Dbfetch
LOCUS NM_001274207 8360 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster plexus (px), transcript variant E, mRNA. ACCESSION NM_001274207 VERSION NM_001274207.1 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 8360) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 8360) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 8360) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 8360) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 8360) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 8360) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 8360) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 8360) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 8360) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 8360) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 8360) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 8360) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 8360) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 8360) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 8360) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 8360) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 8360) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 8360) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 8360) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 8360) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 8360) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 8360) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 8360) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 24 (bases 1 to 8360) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..8360 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="2R" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..8360 /gene="px" /locus_tag="Dmel_CG4444" /gene_synonym="CG4444; Dmel\CG4444; l(2)k08134; l(2)k08316; PX" /note="plexus" /map="58E4-58E8" /db_xref="FLYBASE:FBgn0003175" /db_xref="GeneID:37573" CDS 576..6326 /gene="px" /locus_tag="Dmel_CG4444" /gene_synonym="CG4444; Dmel\CG4444; l(2)k08134; l(2)k08316; PX" /note="CG4444 gene product from transcript CG4444-RE; CG4444-PE; px-PE" /codon_start=1 /product="plexus, isoform E" /protein_id="NP_001261136.1" /db_xref="FLYBASE:FBpp0304275" /db_xref="GeneID:37573" /db_xref="FLYBASE:FBgn0003175" /translation="MEKAKAYIKNELRGGSQQSEPATTPNPTSPASAPGTPQATRHSY PPVELMPSPGAAAHRSARTPGEQYHFGYQAHPAQHYHSGAKSTGRASAPPDNHHVPMT ICFVCGGHGSFEPQPLRIRHNAERPSESYFPFLERHEPPNGVPGVVPGQEYVWACMLC FRSLNEQWDAYERQKKPLLQRIYHMKRVDGKGYIGADVATQSEYAAQVLGLSAEHLTQ NGLVEGHGDPYALARHYSPQQPSHHHHSTSRNASPSPNPIAAVGGGGEFYPRNSTPSS NHNRYLSRPQSRDMPVASPTSRPPSEPPAMKSAGYAQQKFKLSPAPPVGYQGQAPYHP AQYQQLQQQTAAYHLLQQQVNAGGGATESAHYKGNPYGALPSPGSGPLGPRAASTLED DNATVLDLRNSSNSSAPPAPRHVGSTASSVSQPSQPQSEVGILDLSMPDKNSITEVCY VCGDEQRRGSLIELSTVKPRETGRPGPSVPYFPLFNEQHPRPARSRPKDPRGMIQACL