Dbfetch
LOCUS NM_057400 5184 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster spineless (ss), transcript variant A, mRNA. ACCESSION NM_057400 VERSION NM_057400.4 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 5184) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 5184) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 5184) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 5184) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 5184) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 5184) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 5184) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 5184) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 5184) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 5184) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 5184) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 5184) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 5184) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 5184) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 5184) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 5184) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 5184) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 5184) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 5184) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 5184) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 5184) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 5184) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 5184) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 24 (bases 1 to 5184) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Dec 17, 2009 this sequence version replaced NM_057400.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..5184 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="3R" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..5184 /gene="ss" /locus_tag="Dmel_CG6993" /gene_synonym="AhR; AHR; CG6993; dAHR; Dmel\CG6993; Ss; SS; ssa" /note="spineless" /map="89B14-89B15" /db_xref="FLYBASE:FBgn0003513" /db_xref="GeneID:41988" CDS 738..3392 /gene="ss" /locus_tag="Dmel_CG6993" /gene_synonym="AhR; AHR; CG6993; dAHR; Dmel\CG6993; Ss; SS; ssa" /note="CG6993 gene product from transcript CG6993-RA; CG6993-PA; ss-PA; spineless-aristapedia" /codon_start=1 /product="spineless, isoform A" /protein_id="NP_476748.1" /db_xref="FLYBASE:FBpp0082768" /db_xref="GeneID:41988" /db_xref="FLYBASE:FBgn0003513" /translation="MSQLGTVYATKRRRRNGKSLKPPPKDGVTKSNPSKRHRERLNAE LDLLASLLPFEQNILSKLDRLSILRLSVSYLRTKSYFQVVMHKDKEDNGVLPHIHAHD GYRTRELGAFEHGLLDGDMFLQALNGFLMILTCEGEVFFATHSIESYLGFHQSDIVHQ SVYELVHSEDREELQRQLLWNSFLPADMSSMQLAETLAPDKALYLERSFTVRFRCLLD NTSGFLRLDIRGRIKVLHGQNRKTEEPPLALFAYCTPFGPPSLLEIPHKENMFKSKHK LDFSLVSMDQRGKHILGYADAELVNMGGYDLVHYDDLAYVASAHQELLKTGASGMIAY RYQKKDGEWQWLQTSSRLVYKNSKPDFVICTHRQLMDEEGHDLLGKRTMDFKVSYLDT GLASTYFSEADQLVVPPSTSPTAHALPPPVTPTRPNRRYKTQLRDFLSTCRSKRKLQQ QNQPQTQQTSPLGGQVGSPAPAVAVEYLPDPAAAVAAAYSNLNPMYTTSPYASAADNL YMGSSMPANAFYPVSENLFHQYRLQGAVGGYYTDYPHSGAPASAYVANGFLSYDGYAI ASKADEKWQETGKYYSGYSSGYGSPTSTPQVRKQIPLKTPKSSPQVMEVISCSSDGPS PVGGATPNGVGSVTPKVELAGTTAAAAAGQDPYERQTVLMWGTTHSSGVPLNSHGGRT