Dbfetch
LOCUS NM_123902 2042 bp mRNA linear PLN 20-OCT-2022 DEFINITION Arabidopsis thaliana cytochrome P450, family 707, subfamily A, polypeptide 3 (CYP707A3), mRNA. ACCESSION NM_123902 VERSION NM_123902.3 DBLINK BioProject: PRJNA116 BioSample: SAMN03081427 KEYWORDS RefSeq. SOURCE Arabidopsis thaliana (thale cress) ORGANISM Arabidopsis thaliana Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis. REFERENCE 1 (bases 1 to 2042) AUTHORS Tabata,S., Kaneko,T., Nakamura,Y., Kotani,H., Kato,T., Asamizu,E., Miyajima,N., Sasamoto,S., Kimura,T., Hosouchi,T., Kawashima,K., Kohara,M., Matsumoto,M., Matsuno,A., Muraki,A., Nakayama,S., Nakazaki,N., Naruo,K., Okumura,S., Shinpo,S., Takeuchi,C., Wada,T., Watanabe,A., Yamada,M., Yasuda,M., Sato,S., de la Bastide,M., Huang,E., Spiegel,L., Gnoj,L., O'Shaughnessy,A., Preston,R., Habermann,K., Murray,J., Johnson,D., Rohlfing,T., Nelson,J., Stoneking,T., Pepin,K., Spieth,J., Sekhon,M., Armstrong,J., Becker,M., Belter,E., Cordum,H., Cordes,M., Courtney,L., Courtney,W., Dante,M., Du,H., Edwards,J., Fryman,J., Haakensen,B., Lamar,E., Latreille,P., Leonard,S., Meyer,R., Mulvaney,E., Ozersky,P., Riley,A., Strowmatt,C., Wagner-McPherson,C., Wollam,A., Yoakum,M., Bell,M., Dedhia,N., Parnell,L., Shah,R., Rodriguez,M., See,L.H., Vil,D., Baker,J., Kirchoff,K., Toth,K., King,L., Bahret,A., Miller,B., Marra,M., Martienssen,R., McCombie,W.R., Wilson,R.K., Murphy,G., Bancroft,I., Volckaert,G., Wambutt,R., Dusterhoft,A., Stiekema,W., Pohl,T., Entian,K.D., Terryn,N., Hartley,N., Bent,E., Johnson,S., Langham,S.A., McCullagh,B., Robben,J., Grymonprez,B., Zimmermann,W., Ramsperger,U., Wedler,H., Balke,K., Wedler,E., Peters,S., van Staveren,M., Dirkse,W., Mooijman,P., Lankhorst,R.K., Weitzenegger,T., Bothe,G., Rose,M., Hauf,J., Berneiser,S., Hempel,S., Feldpausch,M., Lamberth,S., Villarroel,R., Gielen,J., Ardiles,W., Bents,O., Lemcke,K., Kolesov,G., Mayer,K., Rudd,S., Schoof,H., Schueller,C., Zaccaria,P., Mewes,H.W., Bevan,M. and Fransz,P. CONSRTM Kazusa DNA Research Institute; Cold Spring Harbor and Washington University in St Louis Sequencing Consortium; European Union Arabidopsis Genome Sequencing Consortium TITLE Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana JOURNAL Nature 408 (6814), 823-826 (2000) PUBMED 11130714 REFERENCE 2 (bases 1 to 2042) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 3 (bases 1 to 2042) AUTHORS Krishnakumar,V., Cheng,C.