Dbfetch
LOCUS NM_135562 3097 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster lonely heart (loh), transcript variant A, mRNA. ACCESSION NM_135562 VERSION NM_135562.4 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 3097) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 3097) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 3097) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 3097) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 3097) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 3097) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 3097) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 3097) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 3097) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 3097) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 3097) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 3097) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 3097) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 3097) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 3097) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (10-NOV-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 3097) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 3097) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 3097) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 3097) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 3097) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 3097) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 22 (bases 1 to 3097) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 3097) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 24 (bases 1 to 3097) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 25 (bases 1 to 3097) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jan 16, 2013 this sequence version replaced NM_135562.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..3097 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="2L" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..3097 /gene="loh" /locus_tag="Dmel_CG6232" /gene_synonym="CG6232; CT19510; Dmel\CG6232; Loh" /note="lonely heart" /map="31E3-31E3" /db_xref="FLYBASE:FBgn0032252" /db_xref="GeneID:34435" CDS 87..2729 /gene="loh" /locus_tag="Dmel_CG6232" /gene_synonym="CG6232; CT19510; Dmel\CG6232; Loh" /note="CG6232 gene product from transcript CG6232-RA; CG6232-PA; loh-PA; lonely heart" /codon_start=1 /product="lonely heart, isoform A" /protein_id="NP_609406.2" /db_xref="FLYBASE:FBpp0079619" /db_xref="GeneID:34435" /db_xref="FLYBASE:FBgn0032252" /translation="MAKLLLIFSILTILATIHDSSFVQADLTTKERIKKHQDWLREHR KPKTKKKISINSYYELANLWHTRKDLSSPKQKPNNKEEYLENETTSKISNKSDEKVLK SSTIISLNATNPSTSTFKSVLETTTLPSVTTKDLFESGNVATTRQTPKVEEVFSSPNP PQEATSSTSKKAKKKVYPYPRWDKWSDWSSCSRSCGGGVKYQVRKCINRNLLTNNQLT SNACVGYFKRYQLCNDVPCDEQSPDFRASQCSAYNDKEFHGHRYRWEPYVKDDAECEL NCMPFGMKSFATLNESVIDGTPCGHPAEYFRSQFWERAVCVDGACKAVQASGEIDGLY AHSGSVSCGGLLCRPVTGIFTRNPLPEHAYIHVTTLPVGASNISITELKNSINLLVLR TSNELAIFNGENTVSESGSYEAVGAVFDYHRIDGAEDSNGVTEWITSIGPIRDSLQLM VFTKSANNTGVKYEYMLPIVSESEENEMSLESSDGLLRSGMEDTSSSSSSRAGRKRIF NWKVIGFSSCTKSCGGGTQTPIIRCIRKNPLRYYSQRRCTHSVKPVLNENLLHCNTQP CPAYWRFDDWGECRCSSSGGLRRREVSCVQELASGLVIHVDKAACMEDQPPMQKQCEC PKNRRRNLSRYRLSGPSESSSNSSQVKRSKIDGSDATAIWLVSDWNQYCSVTCGSGVE YRTVFCDRSKAGEQRCDPSTTPESRRPCEKPACELGDWFTGPWSSCNGDCFDLTRTRE VLCIRSQLITEHSECTPELKPQSVEKCSHEEVEYCAARWHYSDWSECTKPCGGGTQRR SVRCLEYDIKMNALRESTHCRYTNREPIYRNCNVQACAEVPKTEVTPVCADKFSNCQW ASQAKLCSYDYYRDNCCFSCTGGI" ORIGIN 1 tcagtttgga tttgagtacc acgcgatgaa gacgacggct tcaattaatc cagaattagg 61 cgtgcagtga