Dbfetch
LOCUS NM_135525 8431 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster ubiquitin fusion-degradation 4-like (Ufd4), mRNA. ACCESSION NM_135525 VERSION NM_135525.2 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 8431) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 8431) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 8431) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 8431) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 8431) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 8431) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 8431) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 8431) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 8431) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 8431) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 8431) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 8431) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 8431) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 8431) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 8431) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (10-NOV-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 8431) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 8431) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 8431) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 8431) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 8431) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 8431) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 22 (bases 1 to 8431) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 8431) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 24 (bases 1 to 8431) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 25 (bases 1 to 8431) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jul 15, 2014 this sequence version replaced NM_135525.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..8431 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="2L" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..8431 /gene="Ufd4" /locus_tag="Dmel_CG5604" /gene_synonym="CG5604; Dmel\CG5604; ufd4" /note="Ubiquitin fusion-degradation 4-like" /map="31C4-31C6" /db_xref="FLYBASE:FBgn0032208" /db_xref="GeneID:34378" CDS 194..8377 /gene="Ufd4" /locus_tag="Dmel_CG5604" /gene_synonym="CG5604; Dmel\CG5604; ufd4" /note="CG5604 gene product from transcript CG5604-RA; CG5604-PA; Ufd4-PA" /codon_start=1 /product="ubiquitin fusion-degradation 4-like" /protein_id="NP_609369.1" /db_xref="FLYBASE:FBpp0079663" /db_xref="GeneID:34378" /db_xref="FLYBASE:FBgn0032208" /translation="MGDVDPETLLEWLSMGQGDERDMQLIALEQLCMLLLMSDNVDRC