Dbfetch
LOCUS NM_079895 10287 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster apolipophorin (apolpp), transcript variant A, mRNA. ACCESSION NM_079895 VERSION NM_079895.3 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 10287) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 10287) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 10287) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 10287) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 10287) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 10287) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 10287) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 10287) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 10287) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 10287) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 10287) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 10287) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 10287) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 10287) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 10287) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 10287) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 10287) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 10287) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 10287) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 10287) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 10287) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 10287) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 10287) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004353). On Jan 16, 2013 this sequence version replaced NM_079895.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..10287 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="4" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..10287 /gene="apolpp" /locus_tag="Dmel_CG11064" /gene_synonym="ApoL1; ApoL2; apoLI; ApoLI; apoLII; ApoLII; apoLpp; apoLPP; Apolpp; ApoLpp; CG11064; chr4:1088013..1088173; Dmel\CG11064; DRBP; lipophorin; Lipophorin; Lpp; LPP; rfabg; Rfabg; RFABG; Rfabp; RfaBp; RfaBP; RFABP; RFBP; T3" /note="apolipophorin" /map="102F7-102F8" /db_xref="FLYBASE:FBgn0087002" /db_xref="GeneID:43827" CDS 142..10197 /gene="apolpp" /locus_tag="Dmel_CG11064" /gene_synonym="ApoL1; ApoL2; apoLI; ApoLI; apoLII; ApoLII; apoLpp; apoLPP; Apolpp; ApoLpp; CG11064; chr4:1088013..1088173; Dmel\CG11064; DRBP; lipophorin; Lipophorin; Lpp; LPP; rfabg; Rfabg; RFABG; Rfabp; RfaBp; RfaBP; RFABP; RFBP; T3" /note="CG11064 gene product from transcript CG11064-RA; CG11064-PA; apolpp-PA; retinoid-fatty acid binding protein; Retinoid- and fatty acid-binding