Dbfetch
LOCUS NM_165677 9679 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster bruchpilot (brp), transcript variant D, mRNA. ACCESSION NM_165677 VERSION NM_165677.4 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 9679) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 9679) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 9679) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 9679) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 9679) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 9679) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 9679) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 9679) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 9679) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 9679) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 9679) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 9679) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 9679) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 9679) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 9679) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 9679) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 9679) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 9679) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 9679) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 9679) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 9679) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 9679) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 9679) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 24 (bases 1 to 9679) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jan 16, 2013 this sequence version replaced NM_165677.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..9679 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="2R" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..9679 /gene="brp" /locus_tag="Dmel_CG42344" /old_locus_tag="Dmel_CG12932" /old_locus_tag="Dmel_CG34146" /gene_synonym="Brp; BRP; Bruchpilot; Cast; CG12932; CG12933; CG1931; CG30336; CG30337; CG34146; CG42344; Dmel\CG42344; mAb nc82; mAbnc82; Mabnc82; MAbnc82; nc-82; nc82; Nc82; NC82" /note="bruchpilot" /map="45E1-45F1" /db_xref="FLYBASE:FBgn0259246" /db_xref="GeneID:35977" CDS 1184..6406 /gene="brp" /locus_tag="Dmel_CG42344" /old_locus_tag="Dmel_CG12932" /old_locus_tag="Dmel_CG34146" /gene_synonym="Brp; BRP; Bruchpilot; Cast; CG12932; CG12933; CG1931; CG30336; CG30337; CG34146; CG42344; Dmel\CG42344; mAb nc82; mAbnc82; Mabnc82; MAbnc82; nc-82; nc82; Nc82; NC82" /note="CG42344 gene product from transcript CG42344-RD; CG42344-PD; brp-PD; monoclonal antibody nc82; bruchpilot; burchpilot; brunchpilot" /codon_start=1 /product="bruchpilot, isoform D" /protein_id="NP_724796.3" /db_xref="FLYBASE:FBpp0289193" /db_xref="GeneID:35977" /db_xref="FLYBASE:FBgn0259246" /translation="MGSPYYRDMDEPTSPAGAGHHRSRSASRPPMAHAMDYPRTRYQS LDRGGLVDPHDREFIPIREPRDRSRDRSLERGLYLEDELYGRSARQSPSAMGGYNTGM GPTSDRAYLGDLQHQNTDLQRELGNLKRELELTNQKLGSSMHSIKTFWSPELKKERAL RKEESAKYSLINDQLKLLSTENQKQAMLVRQLEEELRLRMRQPNLEMQQQMEAIYAEN DHLQREISILRETIKDLECRVETQKQTLIARDESIKKLLEMLQAKGMGKEEERQMFQQ MQAMAQKQLDEFRLEIQRRDQEILAMAAKMKTLEEQHQDYQRHIAVLKESLCAKEEHY NMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISV LQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLR DQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEA SQSELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQNVQKLMF ETGKISTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAAL QEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKE EMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDY DNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELET LKERSESAQTLLMKAARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILK EKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVE AERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFD KLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKM RDRYEKSQVELRKLQDTDTFGRETRRLKEENERLREKLDKTLMELETIRGKSQYESES FEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIERE KARDKHEKLLKEVDRLRLQQSSVSPGDPVRASTSSSSALSAGERQEIDRLRDRLEKAL QSRDATELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAE REALRQANRSGGAGAAPHPQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQK ELQNAEAELQKTREENRKLRNGHQVPPVAAPPAGPSPAEFQAMQKEIQTLQQKLQESE RALQAAGPQQAQAAAAAGASREEIEQWRKVIEQEKSRADMADKAAQEMHKRIQLMDQH IKDQHAQMQKMQQQMQQQQQAAQQAVQQAAQQQQSAAGAGGADPKELEKVRGELQAAC TERDRFQQQLELLVTELEKSKMSNQEQAKQLQTAQQQVQQLQQQVQQLQQQMQQLQQA ASAGAGATDVQRQQLEQQQKQLEEVRKQIDNQAKATEGERKIIDEQRKQIDAKRKDIE EKEKKMAEFDVQLRKRKEQMDQLEKSLQTQGGGAAAAGELNKKLMDTQRQLEACVKEL QNTKEEHKKAATETERLLQLVQMSQEEQNAKEKTIMDLQQALKIAQAKVKQAQTQQQQ QQDAGPAGFLKSFF" ORIGIN 1 ctcagttctt tgagggtagt tagttggaca acggcgttgc cgaaaacggg ccacctcagc 61 tgccgcacaa tacatttttg gccatgtaca taaaacaaaa gccgtttaaa tcataaacac 121 aaaatgcaat tagccagcga gcgcacgcca cgaaagtcaa caaactaact aagccagtgt 181 catcaactaa attagtgcaa gcagctagcc gaccggaacc ggaaatgccc attgagccgc 241 ctgacaacaa ccacaaacac aatcacaatc gcagtcacca gcaccattgc attggcaacg 301 gccataaaga cgagcaacaa atcgcccaca cacacatgta gttgcagcgc gagtgcgtca 361 gtgtgtgcgg gctctgaaaa ccggaagcgg aagtcgagga gcagcagcag gagcaggagc 421 aggagcaaga ggattaaacg aacgaggagg tgcagtagca ggagcagcag ctagcttagc 481 cagtttttca ttcgcccgca gttcgttaag gaaaatcatt caaaattcat cgcctaagca 541 aagcggatgc cgcacaagaa aaagagagag agagagagag agagagagaa agtggcgaat 601 agatcaatca attaatcaat caaaaccgag catatcaacc gagaggccaa taccaaccag 661 agaaccgaaa tcaaagttca acgttgcatt taaggttgca tccggtagac cagttcaact 721 ccaactgcaa cctccggttc cacgtaccac attccatttg caccccgtgt gtgattgcat 781 gccgcggatg agccgcggat tatgtcacgt gacgattata atccagtaac tagctctggt 841 gtgcgcagtc cgggtcgcgt gcggcgtctc caggaattgc cgacggtcga tcgatcccca 901 tcccgggact acggagcgcc acgcggaagt cctttagctg ccgctgccgg gaaattgcat 961 tagaaccggt gaaccgaccg ggacaacagg actagaaaat ggcccacagc tgagccgttg 1021 gacgctagaa aaagccactg cggaaaggtg caccttggaa aatatcacca tcaactatag 1081 taacactgca accgaaactg aactgaatct gtatctgaat ctgaaacttt gcccggagcc 1141 gtgcgtttga tatcaaagcc tcaaactgga ttacaattat gcaatgggca gtccatacta 1201 ccgcgacatg gatgagccaa ccagtccggc cggagcgggt caccatcgca gccggagcgc 1261 cagcagacca ccgatggccc atgccatgga ctatccaaga acccgctacc aatcgctgga 1321 tcgcggtgga ctcgtggatc cccatgatcg cgagttcata cccattcggg agccccgcga 1381 ccgctccagg gacagatccc tcgaacgggg cctgtaccta gaggacgagc tctatggcag 1441 atcagcgcgt cagagcccca gcgccatggg tggatacaat acgggcatgg gccccacatc 1501 