FESCPPRTFLPALCKIFLDELAPENVLEVTARAITYYLDVSAECTRRIVSIDGAIKAI CNHLVVADLSSRTSRDLAEQCIKVLELICTREAGAVFEGGGLNCVLSFIRDCGSQVHK DTLHSAMSVVSRLCTKVEPNTPCIQNCVESLSTLLQHEDPMVSDGALKCFASVADRFT RKWVDPAPLAEYGLTTELLKRLQSVGGNTHSSLTAAGTQPTSSSQPAATTNSDAINEN VAGTATISNSTKVKSSDAAASPQSISTTISLLSTLCRGSPSITHDILRSQLADALERA LQGDERCVLDCMRFADLLLLLLFEGRQALNRGSNNPNQGQLAPRPRRNNTNTDRTHRQ LIDCIRSKDSEALREAIESGGIDVNCMDDVGQTLLNWASAFGTLEMVEYLCEKGADVN KGQRSSSLHYAACFGRPAIAKILLKFGAYPDLRDEDGKTPLDKARERLDDGHREVAAI LQSPGEWMSPDHSLLNKDGKKYTLMEPRGDPEMAPIYLKVLLPIFCRTFLGSMLGSVR RASLALIKKIVQYAYPTVLQSLSETSFSEDAASTSGQNGGNLLIEVIASVLDNEDDGD GHLIVLNIIEEIMCKTQEEFLDHFARLGVFAKVQALMDTDAEELYVQLPGTVEEPAAA QRSSTSVVVAPRPTSDDPMEDAKEILQGKPYHWREWSICRGRDCLYVWSDSVALELSN GSNGWFRFIIDGKLATMYSSGSPENGNDSSENRGEFLEKLMRARSCVIAGVVSQPILP TASALRLVVGNWVLQSQKTNQLQIHNTEGHQVTVLQDDLPGFIFESNRGTKHTFSAET VLGPDFASGWSTAKKKRNKSKTEGQKFQVRNLSREIYNKYFKSAQIIPRGAVAILTDI VKQIELSFEEQHMAPNGNWETTLTDALMKLSQLIHEDGVVSAYEMHSSGLVQALVAVL SVNHWETNSPRCKRNKMQKQRVSVFKKCILEDNVESATNKPRTKSTASILIQKLVSVL ESTEKLPVYLYDSPCTGYSLQILQKRLRFRLERAECESTLFDRSGRTLKMEPLATIGQ LSKYLLKMVAKQWYDLDRSTYFYLKKIREHRTATVFTHSFDFDEEGLLFYIGSNAKTC DWVNPAQYGLVQVTSSEGKTLPYGKLEDILSRDSISLNCHTKDNKKAWFAIDLGVYII PTAYTLRHARGYGRSALRNWLLQGSKDGSTWTTLSTHVDDKSLVEPGSTATWPINCAT DDSVWYRHIRIQQNGRNASGQTHYLSLSGFEIYGRVVGVADDIGKSVKEAEAKTRRER RQIRAQLKHMTTGARVIRGVDWRWEEQDGCAEGTITGEIHNGWIDVKWDHGVRNSYRM GAEGKYDLKLADCEYLSAFDGNQSMGSASTAAKPSEKGGNTLTSRKSSSTPSLPEATE KNQNPEGASNQTVSADNLAWKQTVETIAENVFASAKTQIISNQLAMNTSSSREARAKH KESGTNQMHKDNISGPSPLSRELEHISDLSAINNSMPAINSSNVSDLATISENLSLTE LSKENICRVLTPSYKPAESVTASQSSSHPDVQSSSPRENDIKNISNIEENNKMNANNS VNKISKDLLANLRTSNIAGCPPVTQLSTEALEMIDKMRDGVDMIRNMSNSILSTDTFP VPCTNVPVGGKKTPKAQALINPDNANQKQIIVTSEEFPTKSSKKPSVTLKPAQQPNAV LSIVDIKEQPISNENVSVPSQMSISVPNLTTTSASEVPSTSEVATHTGLLETFAAIAR RRTSQGTNIQDNQIMNAEANVNEHGDQNASGSFLGHSVTSLVKLALSSNFHSGLLSTA QSYPSLSSNNSENIAPSNPSNTSAGQQSASTINHTLTMSLTSTSSDSEQVSLEDFLES CRAPALLGDLDDEDDMDEDNDEEENEDEYEEVGNTLLQVMVSRNLLTFMDDEAMENRL VGVTKRKSWDDEFVLKRQFSALIPAFDPRPGRTNVNQTSDLEISPLGAELPKPQQSGG PETIEQPLLGLKLRGPGIGGIPEVEIDLSNTDWTIFRAVQELLQCSQLNKLDKFRKIW EPTYTIVYREVSPEAQESTCLESEEFPQTPDVSSKSGASTLSPNSPMHIGFNVADNNL CSVDDVLELLTQINGLNQSEIDSDVKEHGVSVLSEDLFISKKITNKLQQQIQDPLVLA SNALPNWCENLNQSCPFLFPFETRQLYFNCTSFGASRSIVCLQSQRDVTVERQRIPIM SPRRDDHEFRIGRLKHERVKVPRNEDLLMWAMQVMKTHCNRKSVLEVEFLDEEGTGLG PTLEFYALVAAEIQRSDLCMWLCDDDLGEDTENSTQSAEGNSKPVGYYVNRREHGIFP APLPQNSEICENVLKYFWFFGVFVAKVLQDMRLVDIPLSTSFLQLLCHNKVLSRNLQK VISDRRNGDLSVVSEDSDIVETCTKLLRTDSNKSNAFGGILSLENLKEIDPTRYQFLQ EMQNLLLRKQSIEFDDTISAEKKHELINELKLQTQNGLEVSLEDLALTFTYLPSSSIY GYTQAELLPNGSSVNVTIDNLEAYCELLMNFILQDGIAQQMKAFSDGFNEVFPLKKLA AFTPSEARMMICGEQFPHWSREDIISYTEPKLGYNKDSPGFQRFVNVLLSMSGDERKA FLQFTTGCSSLPPGGLANLHPRLTVVRKVDAGVGSYPSVNTCVHYLKLPDYPTEEIMK ERLLTATKEKGFHLN" ORIGIN 1 acatgtaatc tctataatca attttcgagc tgtgctgcta gatatttgtg tgaataaaaa 61 tagtgttgtg tattgagtaa ttgttaaaaa gctttaataa gcagctttaa aaaagagtgc 121 aagcattagc aaaatattca atataatgca aaaaagtttt ggtgtagaag cataaatcaa 181 atttcgattt gcgatgggcg atgtcgaccc cgagacgctg ctggaatggt tgtccatggg 241 acaaggagat gagcgggata tgcaactaat cgcactggag cagctgtgta tgctgctcct 301 aatgtccgat aatgtagatc gttgcttcga aagctgccct cctcgaacat ttttaccggc 361 gttgtgtaag atattcctgg acgaacttgc acctgaaaat gtactcgagg tcactgcgcg 421 agccatcacc tattacctgg atgtttcggc tgagtgcacc aggcgtatcg tttccattga 481 tggcgccatc aaagccatat gcaatcatct agtggtcgcc gatctatcat cgcgcacatc 541 tcgcgatctt gccgagcaat gtatcaaagt gctcgagctg atttgcaccc gagaagctgg 601 cgccgtcttc gagggcggcg gcctcaactg cgtactgtcc ttcatacggg actgtggctc 661 gcaggttcac aaggacacct tacactcggc catgtcggtg gtatccaggc tctgcaccaa 721 ggtggaacct aatactccat gcatacaaaa ctgcgtcgag agtctgagca ctctgctgca 781 acacgaggac cccatggtat ccgatggagc tctaaagtgc tttgcctctg tagcagatcg 841 atttacacga aagtgggtgg acccagcacc gttggcagag tacggcctga caaccgagtt 901 gttgaagcgc ctccaaagtg tcggaggaaa cacgcactct tcgctgacag cggctggaac 961 ccagccaacc agctctagcc aacccgctgc aaccacaaac tcggatgcca ttaatgaaaa 1021 cgttgctgga actgcaacca tatccaacag caccaaggtt aagtcatctg atgccgccgc 1081 ctcgccgcaa tcgatatcaa caacgatttc cttgttgtcc acactttgtc gcggatcacc 1141 ctcgattacc catgacattt tgcgatccca attggctgat gccctcgaaa gagctctgca 1201 gggcgatgag cgatgcgtgt tggattgcat gcgatttgcg gatctattgc tgttactatt 1261 gttcgagggt cgccaagcat taaaccgagg aagtaacaac cccaatcagg gacagttggc 1321 gcctcgacca aggcgtaata ataccaacac cgatcgcacg catcgccagc tcattgattg 1381 catacgatca aaggattcgg aagcccttcg tgaggccatc gaatcgggtg gcattgacgt 1441 caattgtatg gacgatgtgg gccaaacact tctcaattgg gcttcggcct tcggtacctt 1501 ggaaatggta gaatatttgt gtgagaaggg agccgatgtc aacaagggtc aacgaagttc 1561 gtccctacac tatgcagctt gttttggtcg cccggctatt gcgaaaatcc ttttgaaatt 1621 cggagcctat ccggatttgc gagatgaaga tgggaaaacg ccattggata aggcgcgaga 1681 aagattagac gatggacatc gagaggtagc ggcaattttg cagtcgcctg gggagtggat 1741 gtcgccagat cattcgcttc tcaacaaaga tggcaaaaag tacacactaa tggagccccg 1801 aggtgatccg gaaatggcgc ccatttacct aaaggtcctt ctgcccatat tctgtagaac 1861 gttcctgggt tcgatgctgg gcagcgtccg gcgggccagt ttggccctga tcaaaaagat 1921 agttcagtac gcgtacccaa cggtgctcca