Dbfetch
LOCUS NM_133108 13753 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster dorado, transcript variant B (Dora), mRNA. ACCESSION NM_133108 VERSION NM_133108.3 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 13753) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 13753) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 13753) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 13753) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 13753) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 13753) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 13753) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 13753) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 13753) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 13753) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 13753) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 13753) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 13753) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 13753) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 13753) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 13753) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 13753) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 13753) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 13753) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 13753) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 13753) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 13753) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 13753) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jan 16, 2013 this sequence version replaced NM_133108.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..13753 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..13753 /gene="Dora" /locus_tag="Dmel_CG34401" /old_locus_tag="CG17757" /old_locus_tag="CG32542" /old_locus_tag="Dmel_CG17757" /old_locus_tag="Dmel_CG32542" /gene_synonym="CG15037; CG17757; CG32542; CG34401; CG7307; CG7317; Dmel\CG34401; dora; pelado; pldo; Zswim8" /note="Dorado" /map="17F1-17F2" /db_xref="FLYBASE:FBgn0085430" /db_xref="GeneID:50356" CDS 1491..7799 /gene="Dora" /locus_tag="Dmel_CG34401" /old_locus_tag="CG17757" /old_locus_tag="CG32542" /old_locus_tag="Dmel_CG17757" /old_locus_tag="Dmel_CG32542" /gene_synonym="CG15037; CG17757; CG32542; CG34401; CG7307; CG7317; Dmel\CG34401; dora; pelado; pldo; Zswim8" /note="CG34401 gene product from transcript CG34401-RB; CG34401-PB; Dora-PB; pelado" /codon_start=1 /product="dorado, isoform B" /protein_id="NP_573336.3" /db_xref="FLYBASE:FBpp0305363" /db_xref="GeneID:50356" /db_xref="FLYBASE:FBgn0085430" /translation="MDRFSFDDSIRFEEDSLCSWSSEPESLCNNWRGWKKPAAGSGAG