ggatcgagct tatttgggcg acctgcagca tcagaacacc gacctgcagc gggagctggg 1561 gaacctgaag cgggaactgg agctgactaa ccagaagctg ggcagctcga tgcacagcat 1621 caagaccttc tggtcgccgg agctcaagaa ggagcgagca ctgcgcaagg aggagagcgc 1681 caagtacagt ctgatcaacg atcagttgaa gctgctcagc acggagaacc agaaacaagc 1741 tatgctggtg cgccagctgg aggaggagct gcgcctgcga atgcgacagc ccaacctgga 1801 gatgcagcag cagatggagg cgatctacgc ggagaacgac cacttgcagc gggagatcag 1861 catcctgcgc gagacgatca aggatctaga gtgccgggtg gagacccaga agcaaacact 1921 gattgcccgc gacgagagta tcaagaagct gctggaaatg ctgcaggcca agggaatggg 1981 caaagaggag gagcgtcaga tgttccagca gatgcaggcc atggcccaga agcagctgga 2041 cgaattccgt cttgaaatac agagaaggga tcaagagatc ctggcgatgg cggccaaaat 2101 gaaaacgctc gaggagcagc accaggacta ccagcggcac atagcggtgc tcaaggaatc 2161 gctatgtgcc aaagaggagc actacaacat gctgcagacg gacgtcgagg agatgcgcgc 2221 ccgcctcgag gagaagaacc gcctcatcga gaagaagacc cagggcaccc tgcagacggt 2281 ccaggagcgt aatcgcctca ccagcgagct taccgagctc aaggaccaca tggacatcaa 2341 ggaccgcaag atcagcgtgc tgcagcgcaa gatcgaaaac ctggaggatc tgctgaagga 2401 gaaggacaac caggtggata tggcgcgggc ccgtttgtcg gccatgcagg cgcaccacag 2461 cagctccgag ggcgccttga ccagcctgga ggaggccatc ggcgacaagg agaagcagat 2521 ggcccagctg cgtgatcagc gggatcgcgc cgagcacgag aagcaggagg agcgggatct 2581 ccacgaacgc gaggtggccg actacaagat caagctgcgg gccgccgaga gtgaggtgga 2641 gaagctacag acgcgtctgg agcgggcggt cacagagcgg gaacgactgg agatcaagct 2701 ggaggcctcg cagagcgaac tgggcaagtc gaaggccgaa ctggagaagg ccacctgcga 2761 aatgggcagg agcagcgccg actgggagtc caccaagcag aggatcgccc gactggagct 2821 ggagaacgag cggctgaaac acgatctgga gcgttcgcag aatgtacaaa agttaatgtt 2881 cgaaacgggc aagatatcga caacctttgg caggaccacg atgaccacgt cccaggaact 2941 ggatcgagcc caggagcggg ccgacaaggc ctcagccgag ctgcgacgca cccaggccga 3001 gctgagagtc acacagtcgg atgcggaaag agcacgcgag gaggcggccg ccctgcagga 3061 gaagctggag aagagccagg gcgaggtgta ccgactcaag gccaagctgg agaacgccca 3121 gggcgagcag gagagtctgc gccaggagct ggagaaggcg cagagcggtg tctctcgcat 3181 ccacgccgac cgcgatcggg ccttctccga ggtggaaaag atcaaggagg agatggagcg 3241 cacccaggcc acgttgggca agtcgcagct gcagcacgag aagctgcaga actcgctgga 3301 caaggcccag aacgaagtcg atcatctgca ggataagctg gacaaggcct gcacggagaa 3361 ccgccgtctg gtgctcgaga aggagaagct cacctacgac tacgacaacc tgcagtcgca 3421 gctggacaag gccttgggcc aggcggccag gatgcagaag gagcgcgaga ctctctcttt 3481 ggacacggat cgcattcgcg agaagctgga gaagacgcag gtgcaactgg gtcgcatcca 3541 gaaggagcgg gatcaattct ccgacgagct ggagacgctc aaggagcgct cggaatcggc 3601 gcagaccctt ctcatgaagg ccgcccgcga ccgggaggcg atgcaaacgg atctggaagt 3661 tctcaaggag cgctacgaga aatcgcacgc cattcagcag aaactccaga tggagcgcga 3721 cgatgcggtc accgaagtcg agatcctcaa ggagaaactg gacaaggcgc tgtacgccag 3781 ccagaagctg atcgacgaga aggacacctc caacaaggag ttcgaaaaga tgctggagaa 3841 gtacgatcgg gcccagaacg agatctatcg ccttcagtcc cgttgcgata cggcagaagc 3901 ggatagagcc cgcttggagg tggaggcgga gcgatctggc ctggctgcca gcaaggcccg 3961 cgaggatctg cgtaagctgc aggacgagag cactcggctg caggaggcct gcgatcgggc 4021 ggcgctccag ttgagccgcg ccaaggagtg cgaggacaat gcgcgcagcg aactggagca 4081 cagtcgcgat cgcttcgaca agctacaaac ggacattcgg cgtgcccagg gcgagaagga 4141 gcacttccag tccgagctgg agagggtcac ctacgaactg gagcgcgcac atgccgccca 4201 gaccaaggcg agcgccagcg tggaggcggc