aagtctcagt gaaaccagtt ttagcgaaga 1981 tgcagcgtcg acatcgggtc aaaatggtgg gaacctacta attgaggtga tcgccagtgt 2041 cctagataac gaggatgacg gtgacggtca tttaatagtt ttaaatatta ttgaggaaat 2101 tatgtgtaag acacaggagg aattcctcga tcattttgca aggctaggag tgtttgcaaa 2161 ggtccaagcc ctgatggaca ccgatgcgga ggaattgtat gtacaattac cagggaccgt 2221 agaggaacca gccgcagcgc aaagatcgtc gaccagtgta gtcgttgctc ctaggccaac 2281 atcagatgat cctatggagg acgcgaagga gatattgcaa gggaaaccct atcactggcg 2341 cgagtggagc atttgcagag gccgggattg tttgtacgtc tggtcagatt ctgtggccct 2401 tgagctgtcc aatggctcaa acggatggtt ccgcttcatc atagatggca aactggcaac 2461 gatgtactcc agtggcagtc cggagaacgg aaatgatagt tctgaaaatc ggggcgagtt 2521 tcttgagaaa ctgatgcgtg ctcggtcctg cgtgattgca ggagttgtat cacagcccat 2581 tttgcccact gcgagtgctc tgcgcctagt tgttggcaac tgggttctac agtcgcagaa 2641 aacaaaccag ctacaaattc acaacaccga aggtcatcaa gttaccgtgt tgcaggacga 2701 tttgcccggt tttatttttg aaagcaatcg aggaacgaag cataccttct cggcagaaac 2761 tgtcctgggt cccgattttg catccggttg gtcaacagcc aaaaagaagc gcaacaagtc 2821 aaagacagag ggtcaaaagt tccaggttcg aaacctatcg cgggaaattt ataacaagta 2881 cttcaagtct gcgcaaataa ttcctcgggg cgccgtagcc atacttacgg atatcgtaaa 2941 gcaaattgag ctatcctttg aggagcagca catggcacca aatggaaact gggagaccac 3001 acttacggac gccctaatga agctatctca actgatacac gaagacggcg ttgtaagcgc 3061 ctatgaaatg cattcgtcgg gattggtaca agctttggta gccgtgctgt cggtcaatca 3121 ttgggaaact aattcacctc gctgcaagcg aaacaaaatg caaaagcaac gagtctctgt 3181 attcaagaaa tgtatactgg aggacaacgt tgagtctgca acgaacaaac caagaactaa 3241 aagtactgca agtattttaa ttcaaaaact tgtctcggtt ttggaaagca ccgagaagct 3301 gccagtctat ttgtacgatt ctccatgcac tggatacagt ttgcaaattc tgcagaaaag 3361 acttcgtttc cgtttggagc gtgcagagtg cgaaagcact ttattcgatc gatcgggacg 3421 aactcttaaa atggaaccat tggcaacgat tggacaactt tccaaatatc tactgaaaat 3481 ggtggccaaa caatggtacg acctcgaccg ctcaacatac ttctatttga agaaaattcg 3541 ggagcatagg accgctaccg tgtttacgca ctcctttgat ttcgacgagg aaggcttgtt 3601 attctacatt ggctccaatg ctaagacctg cgattgggtt aacccagcgc aatatggcct 3661 ggtgcaagtg actagctcgg agggcaagac cttaccctat ggcaaactgg aggatattct 3721 atcacgcgat agcatctcac tcaattgtca caccaaggac aacaagaagg cttggtttgc 3781 catagacttg ggtgtctata taattcccac tgcttacacg ctgcgccatg cccgcggtta 3841 tggaagatcg gctttgagaa actggctact tcaaggctcc aaggatggct caacttggac 3901 caccctcagc acacatgtgg atgacaagag tcttgtggag cctggcagca cagccacatg 3961 gcccattaac tgtgcaactg atgattccgt atggtatcgc cacattagaa tccagcaaaa 4021 tggccgcaat gcgtctggcc agacccatta tttgagtttg agtggcttcg aaatctatgg 4081 gcgcgtcgta ggcgttgccg atgatatcgg