NGGLSGMGGMAVAGGSGAPPFGGAGASGSCTPGGNGTAMANTSTCGRHYVSTLAELAA RCVASYIPFELVEHVYPPVPEQLQLRIAFWSFPDNEEDIRLYSCLANSSADEFNRGDS LFRLRAVKDPLQIGFHLSASVVNQTPRAYFNVAVTFDRRRISSCNCTCTSSAYWCSHV VAVCLHRIHCPQEVCLRAPVSESLTRLQRDQLQKFAQYLISELPQQILPTAQRLLDEL LSAQPTAINTVCGAPDPTAGASINDQTSWYLDEKTLHNNIKRILIKFCLPAPIVFSDV NYLTNSAPPAAAEWSSLLRPLRGREPEGMWNLLSIVREMYRRCDRNAVRLLEIITEEC LYCDQILIWWFQTKLALMMGSHGHSGGKHSNTHSNSTALQHACSSLCDEIVALWRLAA LNPGLAPDERDMLHAQFTAWHLKILDRVVKSRMMPSYTNKHQQNSRSETELFIGFKPA IEACYLDWEGYPIPGVTHTHDTNPIYYSPFTCFKHTDLKGESNNPGQLNATQALMSNN KHYNYFSSSSDHGMHAGAFKQRLDRPFRESRFYTNPADLDGGAALAGGGSGRFSTGLG SVAVGGAGAGGLGQMSGGVNNSVGGSAAAEVNPVQQQLPSGSAGVGASVTNAKVVVAT DGNRSSASSEGFCENDDFGGDTSSSHNYCPPGQAVVPGQKSALTESDSQSSFDAVSHQ SKDEPPVGGVGVAVGVEQALSTSDTSSASSSSSSASTASGSSNSSTSSMLMAGQEATV GVGGAVQQTTRRLSKDESFSSSSDEFNQGGVGGSAGRVAMASSGSGSGAGDTVAVGSG STAGGDLTPVPSTSAAARAALAASSTGPVISASPHLAASAAGGLGVLGVGADQPCTSS AHAARALAAAVAASSDKPHVFSNVRPTEDAWDILLARAEGLHAHGHGAEACILAVRLA EQMLANPPNLLLELPPAPKRKGKKQNVNPISHQLTVVASATLSKCAFLCTVLSENSEH YHIGFRICLFALEMPRPPASTKPLEVKLANQEADILALLKRLPLGSAELQVIRERAEQ LRSGTFKTRGEALLPINLATFIFDALVTLSPLGGSTIVPGVASTSGVSSAAGKSMVNT GTRLLLYKHNSDESLGFDAAVAALGLKANVSEAEHPLLCEGTRRQRGDLALTLLSHYK DEPRKIAKIMEKLLDRDIHTLLNAPLLPAYYSSNPPVRTRSNQPTRREDHDYGGGSGC ASSNCNPVANLCELLPADYGSVGGNSRPHSSTSAELELSMCALSMASSGSQSGGVQGM VPTTNAAGTTGTPSSSSTTVSGSQNPNGNPSGSGGGGNGGGGNGGGGGGGGGGGGSTS SRSKESRYKGKRAYPSIPNQPSEASAHFMFELAKNVLTKAGGNSSTSLFTQASTSQNH HGPHRALHMCAFQLGLYALGLHNCVSPNWLSRTYSSHVSWILGQAMEIGAPAISFLID TWEAHLTPPEAAGMADRASRGWDSNMVYPAAELALSVLPHAAALNPNEIQRAILQCKE QSDLMLERACLTVETAAKGGGVYPEVLFQVARYWYELYMRNTPNNSEFEPHDDTMDHS AVSLSALIESQQQHELQQQQQAVQQQQAVQQQQQVVQQQQQVVQQQQQLGMPNSVVPG GVGPGPGLPVAVQPPVVGSVQNPQAQFQPVGVASLAPLGLAQYPPYSFCQGLYAHHHN MSYPPGQMQMFISAGPPPPPQAYGGYQQPPPQQPPNPQQQQQVVQQQVQQQQVVQQQQ QQVQMAGQAPPGHPGQQGHPGQPPSGFQPQPPPGAFQALPPQAYQAMQAGPPGPPMGP PQGYYGPPPPPPPNGPPGVGVGVGVGVGVGVMPMRQHQHQHPVYPFMQQAPPQPPQQQ QPPPSQPPVRQRQPHQFTPTQLRYLLAAYNVGMLAMETLARRVHDDRPQAKYARNPPY GEDVKWLLRISKKLGTQYLHQFCICAVNSIVSPFVLHDVAIESAHYLGRNNHQMVMQH LRSALTPLVQKCQQMYIQCIHQKLYHLTQGDYEEFASIVVAARAAFQITPEGNAQFKD WLQSIKRSKSCKKELWTQINAALQSNSK" ORIGIN 1 acgtttagga gcaaaagagt cgacgatgcg atgggtaaaa acaaagcccc gtgtaaaagt 61 gtccgaaaac cgtgcgtagc atcaaacaaa tcgtaactcg gccagcgaat ctaggtgccg 121 ttgttttcgg ggacgcgtgt gcagtgccgt tttaagtgtc ggtaatcgcc aaaatccaca 181 aaaaatttaa ggatttttta aaaaaacgtt cgctaaacgc atttcgttcg ttcactcaca 241 cacacacgta aacctaacac acgcacagac gcagacaaac acaacgcgca gcgcatatac 301 acacacaaag aaaagaaggc agtgaaaatc gacaagcgca cgcatgcaca cacacactga 361 caagcacgca ggcgaaaaag tgttgatata tatccaatat attgatgttg