Dbfetch
LOCUS NM_143496 11469 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster vacuolar protein sorting 13B, transcript variant A (Vps13B), mRNA. ACCESSION NM_143496 VERSION NM_143496.4 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 11469) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 11469) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 11469) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 11469) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 11469) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 11469) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 11469) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 11469) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 11469) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 11469) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 11469) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 11469) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 11469) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 11469) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 11469) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 11469) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 11469) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 11469) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 11469) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 11469) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 11469) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 11469) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 11469) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 24 (bases 1 to 11469) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Dec 17, 2009 this sequence version replaced NM_143496.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..11469 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="3R" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..11469 /gene="Vps13B" /locus_tag="Dmel_CG15523" /gene_synonym="CG15523; Dmel\CG15523" /note="Vacuolar protein sorting 13B" /map="99C7-99C7" /db_xref="FLYBASE:FBgn0039727" /db_xref="GeneID:43550" CDS 197..11392 /gene="Vps13B" /locus_tag="Dmel_CG15523" /gene_synonym="CG15523; Dmel\CG15523" /note="CG15523 gene product from transcript CG15523-RA; CG15523-PA; Vps13B-PA" /codon_start=1 /product="vacuolar protein sorting 13B, isoform A" /protein_id="NP_651753.2" /db_xref="FLYBASE:FBpp0084871" /db_xref="GeneID:43550" /db_xref="FLYBASE:FBgn0039727" /translation="MFKLESYITPILLSYVAKYVKNFRDEDAQVSLWEGEVTFQNLDL