Dbfetch
LOCUS NM_001272389 9308 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster Ubr3 ubiquitin ligase (Ubr3), transcript variant C, mRNA. ACCESSION NM_001272389 VERSION NM_001272389.1 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 9308) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 9308) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 9308) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 9308) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 9308) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 9308) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 9308) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 9308) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 9308) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 9308) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 9308) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 9308) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 9308) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 9308) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 9308) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 9308) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 9308) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 9308) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 9308) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 9308) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 9308) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 9308) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 9308) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..9308 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..9308 /gene="Ubr3" /locus_tag="Dmel_CG42593" /old_locus_tag="Dmel_CG1530" /old_locus_tag="Dmel_CG1531" /gene_synonym="CG1530; CG1531; CG42593; Dmel\CG42593; ubr3; UBR3" /note="Ubr3 ubiquitin ligase" /map="7C8-7D1" /db_xref="FLYBASE:FBgn0260970" /db_xref="GeneID:31713" CDS 1014..7670 /gene="Ubr3" /locus_tag="Dmel_CG42593" /old_locus_tag="Dmel_CG1530" /old_locus_tag="Dmel_CG1531" /gene_synonym="CG1530; CG1531; CG42593; Dmel\CG42593; ubr3; UBR3" /note="CG42593 gene product from transcript CG42593-RC; CG42593-PC; Ubr3-PC" /codon_start=1 /product="Ubr3 ubiquitin ligase, isoform C" /protein_id="NP_001259318.1" /db_xref="FLYBASE:FBpp0303731" /db_xref="GeneID:31713" /db_xref="FLYBASE:FBgn0260970" /translation="MDEDDNLSNADISIDDEEVVREQTHHPPMQEDQELDNEDGSSDV DLSSVYVVPPIVSAPSPASVRIAGGSTIGGGGVAAGAVPTTTDNSHSPFHDWDSSVAA AAAPPPPPPRTGPTTTTSSGTAAESGAASALSDDAGAKPSFFFGASSFSLRSRKEVAA LINTECCRGSPTPDLDSIMDTLFNPGTPIDNLDNIEWIRWLIAGGRTPQEFVKIVRSY DNHAKCGLVWVPHVVAYRCRTCGISPCMSICRDCFKKGNHTNHDFNMFLSQAGGACDC GDTSVMKAEGFCSDHGINNRVNRDPVPNNLLAVAEAIMPKLLFRLLQHFREHSDTPLE VQAITSYSCEEFANMLIDLNNMGEIMRKVMTRTLINPEVYAFFMEAPCQDTRNGRFLK ANREKYEDAVNRFPNPEPPDEYRDLPALGDKLVHTTLLEEFIFWTFKFEFPQTLVCFL LNMLPDQDYKEHLTRTFVMHYSRIPSVLEMSRDPDTLSNRVVHMSVQLFSNESLALKM VNELSLLHVMIISLKLMMSKILIQNTLHDPNKNFHFVIDCTRQVMKDHCYWPLVSDFN NVLSHESVALVFLRDDNLIDMWFQFLQMLQGMNVNVRETASHVEFEPNSYYAAFSCEL EASAYPMWSIISHLQDGTHAHLAKKIINYCVTTLHEWLDSIYFMEARLSMEEMMQASF HFPLHRYLAAFVCQAVTKMGISLNDVLPSRPYLLPLLMIHPLRVQSFFYEILAGKWVR NGLQIKGQAMTYIQANFCNSMADMDLFFLQICATNLPQYFFLQNTIELFDVGQWLETA PLKQPQKAEQSSMLEGFLTFLATLVTSRTNLGNDEATQCIIEISALLATENKTHSQLL