Dbfetch
LOCUS NM_143012 5188 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster CF transmembrane conductance regulator (Cftr), transcript variant A, mRNA. ACCESSION NM_143012 VERSION NM_143012.3 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 5188) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 5188) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 5188) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 5188) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 5188) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 5188) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 5188) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 5188) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 5188) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 5188) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 5188) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 5188) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 5188) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 5188) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 5188) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 5188) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 5188) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 5188) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 5188) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 5188) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 5188) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 5188) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 5188) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 24 (bases 1 to 5188) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jan 16, 2013 this sequence version replaced NM_143012.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..5188 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="3R" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..5188 /gene="Cftr" /locus_tag="Dmel_CG5789" /gene_synonym="CFTR; CG5789; DmCG5789; Dmel\CFTR; Dmel\CG5789; Dme_CG5789" /note="CF transmembrane conductance regulator" /map="96A6-96A7" /db_xref="FLYBASE:FBgn0039207" /db_xref="GeneID:42928" CDS 265..4473 /gene="Cftr" /locus_tag="Dmel_CG5789" /gene_synonym="CFTR; CG5789; DmCG5789; Dmel\CFTR; Dmel\CG5789; Dme_CG5789" /EC_number="7.2.2.-" /note="CG5789 gene product from transcript CG5789-RA; CG5789-PA; Cftr-PA" /codon_start=1 /product="CF transmembrane conductance regulator, isoform A" /protein_id="NP_651269.1" /db_xref="FLYBASE:FBpp0088845" /db_xref="GeneID:42928" /db_xref="FLYBASE:FBgn0039207" /translation="MDSSAKPTRKNPRQHANIISQLIFAWAIPLLYRGSRRGLNTDDL TQCLKEDRSEQLGDRLEDQWFKELERSHRKKQKPHLRNALFRCFLGPTIINGLICFIY IVIKTLIPAVLAQLLIQFQKTPVAQLRNIDVNDISISDSLNRTARAIPNYVLSQAVAN SSGSPGDALFPKSLDKAGPLEPIQPPVEEVDHNATAVRSILDQTVEHMWNDMNSLGAV LVLSTLFCCFLLHHVDLRQRLMGARMRIACCSLIYRKTLRLSMKTAGQTPAGYLINLL SNDVNRLDYGFIFMHWIWIMPLQAMLTCYLIWLNIGIPAIVGVVGLLLKTVPVQTALS KVTSVLRMRIAERTDARVGIMNELVQGIQVIKMYAWEKPFQAVVAEARRSEIKQIRYA SYLRGFYLSTMVFTERSTLYITLAAAALMGQTITADFVFSAASYYNILQLVAAIWYPL AVSFGAEALVSLRRIQDFLMLEGREERTQGLTHKRDQEGGDSRAVTIKDINASWDIEK PQKTLQSINLQIEKGQLCAVIGPVGAGKSSILQLLLGELPVIDGGVFIQGDLSYAAQE PWLFTGSVRNNILFGEEFDRKRYQEVTRCCALSTDFQQLPNGDKTLVGERGASLSGGQ RARISLARAVYKPAQIYLMDDPLSAVDAHVGRHLFDEVIGPRGRLAQLKATRILVTHQ VHFLSEADVIVIVDQGRILRQGTYQELINSDLDFARLLERPKEEEEGENSRNQTSPLS VNSLESDDEDIPFIDGVKDGYQQLRKQSSSVHGSKSLDSTQLDDNVDEDDLAEAQASG