RLEVLEEELNLPVELVSGHIHELSILVPWTKLMSEPVKIVINTIEFVAKLPDSESKQR RASFQREQRRKSKRESVEQPDQTKSPGPASSSSVVNKIINNINLQCHNIILKYVEDDI VVSMNVQTLNFSSAGEDWKPTMVDIHPVSVVMRKLLQVSDLTICLDKRNTAGRIEVCQ EPVLYRCTLECRVLRKYNANTVSTTSTTRIGVFTKSLDINVSSLQFPMVMRLVKMLLE LKPAEFEDDPQNPEDQEAVAEGSESQQGTESAGRSVFWWAWSLLPSFDTEAPSSSCDT PTGHAFDLGVYAEELNFQLKNSEYFTDQSMGGIKRIRYTPILRISLGGLYYERTILKE CDWANVKAGLSSMCMEPLGAYRSDDLVDRNLVNTQEFQQERSFIDKSLFDENYMFAER SWCSYNYADYVARNTDEYMLFRSPVLAFDVIEHRVPKPSSHPVAESQLRDLGVRIQYR LLSAGITFHFSQSFVQVKKVISDLIRPYDYPGYRSESMKDEDRGVPEPENKNSEMTIP DLEYLMGLVPTCNYKIELRNIVVQLYPRQQQDESSAINQHQLTTTVRQSLLPYLQLKI SLVEGTMCGPVNPVRLVQLITHLEEKPRDVVNACYNCFHFNVKNLALMIMNTTPDNGR AKLLNIPRVQVNWNRLLAPHLWRQNEAPLETSEIKSEIITLEFSKRELIIAKRLVPLI SSFSGQDLCDLAHIVANVNVNSDVIKLQSVGTKLNLVYHKYHTHLAAVGSLQGVHTDA VHTKMNIRNVVLSTSKNADNKWLEMQCQFPLEEVHSEQEKIPGTVVCLWLEPFRITTD IYLLQFLNFSDNSGRQITKDKEVETDLESVNQSEPPITQSVSNYSTISASAIAFNDFQ PRRISRNNSRKISVPEETVHLSSERDERHTQAEPLTIPVANKPQPSNFDTTDFVKRLT KMVVLVEIAQAKIDVCEVMMRKTPGHTDVEYTSIRLPHMKVKSGNCEAIQRGNIRGVI PVASNTELLNWVFDLNEFNVCYRRANVTEMIIAPVRTTITLALSFKTSDKVDGSKGKE DKCANTCSINVHVDMSAINIFAQRVKLLHEHCLIISKMYGSLCPDEPASKWQTGKMKP RLEVYTGSAQNYPVIKEFLELDPNFEAPKVKSAPKSSVILFCQWTIPRISFEMENSND FKHSKIVMSLEDLLLNIDKHSDFNKITTKIENFGLNYYEEKHEEWEKIDDLHIKMLGD STNLPLISVVITTVSLEDLYAKIGARNPHNKQHTISEVLIEVQPIEMVLNLDQITEFM VPICEVLEIIGNSASAQSANKPSAPVPSKITTVQDLPMVHLNSKGIYVYLPLSTGKKS CSVLLLRIESIQLTPSLENPLVRQLVRPDIYQKAAELNMLSTPGALVEDRQYELSVRR VSLSTGNWKQTQEYRIEKTLASKHDNPAFEWNNQSQSTELDHMEIFKDFDFIMIYAPA ISYDRFLVCGQSVEYNCATDFVASLNTHQISLISCIIVRAQRLGCIIDQVCVKNAELP KARSHKTLGNISKYNSVDNSIYFPADPKVFKKDTWIPKSSKKLVSERLSYTNASTSFT DAKGSSDYFYGSCQSDSGIHLGTRMKGYSRSLAAEEINRSGRQPFVLSYPSSVSFVAG IFVLKIYDVLELEELERPVMKPLFLMTVSQPSFMSTQNFKAAVTQASIFNVNISVAKA DVDGKVDSERFNESVFATLPGQLGSSGIPPPLLTIKTQYDRLHQKEVDVELRKPILLR ICENTIKQLASDVFRIYTVLHETPCFNVRSPRPVPEGSQLRQLKMNCYNADRFHLSCD RITAKFYDEERSYKCSFVWLDVSTRIKFSSRPQKAVIRSNIGSFYVQSGEKMLLHPLL MRLSVDLVSEPWSEELLVNATLKLNYLHIDAGVFSILQLQKAQQGVNRIREYADREWQ QFLRSRPVLGTPKDVSPCNLIKCTPSHESIERIKRPLKSNAEFYQDDLRAGAFQFVYL NSESVLPMPYQVQIIKKNYGIICWRYPQPRQMTSIHIYPVPMPVSRPIHIRCRMEYFS ETHETFLHYCDFMLSETSTKQLTPPDRPICATIWRVVILQSLISVDGTCFEGSEDEDL SIEYLQSDFKVDENNDFILHPKVLVGCMRIDTVFRAEKVPKLQLLLCCQDIELNFVNQ TDNTGELPKQLNKYRLRQTPNITQTFLTVHVEDLQMHSRIYSRNDFSLQTEMRARVKC LDYGFLNMLDVLEPMKFSSYVRLTDYPRSLVQANFLVDKLRLNCGPHVIHTLLSSKYH WQEVLQQKDVRHVLMPKLVIVNRIQTPISFGQTNTVEKIPVNPGEVQLYHFRSCSHVQ ELTFFITNPKTLLVDSSDSVHIALKFEDEEKIHNLRVGEYCITLKLAKLSTTQIYILV