Dbfetch
LOCUS NM_057694 5696 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster clathrin heavy chain, transcript variant A (Chc), mRNA. ACCESSION NM_057694 VERSION NM_057694.3 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 5696) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 5696) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 5696) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 5696) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 5696) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 5696) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 5696) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 5696) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 5696) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 5696) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 5696) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 5696) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 5696) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 5696) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 5696) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 5696) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 5696) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 5696) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 5696) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 5696) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 5696) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 5696) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 5696) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jul 15, 2014 this sequence version replaced NM_057694.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..5696 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..5696 /gene="Chc" /locus_tag="Dmel_CG9012" /gene_synonym="CG9012; chc; CHC; chc1; Cla; Clh; CLH; D-Chc; dCHC; Dmel\CG9012; l(1)13Fb; l(1)G0438; l(1)VI" /note="Clathrin heavy chain" /map="13F5-13F7" /db_xref="FLYBASE:FBgn0000319" /db_xref="GeneID:32537" CDS 374..5410 /gene="Chc" /locus_tag="Dmel_CG9012" /gene_synonym="CG9012; chc; CHC; chc1; Cla; Clh; CLH; D-Chc; dCHC; Dmel\CG9012; l(1)13Fb; l(1)G0438; l(1)VI" /note="CG9012 gene product from transcript CG9012-RA; CG9012-PA; Chc-PA; clathrin heavy-chain; clathrin heavy chain; clathrin hc" /codon_start=1 /product="clathrin heavy chain, isoform A" /protein_id="NP_477042.1" /db_xref="FLYBASE:FBpp0073966" /db_xref="GeneID:32537" /db_xref="FLYBASE:FBgn0000319" /translation="MTQPLPIRFQEHLQLTNVGINANSFSFSTLTMESDKFICVREKV NDTAQVVIIDMNDATNPTRRPISADSAIMNPASKVIALKAQKTLQIFNIEMKSKMKAH TMNEDVVFWKWISLNTLALVTETSVFHWSMEGDSMPQKMFDRHSSLNGCQIINYRCNA SQQWLLLVGISALPSRVAGAMQLYSVERKVSQAIEGHAASFATFKIDANKEPTTLFCF