tgtgcaacgt 421 tgttgttgct gctgctactg ctgtgtgagt gagtgagggc gagcgagaaa gagtgagtgc 481 ggtgcgcgca ggataaagcg aagatgagcc acaaagcgaa ggagtgaaaa aataattaac 541 ggcaaagcgg actgcaaagc gcagagcgga taaaagagga gcgttaacaa caataacaac 601 gactgggggt cccctgcaaa atcaacaaca acagcaagaa ccacatcaac aataataaca 661 gaagcaagaa catcaacaac aagaactaca actacaaatt ggccctctta tttcggcagt 721 cgcatagcat agccccatct cgctctctcg ttcgttgggg gatacgaaaa agttcacatg 781 caacaacaac gacaacaaac aatagcagtc gcagtcgacg cgggcagagg cagcgacaga 841 gaccgcggcg cactgaacgt attttgtaca tataaacaaa aatagttttt aaactcccca 901 aaatctaaat ctaaacctaa agttaagtct aaaagggaaa cttagagccc taagcataaa 961 tctacagtta ataagttaat taaaagcaag cgagtccggc agtgtgcttg agtttgaaag 1021 gggagaaccg aaggagagga acacagcgag agagaaaaga ggaagagaag aacgctcaag 1081 agaaattcgc cttttacacg attttaaatt gagcgtttgg cagagatcca ttatacatat 1141 acatccatcc aaaaagagag gagagtaaca gtgagagaga cggaggaaga ggaagctgag 1201 gaaaacaaac aaacggggga gcagctgaag aagaagaaca agaatcagct tcagcagtag 1261 aaggagcaac tgtaaacaca cacaatctca gcctcacgct ggcgaatcgc aacggcggca 1321 acaacaacag aggaggagga ggcggcggta acaacaacaa caatggagga ggcggaggag 1381 cggctgcagt cggcgctggc gccgaaggag cagcaggagg cggcgcagga gccggagcgg 1441 cgggcagaga cgctgcagga gcagcggcca acgaatggaa tccggaggaa atggaccgct 1501 tcagcttcga cgactccatc cgcttcgagg aagactccct ctgcagctgg agctctgaac 1561 cggaatcgct gtgcaacaac tggcgcggct ggaagaagcc cgctgcaggc agcggcgcag 1621 gcaatggcgg cttgagcggc atgggcggta tggctgtggc cggcggctca ggagcaccgc 1681 cgttcggagg agcaggagcc tctggttcct gcacaccggg cggcaatgga acggccatgg 1741 ccaacacatc cacctgcggc agacattatg tatccacatt ggccgaactg gcagcccgct 1801 gtgtggcctc ctacataccg ttcgagctgg ttgagcacgt gtatccgccg gtgccggagc 1861 agctgcagct gcgcattgcg ttctggagct ttccggacaa cgaggaggac atccggctct 1921 actcctgtct ggccaatagc tcggcggacg agttcaatcg cggcgactcg ttgtttcggt 1981 tgcgagctgt caaggatccg ctgcagatag gctttcacct ctcggccagc gttgtcaatc 2041 agacgccgcg tgcctatttc aatgtggccg tcacctttga ccgccgacgc atctcctctt 2101 gcaactgcac ctgcacctcg tccgcctact ggtgctccca cgtagtcgcc gtttgtctgc 2161 atcgcatcca ttgcccccag gaggtctgtc tgcgtgcccc ggtatcggaa tcattgactc 2221 gcctgcaacg cgaccaattg caaaagtttg cccagtatct gatcagcgag ctgcctcagc 2281 agatcttgcc gacggctcag cggctcctgg atgagttgct cagtgcgcaa cccacggcga 2341 tcaacactgt gtgcggtgca cctgatccca cggctggggc ctcgatcaac gaccagacca 2401 gctggtatct ggacgagaag acgttgcata acaacattaa acgaatcctc atcaagttct 2461 gtttgcccgc cccgattgtg tttagcgacg taaactatct gacgaactcg gctcccccag 2521 cggcggccga atggagctcg ctactccgac cgctgcgggg acgtgagccg gagggcatgt 2581 ggaatctact ttcgatcgta cgcgagatgt acaggcgctg tgatcggaac gcagtgcgtc 2641 tgctggagat