glycoprotein; retinoid- and fatty acid-binding gene; Retinoid-fatty acid-binding glycoprotein; retinoid and fatty acid binding protein; Retinoid- and fatty acid-binding protein; Retinoid- and fatty-acid binding protein; apolipophorin II; lipophorin; RfaBp; retinoid and fatty acid binding glycoprotein; retinoid and fatty-acid binding protein; apolipophorin-2" /codon_start=1 /product="apolipophorin, isoform A" /protein_id="NP_524634.2" /db_xref="FLYBASE:FBpp0088252" /db_xref="GeneID:43827" /db_xref="FLYBASE:FBgn0087002" /translation="MARMKYNIALIGILASVLLTIAVNAENACNLGCPKSDNGLLKYI PGNYYDYSFDSILTIGASSDVPNDSDDTSLKVSGSAKIFAKGNCGYTLQLSSVKVTNT KESVEKKILNSIQKPVQFTLVSGILEPQICSDSSDLDYSLNIKRAVVSLLQSGIEAEH EVDVFGMCPTHTSTSKVGNANIITKARNLNSCSHREQINSGLVSGKVNEKAGITSSLL LQANYIKESRIVNHLIENVQLTETYKFIGNTKRNSDISAKVVTILKLKNPSGTKANSP GTGSTVRSLIFQRPETYTSKNINALKTILSDLVDSTGDYVKKETAKKFVEFIRLLRQS DSETLLELAAFPHPNKVLARKVYLDGLFRTSTAESARVILKQLSKFDEKEKLLAILSL NIVKSVDKETLNQAASQLLPNAPKELYIAVGNLVAKYCLKNYCQGPEIDAISKKFSDG LKHCKPNTKREEERIVYILKGLGNAKSLSGNTVAALSECASTGRSNRIRVAALHAFSK VKCEETLQSKSLELLKNRNEDSELRIEAYLSAISCPNAEVANQISEIVNSETVNQVGG FISSNLKAIRDSTDVSRDQQKYHLANIRVTKTFPVDYRRYSFNNEVSYKLESLGVGAS TDYQIIYSQHGFLPRSSRINVTTEFFGTNYNVFEASVRQENVEDVLEYYLGPKGLVNK DFDEIVKLIEVGNNGVAAGGRARRSIVDDVSKISKKYKMYGVKNVQDLNLDVSLKLFG SELAFLSLGDNIPSSLDDIINYFSTSFEKAKQELSSFEKQFSSHHLFLDTDLAYPTSI GVPLELVAQGFAATKVDLAVSLDINAILEQNWQKAKYRLKFVPSVDINANVQIGFNAQ VLSTGLRVVSSAHSATGSDITVAVISDGEGFNVDLELPREKLELINFNVDTELYVAEQ DKQKAIALKGNKKNKNSQPSEICFNQLELVGLNICIKSSTSLSEVQAGNGNVAERGLS VSEKFHLSRPFNFAVYLTTERKFTFKGIHTQEAFSQKWKLDYSTPGSKVSHDTTVVYE LGNKPKTFSRLSFDNSQCHFAVEGGINNDKNELVVYGQYEQDKEIKKSKIGFSKNGNE YKPLIEIQDNNGISNSINGYHADGKIVVKKNSNNIERYNFENFQVSNSNNAHVAVNGW SDVGTNSLTSELRISLDHQTFLIKENLKLENGLYEAGFFINDEHSPENIYGSSIHLTI ADQSYALKTNGKAAAWSIGSDGSFNFQKLADSNSARAGSLVENVEIQYKNKQVGGIKI MSNFDVNKMDVDVEISREQKIGSIIVKYESNQRHAQDYSLEASAKINKHSIDVISKCD FNGNVYVVDNSLVTSWGTLLSAKGEIGQRYSAQDININIQGNVQISGKDKVTQWILKV IGTPDKTNSDFRISRDTSELIKLTSESQHPQDKISFAKLNLIVKNQLTAKGEFRVAKN GKGDFTASIDTLKTEPKHKLEIESKFHIQSPKYDIDASLTLDGKRKVHLKSENTIEKL KFSTKNIGEANDKIIAFEANGSLKGELRGNGEIQGTFIFNAPDGRVIDGSINRKISTN AKSGLSQGNIDAQLSDTPFGSNKKRSISLIGKLDRLNTKTKEFSANSNLVYTAFNGEK SEISYQIKQQPNGDAKNIDFSLKAYGNPLPQPFEIAFALGDYSAQHAVVSITSKYGEI FSVSANGNYNNNQALEYGLQANIEIPKSTLKSLEINSHGKVLKSLIGNENAAYNVEFF LDSKTSLGQYARVNTVWNGTANDGSYDFEAQTNNMESPLKFNGKYHRKQTGNIKDGDL TGKQTYVLNAQYGAQYVKMDASLGYGAEKVDIAYVIDSSFDSVKDIKVNIRTFKPLDD STYVVTALFKQTDKSYGLDTTFYHSAHKKGVDIRLDLLKEKPIIISSIAELLGDRKGK VLFEILNLADLDIKINSEASYVSIDEFYIIVNWSSKKLKLDGYELEARAQSKNIKIQL KNENGIIFSGTATYALKKELNKTIIDGQGKVQYQGKALSGNFKLTRQHFDFGTDREVG FSYTFMGNLGSKNGLGTLKITNKEFNTKFSVCEEKRQCTNLIVQSIVSIDEQKLDAVE HTTLIIVDLRDFGYPYEFELKSQNTRQGLKYQYHLDSFIITGNNFKYQFTANVQPTSS