Dbfetch
LOCUS NM_001274114 7517 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster muscleblind (mbl), transcript variant O, mRNA. ACCESSION NM_001274114 VERSION NM_001274114.1 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 7517) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 7517) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 7517) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 7517) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 7517) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 7517) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 7517) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 7517) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 7517) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 7517) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 7517) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 7517) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 7517) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 7517) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 7517) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 7517) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 7517) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 7517) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 7517) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 7517) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 7517) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 7517) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 7517) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 24 (bases 1 to 7517) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..7517 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="2R" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..7517 /gene="mbl" /locus_tag="Dmel_CG33197" /gene_synonym="BG01127; CG10941; CG14477; CG33197; chaste; chst; cht; Dmel\CG33197; l(2)01038; l(2)k01212; l(2)k05507; mb1; Mbl; MBL; mbn; mm; n(2)k07110" /note="muscleblind" /map="54A3-54B5" /db_xref="FLYBASE:FBgn0265487" /db_xref="GeneID:36945" CDS 1160..2911 /gene="mbl" /locus_tag="Dmel_CG33197" /gene_synonym="BG01127; CG10941; CG14477; CG33197; chaste; chst; cht; Dmel\CG33197; l(2)01038; l(2)k01212; l(2)k05507; mb1; Mbl; MBL; mbn; mm; n(2)k07110" /note="CG33197 gene product from transcript CG33197-RO; CG33197-PO; mbl-PO; MUSCLEBLIND; chaste; mindmelt; BG01127" /codon_start=1 /product="muscleblind, isoform O" /protein_id="NP_001261043.1" /db_xref="FLYBASE:FBpp0301760" /db_xref="GeneID:36945" /db_xref="FLYBASE:FBgn0265487" /translation="MANVVNMNSLLNGKDSRWLQLEVCREFQRNKCSRQDTECKFAHP PANVEVQNGKVTACYDSIKGRCNRDKPPCKYFHPPQHLKDQLLINGRNHLALKNALMQ QMGIAPGQPVISGQVPAVATNPYLTGIPANSYSPYYTTGHLVPALLGPDPVTSQLGPV VPQTVQVAQQKIPRSDRLEQFSGMVPFKRPAAEKSGIPVYQPGATAYQQLMQPYVPVS SSPKIPLNASCVIYTDASGQLLDTLPVCQDFNRSMCSRLNCRFVHLTEDDKVEVIDQR VAVCRDHANSQCRRKQCKYYHIPIVLPPANIMAAMITSPSDQQPAVPVATTTANPAAA AAAAAAATAAGYNGTSNLIIIEPQQQQQQPPQQQQQFSYHSNSSNNNYYHSNASKQAA HASNMYQQQQQQHQQQQQHQQHLQHQQHAQQQTHITYHCSSPYSPSSASSSSSCSIAT