Dbfetch
LOCUS NM_079223 8230 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster nudel (ndl), mRNA. ACCESSION NM_079223 VERSION NM_079223.2 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 8230) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 8230) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 8230) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 8230) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 8230) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 8230) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 8230) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 8230) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 8230) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 8230) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 8230) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 8230) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 8230) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 8230) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 8230) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (10-NOV-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 8230) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 8230) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 8230) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 8230) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 8230) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 8230) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 22 (bases 1 to 8230) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 8230) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 24 (bases 1 to 8230) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 25 (bases 1 to 8230) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Nov 6, 2002 this sequence version replaced NM_079223.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..8230 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="3L" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..8230 /gene="ndl" /locus_tag="Dmel_CG10129" /gene_synonym="CG10129; Dmel\CG10129; mat(3)2; mel(3)5; Ndl; nud; SP89" /note="nudel" /map="65B5-65B5" /db_xref="FLYBASE:FBgn0002926" /db_xref="GeneID:38738" CDS 269..8119 /gene="ndl" /locus_tag="Dmel_CG10129" /gene_synonym="CG10129; Dmel\CG10129; mat(3)2; mel(3)5; Ndl; nud; SP89" /EC_number="3.4.21.-" /note="CG10129 gene product from transcript CG10129-RA; CG10129-PA; ndl-PA" /codon_start=1 /product="nudel" /protein_id="NP_523947.2" /db_xref="FLYBASE:FBpp0076693" /db_xref="GeneID:38738" /db_xref="FLYBASE:FBgn0002926" /translation="MNYNMDEMEATRLLRHPRRWWSIGFGKRIVAISILVIIVLLFSL VYHGLVVEKIDQVQQIAALNARHQVLFNQPFEEDQSALIVSPQTLHFKLLDEDMNKDM EDSKNRRRKHMRQMLVKFRLNKKHRMRRDLHGLDLLDPVRMEANMQHLYTKLRSKRAR EALSQLEHEFVRCKKHTPQDCMSAFLRMYKMAKEVTEKMEKMKAIMREQQPKLESSSM ESHEQKGTFSPADLIQVTTAEATTVAVHATEKPARTKIKPSRISWIIDGHDHDESPVY TDGAPKKETTKAPWNTTQLVEITTTKIDATATERTTVESTTEKISWILDHFDKPQEIL RTTEGPGQRIIRNVTTTSASSEPIVDTENTNSDHVPTTENGLVFNITTDGPVETTKST AQRKLSFDWILDGEENVEPEVKSTNTTTTTAATTTTGATSETIIVTTELPKITFDWII DGREVVEPQETTTEVTGTTERLRKMPFDWIIDGEEVVEPQENVTTTTIATTVAVSTTE INERIHNSTAYPTKPKPVKFDWIIDGGESSGEVSTSSTSQPKLTTREAISNPESPRSS HPLDNPTSIENMLESFEQHEEQKPILRVLNANESSSETVTDGYERQLWLKKFEDQARP NQNELIDTFGTALDAKALDKMGPKINPLNGHTWNAADAQILSLCERVALRMRNKVATM SDGETKEKGETFTASPSVQFTSRAPGGFPVSGETMKASAQFMFNPNFGMPSIPVCFYM TPANFRMPMWSNTPTFMGMQGAHFGGSSNPGAGIFFVPQQFGPSGNFFGGSGGSGAGG QGANIFSKNASPQKPTNGQQQVYCSYMQNQSGQGAGQSQTSSQQQQGGQSAFSNANFK MRHANQTNTANQQGQIIYASYAGLPQQPIQERSRCPEPDQFSCFGQQECIPAARWCDN VVDCSDGSDESACTCADRVDEERLCDGYEDCPMGEDELGCFGCESLAYSCYENPQDFA KRNRSTISMCYSRLERCDGFMNCLNGRDEEQCSMLVTDVADHMSHGASASEGYLYHNY RGDWHPVCNNGEKWAALACQMDENSRMDHSASLNVSFQTLTLPGPFIEPSLHAGVHFA QACHGRNSHDSLVDHVAYVKCPPMQCGLPSKSSMLEHSKRVRRAVSDSKEIVGDGRIV GGSYTSALQWPFVVAIYRNGKFHCGGTIYSDRWIISAAHCVINYGKYFYEVRAGLLRR SSYSPATQIQPVSHVVVHQAYERRSMRNDLSLLRLLNPLQFNRWVKPICLPDKGRTTV GDDWIWGPVEHTLCTVVGWGAIREKGPSSDPMRQVIVPIRKKCTDPEDQASEDICAGD PDGGRDACQGDSGGPLFCRSVSNPDEFYLAGVVSHGNGCARPQEFGVYTRVTLYLDWL EMATTPRLLPKLQPLQLCPGFICVWGGKRCIAKRQRCDRNVDCLGGEDEVGCTYNFLP DMVGGVRQNISTTTESDYHPVKESEEKSKMREVIPIDDEDLKAEQDEEDLLKSTTSLG QTETTQGPMDLSFAEQITSTTSDDLSITDETTSTDFTVSDSATSPSTLLPTTTNPSTW LPSTNIETSTFSFTTTESEASTKQETLPTTVAQTTTIPTSTEDLKKLTDLVTEFIEST TFETTMEVETTTLSLTSTDAPKLVTTEGVKETTTTEDTTTISSIVTLTTTPLATISTT ILTTEKHVAVTTLAPTTTTESAKTTTTHSSSTHSEKDQIQIPNKFVCKKMSQIVDIMM RCDRKVDCEDGTDELDCTCKDYLKGSLKGLICDGKADCEDLTDEQNCVECQSNEFRCP LSKTCLPLSSRCDNKVDCKFKEDEKDCFALTNGHDVHFDVHQQPKFSSTGIFSRNGHG VWRVVCAHETGYHEHQAKTADAVCALLGFNGAHYFNSSEFVTQHEMQPITPELKGGRN RMSAQIHSMVGDNVQFTENEVIIPELGHPSASRPEKDRLLPRKCVGIYVECNPYSNKT TPLKTFSAGQVVKEKPIEQVPVLSPTIETHNTPNVHFKPQIPAMVVNKKDEILDRLDK LIKSKKNKTILVNEQLHEAIEELHWPWLADVYMNGDLWCIGVLIDKHWVMVHESCLSG IDLETHYVSVLLGGGKTKRSAHRSNHEQIRRVDCFEGVPKSNVLLLHLERPVRFTHHV LPTFLPDSSHQNQSHARQCISVLHDDATGRIKTVAITRIHNATNCDSCYKLQEKQPPA NLMRLLNVSAEDMASISEEVELINGVAPTELPAITKFTTCNQFGLKNVSDAHHNPSDQ GVLVCRDSHTGWFPTALFNYNNSDCQSFKQPFGIRTLELVYKSLQDIIDKPSCKMLLP APDCSTHRCPLGTCLPQAAMCNGRSDCHDGSDEEETKCRQQKQQCAPGEMKCRTSFKC