TIKLALPKRQILFETTQKIPADGSLFGRYEQTASFFIDKLQKPDDVARFSAIVDVTGT ERVAFNANGKLKFEHPTIRPLSISGQLNGDVNQQIASAEVIFDIFRLPEQKVVGNSEL RNSRSQNGFNIAYITTVKSAGLQFQYQINSNAAVDIEAHEYNIGLELNNGEIDVKAIS FLNKEKFEISLSESNKHIIYIVGDFSKQNHYAKLNTKVQILDKNPIEITSEVQPNSAK IILKRQDFIDGTAEVKLGKEFKVDVIGSGKQLFNGRVALDATNFLQTNYFINEDHLNG FWHIVESEINKDSEYISENIKERLKKSRQVTDKIVKLAKEAGPDFSKLQGKLLDYKND IVQELEADQSIAPIIDGIRTLFKKIAGIVDDINKAISEILEKAQKSIVDIYDKLQALW KDSLLKAWEDFIITVQKLISTLKTEFIKICTQSFKDLLSALEKYGPALKNYGKAIGEI VKPINDAAQEVIKIVVNAAEGVTHEFKQYVASLPSFESIRNEFNDKVKVLKLFEKATE LTNSLFDQINILPQTPETSEFLQKLHDYLIAKLKQEHIDNEKYIEELGQLLIKAVRSI WVSIRSTYPGSSDHVIDFQSWIGSLTHSFDSLAVLPSILSFRSSILNCLLNENWDVVF NKKLLYSWIFFNDFELRGHVVDGKHIFTFDGLNFAYPGNCKYILAQDSVDNNFTIIGQ LTNGKLKSITLIDREGSYFEVADNLALKLNGNLVEYPQHLSGLHAWRRFYTIHLYSEY GVGIVCTSDLKVCHININGFYTSKTRGLLGNGNAEPYDDFLLIDGTLAENSAALGNDY GVGKCTAIEFDNNQFKSSKRQEMCSELFGIESTLAFNFITLDSRPYRKACDIALAKVA EKEKEATACTFALAYGSAVKQINKWVLLPPRCIKCAGPAGQHDFGDEFTVKLPNNKVD VVFVVDINVTPGVLSNLIAPAINDIRESLRSRGFSDVQVGVIVFEETKRYPALLTSDG GKINYKGNVADVKLAGIKSFCDNCVEQIITEKRILDIYNSLKEIVKGIAPQADEKAFQ LALDYPFRAGAAKSIIGVRSDSLEYKNWWKFVRAQLTGSITKFDGALIHLIAPVKGLS LEGVLSEKLIGFNSRLVATVDGKDSKKRTKLQFDNDMGIDFVLNNGGWVFATQNFEKL KASDQKKMLNQITSSLADTLFKTEIVSDCRCLPIHGLHGQHKCVIKSSTFVANKKAKS A" ORIGIN 1 cggcttaatt cgtagacaac gttcattgta ttcgaatcgg tttaattcgc ggatggtctg 61 tgtgtttctt aatctaagaa gtatatacaa agtgaaattg gaccagtgtt ggtaaaggct 121 atccctaagg ggcccagcgt aatggccagg atgaaataca atatcgcttt gattggaatc 181 ctagcttctg tgcttttaac aattgctgta aatgctgaaa acgcttgcaa tctaggatgt 241 ccaaaatctg acaatggact tttgaagtac atacccggca actactatga ctattccttc 301 gacagtattt taactattgg agcgagtagc gacgttccga acgactcaga tgatacaagt 361 cttaaagtgt ccggatctgc aaaaattttt gcgaaaggaa actgtgggta cacattacag 421 ttaagttccg ttaaggtaac taatacaaaa gagtctgtgg agaaaaagat attgaacagc 481 attcagaagc cagttcagtt tacactggta agtggaattt tagagccaca aatttgctca 541 gactccagcg acttggacta ctctttgaat attaagcgcg cagttgtatc attgcttcaa 601 tcgggaatag aagcggaaca tgaggttgac gttttcggca tgtgccctac acatacatca 661 acatcgaaag tgggtaacgc aaatataatt acgaaggcgc ggaacttaaa cagctgttcg 721 catcgcgagc agataaacag tggcttggtg tccggcaaag ttaacgaaaa agctggcatt 781 acgtctagcc tgctgttgca ggcaaactat ataaaggagt ccaggattgt aaaccactta 841 attgaaaatg ttcagctgac agaaacatat aagtttattg gaaatactaa aagaaactct 901 gatatcagtg caaaagtagt cacaatatta aaactgaaaa atccaagcgg taccaaggca 961 aactcaccag gaactggttc tactgtcaga agcctaatat ttcagagacc agaaacctat 1021 acctccaaaa atattaacgc cctcaaaacg attctatctg atctcgtaga ttcaactggc 1081 gactatgtga aaaaagaaac agctaaaaag tttgttgagt ttattaggtt gctacgccaa 1141 tctgatagtg agactttatt agaactggct gcgtttccac atccaaacaa agtcttagcc 1201 cgcaaggtat atttggatgg