KGQIELVSMVPFNLVTEFREEEINYDESTPPEHLLLSKERSSYYQNVKRNADINMRLK LTAGLGRGRTGDIPLKTNNNLPWLVKVPTQSAQQFISIWVRILREDIKMDKPAEDFQP QKILICIWPIFEICNMLSCAVKATESTTGESSTIEAMGGRWALNTATTHATEHNIGFT FSGILRGSSKDEYSLMLRTMDWHKFFYYDPTVWTIENALHKLGKSSKRKWPLNDPEEL RVSRVLDFENAFDVKYQTKATREFSCCQGLDVTAWGMFINGTGLYVAIFMIQEQARLD LKANSLQMMPKLKSAFTIDVRFDNGWKSSTPICLEDFTQKSSSNAGRSLYLRYNSFVD IVIVERDEVLRLILEYRQEDDGRRLFKLRSKFVFTNFTDVVLNALTLAMDHKENSTRE EVEAYSICKKARSLVSSESTKNCSGNAMDVFYDLNAHKAKHNCDTAFVYFVCFSVGGS REISIPIPLAVPFTRRCFSLQAGPESIPLMITLIEKDNVHYLNVFRDTAPAIVISNNT NVKFIVAQTSASENSNVSCTNSEFVGRNFEWNQLVLPHSNCYYTPPQMYANFPDVEFT MCNLSLAVYKDKLCAKNKIAWSKPIRTDKSWQKFLHVPHHGDVKVVVCDKHRAIRLNI YYIAQQLEFSVKDLRSRLTKPENVLMPSQEQAAPRPDESSEQENDTKRVTLPNMVTCA HFNEECESKTQTRIKIFIKSFVFSLQTDNRENDFVKTEVCNIYADDSMLIYDDDDDQR ELRLQLPNLQVDNQLYSSGKYDFPVLLCAEKLYRRNCSLPQVYDLDHVYKQQAQRTPV SLFTFIFYQDEMQLQNVRCQIPPFRVYIEDAYLNQLLEALVECEPSNCVYSPPVEQDQ ILLPAGMTLLPDQVVAQSLYISEPLRLNSFTVEPLNLLLSVHTSSRLYIALDHSPLSF SRYERQQILTVPLRFGQSLGLHYLSGAIFGAGWVVGSLEILGSPSGLARSFSTGLRDF VSMPVQGLFRGPWGFLVGVTQGSASLLRNVTAGTVNSVTKLAGSVARNLDRLTLDAEH IELTEARRRARPQGFADGLTQGLTGLGISLLGAVGGLAHHTLEARSSVGVIAGLTKGI VGALTKPISGAAEMLALTGQGVLHTVGFNAMPQQVEPSFIRNVALHGSSNRIWSYLPE ELSRDQMLFFSEIMLQISTQLRPALLFLTSSVLAIMQSDSEDLAFASPISKVDVLADR EDPSKLYLSLKSERRDDFEGQLNYTNERIMKFLNASRLQSIANDSLNDLLQLHELDVD DRIQRQSQCIFYIKPNIGEHLIHYLKVISRIQH" ORIGIN 1 cggggctgaa acgtaaacaa tccaaaattc tatggctatg tttgttttgt taaacatatt 61 cggcccagaa ttgtagcaaa attcacagca tgtaaattca agttaaccgc cggcaacgca 121 ttaaatgaag agtgtcatat aagtgagcag tcaacagcgc tgggatcgag gcctgagcct 181 ccggcgtcgc cacaccatgt tcaaactgga gtcctacatc actccgattc tgctgagcta 241 cgtggccaag tacgtgaaga acttccgcga cgaggatgcc caagtgtcgc tgtgggaagg 301 cgaggtcacc ttccagaatc tggacctgcg cctggaggtg ctcgaggaag agctgaacct 361 cccagtagaa ctagtttccg gccacattca tgaactcagc atcctggtgc cgtggaccaa 421 gcttatgtcc gagcccgtga agatcgtcat caataccata gaattcgtgg ccaagttgcc 481 ggatagtgag agcaagcagc gcagggcctc cttccagcgg gagcagcgaa ggaaatcgaa 541 gcgggagtcc gtggagcagc cggatcagac gaagagtcct ggaccggcaa gctcttccag 601 cgtggtcaac aaaatcatca acaacatcaa cctgcagtgc cacaacatca tcctgaagta 661 tgtggaggac gacatcgtgg tctctatgaa tgtgcagacc cttaacttta gctccgccgg 721 cgaggactgg aagcccacta tggtggacat acacccggtg tccgtcgtca tgcgcaagtt 781 gctccaggtc tcagatttga ccatctgctt ggacaagcgc aacacagctg gtaggataga 841 ggtgtgccag gagccggttc tctaccgatg tactctggag tgccgggttc tccgcaagta 901 caacgccaac acggtgtcca caacaagcac aacacgcatt ggagttttca cgaagtcgct 961 ggatatcaac gtgtcatctc tgcagttccc catggtgatg