Dbfetch
LOCUS NM_078977 10470 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster toutatis (tou), transcript variant A, mRNA. ACCESSION NM_078977 VERSION NM_078977.5 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 10470) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 10470) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 10470) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 10470) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 10470) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 10470) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 10470) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 10470) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 10470) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 10470) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 10470) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 10470) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 10470) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 10470) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 10470) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 10470) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 10470) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 10470) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 10470) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 10470) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 10470) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 10470) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 10470) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 24 (bases 1 to 10470) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jan 16, 2013 this sequence version replaced NM_078977.4. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..10470 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="2R" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..10470 /gene="tou" /locus_tag="Dmel_CG10897" /gene_synonym="anon-48Ad; CG10897; Dm Tou; Dmel\CG10897; EP(2)0622; EP0622; EP622; gene VI; TIP5; Tou; TOU; VI" /note="toutatis" /map="48A1-48A3" /db_xref="FLYBASE:FBgn0033636" /db_xref="GeneID:36241" CDS 524..9523 /gene="tou" /locus_tag="Dmel_CG10897" /gene_synonym="anon-48Ad; CG10897; Dm Tou; Dmel\CG10897; EP(2)0622; EP0622; EP622; gene VI; TIP5; Tou; TOU; VI" /note="CG10897 gene product from transcript CG10897-RA; CG10897-PA; tou-PA; transcript group VI; toutatis" /codon_start=1 /product="toutatis, isoform A" /protein_id="NP_523701.3" /db_xref="FLYBASE:FBpp0087193" /db_xref="GeneID:36241" /db_xref="FLYBASE:FBgn0033636" /translation="MNKNAGDGSDGKNSNKNSNAGGGGGAGGPHDPTGLLDAASLFAY