GISPRVWYEYFHAGSTLLSFSFMVFVMVMSQVVCSSSDFFANIWTQQEHQRSQGEATF STFECMYIYGALIIAVVIMTTFRGFLFFKICMHASKVLHDRMFACILHATMRFFDTTP SGRILNRFSKDMGAIDELLPRAMMDFIQIALVMFGILIVIGILNPVLVAAMLVVAVVD VLILKLYLRPSQDLKRLEGICRSPVFSHLSASLTGLAIIRSRQLQDVVAKEFDLLQDV HSSVWQLTMAVNTTLGLWLDCVSCIFLTSVTFSFIISSETTYSGNVGLAIAQAMILTG MVQYGVRQVAESLQQMTSVERVLQYTELEQEPALGEKTPPQQWPTRGQVEFRNMSCRY DPNGSPVLRNLNLTIEAGWKVGIVGRTGAGKSSLIGALFRLAHIEGEIFIDGIETGTI SLEILRTRISIIPQDPVLFSATIRYNLDPFERYTDAELWSALEDVELRKAIPGLDYMV TERGGNFSVGQRQLLCLARAILRNNKVLVLDEATANVDPQTDALIQRTIRIKFKQCTV LTVAHRLHTVMDSDRIIVMDAGVAVEFDVPYLLLKKSQGHLRQMVEATGGESEALKKT ASDSHKRMQRERDERDRDQDESQE" ORIGIN 1 tttcattcgg tcccgaactt ttgaaggagg aggtcgttta tggagcacac ggttgcgcat 61 tcgttggtcc gtttgtgcga gtgtgcgtga gtcggcgttt tgtgcttgtg ttcgtactat 121 ttctgcacgt gctgctccgt tgcgaccaat tcgggtgata caataataat aatagagcac 181 agtagtgtga accaatttat gctctgatag cacaagcaga aggagtttct gatctagacg 241 agagctatcc atccatatga tagcatggat agcagtgcaa agccaacgcg gaaaaatccg 301 cgacagcatg caaatattat ttcacaacta atatttgcct gggcgatacc attactatat 361 cgaggttccc gcagaggcct taatacggat gacctgacac aatgtctgaa ggaagatcga 421 tccgagcagt tgggcgaccg tttggaggat caatggttta aggaactaga gcgatctcac 481 cgcaagaaac agaagccgca tctcagaaac gcacttttcc gctgtttcct aggacccacg 541 atcatcaatg gcctcatttg ctttatctac atagtgatca agaccttaat tccagctgtt 601 cttgcacagc tgttgattca gtttcaaaaa actcctgttg cgcaattaag aaatatcgat 661 gtcaatgata tttcaatatc agattccctg aatcgaacag cacgggcaat tccaaactat 721 gtgctgagtc aggctgtcgc caactctagt ggatctccag gggatgcact tttccccaaa 781 tcgctggaca aagcgggtcc actggagccg attcagcctc cagtagagga agtggatcac 841 aatgcaaccg ctgtgcgaag catcttggat cagaccgtcg agcacatgtg gaacgatatg 901 aacagtctgg gcgccgtcct ggttctttcg acgctgttct gctgcttcct gttgcaccac 961 gtcgatctcc gacagcgcct aatgggtgca cggatgcgaa tagcctgctg ctcgctgatc 1021 taccggaaaa ctctacggct ctcgatgaaa acggctggtc agacgccagc tggttaccta 1081 atcaaccttc tttcgaatga tgtgaatcgt ttggactatg gcttcatatt catgcactgg 1141 atctggatta tgccattgca ggcgatgctc acgtgctacc tgatttggct gaacattggc 1201 atcccagcaa ttgtgggtgt agttggactg ctgctaaaaa cggtgcccgt gcagacggcc 1261 ttgagcaagg taacctctgt gctgcggatg agaattgcgg agcgaacgga cgcgagagtg 1321 ggcattatga acgagctggt gcagggcatt caggttataa agatgtacgc ctgggaaaaa 1381 ccgttccagg cggtggtggc cgaagctcgg cgtagcgaga tcaagcagat ccgatatgca 1441 tcttacctgc gtggcttcta cctcagcacc atggtgttca cggagcgatc cactttgtac 1501 atcaccctgg cagcggctgc tttgatgggc caaaccataa ccgcagactt tgtgttctca 1561 gcagccagtt actacaatat cctgcaactg gtggctgcca tttggtatcc actagctgta 1621 agctttggag cggaagcatt ggtttctctg cgtcggattc aggacttcct tatgctcgag 1681 ggacgtgagg agcgcactca aggacttacc cataagcgag atcaggaagg tggagactcc 1741 agagcagtga ccattaagga cattaatgcc agctgggata ttgagaagcc acagaaaacg 1801 ctccaaagca ttaatctgca gatcgagaag ggccaactgt gcgcagttat tggaccggta 1861 ggtgccggaa agagttctat cctccagtta ctgctgggtg aactgcccgt tatcgatgga 1921 ggcgttttta tccagggtga cctctcctat gcagcccagg aaccatggtt atttacggga 1981 tcggtgcgaa ataacatcct tttcggtgaa gagtttgata ggaagcgtta ccaggaggta 2041 acacggtgtt gtgcccttag cacggatttc caacagctgc caaacggaga caaaactctt 2101 gtgggtgagc gtggggcatc cctttccgga ggccaaagag cacgcatcag cttggcccga 2161 gctgtctata agcccgcaca gatttacttg atggatgatc cgctaagtgc tgttgatgcg 2221 cacgtgggca ggcatctctt cgatgaggtg attggaccca gaggacgact ggctcagctg 2281 aaggcgactc gcattctagt gacccaccag gtgcacttcc tgtccgaggc cgacgttatt 