aggctggtca aaatgctgct 1021 cgagcttaag ccagccgagt ttgaggatga cccccagaat ccagaagatc aggaggcggt 1081 agctgagggc agcgagtcgc aacaggggac cgaatccgca ggacgaagcg tcttttggtg 1141 ggcctggagc ctactgccca gtttcgatac tgaggcgcct tcctcgtcct gcgacactcc 1201 cactggtcac gccttcgatc tgggagtcta cgccgaggag ctgaacttcc agcttaaaaa 1261 ctcggagtac tttaccgacc agagcatggg tggcatcaag cgaatacgat acaccccaat 1321 attgcgaatt agtttgggcg gactttatta cgagcggaca attctaaagg agtgcgactg 1381 ggccaacgtc aaggcgggcc tttctagcat gtgcatggag ccattaggtg cttaccgtag 1441 cgacgatctc gtggatcgca acttggtcaa tacccaggaa tttcagcaag agcgatcctt 1501 tattgacaag agtctgtttg acgagaacta catgttcgcc gaacggtcct ggtgcagcta 1561 caactacgcg gattacgtgg ccaggaacac ggatgaatac atgctgtttc gcagtcctgt 1621 tttggccttc gacgtcatcg agcaccgggt gcctaagccc agcagccatc ccgtggcgga 1681 gagccagctc agagatctgg gagttcgcat ccagtatcgt ctattgtccg ccggaatcac 1741 gttccacttt tcgcagtcgt tcgtccaggt taaaaaggta attagtgatt taattcgtcc 1801 ttacgattac ccgggatatc gttcagaatc gatgaaggat gaggatcgcg gtgtccccga 1861 gccggaaaac aagaactctg aaatgactat acctgatctg gagtatctga tgggattggt 1921 gcccacttgt aactacaaaa ttgagttgcg taacattgtg gttcagttgt atccccgcca 1981 gcagcaagat gagtcatccg cgatcaatca acaccaactg acgaccacag tcagacaatc 2041 tttgctacca tatttgcagc ttaagatctc cctagtcgag ggcacaatgt gtggaccagt 2101 gaatcctgtt cgcctggtcc aactgattac tcatctagaa gagaagcctc gggacgtggt 2161 taatgcctgc tacaactgtt ttcacttcaa tgtgaaaaac ttggcgctta tgattatgaa 2221 tacaactccg gataatggac gtgccaagct tttgaatatt ccacgcgttc aagtgaactg 2281 gaaccgcctt ttggcgcctc atctttggcg tcaaaacgag gcgcctttag agacttcgga 2341 aataaaatca gagatcataa ctttagagtt ctcaaagcgc gagctaatca tcgcaaagcg 2401 cttggtgccg ttaatttcga gtttcagtgg ccaagatctt tgtgatctgg cccacattgt 2461 agccaatgtc aacgtcaatt ctgatgtgat caagctgcag agtgtgggca ccaaactaaa 2521 cctggtctat cacaagtacc atacacattt ggctgcagtg gggtcacttc aaggtgtcca 2581 cactgatgcc gtccatacca aaatgaatat acgcaatgtg gtgttgtcca cttcaaagaa 2641 tgcagacaat aagtggcttg agatgcagtg tcagtttccc ctggaggagg tccattcgga 2701 gcaggaaaaa attcccggca cagtggtgtg cctttggttg gaaccatttc gcatcactac 2761 ggacatatat ttgctgcagt tcctaaattt ttcggacaac agtggaaggc aaattacaaa 2821 agacaaggaa gtagaaactg atttggagtc tgtgaaccag tcggagccac caattacaca 2881 atcggtttcg aattattcca cgatttctgc atctgcgatc gccttcaatg attttcaacc 2941 gcgtcgaatc agcagaaaca atagtcgaaa gatctcggtc cccgaggaga cagttcatct 3001 aagttccgag cgagatgaga ggcacaccca ggcagaacct ttgaccatac cagtggccaa 3061 taagccacaa ccaagtaatt tcgatacaac