AVRTATGGKLHIIEVGAPPNGNQPFAKKAVDVFFPPEAQNDFPVAMQVSAKYDTIYLI TKYGYIHLYDMETATCIYMNRISADTIFVTAPHEASGGIIGVNRKGQVLSVTVDEEQI IPYINTVLQNPDLALRMAVRNNLAGAEDLFVRKFNKLFTAGQYAEAAKVAALAPKAIL RTPQTIQRFQQVQTPAGSTTPPLLQYFGILLDQGKLNKFESLELCRPVLLQGKKQLCE KWLKEEKLECSEELGDLVKASDLTLALSIYLRANVPNKVIQCFAETGQFQKIVLYAKK VNYTPDYVFLLRSVMRSNPEQGAGFASMLVAEEEPLADINQIVDIFMEHSMVQQCTAF LLDALKHNRPAEGALQTRLLEMNLMSAPQVADAILGNAMFTHYDRAHIAQLCEKAGLL QRALEHYTDLYDIKRAVVHTHMLNAEWLVSFFGTLSVEDSLECLKAMLTANLRQNLQI CVQIATKYHEQLTNKALIDLFEGFKSYDGLFYFLSSIVNFSQDPEVHFKYIQAACKTN QIKEVERICRESNCYNPERVKNFLKEAKLTDQLPLIIVCDRFDFVHDLVLYLYRNNLQ KYIEIYVQKVNPSRLPVVVGGLLDVDCSEDIIKNLILVVKGQFSTDELVEEVEKRNRL KLLLPWLESRVHEGCVEPATHNALAKIYIDSNNNPERYLKENQYYDSRVVGRYCEKRD PHLACVAYERGLCDRELIAVCNENSLFKSEARYLVGRRDAELWAEVLSESNPYKRQLI DQVVQTALSETQDPDDISVTVKAFMTADLPNELIELLEKIILDSSVFSDHRNLQNLLI LTAIKADRTRVMDYINRLENYDAPDIANIAISNQLYEEAFAIFKKFDVNTSAIQVLID QVNNLERANEFAERCNEPAVWSQLAKAQLQQGLVKEAIDSYIKADDPSAYVDVVDVAS KVESWDDLVRYLQMARKKARESYIESELIYAYARTGRLADLEEFISGPNHADIQKIGN RCFSDGMYDAAKLLYNNVSNFARLAITLVYLKEFQGAVDSARKANSTRTWKEVCFACV DAEEFRLAQMCGLHIVVHADELEDLINYYQNRGYFDELIALLESALGLERAHMGMFTE LAILYSKFKPSKMREHLELFWSRVNIPKVLRAAESAHLWSELVFLYDKYEEYDNAVLA MMAHPTEAWREGHFKDIITKVANIELYYKAIEFYLDFKPLLLNDMLLVLAPRMDHTRA VSYFSKTGYLPLVKPYLRSVQSLNNKAINEALNGLLIDEEDYQGLRNSIDGFDNFDNI ALAQKLEKHELTEFRRIAAYLYKGNNRWKQSVELCKKDKLYKDAMEYAAESCKQDIAE ELLGWFLERDAYDCFAACLYQCYDLLRPDVILELAWKHKIVDFAMPYLIQVLREYTTK VDKLELNEAQREKEDDSTEHKNIIQMEPQLMITAGPAMGIPPQYAQNYPPGAATVTAA GGRNMGYPYL" ORIGIN 1 atatcggcat taattgtata actttcacac ctctaccttg tcttgcagtc agtatttagt 61 caaacaaaag aaaaataaac tacatttgtt agagcttgat aagagctcag tttgtcttca 121 gtgtgtgtgc ccgtcatcta gcaacaaacc gacgtgatta tttcgactaa acgttccaat 181 ggaaaccgaa tcttaaacca gaaaccgact aaactcgaac gcaattaaac aacaataaat 241 cctcgaaaca aatcaaatac aaactgttac caagtgtgca attcaagaaa acatcgtatt 301 ggcattgttt tcgcaaagat acatttacgt tgtaaaggtc tgtcaataac tagacctcac 361 tgtagtagta aagatgacgc aaccactgcc catccgcttt caggagcatt tacagctcac 421 aaatgtcggg atcaacgcca attcattttc attcagcacg ctcacgatgg aatcggataa 481 gtttatttgc gtgcgggaga aggtgaatga taccgcccaa gtggtcatca ttgacatgaa 541 cgatgccacc aatcccacgc ggcgtcccat ctcagcggat tcggctatca tgaatccagc 601 tagcaaggtc attgcgctca aagcgcaaaa gacgttgcag atcttcaaca ttgagatgaa 661 gtcgaagatg aaggcgcata ccatgaacga ggatgtggtg ttctggaagt ggatctccct 721 caatacgcta gctctggtca cagaaacgag tgtgttccat tggtccatgg agggcgattc 781 gatgccgcaa aagatgtttg accggcattc atcgctgaac ggttgtcaaa tcatcaacta 841 ccgctgcaat gcctcccagc agtggctact cttggtcggc atttcggcac tgccaagtcg 901 cgttgccggt gccatgcagt tgtattcggt ggagcgtaag gtgtcccagg cgatcgaggg 961 gcatgcggcc agttttgcca cgtttaaaat cgatgccaac aaggagccga ccacgctgtt 1021 ctgctttgca gttcgtacgg ccactggggg caagcttcat attatcgaag ttggtgctcc 