Dbfetch
LOCUS NM_119393 4221 bp mRNA linear PLN 20-OCT-2022 DEFINITION Arabidopsis thaliana cellulose synthase 1 (CESA1), mRNA. ACCESSION NM_119393 VERSION NM_119393.3 DBLINK BioProject: PRJNA116 BioSample: SAMN03081427 KEYWORDS RefSeq. SOURCE Arabidopsis thaliana (thale cress) ORGANISM Arabidopsis thaliana Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis. REFERENCE 1 (bases 1 to 4221) AUTHORS Mayer,K., Schuller,C., Wambutt,R., Murphy,G., Volckaert,G., Pohl,T., Dusterhoft,A., Stiekema,W., Entian,K.D., Terryn,N., Harris,B., Ansorge,W., Brandt,P., Grivell,L., Rieger,M., Weichselgartner,M., de Simone,V., Obermaier,B., Mache,R., Muller,M., Kreis,M., Delseny,M., Puigdomenech,P., Watson,M., Schmidtheini,T., Reichert,B., Portatelle,D., Perez-Alonso,M., Boutry,M., Bancroft,I., Vos,P., Hoheisel,J., Zimmermann,W., Wedler,H., Ridley,P., Langham,S.A., McCullagh,B., Bilham,L., Robben,J., Van der Schueren,J., Grymonprez,B., Chuang,Y.J., Vandenbussche,F., Braeken,M., Weltjens,I., Voet,M., Bastiaens,I., Aert,R., Defoor,E., Weitzenegger,T., Bothe,G., Ramsperger,U., Hilbert,H., Braun,M., Holzer,E., Brandt,A., Peters,S., van Staveren,M., Dirske,W., Mooijman,P., Klein Lankhorst,R., Rose,M., Hauf,J., Kotter,P., Berneiser,S., Hempel,S., Feldpausch,M., Lamberth,S., Van den Daele,H., De Keyser,A., Buysshaert,C., Gielen,J., Villarroel,R., De Clercq,R., Van Montagu,M., Rogers,J., Cronin,A., Quail,M., Bray-Allen,S., Clark,L., Doggett,J., Hall,S., Kay,M., Lennard,N., McLay,K., Mayes,R., Pettett,A., Rajandream,M.A., Lyne,M., Benes,V., Rechmann,S., Borkova,D., Blocker,H., Scharfe,M., Grimm,M., Lohnert,T.H., Dose,S., de Haan,M., Maarse,A., Schafer,M., Muller-Auer,S., Gabel,C., Fuchs,M., Fartmann,B., Granderath,K., Dauner,D., Herzl,A., Neumann,S., Argiriou,A., Vitale,D., Liguori,R., Piravandi,E., Massenet,O., Quigley,F., Clabauld,G., Mundlein,A., Felber,R., Schnabl,S., Hiller,R., Schmidt,W., Lecharny,A., Aubourg,S., Chefdor,F., Cooke,R., Berger,C., Montfort,A., Casacuberta,E., Gibbons,T., Weber,N., Vandenbol,M., Bargues,M., Terol,J., Torres,A., Perez-Perez,A., Purnelle,B., Bent,E., Johnson,S., Tacon,D., Jesse,T., Heijnen,L., Schwarz,S., Scholler,P., Heber,S., Francs,P., Bielke,C., Frishman,D., Haase,D., Lemcke,K., Mewes,H.W., Stocker,S., Zaccaria,P., Bevan,M., Wilson,R.K., de la