Dbfetch

LOCUS       NM_001275519            3752 bp    mRNA    linear   INV 26-DEC-2023
DEFINITION  Drosophila melanogaster fragile X messenger ribonucleoprotein 1,
            transcript variant I (Fmr1), mRNA.
ACCESSION   NM_001275519
VERSION     NM_001275519.1
DBLINK      BioProject: PRJNA164
            BioSample: SAMN02803731
KEYWORDS    RefSeq.
SOURCE      Drosophila melanogaster (fruit fly)
  ORGANISM  Drosophila melanogaster
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
REFERENCE   1  (bases 1 to 3752)
  AUTHORS   Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St
            Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K.,
            Strelets,V., Russo,S.M. and Gelbart,W.M.
  CONSRTM   FlyBase Consortium
  TITLE     Gene Model Annotations for Drosophila melanogaster: Impact of
            High-Throughput Data
  JOURNAL   G3 (Bethesda) 5 (8), 1721-1736 (2015)
   PUBMED   26109357
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3752)
  AUTHORS   Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St
            Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B.,
            Russo,S.M. and Gelbart,W.M.
  CONSRTM   FlyBase Consortium
  TITLE     Gene Model Annotations for Drosophila melanogaster: The
            Rule-Benders
  JOURNAL   G3 (Bethesda) 5 (8), 1737-1749 (2015)
   PUBMED   26109356
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3752)
  AUTHORS   Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I.,
            Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R.,
            Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G.,
            Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N.,
            Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A.,
            Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E.
  TITLE     The Release 6 reference sequence of the Drosophila melanogaster
            genome
  JOURNAL   Genome Res 25 (3), 445-458 (2015)
   PUBMED   25589440
REFERENCE   4  (bases 1 to 3752)
  AUTHORS   Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M.,
            Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F.,
            Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E.
  TITLE     Sequence finishing and mapping of Drosophila melanogaster
            heterochromatin
  JOURNAL   Science 316 (5831), 1625-1628 (2007)
   PUBMED   17569867
REFERENCE   5  (bases 1 to 3752)
  AUTHORS   Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H.
  TITLE     The Release 5.1 annotation of Drosophila melanogaster
            heterochromatin
  JOURNAL   Science 316 (5831), 1586-1591 (2007)
   PUBMED   17569856
  REMARK    Erratum:[Science. 2007 Sep 7;317(5843):1325]
REFERENCE   6  (bases 1 to 3752)
  AUTHORS   Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D.,
            Ashburner,M. and Anxolabehere,D.
  TITLE     Combined evidence annotation of transposable elements in genome
            sequences
  JOURNAL   PLoS Comput Biol 1 (2), 166-175 (2005)
   PUBMED   16110336
REFERENCE   7  (bases 1 to 3752)
  AUTHORS   Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A.,
            Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A.,
            Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W.,
            Celniker,S.E., Rubin,G.M. and Karpen,G.H.
  TITLE     Heterochromatic sequences in a Drosophila whole-genome shotgun
            assembly
  JOURNAL   Genome Biol 3 (12), RESEARCH0085 (2002)
   PUBMED   12537574
REFERENCE   8  (bases 1 to 3752)
  AUTHORS   Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J.,
            Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E.,
            Rubin,G.M., Ashburner,M. and Celniker,S.E.
  TITLE     The transposable elements of the Drosophila melanogaster
            euchromatin: a genomics perspective
  JOURNAL   Genome Biol 3 (12), RESEARCH0084 (2002)
   PUBMED   12537573
REFERENCE   9  (bases 1 to 3752)
  AUTHORS   Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S.,
            Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E.,
            Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L.,
            Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D.,
            Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J.,
            Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M.,
            Rubin,G.M. and Lewis,S.E.
  TITLE     Annotation of the Drosophila melanogaster euchromatic genome: a
            systematic review
  JOURNAL   Genome Biol 3 (12), RESEARCH0083 (2002)
   PUBMED   12537572
REFERENCE   10 (bases 1 to 3752)
  AUTHORS   Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W.,
            Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E.,
            Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M.,
            Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S.,
            Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M.,
            Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W.,
            Gibbs,R.A. and Rubin,G.M.
  TITLE     Finishing a whole-genome shotgun: release 3 of the Drosophila
            melanogaster euchromatic genome sequence
  JOURNAL   Genome Biol 3 (12), RESEARCH0079 (2002)
   PUBMED   12537568
REFERENCE   11 (bases 1 to 3752)
  AUTHORS   Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D.,
            Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F.,
            George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N.,
            Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X.,
            Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D.,
            Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L.,
            Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D.,
            Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M.,
            Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S.,
            Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P.,
            Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A.,
            Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B.,
            Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I.,
            Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S.,
            Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C.,
            Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S.,
            Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z.,
            Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J.,
            Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J.,
            Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z.,
            Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C.,
            Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A.,
            Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C.,
            McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C.,
            Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L.,
            Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K.,
            Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S.,
            Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K.,
            Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I.,
            Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C.,
            Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R.,
            Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A.,
            Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT,
            Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F.,
            Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H.,
            Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O.,
            Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C.