-Y., Chan,A.P., Schobel,S., Kim,M., Ferlanti,E.S., Belyaeva,I., Rosen,B.D., Micklem,G., Miller,J.R., Vaughn,M. and Town,C.D. TITLE Direct Submission JOURNAL Submitted (17-MAY-2016) Plant Genomics, J. Craig Venter Institute, 9704 Medical Center Dr, Rockville, MD 20850, USA REMARK Protein update by submitter REFERENCE 4 (bases 1 to 2042) AUTHORS Swarbreck,D., Lamesch,P., Wilks,C. and Huala,E. CONSRTM TAIR TITLE Direct Submission JOURNAL Submitted (18-FEB-2011) Department of Plant Biology, Carnegie Institution, 260 Panama Street, Stanford, CA, USA COMMENT REVIEWED REFSEQ: This record has been curated by TAIR and Araport. This record is derived from an annotated genomic sequence (NC_003076). On Sep 12, 2016 this sequence version replaced NM_123902.2. FEATURES Location/Qualifiers source 1..2042 /organism="Arabidopsis thaliana" /mol_type="mRNA" /db_xref="taxon:3702" /chromosome="5" /ecotype="Columbia" gene 1..2042 /gene="CYP707A3" /locus_tag="AT5G45340" /gene_synonym="''cytochrome P450; cytochrome P450; family 707; K9E15.12; K9E15_12; polypeptide 3; polypeptide 3''; subfamily A" /note="Encodes a protein with ABA 8'-hydroxylase activity; involved in ABA catabolism. Mutant analyses show that disruption in the gene results in more drought tolerance whereas overexpression results in increased transpiration rate and reduced drought tolerance. Gene involved in postgermination growth. Plant P450 CYP707A3, ABA 8'-hydroxylase, binds enantioselectively (+)-ABA but not (-)-ABA, whereas the enzyme binds both enantiomers of AHI1 (a structural ABA analogue used as ABA 8'-hydroxylase competitive inhibitor)." /db_xref="Araport:AT5G45340" /db_xref="GeneID:834570" /db_xref="TAIR:AT5G45340" CDS 113..1453 /gene="CYP707A3" /locus_tag="AT5G45340" /gene_synonym="''cytochrome P450; cytochrome P450; family 707; K9E15.12; K9E15_12; polypeptide 3; polypeptide 3''; subfamily A" /inference="Similar to RNA sequence, EST:INSD:AI998104.1,INSD:R30318.1,INSD:CB252652.1, INSD:AV544135.1,INSD:BP863194.1,INSD:BP611200.1, INSD:BP617794.1,INSD:EG472347.1,INSD:BP597856.1, INSD:AV552604.1,INSD:BP807119.1,INSD:AV827296.1, INSD:BP608339.1" /note="''cytochrome P450, family 707, subfamily A, polypeptide 3'' (CYP707A3); FUNCTIONS IN: oxygen binding, (+)-abscisic acid 8'-hydroxylase activity; INVOLVED IN: in 8 processes; LOCATED IN: endomembrane system; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group I (InterPro:IPR002401), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 707, subfamily A, polypeptide 1 (TAIR:AT4G19230.2); Has 36434 Blast hits to 36316 proteins in 1856 species: Archae - 82; Bacteria - 8479; Metazoa - 11318; Fungi - 6149; Plants - 8238; Viruses - 6; Other Eukaryotes - 2162 (source: NCBI BLink)." /codon_start=1 /product="cytochrome P450, family 707, subfamily A, polypeptide 3" /protein_id="NP_199347.2" /db_xref="GeneID:834570" /db_xref="TAIR:AT5G45340" /db_xref="Araport:AT5G45340" /translation="MDFSGLFLTLSAAALFLCLLRFIAGVRRSSSTKLPLPPGTMGYP YVGETFQLYSQDPNVFFAAKQRRYGSVFKTHVLGCPCVMISSPEAAKFVLVTKSHLFK