catcacggag gagtgcttgt actgcgatca gatactcatc tggtggttcc 2701 agacgaagtt ggcactgatg atggggtccc acggccactc cggcggtaag cattctaaca 2761 ctcactccaa ctccacggca ctgcagcatg cttgcagttc gctgtgcgac gaaatcgtgg 2821 cactgtggcg attggcagcg ctcaatcccg gcctggcgcc ggatgagcga gatatgctgc 2881 acgctcagtt cacggcctgg catctaaaga ttcttgaccg ggtggtcaag agccgaatga 2941 tgccgtcgta caccaacaag caccagcaga actcgcgatc cgagacggag ctgtttatcg 3001 gcttcaagcc ggccatcgag gcgtgctact tggactggga gggctacccc ataccgggag 3061 tgacgcacac ccacgacacg aatcccatct actactcgcc gttcacttgc ttcaagcaca 3121 cggacctcaa gggcgagtct aacaatcccg gccagctgaa tgccacccaa gcgctgatgt 3181 cgaacaacaa gcactacaat tactttagtt catccagcga tcatggcatg cacgcaggag 3241 ccttcaagca gaggttggac cggccttttc gtgagtcgcg attctatacg aatccggccg 3301 atctggacgg aggagcagcg ttggcgggcg gaggatccgg taggttttcc acgggactgg 3361 gctccgttgc cgttggagga gctggtgcag gaggcttggg tcagatgagc ggaggagtta 3421 acaactctgt tggaggatca gcggccgccg aagtgaatcc cgtgcagcag cagcttccca 3481 gtggctcggc gggagtcggt gcctctgtga caaatgccaa ggttgtggta gcaacagatg 3541 gcaatcgttc gagtgccagc agcgagggat tctgcgagaa cgacgatttc ggcggcgaca 3601 ccagcagcag tcacaactac tgtccacctg gacaggcggt tgtgcctggc cagaaatcag 3661 ccctcacgga gtcggattcg cagagcagct tcgatgcagt gtcgcatcag agcaaggatg 3721 agccaccagt cgggggagtg ggtgtggcag tgggtgttga acaagccctt tccacatctg 3781 acacttcgtc ggcctcctcc tcatcgtcat ctgcttctac agcttcaggg agctctaata 3841 gttccacttc ctctatgctt atggctggac aggaggctac tgtcggtgtt ggtggcgctg 3901 tgcagcaaac aactcgtcgc ctcagcaagg atgaatcctt tagtagcagt agcgacgagt 3961 tcaaccaggg aggcgtgggt ggatcagcag gtcgagtggc tatggcctcc agtggaagcg 4021 gatcgggtgc tggcgacaca gtagcggtgg gatcgggatc aacagctggc ggagatctga 4081 cgccggtgcc cagcacgtcg gcagctgccc gtgctgcctt ggccgccagc tcgacagggc 4141 cggtgatttc tgcttcacct catctcgcag ctagcgccgc tggaggctta ggagtgctgg 4201 gtgtgggtgc agaccagcct tgcacctcat ccgcgcatgc agcccgagca ctggcagctg 4261 cagtggctgc ttccagcgat aagccgcatg ttttctccaa tgtccggccc acagaggacg 4321 cctgggatat actgctggcc agagccgagg gtttgcatgc ccacggtcac ggagccgagg 4381 cttgcatcct ggccgtccgt ctggccgaac agatgctggc gaatccgcct aacctacttc 4441 tggaactgcc acccgcaccc aaaagaaagg gcaagaagca aaacgtgaat cccatctcgc 4501 atcagctgac agttgtggcc tctgcaacgc tgtccaagtg cgcttttctg tgcacagtgc 4561 tgtcggagaa ctctgaacac tatcacattg gctttcggat atgcctattc gccttggaga 4621 tgccgcgacc gccagcaagc accaagcccc tggaagtcaa gctggccaac caggaggcgg 4681 acatactggc tctactaaag cgcctgccgc tgggatccgc ggaactgcaa gtaatccgag 4741 agcgagctga gcaactgcgc agcggaacct ttaagacgcg aggagaggct ctattgccta 4801 ttaacctggc cacgtttatt ttcgatgccc tagttacact cagcccctta ggtggatcca 4861 caattgtccc tggcgtggca