WGRDPTGAAAAAASNPLFNSQFNAAAAAGLGLLPQAGGASANDRYSMAAAAAAAAGAH HHQNTMAVAASQAASLAGLHPASWWSMAQLAAQDYFSRLQASGLSPFPHPDLAAAFGP AGMGMGGGAGGAGAGGGGAGVLGQGGGGNGGSGNGGGGSSSGSSGSKSNKSRKEKRAA QQQQQQQQNLANSLNAAAAAAAAAAANNPAAALASMHGFGVGVPGTSIPSVSTGSGSI STNSGGHGSYKSTASAYGKPSTMTSSSMANNPGSAYDPVTLHKELLAMQAVAAAASGS GSSGSSGKKSGGGGSSSSSMHSLGMGIGGSGGMMSSGKASTSVSASNSSLGGMHPSLT SSNPLMSPHAGMGSSSSSSSKDRDKNNPSLNALNSLSQFGALGMTPQQSMQAAMNAFA ASTGVSPSATVTSSPHHSSQQQQQMGGNSSTSGSGKSSSKDYMMGTGSEHPSLLGVRL PPDTEIIKYTSSIVGPKIPGTTSRGRKKTISETEQQTTQQQQKQQHQAEQHLLQQQQQ AQKELDSTKNAISSLLAFPGLSPAKRARLEMEYAAMAAAAQQQHQQAQQQHQAQQQLH GMLGAAGIPGMAGLVGLPGMSGNPLDQLSVSKASSSTAPTTSTSSSSAGSNLLNQSNS DRVEVIKLPPTITSNGAYNLSSKGKEVHDLTTDMATNSGGVNLSLKSNAGSSALTPSG AVGSASNPITIDDFDAPLNLSMKPSDKSNSSSSNAAAGGSSSSSAALANLASDYQAAS SGQSGNSLQSLSSITAALGGTGGMPGGSISGSGGTSPAPAGAGSGATGGGSGSGGSGG GSSSYKEGRPRNLGRGVSKPKKNTVASLLAQSRAVGLKPMLATQQLLQQGADIEKIRL ALSEANAHMETSTDSESVAAESGLSESESEDANILNVAELRVPLELGWKRETVIRGLT KQGQIRGEVTYYAPGSTTPLKSNGQVFAILEQQPSNLSRENFSFSARAIVGSFLQPAP PPYANDGEYIRMTDEDVAKRLEDLKVFTRQTLNVEQRIEIAKQQQAMRDAKKLQKEEL ARNKEKARQEKNSKLEQQRKDKELKNQQAVEERKKRQEELDRLKQEELLKKQQEKEKR RQEAILAKEQELQKQKEMLLAAEMERERRRQHMSLIRMLELRRKFEDREKKKHQLVLD RLLLRERRMAERKRDAEILQLIRRPNEDSEMPQELVIPELDRIAGNRLPGQAMADLLM VFEFLHNFGETLGFDMESLPSLQNLHDALMSDSNADAEEELLSVMTHLLVCAIEDPGV PNPGRHTTLLGQSLRNADITNSNVSEILRIYLYATATGEVRQMHGITVDRERERRVPD HHQLDSDTTTHSHSVKNQEYYKLLHENDTWKLSQSLKDRPFVALNPTRKAQMLAHLCN DLLMNKAVLRQIDGSLETCAQMRKEKYMTDMKVRKYKALHMRKARIEAYERAQAEREA AMQALMAQQKLDAERLKAEEEAKAAAAEEAAAAAGTDGEATKGGSPNGEKPEDGDQNE EGAAKEPQQQQQQPMEVDGVVDEASLVSPAKTIIQTDNSLTPSKQDMPTPTYQINGSS TPTTSGVTGGDMNVLLQAKKSGARNSINDEHHHDVSIIDDDLSDLDSEITNVEEDEDN RLSADELQKKLDKIVRASLNCKEALEKSTNQLRAACFGQDRFWRRYWKLPKAGGIFIE ALESAQNDICDYHEALEAMDDKKDANDEKENSENEKDVAAESSEQPMEVDESITKLED GVPASDVGMPESNQQNAHQDEEDDDDDVTEINKVEPEIVDLGDDDDDAAPPLPKIEPP RPEIKVKSEMELMGPPPTTMISTKTDFEAEIKIPSMPGILMPPTLNNNNTNNNNNNNG SDNCDKLETGLGLGQQQQNFSQSVIKTEDVKKEDDCIIVSTSSVDDTPKWFSIVRREV PLISELPAEEGGVVGQELQISYANQNCSAQLQLQGHPWDLINNMQYYSIPMDECKVDT SKLGNECIFSLSGLDEKQMLAKVEEYKAHKVESKNGLGSPHRHHETKDDEEQAKLKLD KEIDTEMETDADDLAGKEKFFRLRSDVPPDTGGGVSEGTDVKPKIELRLDEALSQAYY HNIANMSLSSVQTYIPIDIPLPLSMTPDEHRLLEQVKLAGFPERVHGVYVPRRQRYGW WQLDDEQKLRQLLKTLNPSGLRERELQENLQRFLGLEQPLGVNYKLKSDIDFPEEFLM PDKKGDWNPKVAKRVELALIEQLESLEDKVASASMQLKNWQLPNRVESELTLDSQEDV TEEDFVSIIPMIRERIIDLEANIERRYLKPPLGSQTGDAHLAVIAQNQHTTTQTQNSA SAAAYLLQMQQQQQQQQLAQQQQQQQQGSGAGNSLNPSSFNERTMALAAAAAASGPGN ATGVANSAVVAGATPCESGSGEPNSGNASPASNCDSDRDEKVEQIPKGLVQWRDAVSR SHTTAQLAMALYVLESCVAWDKSIMKANCQFCTSGENEDKLLLCDGCDKGYHTYCFKP