PCYEDLMQQWNVHQASHKPESERSYLLRKRSTPAAERTTFVCYTCGTDTPSSQLRLVY CCPNAEREPYYPFIKTMKVYKNASPISPQGMVQVCSTCNEKHSGLAEGGPPPASSSIH SAVGGGSPSAGHSLESNSAMYSTSGAITGNSGAQFGGRNSPSEKSLANSDSMSNVRFR PYETNSNNSNSNTARDLKQIRRSDSRPNSPSSSQGAIENGHGQYPCSICKVLCPSNKM DWLSTSAEHMNSHAMHFPCLKANAVTNNNNNNNNTNNNNNNNNNELNSNRVLACKDCK DYLASQWETMDAERVPLEHRRYNIPSPMLTSSSPNGSRHGAMSINTPPSTPSISSSTP ASTSIYCYLCGLHSDLTLARVLYASKEGSRPYFPLLLKHNSLPNAEQLRNNSALVCTF CYHSMLNQWRKYEAQSPSVNPADRKYNWHDYNCHLCGITTYRKRVRALPVNEFPFVKH QKSDDGLLLENGEYAVVCLDCYESLRQQASQHDRFGVPISRRAYNWVPQPPPPEDSPE SAVARLPCGERSDRIHINNALRPVPGKKTTSPKQYDKSKEVPPKAGQKRPATSPAPHI PVPHHLQTPPGGGAGGLPGSSVANSPIPSSAGGNALMNHALPNNHIGTPSPQQQHQHQ QHQQQQQQQQHQAQQQAQQQAVAAAVQQQLAAGVGLPPGAIGAASASSRGSFAAALRT LAKQADIKEEDVGGDRSVPTSGAGGPPPSSSGPGSLNSVAGRVGSERPGEDRVSSNKK RSPPSPQPPEKIARLSHTPQTASLQPELLARSGFQPYRSDERLMHPAGAFPLEAYSHF AGLQGIPPAFLNPAGLPYTEQLYLEHRYQLFRAAGAHPSHPHAAALYPQMASPYSHLY SMMPGAALGISPAMHDRMKLEEEHRARLAREEEREREIQREKERELREQREKEQREKE QREKEQREREQREKEQREKEARERKLRDEERERERERQQLLTASHHYSNQLYSPLNRN LLGSMIPHLNMSLRGPPGALHGLPGMSHYHAAAANAQRQSPHGAMGLNLGMAGLPGVP PLGGHGPNLQHHLQQAAMGLAHPGAAGLTHPGFSAAALGLGAHPHSLNLSHPHMSPHH PASLAHQLPPHTSSAGGGGLSNSIPVTASSSLSASSPHTSLNLTSSVKLSADQVPTST PSGGVSGSGMPPTTSSSHIPNMGHYYHHGHLAAMHAAAAAASGMTPTAAHQQQPLSLP SSPKITPPITPSSSANGGRAGGSPHAMRHHIAAAVAAAAQQSAMIDKAATPVTHEPTT LDLTGSNSNSSNQAPSNASSGQPTNHEVNGAESNGASQTESKEHLAIKEDGHKSSPPP VALEKKPATPNAAADKPIHPDSSPENSSRRSASPQSDANNSLPAVSVTAAASDDTKPQ LGGLGRSNSAEEATAL" ORIGIN 1 gcgcagtgtg cacacactgg cagccactgc tggttggctc ttcttcttgc aactgctgca 61 attatatatc gctgttccgt cgtctccgcc gatccaactc cgcgcaaaaa accgcacata 121 tatcgctcaa cggtccgcga ataatccgta aatattgcaa ttgcacgatt gttcagccac 181 aactgaaaca taaaatcgaa accctatttt taccagctta acatgggtaa agtgaaactt 241 ataagaaaac catgaagaat accgtgaatg ctcaattcaa aatttgaaaa tccactagtg 301 ctcttaatag cttcaaaagc aagtgaagaa atttagaata aagagtgtga taaccgaaag 361 aaacaccgag aaacgccgag gaaagtctag acaagtgcct gaaaccaaat gtgtttgccc 421 cgaagttaag tcccttcgat ccgcccaaat cggctttaat tcccgtaaat cccctcttcc 481 gcccaataat tccgccacaa aaacaggcac atgagttgga ttaatcggag tcaactggaa 541 taggccgaag cacccggagc acagctgcta gtactatgga aaaggcgaag gcgtacatca 601 aaaatgaact tcgcggtggc agccagcaat ccgagccagc aaccacgccg aacccgacct 661 caccggcctc ggcgcctgga acaccccaag cgaccaggca ctcctatccg cccgtggagc 721 tgatgccctc acccggagcg gcagcccatc gaagcgcccg gactccgggc gagcagtacc 781 actttggcta tcaggcgcat cccgctcagc attaccattc gggcgccaag tcaacgggca 841 gagcctcggc accacccgac aaccatcatg tgcccatgac catatgcttt gtgtgcggcg 901 gacatggcag ctttgagccg cagcccctga ggattcgcca caatgcggaa cggccttcag 961 agtcgtattt cccatttctg gagcgtcacg agccaccgaa tggtgtgcct ggtgtggtgc 1021 ccggccagga gtatgtgtgg gcctgcatgc tttgctttcg atccttgaac gagcaatggg 1081 atgcctacga gcgacagaag aagcccctgc tgcagcgcat ctaccacatg aagcgggtgg 1141 acggcaaggg ctacataggt gccgatgtgg ccacccaaag