tccactagtg gtgtatcaag tgcggccggc aagtctatgg 4921 tcaatacagg cacacgtttg ctgctctaca agcacaacag cgatgagagt ctgggattcg 4981 atgctgcagt ggctgctctc ggactaaaag ccaatgtgtc ggaggcagag catccgttgt 5041 tgtgcgaagg aacccgccgg cagcgcgggg atcttgctct gacattgctt tcacactaca 5101 aggatgagcc ccgcaagata gccaagatca tggagaagct tctggacagg gacatacata 5161 cgcttctaaa tgcgccactc ctgcccgctt actactcgag taacccgcct gtgaggacgc 5221 gaagtaatca gcccacgcgt agggaggatc acgattatgg cggtggctct ggatgcgcct 5281 cttccaactg caatccggta gccaatttgt gtgaactttt gccggcggac tacggcagtg 5341 tgggtggaaa cagtcgacca cacagctcca cgagtgccga actggaacta agcatgtgtg 5401 ccctgagcat ggccagcagt ggtagccagt cgggaggcgt tcaaggcatg gtgcccacaa 5461 cgaatgcagc gggaaccacg ggaacaccca gttccagcag cacgacggtc agtgggagcc 5521 agaatcccaa tggtaatccc agtggcagcg gtggaggagg aaatggcgga ggtggtaacg 5581 gaggaggagg aggcggtggc ggtggtggtg gaggctccac cagtagccga agcaaggaaa 5641 gccggtacaa gggaaagaga gcatatccct cgatacccaa ccagccatcg gaagccagtg 5701 cccacttcat gttcgagttg gccaagaatg tgctgaccaa ggccggcggc aatagttcca 5761 catcgctctt cacccaggcg agcacgagcc aaaatcacca tggaccgcac cgtgccctcc 5821 acatgtgcgc cttccaacta gggctgtatg ccctcggtct gcacaactgt gtgagtccca 5881 attggctatc gaggacgtac tcgtcgcacg tctcctggat cctggggcaa gctatggaaa 5941 ttggtgcgcc ggcgataagc tttctgatag acacttggga ggcgcatcta acgcctcccg 6001 aagcagctgg catggccgat cgtgcgtcgc gcggatggga cagcaacatg gtctatccgg 6061 cggcggagct ggctctgtcc gttctgcccc acgcagctgc cctcaatccc aacgagatcc 6121 agcgtgcgat tctgcagtgc aaggagcaaa gcgatctgat gctggagcgg gcctgtctca 6181 ccgtggagac agctgccaag ggcggcggcg tctatccgga ggtgctattc caggtggccc 6241 gctactggta cgagctgtac atgcggaaca cgccgaataa cagcgagttc gagccgcacg 6301 atgacaccat ggaccattcg gccgtgagtc tgagcgccct cattgagtcc cagcagcagc 6361 atgagctcca gcaacaacaa caggcagtgc agcagcaaca ggcggttcag cagcagcagc 6421 aggtggtgca gcaacagcag caagtggtgc agcagcaaca acagcttggc atgcccaatt 6481 ccgtggtgcc aggcggcgtt ggccccggcc ccggactacc cgtagcagtg cagccacccg 6541 tagttggttc tgtccagaat ccacaggccc aattccaacc cgtgggcgtc gcctcactgg 6601 ctcccctcgg actggcgcag tatccaccgt acagcttctg ccagggcttg tatgcgcacc 6661 accacaacat gagctatccg cccgggcaga tgcagatgtt catttcggca gggccgccgc 6721 cgccacctca agcatacggc ggctaccagc agccgccgcc acagcagccg ccgaatccgc 6781 agcaacagca gcaggttgtg caacagcagg tgcagcagca gcaggtggtg caacagcaac 6841 agcagcaggt tcagatggcc gggcaggcgc caccaggtca ccctgggcag caaggacatc 6901 caggtcaacc gccctctggc ttccagccgc aaccaccgcc aggagcattc caggcgctgc 6961 cgccgcaggc ctatcaggca atgcaagcgg gtcccccggg cccgccgatg ggtccgcctc 7021 agggctacta tggtccacca ccaccaccgc ctccgaacgg tccgcctggc gtgggcgtgg 7081 gcgtcggagt cggcgttgga gtgggcgtga tgccaatgcg