Dbfetch
LOCUS NM_137146 3457 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster knot (kn), transcript variant D, mRNA. ACCESSION NM_137146 VERSION NM_137146.3 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 3457) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 3457) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 3457) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 3457) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 3457) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 3457) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 3457) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 3457) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 3457) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 3457) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 3457) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 3457) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 3457) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 3457) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 3457) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 3457) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 3457) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 3457) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 3457) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 3457) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 3457) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 3457) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 3457) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 24 (bases 1 to 3457) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jul 15, 2014 this sequence version replaced NM_137146.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..3457 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="2R" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..3457 /gene="kn" /locus_tag="Dmel_CG10197" /gene_synonym="CG10197; coe; col; Col; Col/Kn; collier; Collier; DmCOE; Dmel\CG10197; Kn; Kn/Col; Knot" /note="knot" /map="51C2-51C3" /db_xref="FLYBASE:FBgn0001319" /db_xref="GeneID:45318" CDS 518..2188 /gene="kn" /locus_tag="Dmel_CG10197" /gene_synonym="CG10197; coe; col; Col; Col/Kn; collier; Collier; DmCOE; Dmel\CG10197; Kn; Kn/Col; Knot" /note="CG10197 gene product from transcript CG10197-RD; CG10197-PD; kn-PD; Collier-Knot; collier/knot; early B cell factor; colier; KNOT; knotted" /codon_start=1 /product="knot, isoform D" /protein_id="NP_610990.2" /db_xref="FLYBASE:FBpp0290614" /db_xref="GeneID:45318" /db_xref="FLYBASE:FBgn0001319" /translation="MEWGRKLYPSAVSGPRSAGGLMFGLPPTAAVDMNQPRGPMTSLK EEPLGSRWAMQPVVDQSNLGIGRAHFEKQPPSNLRKSNFFHFVIALYDRAGQPIEIER TAFIGFIEKDSESDATKTNNGIQYRLQLLYANGARQEQDIFVRLIDSVTKQAIIYEGQ DKNPEMCRVLLTHEVMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNA GNPRDMRRFQVVISTQVAVDGPLLAISDNMFVHNNSKHGRRAKRLDTTEGTGNTSLSI SGHPLAPDSTYDGLYPPLPVATPCIKAISPSEGWTTGGATVIIVGDNFFDGLQVVFGT MLVWSELITSHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGSPGRFVYVSLNEPTIDYG FQRLQKLIPRHPGDPEKLQKEIILKRAADLVEALYSMPRSPGGSTGFNSYAGQLAVSV QDGSGQWTEDDYQRAQSSSVSPRGGYCSSASTPHSSGGSYGATAASAAVAATANGYAP APNMGTLSSSPGSVFNSTSRVSSLSFNPFALPTCNTQGYSTQLVTSTK" ORIGIN 1 tcagttgggg tttaacagcc actcgggacg gtagcgcgcg ccgctcaaac ttgttgcgag 61 accaattttc cgaaaatccc aaattctcta cggtgcattg gccagttcac ccaaaaacac 121 ccacacacac acacacacag actgtctcac tttcgtttcg cgattgattg ccagctctcc 181 ggagaccaag aaccaaaata atagaaaagg gaacccaata ccaatacgac gccgcaaacc 241 gatcgagtta taaatacaat acgcaaataa aaaactaaac aaacagtaaa acgcctagca 301 aagagccttc aaaacggcag ccacaatttc cagcgcagga ttaggaggag acgtagccgc 361 gtacgctgat ctccaccagc