GAGNPASPQRSTPLGNGLGYASANNNNNDLEPATAAKWNGTKELPGKSGSASTPESYQ MQHDDSGLYSASSHTTSPQQQQQQQLQQSQRGVGSNVSAPSSSLTSTGTDQQAVHPSS CHQQQQQQQQQHHHAHPHPHSHHHHHHHHHHETAHQHSSEVWTPASYTQYSQYFTYHH PHPHPHHPSAGGGGHVPAQSHHLHHGHR" ORIGIN 1 gttggaatct caaagcgttt acgtggccgc agcgcagcag agtcacgttt gaaagagtgc 61 gagtgagaga tagcgactta gagcaccgcg ccgagtgcga gtgagagagc gcgctccatc 121 gcctttgtgc ctcgtttcaa atgcccgttt gtccgttttt ttggcactgt tgttcattca 181 ttcactcgct tctggcgctc gcgtgcagtt gcagtcgctg ctccctccta acggttgttt 241 cgccgtcgcc agaatcccgc taaaaggtgc gtgcgtgttt gtgtgtgcct ctaaccaact 301 gaaactacag tgcaatatac acaaaaaaat aaaaaacaaa aacaaaagga gcgcgagaaa 361 tgaaaaagca aacaaaatgt aagcgtgatg ataattaaaa ataaatacaa agaagaaaaa 421 aacgaaattt acgcgtggct acaactccga aaccgaaaac cgcagcagga tctcagcgga 481 tctgatcgca ctcagctcct ggctgtgtct gtgtgcgagt ccgtgtgtgt gagagtgtgt 541 acccagagca agccaaatca ataaataaaa accaattaca aaaggaaaaa aagcgaaata 601 agaaagccac gacgaggaaa caacctgtac gacagacgag cagaaggcag cagaagacaa 661 caacgaaata ttgatacgaa aaataataag agttaaaatc attcacgacg gcgaccataa 721 cgaactccgc cctagcaatg agccagctgg gcaccgtcta cgccaccaag cgaaggcgac 781 gcaacggcaa gagcctgaag ccgccgccca aggatggcgt cacaaagagc aatccatcaa 841 agcggcatcg ggagcgcctc aacgccgagc tggatctgct ggcctcgctg ctccccttcg 901 agcagaacat cttgagcaaa ctggatcgac tgagcattct aaggctgtct gttagttatt 961 taagaaccaa aagttatttt caagttgtta tgcataagga taaggaggat aacggagtcc 1021 tgccccacat acacgcacat gacggctaca ggacacgaga actaggcgcc ttcgagcacg 1081 gcctgttgga tggtgatatg ttcctccagg ccctaaatgg atttctaatg atactgacat 1141 gcgaaggcga agtcttcttt gccacgcaca gcatcgagag ctatttgggt tttcatcagt 1201 cggacatcgt ccaccagtcg gtgtacgaac tggtgcactc ggaggaccgc gaggagctgc 1261 agcgccagct gctgtggaac agtttcctgc ccgccgacat gtccagcatg cagctggcgg 1321 agaccctggc gccggacaag gcgctctacc tggagcgcag cttcaccgtc cgcttccgct 1381 gcctgctgga caacacgagc ggcttcctgc gcctggacat ccgtggccgc atcaaggtcc 1441 tgcatggcca gaaccgcaag acggaggagc caccgctggc cctctttgcc tactgcacgc 1501 ccttcgggcc gcccagcctg ctggaaatcc cgcacaagga gaacatgttc aagtccaagc 1561 acaagctgga cttctccctg gtatcaatgg accagcgcgg caagcacatc ctgggctacg 1621 cggacgccga gctggtcaac atgggcggct acgatctggt gcactacgat gaccttgcct 1681 atgtggccag cgcccatcag gagcttttga agacgggtgc ctctggcatg atcgcctacc 1741 gttaccaaaa gaaggatggc gagtggcaat ggctgcagac gagctcgcgc ctggtctaca 1801 agaactccaa gccggacttt gtgatctgta cgcaccgcca gctgatggac gaggagggcc 1861 acgatctgct gggcaagcgc accatggact ttaaggtcag ctacctggac acgggactgg 1921 cgtccaccta cttctccgag gcggaccagc tggtagtgcc tccgagcacc tcccccacgg 1981 cccacgctct gccgccgccg gtgacgccaa cgcgtccaaa tcgccgctac aagacgcagt 2041 tgcgcgactt cctttccact tgtcgcagca aacgcaagct ccagcagcag aaccaaccac 2101 agacgcagca aacctcacca cttggtggcc aggtgggatc ccctgctccg gctgtagccg 2161 tggagtactt gcccgatccg gcagctgcag tggccgctgc ctactccaac ctaaatccca 2221 tgtacacaac ctcgccgtat gccagtgccg cggacaatct atacatgggt agctccatgc 2281 cggccaacgc cttctaccca gtcagcgaga acctcttcca tcagtaccgg ctgcagggcg 2341 ccgtcggtgg ctactacacg gattatcccc actccggcgc tccagcctca gcttacgtag 2401 ctaatggatt tctctcttac gacggatacg ccattgcttc caaagcggac gaaaagtggc 2461 aagagactgg aaagtactac agtggctaca gcagtggcta tggaagtcca