ccagcatcag caccaacatc 7141 ccgtttaccc attcatgcag caggcgccgc cgcagccacc gcagcagcaa caaccgccgc 7201 cctcgcagcc acccgtgcga caacgacaac cacatcagtt tacacccacc cagctgcgat 7261 atctgctggc tgcctacaat gtgggcatgc tggccatgga aacactggcg cgacgcgttc 7321 acgacgatcg gccgcaggcg aagtatgccc gcaatccgcc gtacggcgag gatgtgaaat 7381 ggttgctacg gatcagcaag aaactgggca cccagtatct gcaccagttc tgcatctgtg 7441 cggtcaactc gatcgtgagt ccgttcgtgc tgcatgacgt ggccattgag tccgcccact 7501 atctgggcag gaacaaccac cagatggtga tgcagcacct gcgttctgcg ctcacgcctc 7561 tcgtccagaa gtgtcagcag atgtacatcc aatgcatcca tcagaagctg tatcatctga 7621 cccagggcga ctatgaggag tttgccagca ttgtagtggc ggcacgcgcc gctttccaga 7681 tcacgccgga ggggaacgcg caattcaagg actggctgca gtctatcaag cgatcgaaat 7741 catgcaaaaa ggagctgtgg acccagatca atgcggccct gcagagcaac tccaaatgac 7801 aaagacttga ctcctgcaat ctgatgacgg cagtggcaac agcaacattg gcgacaacga 7861 cggcggcggc agggacatcg gccacagctg agtgcaagac aacaacggtg gctgcgagta 7921 gcagcagcaa caacagcgct ggtaatcaca acaacatcgg caatagcagc agcagcggcg 7981 tcattaccaa caacaacagc agcagcaacg gcggcaacat caacatcgcc atcagcgact 8041 cagtgaacgg acacaaccat catcatcacc accatcacca caggcatcat catttgctgg 8101 acacgccggc tagcagctct gtgggattag caacagctac agcagcagga ggaggaggga 8161 cagcagcagc aatcccagta gcagccacac cggttagcaa tacaccagca acagcatcgt 8221 catcagcatc agctgcagtt gcagctgcgg ctgcagctgc tgcagcttca gcagcaccaa 8281 gcagcgtggc cagctacgag cgatcggagc gaagaccccc actactggga gcaccacctg 8341 cgctgtccac ggtcagcaat aacaacggcc gatcgggcgc agcgatcgcg tatcactcgc 8401 tgatgccgaa cttttatccc agcacgcggc agctgcacat gcatggccat gcccggggtc 8461 atgcgcaccc accacagcac ggtcaacccc atccccacca gcaaccccag ccacactcgc 8521 atccccacgc gcatccgcat ccgcacccac atccccatca gtaccaactg cagtcgctaa 8581 gccactacca tcagcaactt taacaacgtg tcgctggcac tgcccatggg tacgggctac 8641 cagcggctgg tgcgcctgct gctcctgctg cagcgtcgtc gctttggcgg ccgcaagaac 8701 aaaacggcgg cggcgaacga agtggaagag gagatggacg cgcaactgca gcagccagcg 8761 gtggctgtgc ctgtcggcga tgaggctggg aaccagggaa ccatcgccac ttggctctgg 8821 ctgtggctgt ggctgctagt gttgctggtg ctgctgttgg tcctgggcct gccgctgctt 8881 ttgatgatgc tcctctgatc cgcctccaca tccggagcca gtcccctccc gagaaccacc 8941 gcacttagtt catgttaaac atagttctta tttgtatctt cagttttcgt tagccatttt 9001 ttttttttcg tatttagcta cacttagata cacgatggag acacttttca ggcgtgggtg 9061 tgtgtgtgtg cgtgtgagca ttttagactg agatatctgc caacaacaac aaataccgat 9121 gcccacacac aggcacacac ccacgcataa gaacaacaac aacaacaaca cccacaagca 9181 tggaagttgg aaaagctctg tttgattttt caaaaatgtg ttcagttaaa ctaacgtatt 9241 tatagagatg atctatcaaa tagttttcta caccgacagc tatatgaaaa agaactcgga 9301 cttttacata tatgcttacg atccctagac ctaactttaa ataattttca