1081 gccgaacggc aatcagccgt ttgccaagaa ggctgtcgat gtcttctttc cgccggaagc 1141 acaaaatgat ttccctgtgg ctatgcaagt ctctgccaag tacgacacca tctacttgat 1201 aaccaagtat ggatacatac atctgtatga catggagacg gccacgtgca tatacatgaa 1261 tcgtatatcg gccgatacga tctttgttac cgcaccgcat gaggcaagtg gtggcatcat 1321 tggcgtcaat cgcaagggac aggtcctctc cgtgaccgtc gacgaggagc agatcattcc 1381 ctacatcaac accgttctgc agaatcccga tttggccctt cgcatggccg tgcgcaacaa 1441 tttggctggt gccgaagatc tctttgtgcg aaagttcaac aagctcttta cagccggcca 1501 gtatgctgaa gcggctaaag ttgctgccct ggcacccaag gccattctgc gtacgccaca 1561 gacgatccag cgtttccaac aggtgcagac accagctggc tccacgactc cgccgctgct 1621 gcaatacttt ggcattctcc tcgaccaggg caagctgaac aagttcgagt ctctcgagct 1681 gtgccgtccc gtcttgctgc agggcaagaa gcagctgtgc gagaagtggc tgaaggagga 1741 gaagttggaa tgcagcgagg agttgggtga tctggtcaag gcctccgatc ttacacttgc 1801 cctgtccatc tatctgcgcg caaatgtgcc caacaaggtt atccaatgct ttgctgagac 1861 tgggcagttc cagaagattg tactctacgc caagaaggtc aactatacgc ccgattacgt 1921 gttcctgctg cgctccgtga tgcgaagcaa cccggagcaa ggagctggtt tcgcctctat 1981 gttggtggcc gaggaagagc cactggcgga catcaatcag attgtggaca tcttcatgga 2041 gcactccatg gtgcagcagt gcactgcatt cctgctggac gccctcaagc ataaccgtcc 2101 cgccgagggt gccctccaga cgcgcctgct ggaaatgaat ctgatgtctg ctccgcaggt 2161 ggccgacgcc atcctgggca atgctatgtt cacccactac gatcgggccc acattgccca 2221 gctgtgcgag aaggctggac tgctccagcg cgccctcgag cactacacgg atctgtatga 2281 cattaagcgg gccgttgtgc acacgcacat gctgaatgcc gaatggctgg tcagtttctt 2341 tggcacgctg tcggtggagg actcgctgga atgtctgaag gcaatgctta cggcgaattt 2401 gcgccagaac ttgcagatct gtgtgcagat tgccaccaag tatcacgaac agctgaccaa 2461 caaggcactg attgatctgt tcgaaggttt caagagctac gacggactgt tctacttcct 2521 gagcagcatt gtcaacttct cacaggatcc cgaagtgcac ttcaaataca ttcaggcggc 2581 atgcaagact aatcagatta aggaggtgga gcgaatttgc cgtgaatcaa actgctacaa 2641 tcccgaacgg gtgaagaact tcttgaagga ggccaagctg acggatcagc taccattaat 2701 tattgtttgt gatcgttttg atttcgtgca cgacttggtg ctttacctgt atcgtaacaa 2761 tctgcagaag tacattgaga tctatgtgca gaaagtgaat ccatcccgct tgccagtggt 2821 agtgggtggt cttcttgatg ttgattgcag tgaggatata attaaaaatc taattctcgt 2881 ggtcaaggga caattctcaa ccgacgaact ggtcgaggag gtcgagaagc gcaaccgtct 2941 caagcttctc cttccctggc tggagtcccg agttcacgag ggctgcgtcg agccagccac 3001 ccacaacgcg ttggccaaga tctacattga ctcgaacaac aatcccgaga gatatcttaa 3061 ggagaatcag tactacgata gccgtgtggt cggtcgctac tgcgagaagc gggatcccca 3121 tttggcgtgt gtcgcctacg agcgtggatt gtgcgatcgc gagctgatcg ccgtttgtaa 3181 cgagaattct ctgttcaaga gcgaagcacg ctacttggtt ggtcgccgcg acgccgaact 3241 ctgggccgag gtcctttcgg agagcaatcc atacaagcgc cagttgatcg atcaggtggt 3301 acagaccgct ttgtccgaga cccaggatcc cgatgacatc tctgtaacgg tcaaagcatt 3361 catgaccgcc gatttgccca atgagctgat