ELMPERSGNVHTKNFETFLKKLSVYKAPSSGSENLEQGLFTPIDEVWEKHYDPLHVLL RAVHRRDFQSSLDRFTNYVKSKDKMPASGNLWPPFRLPHALPATSSFSDPCKILNSRI FHSTILSIFFRAVHTRDVSEHLLALAVFLLEIAVETSDDVGSGTGDRAPPALAAVVES SSGPGYHGYGTGRHEPPKLFHCYPTDNLSCNLRHVVKKVSLKSRDPQVITSSYRSNPF YSDLDFEVEADPEQSMRMIGQGDPEGDEATGGAGLGMGAHSRRNVSQALVPMRVPGME VALPPDLSVVAETGVVIRQDSNEDDLLREGNHAMDMSPPAALDFHFPLQQITLPESGM EVAIRRDLLLAETNNMGAIAGGAGGGANASATPPAGASNEMFSPTTPTGSGMLLPFQR VQPVAVPSSGNMDIVPSNAMGAGGSFTSGVSGSGTGRRMNYETGGARKRSVDIAIGGS NKDELHLDESILSLLLKLHSQLSGTLDSFSLSDGEDQSSDDDSTMDVDCNEASTSMAA AESTALAERGRSKRNYKNIHVSSSRIGDGPFFIGNLLRKIAKQDEQCAQSIDDIRARL WPNQREKQAEAKAREAKEKEERRKKARERQQKMMQDFANKQKLFMQSAAASSSGMGYG PEDEDDEELYEEQPREKEYDCIICNCTTPSTESNPIGLVVLVESSGIVGHRRRIAERL PLPINAEDESRLAHTTRLAAEFNRRTELLSLKFGDESWYLSNNMAYDNGVHVQSCGHH VHLSCLEAYLKTLYTTQRQPVQDRGEFYCPVCRQLSNSVLPLSPQLDRPTHLVRSGNQ PFERLVADLTDLIKENETIPPTKLTEAMGHAMEVMTNIAQRKVKCSSITFRKLFIFVT SIARTNLEAEIIQRGGSLCTANATRYKPKRECIVPLLHVLSVHVRVLVEWPLWSSWAS LAGLPVTATEPLPAHCLELIPSILADPIALLLKFILLAPLQLDQDYFTCMVKVMYNLL YYQIVVQLCVTLTDLECDHIVKVYGSTSVGSDNSAAESQQQESAAGTTNNRRRAGQQQ QSSSQLGKAMALVLSQTNDLVHLRRDCIPSTSSSAAASAAGSSSTTSTNHGASAATAS SATTIEVNLKSMELQLQALCLPFLRVAALLRQHLYRHEMPEISAPGLEFVRLVYYLEL VTDSMDWDCFNASKGLCFIPGTETTLPQFWCQQLMEVRPPADTVRELVLINQHSLWQQ PRLLELPREYERLFTYYHERPCLNCYKVPKESSICLLCGTIVCLKQNCCAENDCCEAV RHTLSCGGGIGIFLVVTSTYIIVIRGRRACLWGSLYLDDFDEEDRDLKRGKPLYLSKD RFNLLESQWLSHKFAHTKHTWVFHRDLL" ORIGIN 1 caggtgtaga gcggtcacac tggatgaaat tcaagaccta tcgatatcct gatatacacg 61 ccaacgaaga ccgtgtgtgg attcgtggag caaatcgaag ttggcaggat taaaggcatt 121 cgcgaacgca gaggcagcag ctaaagggcc acccatgcac caaagaaaca aactagctgg 181 cccagcggtt catttatctg cgactaacaa gctaaaatcg gcgtaattgg caagttcaat 241 gcacgactaa tatatttggc cacacttgcc agtgtatgtt tgttcgtgtg cgtgcctgtt 301 tgtgtggtgt cgtctccgta cgtgtttgtg tgtgtgtccg cgacgagtat gtgtgcgcac 361 atattcgtat atctgcaaga ctcgcggatg aaacagcgtg aaaagtgagc aaaatatcgg 421 ggaaaaacgg cacggtacgg ccacagaacg gaacggtacg gtgcgatacg atatcgagaa 481 aaggccatca gccagagtac tcctcgatcc ggaaacggat aatggggata tagatgatac 541 agccaatagc tccccgaaag ccacagcaca caataggtcg gtcggtcggt cggttggttg 601 ggcgacgtcg ccgagagtta aacatcaaaa atcaaaccca ggaaccgacg gagctaagtg 661 tcaagtgttt ggtgttgtga aatttttcgt ttccagctct ccgttcagcg ttcagccaat 721 ttgccaacct tttcccctct ttaatttgtt atccccggac accacaagag tttcgatcaa 781 aattttcaat tgaacgcaac atcgccataa acaaaaacat aaagtaacgt agaagaagca 841 gcagccgaag ccgaaaaaag acgaaaagaa aacttgtttg aaaaggccga accgaaagaa 901 gaaaaagagc agcagcagca gcacagcggc caagtttgga agaatttcag aatttcagcg 961 tgctaggaac ggagcagcgg accggcgacg tcaccaaata aacgcccatc accatggacg 1021 aggatgacaa cctgtccaat gccgacataa gcatagatga cgaggaggtg gtgcgggagc 1081 agacccacca tccgcccatg caagaggatc aggagctgga taacgaagat gggtcatccg 1141 acgtggatct gtcttcggtg tacgtcgtgc cacccatagt ctcggcacca tcgcccgcat 1201 cagtgcgcat cgctggtgga tccacaattg gtggcggagg ggtcgcagct ggagcagttc 1261 caacaaccac cgataactcg cattccccct tccacgattg ggattccagt gtggcggccg 1321 ctgctgctcc accgccgcca ccgcccagga caggaccaac tacaactaca agctccggca 1381 cagccgcgga atcgggagcc gcgtccgcct tatccgacga tgccggcgcc aagccaagtt 1441 tcttctttgg cgcctcctcg ttcagtttgc gcagccgcaa ggaggtggcc gccctgatca 1501 acacggaatg ctgccgtggc agccccacac ccgatctcga ctccataatg gataccctat 1561 tcaatccggg gacgcccatc gacaatctgg