attatttcgg accagtacag ctgagtcagc tagagttata 1261 ttaaaacagc tttccaaatt tgatgagaag gagaaattac ttgcaatact gtccttaaac 1321 atagtgaaaa gtgttgacaa agagaccctc aatcaagcgg cttctcagct cttacctaac 1381 gcgcctaaag aactatatat agctgtgggt aacttagttg ctaaatattg tttaaaaaat 1441 tattgtcaag gaccggaaat tgatgccata tctaaaaagt tttctgatgg ccttaagcac 1501 tgtaagccaa atactaagcg ggaagaagag cgcattgtgt acattttaaa gggactagga 1561 aatgcaaaga gtttaagtgg caatacggta gctgcactaa gtgagtgcgc ttccacagga 1621 cgctccaacc gcatacgtgt cgcagccttg cacgcttttt caaaagttaa atgcgaagaa 1681 accttgcaat ctaaatcctt ggaacttctt aagaatcgta acgaagattc agagttgcgt 1741 attgaagctt atttgtccgc gatttcatgc cctaacgcag aggttgctaa tcaaatttcg 1801 gaaatagtta attccgaaac tgttaaccag gttggaggat ttatatcatc taatttaaaa 1861 gctatccgag actctacaga cgtcagcaga gaccagcaaa aataccattt ggctaacatt 1921 agggttacaa aaacatttcc cgttgactac agacgataca gttttaataa tgaggtttcc 1981 tataagcttg aatcccttgg tgttggcgcc agcactgatt accaaataat atattcgcaa 2041 catggattct tgccccgatc atctcgtatc aatgtaacaa cagaattttt tggcacgaac 2101 tacaatgtat ttgaggcaag cgtccgacaa gaaaatgttg aagacgtatt ggaatactat 2161 ttagggccga aaggattagt aaacaaagat tttgacgaaa ttgttaaact cattgaagtt 2221 ggcaataatg gtgttgctgc tggtggccga gcccgacgat caattgttga tgacgtttct 2281 aaaatttcga aaaagtataa aatgtatgga gtcaaaaatg tgcaagatct caatttagat 2341 gtgtcattaa aactgtttgg ttcggaattg gcatttttga gcctaggcga caacatacca 2401 agttccctag atgacattat aaactacttc tcaacttctt tcgaaaaagc aaaacaggaa 2461 ttatcttcgt ttgaaaagca attttccagt caccacttat tccttgatac agacctcgct 2521 tatccaacta gtattggagt acctttggag cttgtagccc aaggttttgc agctaccaaa 2581 gttgatcttg ccgttagtct tgatattaat gcaattctag aacaaaactg gcaaaaggct 2641 aagtatagac taaagtttgt tccgagtgtc gatattaatg ctaacgttca gataggcttt 2701 aatgcacaag tactatccac tggactccgc gtggtttcgt cagcccattc tgccaccggt 2761 agcgatatta ctgtagctgt tattagcgat ggagagggct ttaacgttga cctcgagcta 2821 ccacgcgaaa aacttgagct tattaatttt aatgttgaca cagaactata tgtagccgaa 2881 caagacaaac aaaaggcaat tgccctaaag ggtaacaaaa aaaataagaa ttctcaacct 2941 agtgagatat gctttaatca attggaactt gttggattaa atatttgcat taagagttca 3001 acaagcttaa gtgaggttca agctggtaac ggcaatgttg cagagagagg actttctgtt 3061 tcggagaaat ttcatttatc tagaccattt aatttcgccg tttacttaac gactgaacgc 3121 aaatttacat tcaaaggaat tcacacacag gaagctttct cccaaaagtg gaaattagat 3181 tattccactc ctggatccaa agtttctcac gatacaactg ttgtatatga actcggaaat 3241 aagcctaaaa catttagtag attatccttt gataactctc aatgccactt tgcagtggaa 3301 ggtggaataa acaacgacaa gaatgaattg gttgtatatg gtcaatacga acaagacaaa 3361 gaaataaaaa aaagtaaaat tggctttagc aaaaacggaa atgaatacaa gccattaatt 3421 gaaatccaag acaataatgg aatctcaaat agcataaatg gttaccacgc agacggaaaa 3481 atagttgtaa