cgattttgtg aagcggctga caaaaatggt 3121 agtgctggta gagatcgctc aggctaagat tgacgtatgt gaagtaatga tgcgaaaaac 3181 tcctggacat accgatgtgg agtatacttc cattcgcctg ccgcacatga aagtaaaatc 3241 gggcaattgc gaggccatcc aacgaggaaa catcagagga gttattccag ttgcgagtaa 3301 cactgagcta ttgaattggg tcttcgacct aaacgagttt aacgtttgct atcgcagagc 3361 taatgtgacc gagatgatta tagctccagt gaggaccacg ataaccttag ctctgtcttt 3421 caagacatct gataaagttg acggaagtaa aggaaaagag gataagtgtg ctaacacgtg 3481 ctctataaat gtgcatgtgg atatgtctgc cattaacatt tttgcccagc gggtgaaatt 3541 gctacatgag cactgcttga ttatttccaa gatgtacggt tcgctgtgcc cggacgaacc 3601 tgcatccaag tggcagacag gaaaaatgaa acccagactg gaagtgtaca ctgggagtgc 3661 gcaaaactat ccggttatta aggagttcct ggagctagat ccaaacttcg aagcaccgaa 3721 agtaaaaagt gctcccaaaa gctcagttat actattttgc caatggacaa ttccgcgtat 3781 cagttttgaa atggaaaact ccaatgattt caaacacagc aaaatcgtta tgagtcttga 3841 ggacttactc ctgaatatcg acaagcatag tgacttcaac aaaattacca ccaaaataga 3901 aaacttcggc cttaactact atgaggaaaa gcatgaggaa tgggaaaaga tcgacgactt 3961 gcatatcaaa atgctgggag atagcacaaa cttgccattg attagtgtgg tgatcaccac 4021 tgtgagcctt gaggatcttt acgcaaagat tggggcaaga aaccctcaca acaagcagca 4081 cactatctct gaggtcctca tcgaggtgca accgatagaa atggtgctga acctggacca 4141 aattaccgag tttatggtcc caatatgcga ggtccttgaa attattggaa attctgcctc 4201 tgcacagtca gcgaacaaac cgagtgctcc agttccaagc aagatcacaa cagttcaaga 4261 tctaccaatg gtgcatttaa acagcaaggg aatctatgtt tatcttcctc tgtctacagg 4321 caaaaagagt tgcagtgtcc tgctgctaag gattgaaagt attcaactta ctccgagtct 4381 cgaaaatcct ctagttcgtc agcttgtccg accagatatc taccaaaaag cagcagagct 4441 gaacatgctc agcactccgg gagcactggt ggaggaccgc cagtatgagc ttagtgttcg 4501 gagggtatct ctgtccaccg gaaactggaa gcaaactcaa gagtatcgca tagagaagac 4561 tctggcaagc aaacatgaca atcccgcatt cgagtggaac aatcaaagtc aatccaccga 4621 gctggatcat atggaaatat tcaaagactt tgattttatc atgatttacg caccggctat 4681 aagctacgat agatttttgg tttgtggaca gagtgtggag tataattgcg cgaccgattt 4741 tgtggcttcc ttgaacactc accaaatcag tctgattagc tgcatcatag tgcgcgcgca 4801 gcgattgggt tgtataatcg accaggtctg tgttaaaaat gctgagttac caaaagcgag 4861 atcacataaa acgctgggaa acatttccaa atacaacagc gtggacaact cgatatattt 4921 tccagcagat ccaaaagttt ttaagaagga tacttggatc ccaaaatcat ctaaaaagct 4981 ggtcagcgag aggttaagtt acacgaatgc aagcacaagt tttactgatg ccaaaggcag 5041 tagtgactac ttctacggtt cctgccaaag cgattctgga attcatttgg gcactcggat 5101 gaaaggatat tcaagatcgc ttgcagcgga agagattaat cggagtggac gccaaccgtt 5161 tgtcctgagt taccccagta gcgtatcgtt