  TITLE     The genome sequence of Drosophila melanogaster
  JOURNAL   Science 287 (5461), 2185-2195 (2000)
   PUBMED   10731132
REFERENCE   12 (bases 1 to 3752)
  AUTHORS   Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R.,
            Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R.,
            Smith,E., Yu,C. and Rubin,G.
  CONSRTM   Berkeley Drosophila Genome Project
  TITLE     Drosophila melanogaster release 4 sequence
  JOURNAL   Unpublished
REFERENCE   13 (bases 1 to 3752)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-DEC-2023) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   14 (bases 1 to 3752)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (13-DEC-2023) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   15 (bases 1 to 3752)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2022) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   16 (bases 1 to 3752)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2020) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   17 (bases 1 to 3752)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (22-APR-2019) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   18 (bases 1 to 3752)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAY-2018) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   19 (bases 1 to 3752)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (07-DEC-2016) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   20 (bases 1 to 3752)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2015) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   21 (bases 1 to 3752)
  AUTHORS   Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R.,
            Park,S., Svirskas,R. and Karpen,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2006) Berkeley Drosophila Genome Project,
            Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne
            Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA
  REMARK    Direct Submission
REFERENCE   22 (bases 1 to 3752)
  AUTHORS   Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S.,
            Svirskas,R. and Rubin,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2006) Berkeley Drosophila Genome Project,
            Lawrence Berkeley National Laboratory, One Cyclotron Road, MS
            64-121, Berkeley, CA 94720, USA
  REMARK    Direct Submission
REFERENCE   23 (bases 1 to 3752)
  AUTHORS   Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H.
  CONSRTM   Drosophila Heterochromatin Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project,
            Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron
            Road, Mailstop 64-121, Berkeley, CA 94720, USA
REFERENCE   24 (bases 1 to 3752)
  AUTHORS   Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive,
            Rockville, MD 20850, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by FlyBase. This
            record is derived from an annotated genomic sequence (NT_033777).
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: FlyBase
            Annotation Status   :: Full annotation
            Annotation Version  :: Release 6.54
            URL                 :: http://flybase.org
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3752
                     /organism="Drosophila melanogaster"
                     /mol_type="mRNA"
                     /db_xref="taxon:7227"
                     /chromosome="3R"
                     /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2]
                     bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]"
     gene            1..3752
                     /gene="Fmr1"
                     /locus_tag="Dmel_CG6203"
                     /gene_synonym="AT24755; BcDNA:GM08679; cg6203; CG6203;
                     dfmr; dFMR; Dfmr; dfmr1; dFmr1; dFMR1; DFmr1; dFmrp;