Bastide,M., Habermann,K., Parnell,L., Dedhia,N., Gnoj,L., Schutz,K., Huang,E., Spiegel,L., Sehkon,M., Murray,J., Sheet,P., Cordes,M., Abu-Threideh,J., Stoneking,T., Kalicki,J., Graves,T., Harmon,G., Edwards,J., Latreille,P., Courtney,L., Cloud,J., Abbott,A., Scott,K., Johnson,D., Minx,P., Bentley,D., Fulton,B., Miller,N., Greco,T., Kemp,K., Kramer,J., Fulton,L., Mardis,E., Dante,M., Pepin,K., Hillier,L., Nelson,J., Spieth,J., Ryan,E., Andrews,S., Geisel,C., Layman,D., Du,H., Ali,J., Berghoff,A., Jones,K., Drone,K., Cotton,M., Joshu,C., Antonoiu,B., Zidanic,M., Strong,C., Sun,H., Lamar,B., Yordan,C., Ma,P., Zhong,J., Preston,R., Vil,D., Shekher,M., Matero,A., Shah,R., Swaby,I.K., O'Shaughnessy,A., Rodriguez,M., Hoffmann,J., Till,S., Granat,S., Shohdy,N., Hasegawa,A., Hameed,A., Lodhi,M., Johnson,A., Chen,E., Marra,M., Martienssen,R. and McCombie,W.R. TITLE Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana JOURNAL Nature 402 (6763), 769-777 (1999) PUBMED 10617198 REFERENCE 2 (bases 1 to 4221) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 3 (bases 1 to 4221) AUTHORS Krishnakumar,V., Cheng,C.-Y., Chan,A.P., Schobel,S., Kim,M., Ferlanti,E.S., Belyaeva,I., Rosen,B.D., Micklem,G., Miller,J.R., Vaughn,M. and Town,C.D. TITLE Direct Submission JOURNAL Submitted (17-MAY-2016) Plant Genomics, J. Craig Venter Institute, 9704 Medical Center Dr, Rockville, MD 20850, USA REMARK Protein update by submitter REFERENCE 4 (bases 1 to 4221) AUTHORS Swarbreck,D., Lamesch,P., Wilks,C. and Huala,E. CONSRTM TAIR TITLE Direct Submission JOURNAL Submitted (18-FEB-2011) Department of Plant Biology, Carnegie Institution, 260 Panama Street, Stanford, CA, USA COMMENT REVIEWED REFSEQ: This record has been curated by TAIR and Araport. This record is derived from an annotated genomic sequence (NC_003075). On Sep 12, 2016 this sequence version replaced NM_119393.2. FEATURES Location/Qualifiers source 1..4221 /organism="Arabidopsis thaliana" /mol_type="mRNA" /db_xref="taxon:3702" /chromosome="4" /ecotype="Columbia" gene 1..4221 /gene="CESA1" /locus_tag="AT4G32410" /gene_synonym="anisotropy1; ANY1; AtCESA1; cellulose synthase 1; CELLULOSE SYNTHASE 1; F8B4.110; F8B4_110; RADIALLY SWOLLEN 1; RSW1" /note="Encodes a cellulose synthase isomer. CESA1 mutants have cellulose defect in the primary cell wall. Multiple lines of evidence suggest that CESA1, along with CESA3 and CESA6 are present in the same plasma membrane complex for cellulose biosynthesis. lasma membrane complex for cellulose biosynthesis. As inferred from the null role of secondary wall-type CesAs, included in a set of five primary wall-type CesAs that may