tgtggccggt atattcgttc ttaagatcta 5221 cgacgttttg gagttggaag aactggaaag acctgtcatg aaaccacttt ttttaatgac 5281 tgtatctcag cccagtttca tgtctaccca aaatttcaaa gcagccgtaa cacaagcctc 5341 gatttttaac gtaaacataa gcgtagccaa ggcagatgtt gatggaaaag tagattcgga 5401 acgatttaat gagtcggtat ttgcaacatt acccggacaa ctgggaagct cgggtattcc 5461 gcctccgttg cttactatta agactcaata tgaccgcctc catcagaagg aagtagatgt 5521 ggagcttcgg aaacccatcc ttttaaggat ttgcgaaaac actatcaaac aattggcaag 5581 tgacgttttc cgtatctaca ctgttcttca cgagactccc tgctttaatg tccgtagtcc 5641 gcgtcctgtg cccgaaggat cccaactccg ccagttgaag atgaattgct acaacgcgga 5701 taggtttcac ttgtcatgtg atcgtataac tgccaagttc tacgatgagg aaaggagcta 5761 taaatgcagc ttcgtctggc tggatgtcag cacccgcatc aagtttagta gtcgccctca 5821 gaaggcggtt ataaggtcca acataggatc attctatgtg cagtccggag aaaagatgct 5881 gctccacccg ttgcttatgc gtttgtccgt agatttggtc agtgagccat ggtctgagga 5941 gctattggtc aatgccacac tcaagctaaa ttaccttcac atcgacgcgg gtgttttcag 6001 catattgcaa ctgcaaaagg cacagcaagg agtgaaccgg atacgcgaat atgccgatcg 6061 ggaatggcag cagttcctgc gcagtcgtcc tgttctgggc actccgaaag atgtctcacc 6121 ctgcaatctg attaagtgca ctccctcaca cgaatcgata gagcggatta aacgaccgtt 6181 gaaatcgaac gcggaatttt atcaggatga cctgagagct ggcgccttcc agttcgtgta 6241 tctgaactcc gagtctgtac tgccaatgcc ctaccaggtg cagatcatta agaaaaacta 6301 tggcatcatc tgctggcgat atccgcagcc gcgccagatg acaagcatac acatatatcc 6361 ggttcctatg ccagtaagca gacccataca tatcagatgt cgcatggagt actttagtga 6421 gacgcatgaa actttcctgc attactgcga ttttatgctc tcggagacct ctactaagca 6481 attgactcca ccagatcgtc cgatctgtgc aaccatttgg agggttgtaa tactgcaatc 6541 gttgatatct gtagacggta catgttttga aggaagtgag gatgaagacc tctcgatcga 6601 gtacctccag tcggacttca aagtggacga aaacaatgat tttattttgc atccaaaagt 6661 tcttgtgggt tgcatgcgaa tcgataccgt ttttagggca gaaaaagtgc caaaactgca 6721 gttgttgctc tgctgccagg acatcgaact gaattttgtg aaccagacgg ataacactgg 6781 tgaactgcct aaacaattga acaagtaccg ccttaggcag acccctaata ttacgcaaac 6841 ctttcttact gtgcacgtgg aggatctaca gatgcattcg aggatatatt ccagaaacga 6901 ttttagtttg cagaccgaaa tgcgcgctcg agttaagtgc ttggactatg gattcctaaa 6961 catgctagat gttctagaac caatgaagtt ctcaagctat gtaaggctga ccgactatcc 7021 acgctctcta gtgcaagcta atttcctagt ggataagctt cggttgaact gcggacccca 7081 tgtgatccac actttgctga gttccaaata ccactggcag gaagttttgc agcagaagga 7141 tgtgcggcac gttttgatgc caaagttggt tatagttaac cggatacaga cgcccataag 7201 ctttgggcaa acgaacactg tcgaaaaaat ccccgtcaat cctggtgaag tgcagctcta 7261 tcacttccgc agctgctccc acgtccagga