Dbfetch
LOCUS NM_142645 4420 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster phosphatidylinositol 3-kinase 92E, transcript variant A (Pi3K92E), mRNA. ACCESSION NM_142645 VERSION NM_142645.3 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 4420) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 4420) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 4420) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 4420) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 4420) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 4420) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 4420) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 4420) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 4420) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 4420) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 4420) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 4420) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 4420) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 4420) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 4420) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 4420) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 4420) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 4420) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 4420) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 4420) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 4420) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 4420) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 4420) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 24 (bases 1 to 4420) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jan 16, 2013 this sequence version replaced NM_142645.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..4420 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="3R" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..4420 /gene="Pi3K92E" /locus_tag="Dmel_CG4141" /gene_synonym="anon-92Ed; CG4141; Dmel\CG4141; Dmp110; dp110; dP110; Dp110; DP110; Dp110/PI3K; dp110alpha; dP13K; dPI3K; dPI3K[92E]; dpP110; Dpp110; p110; p120; PI(3)K; PI-3 kinase; PI-3-K; PI3'K; pi3k; pI3K; Pi3k; Pi3K; PI3k; PI3K; PI3K dp110; PI3K-92D; PI3K-92E/Dp110; PI3K-cat; PI3K-dp110; PI3K-Dp110; PI3K-I; Pi3K92D; pi3k92e; pi3k92E; Pi3k92e; Pi3k92E; PI3K92E; Pi3Kp110; Pi3ks; PiK92E; PI[[3]]K; rea; type-1 PI3K" /note="Phosphatidylinositol 3-kinase 92E" /map="92F3-92F3" /db_xref="FLYBASE:FBgn0015279" /db_xref="GeneID:42446" CDS 379..3645 /gene="Pi3K92E" /locus_tag="Dmel_CG4141" /gene_synonym="anon-92Ed; CG4141; Dmel\CG4141; Dmp110; dp110; dP110; Dp110; DP110; Dp110/PI3K; dp110alpha; dP13K; dPI3K; dPI3K[92E]; dpP110; Dpp110; p110; p120; PI(3)K; PI-3 kinase; PI-3-K; PI3'K; pi3k; pI3K; Pi3k; Pi3K; PI3k; PI3K; PI3K dp110; PI3K-92D; PI3K-92E/Dp110; PI3K-cat; PI3K-dp110; PI3K-Dp110; PI3K-I; Pi3K92D; pi3k92e; pi3k92E; Pi3k92e; Pi3k92E; PI3K92E; Pi3Kp110; Pi3ks; PiK92E; PI[[3]]K; rea; type-1 PI3K" /EC_number="2.7.1.137" /EC_number="2.7.1.153" /EC_number="2.7.1.154" /note="CG4141 gene product from transcript CG4141-RA; CG4141-PA; Pi3K92E-PA; phosphatidylinositol-3 kinase; p110 PI3 kinase; phosphotidylinositol 3 kinase; PI3K class I; PI3-kinase; phosphoinositide 3-kinase; phospho-inositol-3 kinase at 92E; PI3Kinase92E; dPI 3-kinase; phosphatidylinositol 