support trichome cell wall thickening." /db_xref="Araport:AT4G32410" /db_xref="GeneID:829376" /db_xref="TAIR:AT4G32410" CDS 457..3702 /gene="CESA1" /locus_tag="AT4G32410" /gene_synonym="anisotropy1; ANY1; AtCESA1; cellulose synthase 1; CELLULOSE SYNTHASE 1; F8B4.110; F8B4_110; RADIALLY SWOLLEN 1; RSW1" /inference="Similar to RNA sequence, EST:INSD:EL166913.1,INSD:EL082639.1,INSD:AV529187.1, INSD:BP591612.1,INSD:EH838977.1,INSD:AV817728.1, INSD:AV528526.1,INSD:EL167909.1,INSD:BP607520.1, INSD:EG522555.1,INSD:EL217035.1,INSD:EH847908.1, INSD:ES148318.1,INSD:BP670328.1,INSD:BP604262.1, INSD:AV546085.1,INSD:T20516.1,INSD:EH934381.1, INSD:AV816310.1,INSD:EL208173.1,INSD:EH862564.1, INSD:AV546317.1,INSD:EG445845.1,INSD:EH956240.1, INSD:AV547247.1,INSD:EL118120.1,INSD:AV546312.1, INSD:DR275791.1,INSD:AV545907.1,INSD:BP621215.1, INSD:CB260305.1,INSD:EL133907.1,INSD:AV548702.1, INSD:AV546311.1,INSD:T20782.1,INSD:EL211398.1, INSD:BP791328.1,INSD:N96792.1,INSD:AV795504.1, INSD:BP786210.1,INSD:BP645762.1,INSD:AV801633.1, INSD:CB260282.1,INSD:AV552905.1,INSD:EL235457.1, INSD:EL009280.1,INSD:EH897694.1,INSD:BP620180.1, INSD:BP602545.1,INSD:DR275793.1,INSD:BE521782.1, INSD:EL038137.1,INSD:AV556404.1,INSD:EG522500.1, INSD:W43507.1,INSD:AV799053.1,INSD:BP794862.1, INSD:BP619693.1,INSD:AV805254.1,INSD:EH986110.1, INSD:AV547629.1,INSD:EL333675.1,INSD:BP606323.1, INSD:AV523011.1,INSD:BP620189.1,INSD:AV534843.1, INSD:AV523139.1,INSD:BP659902.1,INSD:ES081605.1, INSD:AV802203.1,INSD:AV548374.1,INSD:BP664661.1, INSD:AI995716.1,INSD:BP586391.1,INSD:AV566698.1, INSD:AV818168.1,INSD:AV805835.1,INSD:BP640849.1, INSD:AA586282.1,INSD:AV831915.1,INSD:AV544576.1, INSD:EH941754.1,INSD:EG522522.1,INSD:AV554954.1, INSD:AV545922.1,INSD:AV442267.1,INSD:EH878596.1, INSD:AV791449.1,INSD:EL192572.1,INSD:BP608625.1, INSD:EL179365.1,INSD:EG522533.1,INSD:EH864788.1, INSD:BP613073.1,INSD:BP612153.1,INSD:EL166382.1, INSD:EH802392.1,INSD:AA042462.1,INSD:W43615.1, INSD:BP615997.1,INSD:EH878858.1,INSD:EL291729.1, INSD:AV548717.1,INSD:DR275796.1,INSD:BP598872.1, INSD:EL061183.1,INSD:EG522544.1,INSD:BP643407.1, INSD:AV816728.1,INSD:AV798766.1,INSD:EL328984.1, INSD:BP793935.1,INSD:CF651830.1,INSD:BP598867.1, INSD:AV522969.1,INSD:EL335651.1,INSD:AV794366.1, INSD:BP811572.1,INSD:EL314287.1,INSD:EG487182.1, INSD:AV523497.1,INSD:AV828507.1,INSD:BP603762.1, INSD:BP837495.1,INSD:EH964568.1,INSD:BP805130.1, INSD:BP809171.1,INSD:BP831231.1,INSD:BP615975.1, INSD:BP810531.1,INSD:BP