VPKSKFCDHVPDCEDMTDEPTICSCFTYLQATDPSKICDGKRNCWDKSDESSVLCNCT ADHFQCSSSPEDCIPRDFVCDKEKDCPNGEDERYCFGIEHPLHLQKKDFWTNSQHTQP EIAPQYGQVIEQTYGIWHTKCFPKSKPPQVDEVREICKKLGYNPYRQPSYRLIDDEEN KPVHTYELADRQGRSFSNESLMGKYRDSTKALIISKFSPLQLNERLTLFLKSSRPIAE LVRWNATDSSMCYRLEIRCA" ORIGIN 1 ccggccggat cgcgcggaag tcgtcatcgt agtgattatt accgttctgg attatcgtgc 61 atatcaaatt gctttgcgat tgctttttgt ggatttttgt ttgagtgaat cgctgtaacc 121 tgaggctcct tgtttcccgg ccaatttaac aaagtgctta acatataatt gaaagaaata 181 atcagcgatt ttgtggcgta aaagcttatg tgttaaaaat gtccagagct taagtgaaaa 241 atccagaaga taaatcaatt tatgaataat gaattacaac atggatgaga tggaggccac 301 caggctgctt cggcatccgc gacgttggtg gagcattgga ttcggcaaac ggatcgtggc 361 catctcgatt ctggtcatca tcgtgttgct attttctctg gtttaccacg ggctagtggt 421 ggagaaaatt gatcaagtgc agcagattgc agcgctgaat gccaggcacc aggtgctttt 481 caaccagccc tttgaggagg atcagtctgc cctgattgtg agtcctcaaa ctttgcactt 541 caaattgctc gacgaggata tgaacaagga tatggaggat agcaaaaaca ggagaaggaa 601 gcatatgcgg caaatgctgg ttaagttccg gttgaacaag aaacaccgca tgcggcgtga 661 tttgcatggg ttggatctgt tggatcccgt ccggatggag gccaatatgc agcacctgta 721 caccaagctg cgaagtaaaa gggcaagaga agccctaagc cagttggagc atgagtttgt 781 gcgttgcaaa aagcatactc cgcaggattg catgtccgcc tttctgcgca tgtacaaaat 841 ggcaaaggag gtgaccgaga aaatggagaa gatgaaggcc attatgcggg agcagcagcc 901 gaaattggaa tcaagcagca tggagtccca tgaacagaag ggtacttttt caccggccga 961 cctgattcag gtgacaactg cagaggccac aacggttgcg gtacatgcca ctgaaaagcc 1021 agcgaggact aagattaagc cttcaaggat cagctggatc atcgatgggc acgatcatga 1081 cgagagtcca gtttatacag atggtgcccc caagaaggaa acaaccaagg caccttggaa 1141 caccacacaa ttggtcgaaa ttacaaccac aaaaatagat gcaaccgcta ccgaaagaac 1201 gactgtggag agcactacag agaaaataag ctggattctg gatcactttg acaagcccca 1261 agagatttta cgtacaaccg agggaccagg gcagcgaatc attagaaatg taaccaccac 1321 atcggcatcc tccgagccaa tagttgacac ggaaaacact aacagtgatc acgtgcccac 1381 cacggaaaac ggattggtat tcaatataac taccgatgga ccagtggaaa ctacgaaatc 1441 caccgctcag cgaaaattgt cattcgattg gatactggac ggagaggaaa atgtagagcc 1501 ggaagtcaag tccaccaaca ctacgacaac aactgcggcg accacgacga caggagccac 1561 ttcggaaacc atcattgtca ccacagagct gccgaaaata acttttgatt ggattattga 1621 cggaagggaa gtggtagagc cgcaggaaac tactactgaa gtcactggga ccacggaaag 1681 actgcgtaag atgccattcg attggattat tgacggggaa gaagttgtgg agccgcagga 1741 gaatgtcacc accacaacca ttgcgacaac tgtggcagtc agcacaaccg aaatcaacga 1801 gagaattcat aattccactg cctatcccac taagccgaag ccggtcaagt ttgactggat 1861 catcgatgga ggagagtcca gtggtgaggt aagcactagc