aaagagtgtc aaggaagctg aggcaaaaac 4141 gaggcgcgag aggcggcaga taagggcaca gctgaagcac atgaccaccg gtgcacgagt 4201 gatccgtggc gtcgattggc gctgggagga acaggacgga tgtgccgagg gcacaataac 4261 cggcgaaata cacaacggct ggatcgatgt gaagtgggac catggtgtgc gcaactccta 4321 tcgcatggga gccgaaggaa aatacgattt gaagttggct gattgcgagt atctatccgc 4381 cttcgacgga aatcagtcga tgggcagtgc aagcacagct gctaaaccaa gtgagaaggg 4441 gggaaacaca ctcacctcac gcaaatcgag ctccactcca tccctgcccg aagccacaga 4501 gaagaatcaa aaccccgagg gtgcgtccaa tcaaactgtt tcggcggaca acttggcctg 4561 gaagcagact gtggagacga ttgcagagaa cgtatttgct tcggccaaga cacagattat 4621 atcaaaccaa cttgctatga acacatcttc ctccagggaa gctcgggcca agcacaagga 4681 gtctggcacc aatcaaatgc ataaggataa cataagtgga ccctcgccat tgagccgaga 4741 gttggagcac atatcggact tgtcggccat caacaactcg atgccggcaa ttaactcgag 4801 caatgtttcc gacctagcca ccatttcgga gaacctatca ctaactgaat tgtccaaaga 4861 gaatatatgc agggtcctaa cgccttccta caaacccgct gagagcgtta ctgcgagtca 4921 gagctcaagt catccggatg tgcagagttc gtcgccgcga gagaacgata tcaaaaacat 4981 atccaacatt gaggaaaaca acaagatgaa cgccaacaac tcggtgaata agatatccaa 5041 ggacctgctc gcaaatctcc gaacctcgaa cattgctggc tgtccaccgg tcacacaact 5101 ttcaaccgaa gccctcgaaa tgatcgacaa aatgcgtgat ggcgtcgaca tgattcgtaa 5161 catgtccaat agcattcttt ccacggacac tttcccagtg ccctgcacaa atgtgccagt 5221 tggcggtaag aagaccccga aggcccaggc tctaataaat ccagataatg ccaatcagaa 5281 gcaaattata gttacatccg aagagtttcc cactaagagt tcaaagaagc ccagtgtaac 5341 cttaaagcca gctcagcaac caaatgctgt cttatccatt gtggacatca aggaacagcc 5401 gatttcgaac gaaaacgttt cggttcccag ccagatgagc atcagtgttc ctaatctgac 5461 aacaacgtcg gcctcggaag ttccctcgac ttccgaagtg gctacccaca ccggtttgct 5521 ggagacattt gccgcgattg ctcgtcgccg tacctcccaa ggtaccaata tacaggataa 5581 tcagatcatg aatgcggaag ccaatgtgaa cgagcacggc gatcagaacg cttcaggctc 5641 attccttggc cactcggtaa ccagtttagt taagttggca ttgtcaagca atttccactc 5701 cggactgctc agcaccgccc aaagttaccc aagcctgtcg tcgaataata gcgaaaacat 5761 agctccgtcg aacccttcaa atacctctgc gggacagcaa tcggcatcaa cgattaatca 5821 taccctaacc atgagtctaa catccacatc gagtgacagt gagcaagtat cgctggaaga 5881 ctttttggag agctgcagag cgccggcgtt gttgggtgac ttggacgatg aggacgacat 5941 ggatgaggac aacgatgaag aggagaatga ggacgagtac gaagaagttg gaaacacact 6001 gttgcaagtg atggtctcac gcaacttgct tacctttatg gatgacgagg cgatggagaa 6061 ccgattggtg ggtgtgacca agcgcaagtc ctgggacgat gagtttgtac taaagaggca 6121 gttctccgcg ttgataccag cattcgatcc acgcccgggc cgcacaaacg tcaatcaaac 6181 gtctgatttg gaaatatccc cccttggcgc cgagctaccg aaaccccagc agagtggtgg 6241 acctgagact atcgaacagc ccttgctggg