actaaccttc ttcattacaa atcccaaaac 7321 tcttctggtg gattcaagtg attcagtaca tatagcactt aagttcgagg acgaagaaaa 7381 aatccataat ttgcgggtcg gagagtattg tattactctc aagttagcaa aactctccac 7441 cacccaaatt tatattctgg tcaagggaca aatagagttg gttagcatgg ttcccttcaa 7501 tctggtcact gagtttcgcg aggaggaaat aaattacgac gaaagcaccc caccggagca 7561 tctcctcctg tccaaagaaa gatcatccta ctaccaaaat gtcaagcgga acgccgatat 7621 caacatgcgg cttaagctga ccgccggact tggaagagga cgcactggcg acatcccact 7681 gaaaactaac aacaacttgc cttggctggt caaggttcct acgcaatctg ctcagcagtt 7741 tatcagcatt tgggtgcgaa tcttgcgtga ggacattaaa atggataagc ccgccgagga 7801 ctttcagccg cagaagattc tgatctgcat atggccgatc tttgagatat gcaatatgct 7861 cagctgtgcg gtcaaggcta ccgaaagtac taccggggaa agttccacaa tcgaagccat 7921 gggaggcaga tgggcactga acactgctac aacccatgca acggagcata acattggctt 7981 tacattctcg ggtattttgc gaggatcttc aaaagatgaa tattcgctta tgttaaggac 8041 aatggactgg cacaagttct tttattatga tcccacagtg tggaccatcg aaaatgctct 8101 gcataagctt ggcaagtcat cgaagcgcaa atggccactg aacgatcctg aagaattgcg 8161 ggttagccgc gtgctagatt ttgaaaatgc ctttgatgta aagtaccaga ctaaggcgac 8221 gagggagttc tcctgctgcc aaggactgga cgtgactgcc tggggcatgt tcatcaatgg 8281 aacgggctta tatgtagcca tttttatgat ccaagagcag gcgcgccttg atcttaaagc 8341 aaacagtttg caaatgatgc caaaactcaa aagtgctttc acaattgatg tccgatttga 8401 caacgggtgg aaatcctcaa ctccgatctg tttggaagac tttacccaaa aatcgtccag 8461 caacgccggg cgatcattgt atctgcggta caattcattc gtggatatag ttatagtaga 8521 aagggatgaa gtattgcgcc taatactgga atacaggcag gaagacgacg gacgtcgttt 8581 gttcaaattg cgatcaaaat tcgtattcac taattttacg gatgtggtcc ttaatgccct 8641 gacccttgct atggaccaca aggagaactc tacgcgggaa gaagtggagg catattcaat 8701 ttgcaaaaag gcccgcagtc ttgtttcatc cgaatcaacc aagaattgct cgggtaatgc 8761 aatggacgtc ttctacgatc ttaacgccca taaggctaag cataactgtg atacagcatt 8821 cgtctatttc gtttgcttta gtgttggtgg tagtcgggag atctccatac ccattccctt 8881 ggccgtaccc ttcaccagac gctgcttcag cttgcaagcg ggacccgagt ccatcccatt 8941 gatgatcacc ctaatagaga aggataatgt ccactactta aatgtgttcc gggacacagc 9001 acctgccatt gttattagca acaacacgaa tgtcaagttt attgtggccc aaacgagtgc 9061 ttcggagaac agcaatgtga gctgcacaaa ctcggaattt gtgggaagga acttcgagtg 9121 gaatcagctg gtcctgcctc acagcaattg ctattatacc cctccgcaga tgtacgctaa 9181 ctttccagat gtggaattca caatgtgtaa tttatccttg gcagtttaca aagataagct 9241 ttgtgccaag aacaagatcg cttggtcaaa acccattcgc accgacaagt cttggcagaa 9301 attcctacat gtgcctcacc acggcgacgt gaaagtggtt gtctgtgaca agcatcgagc 9361 tatacgactg aacatctact atatagctca