ctaacatcag 9361 cttcgcaaaa cgtaagaata cccatcttct tctatatata tatatatatt ttgtagtctt 9421 aagtatgagt aaaaaaagaa cggtttatat accatataca tattaatacc ggtggttaag 9481 caatttttta ggattttcaa atttatttga ccaacaacat tcaatatcca acacgaaaac 9541 ccatcgatgc actagaaatt cttcgctgag cagtttattt tgaatgttca actagcaaac 9601 gatctcaact aaagtatcct cacatttcca gttgtgtaga attactacgt ttgaaaaatg 9661 tgggaaaccg cgccacgccc acaaaaagct gaatctgatg gatgtgtatt taggtctata 9721 cagctaaaca atagatagcg aatattcgaa ataaactgcc aggatttctt ttgcttcgac 9781 ctacatatat gtgtccgtct tttccgactt tataacgacc gagcaaagac agatcgaaat 9841 cattatgctc gcacacatgc acacacacac acacacacac acacactttt tatgatatac 9901 aactattgaa agaaaatggt ttttgttggt taatcaaacg agtttagcta aatcatcaga 9961 agaggagttt ctatttttac atttaaaata aacaacaaca aaaaaagaac aaaaaactac 10021 aaaaacaaac taaaaaaata tatattcttt gctttacaaa attgtttata ttttcaaaca 10081 ttttttaatt attttttaat ggtttttata tcgacgcata taaaacattc ttattattaa 10141 accattaata cacaaaagat acaaaaagca aacgaaaaaa aagatcaaac aatttttttt 10201 tattatatac aaacagtgct gttttgaata aatatggttt tttggattta tttcaaaaca 10261 cgcagtgaaa agcgaaaaaa aaaacgaaac aaaaaacaaa aaacaaaaac acacaaaata 10321 atctatgttg gttttatttt tcttggtttt ccttccagat cacataattt gttcacttaa 10381 gctttggttt tcacttctta ctattattca cttcttatta ttattattgt ttagttgatc 10441 ctttcttttg cggttctttg ccacccaatc ccatccatca ttccaatcca acgcaaccga 10501 tcttcagccc aaacaaaagc aaaaaaaaaa agaaaaacta aagcaaactg ccactttcgt 10561 gaggattcga ttcagtaatg ttacatgaat attataaata taactagtta tacacgatcg 10621 cgagcccctg aagattcctc gagtgcaggc ggcctgagct cctcgggatt ccggatcgga 10681 tccctggatt ggtatcgaag cagccggatc ggatcgcttc agttcccgct taaaggttgt 10741 aaatacggac gacgtcttat ataagtattg taactccctt gtgtttttgt ataattacga 10801 gtagagcagc cagaaaccga ttataaagcg aatatataaa tgaaattaca tcgaatccag 10861 accgatttcg atttcgattt cgatttggat ttggatttcg gactcagatt cgaattctga 10921 aagcaatcgc gtaatttgta aacttttagt aggcagtgtt ttatacaaag agcgtagcaa 10981 agaaaatacc gagagcaact taatctattt atataaagta aaacgaacgc aatctgtaaa 11041 ttaaaattaa caacatgttt ttaaattacc atatagttga ctatttccgt gacaaaaaaa 11101 aaaaagaaaa caagaagaaa caaaaaccca atttagaagg aaaggcagac gatttctcgc 11161 tttgttcgcc attaatattt gtaaaataac gataatcccc aattagcaaa accaaacgat 11221 cgaagaacga attgtggaaa atataaaact atagcaacgc aactagcaga caaaggaaga 11281 ccattaaccc attgactcga accactcaat aacaataact gaatagtaaa acgaacaaac 11341 caacaacatt cgatcttaaa taaaaataat aaatgcgaac ataatgttaa cgtagccgat 11401 tagcctttag atcacatata gcgcatattt tacacaagcg tagtgaacca atttccaaac 11461 taaacttaga aactccacga accccaatta cacagatccc caaatcacca actcacctac 11521 accaaagttt tttttttttt gagtcatctg cagtggaata