                     dFMRP; DFMRP; dfxr; dFXR; dfxr1; dFXR1; dFXRP;
                     Dmel\CG6203; dmfr1; EP(3)3517; fmr; FMR; fmr1; FMR1; Fmrp;
                     FMRp; FMRP; FXR"
                     /note="Fragile X messenger ribonucleoprotein 1"
                     /map="85F10-85F12"
                     /db_xref="FLYBASE:FBgn0028734"
                     /db_xref="GeneID:37528"
     CDS             177..2096
                     /gene="Fmr1"
                     /locus_tag="Dmel_CG6203"
                     /gene_synonym="AT24755; BcDNA:GM08679; cg6203; CG6203;
                     dfmr; dFMR; Dfmr; dfmr1; dFmr1; dFMR1; DFmr1; dFmrp;
                     dFMRP; DFMRP; dfxr; dFXR; dfxr1; dFXR1; dFXRP;
                     Dmel\CG6203; dmfr1; EP(3)3517; fmr; FMR; fmr1; FMR1; Fmrp;
                     FMRp; FMRP; FXR"
                     /note="CG6203 gene product from transcript CG6203-RI;
                     CG6203-PI; Fmr1-PI; fragile X mental retardation protein;
                     fragile X related protein; fragile X mental retardation
                     related 1; fragile x related; fragile X-related;
                     fragile-X; Fragile-X mental retardation 1; fragile X
                     retardation 1 protein; drosophila fragile X mental
                     retardation protein; dFMR; fragile X protein; fragile X
                     mental retardation gene; fragile X mental retardation 1;
                     fragile X mental retardation protein 1; cg 6203 gene
                     product from transcript cg6203-rc; Fragile-X-related;
                     dFmr1; Fragile-X mental retardation protein"
                     /codon_start=1
                     /product="fragile X messenger ribonucleoprotein 1, isoform
                     I"
                     /protein_id="NP_001262448.1"
                     /db_xref="FLYBASE:FBpp0307053"
                     /db_xref="GeneID:37528"
                     /db_xref="FLYBASE:FBgn0028734"
                     /translation="MKYPFVNVRLPPEETVEVAAPIFEEGMEVEVFTRTNDRETCGWW
                     VGIIKMRKAEIYAVAYIGFETSYTEICELGRLRAKNSNPPITAKTFYQFTLPVPEELR
                     EEAQKDGIHKEFQRTIDAGVCNYSRDLDALIVISKFEHTQKRASMLKDMHFRNLSQKV
                     MLLKRTEEAARQLETTKLMSRGNYVEEFRVRDDLMGLAIGSHGSNIQAARTVDGVTNI
                     ELEEKSCTFKISGETEESVQRARAMLEYAEEFFQVPRELVGKVIGKNGRIIQEIVDKS
                     GVFRIKVSADQNIPRELAHVPFVFIGTVESIANAKVLLEYHLSHLKEVEQLRQEKMEI
                     DQQLRAIQESSMGSTQSFPVTRRSERGYSSDIESVRSMRGGGGGQRGRVRGRGGGGPG
                     GGNGLNQRYHNNRRDEDDYNSRGDHQRDQQRGYNDRGGGDNTGSYRGGGGGAGGPGNN
                     RRGGINRRPPRNDQQNGRDYQHHNHTTEEVRETREMSSVERADSNSSYEGSSRRRRRQ
                     KNNNGPSNTNGAVANNNNKPQSAQQPQQQQPPAPGNKAALNAGDASKQNSGNANAAGG
                     ASKPKDASRNGDKQQAGTQQQQPSQVQQQQAAQQQQPKPRRNKNRSNNHTDQPSGQQQ
                     LAENVKKEGLVNGTS"
ORIGIN      
        1 ttcggttttg ttgttttgat gatttccctt tcttgtcgtt gcaatttata aagataagat
       61 ccgattaaac catcttatat cgcggttaag tgattttcgc ggatagatta cagggccagg
      121 tgacagctgt cgccgatgat ggcatctttg tggatgtgga cggcgtgccc gagagtatga
      181 aatatccatt tgtgaacgtt cgcctgccgc ccgaggaaac cgttgaggtg gccgcaccga
      241 tcttcgagga gggcatggaa gtggaggtgt tcacgcgcac gaacgatcgg gaaacctgcg
      301 gctggtgggt gggcattatt aaaatgcgca aagcggaaat ctatgcggtc gcgtacatcg
      361 gttttgagac gtcctacacc gaaatctgtg aattgggtcg tctgcgcgcc aaaaactcga
      421 atccgccaat tacagccaag accttctacc agttcacgct gcccgtgccc gaggagttgc
      481 gcgaagaagc ccagaaggat ggtatacaca aggagtttca gcgcacaatc gatgccggcg
      541 tgtgcaacta cagtcgcgat ctggacgccc tgattgtcat ctccaagttt gagcacactc
      601 agaagcgagc cagtatgctc aaggatatgc attttcgtaa tctctcacaa aaggttatgc
      661 tgttgaaaag gactgaagaa gctgcccgtc agctcgaaac aactaaactg atgagccgtg