actcgcattc gcaccatccg aatccgcatc cacatccgca 421 tccccatccg ttcgccaccg acggcttcaa gctgcgttcc gaagagccgg tgccgggctt 481 cagctcggcc tccccctggc ccaccctgga gctgggcatg gagtggggcc ggaagctgta 541 ccccagtgcc gtttccggtc cgcgatccgc cggcggcctg atgttcggcc tgccgcccac 601 cgccgctgtg gacatgaacc agccgcgcgg tccgatgacc tcgctgaagg aggagccgct 661 gggcagccgg tgggccatgc agccagtcgt tgaccagagc aatttgggca ttggccgcgc 721 ccactttgaa aagcagccgc ccagcaattt gcgcaagtcg aacttctttc acttcgtgat 781 cgccttatat gatcgggctg gacaaccgat cgaaatcgag cggacggctt tcattggatt 841 catcgagaag gactcggaat cggatgccac caagacgaac aatggcatcc agtaccggct 901 gcagttactc tacgcaaatg gagctcgcca ggagcaggac attttcgtgc gtctcatcga 961 ttcggtgacc aagcaggcca tcatatatga gggtcaggac aagaatcccg agatgtgtcg 1021 agtgctccta acgcacgagg tgatgtgcag ccgctgctgt gataagaaga gctgtggtaa 1081 ccgcaacgag acgccatcgg atcccgtcat tattgatcgc ttcttcctga aattcttctt 1141 gaaatgcaat caaaactgtc tgaaaaacgc tggcaatccg cgggatatgc gccgatttca 1201 ggtggtaatt tctacgcagg tggccgtgga tggaccacta ttggccatct ccgacaacat 1261 gttcgtgcat aacaattcga agcacggacg gagggccaag cggctggaca ccacggaagg 1321 tacaggcaac acatccctgt ccatttccgg tcacccccta gcgcccgaca gtacctacga 1381 tggtctctac ccaccgctgc cagtggccac gccctgcatc aaggcgatct cgcccagcga 1441 aggctggaca accggtggcg ccaccgtgat catagtgggc gacaacttct tcgatggcct 1501 gcaggttgtg ttcggcacca tgctggtctg gagcgagcta attacctcgc atgcgatccg 1561 ggtgcagacc ccgccaaggc acatccccgg cgtggtggag gtgacgctat cctataagag 1621 caaacagttc tgcaagggat cacccggtcg cttcgtctat gtctctctca acgaacccac 1681 aatcgactac ggtttccagc gcctgcagaa gctcattccc cggcatcccg gcgatcccga 1741 gaagctccag aaagagataa tcctcaagag ggctgccgat ctggtcgagg cgctgtactc 1801 catgcccaga tctccgggcg gctcgacggg cttcaattcc tatgccggtc aactggcggt 1861 cagtgtccag gatggctccg gccagtggac cgaggacgat taccaacggg cgcagtcgag 1921 cagcgtgagt ccacgtggtg gctactgcag cagcgcctcc acgccgcaca gctcgggagg 1981 atcctacggt gccacggcgg ccagtgcagc ggtggcagcc acggccaatg gctatgcacc 2041 tgcacccaac atgggcacac tctcctcgtc gcccggcagc gtcttcaatt ccacgtcaag 2101 ggtcagcagc ctgagcttca atcccttcgc cctgcccacc tgcaatacac agggctatag 2161 cacccaactg gtgacgtcaa ccaaataata ttactactaa atgaggctat tggcaggccc 2221 caaatccaat ccaatacacc ccctccatcc cacaggagtc gcagatacca cgccaatcac 2281 aagaagctcg aaagtgcaat aaacaaaaga aaatggttcc aaaattcaaa aatctattaa 2341 tatagttgta cattttttga ttgaatgccg tttttaattt aatttgacta atttaattaa 2401 tttgatttgg taatagattt atagacatac gcatagaata ccatatcaaa gtaatggaaa 2461 acatatgatg aagggaaggc atatcatgca agaacccaaa agttaagaac gggcagaact 2521 aattctaaaa tagcttacat agcatacatt ttgtaaatat ttatcccaaa gtaaataaaa 2581 aatcgtaatt aataatcgga actgtgaata gaggaaatta tacaaaatat atacccatga 2641 tgaacaattc taatacgaat caagatatac caaaacagat acaatttgaa agaacttttg 2701 gacataatta actaaatgct tgtatacgat actttcttgg attaatatcg aaaaaataaa 2761 taaataaata atgaaaggaa agtcttggaa atacactctg ccagtcgaga gaaccgaaat 2821 caaaatgtta tatacctaca tagatataca aaaagccaga tttgcagcat atctacgcgt 2881 aatattacaa caaatttata ccaaactttt ggcaaacata tcgtgcactt agtcctaata 2941 tccaccctaa gcgaacatat ttgtataatg cccatcatat ccacaattca aaattcattt 3001 tgagcgaacc acttacctat atcaacaacc aaatcatcaa attagacata catacatttc 3061 gctattcaag tcagtgtttg ataaactacc gatttgttga ctagaatcta agcctagcat 3121 actatatata tatatatata ggcttaagtt tattgtttat tgctcgattt gtaggagttt 3181 tactgtaatt tgtattcgta ttgtatgata atgtacgctt gcactcctag atctacaaaa 3241 tattgaagag aaaaacgaaa tggctggcta cgcaattggg gagcggccaa tacaagcata 3301 tctctataag aaacgcataa acagcagaac ttagccgcaa aatcgatttg taaattacaa 3361 tacaataatt tataataaca atctagcaac gctctctgtt ttgtaaatct taacaagtta 3421 tttaaataaa atttatttaa aataaacgta atacacc //