PTFPASKERMLGKQAIFFHQGDYHSKLRKLVLRAFMPDAIRNMVPHIESIAQESLNSW DGTQLNTYQEMKTYTFNVALISILGKDEVYYREDLKRCYYILEKGYNSMPINLPGTLF HKAMKARKELAQILANILSKRRQNPSSHTDLLGSFMEDKAGLTDEQIADNIIGVIFAA RDTTASVLTWILKYLADNPTVLEAVTEEQMAIRKDKKEGESLTWEDTKKMPLTYRVIQ ETLRAATILSFTFREAVEDVEYEGYLIPKGWKVLPLFRNIHHNADIFSDPGKFDPSRF EVAPKPNTFMPFGSGIHSCPGNELAKLEISVLIHHLTTKYRLVHLQNDNSPFGN" ORIGIN 1 aaccaattca tctctcccac ttgatttttc atctccaaca caaaaaccaa tccattagag 61 agagaactca caaaacatac ttcgaattcc cattgtttaa aagacgaaga taatggattt 121 ctccggtttg tttctcactc tctccgcggc ggctctgttt ctctgtttac tccgatttat 181 cgccggagtc cgccgtagct cctccacgaa actccctctt cctccgggaa caatgggtta 241 tccttacgtc ggcgaaacat tccaacttta ctcacaagac cctaatgtgt tctttgcagc 301 aaaacagaga agatacggat cggtgttcaa gactcatgta ttgggatgtc catgtgtgat 361 gatctcgagc cctgaagcag cgaaattcgt attggttaca aagtctcatt tgtttaaacc 421 gacttttccg gccagtaaag agaggatgct tggaaaacaa gccatcttct tccatcaagg 481 agattatcat tccaaactta gaaagcttgt tttaagagct ttcatgcctg atgcaatcag 541 aaacatggtc cctcacattg aatcaattgc tcaagaatca ctcaattctt gggatggaac 601 tcaactcaac acttaccagg aaatgaaaac atacactttc aatgttgcgt taatctcaat 661 actcggcaaa gacgaagttt attaccgaga agatctaaaa cgatgctact acattctaga 721 gaaaggttac aattcgatgc cgattaatct tccaggaaca ttattccaca aagccatgaa 781 agctcgcaag gagctagctc aaatcctcgc taacatctta tccaaaagaa gacaaaaccc 841 atcatcacac acagatctcc tcggatcatt catggaagac aaagcaggat taaccgacga 901 acaaatcgcc gataacatca tcggagtaat cttcgccgca agagacacga cggcgagtgt 961 tctgacgtgg atcctcaagt acttagctga taatccaact gttctagaag ctgtcactga 1021 agagcaaatg gcaataagga aagataaaaa agaaggagag agtctcactt gggaagatac 1081 aaagaagatg ccattaactt atagagtaat ccaagagaca ttaagagctg ctacaatctt 1141 atctttcaca tttagagaag ctgtcgaaga tgtcgaatac gaaggatatt tgataccaaa 1201 gggatggaaa gtactgccac tattcagaaa tattcatcac aatgctgata tattttcgga 1261 tccggggaaa ttcgatccgt cgagattcga agttgcgccg aaaccgaata cattcatgcc 1321 ttttggtagt gggattcatt cttgtccagg caatgagtta gctaaacttg aaatctctgt 1381 tctaatccat catctcacca ctaagtacag gttggtacac cttcaaaatg ataatagtcc 1441 ttttgggaat tgacattatt ttgagaagtg ttttctgata aggggtgttt tggtaatttg 1501 cagatggtca atcgtagggc ctagcgatgg aattcagtat gggccgttcg ctcttcctca 1561 gaatggattg cctattgcct tggaacgaaa accatagatg aattacgaga ataccattta 1621 cctttcttaa attagaaagt gaggaatttt ttttcttatt taagaggaaa atctaattct 1681 tttttataat agaaatgaaa agaaagtaga agaaaaaaat cccaagtggg accccccaag 1741 tgtatataag ttttagttta taaaatgtag agaattaaat tttcggagaa aaaagagaat 1801 tagttatata aatgttccat gtgtatgtaa cttggttcat gcctctatat ctttattttt 1861 gtaattttct caaattgtaa attcctttat tacgaatgta atgactgatg gaatgctcat 1921 agagaatttc agaattaatc ttttaacaaa aaaaaataaa aacaattcag cattagtcat 1981 cgttttaagt aacagaacga tatgtttact agactttaac taaaatcaaa cgttgaaatt 2041 tg //