Dbfetch
LOCUS NM_001274115 7651 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster muscleblind (mbl), transcript variant P, mRNA. ACCESSION NM_001274115 VERSION NM_001274115.1 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 7651) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 7651) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 7651) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 7651) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 7651) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 7651) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 7651) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 7651) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 7651) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 7651) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 7651) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 7651) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 7651) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 7651) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 7651) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 7651) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 7651) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 7651) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 7651) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 7651) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 7651) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 7651) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 7651) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 24 (bases 1 to 7651) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..7651 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="2R" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..7651 /gene="mbl" /locus_tag="Dmel_CG33197" /gene_synonym="BG01127; CG10941; CG14477; CG33197; chaste; chst; cht; Dmel\CG33197; l(2)01038; l(2)k01212; l(2)k05507; mb1; Mbl; MBL; mbn; mm; n(2)k07110" /note="muscleblind" /map="54A3-54B5" /db_xref="FLYBASE:FBgn0265487" /db_xref="GeneID:36945" CDS 1042..3045 /gene="mbl" /locus_tag="Dmel_CG33197" /gene_synonym="BG01127; CG10941; CG14477; CG33197; chaste; chst; cht; Dmel\CG33197; l(2)01038; l(2)k01212; l(2)k05507; mb1; Mbl; MBL; mbn; mm; n(2)k07110" /note="CG33197 gene product from transcript CG33197-RP; CG33197-PP; mbl-PP; MUSCLEBLIND; chaste; mindmelt; BG01127" /codon_start=1 /product="muscleblind, isoform P" /protein_id="NP_001261044.1" /db_xref="FLYBASE:FBpp0302029" /db_xref="GeneID:36945" /db_xref="FLYBASE:FBgn0265487" /translation="MANVVNMNSLLNGKDSRWLQLEVCREFQRNKCSRQDTECKFAHP PANVEVQNGKVTACYDSIKGRCNRDKPPCKYFHPPQHLKDQLLINGRNHLALKNALMQ QMGIAPGQPVISGQVPAVATNPYLTGIPANSYSPYYTTGHLVPALLGPDPVTSQLGPV VPQTVQVAQQKIPRSDRLETSPLAAHHHQQQQQLQHQLNNINNNNNHSTAGAAATSTT ATTTTNNAAAAAAAAAAAAAAAVMGHHTLEVGKKRAADTTDMFPLQFSGMVPFKRPAA EKSGIPVYQPGATAYQQLMQPYVPVSSSPKIPLNASCVIYTDASGQLLDTLPVCQDFN RSMCSRLNCRFVHLTEDDKVEVIDQRVAVCRDHANSQCRRKQCKYYHIPIVLPPANIM AAMITSPSDQQPAVPVATTTANPAAAAAAAAAATAAGYNGTSNLIIIEPQQQQQQPPQ QQQQFSYHSNSSNNNYYHSNASKQAAHASNMYQQQQQQHQQQQQHQQHLQHQQHAQQQ THITYHCSSPYSPSSASSSSSCSIATSPTLSSATTLSTTSTATMPTPQQQYQGPAATA TFLKAPAYYTDATPTLVLSSDYNSNCIPIQATPFISLQAAPQQHLLKYTTQAPPPQAQ QHAFVGHHYQTQMGQVVATTVAAIPATTITVAPATVASPSTCI" ORIGIN 1 aagaagcgca ctttgattgc aagtgccgcc cgcttgtgcc gccgcttctg cgatatagat 61 tccgattttg ccttcagtct ccagccgact tcctctacgt gcggttctca gtcgtcagtc 121 gccagttgcc agtcgcaaat cgcaaattgc aaattgcaaa tcgccagtcg ccagagttcg 181 tagaattaga attcgttgtc gcgcttgcag ttcgcagttt gctgttccgc tcagcttctc 241 tcagccggga gttatccttt cgtcaccatc tccagaaaac caggtccttt cgcctgttcg 301 cctttcagtt gcgcgcgcga ttttatagcc cgcgatcatt tgcccgatcg agtcaaaaat 361 ctgtgaacaa aaaaaaaaac ggttgaaaag ggttaatcct tttagttttt gtggactttt 421 aagtgacgaa ataaaattga accgagcaag agtgactagt gactagcgca gaaaagctaa 481 aactttatgt aattaaacaa caggcttaca attagactct aaaaaagctt ccttttacgt 541 tccgccaact cttcgtcctt cccttcaatt gcccagataa tgtaaactca gcttacacac 601 aaaaaagcag taaaatataa aatacaaaaa ttaacagctg cgtttatcta tagatatata 661 tatacacatc tatatatttg aataagcgtt cgatttgaat caaaattata gcccaagcta 721 tcagctaccc ccacaagctt tgtactccac aaaaacgcta acgagcaaaa tcgataaaga 781 ccagatagca aatgaaatca taccatctgc catagatcta tgctataaac atatataggt 841 gctgatctgt gctcttgaat ttagtgtttt ttgtgtgtgc gtgtcgcgag aggagcactc 901 aaaaccaaaa aaaaaaaaaa aaacgtatag taaaacaaaa aactatctct agtcgctagg 961 ctataactat acaaactcca gctatcccag atccagatcc gtaaacagca aatagttata 1021 tatctataac cccaaaatac gatggccaac gttgtcaata tgaacagcct gctcaacggc 1081 aaggattcgc gctggctgca attggaggtc tgtcgcgagt tccagcgcaa caaatgctcg 1141 cgccaggaca ccgaatgcaa gttcgcccat cccccggcca acgtggaggt ccagaacggc 1201 aaggtcaccg cctgctacga cagcatcaag ggccgctgta atcgtgataa accgccgtgc 1261 aaatactttc atccaccaca gcatctgaag gatcagttat tgataaatgg acgcaatcat 1321 ttggccctca agaatgcact gatgcaacag atgggcatcg cgcccggcca accggtcata 1381 tcgggccaag tgccagccgt ggcaacaaac ccctatctga ccggcattcc ggccaactcg 1441 tacagtccgt actacacaac gggacacctg gtgcccgcct tgctgggtcc ggatcccgtg 1501 acctcccaac tgggacccgt ggtgccccaa acagtgcagg tggcacagca gaaaatacca 1561 cgttccgaca gattagagac ctcacctctt gcggcacacc atcaccagca acaacaacaa 1621 ttgcaacacc agctgaacaa catcaacaac aacaacaacc acagcaccgc tggcgcagca 1681 gccacctcga caacagcaac aacaaccaca aacaacgccg ctgccgccgc cgccgctgct 1741 gccgccgccg ctgccgccgc tgtcatgggc catcacacac tggaagtggg caagaagcgg 1801 gcggcggaca cgaccgacat gtttccactg caattctctg gcatggtacc gttcaaacgt 1861 ccagctgccg aaaagtctgg cattccagtt tatcagcccg gtgcgaccgc ctatcagcag 1921 ctaatgcagc cctacgtgcc agtctcatcg agtccgaaaa tacccttgaa cgcttcctgt 1981 gtcatctaca cggatgccag tggccagtta ctggacaccc tcccggtgtg ccaagatttt 2041 aatagatcta tgtgcagtcg gttaaattgt agattcgttc atttaactga agatgacaag 2101 gtcgaggtga ttgatcaacg tgttgctgtc tgccgcgatc atgccaacag ccagtgccgc 2161 cgcaagcagt gtaaatacta ccacataccg attgtcctgc cgccggccaa catcatggcg 2221 gccatgatca ccagtcccag tgatcagcag ccagctgtgc cggtggccac aacaacagcc 2281 aatccggcgg cagcggcggc ggcggcagca gcagcaacag cagccggcta caacggcacc 2341 agcaacttga taatcatcga gccgcagcag caacagcaac agccgccgca gcagcagcaa 2401 cagttcagct atcacagcaa cagcagcaat aacaactact accacagcaa tgccagcaag 