acatctacgc 2521 cacaggtacg aaaacaaatt cctctgaaga cgccgaaatc ttcaccccag gtgatggagg 2581 tgatatcttg ctcctcggac ggtccatcac ctgtgggcgg agccacgccc aacggagtcg 2641 gaagcgttac ccccaaagtt gagttggccg gaacaacggc ggcagcagca gcgggtcaag 2701 atccctacga gcgtcaaacg gtgctgatgt ggggcaccac gcactcgagt ggggtaccgc 2761 taaatagtca tggcggtcga actggagccg gaaaccctgc ctcaccacag cgatccactc 2821 ctcttggcaa cggattgggc tacgcaagcg ccaataataa caacaacgat cttgaacctg 2881 ccacggctgc caagtggaac ggaacaaagg agctgccggg caagtcgggc agtgccagta 2941 cgccggagag ctaccagatg cagcatgatg attccggcct ttactccgcc tcttcgcaca 3001 caacctctcc gcagcagcaa caacagcagc agctccaaca atcacagcga ggagttggtt 3061 ccaatgttag cgctcccagc agctcactca ctagcacggg cacagatcag caggcggtgc 3121 acccatccag ttgccatcaa caacagcagc agcagcagca acaacaccat cacgcccacc 3181 cgcatccgca ctcgcatcat caccaccatc atcaccatca ccatgagacg gcgcatcagc 3241 acagcagcga ggtatggacg cccgcctcct acacgcagta ctcgcagtac ttcacgtacc 3301 atcatccgca tccgcaccca caccatccgt cggctggcgg cggtggccat gttccggccc 3361 agtcgcatca cctgcaccac ggccaccgct agaagacgaa tagattgcac cagtaatgaa 3421 gcacccgcac tctctgtact cacccacaac cactcacctt cttctgaaac caatagaaac 3481 ccacttcagt gcacccaagt gtgctctctc gcctgactac taaccataac gatcctccct 3541 agatcattct caccacccat catcagcaac agtcgcagca gcagcagcaa tcgctcgctg 3601 gctacccgct gcaccaccag ctggtgggag ttggatcagg atcaccgccg ccgcagccgc 3661 cagtcgcatt gtcccgctcg cccacgacct tgccggcggt cagcagcttg ctgaatggat 3721 cggcttcagc aggaggagca tcggatattc cataccagca attggccatt gtgtccgctc 3781 ctctggtgat ttgcgccgag gaggtgggtg gaggcgtcag cagcattggc cgcaagtcat 3841 ccaagcagca acagtccctg caacacctgc agcagcaaca gtcactgcaa cagcagcaac 3901 atgcaattta tcagcagcaa catcaccact cgcagcatca tccgcatcat cagctgctct 3961 atccggcgaa cattacggcg cacaccgcgc tggcttatgc cccgcccacg gccggaggcg 4021 catatgccga tggcagtccg ctgctctcct tctccgaggt gaccaacacg ctactgaacc 4081 agtgaatgtg cagggaggag gcggggaagg gaaccgttca acagttttgc caaaatgtgg 4141 actatgacta tcgtatcttc cataatctga accagcaacg aatggatata gccagcgcac 4201 gccattcgtc cacccactcc ttggttgatt ctcagaaaac tgcagcagcc gcagcagaaa 4261 taatttctat ttattttact gtgataattt atagatacat tgtattgtat gtgaaactag 4321 gtttgcccgt caacaaaaaa tccaaaacag ccgtatccaa tcttccaggg aatcgggtat 4381 gggtactgca accttaatca gcacaaagtt acgaagccaa tccccgttga tcccaagcaa 4441 tcatgatggg tagatggcgg ttagcatcga catttaattt cagttgtaga tacaaccaaa 4501 gatttctcta acttatactt atcgttttag cataatacga tccatccaat tggcttcggt 4561 ttgtagcgcc aaactttagt tacattttag ttacactcgt gatcggagtg agaaataaat 4621 gcctaaacag ttgcgattaa gagtgcttaa gtagcattta agtgaataac agatgcttgt 4681 atccatattt aattgaactt tagacgtaac gagtattgca agataaagta attttcatga 4741 ttcctatcgt ttagcaagta actaaattaa tccgtaagcg gatatacccg catacatata 4801 ttgtattgta tgtttaaagt tttcttggaa tttctagtcg cccgcataaa aacatttact 4861 tataaactaa aaaaatacaa gagataccaa ttgatggtag atttatgtat aatattttgc 4921 aattcggcag gcattactgt aggtagtctg tactaccgac tattggtaac cagcaatgta 4981 tgagctatcc aacattacag cttaagcatt gatgattgat catgtattca aaaacatata 5041 tttaaattgt agataatctg tcagctaata aacgaaatat ttaataaaat ctcaattata 5101 aatttataaa agaatcccga gtgcacgtaa agcgcgccta tccaaaacaa tcagagcgaa 5161 ataaatctag aaaataatcg aatc //