tccacaagcc aaccaaagtt 1921 gactactagg gaggcgatca gcaatccaga atcaccacga tcctcacatc cgctggacaa 1981 ccctaccagc atcgaaaaca tgctggaaag ctttgagcaa cacgaggagc agaaacccat 2041 tctcagggtc ttaaacgcaa atgaatcctc ctcagaaacc gtgacggatg gctacgaacg 2101 tcagttgtgg ctgaagaagt ttgaggatca ggcaaggcca aatcaaaacg aactcataga 2161 tacttttgga accgctctag atgctaaagc cctagacaaa atgggaccca aaatcaatcc 2221 acttaacgga cacacttgga atgctgccga cgcccaaatt cttagtcttt gcgaacgagt 2281 ggctctgcgg atgcgcaaca aagttgccac catgtcagac ggtgagacga aggagaaggg 2341 tgaaaccttc acggcttcac ccagtgtaca gtttaccagt cgagctcctg gcggatttcc 2401 agtgtccggt gaaacaatga aggcctcagc acagtttatg tttaacccca acttcggaat 2461 gcccagcatt cccgtttgct tctacatgac gcctgccaat ttccgtatgc ccatgtggtc 2521 gaatacgccc acatttatgg gcatgcaggg tgcgcacttt ggaggatcat cgaaccctgg 2581 cgcaggcata ttttttgtgc ctcagcagtt tggaccgagc ggaaacttct tcggcggaag 2641 tggcggatcc ggagccggcg gccagggtgc caatatcttc tcgaagaacg cctcaccaca 2701 gaaaccgaca aacggccagc agcaggtcta ctgcagctac atgcagaatc aatcgggtca 2761 gggagcagga caatcgcaga catccagtca gcagcagcag ggtggacagt cggcattctc 2821 caatgccaac tttaagatgc gtcatgccaa tcagacaaac accgccaatc aacagggaca 2881 aatcatctat gccagctatg caggattgcc acaacaaccc atccaggagc gatccagatg 2941 cccagagccc gatcagtttt cctgcttcgg tcaacaggag tgcattcctg ccgcgagatg 3001 gtgtgataat gtggtggatt gttcggatgg cagcgatgag tccgcctgca cctgtgcaga 3061 tcgcgtggat gaagagcgtc tgtgcgatgg ttacgaagat tgccctatgg gcgaggacga 3121 gctgggatgc tttggctgcg aatcgttggc ttactcctgc tatgaaaatc cacaggactt 3181 tgccaaacgc aatcggtcta cgatttctat gtgctacagt cgactggagc gttgcgacgg 3241 attcatgaac tgtttgaatg gacgcgatga ggagcagtgc agcatgttgg tcaccgatgt 3301 ggcggatcat atgtcccacg gtgcatctgc ttctgaaggc tacctctacc acaattatcg 3361 cggggattgg catcctgtgt gcaacaatgg tgaaaagtgg gcggctttag cctgtcagat 3421 ggatgaaaac agtcggatgg atcactcagc ttcgttgaat gtcagtttcc aaaccctaac 3481 tttacctggt ccttttattg agccatccct gcatgctgga gtccactttg ctcaggcgtg 3541 ccatggacgc aatagccacg attccctagt agatcatgtg gcctatgtca agtgcccccc 3601 gatgcagtgc ggcctgccct ctaaatcatc tatgctggaa cactcgaaga gagtaagaag 3661 agcagtatcg gattcaaagg aaatcgttgg cgatggccga attgttggtg gaagttatac 3721 aagtgcactc caatggccat ttgtggtggc tatctataga aatggaaagt tccattgcgg 3781 tggaaccatt tattctgatc gttggatcat cagcgctgcc cactgtgtca taaactatgg 3841 aaagtacttc tatgaagttc gtgctggtct tctgcgtcgc tctagctact cacccgccac 3901 tcagatccag cccgtctccc atgtggttgt ccaccaagcc tacgaaagaa gaagtatgcg 3961 caacgatctc tctctgcttc gcctgctgaa tccgctgcag ttcaatcgat