3-kinase; insulin-regulated PI3 kinase; class I PI(3)K; PI 3-kinase; phosphoinositide 3 kinase Dp110; Phosphatidylinositol-3-kinase; Phosphoinositide-3 kinase" /codon_start=1 /product="phosphatidylinositol 3-kinase 92E, isoform A" /protein_id="NP_650902.1" /db_xref="FLYBASE:FBpp0083348" /db_xref="GeneID:42446" /db_xref="FLYBASE:FBgn0015279" /translation="MNMMDNRALAYVAHQPKYETPPEEAEPPCMRFSVNLWKNEMLNW VDLICLLPNGFLLELRVNPANTIQVIKVEMVNQAKQMPLGYVIKEACEYQVYGISTFN IEPYTDETKRLSEVQPYFGILSLGERTDTTSFSSDYELTKMVNGMIGTTFDHNRTHGS PEIDDFRLYMTQTCDNIELERSAYTWQQRLLYEHPLRLANSTKMPELIRERHPTRTFL IVVKNENDQSTFTLSVNEQDTPFSLTESTLQKMNRSQMKMNDRTSDYILKVSGRDEYL LGDYPLIQFLYIQEMLSDSAVPNVVLQSVYRLESYINHHNEQAMVTKRPLPKKRTVHL HKSISSLWDMGNYFQLTLHSISNVNFDKTRALKVGVHVCLYHGDKKLCAQRSTDSPNG NFDTFLFNDLVMDFDIQMRNLPRMTRLCIVIFEVTKMSRSKKSSNNKDIALKDVPYNK NPLAWVNTTIFDHKDILRTGRHTLYTWTYADDIQSVEVFHPLGTIEPNPRKEECALVD LTFLSSGTGTVRYPSEEVVLQYAADREQVNRLQRQLAGPEKPIKELKELMANYTGLDK IYEMVDQDRNAIWERRNDILRELPEELSILLHCVYWKERDDVADMWYLLKQWPLISIE RSLELLDYAYPDPAVRRFAIRCLHFLKDEDLLLYLLQLVQAIKHESYLESDLVVFLLE RALRNQRIGHYFFWHLRSEMQTPSMQTRFGLLLEVYLKGCKHHVAPLRKQLHVLEKLK QGSLIAKKGSKEKVKTMLQDFLRDQRNSAVFQNIQNPLNPSFRCSGVTPDRCKVMDSK MRPLWVVFENADVNASDVHIIFKNGDDLRQDMLTLQMLRVMDQLWKRDGMDFRMNIYN CISMEKSLGMIEVVRHAETIANIQKEKGMFSATSPFKKGSLLSWLKEHNKPADKLNKA INEFTLSCAGYCVATYVLGVADRHSDNIMVKRNGQLFHIDFGHILGHFKEKLGVRRER VPFVLTHDFVYVINKGFNDRESKEFCHFQELCERAFLVLRKHGCLILSLFSMMISTGL PELSSEKDLDYLRETLVLDYTEEKAREHFRAKFSEALANSWKTSLNWASHNFSKNNKQ " ORIGIN 1 tcaacaggag tcaccctgtg ttcgttaaca gacgcttaac agcacgatct caacaataca 61 aataaaaaca atttaatatt ccttaatcga acacaaattt gagccgattg cacggtgcgt 121 ttgaaaaata acaataccgc ggaatggccg acagaggcca actgaaggtg ccggtgcaga 181 gaatcaaaga gattggcgtg ctgatttaaa tggaaaactt tgaaaacaac aatctgttga 241 taaggtaacc agcgaaatgc gggacaacta gcctccgtag cctgaaagag gccattgaaa 301 agtctaatta ggaggagctg gtgatcctca agatccgagg caccagatcc aaaatccgaa 361 cttgaagatc aaatagtcat gaacatgatg gacaaccggg cgttggccta cgtggcccac 421 cagcccaagt atgagacacc gccggaagaa gcggagccgc cctgcatgcg cttttcggtt 481 aacctgtgga aaaacgagat gctgaactgg gtggacctaa tctgcctgtt gcccaatgga 541 ttcctgctgg agctcagggt caatccggcc aacaccatcc aggtaatcaa ggtggagatg 601 gtcaaccagg ccaaacagat gccactgggc tatgtgatca aagaggcctg cgagtaccag 661 gtgtacggca tctcgacctt caacatcgaa ccttacaccg acgaaacgaa gcgactcagt 721 gaggtccagc cgtacttcgg catcctcagc ctcggcgagc gcaccgacac aacgagcttt 781 agcagcgact acgagctgac caagatggtt aacggaatga tcggcaccac cttcgatcat 841 aatcgaacgc acggctcgcc cgagattgac gacttccggc tgtatatgac ccaaacttgc 901 gacaacatcg aactggagcg ctccgcctac acctggcagc agagactgct ctacgagcat 961 cctctgcgac tggcgaactc gactaaaatg cccgagctga tacgggagcg gcatccgacc 1021 agaacctttc tcatcgtcgt aaagaacgag aacgaccaga gcacgtttac gttgtcggtg 1081 aacgagcagg acactccctt ctcgctcacg gaaagcacgc tgcagaagat gaatcggtcg 1141 cagatgaaaa tgaacgaccg gacctccgac tacatactca aagtgagcgg tcgcgacgag 1201 tacctgcttg gcgactatcc cctgattcag ttcctgtaca tccaagagat gctctcggac 1261 tcggcggttc caaatgtggt gttgcaatca gtttaccgcc tagagtccta catcaaccac 1321 cacaacgagc aggccatggt aaccaaacga ccgctgccga agaaacggac agtccacctc 1381 cacaagtcga tctcctcgct gtgggacatg ggcaactact ttcagttgac gctgcacagc 1441 atttccaatg tgaactttga caagacgcgt gccctcaagg tgggcgtgca tgtgtgccta 1501 tatcacggcg acaagaagtt atgcgcccag cgatcaacgg actcccctaa cggcaacttt 1561 gacacgttcc tgtttaatga cctggtgatg gactttgaca