2461 caggcagcac acgccagcaa catgtatcaa cagcagcagc agcagcatca gcaacagcag 2521 caacatcagc aacatctgca gcatcagcaa cacgcgcagc agcaaacaca catcacctac 2581 cactgcagct cgccctactc cccctcgtcg gcatcctctt catcctcctg ctcgatagcc 2641 acctcgccga ccctctcgtc ggccaccacg ctatccacca cctcgacggc cactatgccc 2701 acgccccagc aacagtatca gggcccggcg gccacggcga cctttctaaa ggcccccgcc 2761 tattataccg atgccacgcc caccctggtg ctgagcagcg actataactc caactgcatc 2821 cccatccagg cgacgccgtt catctcgctg caggctgctc cgcagcaaca tctgctgaag 2881 tacaccaccc aggcaccgcc accgcaggcg cagcagcatg cctttgtggg tcaccactac 2941 cagacgcaga tgggccaggt ggtggccact actgtggcgg ccattccggc caccacgata 3001 acggtggcgc cggcaacagt ggcgtctcca tcgacatgca tctagaagaa gggggtttct 3061 tatctgccgc agggggcagc tctgtttatt ttaccagaga cgtatattag gtcataggga 3121 tgtgtttcct gcgaagtccc tatagatttg aaaacattag ttatggcgcc caaaagtgaa 3181 aagtgaaata tttaaaacta aagagttatt tgagcacttt taattaacat aattttgaaa 3241 tattatcctg ttagccatag gaggaactaa aatgttcatt ttataaagtc tagcatactt 3301 ttaagcacct taattgatgt tttcaaaaac caagaggccc aagaaacaca tcgtataggg 3361 tttttcttta ttaaaagttt gtcacctacc tttatccatt gaatactcgt ttttgtcaac 3421 tccagttcac ctagatactt atattgcata atcctcaaaa cctaagcaac acaatacgta 3481 taccaatcat gaatactccc caagcgatgc tctacacgag actccaagct aaattgaaag 3541 aaatcaaaaa gcaaatgcag aacttgtctg aaaaaggtct aagctagtaa ataaaacttc 3601 aaacaatcac attctacgaa acacaaacac aaagcagtaa tggaagtttt tgatgaaaat 3661 taaaggttga tacgaactat ttacaaaaaa taagaaccga aagtactttt gggggaaagg 3721 agaaaggtaa actcaactga actttttcgt acgtatagca agactttaac gtgtaagcat 3781 ctcatttaca catcaagtga catgcattag agggaaaaca ttgagtgaag actctacaat 3841 attgcaaaac ccaaacagaa gagatgaata atacgagtgt tgttaaatgc gaaaagaaac 3901 taaagaaaat tagcaattaa aaattgaaat taatattaca agagaaagaa ctttggagga 3961 gagcgcagtt gcattaaaat tagttacaaa ctattttaaa ctctagtgtt ccatatttca 4021 atgcaaataa aaaatacaaa taaaagtgaa taaagataaa ggtacattaa agtggataaa 4081 catatagtga ggagtgttaa tattagctaa ggttaagcct gacaaaccgt tctccatggc 4141 aaatagtcaa aattaatcaa aaacagaatc tacataggcc atagataagc agcaagaaca 4201 actaataata aacacttaac aataacaata ataataacga taatgataac gataacgaaa 4261 acgatgagga tgaagatgaa aaaagtacag tcacgtccta tttttgcaac aacgatttac 4321 tacaagcgag aggcaaacga tacggagatt ttattaagca aaatggtcag cagaggtcag 4381 ataaagaaaa cagagtacag aaaccataat ccttttttac attttataat aacgatcaag 4441 ataaatcagc agaactacag caagagaaac catatttttt atatacaatg gaagcatcaa 4501 aaacaacact gataaacaaa atcgatatga ggtaaacaaa caagaaattt aatcaaattt 4561 aaaggaataa gcattttttg caaacaacaa acaaagacgg agactttttt aaagtgtatt 4621 aataacaact tatttagctg aattctctag caaatgaaca caaagaactc taaacaacat 4681 ttaatgagga taaccactca gctcacacag aaatcgaaat tgtaccgtat tatatcttcc 4741 tatgcaaacg atttgtaagc actatatatg tatatagaaa catacccact atatgcgaca 4801 tttacgaatc cagacttatt tccgattaac tgttcgttta cagtttgccg ctgttttaat 4861 gacgttttgt gacttgtttt ttatacactc aagaacgtat ttggaacaca cataataaga 4921 attacattaa attgcagaac ggaaactact tattatatac aaaagcatac gtacatatat 4981 acaccatata tgtatatata ctacatatat ttatgtctgt acacgtatga atatatatac 5041 attaacacaa