ccttaaattg cgtggtcctg gaattggtgg 6301 tatacccgaa gtggaaatcg acctgagcaa caccgactgg accatattca gagcggtaca 6361 ggaattactt cagtgcagtc agttgaacaa gctggacaaa ttccgaaaga tatgggagcc 6421 cacatacacc atcgtgtacc gggaggtatc acccgaggcc caggagagca cttgcttgga 6481 atcggaggag ttcccgcaaa cgcccgatgt gtcctccaag agtggtgcat ccactttgtc 6541 ccccaactcg cccatgcaca tcggtttcaa cgtggccgat aataacctgt gctccgttga 6601 cgatgtactc gagctgctca ctcaaatcaa tggtctcaat cagtccgaaa tcgattcgga 6661 tgtcaaggag cacggtgtat cggtgttgtc cgaagatctc ttcatcagca agaaaataac 6721 caacaaactg cagcagcaaa ttcaggatcc attggtgcta gcaagcaacg cgctgccgaa 6781 ttggtgcgag aacctaaacc aatcctgtcc ctttctgttt ccgtttgaga ccaggcagtt 6841 gtacttcaac tgcacatcgt tcggagcatc gcgcagcata gtatgcctac agtcgcagcg 6901 agatgtcacc gtggaacggc agaggatacc catcatgagt ccgcggcggg atgatcacga 6961 attccgcatc gggcgtttaa agcacgaacg cgttaaagtg ccgcgaaacg aggacctgct 7021 catgtgggcc atgcaggtga tgaagactca ctgcaatcga aagtccgtgc tggaggtgga 7081 gtttttggat gaggaaggaa ctggtttggg accaaccttg gagttctacg ccttggtggc 7141 cgcagaaatc cagcgttccg acctctgtat gtggctgtgt gacgatgact tgggcgagga 7201 cacggaaaac tcgacgcaga gtgcggaagg aaactcaaaa ccagttgggt attacgtaaa 7261 tcgcagggag cacggaatat tcccagcccc attaccacag aattctgaga tatgtgagaa 7321 tgtgctcaaa tatttctggt tctttggagt ttttgtggca aaggttttgc aggacatgcg 7381 cctggtggac atacccctat cgacatcatt tctacagctg ctttgtcaca acaaagtgtt 7441 atcacgtaat ctccagaagg tcatttcgga tagacgaaat ggcgaccttt cagtcgtatc 7501 agaagactct gatatagtag aaacctgcac taaattgctg cgaactgatt ccaacaagtc 7561 gaatgcattc gggggtattc tgtcattgga aaacttgaaa gaaatcgatc caactcgtta 7621 tcaattccta caggaaatgc aaaacctatt gttgcgaaag caatcaatcg agtttgacga 7681 tactataagc gcggagaaga aacatgagct tatcaacgag cttaagctgc aaacccaaaa 7741 tggcttggag gtatctttgg aagacctggc ccttacgttc acgtatctgc cgagttcctc 7801 gatctatggt tacacccagg ccgaattgct gcccaatgga tcgtcagtga acgtcaccat 7861 cgacaacctg gaagcgtact gcgaactgct gatgaacttc atcctgcagg acggaatcgc 7921 tcagcaaatg aaggccttca gtgatgggtt caatgaagtg ttccctttga aaaagttggc 7981 cgcttttact ccctcagagg cacgaatgat gatttgtggc gagcagttcc cccattggag 8041 tcgagaagac attatttcat acactgaacc aaaacttggt tacaacaaag acagtcccgg 8101 attccaacgc tttgttaacg ttttgttgag catgtcgggt gacgagagga aggcgttcct 8161 ccaattcaca accggttgca gcagcctgcc gccaggcgga ctggccaacc ttcatccccg 8221 actgacagtt gtccgaaagg tagatgctgg cgttggaagc tatccatccg tgaacacgtg 8281 cgttcactac ttaaagcttc ccgactaccc aaccgaagag atcatgaagg agcgcttgtt 8341 aacagcaacc aaggaaaagg ggtttcattt aaattaaacg atttattgta ctcgatattc 8401 aagttaataa aatttgaacc ttttgttatt t //