gggtgaaacc 4021 tatttgctta cccgacaagg gaagaactac agtaggcgac gattggatct ggggccccgt 4081 ggaacacacc ctatgcacgg tggttggttg gggagccatc agagagaagg gtccaagcag 4141 tgatcccatg cgccaggtta tcgtaccaat tcgtaagaaa tgcactgatc cagaagatca 4201 ggcttcagaa gacatttgtg ctggcgatcc agatggaggt cgcgatgcct gccagggtga 4261 ttcgggtggg cctctcttct gtcgcagcgt ctctaaccca gatgagttct atctggccgg 4321 agtagtaagc catggcaatg gctgtgctcg tcctcaggag tttggagtct acacgagggt 4381 cactctctac ctggactggt tggaaatggc tactactcca cgactgttgc ccaaacttca 4441 gccgcttcaa ctgtgtccag gatttatctg cgtgtggggc ggtaagcggt gtattgctaa 4501 acgacagcgc tgcgatcgca acgttgattg tttgggtggc gaggatgagg tgggatgcac 4561 ctacaacttt ttaccagata tggtgggtgg cgttcgacag aatattagca ccacaactga 4621 gagtgactat catccagtga aggagagcga ggaaaagagt aaaatgcggg aggttattcc 4681 cattgacgat gaagatttaa aggctgaaca agacgaggaa gatttattga aaagcacaac 4741 atctttaggg caaactgaaa caacacaggg cccaatggat ttatctttcg ctgaacaaat 4801 tacttcaact acctcagatg atctatcaat aacagatgaa accacgagca cagattttac 4861 agtgagtgat tcagccacta gcccttccac tcttttgcca acaacgacaa atccttcaac 4921 ttggttgcca tccacaaata ttgaaacatc aacattttca tttactacaa ctgaatctga 4981 agcttcaacc aaacaagaaa cattaccaac tactgttgcc caaactacga caatcccaac 5041 ttcaactgaa gacctaaaga agctcacaga tttggtcact gaatttatag agagtacgac 5101 ttttgagacc acgatggaag tggagacgac tactttatct ctaacctcaa cagacgctcc 5161 aaaattagta acaacagagg gagtgaagga aacaacaacc acagaagaca caaccacaat 5221 tagcagcatt gttactctta ccaccacgcc cttggccaca atctctacta ccattctaac 5281 cactgaaaag catgtagctg taaccacatt agcaccaact actactacag agtccgccaa 5341 gacgacaaca acgcatagta gcagcactca ttctgaaaag gatcaaatac aaattcctaa 5401 taaatttgtg tgcaaaaaga tgtctcaaat tgtggatatt atgatgcgtt gtgataggaa 5461 agtggattgc gaggatggaa ctgatgaact ggactgcaca tgcaaagatt atttgaaggg 5521 atctctgaag ggactcattt gcgatggcaa ggcagattgc gaggacctca cggatgaaca 5581 gaactgcgtg gaatgtcaat caaacgaatt ccgttgcccg ctgtctaaaa cttgtttgcc 5641 attaagcagt cgttgcgata ataaagtgga ttgcaagttc aaggaagatg aaaaggattg 5701 ctttgctttg accaatggcc acgatgtgca ctttgatgtg catcagcagc caaagttcag 5761 cagtaccgga atcttctcca gaaacggcca tggcgtgtgg cgggtagtct gtgctcatga 5821 gactggctat cacgagcacc aggccaaaac agcagatgcg gtctgtgctc tccttggttt 5881 caatggagct cactacttca atagctccga gtttgtgacc cagcatgaaa tgcaacccat 5941 cacaccggag ttaaaaggag gcagaaaccg catgtcagca caaattcatt ctatggtcgg 6001 tgacaatgtc caatttactg agaacgaggt cataatacca gaactgggac acccatccgc 6061 ttcaagacca gagaaggatc gtctgttgcc ccgcaagtgt gtcggcatct acgtggagtg 6121 