caaggaggag gcggcccact atgccgtaga 4261 gcttgagaag atgcgcgacc gctacgagaa gagccaggtg gagctgcgca agctgcagga 4321 cacggacacc ttcgggcggg agacgcgacg cctcaaggag gagaacgagc ggctgcgcga 4381 gaagctggac aagacgctca tggaactgga gaccatacgc ggcaaatcgc aatacgagtc 4441 ggagtcattc gagaagtaca aggacaagta cgagaagatc gagatggagg tgcagaacat 4501 ggagtcgaag ctgcacgaga ccagcctgca gctggagctg tcgaagggcg aggtggccaa 4561 aatgctggcc aatcaggaaa agcagcgatc cgagctggaa cgggcgcaca tcgagcggga 4621 gaaggcacgc gacaagcatg agaagctact gaaggaggtc gatcgtttgc gcctgcaaca 4681 gtcctcggtg agccccggcg atccggtccg agcgtcgacg tcctcctctt ccgctctgtc 4741 cgctggcgaa cggcaggaga tcgaccgcct gcgggatcgc cttgaaaagg cgctgcagtc 4801 gcgtgacgcc accgagctgg aggccggtcg cttggccaag gaactggaga aggcgcaaat 4861 gcatctggcc aagcagcagg agaacaccga gtccacgcgc atcgagttcg agcgcatggg 4921 cgctgagctc ggtcgcctgc acgatcgcct cgagaaggcc gaggccgaac gggaagcgct 4981 gcgtcaagcg aaccgtagcg gcggagctgg cgctgccccc catccgcagc tggagaagca 5041 cgtccagaag ctggagtcag acgtcaagca gctggccatg gagcgggagc agctggtcct 5101 gcaactggag aagagccagg agattcttat gaacttccag aaggaactcc agaacgcaga 5161 ggcggaattg cagaagacgc gcgaggagaa ccgcaagctg cgcaacggtc accaagtgcc 5221 gccagtcgcc gctccacccg ccggaccctc tcccgccgaa ttccaggcca tgcaaaagga 5281 gatccagacc ctccagcaga agctccaaga gtcggagcgc gccctgcaag ccgccggtcc 5341 ccaacaggca caggctgcag cggcggcagg agcgagtcgc gaggagatcg agcaatggcg 5401 caaggtcatc gagcaggaga agagtcgcgc cgacatggcc gacaaggccg cccaggagat 5461 gcacaagcgc attcagctta tggaccaaca catcaaggat cagcacgccc agatgcagaa 5521 gatgcagcag cagatgcaac agcagcagca ggcggcgcaa caggcggtgc aacaggcggc 5581 gcagcagcag caatccgcag caggtgccgg cggtgcggac cccaaagagt tggagaaggt 5641 caggggcgaa ctccaggcgg cgtgcaccga gcgggatcgc ttccagcagc agctggagct 5701 cctggtcaca gagttggaga agagcaagat gtccaaccag gagcaggcaa aacagctcca 5761 aacggcgcag cagcaagtgc agcaactgca acagcaggtg caacagctgc agcagcagat 5821 gcaacaactg cagcaggctg ccagtgcggg agcaggcgcc accgacgtgc agcgccagca 5881 gctggaacag cagcagaagc aactggagga ggtgcgcaag cagatcgaca accaggccaa 5941 ggccaccgag ggcgagcgca agatcatcga cgagcagcgc aagcagatcg acgccaagcg 6001 caaggacatc gaggaaaagg agaagaagat ggccgagttc gacgtacagc tgcgcaagcg 6061 caaggagcag atggaccagc tggagaagtc cctacagacg cagggaggcg gagcggcggc 6121 cgccggcgag ctgaacaaga agctcatgga tacgcagcgg cagctggaag catgcgtcaa 6181 ggagctgcaa aatacaaagg aggagcacaa gaaggcggca accgaaacgg agcgtttgct 6241 gcaattggta caaatgtcgc aggaggagca gaacgccaag gagaagacca tcatggattt 6301 gcaacaagcc ttaaagatcg ctcaagccaa agtcaaacaa gcacaaacgc agcaacagca 6361 acagcaggat gctggaccag ctggcttctt gaagagcttt ttctaaacag tgccctcgca 6421 aagccacaga tacacacatc ttgggatgca gatgaggcaa aaggatttta cacgtactac 6481 ttacccaaag cgataatgga aaaccaacca acagcaagat gttaccaaaa gcactgtcta 6541 ctattttgta tactaccgat gccgatacca ataccaacta tgcagtattt ctacgactct 6601 cacacacact atgtacactc tttacacaca cagataaaca cagggacaca cacacacatt 6661 tgtaaatgac accatgtaaa tgcaatgcga aatgcatatt atttgatatt tatgtgtatt 6721 gtgtaattag gttgccgcta tactcaaatt gtggatgcat ttaaaagtca gctcgtatag 6781 cgtactttgt aaactctctt aactttctct ctaactcact aactcaatcc tattcgaact 6841 caaaatcgaa ctcaacttaa agtttatcgt tagccaaaac accaagtcct tcttagccca 6901 attaccccaa ctcgagagtc cttctgtcca tcactttctt ctctctgtcg gtcggagctg 