tacacggggc ttagaaatgg cgaagctgtt gttaatattc agtattctta 121 caattctcgc aacgatacac gattctagtt ttgtgcaggc ggatttaaca actaaagagc 181 gaattaagaa acatcaggat tggctcagag agcaccgaaa acctaaaacg aaaaagaaaa 241 tctcaattaa ctcatattat gagctggcaa acttgtggca tacgagaaag gatctatcat 301 cacccaagca aaaaccgaat aataaggagg aatacttgga gaacgagaca actagtaaaa 361 tatccaataa atccgatgaa aaagtattaa agtcatcaac gataatatca ttaaatgcca 421 ccaatccaag tacatcgact ttcaaatccg ttctggaaac cactacatta ccaagtgtga 481 ctaccaagga tctctttgaa agtggcaatg ttgcgaccac aagacagact ccgaaagtcg 541 aggaggtgtt ctcgtctccc aatccaccgc aagaagcaac ttcgtcaact tcaaaaaagg 601 cgaaaaagaa ggtgtatcca tatccacgtt gggacaaatg gagtgactgg agttcctgct 661 cccgaagttg cggtggtggc gttaagtatc aggttaggaa atgcatcaat cgtaacctat 721 tgacgaataa tcagcttacg agtaatgcat gtgtcggtta ctttaaacgc tatcaactgt 781 gcaatgatgt gccatgcgac gaacaatccc cagattttcg ggcctcccaa tgctcggctt 841 acaacgataa agagtttcat ggtcatcgat ataggtggga accttatgtc aaggatgacg 901 ctgaatgcga actgaactgt atgccattcg gaatgaaatc atttgccaca ctaaacgaat 961 ccgtaattga tggaactcca tgtggacatc cagctgaata ttttagatcg caattttggg 1021 agcgcgctgt ttgtgttgat ggagcttgta aggcagtgca agccagtggc gaaatcgatg 1081 gattgtatgc gcacagtgga tccgtgagct gtggtggatt actttgccgg ccagttacgg 1141 gcatctttac cagaaatcct ctgccggaac atgcctatat acatgttacc acattgccag 1201 tgggtgcctc caatatttcg ataactgaac ttaagaatag catcaacttg ctggtcctgc 1261 gcacctccaa tgagctggcc attttcaatg gagagaacac tgtctcggag agcggatcct 1321 acgaagcggt tggtgctgtc ttcgattatc atcgaatcga cggagctgag gacagcaatg 1381 gggtgaccga gtggataacg agtattggac ccattcggga ttcattgcaa cttatggttt 1441 tcaccaagtc agccaataat actggcgtga agtacgagta catgctgccc atagtatccg 1501 agtccgagga gaacgagatg tcgctggaga gcagcgatgg cctgttgaga tccggtatgg 1561 aggacaccag ttcatccagt agctcgcggg cgggacgcaa acgtattttt aattggaaag 1621 taattgggtt cagtagttgc acgaaatcct gtggcggcgg cacgcagaca cccatcatcc 1681 gttgcattcg aaagaatcca ttgcggtatt actcgcagcg acgttgcacg cattccgtga 1741 aaccggtgtt gaacgagaac ctattgcact gcaacacgca accctgtccg gcgtattgga 1801 gatttgacga ttggggcgag tgtcgctgct cgtcgagcgg cggtctgcgt cgcagggagg 1861 ttagctgtgt ccaggaattg gcttccggac tggtcataca cgtcgataag gccgcctgca 1921 tggaggatca gccacccatg cagaaacagt gcgaatgtcc caagaatagg cgacgcaatt 1981 tatcccgata ccgcctgtct ggtccttcgg aatcctcatc gaatagcagc caagtgaaga 2041 ggagcaaaat cgatggcagc gacgccacgg ccatttggtt ggtgtccgat tggaatcagt 2101 attgttcggt cacctgcggt tcgggcgttg agtatcgtac cgtattctgt gatcgctcca 2161 aggccggcga gcagagatgt gatcctagca ccactccgga aagtcgtcgt ccctgcgaga 2221 agcccgcctg cgagttgggt gattggttca ctggtccgtg gtcatcgtgc aatggcgatt 2281 gtttcgacct gacacgcacc cgcgaggtgc tgtgcatccg tagccagctg attacggagc 2341 acagcgagtg tacgccggag ctgaagccgc aatccgttga gaagtgctcc cacgaggagg 2401 tggagtactg cgctgcccgt tggcactact cggattggtc ggagtgtacc aaaccatgtg 2461 gcggtggaac ccagcgacgc agtgtgagat gcttggagta cgacatcaag atgaacgcct 2521 tgcgggaatc aacgcattgt cggtacacca acagggagcc catatatcgc aattgcaatg 2581 tgcaagcgtg tgcagaagtt ccgaaaactg aagtgactcc agtctgtgcg gataagttct 2641 ctaattgcca gtgggcttcg caggcaaagt tatgtagcta cgattattat cgcgataatt 2701 gttgtttttc ctgcacgggt ggcatttaaa gttcgtagtt cgtaagactc ttaattaatt 2761 tataaaacga ttatttaacc gccgtgcaga atagctaaaa aaacaaatat tatcaagctt 2821 taccccacgc atttgacatt ttgttaactc tagaacttag tatttctgac actaaagctc 2881 aaaaaaaaag cttgcaggga aatgcaaaag ttaaaaaata tcgatcgaaa agaatgtatt 2941 aacgcaaatc aataacaaca tactaaagta aactagataa agactaaaac atattattta 3001 gtgaaattat catattctta aacgtaacat taagaaacga gaaacgatgt tgtttcatac 3061 gcaaccatat gaatttcaat aaaacagaga ttaaatg //