844058.1,INSD:EH938926.1, INSD:EH907169.1,INSD:AA394457.1,INSD:DR357350.1, INSD:ES089019.1,INSD:ES016132.1,INSD:EL263305.1, INSD:AV795013.1,INSD:AV812360.1,INSD:BP611412.1, INSD:AV801127.1,INSD:BP581479.1,INSD:BP661871.1, INSD:BP613899.1,INSD:BP832279.1,INSD:EH900037.1, INSD:BP608510.1,INSD:AV538027.1,INSD:EL031725.1, INSD:EL334683.1,INSD:AV807206.1,INSD:CK120272.1, INSD:EH883152.1,INSD:T46527.1,INSD:BP620086.1, INSD:EL338533.1,INSD:AV797315.1,INSD:BP801949.1, INSD:AV530468.1,INSD:DR275795.1,INSD:AV519670.1, INSD:EH876846.1,INSD:ES165403.1,INSD:AV528856.1, INSD:BP621057.1,INSD:EH860688.1,INSD:EH805709.1, INSD:DR275797.1,INSD:EL285699.1,INSD:EL025426.1, INSD:AV828340.1,INSD:CB261308.1,INSD:BP812591.1, INSD:EH828124.1,INSD:ES148456.1,INSD:AV806728.1, INSD:BP608492.1,INSD:BP808084.1,INSD:AV804064.1, INSD:EL237491.1,INSD:AV552509.1,INSD:BP789160.1, INSD:AV801674.1,INSD:DR275792.1,INSD:AV810101.1, INSD:AV546309.1,INSD:AA042132.1,INSD:EL202600.1, INSD:EH801464.1,INSD:AV545969.1,INSD:EL219994.1, INSD:AV528580.1,INSD:EH879311.1,INSD:EH858475.1, INSD:EL019035.1,INSD:EL275961.1,INSD:EL258500.1, INSD:EH901706.1,INSD:BP783578.1,INSD:BP800056.1, INSD:AV816108.1,INSD:EL253406.1,INSD:EL242200.1, INSD:EL220329.1,INSD:BP806292.1,INSD:AV798070.1, INSD:BP798882.1,INSD:EL114351.1,INSD:EL270597.1, INSD:EL192640.1,INSD:CK121679.1,INSD:BP620095.1, INSD:BP598870.1,INSD:AV523221.1,INSD:EL112974.1, INSD:BP806132.1,INSD:EL028926.1,INSD:DR275788.1, INSD:BP791300.1,INSD:EH981226.1,INSD:AV560817.1, INSD:AV529339.1,INSD:EH916542.1,INSD:EL181678.1, INSD:AV808832.1,INSD:EL323624.1,INSD:AV803524.1, INSD:BP607200.1,INSD:BP619939.1,INSD:BP601314.1, INSD:AV544042.1,INSD:ES156629.1,INSD:BP781692.1, INSD:EH846125.1,INSD:EH825993.1,INSD:AV831459.1, INSD:DR359472.1,INSD:BP604914.1,INSD:EL202776.1, INSD:AV530113.1,INSD:BP629673.1,INSD:EG487183.1, INSD:BP602570.1,INSD:BP577443.1,INSD:EH955807.1, INSD:EL056697.1,INSD:AV548631.1,INSD:DR275789.1, INSD:AV550172.1,INSD:BP669023.1,INSD:AV537459.1, INSD:BP602529.1,INSD:AV548105.1,INSD:BP790721.1, INSD:EH838488.1,INSD:EH842603.1,INSD:EL067339.1, INSD:AV529627.1,INSD:EL313055.1,INSD:AV811327.1, INSD:AV810307.1,INSD:DR275794.1,INSD:BP602704.1, INSD:EL109650.1,INSD:AV803831.1,INSD:T45311.1, INSD:BP824749.1,INSD:CD534481.1,INSD:AV562949.1, INSD:BP617241.1,INSD:EH879904.1,INSD:EH811424.1, INSD:BP641805.1,INSD:EH951974.1,INSD:AV560770.1, INSD:AV554955.1,INSD:BP819896.1,INSD:EH850466.1, INSD:EH809137.1,INSD:EH799880.1,INSD:BP602