cgagtacgcc gcccaggtgc 1201 tgggcctgag tgccgagcat cttacccaga atggtctggt ggaggggcac ggagatccct 1261 acgccctggc acgccactac tcgccgcagc agccgtcaca ccaccaccac agtacctcta 1321 ggaatgcctc accctcgccg aatcccattg cagccgtggg tggtggtggg gaattttatc 1381 ccaggaattc gacgccgtcg agcaaccaca acagatacct gagcaggccg caatcgcggg 1441 acatgcccgt ggcctcgccc acatcacgac cgcccagcga accaccggcc atgaagtccg 1501 ccggctatgc gcagcaaaag ttcaagctga gtccggcacc gccggttggc tatcaaggcc 1561 aggcgccgta tcatcccgcc cagtaccaac agttgcagca gcagacggct gcctatcatc 1621 tgctgcagca acaggtaaat gctggcggcg gagcaacgga gtcggctcac tacaagggca 1681 atccctacgg tgcgttgccc tcgcctggca gcggtccatt gggccctcgt gctgcgtcaa 1741 cgctcgaaga tgacaatgcc accgtgctcg atctgcggaa ctcctccaat tccagtgctc 1801 cgccagcacc gcggcatgtt ggcagcactg catcctccgt ctctcagcca agtcagccgc 1861 agtcggaggt aggtatactg gacctgtcca tgccggataa gaactccatc accgaggtgt 1921 gctacgtgtg cggcgatgag cagcgcagag gcagcctcat cgagctgagc accgtgaagc 1981 ccagggaaac gggcagaccc ggaccatccg tgccgtactt tccactcttc aacgagcagc 2041 atccgcggcc agcacgttcg cgtcccaagg atccccgcgg catgatccag gcctgtctgc 2101 cctgctacga ggacctcatg cagcagtgga atgtccacca ggcatctcat aaaccggagt 2161 cggagcgatc ttatctcctg agaaaacgct ccacgcccgc ggccgaaaga accactttcg 2221 tttgctacac ctgtggcacg gacacgccct cctcgcaact tcgccttgtc tactgctgcc 2281 cgaatgccga aagggagccc tattatccat tcatcaagac catgaaggtc tacaaaaacg 2341 ctagtccaat tagcccgcaa ggcatggtcc aggtctgctc cacctgcaac gagaagcact 2401 ccggcttggc ggagggcggt ccacctccag cttcatccag catccactcc gcagtgggtg 2461 gaggttcgcc cagtgctggc cactcgctgg aatcgaattc ggccatgtac agcaccagtg 2521 gagcgataac cggaaatagt ggggcacaat ttgggggtcg taactcacca tccgagaaat 2581 ccctggccaa ttcggactcc atgagtaatg tgcgatttag gccctacgag acgaactcga 2641 acaattccaa ctcaaacacg gcacgcgacc tcaaacaaat tcgtcgcagc gattcgcgtc 2701 caaattcgcc gagttccagc caaggagcca tcgaaaatgg acacggccag tatccttgct 2761 ccatttgcaa agtgctgtgc ccctcaaaca aaatggattg gctgtccacc agtgccgagc 2821 atatgaactc ccacgccatg cactttccct gtctcaaggc caacgctgta accaacaaca 2881 acaataataa caataatacc aataacaaca ataataacaa caacaacgaa cttaacagca 2941 atcgcgtgct ggcctgcaag gactgcaagg attacttggc cagccagtgg gagaccatgg 3001 atgcagaacg agttccccta gagcacagaa gatacaacat tccctcgccc atgctgacct 3061 ccagttcacc aaacggatct cgccacggcg ccatgagtat caacactccg ccctccacac 3121 catccatatc gtcctcgacg cctgccagca catcaatcta ctgctatctt tgcggcctgc 3181 actcggacct aacgttagcc agagtgctct atgccagtaa agagggttcg cgtccttatt 3241 tcccactgtt gctcaaacac aattcacttc ccaatgcgga gcagttaagg aacaattcag 3301 cgttagtttg caccttttgt taccattcca tgttgaatca gtggcgaaag tatgaggccc 3361 aaagtcccag cgtcaaccca gcggatcgta aatacaattg gcacgattac aactgtcacc 3421 tgtgcggcat tacgacttat cggaaaagag ttcgggcgtt acccgtcaac gagtttccct 3481 ttgtaaagca ccagaagagc gatgacggcc tgctgctgga aaacggagaa tacgcggtcg 3541 tctgtctgga ctgctacgag agcttaagac