cgaacttctc gagaagatta ttctggactc 3421 gtccgtcttt agcgaccatc gcaatctgca aaacttgctc attctcacag ccatcaaggc 3481 tgatcgcacc cgagtcatgg actacattaa ccggctggag aactacgatg caccggacat 3541 cgcgaacatt gcgatcagta atcagttgta cgaagaagcc ttcgccatct tcaagaagtt 3601 cgatgtgaac acatcggcca ttcaggtgct catcgatcaa gtgaacaacc tggagcgggc 3661 taacgagttc gccgagcggt gcaatgagcc ggccgtttgg tcgcagctgg ccaaggccca 3721 actgcagcag ggtctggtca aggaggctat cgactcgtac atcaaggctg atgatccgag 3781 cgcttacgtc gatgtcgtcg atgtggccag caaggtggag tcttgggatg acctcgttcg 3841 ctatctgcaa atggcacgca agaaggcgcg cgaatcttac atcgagagcg aattgatcta 3901 tgcctatgcg cgcactggac gtctggccga tctggaggag ttcatttcgg gtcccaacca 3961 tgccgatatc cagaagattg gcaaccgttg cttcagcgac ggcatgtacg atgcagcgaa 4021 gctactgtac aacaatgtga gcaactttgc ccgtctggcc atcactttgg tctacctgaa 4081 ggagttccaa ggggccgtgg actcggcgcg gaaagccaac tcaacgcgca catggaagga 4141 ggtgtgcttc gcctgcgtgg acgccgagga gtttaggcta gctcagatgt gcggcctgca 4201 cattgtggtg catgccgatg agctagagga tctgattaac tactatcaaa accgtggata 4261 cttcgatgaa ttgattgcgc tactcgagtc ggctttgggg ctggaacgtg cgcacatggg 4321 aatgttcacc gaattagcta tactttattc aaaattcaaa ccttccaaaa tgcgcgaaca 4381 cttggagctg ttctggtctc gcgttaacat tccaaaagtt ctgcgtgccg ctgaatcggc 4441 tcacttgtgg tcggagctgg tgttcctgta cgataagtac gaggagtacg ataacgccgt 4501 cctggccatg atggctcatc ccacggaggc gtggcgcgag gggcacttta aggacattat 4561 caccaaggta gccaacattg agctgtacta caaggctatc gaattctatt tggacttcaa 4621 gccgctgctg ttgaacgaca tgctgctcgt gctggcaccc aggatggatc acactcgtgc 4681 tgttagttac ttctccaaaa ccggctattt gccactcgtc aagccttatc tgcgttcagt 4741 ccaatctctc aataacaagg caatcaacga agccctgaac ggactcttaa tcgacgagga 4801 ggactaccag ggtctgcgca attcgatcga tggatttgat aactttgaca acattgcgtt 4861 ggcacagaaa ctcgaaaagc acgaacttac cgaattccgt aggattgccg cctacttgta 4921 caagggaaat aatcgctgga aacagagcgt tgagctctgc aaaaaggata aactctacaa 4981 ggatgctatg gagtacgccg ccgaatcttg caagcaagat attgccgaag agttgttggg 5041 ttggttccta gaacgtgacg cttacgattg ttttgcagct tgtctttatc agtgttacga 5101 cttgctgcgc cctgatgtta tcttggagtt ggcctggaaa cacaaaatcg ttgactttgc 5161 catgccctat ttgattcagg ttctgcgcga atacacaaca aaggtggaca aactggagtt 5221 gaacgaggct cagcgcgaga aggaggacga ttccactgag cacaaaaaca ttattcagat 5281 ggagccacaa ctgatgatca ccgctggccc agcaatgggc attcctccac aatatgcaca 5341 gaattatcca cctggtgcag caacggtaac ggcggcagga ggacgcaaca tgggctatcc 5401 ctacttgtag gacttgcgcc cgataatgag atcatcaaaa caactttaaa aacaaatgta 5461 tcagcattaa aggaatacca ataaaataag aaaaataatc tattaattgc atgtgcgcca 5521 aaaattacca aaacgaaaca acacagtaaa cataactttg aacatcatta tattaaagca 5581 atgcaattaa caatccaatt tttggtttgt ttgtagacag ttaaaaattg attatatgtt 5641 ttgataatta cagcactctt tattcaaata taacagaata tattactttt tatcat //