tacagatgcg caacctaccg 1621 cggatgacac gcctctgcat tgtgatcttc gaggtgacca agatgtcgcg ctcgaagaaa 1681 tcgtccaaca ataaggacat cgctctgaaa gacgtcccgt acaacaaaaa cccgctggcc 1741 tgggtcaaca caacaatttt cgaccacaag gacatcctgc gcaccggtcg ccatacgctg 1801 tacacgtgga cgtatgctga cgacattcag tcggttgagg ttttccatcc gctgggcacc 1861 atcgaaccca atccgcgcaa agaggaatgt gcgctggtgg acctcacatt cctcagcagc 1921 ggaaccggaa cggtgcggta tcccagcgag gaggtcgtgt tgcagtacgc tgcggatcga 1981 gagcaggtca atcgactgca acggcaactg gcagggccag aaaagccgat caaagaactg 2041 aaggagctta tggccaatta tacaggactg gataagatct atgagatggt tgaccaggac 2101 cgcaatgcca tttgggaacg cagaaacgac attttgcgtg agcttccgga agagctgtcc 2161 atcttacttc actgcgtcta ttggaaggag cgtgatgacg tagcggatat gtggtatctt 2221 ctcaaacagt ggccgcttat ttctatagaa cgctccttgg agctactgga ctacgcctat 2281 ccagatccgg cagtgagacg ctttgccatc cggtgcttac actttctgaa agacgaagac 2341 ttgctcctgt atctgctgca attggtacag gccatcaagc acgaatcgta cctggaaagc 2401 gatctggtag tgtttctgct ggagcgggca ctgcgcaacc aacgcatcgg ccactacttc 2461 ttctggcacc tacgctctga gatgcagacg ccgtctatgc aaacacgctt tggcctactg 2521 ctggaggtat acctcaaggg ttgcaaacat cacgtggcgc cgctgcggaa gcagcttcat 2581 gtgctagaga agctgaaaca gggatctctg attgccaaga agggcagcaa ggaaaaggtg 2641 aagaccatgc tgcaggactt tctgcgggac cagcgcaact cggctgtctt tcagaacatc 2701 caaaatccac ttaatcccag cttccggtgc agtggtgtaa ctcccgatag gtgcaaggta 2761 atggatagca agatgcgacc gctatgggtg gtattcgaga atgctgacgt caacgccagc 2821 gatgtgcaca tcattttcaa aaacggtgac gatctccgcc aggacatgct cacgttgcag 2881 atgttgcgtg tgatggacca gctgtggaaa cgcgatggta tggacttccg catgaacatc 2941 tacaactgca tcagcatgga gaagagcctg ggcatgatcg aggtggtgcg ccacgcagaa 3001 accattgcca acatacaaaa ggaaaagggc atgttctccg ccacgtcgcc gttcaagaag 3061 ggctcgcttc tcagttggct caaagagcac aacaagcccg ccgacaaact gaacaaagcc 3121 atcaacgagt tcacgctcag ctgtgcaggc tactgcgtgg ccacctatgt gcttggcgta 3181 gctgatcgac actcggacaa tataatggtc aagcgaaatg gacagctttt tcacatcgat 3241 tttggccaca tcctgggcca cttcaaggaa aagcttggag tacgtcgaga acgagtgccc 3301 tttgtcttga cccacgactt tgtctacgta atcaacaagg gcttcaatga ccgcgagtct 3361 aaagagtttt gtcattttca ggaattgtgc gagcgcgcct ttctagtttt acgcaaacac 3421 ggctgcctta ttctatcgct gttctcaatg atgatttcaa cgggactgcc agaactgtcc 3481 tccgaaaagg atttggacta cctacgggaa actttagtgc tggactacac ggaggaaaaa 3541 gcacgcgaac atttccgagc gaaattcagc gaagctttgg ccaactcctg gaagacttcc 3601 cttaactggg cctcgcacaa cttctccaaa aacaacaaac agtaaacaac agacaactac 3661 atctacatca acaagctgac aacaacaaca cgattgcttc gaagtcagcg acatctcaca 3721 atcaagcaaa cccactcacc aagtctaagt ttctgcctgc ccttccgagc ctctgcaaca 3781 ggcgtagtac aattttgtat ccaattcata aagttcaaaa ctatgtgttc actatgttag 3841 gccgagaact acccaatcga caacccctcg atccatagct gatagtgtcg ctcccacaag 3901 tgctccaata tatacacctt actcttaatt tgtacatttc acgttcaccc attcttgtaa 3961 ctgtaatcat ttatcgcccc gccccctctt atacagtgat ttttgatcct aaaaattgtt 4021 ttgttgtcta ttattcattt gttgtttgaa cacccccccg cacatgcaca ttggcgcatg 4081 aacgtgcaaa aattgtatcc tattatgcta tattaattta agagacatta actctataag 4141 ttaaaattaa cgattttcta tccctacatt acgattaatt gtgtactata atttgtgtgt 4201 gcttttgtac cagcaaccaa tcaacattat cgtgtttccc ggtttcattt tataatgttc 4261 tctaataatt gtaacgtatt ttgtaaatcg ctggataaat acaataaaac gaaagaaatc 4321 aaatatagaa acgaacgaat gtatacaatt aaagcgaaac cagaaaaata tagatatatt 4381 atgtgcttct acgtttacga tagaccgcat tcgtctcaat //