343.1, INSD:EH845520.1,INSD:AV808694.1,INSD:ES072138.1, INSD:BP620602.1,INSD:BP606883.1,INSD:ES040676.1, INSD:ES211617.1,INSD:EL992305.1,INSD:AV782576.1, INSD:BP653265.1,INSD:EH873794.1,INSD:CB255846.1, INSD:EL181432.1,INSD:BP608218.1,INSD:BP610223.1, INSD:AV522336.1,INSD:BE521783.1,INSD:EL154469.1, INSD:EL240918.1,INSD:EL182590.1,INSD:EL115566.1, INSD:AV810624.1,INSD:AV821981.1,INSD:BP785170.1, INSD:BP599384.1,INSD:EL334288.1" /inference="Similar to RNA sequence, mRNA:INSD:AK226243.1,INSD:BT008654.1,INSD:AK222115.1, INSD:BX827280.1,INSD:BX829135.1" /note="cellulose synthase 1 (CESA1); FUNCTIONS IN: cellulose synthase activity, transferase activity, transferring glycosyl groups; INVOLVED IN: primary cell wall biogenesis, cellulose biosynthetic process, plant-type cell wall biogenesis, hyperosmotic salinity response; LOCATED IN: Golgi apparatus, plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Cellulose synthase (InterPro:IPR005150), Zinc finger, RING-type (InterPro:IPR001841); BEST Arabidopsis thaliana protein match is: cellulose synthase 10 (TAIR:AT2G25540.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink)." /codon_start=1 /product="cellulose synthase 1" /protein_id="NP_194967.1" /db_xref="GeneID:829376" /db_xref="TAIR:AT4G32410" /db_xref="Araport:AT4G32410" /translation="MEASAGLVAGSYRRNELVRIRHESDGGTKPLKNMNGQICQICGD DVGLAETGDVFVACNECAFPVCRPCYEYERKDGTQCCPQCKTRFRRHRGSPRVEGDED EDDVDDIENEFNYAQGANKARHQRHGEEFSSSSRHESQPIPLLTHGHTVSGEIRTPDT QSVRTTSGPLGPSDRNAISSPYIDPRQPVPVRIVDPSKDLNSYGLGNVDWKERVEGWK LKQEKNMLQMTGKYHEGKGGEIEGTGSNGEELQMADDTRLPMSRVVPIPSSRLTPYRV VIILRLIILCFFLQYRTTHPVKNAYPLWLTSVICEIWFAFSWLLDQFPKWYPINRETY LDRLAIRYDRDGEPSQLVPVDVFVSTVDPLKEPPLVTANTVLSILSVDYPVDKVACYV SDDGSAMLTFESLSETAEFAKKWVPFCKKFNIEPRAPEFYFAQKIDYLKDKIQPSFVK ERRAMKREYEEFKVRINALVAKAQKIPEEGWTMQDGTPWPGNNTRDHPGMIQVFLGHS GGLDTDGNELPRLIYVSREKRPGFQHHKKAGAMNALIRVSAVLTNGAYLLNVDCDHYF NNSKAIKEAMCFMMDPAIGKKCCYVQFPQRFDGIDLHDRYANRNIVFFDINMKGLDGI QGPVYVGTGCCFNRQALYGYDPVLTEEDLEPNIIVKSCCGSRKKGKSSKKYNYEKRRG INRSDSNAPLFNMEDIDEGFEGYDDERSILMSQRSVEKRFGQSPVFIAATFMEQGGIP PTTNPATLLKEAIHVISCGYEDKTEWGKEIGWIYGSVTEDILTGFKMHARGWISIYCN PPRPAFKGSAPINLSDRLNQVLRWALGSIEILLSRHCPIWYGYHGRLRLLERIAYINT IVYPITSIPLIAYCILPAFCLITDRFIIPEISNYASIWFILLFISIAVTGILELRWSG VSIEDWWRNEQFWVIGGTSAHLFAVFQGLLKVLAGIDTNFTVTSKATDEDGDFAELYI FKWTALLIPPTTVLLVNLIGIVAGVSYAVNSGYQSWGPLFGKLFFALWVIAHLYPFLK GLLGRQNRTPTIVIVWSVLLASIFSLLWVRINPFVDANPNANNFNGKGGVF" ORIGIN 1 ttttaatata atcaaacaat catactttgt cctatctctt