aaaaaaacag taataatatt gaaagatata attttgaaaa cttccaagtg 3541 tcaaattcta ataacgccca cgtagcagta aacggatggt cggatgttgg gacaaattca 3601 ttaacctctg agcttcgaat ttctttagat caccaaacct tcttaataaa agaaaattta 3661 aaattggaaa atggtctgta tgaggctggt ttcttcataa atgatgaaca ttctcccgaa 3721 aatatttatg gaagttcgat acatttaaca atagctgacc agtcttatgc tcttaaaact 3781 aacgggaaag cagctgcttg gtccattggc agtgatggta gttttaattt ccaaaaactt 3841 gccgattcca actctgctcg tgcaggctca cttgtggaaa atgtagaaat tcagtataaa 3901 aataagcagg tcggaggaat aaagattatg tcgaattttg atgttaataa aatggatgtc 3961 gatgtggaaa tttcgcgtga gcaaaaaatt gggtccataa tcgttaaata cgaaagtaat 4021 cagcgacacg cacaggatta ttccctggag gcaagtgcaa agattaacaa gcactccata 4081 gatgttatat ctaagtgtga ttttaacgga aacgtctatg ttgtcgataa ctctttagta 4141 actagttggg gaactttact atctgcaaaa ggagaaatag gacaacgtta ctcggcccaa 4201 gacattaata ttaatattca aggcaatgtt caaattagcg gaaaggacaa agttactcaa 4261 tggatactta aagtaatcgg cacacctgac aaaaccaaca gcgactttag gattagccga 4321 gacacctcag agcttattaa actaactagc gagtctcaac atccgcaaga taaaatatcc 4381 tttgccaaac ttaacttaat tgtcaaaaat caattaactg ccaaaggcga gtttcgtgta 4441 gccaaaaatg gaaagggtga ctttacagcc agtattgaca ctctgaagac tgaaccgaag 4501 cacaaactag aaatagaatc taaatttcac atacagtctc caaagtacga tattgatgct 4561 tccctaacac ttgatggaaa aaggaaagtg cacttgaagt cagaaaacac tatagaaaag 4621 ttaaaattct caactaaaaa cattggtgag gcaaacgaca aaataattgc tttcgaagct 4681 aatggaagtt taaaaggcga attgcgagga aatggggaaa tacaaggtac ctttatattt 4741 aacgctcccg atggtcgagt catcgacggc agtatcaatc gtaagatttc cacaaatgca 4801 aaaagtggct tatctcaagg caacattgac gcgcagctta gtgatacacc ttttggcagt 4861 aataagaaac gctcaatttc actaatcgga aagcttgatc ggctcaacac aaaaaccaaa 4921 gaattttctg caaacagtaa tttagtctac acggcattta atggagaaaa gtcggagata 4981 agttatcaaa ttaagcagca accaaacggg gatgctaaaa acatcgattt tagccttaag 5041 gcctatggaa atccactacc ccaacctttt gagatcgctt ttgccttagg agattacagt 5101 gcacagcatg ccgtagttag tatcacaagt aagtacggtg agattttttc tgtaagtgca 5161 aatggaaact acaacaataa tcaagcactt gaatatgggc ttcaggctaa tattgaaatt 5221 ccgaaatcca ccttgaagtc cttagaaata aacagtcatg gaaaggtcct aaaatcttta 5281 atcggaaatg aaaacgctgc atacaatgta gaattcttcc tggattctaa aaccagtcta 5341 gggcaatatg ctcgtgtcaa tacagtatgg aacggcacgg caaatgatgg cagctatgat 5401 tttgaagctc aaactaacaa tatggagtct ccattaaagt tcaatggtaa atatcatcgg 5461 aaacaaacag gtaatataaa agatggtgac cttaccggta aacaaacgta cgtacttaac 5521 gcacagtacg gagcacaata cgtaaaaatg gatgcttcat taggttatgg agccgagaaa 5581 gtagatatag catatgttat agattccagc tttgattctg taaaagatat caaagttaat 5641 attcgcactt ttaaaccttt ggatgattcg acatatgtag tcactgcact attcaaacag 5701 actgacaagt catacggatt agacacaaca ttttatcatt cggcccacaa aaaaggtgtt 