KMDNIPDGDWYCYECVNKATNERKCIVCGGHRPSPVGKMIYCDLCPRAYHADCYIPPL LKVPRGKWYCHGCISRAPPPKKRSAGGTSGSSSKSRRDRDRESGGSAKRRSDNSKTPA MEHMQQQQMPLAGGDSHHHHHQQPPSLNSSHDESMNSLPAAPLSPAHSVVSATNYDDQ HHANNSVDGSSRFHAHLIPPSNNGTAALLEDVPGGANVMPGVYPVYTPVAAGNFSAGL INQAPVQPAMPFANVVAMSPRAVTPTRTRTPTPTPAPTPPPPPPTPLLMQASPTATAL HVNACQSPPQQQHAQLMTMPSPPAIGVGTATNQMSPPPINIHAIQEAKEKLKQEKKEK HATKKLMKELAVCKTLLGEMELHEDSWPFLLPVNTKQFPTYRKIIKTPMDLSTIKKKL QDLSYKTREDFCVDVRQIFDNCEMFNEDDSPVGKAGHGMRKFFESRWGELTDKHS" ORIGIN 1 atcggtttct ctatcgaagc gttcggacgt cgaaaagata aaccccaatt taaatctaat 61 ccatctgcga gcaaattaaa caacaataat gatagattct taagcggcgc gcacatacgt 121 gtcttattaa tcgattttga tgtttaaaaa ataatataga aagttgaagt gaacttgcaa 181 acctcgcgaa tagctggaaa tttgcgcgtg tgcgggtgga acagtgacac tcgtgtgaaa 241 atcatcgcta aggaaaaggc ggataatata aaggaaaaac gcccgcggcg aaaattattc 301 cattggtgtg agtgtgcaaa aaaaaggaag aaatatcaag agcaaagaag ttcgagaaat 361 tgctaaaaat taagtgtgtt tgtgcttgtg tgagtgggtg acaaatgaat gggcagcaaa 421 aagacgagaa gtcaatcagc gataagcagt ttaaacaaac aaaaaagact cccaacgcat 481 gttacgcaca atagttggtc ctaagaacta ggggattttg aacatgaaca aaaatgccgg 541 cgatggcagc gatggcaaaa actcaaacaa aaactcgaat gcgggagggg gtggtggagc 601 cggggggcca cacgacccca ccggcctttt agatgcagct tccctgttcg cttactgggg 661 acgtgatcca actggagcgg cggctgcagc ggcttccaat ccgctcttca actcgcagtt 721 caatgccgcc gctgctgccg gattgggttt attgccacaa gctggaggcg cctctgccaa 781 tgaccgttat tccatggcag cagcagcggc ggctgcggcg ggagcccatc accaccagaa 841 cacgatggca gtggccgctt cccaggccgc cagtttggcc ggtttgcatc cagcaagctg 901 gtggtcaatg gcccagttag ctgcccagga ttacttcagt cgcctgcaag cctcgggtct 961 ttcccccttt ccacatcccg atctggcggc tgcctttgga ccagctggga tgggaatggg 1021 cggcggtgct ggtggagcgg gtgctggagg tggtggagca ggtgtactcg gccagggcgg 1081 cggtggaaat ggcggaagtg gcaacggtgg tggtggatcc tcatcgggtt cttccggcag 1141 caagtcaaac aagtcgcgca aggagaagcg agccgcccag cagcaacaac agcaacagca 1201 aaatctggcc aacagtctaa atgcggcagc tgcggcggca gcagcagcag cagccaataa 1261 tccagcagcc gcgctggcca gcatgcatgg ttttggtgta ggagttccgg gcacgagcat 1321 tccgtcggtg agcacaggta gcggatcaat atccacaaat agtggaggtc atggaagtta 1381 caagagcacg gccagcgctt atggtaagcc ctcgactatg acgagcagca gcatggctaa 1441 taatccgggc tctgcctacg atccggtgac cctgcacaag gagctgctgg ccatgcaggc 1501 cgtggcagcc gctgcttccg gctcaggatc aagcggttcc tcaggcaaga agtccggtgg 1561 gggtggctcc tcatcctcct cgatgcacag ccttggaatg ggaattggtg gcagcggtgg 1621 catgatgtcc agtggcaaag cttcgaccag tgtgagcgca agcaattcat cattgggagg 1681 aatgcacccc agtttgacta gcagcaatcc gctgatgtcg ccccatgcgg gcatgggctc 1741 ctcgtcgtca tcatcgagca aggatcgtga