2341 gttattgtcg accaaggaag aattttaagg caaggcacct accaggagct gatcaacagt 2401 gatctggact tcgctaggct ccttgagcga cccaaggagg aggaggaagg ggaaaacagt 2461 cgcaatcaaa catccccgct gagtgtcaat tcactggaga gtgacgacga ggacatacct 2521 ttcatcgatg gtgtaaaaga tgggtaccag cagttgagaa aacagagcag ctcggtacat 2581 ggcagcaagt cgttggacag tacccaactg gatgataatg tcgatgagga tgatctggcc 2641 gaggcccaag catctggtgg catttcacca cgcgtttggt acgagtactt ccatgcgggc 2701 agtactcttc tgagcttcag cttcatggtc tttgttatgg tgatgtccca ggtggtgtgc 2761 agtagttccg atttctttgc gaacatctgg acacagcagg agcatcagag gtcgcaggga 2821 gaggccactt tctcaacctt cgagtgcatg tacatatacg gtgctctgat catcgccgtg 2881 gtgatcatga ccacattccg tggcttcctg ttctttaaga tttgcatgca tgcctccaag 2941 gtgctgcacg atcgcatgtt tgcctgcatc ctgcacgcca ccatgagatt ctttgacacc 3001 actccgtctg gaaggattct gaatcgcttc tccaaggata tgggcgccat tgatgagttg 3061 ctgccgcggg ccatgatgga ttttatacag atcgctctgg tgatgtttgg aattctgatt 3121 gttattggta tactgaatcc ggttttggtg gccgccatgt tggtggtagc cgttgtggat 3181 gtgctcatcc tgaagttgta cctgagacct tcgcaggatc tcaagcgatt ggagggcata 3241 tgccgcagtc cggtgttttc ccatctcagt gcttccctta cgggtctggc catcattcga 3301 tcccgccagt tgcaggatgt ggtggccaag gagtttgatt tgctgcagga tgtgcacagt 3361 agcgtgtggc agctgaccat ggcagtgaat acgactttag gcttgtggct ggactgtgtc 3421 agttgcatct tccttacctc tgtcaccttc agcttcatta tctccagtga aaccacttat 3481 agcggcaacg taggcttggc cattgcccag gccatgatcc taaccggaat ggtgcaatat 3541 ggagtgcgac aagtggccga gtccttgcag caaatgacca gcgtggagcg cgtcctgcaa 3601 tacaccgaac tggagcagga gccggcgctg ggcgaaaaaa cgccaccgca gcagtggccc 3661 acacgcggtc aggtggagtt ccgcaatatg agctgtcgtt atgatccaaa tggatcgccg 3721 gtgcttagga acctgaatct caccatcgag gcgggctgga aggttggcat tgtgggacgt 3781 acaggagctg ggaaatcgtc gctaattgga gctctcttcc gattggctca catcgaggga 3841 gagattttta tcgatggcat agagacggga acgatttcat tggaaattct gcgcacccgc 3901 atctcgatta taccccagga tccggtactg ttttccgcta ccatccgcta caatctggac 3961 cccttcgagc ggtataccga cgctgagctg tggagcgctt tggaagatgt ggagctgcgt 4021 aaagccattc ccggtctgga ctacatggta acggagaggg gcggcaattt cagcgtgggc 4081 caacgtcaat tgctctgcct ggccagggcg attctgcgaa acaacaaggt gctggtactg 4141 gatgaggcca cggccaatgt ggatccacaa accgatgccc tgatccagcg caccatacgc 4201 atcaagttca agcagtgcac agtgctcacc gttgcccatc gattgcacac agtcatggat 4261 tcggatcgga ttatagtaat ggatgctggt gtcgccgtgg aattcgatgt gccgtacttg 4321 ctgttgaaga agtcacaggg acatctccgg caaatggtag aggccacagg cggggaatcg 4381 gaagcactga agaagacggc cagtgacagc cacaaaagaa tgcaaagaga acgggacgag 4441 cgagatcgcg atcaggatga gagccaggag tgagaaacgg tggcccaaaa aaatatccat 4501 cggaaatcgc atttaaccaa atctggtgct tataatggct caaggttaca actcttgggc 4561 tcccaatgga agaggaatct tgtccaaaac aaaaaccgta ccaaaatgat tttcttgtgc 4621 acatacacat attatgttat caatgtttca tttccttagt ttagttaagt ttgttaacga 4681 aaagtctaga atgtgtactg ccttatacgt attgtactta gatgtaatct ccaccaggga 4741 ctacgttgta atatttgtcc accaacctat tgtagaccgc cagtgaatcg gatgtttact 4801 tacaacatga caaaagctac ttacattctg gtaccggacc agaactgaaa caccgaggtc 4861 ctcaaaggat cagtgggtta atctactcac tagttagacc atcaaatata tatattgttt 4921 ataaattgtg tacattactg caagtctata ttcatacaac cgaaatattg tacttgaaac 4981 tctagataga aatttaataa ataatcgtcg ggtttattaa aatataaata agtttcacac 5041 aaattggtaa taaaattgta catttaactt attgagtaaa ttttatacaa tctttttcga 5101 tagtcatttt ttgacacaaa attgcaaagt aagtaaaata taaataattg tcataaaatg 5161 gataatataa tctaaaacct aaacaaac //