tcttgcaata agattttgcc 61 acgtcacata ctaagaagct ggcgcgtcta gtggggaagc cagaacggct cactttaaaa 121 agtagagaga tgataacttg agccgaatag agccgagctg agctaaaacg gtgggagagg 181 aagaggctac tactaccgtc accatctccg gtaaaataat gtacttgtca tttaaaaatt 241 aagaaaaaac acatcactct gcgataaaat aggcaaaagc agatttgaag aagaagcagc 301 ttgagatatc aaatagagag agagagtgac agaggagtgt gtgaacatcc ttttttagta 361 gatttgggtt ttcgagatgc cgtattgaat cggctacgaa tttcccaatt ttgaattttg 421 tgaatctctc tctttctctg tgtgtcggtg gctgcgatgg aggccagtgc cggcttggtt 481 gctggatcct accggagaaa cgagctcgtt cggatccgac atgaatctga tggcgggacc 541 aaacctttga agaatatgaa tggccagata tgtcagatct gtggtgatga tgttggactc 601 gctgaaactg gagatgtctt tgtcgcgtgt aatgaatgtg ccttccctgt gtgtcggcct 661 tgctatgagt acgagaggaa agatggaact cagtgttgcc ctcaatgcaa gactagattc 721 agacgacaca gggggagtcc tcgtgttgaa ggagatgaag atgaggatga tgttgatgat 781 atcgagaatg agttcaatta cgcccaggga gctaacaagg cgagacacca acgccatggc 841 gaagagtttt cttcttcctc tagacatgaa tctcaaccaa ttcctcttct cacccatggc 901 catacggttt ctggagagat tcgcacgcct gatacacaat ctgtgcgaac tacatcaggt 961 cctttgggtc cttctgacag gaatgctatt tcatctccat atattgatcc acggcaacct 1021 gtccctgtaa gaatcgtgga cccgtcaaaa gacttgaact cttatgggct tggtaatgtt 1081 gactggaaag aaagagttga aggctggaag ctgaagcagg agaaaaatat gttacagatg 1141 actggtaaat accatgaagg gaaaggagga gaaattgaag ggactggttc caatggcgaa 1201 gaactccaaa tggctgatga tacacgtctt cctatgagtc gtgtggtgcc tatcccatct 1261 tctcgcctaa ccccttatcg ggttgtgatt attctccggc ttatcatctt gtgtttcttc 1321 ttgcaatatc gtacaactca ccctgtgaaa aatgcatatc ctttgtggtt gacctcggtt 1381 atctgtgaga tctggtttgc attttcttgg cttcttgatc agtttcccaa atggtacccc 1441 attaacaggg agacttatct tgaccgtctc gctataagat atgatcgaga cggtgaacca 1501 tcacagctcg ttcctgttga tgtgtttgtt agtacagtgg acccattgaa agagcctccc 1561 cttgttacag caaacacagt tctctcgatt ctttctgtgg actacccggt agataaagta 1621 gcctgttatg tttcagatga tggttcagct atgcttacct ttgaatccct ttctgaaacc 1681 gctgagtttg caaagaaatg ggtaccattt tgcaagaaat tcaacattga acctagggcc 1741 cctgaattct attttgccca gaagatagat tacttgaagg acaagatcca accgtctttt 1801 gttaaagagc gacgagctat gaagagagag tatgaagagt ttaaagtgag gataaatgct 1861 cttgttgcca aagcacagaa aatccctgaa gaaggctgga caatgcagga tggtactccc 1921 tggcctggta acaacactag agatcatcct ggaatgatac aggtgttctt aggccatagt 1981 gggggtctgg ataccgatgg aaatgagctg cctagactca tctatgtttc tcgtgaaaag 2041 cggcctggat ttcaacacca caaaaaggct ggagctatga atgcattgat ccgtgtatct 2101 gctgttctta ccaatggagc atatcttttg aacgtggatt gtgatcatta ctttaataac 2161 agtaaggcta ttaaagaagc tatgtgtttc atgatggacc cggctattgg aaagaagtgc 2221 tgctatgtcc agttccctca acgttttgac ggtattgatt tgcacgatcg atatgccaac 2281 aggaatatag tctttttcga tattaacatg aaggggttgg atggtatcca gggtccagta 2341 tatgtgggta ctggttgttg ttttaatagg caggctctat atgggtatga tcctgttttg 2401 acggaagaag atttagaacc aaatattatt gtcaagagct gttgcgggtc aaggaagaaa 2461 ggtaaaagta gcaagaagta taactacgaa aagaggagag gcatcaacag aagtgactcc 2521 aatgctccac ttttcaatat ggaggacatc gatgagggtt ttgaaggtta tgatgatgag 2581 aggtctattc taatgtccca gaggagtgta gagaagcgtt ttggtcagtc gccggtattt 2641 attgcggcaa ccttcatgga acaaggcggc attccaccaa caaccaatcc cgctactctt 2701 ctgaaggagg ctattcatgt tataagctgt ggttacgaag acaagactga atggggcaaa 2761 gagattggtt ggatctatgg ttccgtgacg gaagatattc ttactgggtt caagatgcat 2821 gcccggggtt ggatatcgat ctactgcaat cctccacgcc ctgcgttcaa gggatctgca 2881 ccaatcaatc tttctgatcg tttgaaccaa gttcttcgat gggctttggg atctatcgag 2941 attcttctta gcagacattg tcctatctgg tatggttacc atggaaggtt gagacttttg 3001 gagaggatcg cttatatcaa caccatcgtc tatcctatta catccatccc tcttattgcg 3061 tattgtattc ttcccgcttt ttgtctcatc accgacagat tcatcatacc cgagataagc 3121 aactacgcga gtatttggtt cattctactc ttcatctcaa ttgctgtgac tggaatcctg 3181 gagctgagat ggagcggtgt gagcattgag gattggtgga ggaacgagca gttctgggtc 3241 attggtggca catccgccca tctttttgct gtcttccaag gtctacttaa ggttcttgct 3301 ggtatcgaca ccaacttcac cgttacatct aaagccacag acgaagatgg ggattttgca 3361 gaactctaca tcttcaaatg gacagctctt ctcattccac caaccaccgt cctacttgtg 3421 aacctcatag gcattgtggc tggtgtctct tatgctgtaa acagtggcta ccagtcgtgg 3481 ggtccgcttt tcgggaagct cttcttcgcc ttatgggtta ttgcccatct ctaccctttc 3541 ttgaaaggtc tgttgggaag acaaaaccga acaccaacca tcgtcattgt ctggtctgtt 3601 cttctcgcct ccatcttctc gttgctttgg gtcaggatca atccctttgt ggacgccaat 3661 cccaatgcca acaacttcaa tggcaaagga ggtgtctttt agaccctatt tatatacttg 3721 tgtgtgcata tatcaaaaac gcgcaatggg aattccaaat catctaaacc catcaaaccc 3781 cagtgaaccg ggcagttaag gtgattccat gtccaagatt agctttctcc gagtagccag 3841 agaaggtgaa attgttcgta acactattgt aatgattttc cagtggggaa gaagatgtgg 3901 acccaaatga tacatagtct acaaaaagaa tttgttattc tttcttatat ttattttatt 3961 taaagcttgt tagactcaca cttatgtaat gttggaactt gttgtcctaa aaagggattg 4021 gagttttctt tttatctaag aatctgaagt ttatatgcta agcttttcac tttactacaa 4081 aaagtttatg gatatgatgg tgtacgtcaa ttgttggtgc aagtgttgat gtcttcgggt 4141 gaactcgccc tcttgttttg tctcacccat cagtacaaat agaatgacat ttattttttt 4201 gaacttttaa cgaaatcttt g //