caaaaacaat ccctcgctca acgctcttaa 1801 ctcgctctca cagtttggag ccctgggaat gacgccacag cagagcatgc aggcggcaat 1861 gaatgctttt gcagccagca caggagtttc gccatccgcc acggtaacgt cctcgccgca 1921 ccactcttcc cagcagcaac agcaaatggg agggaacagt tccacgtcgg gatcgggcaa 1981 gtccagttcc aaggattaca tgatgggtac tggaagtgag cacccatctc tgcttggagt 2041 tcgtttacca ccggacacgg agataatcaa gtacacgtcc tcgattgtgg gacccaagat 2101 tcctggtact acctcgcgcg gtcgcaaaaa gactatttcc gaaacagaac agcaaacaac 2161 acaacaacaa cagaaacaac aacaccaagc agaacaacac ctactccaac aacagcaaca 2221 agcacaaaaa gagctcgaca gcaccaaaaa tgccatttcc tctctgcttg catttccagg 2281 tctcagtccc gcgaagcggg ctagactcga aatggagtac gcggcgatgg ctgcggccgc 2341 tcaacagcag catcagcagg cacagcagca acaccaggcg cagcagcaac tccacgggat 2401 gctcggagca gccggtatcc cgggaatggc tggactggtc ggtctgcctg gcatgagtgg 2461 caatcccctc gatcagttga gtgtaagcaa ggccagttct tcaacggcgc ccacaaccag 2521 taccagttcc tcctcagcag ggagcaacct gctcaaccag agcaatagtg atcgcgtgga 2581 ggtaatcaaa ctgccaccaa caattacttc aaacggagcc tataatctct caagtaaggg 2641 aaaagaggtg cacgacctca ccaccgacat ggccaccaac tctggcggtg tgaatctcag 2701 cctaaagtcc aatgctggct ccagcgcctt gacgcccagc ggtgccgtcg gatcggccag 2761 caatcccatt accatcgatg actttgacgc accacttaat ctttccatga agccctcgga 2821 taagagcaat agtagctcgt caaatgcagc agcagggggc tcctcctctt ccagcgcagc 2881 gttggctaac ttggcgagcg attatcaggc agcgtccagt gggcaaagcg gtaatagtct 2941 gcagagtttg agctctatta cagctgcttt gggtggaaca ggaggtatgc ctggtggttc 3001 catttccggc agcggaggaa cctctccagc tccagctggt gccggatcag gagccacggg 3061 tggtggttcg ggatctggtg gatccggcgg tggatcgtcc tcttacaaag agggaagacc 3121 tcgtaacctg ggacgcggcg tatccaagcc caagaagaac acggtagctt cgctgttggc 3181 tcaatcccga gctgtgggcc ttaaacctat gctggccacg caacaacttc ttcaacaggg 3241 tgctgatatt gagaaaatcc gcctggcact gagcgaagcg aatgcccata tggaaacttc 3301 tacagattcc gaaagcgtgg cagccgaaag tggtctttcg gagtctgaga gtgaggatgc 3361 caacattctg aatgtagcgg agctaagggt gccacttgaa ttgggctgga aacgggagac 3421 ggtgattcgt ggactgacta agcaagggca gatccgtgga gaggtcacat attatgcacc 3481 aggaagcacg acgccgctaa agagcaacgg acaggttttt gctatcctgg agcagcagcc 3541 atcgaatcta agtcgtgaaa actttagttt ttccgcgcga gccattgttg gttcattcct 3601 gcagcctgca ccaccgccgt acgccaatga tggcgagtac atacggatga cggacgagga 3661 cgtggccaag cggttagagg atctgaaggt cttcacccgc cagactctta acgtggaaca 3721 gcgaattgag atcgccaagc aacagcaggc gatgcgtgat gctaagaagc tgcaaaagga 3781 agaattggcc agaaataagg agaaggcgcg acaggagaag aactccaagt tggagcagca 3841 gcgcaaggac aaggagctca agaatcagca ggctgttgag gagcgcaaaa agcgtcagga 3901 ggagctagat cgccttaagc aagaggaatt gcttaagaag caacaggaga