gcagctggag ttttcggtta aagacttgcg 9421 atcacgtttg acaaaacccg agaatgtttt gatgccatcg caggagcagg ctgctccgag 9481 accagatgag agctcggagc aagagaacga cactaaaagg gtaactttac cgaatatggt 9541 gacgtgtgcc catttcaacg aagagtgtga aagcaaaacg cagacaagga tcaaaatttt 9601 catcaagagc tttgtgttca gcctgcagac agacaaccgg gaaaatgact tcgtgaagac 9661 ggaggtgtgc aatatctatg ctgatgactc catgcttatc tacgacgacg acgacgatca 9721 gcgagagctg cgattgcagt tgccaaacct tcaggtagat aaccagttgt actccagtgg 9781 aaagtatgat tttcccgtcc tgctttgtgc ggaaaaactg tacagaagga attgtagtct 9841 gccacaggtc tacgatttgg accatgtata taagcaacag gcacaacgaa ctcccgtctc 9901 tctgttcacg ttcattttct accaagatga aatgcaactg cagaatgtgc gatgtcagat 9961 tccacccttc agggtgtaca tcgaagatgc ctacctgaat caactgctgg aagcattggt 10021 agagtgtgaa ccgtccaatt gtgtctatag tccccctgtg gagcaggatc aaattcttct 10081 gccagccggg atgacccttt tgcccgatca agttgtggcc caatcattgt acatatcgga 10141 acccttgcgt cttaatagtt ttacggtaga gcccctgaat ctattgctat ccgtccatac 10201 atcttcgagg ctctatatag cactagatca ctctccccta tccttttcac gctacgagcg 10261 tcagcaaatc cttacagttc ccctccgatt cggacaatct ctaggactgc actacctcag 10321 cggagcgatt ttcggagccg gctgggtcgt tggttcccta gagatactgg gaagtcccag 10381 tgggctggcg cgctcgttca gcaccggtct gcgagacttt gtgtccatgc ccgttcaggg 10441 tctgttccgc ggaccttggg gcttcctcgt gggagtgacg caaggttctg cctctctgct 10501 gcgaaatgtg acagcaggaa ccgtgaattc cgtgaccaaa ctggctggtt cagtggctcg 10561 gaatctcgac cggctgactt tggacgctga gcacatcgaa ctgaccgagg cgaggcgtag 10621 agctcggcca cagggcttcg ccgatggact gacccaaggt ctgactggat tgggcattag 10681 tttacttggc gctgttggcg gattggccca tcacaccctg gaggcacgaa gttccgttgg 10741 tgttatcgct ggtctcacca agggcattgt tggagcacta acgaaaccaa ttagcggagc 10801 agctgaaatg ctagccctca cgggccaggg tgttctgcat acggtgggct ttaatgctat 10861 gccccaacag gttgagccca gtttcattcg aaacgttgcc ctgcatggaa gctccaatcg 10921 catatggagc tatttgcccg aggagttgag ccgcgatcag atgctgttct ttagtgagat 10981 catgctgcag atcagcacgc agttgcgccc agccttgctg tttctaacct cgtcagtatt 11041 ggccatcatg cagtcggata gcgaagacct ggccttcgcc tctcccattt ccaaggtgga 11101 tgtgttggcg gaccgcgaag atccctccaa actgtacttg agtctgaaat ccgagaggag 11161 ggatgacttt gaagggcaac tcaactacac caatgagcgc atcatgaagt tcctgaatgc 11221 ctctcgactt caaagcatcg ccaacgattc gctgaatgat ctgctccagc tacacgaact 11281 ggatgtggac gaccgaatcc agcggcaatc gcagtgcatc ttctacatta agcccaatat 11341 tggtgaacac ctgatccact acctaaaggt aattagtcgg attcaacatt gatagtaaat 11401 atgcatctgt gcgtacgttt cggattagtc caaagtattc ctagaatcct gtgtatttta 11461 tgccaaaaa //