aacaagcctc acagcacgat cgctttggag 3601 tgcccatatc caggcgggcc tacaactggg tgccccaacc gcctccgcca gaggacagtc 3661 ccgagtccgc agtggcccgc ttgccctgcg gcgagcgctc cgatcgcatt cacatcaaca 3721 atgccttgcg gcccgtgcca ggaaagaaga ccacatcgcc caaacagtac gacaagtcaa 3781 aagaagtgcc gccaaaggct ggacagaagc ggccagccac cagtccggca ccgcacattc 3841 ccgtgccgca ccacctgcaa actcctcctg gcggcggcgc cggcggcttg ccgggatctt 3901 cggtggcaaa cagcccgatt ccatcgtccg ccggtggcaa cgcccttatg aaccacgccc 3961 tgcccaacaa tcacattggc accccgtcgc cacagcagca gcatcagcac cagcaacatc 4021 aacagcaaca gcaacagcag caacaccaag ctcaacaaca ggcacaacaa caggcggtgg 4081 cggctgcagt gcagcaacag ctggcagccg gagtgggctt gcctccagga gctattggtg 4141 ccgcttcggc cagtagtcga ggctcctttg ccgccgccct gcgaacgctg gccaagcaag 4201 cggacatcaa ggaggaggat gtcggtggag acagaagtgt gccaacttcg ggagccggag 4261 gaccaccgcc gtcgtcaagt ggcccaggat cgctgaattc ggtggcaggc cgcgtgggat 4321 ctgagcgacc tggcgaggat cgagtgtcta gtaacaagaa gcgatcacct ccgtcgccac 4381 agccgccgga gaagatcgcc cgtctgagtc acacgccaca aacagcatcg ctgcaaccgg 4441 aactcttagc caggagcggt ttccagccgt acagatcgga cgagcgattg atgcatccgg 4501 caggtgcctt tccgctggag gcctactctc acttcgccgg attgcagggt attccgccag 4561 cttttctgaa tcccgctggt ctaccgtata cggagcagct ctacttggag catagatacc 4621 aactgtttcg ggccgccggc gcacatccct ctcatccgca tgcggctgcc ctgtatcccc 4681 aaatggcctc gccgtactcc cacctgtact cgatgatgcc gggagcagcg ttgggtatct 4741 cgccagcgat gcacgaccgg atgaagctgg aggaggagca ccgggcgcga ttggcgaggg 4801 aggaggaacg cgaacgagag attcagcgcg aaaaagagcg tgagctgcgg gagcagcgcg 4861 aaaaggagca gcgggaaaaa gagcaacggg aaaaggagca acgtgagcga gagcaacgtg 4921 agaaggagca gcgcgagaag gaggcacggg aacgaaagct gcgggacgag gagcgtgagc 4981 gcgaacggga gcgacagcaa ttgttgactg cctcgcacca ttactcgaat cagttgtact 5041 ccccactgaa ccgaaatcta ttgggttcca tgattccaca tctgaatatg agtttacgag 5101 gacccccagg tgcacttcat ggccttcccg gaatgtcgca ctatcatgca gcggcggcaa 5161 atgcccagcg gcagagtccc catggagcca tgggtcttaa tcttggcatg gctggcctcc 5221 caggcgttcc ccccctcggt ggtcacgggc ctaatctgca gcaccacctg cagcaggcgg 5281 ccatgggctt ggctcatccg ggagccgctg gcctcacgca tcccggcttc tcagccgctg 5341 cccttggact cggcgcgcat ccgcacagtc tgaacctcag ccatccgcat atgtcgccac 5401 accatcccgc ctccctggct caccaattgc caccgcatac ctcttcggcc ggcggagggg 5461 ggctaagcaa ctccataccc gtcacagcta gctccagttt gtctgcgtcc tcaccacaca 5521 ccagcctaaa tctgacatca tctgtaaagc taagcgcgga tcaggtaccc acatcgacgc 5581 ccagcggtgg tgtcagcggc agtggaatgc ctccgactac ctctagttcc cacattccca 5641 acatgggtca ctattaccac cacgggcatt tggcggccat gcatgcggct gcagcggcgg 5701 caagcggaat gactccgacc gctgcccatc aacagcagcc cctgtcgctg cccagctcac 5761 ccaaaatcac gccaccgatc actccatctt cctcggccaa cggaggcaga gcgggcggca 5821 gtccacatgc catgaggcat catattgcgg cagcggtggc tgctgcagcc caacaatcgg 5881 cgatgatcga caaggcagcc acgccggtga cccatgagcc caccaccttg gatttaaccg 5941 ggtcaaattc aaattcgagc aaccaggcgc