      721 gaaactacgt tgaggagttc cgtgtgcgtg acgatctcat gggtttggcg attggctcgc
      781 atggctcgaa tattcaagcg gcacgcactg tggacggcgt caccaacatc gagctggagg
      841 agaagtcctg cacattcaaa atcagcggag agaccgagga gtctgtgcag cgtgcccgcg
      901 cgatgctcga atacgccgag gagttcttcc aggtgcccag ggagttggtg ggcaaggtga
      961 ttggcaagaa tgggcgcatt atccaggaga ttgtggacaa gagtggcgtg tttcgaatca
     1021 aggtgagtgc tgatcagaac ataccacgtg agctggcgca tgtacccttt gtgttcattg
     1081 gcaccgtgga gagcattgca aatgccaaag tgctgttgga gtatcatctg tcgcacctga
     1141 aggaagtaga acagttgcgt caggagaaga tggagattga tcagcagctt cgcgccatcc
     1201 aggaatcctc catgggctcc acacagagct tcccagtgac gcggcgctct gagcgcggct
     1261 acagcagtga cattgagtcg gtgcgctcta tgcgcggcgg tggtggcggc cagcgtggtc
     1321 gtgtacgcgg acgtggtggt ggcggtcctg gaggtggcaa tggcctgaac cagcgctacc
     1381 acaacaatcg ccgcgacgag gatgactaca actcgcgggg cgatcatcag cgtgaccagc
     1441 agcgtggcta caacgatcgc ggcggtggtg acaacactgg cagctatcgt ggaggcggtg
     1501 gtggcgccgg tggtcctggc aacaacaggc gcggcggaat caaccgccgg ccgccacgca
     1561 acgatcagca gaatggcagg gactatcagc accacaacca caccaccgaa gaggtgcggg
     1621 agacccgtga aatgagcagc gtggagagag cggacagtaa ctcatcgtac gaaggtagct
     1681 cgcggaggcg cagaaggcag aagaacaaca atggacccag taacacaaac ggagctgttg
     1741 ccaataacaa caacaaacct cagtcggcgc agcagccaca acagcagcag ccgccggcgc
     1801 ctgggaataa ggcggcacta aatgccggag atgccagcaa acagaacagc ggcaatgcga
     1861 acgccgctgg cggtgcgagc aagccgaagg atgcctcacg caacggcgac aagcagcagg
     1921 cgggcacaca gcagcaacag ccatcgcagg tacaacagca gcaggcggca cagcagcagc
     1981 agccgaaacc gcgacgcaac aagaatcgca gcaacaacca cacggaccag ccatccggac
     2041 agcagcagct ggcggagaat gtcaaaaagg agggcctggt caatggcacg tcctaagccg
     2101 agtggccaaa gcggtaggag gagcaacagc tcacagatgg ctagaacaac atgaacacga
     2161 attgcacatc gttcgacgga gtaacaatgt tgtatgcgca gcggggcagt ttaataatca
     2221 tgttgatgtc cttgaatgta gccgccacat aacacaacaa ccaacaacaa ccacacaaca
     2281 caacacaact caacaacaaa caaaacatcc gatcaacatc agacactaga acaacatcat
     2341 cagccaacaa caagctccac taaccaattg tttgagaaac tataagagta actaaaaaaa
     2401 taggaatcga aaaattatat acatgaaata tgtaacaaat gtgaaagcat atactaacac
     2461 acacacacac tcacacaagg atacactcac acacaaccac acacacaata cagttcgaat
     2521 tatacacaaa aaggaggaag taataaaaga aaattcatgc ctaggcttat aatttgaatt
     2581 gaaactaaaa aagcttcaat aacaatcaaa atgaattata tttatgtata aaagaaactc
     2641 aaaggcaatt attaacaagc aaaacgaacg aatcgaaagt gaaacattga atatgtaaac
     2701 taaaacttta actctaatcc gggcaactag gcgtagtttt tcgaaaagaa aatctaaaga
     2761 aaacctgacg aaatgggcgc ttcaaaagcg cccctttgcg tcaacttgaa aagtttctag
     2821 ttatatgcat attataataa aacgagaatg atataattgc atttttgttt tggttaaatt
     2881 aattttagtt gtgtctgtca tgtgtttgtt tttgtgtata attcgtgcat gcaacaactt
     2941 aatcgcctag caggtttttc tacattatca ttatttttgt attattatat tttagtttac
     3001 taatgtaaat gcccaggcgc gtttagaagt tgcttataaa tttcgaaagc cacggcgaac
     3061 aatttcattt gcaggtgaat gtctgcaaag gacttgttcg tcgtgagctt ttgcatcgtt
     3121 tcattgtttc attgtttatt ttgttcgtta caacatggaa atcctctctt aattgtataa
     3181 ttttgtattt atttactatt attaacacat cccacacacc acacacgcca cactcacccg
     3241 catacacgaa tatcaattct cacacacacg agctcgctca tacaaaacag aagggaaacg
     3301 cattaatttt gattttgttt tataaatata taatttactt cgccaaacct acaaagcgta
     3361 tactaactta gtcctctatt aaatactctt aaattattta aaacaagtaa aacgtgccga
     3421 gtcgggagag gagcattgaa cacaatcatc gagtgacgcg aatcatttca attgaatcat
     3481 aatagaagac ccaactatgg aatataaata cacaatgtaa agccaccata aagaaaccat
     3541 ctaagaacaa atagcaagaa gcagaacaga acaattcttt cctcttattt ggaagaacag
     3601 tgtcaataat atgtaagaaa ggcaaaccac acattttaac atacattaaa gaaggagata
     3661 acgataatgg taccgataaa gataaatcta aataatgttg tgtaattcaa attaaaacaa
     3721 ataaaacaaa aatccaacta aatggaaacg gc
//