5761 gatattcgtt tagatctgtt gaaagaaaag ccaattatca tatcgagcat tgctgaactc 5821 ttaggagacc gaaaaggaaa ggtactcttt gaaattctaa acttggccga tttggacatt 5881 aaaataaata gtgaagcttc atacgtcagc attgatgagt tttatataat tgtcaactgg 5941 agctcgaaga aattaaagct cgatggctac gaacttgaag cacgagctca aagtaagaac 6001 attaaaattc aacttaagaa tgaaaatggc ataattttct caggtacagc cacttatgct 6061 cttaaaaaag aactaaacaa aactattatc gatggacaag gcaaagtgca gtatcaagga 6121 aaggcgctca gtggcaattt taagcttacc cggcaacact ttgattttgg tactgatagg 6181 gaagttggtt tctcttacac ttttatgggt aatttaggat cgaaaaacgg attaggcact 6241 ttaaaaatca caaacaagga attcaacacc aaattttccg tttgtgaaga aaagagacag 6301 tgtacaaatt taatagtaca atcaattgtg agcattgatg aacaaaaact ggacgctgtg 6361 gaacatacca cacttattat tgttgacctg agagattttg gatatccata cgagtttgaa 6421 ttaaagtctc aaaatacacg tcaaggtctt aagtatcagt accatttaga tagctttatt 6481 ataacaggaa ataatttcaa gtaccaattt acagccaacg ttcagcccac gtcgtccaca 6541 attaaattag cactcccgaa acgtcaaatt ttgttcgaaa ctactcagaa aataccagca 6601 gacggaagcc tttttggccg ctacgagcaa acagcttcat tctttattga caagttgcaa 6661 aagcctgacg acgttgcccg cttttctgct attgtagatg taacgggcac cgaacgcgtt 6721 gcattcaacg ccaacgggaa acttaagttt gaacatccaa ctattcgtcc attaagtatt 6781 tctggacaat tgaatggaga cgtgaatcaa cagatcgcaa gcgccgaagt aatatttgat 6841 attttccgac tgccggaaca aaaagtggtt ggaaacagtg aattgcgcaa ctcccgttct 6901 caaaatggtt tcaatattgc atatattaca actgttaagt ctgctggcct tcagtttcag 6961 taccaaataa atagtaacgc tgcagtggat attgaagccc atgagtataa cattggcttg 7021 gaattaaata acggtgaaat cgatgttaag gcgatttcgt ttttaaataa ggaaaaattt 7081 gaaatctctt taagtgaatc aaataaacat atcatttata tagtcggaga cttttctaag 7141 caaaaccatt atgcaaagct taatacaaag gttcaaattc ttgataaaaa tccaattgaa 7201 attacatcgg aggttcaacc taattctgca aagattatac tgaagcgtca agatttcatc 7261 gatggcactg cagaagttaa gctgggcaag gaatttaaag tagatgtcat tggaagtggg 7321 aaacaattat ttaatggccg agtggcatta gatgcaacaa actttttaca aacaaactac 7381 tttataaatg aagatcatct aaatggtttc tggcatattg ttgaatcgga aataaataaa 7441 gatagtgaat atatttctga aaatatcaag gaacgcttaa aaaaatctcg tcaagttacg 7501 gataaaattg ttaaattggc taaagaagct ggaccagatt tttccaaact gcagggtaaa 7561 ttacttgatt ataaaaatga tattgttcaa gagcttgagg ctgatcaatc aattgcaccg 7621 attattgatg gcatacgcac cctatttaaa aaaatagccg gtattgttga tgacataaac 7681 aaggcaatat cagaaatatt ggaaaaggct cagaagtcca ttgttgatat ttacgataaa 7741 ttgcaagccc tttggaagga ttcccttctt aaagcctggg aagatttcat tataactgta 7801 cagaaactaa taagtacact caaaactgag tttatcaaga tttgtacaca gtcatttaaa 7861 gatctccttt ctgcgcttga gaaatatgga ccagctctga aaaactatgg aaaagctatt 7921 ggagaaattg taaaacctat aaacgacgct gctcaggaag tcattaaaat tgtggttaat 7981 gccgctgaag gtgtaaccca tgaattcaag caatatgtcg caagccttcc