catctaacgc aagcagtggc cagccgacaa 6001 accacgaagt gaatggagct gaatccaatg gagcgtcgca gacagaaagc aaggagcact 6061 tggcaatcaa agaggatggc cacaaaagtt ctccgccgcc ggtggcgctt gaaaagaagc 6121 cagccacgcc gaatgcagct gcagacaaac ccatccatcc ggacagctcc ccggaaaact 6181 cttcccggcg cagtgccagt ccccaatcgg acgcgaacaa ctcgctgccg gcggtcagtg 6241 ttaccgcagc agcatcagat gacaccaagc cacagttggg cggactgggt cgcagcaata 6301 gtgcggagga ggctacagcc ttatgacacc aactcttcag taattccaat aactaactaa 6361 tgaaaagcta cagcgacatt ggaatgtact tgctgtcgga gcaagctctt caccagcagc 6421 gcaagcggat gctggacgag ttcctgaagc tataatagga ttatcccagg gattagccag 6481 ggacgattgg ccagaaaaaa gcattaggcc gctataaata atacaatgta aattccacaa 6541 cagatatcag atatttgttt tttctcggtg ttacaatcta atgtttaccc aaccagttga 6601 atacaattct accacaatta gacattttga attggtgtaa aattcgtaac tgcataaaat 6661 gtaaaataat gtgacatatt ccaagtaaag taattactct caaacgaaac gttagctgta 6721 agagttttag gtacgtattt gcatgaaact ctggatgtag ttttcgtgtg gcaatgttca 6781 cggcccgaaa atattaatgc tagttgtaaa gttagattaa attctgataa gaaatttata 6841 tatacacaac agaaacagaa attatacaaa catactgggt agctatattt tattcttaaa 6901 ttgctaattg ctaataattg tgatttggag agtacgaata aaaatggaaa acgtatgaac 6961 aagtaactcg aatacaaagt ggggaaaacg gaactgaaat ttagataaca aatcaaatca 7021 aaaacctagg gagatattct ggaatggatt agaagtgaac agcgaaaggc cgaaattatt 7081 tttcgaaatt aaataacttt tgtatgccac cctttggccc ttaaaactct ttgtcttatt 7141 tttgtgattt taaatatttt gtacgcagaa cttagagtgc cgaaatcgga aaacgcattc 7201 gccacaatct tcagaaacac aattccaagc acaagctagc aaatggagac gtactattga 7261 acaagagtac tatgtatccg cactataatt gatgtttata gtaagtagtt aataccctaa 7321 aaccaagcaa actctcaaag atatagacct agttttcatt accgttttta aactttgccc 7381 ctctatcttg cctcctactt ttcctttttt gtgtttgaga ttgcctaaca tttgacggta 7441 cgcaaagtaa cggtttacat atattttaat gcataaatct cgagcaatct gtgatattat 7501 aaaaacaaaa acaaaaatga caaaccaaac caaaactcaa aaatcattgc gtatgagcca 7561 catttgagac cctgtactgc aagatttaaa tcattttcga agcaggacac accagaaagt 7621 taggagtcct tgccgagtat ggacaccgat acgcttcgac atattcgaac aattttcgcc 7681 atatgcaagt cgacttttcc ttttgacaaa actatgtgta tgtaccagta aaactgaaaa 7741 tgaatatatt ttaataacta atcataatag attcttgaat gaaacacata actgaaatcg 7801 attggcgcgc atctagtaac gtaaccacaa atgccatgcg atagctaatt aactactgca 7861 aaatagtttc aaatacaacc ttaacaaaag aaaacaactc gatcgtaaat taattgtatt 7921 gtaactcccc ctcaatcttc gttgtgtgtg taacagaata caaagtgtaa aacattaaac 7981 tgtaagctaa tggaaacaaa atcgaaacca aaaaccaaat acaacagcta ccgaaacaat 8041 agcaatagac ataaagagga acgctccagt ctgtccggaa actgatctta cagccgaatt 8101 cagaatcctg agttagtcct gagctacata taccccatcg gattaagatc aataactcga 8161 cagtcgggcg ctcctttctc ggatcttcac acgaccacac catatagttg ggtatatatc 8221 aacacaatcg cgcagcagaa tagatatgta cgaatgttca accatgtggc aaacgatatg 8281 cgaaacaaac atttaaacaa tattgtgcaa ctttacataa ggcatttatg attttatgaa 8341 ataaactcta cttaaggatg //