atatattgat tatatatata catatatata tttactaatg gcaactaaac 5101 atgaaatgtg atcttttaaa gaaacaaaaa gtaaagaaag aaaaataata attaaacgat 5161 ggcaggcaga attggataaa ggtaaaactg aattaaagta aatcgaacta gcagcaatcg 5221 aatactagag ccatggcaag caggatagtt aaacgtaatt ttaaatgggt tccatctcga 5281 ggcaagcgta cgaatatctc cattcaataa ggataacacc aataatactc gacatctagc 5341 taataattgt tcagcaataa cagatatatc tacatataca tttaagggct ggctataata 5401 tacggaaatt tgtttttttt ttcatcgcaa tcacactatc acctatcact atcacctatt 5461 actatctctc aatctcacta ctgtccgtac acctgagttc ctccttttca ataagactcg 5521 gatagcgtat atccagcacc taaacctaac cacttgtagt actcaacttc agctcgctct 5581 cttcgaagcc tcctccaaac ttactcgatc acacggaagt cgtatcccga acttttccgt 5641 actcaaaata agaatgccta ataagtttcc gtccattata atcagacctt aaatctatgt 5701 gcaacgacag cggaagcaga agcaagtgga acagttgtaa acgaataaaa gtaaattaac 5761 taaagtaaac aattaaagta aatgattaat tataaacaca atacacgtag attctcaaac 5821 taaaagctcg tcgacatttt aacagttact aacatttaaa taataataac gacaaatgag 5881 taatacaata agctgcaaaa gggcaaacaa aaaaagggaa accatgatgt tttgtgtaaa 5941 aataaatgtt ctttaaagag aaaaaattta aaaatcgaaa aaaaacacac acacaaaaac 6001 caataaacga aaatgagaaa tcctagttac taagcaaact aactacgaac atatagacac 6061 tatagaatca ttgtaccata agagatttca gcgggatttt gttcaacttg acatcttctc 6121 tagtatgtgt agattggcat gtcatttgac atggccacgc atgtagaata gcacgagttt 6181 gtaaactaga aacgaaactt ttatttgcct taacatcaaa ccaatatata caccaatata 6241 cattgattta aatcttctga atagtttcga attgtttcga aaaccaattt cacttgacgc 6301 atgtacatgg cgctcttaaa acaaacagat acagatacta tatgacagca gaaaataatt 6361 ctgaatcgaa gggaaaacgg attaatgtag ttatgtgtag agtctccttc attgtaagtc 6421 atagttatta ttgttaattt taatttatat ttacacatat atattagatc attatgatta 6481 ttaattgtga atatgatgtg atgtgtttat tgaaagaaaa acaaaaacga aactaaaaca 6541 aaacaaaaca aaatcgaaaa tacaattact gaatgttgca acgtaaagaa aactaaatgt 6601 attgaaccct gagcgaagag tgaagcgaaa ttacaagaaa ccttatcgag aatgtgaggg 6661 aaaatcaatt ttactccact tcggatggtt aagtaagcgt aatgttaaat tacactatga 6721 tacaaggcat atgtttgtat gtactgtaag tagttattca tttttgtcag gtgatatcaa 6781 cgaatttttc gatatgttct tcaggcagag cttaccctct gccccaagcc ccccacgacc 6841 ctgtgtctat atcgtttata attgagttaa gttttcaata ttatttcttc gtctcttgtc 6901 gtttttttgt tttgtgatat tcgcggtggt gagaaagttg gccgaataat tgttgttcgt 6961 tgtttatatt ttgtgttcat ctatattttt gtagtttgtt ttatttttta taaatataca 7021 ttgtattaaa catatattaa atatacatta atgaactagt atatacaact taactataca 7081 catatacaaa taaagatgaa ttgaaataat agctcttaag gtacggagtt tttggcagga 7141 agaaatccac aaaagtaaaa ctgaacggag gagaacaagt ttttgggcaa cgactctgac 7201 gaatgataat tgatagcgat gatacatata ctcctaaaat aaaacaaaag aacccaaaaa 7261 aaaaaaaaat gaaaattttt taaaaatatt taataaacaa atcattatta cctattatta 7321 ttatatttat tattataatg aaacaaattt agttattatt catgtaaaga acgaaccagg 7381 aaggcaaagc aaagcgataa caaatcttgc gaaatgcaaa aacaacaacg agcgaagaag 7441 aaagcgaaga gaagaataat gatgaaagtg aattagtagc tggcaagtga gaatgacgat 7501 gaagaatgaa attatattga taatgaaaat acaacattta aagttattta gcagtaaatg 7561 ggaaaagaat taaaaacaaa catgaaaaca acagacatca atgaaaaaca acaaaacaat 7621 gaaatacaat aaaacacaag aaataaatta c //