gtcatttgaa 8041 agtattcgta atgagtttaa tgacaaagtt aaagttctga aactatttga aaaggcaaca 8101 gagttaacaa atagtctatt tgatcagatt aacattttac cacagacccc agagacttcc 8161 gagtttctac aaaaactcca cgattactta atcgctaaat taaagcaaga acatattgat 8221 aatgaaaaat acatcgaaga acttggacag cttttaataa aggctgttcg ttccatttgg 8281 gtctcgatta gaagcactta tccaggctca tcggatcatg taattgattt tcaatcttgg 8341 attggttctc taacgcattc ttttgactca ttggctgttc ttccgagcat actttcattc 8401 cgttcaagta tcttaaactg tttattaaat gagaattggg atgtagtatt taacaaaaag 8461 ctattatact catggatatt ctttaacgac ttcgaactac gaggccatgt cgtcgatggg 8521 aagcatatat tcactttcga cggcctgaat ttcgcgtatc cgggcaactg caaatatatt 8581 ctcgctcagg acagtgttga caataacttc acaataattg gtcagcttac aaatggaaaa 8641 cttaagagca ttacgcttat agatcgggag ggtagctatt tcgaagtagc agacaacctt 8701 gccctgaagc taaatggaaa cctagttgaa tacccacaac acttgtctgg tcttcacgcg 8761 tggcgccgat tttacactat tcacttatat tctgagtacg gagtaggcat agtatgtaca 8821 tcagacctga aggtttgcca catcaacata aacggatttt acacaagcaa aaccagagga 8881 cttctcggca acggcaacgc agaaccatat gatgacttct tgctaatcga tggtacctta 8941 gccgaaaatt cggccgccct aggcaacgac tatggagtag gaaaatgcac agcaattgaa 9001 tttgacaata accagtttaa aagctccaaa agacaggaaa tgtgtagcga actgtttggt 9061 attgaatcga ctctggcttt caatttcatt accttggatt cgagacctta ccgcaaggca 9121 tgtgatattg cacttgcaaa agtggctgaa aaggaaaagg aggccactgc gtgcacgttt 9181 gctttagctt atggttcggc agttaagcag attaataagt gggtgctatt accaccgcgt 9241 tgcattaagt gcgcaggacc tgctggacaa cacgactttg gagatgagtt tactgttaag 9301 ttaccaaaca acaaggttga cgttgtattt gtcgttgata tcaatgtaac acccggagtg 9361 ctgtctaatt taatagcgcc ggccatcaat gatattcgtg aatcattaag aagccgggga 9421 ttttcagatg tacaagtcgg agtgattgtt ttcgaggaaa ccaaacgata tcccgctcta 9481 ctcacaagtg atggtggcaa aattaactac aagggaaacg ttgctgatgt taagctggct 9541 ggaataaaga gcttctgtga caattgtgtg gagcaaatta taactgaaaa acgaatttta 9601 gatatttaca attctttaaa agaaatagta aagggcattg caccccaagc agatgaaaag 9661 gcgttccaat tggctttaga ttatcccttc cgcgctgggg cggcaaaaag cattatcggt 9721 gtgcgaagtg attctttaga atataagaat tggtggaaat ttgttcgagc tcagttaact 9781 ggatccatca ctaagtttga tggtgcactt attcatctta ttgcaccagt aaaggggctc 9841 tcattagaag gagtgttaag cgaaaaacta attggcttca attctcgatt ggtggctact 9901 gtagatggga aagacagcaa aaaacggact aagctgcaat tcgataacga catgggcatt 9961 gactttgtcc ttaataacgg tggctgggtg tttgccacac aaaactttga aaaattaaaa 10021 gcttcggacc aaaagaaaat gttgaatcag attacatcat cgctggcaga tactctcttt 10081 aagacggaaa tcgtcagtga ctgtcgctgt cttccgattc atggattgca cggccaacat 10141 aagtgcgtca ttaagtcatc aacatttgtt gcgaacaaaa aggcaaaatc tgcctaaact 10201 gggcttacat gttttatcga atcccttcgt gaggaaaaat ctttttttaa actaagtaaa 10261 acgaaaaatt aataaaaact taatatc //