aagaaaagcg 3961 tcgtcaggag gccattttag ctaaggaaca ggaactacag aaacaaaaag agatgctgtt 4021 ggctgccgaa atggaacgag aacgtcgccg ccaacacatg agcctcattc gaatgttgga 4081 gcttcgtcgg aaattcgagg atcgtgaaaa gaagaaacac cagctggttc tagaccgttt 4141 gcttctgcgt gagcgtcgta tggcggagcg aaaacgagat gcggagattc tgcagttgat 4201 aaggcgtccc aatgaggact ccgaaatgcc acaagaattg gtaatccctg aactggatag 4261 gattgccggc aaccgacttc ccggccaggc aatggccgat ttgctcatgg tctttgaatt 4321 cctacataac tttggggaga ctctaggctt tgacatggaa tcactgccgt cgcttcagaa 4381 cctgcacgat gctttaatga gcgatagcaa cgcggatgcg gaagaggagt tgttgtcggt 4441 gatgacgcat ctattggttt gtgccattga ggatccaggt gttcccaatc ccggcagaca 4501 caccacttta ctgggacaat cgctacgcaa tgcggacatc accaactcga atgtatccga 4561 aatcttgagg atttatctgt atgctacggc cacaggtgaa gtgcgtcaaa tgcacggaat 4621 cactgtggat cgtgagcgag agagaagggt gccggatcat catcaactag atagcgatac 4681 cacaacccac tcacattcgg taaagaacca ggagtactat aagcttctcc atgaaaacga 4741 cacctggaag ttgtcgcaat cgctgaaaga tcgccccttc gttgcgttaa atcccacccg 4801 taaagcccaa atgttggccc atctatgcaa cgacctgctc atgaacaagg ccgtgctccg 4861 ccagattgat ggaagtctag aaacgtgcgc ccagatgcga aaggagaaat acatgacgga 4921 catgaaggtg cgcaagtaca aggctctcca catgcgcaag gctcgaattg aggcctatga 4981 acgagcacag gcggagcgtg aggcggctat gcaggcgttg atggcacagc agaagctgga 5041 tgcagaacgt cttaaggcgg aggaggaagc caaggccgcg gcggcagagg aagcagcagc 5101 tgcagcgggc acagatggag aggcaaccaa aggtggctca cccaatggcg agaagccgga 5161 agacggcgat cagaatgaag agggagccgc caaggaaccc cagcagcagc aacagcagcc 5221 aatggaagtg gatggcgtgg tcgatgaggc atctcttgta agtccggcca aaaccatcat 5281 tcaaacggac aatagtctga cgcccagtaa acaggacatg cccacaccca cctaccaaat 5341 taatggatcc agcacaccta ccacaagtgg tgtcactgga ggcgacatga atgttctgct 5401 gcaggccaag aaaagcgggg cccgaaactc catcaacgat gaacaccacc atgatgttag 5461 tattatcgac gatgatcttt ccgacttgga ttcggagatc acgaatgtcg aggaggacga 5521 ggacaatcgc ttgagtgccg atgagttgca aaagaagctc gacaagattg tcagagcttc 5581 cctaaactgc aaggaggcac tggagaagag cacaaatcag ttgagagctg cgtgctttgg 5641 gcaggatcgc ttctggcgtc gctactggaa gttgcccaag gctggaggta ttttcattga 5701 agcacttgag tcggcccaaa atgatatttg cgattatcat gaggcattgg aggccatgga 5761 tgacaaaaag gatgcaaacg acgagaaaga gaactccgaa aatgagaagg atgttgcagc 5821 ggagtccagt gagcagccaa tggaagtgga tgagtccatt acaaaactgg aagatggtgt 5881 accagcttcg gacgtcggga tgcctgaaag taatcaacag aacgcacatc aagatgagga 5941 agatgacgat gatgatgtga cagaaatcaa caaggtggaa ccggaaattg ttgatttggg 6001 tgatgatgac gatgatgcag ctcccccgct gcccaagata gaacctccca ggccagagat 6061 taaagttaaa tcagagatgg agctgatggg tccaccaccc acgactatga tatccactaa 6121 