SPTLSSATTLSTTSTATMPTPQQQYQGPAATATFLKAPAYYTDATPTLVLSSDYNSNC IPIQATPFISLQAAPQQHLLKYTTQAPPPQAQQHAFVGHHYQTQMGQVVATTVAAIPA TTITVAPATVASPSTCI" ORIGIN 1 tcagtttcga aaaatttttc gatggaagcg gttctgtcag cggaaaagtg aattatacca 61 gagcctgcct gaaaaactca agaaaacccc atcaaagaaa tagcagctct cagctaaata 121 ataacaaaca caatactttc tgctcagtca ccgcaaacag aaataatcac aattctgcaa 181 aacgccgtca tcaaaaaagt tttagcctac aactctagaa acgcggaaaa atttgtcaaa 241 aatacaacta aaaaaacaac aacgcgagtg cacgtgtatg tgaggtgctc agtaagagtg 301 tttgcgtgtg ttcgtttctg tgtgtgacag ataataaaag gagaaaaaaa gaagttgtcg 361 aaagtcgttc gtgaaaattc aagaaaaata gtgcaagcgc tgcagggaaa ttgtccggaa 421 aaatcgcaaa atccattgtt tttagccggc atcttaaaaa ccaacgataa caacagcttc 481 tgcaacaacg cgcgtgttta gttcacacac acaccacgga gcgtcgagaa aaaaaggtta 541 aaaatacatt ttcaattcac catcggcgta aaagtaaaac aataaacaaa tacaagaaaa 601 taaaacagca gccgcttttt cacccaacaa caacaatttc aacaacttca acttcgccag 661 cagcaacaac aacaagtcag ctggacaacc gaagataatg taaactcagc ttacacacaa 721 aaaagcagta aaatataaaa tacaaaaatt aacagctgcg tttatctata gatatatata 781 tacacatcta tatatttgaa taagcgttcg atttgaatca aaattatagc ccaagctatc 841 agctaccccc acaagctttg tactccacaa aaacgctaac gagcaaaatc gataaagacc 901 agatagcaaa tgaaatcata ccatctgcca tagatctatg ctataaacat atataggtgc 961 tgatctgtgc tcttgaattt agtgtttttt gtgtgtgcgt gtcgcgagag gagcactcaa 1021 aaccaaaaaa aaaaaaaaaa acgtatagta aaacaaaaaa ctatctctag tcgctaggct 1081 ataactatac aaactccagc tatcccagat ccagatccgt aaacagcaaa tagttatata 1141 tctataaccc caaaatacga tggccaacgt tgtcaatatg aacagcctgc tcaacggcaa 1201 ggattcgcgc tggctgcaat tggaggtctg tcgcgagttc cagcgcaaca aatgctcgcg 1261 ccaggacacc gaatgcaagt tcgcccatcc cccggccaac gtggaggtcc agaacggcaa 1321 ggtcaccgcc tgctacgaca gcatcaaggg ccgctgtaat cgtgataaac cgccgtgcaa 1381 atactttcat ccaccacagc atctgaagga tcagttattg ataaatggac gcaatcattt 1441 ggccctcaag aatgcactga tgcaacagat gggcatcgcg cccggccaac cggtcatatc 1501 gggccaagtg ccagccgtgg caacaaaccc ctatctgacc ggcattccgg ccaactcgta 1561 cagtccgtac tacacaacgg gacacctggt gcccgccttg ctgggtccgg atcccgtgac 1621 ctcccaactg ggacccgtgg tgccccaaac agtgcaggtg gcacagcaga aaataccacg 1681 ttccgacaga ttagagcaat tctctggcat ggtaccgttc aaacgtccag ctgccgaaaa 1741 gtctggcatt ccagtttatc agcccggtgc gaccgcctat cagcagctaa tgcagcccta 1801 cgtgccagtc tcatcgagtc cgaaaatacc cttgaacgct tcctgtgtca tctacacgga 1861 tgccagtggc cagttactgg acaccctccc ggtgtgccaa gattttaata gatctatgtg 1921 cagtcggtta aattgtagat tcgttcattt aactgaagat gacaaggtcg aggtgattga 1981 tcaacgtgtt gctgtctgcc gcgatcatgc caacagccag tgccgccgca agcagtgtaa 2041 atactaccac ataccgattg tcctgccgcc ggccaacatc atggcggcca tgatcaccag 2101 tcccagtgat cagcagccag ctgtgccggt ggccacaaca acagccaatc cggcggcagc 2161 ggcggcggcg gcagcagcag caacagcagc cggctacaac ggcaccagca acttgataat 2221 catcgagccg cagcagcaac agcaacagcc gccgcagcag cagcaacagt tcagctatca 2281 cagcaacagc agcaataaca actactacca cagcaatgcc agcaagcagg cagcacacgc 2341 cagcaacatg tatcaacagc agcagcagca gcatcagcaa cagcagcaac atcagcaaca 2401 tctgcagcat cagcaacacg