6961 caacacgtag actacgtcct cgggcactgc atccccatcg ccatccccat ctgtaagacc 7021 cacccattag ttctcccact gcgcggatgt gagatggcat tgaaattgaa acgagaagaa 7081 aggcagagca gtaattgcat taattgagtg ctgctttgga cccaaagtgc agcatgcact 7141 tacaattatc gacgatatat cgcatataca tatgtatgct agcctctgtt atagttagtc 7201 aaacatgagc atcctacgcc catcattcgc ccatcagtca cactgtacat aagacattcg 7261 caacggaaaa atatagatac agatacggat acaatacgta gagcaataat tgatagacca 7321 cagataatac aagtatgata tagatacgag taccatatgt aaaattatta caattataaa 7381 attatattgc ctagccttta gccgtgtacc aaagaactat cactacagag cccaaaagga 7441 agatcactac ctaccccatt cagctattat ggatattatc gataaaataa actcgaacgt 7501 caactacaac aagtgcaatc tctattttaa ttagttaaat ctacacgata ccccacgttc 7561 cttagccccc gactaaatag atcgagtcca ctacgcaagc tttacccaag tcagctgtga 7621 atgcgcatag tacgagtact tatagtactt ctagtagatc ggtagttcca actctagtcc 7681 aggtcactcg aaacgttgct tttggtctag aaaaggtgcg aaagtgttat tgttatcaga 7741 catgaatgac ccatgcccct gtaatgcata cttagctata gaggaatagt tgcagatgtg 7801 tacaaactat agagtaccac atattgacta gcatgaacta gtgtttcttt tttttatttt 7861 ttatttaatt gagtgcatat tcttcgttcc ctttaattta aacgtaaaga aagtagaaat 7921 tgaatggaag aattatgatg tacgaagtta gttagaagag agtatggagt tatcactgcc 7981 agtgtaagca agaatatcga tagatgggaa acttaagatc cgtttaatcc tagggcctaa 8041 cattagaata tcatttgact ttcggttact aaagaaacca accacgaaga cattcagcgt 8101 gagacgacga agcaagagac acaacacaat catatcatac aagcctatat catagcccca 8161 agaacgaagg atagctgatc ctagcgcttt aattgtcctt tgatccttca acccattcta 8221 gaacgatcga tttgttaaat tgatagagca cctcctcctc caccctttag gtaatcgatt 8281 aacgaccaag taaactacga tagagctgca ctctctgctt tcttttcggt ttttggtttc 8341 gcagtcgttc gatttgtgta cataagttag ggtcccgctt ttcgcccctc tctctcgcca 8401 aatgagttcc ccacaaagtt cctataccag gaacctcggg tttacggtgc agctggaggg 8461 cagaaagcca tacgagttcg cgagtcaagt aaaaaagtaa atgtttagca accaacacct 8521 ttatgctcga cagaagtgta cataagtgtc tagttatgta agcataacag aagctgtata 8581 atatataaaa gtttactaaa tactaaatac gatataatgt aatcatcaat ctatatccag 8641 accattgaga acacgagaac aattactatc gacaaatcaa accgaacaaa cttcaccgta 8701 ggacacatca ctttggctac ccaagctgca tacaaattac acaccacgtt gacaatacaa 8761 tcacccacaa aatacacgtg aacactgata caccctttgg atgcccccaa tttgtaccac 8821 tcaatcacga tccattgacg ctagatggaa gccaacatat ccgagtcgag gtagcgctaa 8881 tcttatgtta actgtggccc aaccccagat atcacatagt cgaacggggc aatttcctag 8941 cgctacgagt ggatttcttg gtcactcgat cagtaggtca ctcgatcacc gatcaccggt 9001 cactttcacc ttcgatcttg atctcgattt gcagttatag aggatgaaac gtttgccttt 9061 aactacttaa cttaacttac cacgtatcgt attgttagcc tagatagtct caattacagc 9121 agcagcagca gtgacgaaca aactgagatt aagaacatga actaacggtc taactactct 9181 tatagtattt gccgtaacac tttaatcata ttatccccgc cgtcgtgtac cctacttaca 9241 gatacaaata cgaaactatc ggatagcaag gaaagcttcg acaacttttt ctatacaaat 9301 ctagcgaaca taacaataac aagagatata tgatatatga taaatcgaaa agcaaaaccc 9361 aattctcgta taatgtaatt tagcaaattg taaacacaat ataggcagac agacactcgc 9421 tcgcaaacaa aaaccccgaa tatcaggcga tggaatcgat gacagataca taaatgaatt 9481 tatatggtgg tacgagcgtt acctatcgat aaatgctagc gaagaattat tatgtataac 9541 tccagtgtgt acttctctgt acatagacct atatatatat atatatatat atatatatat 9601 atatatatat atatataaat acttacgatt atgactagag caaagcatac gatagatgaa 9661 tataggaata tacggaaac //