gacagacttt gaagctgaaa ttaaaatacc ctctatgcct ggcatcttga tgccgcctac 6181 cctcaacaac aacaacacca ataataacaa taacaacaat ggaagcgaca actgtgataa 6241 gttggaaact ggtttgggac taggacagca gcagcagaac tttagccagt ctgtgatcaa 6301 gacggaggat gtgaaaaaag aggatgattg cataatagtt tctacatcca gtgttgacga 6361 tacaccaaag tggttctcca ttgtccggcg ggaggttcca ttgatcagcg aactgccagc 6421 ggaggaggga ggcgtggtgg gccaggaact tcagatcagc tatgcaaatc agaactgctc 6481 cgctcagctg cagctgcaag gtcatccgtg ggatctgatc aacaacatgc agtactactc 6541 gattccgatg gacgaatgca aggtggacac cagcaagctg ggcaacgagt gcatcttctc 6601 gctgagtggc ctcgatgaaa agcaaatgct agccaaggtg gaggagtaca aggcccacaa 6661 ggtggagtca aaaaacggtc tgggctctcc tcatcgccac cacgagacta aagatgatga 6721 ggagcaggcc aagctgaagt tggacaagga gattgacacc gaaatggaaa cagatgcaga 6781 tgacctagct ggcaaggaaa agttttttcg cttgcgctct gatgtacccc cggatacggg 6841 aggaggggtc agcgagggaa ccgatgtaaa gcccaagatt gagcttcgtt tggatgaggc 6901 gttgtcacag gcatattacc acaacatagc caacatgtca ttgagcagtg ttcaaacgta 6961 tatacccatc gatatccctc tgccgctttc catgaccccc gatgagcatc gtctgctgga 7021 gcaggtcaag ctggcaggtt ttccggaacg agttcacgga gtttacgtgc cccgcagaca 7081 gcgctacggc tggtggcagt tggacgatga acagaagctg cgccagctgc tcaaaactct 7141 caatccgtcg ggattgaggg agcgtgaact gcaggagaat cttcaacgat tcctcggact 7201 ggaacagcca ttgggtgtga attataagct gaaatcggac atcgattttc cagaggaatt 7261 cctaatgcct gacaagaagg gcgattggaa tcccaaggtg gccaaacgtg tggagcttgc 7321 ccttatcgaa caactagaat cactggagga caaggtggcc agcgcttcta tgcaattaaa 7381 gaactggcaa ttgcccaacc gcgtggagag tgaactcacc ttggactcgc aggaggatgt 7441 caccgaagag gacttcgtca gcatcatacc catgatccga gagagaatca tcgacttgga 7501 ggcaaatatc gaaagacgtt acttgaagcc gcctttgggc tcgcagacag gcgatgccca 7561 tttggcggtt attgctcaga accagcatac caccacccag acgcagaact ctgcatcggc 7621 agcagcatat ctcctgcaga tgcaacagca gcagcagcaa cagcagttgg cccagcagca 7681 gcagcaacag caacagggtt cgggtgcggg aaatagcctg aatccctcat ccttcaacga 7741 gcgtactatg gcattggcgg cggcagcagc tgcttcgggg ccaggaaacg caaccggagt 7801 agccaactcg gcagtcgtgg caggagccac gccctgcgaa tcgggcagcg gagaaccgaa 7861 ttccggcaac gcgtcaccgg ccagcaactg tgacagcgat cgggacgaga aggtggagca 7921 gatacccaag ggattggtgc agtggcggga cgcagtatcc cgatcgcaca ccaccgccca 7981 gctggcgatg gccctgtacg ttctggaatc ctgcgtggct tgggacaaga gcattatgaa 8041 agcgaattgc cagttctgca cgtccggcga aaacgaggac aagttgctac tgtgcgacgg 8101 ctgtgacaag ggctatcaca cctattgctt caagcccaag atggacaaca ttcccgatgg 8161 cgattggtac tgctacgagt gcgtgaacaa ggccaccaat gagcgcaagt gcatcgtttg 8221 cggcggtcat cgtccgtcgc ccgtggggaa gatgatctac tgtgacttgt gtcctcgtgc 8281 ctaccacgcc gattgctata