acacacacac acacaattta caaagcgaac aacaccaaaa aaaataaata aaaagactct 8161 tcaagcacaa aaaaaactgt ttagttttca gtaaacagta aaaccaaagc aaagcaaaat 8221 aacacacaag atataatccc caaaaaagtc attggctata atatgattac ttaacctaac 8281 ctatacaata tatagatata tagatatatc ctatatgcat atgtaaagtc acgatactgg 8341 cgctggtgcg cggatcgatc aatgtggcag gccaaattct aaatgcgcat aatttaacta 8401 ttgtttacat tatgttttat tgttattaat ttattaccaa aaacgaaaac attatttttt 8461 cagacctagt gctataaatt tcttttttgt gttgaagcgg gcaggatccg cgcataaaat 8521 agtgtttttt ttttttttgt aattacaaat atatataaag atacatacat atatatatat 8581 atatataata tgatatgtga atgaaatgta atgaaatgaa gtggaacctt gatggtctaa 8641 aaatatcatt aaaagctgat ggagatggaa agttgaagaa caagatactt tatagcaatt 8701 taagcagcat tgtaaatgtg cgcttcagaa ctactttttt ttcgaaactt aatcgacctt 8761 cagcaaatac agcaagatat attacctaca ttacaaacat atattattaa ttgaaccata 8821 gttgcgacac aaaacaaaaa tgacggcaag tccatggcaa acttaagcaa aaaccaaaag 8881 ctactttaac aaattgagtg aaataaataa aagaaagaaa acaaacaaaa aaaaaaaaac 8941 acaaaaaaaa accatatgac ttttttctcc tctcacaaaa taaaagcgaa aaacagaaaa 9001 ataaactagt attgtattgt atttgtaaca cgaattttcc tgcgagtgaa cactttacgc 9061 agaaccataa agccggaaac tgaaaaccta cagagattcc gcagcaatcg cggcactggt 9121 atgtgtgtat agctaatagc tatactcatt atgtaattta ccagagtatt aatcgaacaa 9181 tttaaattta catatatgca tatgcatacc aacatactag gaatactagg aatatatgca 9241 gtaacggaca tttgatgtat actcgagttg aaacataacc ctaaccaaat gttgtatgtg 9301 tatgtgtaat tcgatgaact taaaagtcca aagccatacg tgaaaataag aacaagcaat 9361 ttatagtgaa aaagtcgaaa agtatctaaa tgtaattgtt agaaaatgcc aagtaaatcc 9421 gaaagttacc acagagttaa tgaggaggca tcatctatct tgtcatccaa gaaatcccca 9481 aatcaatttt tgactgaaat tgaatcgtcc tagtagaggc actcgattcg tactccttcc 9541 ttacccctac cgcccccccc cctcaccaac ttcctttgcc ccaactattg tactttatcc 9601 aatattttcc tatcgacgtg ccgccaatta tatcagtgta tataaactat ttgaaaatca 9661 cgcatatata tgcacacata gagtttttgt agcgtcatat gtgtcattaa ggatgcccac 9721 ttacatacat atatgaaggg aaataaataa gcaagtaaat atacaataca atacatacat 9781 atatgtgtgt gttgtgggta acgagagatc agcatttgta gcacaggttg gccaaattta 9841 ttgggaataa cgagttgccg aagttgccga agaaaaacca aatgaaaact gtttgttgtg 9901 ctgttagccg taaatgagaa cttttttttg agataactta atacctatat atataaatat 9961 gtattacaat atatgtatct ataaatatat aaaacaggcg acaaaccaaa ttaaaccaaa 10021 taccggaaca aaaaaaaaaa aacgaaaaag aagagagaga aaaaataata caagcgatat 10081 tgaaaatggc acgttttgta ctataatgaa atgagaaaac accaaagacg aatgcaaaac 10141 aaaaaaaaat gcaaacacat aacaaaatat acaagaaata ttcttaacaa aaagaaaaaa 10201 ataccataaa ttgtgcgctg gcgacgacgg ttgtttgaaa aaaagagaaa gcaaaaaaca 10261 ggacatgccg cttgaagtgc cgatcgtaag cgagtccttt cgattcgcaa atcgtcggca 10321 tttcaatcga ttgaagaatc gggagatatt atatacatat agaacacgta acgctggcgt 10381 tactgggcaa acagttaggc attttttttt tttctttttt ggaaatttat acaattacat 10441 atacaaaaag agctcacccc cacaacaaca aggacaactg cagaagaaga acaaaaaaaa 10501 tacacacata catggaaaca ctaacgcgta cacggacagc gatttgccgg aacaaaattc 10561 tgggtatttc gaaccgagaa agggaacgga aacggaaacg gaaacgaaaa tatagaacgc 10621 ggcaagttat ttaacactga aactgatcgg gtgtaactat agtaccgaaa tggggcttac 10681 acaggctgat tcacccaaaa taagtataca tgtattgtag taacgagcgc tggcttttgt 10741 tattaagtta tgtatttgtt tcgattatgt tttgcctctc tcagaatata tatatatata 10801 tatatatata tatatatatg tatattctat gtatatatat atattagtta tgtatgtgaa 10861 aaaagcgtaa tcatttatga aaccaatgaa aatctaacct gaaaacaaag agaaaacccc 10921 aagtcaaata cacaattgca tgcaagagta agtaatatta atgaaatcta agaacaaagg 10981 tcactcccgg gcttaaaaaa aaaaaaagaa gaaaaaaaat gggccgcatg gcaaatgata 11041 aatggtaaaa caaaacaatg agcaggtggc attatgaaca gatttgaatg attacggaat 11101 acagactaaa aatgaaaatg aaaaattt //