caatccgtac tccaacaaaa ccacacccct aaaaacattc agtgctgggc aagttgtcaa 6181 ggaaaagcca attgaacagg ttcctgtcct atcgcccacc atcgagacgc acaacactcc 6241 caatgtgcat tttaagccgc aaattccggc gatggttgta aataaaaaag atgaaatttt 6301 ggatcgtctg gacaaactca tcaagagtaa gaaaaacaaa accatactgg ttaatgagca 6361 gctccatgaa gccattgagg agctgcactg gccctggctg gcagatgtgt atatgaatgg 6421 cgatctctgg tgcatcggag tgctgattga caagcattgg gtaatggtcc acgagagctg 6481 cctgtctggc attgacttgg agactcacta cgtcagcgtt ttgctgggcg ggggcaaaac 6541 aaagcgatcg gcccacagga gcaatcacga acagattcgg cgtgtggact gctttgaggg 6601 agtgccaaag tccaatgtgt tacttttgca tctggagcgc cctgtgcggt tcacccacca 6661 tgtgttgcct accttcctgc ctgacagttc ccatcaaaat caaagccatg cgaggcagtg 6721 catcagtgtg cttcatgacg atgccacagg acgcatcaaa accgtagcca ttacccgtat 6781 acacaatgct accaattgcg attcctgcta caagctgcag gaaaagcaac caccggctaa 6841 tctgatgcgc ctgttaaatg tgagtgccga ggatatggct tccatttcgg aggaggtgga 6901 actcattaat ggtgttgctc ccacggagct accggccatt accaaattca ccacctgcaa 6961 ccaatttggg ctgaaaaatg ttagcgatgc acatcacaat cccagcgatc agggtgtatt 7021 ggtctgtcgg gactcgcaca caggctggtt cccaacggcc ttgtttaact acaacaattc 7081 cgactgccaa agttttaaac agccatttgg tattagaacg ttagaactgg tatacaaatc 7141 gctgcaggat atcatagaca aaccgagctg caaaatgctc ctaccagccc cggattgctc 7201 cacccatcgt tgcccgctgg gtacctgttt gccgcaggct gcgatgtgca acggccgctc 7261 cgattgtcat gatggcagcg atgaggagga aaccaaatgc cgacagcaaa agcagcaatg 7321 tgcccctggc gagatgaagt gtcggaccag cttcaaatgc gtgccgaaaa gcaagttttg 7381 tgaccacgta cctgactgcg aggacatgac ggatgagccg accatctgca gttgtttcac 7441 atatctgcaa gccactgatc cgtcaaagat atgcgatggc aagcgaaact gctgggacaa 7501 gagcgacgag agttcagtac tgtgtaactg cacagcggat cacttccagt gcagttcctc 7561 ccccgaagat tgcattcctc gtgattttgt gtgcgacaaa gagaaggatt gtcccaatgg 7621 agaagatgag cggtattgct ttggcataga gcacccattg catctgcaga agaaggattt 7681 ctggaccaat agtcagcaca cgcaaccgga aatagctcca caatacggtc aagttatcga 7741 acagacctat ggcatctggc atacaaaatg cttcccgaaa agtaaacccc cgcaagtgga 7801 tgaagtgcgt gaaatatgca aaaagttggg ctacaatcca tatagacagc ctagttatcg 7861 attgattgac gacgaggaga acaaacccgt gcacacctac gagttggcgg ataggcaagg 7921 tcgaagtttc agcaatgagt cgctgatggg caagtatcgc gactcaacaa aggcgttaat 7981 catcagcaaa ttctcgcctc ttcaactgaa tgagcgcctt acattgttcc tcaagtccag 8041 cagaccaatt gccgagctgg ttagatggaa tgccaccgat tccagcatgt gctacagact 8101 ggagatcaga tgtgcctaaa aacctaaaag atgacaacat ttacttggta agaggttctt 8161 tcgtactctc gtgatagtcc ttttgtgcgt tttagtagca aataaatgcg agagctgtac 8221 acattttatt //