taccgccgct gctaaaggta ccgcgtggca agtggtactg 8341 ccacggttgc atctcccggg cgcctccgcc gaagaaaaga agtgcaggtg gaacatccgg 8401 cagcagcagc aaatctagga gggacaggga tagggagtcg ggcggatcgg ccaagcggcg 8461 tagcgacaac agcaagacac cagccatgga gcacatgcag cagcagcaga tgccactggc 8521 aggcggggat tcccaccatc atcatcatca gcagccgccg tcgctgaact cctcgcacga 8581 tgagtcgatg aattctctgc cggcggctcc tctgagtccg gcgcactcgg tggtctcggc 8641 cacgaactac gatgaccagc accatgccaa caactcggtc gatggcagca gtcgcttcca 8701 cgcgcatctc attcccccgt caaataatgg cactgcggct ctgctggaag atgtgccggg 8761 tggcgccaat gtgatgcccg gcgtctatcc agtttatacg ccagttgcgg ctggcaactt 8821 ctcagccgga ttgattaacc aagcgccggt gcagccagcg atgccgtttg ccaacgtggt 8881 cgccatgtcg ccacgggctg tcacgcccac ccgcacccga acgcccacac cgacgccagc 8941 acccactccg ccaccaccac cgccgacacc gctgctaatg caggcctcgc ccacagccac 9001 cgccctccat gtaaacgcct gccagtcacc gccccaacaa cagcatgcgc agctgatgac 9061 catgccctcg ccaccagcca ttggagtcgg aacggccact aaccaaatgt cgccaccgcc 9121 catcaacata catgccattc aggaagccaa ggagaagctg aagcaggaga agaaggagaa 9181 gcacgccacc aagaagctca tgaaggagct ggctgtctgc aagacgctat tgggggaaat 9241 ggagcttcat gaggactcgt ggccatttct tttgccagta aacaccaagc agtttcccac 9301 atatcgaaaa ataatcaaaa ctcccatgga cttgtccaca atcaaaaaga aattgcaaga 9361 tttgagctac aaaacccgtg aggacttctg cgtggacgtg cgtcagatct tcgataattg 9421 cgagatgttt aacgaggacg attcgcccgt tggcaaggca ggccacggca tgcgcaagtt 9481 cttcgagtcc cgctggggtg aactgactga caagcactcc tgatcctgca ccactagcca 9541 gccacagatc cagatggcta ccagcaccag cagcacgatc accattggca ccaccgtcac 9601 accgaacaac atggccgtca cagcaacgca tcccattgaa atggtcaccc tggtcgcggc 9661 aacgcaggag gatgaggagg cagccgtgga gacgacaaca gcattaactg aagcagcaca 9721 attttggtca agagattagt ttagattaag cagagattgt acataaatgg gaggaatgag 9781 gagagggtcg agaagcacag catacacatt aatatatata tatatatatt tatatatagt 9841 agatatataa acacacacgc gagagtattc aacgtcctac gtcggtaaag accttggaaa 9901 ggggtagctt tgattaaatt aaatcaccag ccaaggcgaa caacagcgca agtatgcaag 9961 tgaaaaagtg tattcagatt ttaagtatcc aaggcggcag cggcagcagc agtatataaa 10021 caataactat tagccgacat aaactagcag ttagaaatcg tatcgcataa gaagccatct 10081 acagtagacg cccggactgg atgaacgctg acaaatgaca aatgaacacg tacaaaaact 10141 gtctaccaat ttccgatccg atcgatcgat ccatcgtttg aacagtattt tgtgcacaaa 10201 gccgcgtcgc tttattttct acacttacaa ttcgaaccct aattttaaca actatttttt 10261 aagcaccaac gaagcgctca tttaagtttt aaagtgtatt ttgtacttat agcaactccg 10321 aaatctgtat ttaaacgtat tataacaagt gctaacagtt gcccaggcaa aaatgcgaac 10381 aattatactc aaaaaggcgg tgcgaggagg acttgtaaat gtaaatgaaa gcaaattaaa 10441 attaaatgta ttaaattatt tattctgtgt //