cgcagcagca aacacacatc acctaccact gcagctcgcc 2461 ctactccccc tcgtcggcat cctcttcatc ctcctgctcg atagccacct cgccgaccct 2521 ctcgtcggcc accacgctat ccaccacctc gacggccact atgcccacgc cccagcaaca 2581 gtatcagggc ccggcggcca cggcgacctt tctaaaggcc cccgcctatt ataccgatgc 2641 cacgcccacc ctggtgctga gcagcgacta taactccaac tgcatcccca tccaggcgac 2701 gccgttcatc tcgctgcagg ctgctccgca gcaacatctg ctgaagtaca ccacccaggc 2761 accgccaccg caggcgcagc agcatgcctt tgtgggtcac cactaccaga cgcagatggg 2821 ccaggtggtg gccactactg tggcggccat tccggccacc acgataacgg tggcgccggc 2881 aacagtggcg tctccatcga catgcatcta gaagaagggg gtttcttatc tgccgcaggg 2941 ggcagctctg tttattttac cagagacgta tattaggtca tagggatgtg tttcctgcga 3001 agtccctata gatttgaaaa cattagttat ggcgcccaaa agtgaaaagt gaaatattta 3061 aaactaaaga gttatttgag cacttttaat taacataatt ttgaaatatt atcctgttag 3121 ccataggagg aactaaaatg ttcattttat aaagtctagc atacttttaa gcaccttaat 3181 tgatgttttc aaaaaccaag aggcccaaga aacacatcgt atagggtttt tctttattaa 3241 aagtttgtca cctaccttta tccattgaat actcgttttt gtcaactcca gttcacctag 3301 atacttatat tgcataatcc tcaaaaccta agcaacacaa tacgtatacc aatcatgaat 3361 actccccaag cgatgctcta cacgagactc caagctaaat tgaaagaaat caaaaagcaa 3421 atgcagaact tgtctgaaaa aggtctaagc tagtaaataa aacttcaaac aatcacattc 3481 tacgaaacac aaacacaaag cagtaatgga agtttttgat gaaaattaaa ggttgatacg 3541 aactatttac aaaaaataag aaccgaaagt acttttgggg gaaaggagaa aggtaaactc 3601 aactgaactt tttcgtacgt atagcaagac tttaacgtgt aagcatctca tttacacatc 3661 aagtgacatg cattagaggg aaaacattga gtgaagactc tacaatattg caaaacccaa 3721 acagaagaga tgaataatac gagtgttgtt aaatgcgaaa agaaactaaa gaaaattagc 3781 aattaaaaat tgaaattaat attacaagag aaagaacttt ggaggagagc gcagttgcat 3841 taaaattagt tacaaactat tttaaactct agtgttccat atttcaatgc aaataaaaaa 3901 tacaaataaa agtgaataaa gataaaggta cattaaagtg gataaacata tagtgaggag 3961 tgttaatatt agctaaggtt aagcctgaca aaccgttctc catggcaaat agtcaaaatt 4021 aatcaaaaac agaatctaca taggccatag ataagcagca agaacaacta ataataaaca 4081 cttaacaata acaataataa taacgataat gataacgata acgaaaacga tgaggatgaa 4141 gatgaaaaaa gtacagtcac gtcctatttt tgcaacaacg atttactaca agcgagaggc 4201 aaacgatacg gagattttat taagcaaaat ggtcagcaga ggtcagataa agaaaacaga 4261 gtacagaaac cataatcctt ttttacattt tataataacg atcaagataa atcagcagaa 4321 ctacagcaag agaaaccata ttttttatat acaatggaag catcaaaaac aacactgata 4381 aacaaaatcg atatgaggta aacaaacaag aaatttaatc aaatttaaag gaataagcat 4441 tttttgcaaa caacaaacaa agacggagac ttttttaaag tgtattaata acaacttatt 4501 tagctgaatt ctctagcaaa tgaacacaaa gaactctaaa caacatttaa tgaggataac 4561 cactcagctc acacagaaat cgaaattgta ccgtattata tcttcctatg caaacgattt 4621 gtaagcacta tatatgtata tagaaacata cccactatat gcgacattta cgaatccaga 4681 cttatttccg attaactgtt cgtttacagt ttgccgctgt tttaatgacg ttttgtgact 4741 tgttttttat acactcaaga acgtatttgg aacacacata ataagaatta cattaaattg 4801 cagaacggaa actacttatt atatacaaaa gcatacgtac atatatacac catatatgta 4861 tatatactac atatatttat gtctgtacac gtatgaatat atatacatta acacaaatat 4921 attgattata tatatacata tatatattta ctaatggcaa ctaaacatga