gttttcactt ccaaaaaaaa 11581 taaattattc gatttttaaa ttcaatatcg tgcacgtaca ttaactcctt atttttaatg 11641 gtagaaatcg aatatctgga ctttgcgtag attttgaaga tctgtcccat atcattcaac 11701 tgccactgac attaggttca tcttagaaca atattagcaa gtaatgccga ttccattcga 11761 gattcagttt ccaccaactt ggtcgtagga ctccacgatt cccccacaag acatgcaccc 11821 acaattatcc ttgcgccctg gcgtgtatat agccaagcac tggatcgtcc ggagctggac 11881 gggatgtgga tgcagtgcgg ctatgtcagc tatatagctt gcgaatctgc ttcccgtttg 11941 gatctgcacc acatacataa catatataca aatatagaca actcccatat atatatatat 12001 atagatatat atatatatat atatacatat ttacagatac atattaaaat tgaagcggac 12061 ataaattaat atttaatctt aagtcggaaa taaaacatta cctcatactt taaaaactta 12121 tgaagacagt tacaagtaga acactcgaaa atatatagat tatataccat atacacgata 12181 aatataggcc atttttttgt agcaatcgaa cttaggcttt atgaaattct atcatttgtg 12241 aaacgaatag cagctatgat tttcctgctg tgagagagaa aaccgaggaa aaccgtggaa 12301 atgtgcagtt ttaaggaggg agtgggatta acttccattc cggggattcc cccattggca 12361 cctttctcta ctcatggctc tttgtacatt tttgcactgt aaaaataaaa tattaaaaat 12421 ataaatatat aaattgcttg ctaaaaaagt ttaaacaaaa acgaatggaa aacgcgcaaa 12481 gtttaacata aaatatatac atacacgaag cgacgttatt tatatatacg cctacagaaa 12541 catgcaaaaa actattatat acaaaaaaat atatacatac atatataaat atatatatat 12601 atacaatact tatttacatt gcgtatttta gcgttttatt cgacatcgga aaaaataaaa 12661 ttaaaccaaa aaccaatcgt agaaacgcta caaaagtgtt ctttttaacg aaaacaaaaa 12721 ataaataaaa ataaatacag agagcggaaa atagaatatt aaattaagca acagaaaata 12781 tttatacact gagatgccgc ggcgagttga aagtttgaat ataaaaaaaa aaaacagatt 12841 ggagagcgac aaatttttaa ttgaatttct aattttacaa aagcatacat gttttattta 12901 ccaatcgctg taaatatcaa gcaacacact attctggtgg gctttttttt ttttaatttt 12961 aaactgtctc cactattcgg ccacagcccc cagccacgcc ccctgaaacc aataccacta 13021 caatgcaaag ctttaattca ttgccacaca caacacaatt catagggaca caacacatac 13081 acacccagca aagcaaatgt gctttaaaaa taaaaaatat gtttctctta agtaaactta 13141 aaaacttttt acaaacagac gaaacacaaa gacacagaaa acaagaactc tgccaaaatc 13201 aagctaatac agacgaacaa aagtaaaaac taaatgaaac ccgaaatctt ctctaaaaaa 13261 tagcaacaaa ttgtaaacaa gaatataaca cggaaataac taattataca taaatgatta 13321 aataacgact cgatgagcag aaagaataac aaaaatggaa attaaaaagc ttattttata 13381 tattcaaaca tacaacaata aaaaaaaaac cgaaatgacc attaatgaac taaattataa 13441 acgaaccgag atatagtgta tatgaatgat ttttaacaat gtaaaaattt tgaaccagtc 13501 tctttcgaat tttattcgtt ttcaaatggt ccgaaaagca agaagctgag ttagtgaggg 13561 agagagatag agtgaagaga gggctagagc agcgcattat tattaactaa tttaatatgc 13621 aatatatcta ctatatttaa agaaaaccaa aataatacag atacatgaac gaggaaaatt 13681 aaaatataca ccgcaaggga ggacataaaa tgaacacatt ttaaaacaat gaaaacaaaa 13741 cgaaaaaaat tac //