aatgtgatct 4981 tttaaagaaa caaaaagtaa agaaagaaaa ataataatta aacgatggca ggcagaattg 5041 gataaaggta aaactgaatt aaagtaaatc gaactagcag caatcgaata ctagagccat 5101 ggcaagcagg atagttaaac gtaattttaa atgggttcca tctcgaggca agcgtacgaa 5161 tatctccatt caataaggat aacaccaata atactcgaca tctagctaat aattgttcag 5221 caataacaga tatatctaca tatacattta agggctggct ataatatacg gaaatttgtt 5281 ttttttttca tcgcaatcac actatcacct atcactatca cctattacta tctctcaatc 5341 tcactactgt ccgtacacct gagttcctcc ttttcaataa gactcggata gcgtatatcc 5401 agcacctaaa cctaaccact tgtagtactc aacttcagct cgctctcttc gaagcctcct 5461 ccaaacttac tcgatcacac ggaagtcgta tcccgaactt ttccgtactc aaaataagaa 5521 tgcctaataa gtttccgtcc attataatca gaccttaaat ctatgtgcaa cgacagcgga 5581 agcagaagca agtggaacag ttgtaaacga ataaaagtaa attaactaaa gtaaacaatt 5641 aaagtaaatg attaattata aacacaatac acgtagattc tcaaactaaa agctcgtcga 5701 cattttaaca gttactaaca tttaaataat aataacgaca aatgagtaat acaataagct 5761 gcaaaagggc aaacaaaaaa agggaaacca tgatgttttg tgtaaaaata aatgttcttt 5821 aaagagaaaa aatttaaaaa tcgaaaaaaa acacacacac aaaaaccaat aaacgaaaat 5881 gagaaatcct agttactaag caaactaact acgaacatat agacactata gaatcattgt 5941 accataagag atttcagcgg gattttgttc aacttgacat cttctctagt atgtgtagat 6001 tggcatgtca tttgacatgg ccacgcatgt agaatagcac gagtttgtaa actagaaacg 6061 aaacttttat ttgccttaac atcaaaccaa tatatacacc aatatacatt gatttaaatc 6121 ttctgaatag tttcgaattg tttcgaaaac caatttcact tgacgcatgt acatggcgct 6181 cttaaaacaa acagatacag atactatatg acagcagaaa ataattctga atcgaaggga 6241 aaacggatta atgtagttat gtgtagagtc tccttcattg taagtcatag ttattattgt 6301 taattttaat ttatatttac acatatatat tagatcatta tgattattaa ttgtgaatat 6361 gatgtgatgt gtttattgaa agaaaaacaa aaacgaaact aaaacaaaac aaaacaaaat 6421 cgaaaataca attactgaat gttgcaacgt aaagaaaact aaatgtattg aaccctgagc 6481 gaagagtgaa gcgaaattac aagaaacctt atcgagaatg tgagggaaaa tcaattttac 6541 tccacttcgg atggttaagt aagcgtaatg ttaaattaca ctatgataca aggcatatgt 6601 ttgtatgtac tgtaagtagt tattcatttt tgtcaggtga tatcaacgaa tttttcgata 6661 tgttcttcag gcagagctta ccctctgccc caagcccccc acgaccctgt gtctatatcg 6721 tttataattg agttaagttt tcaatattat ttcttcgtct cttgtcgttt ttttgttttg 6781 tgatattcgc ggtggtgaga aagttggccg aataattgtt gttcgttgtt tatattttgt 6841 gttcatctat atttttgtag tttgttttat tttttataaa tatacattgt attaaacata 6901 tattaaatat acattaatga actagtatat acaacttaac tatacacata tacaaataaa 6961 gatgaattga aataatagct cttaaggtac ggagtttttg gcaggaagaa atccacaaaa 7021 gtaaaactga acggaggaga acaagttttt gggcaacgac tctgacgaat gataattgat 7081 agcgatgata catatactcc taaaataaaa caaaagaacc caaaaaaaaa aaaaatgaaa 7141 attttttaaa aatatttaat aaacaaatca ttattaccta ttattattat atttattatt 7201 ataatgaaac aaatttagtt attattcatg taaagaacga accaggaagg caaagcaaag 7261 cgataacaaa tcttgcgaaa tgcaaaaaca acaacgagcg aagaagaaag cgaagagaag 7321 aataatgatg aaagtgaatt agtagctggc aagtgagaat gacgatgaag aatgaaatta 7381 tattgataat gaaaatacaa catttaaagt tatttagcag taaatgggaa aagaattaaa 7441 aacaaacatg aaaacaacag acatcaatga aaaacaacaa aacaatgaaa tacaataaaa 7501 cacaagaaat aaattac //