acaacatcga gtggatacga tggctcattg 1621 ccggcggacg gacgccgcag gagtttgtta aaattgtgcg cagctatgac aaccacgcca 1681 aatgcggtct ggtatgggta ccgcatgtgg tggcctacag gtgccgcact tgcggcatat 1741 cgccctgcat gtccatatgc cgggactgct tcaagaaggg caaccacacg aaccacgact 1801 tcaatatgtt cctgtcacag gcgggcggtg cctgcgattg tggtgacacc tcggtcatga 1861 aggcggaggg tttttgcagt gatcatggca tcaataatcg ggtgaatcgc gatccggtgc 1921 caaacaatct tttggcagtg gccgaggcca taatgcccaa gctgctcttc cgcctgctgc 1981 agcacttccg tgagcacagc gacaccccac tggaggtgca agcgataacg tcgtactcct 2041 gcgaggagtt cgccaacatg ctgatcgatc tgaacaacat gggcgaaata atgcgcaaag 2101 tgatgacgcg cacgctgata aatccggagg tgtatgcctt cttcatggaa gcaccgtgcc 2161 aggacacccg gaatggacgc ttcttgaagg cgaaccgaga gaagtacgag gatgccgtca 2221 atagattccc aaacccagag ccacccgatg agtacagaga tctgcccgcg ctgggcgaca 2281 aattggtcca caccacgcta ctcgaagagt tcatcttctg gacatttaag ttcgagtttc 2341 cacagactct ggtctgcttt ctgctgaaca tgctgcctga tcaggattac aaggaacacc 2401 tcacccgcac atttgtgatg cactacagcc gcataccgtc cgtgttggaa atgtcccgtg 2461 atccggacac gctcagcaac cgggtggtcc acatgagcgt ccaactcttc tctaacgaaa 2521 gtctggccct caagatggtc aacgagctgt cgctgctgca cgtaatgatt attagtctga 2581 agctaatgat gtccaagata ctcatacaga atacattgca tgatcccaac aagaattttc 2641 atttcgtcat cgactgcacg cgtcaggtga tgaaggacca ctgctactgg ccactagtct 2701 cggactttaa caacgtcctt tcacacgaat cggtggccct ggtctttctg cgggacgaca 2761 atctcatcga tatgtggttc cagtttctcc agatgctcca gggcatgaat gtcaatgtgc 2821 gcgagacggc ttctcatgtg gaattcgagc caaatagcta ctatgcggcg ttctcctgtg 2881 agcttgaggc cagtgcctat cccatgtggt cgattatctc gcatctgcag gatggcacac 2941 atgcccatct ggcaaagaag atcatcaact actgtgtgac gacgctgcac gagtggctag 3001 actctattta ctttatggag gcgcgtctat ctatggagga gatgatgcag gcttcgttcc 3061 actttcccct gcatcgttat ctggctgcct ttgtttgcca ggcggtaact aaaatgggaa 3121 tcagtctgaa cgatgtgctg ccctcacgcc cctatctgct gcccctgctg atgatccatc 3181 cacttcgcgt ccagagtttt ttctacgaga tcctggccgg aaaatgggtg cgcaatggtc 3241 tccaaatcaa gggacaagcg atgacctata tccaggcgaa cttctgcaac tcgatggccg 3301 acatggacct gttcttcctg caaatctgtg ccaccaacct gccgcagtac ttctttctgc 3361 agaacaccat cgagttgttc gacgtaggtc aatggctgga gacagctccc ttgaagcagc 3421 ctcaaaaggc ggagcaatcc tcgatgctgg agggattcct aaccttcttg gccaccctgg 3481 tgacgagtcg cactaatctg ggaaacgatg aagccaccca atgcattatt gagatcagtg 3541 ccttgttggc taccgagaac aagacgcatt cgcagctcct tgaactaatg ccggagcggt 3601 cgggcaatgt gcataccaaa aactttgaga ccttccttaa gaagctatcg gtttacaagg 3661 ctccgtcgag tgggagcgag aacctggagc agggtctctt cacgcccatc gacgaggtgt 3721 gggagaagca ctacgatccg ctgcacgtcc ttttgcgagc agttcatcgt cgagactttc 3781 aatcatcgct ggaccgcttt acaaactatg tgaagagcaa ggataagatg ccggcaagtg 3841 gtaacctatg gccacccttc cgattgcctc atgctctgcc cgcaacgagc tccttcagtg 3901 atccctgcaa gattttgaac tcgcgcatct ttcactccac catcctgtcg atatttttcc 3961 gtgcagttca cacacgtgat gtttccgagc atctgctggc tctggctgtg ttcctcttag 4021 agattgctgt ggaaacaagt gatgatgttg gcagtggaac tggagatcgg gcccctcctg 4081 cgctggctgc tgtggtggag tcatctagcg ggccgggcta tcatggctac ggcacgggac 4141 ggcatgagcc gcccaagctt ttccactgct atcccacgga caatctaagc tgcaatctgc 4201 gccacgtggt caagaaagtg tcgctgaagt cacgcgatcc gcaagtgatc acctccagct 4261 atcggtcgaa cccattttac tcagatctgg actttgaggt tgaagcggat ccagagcaat 4321 cgatgcgcat gattggtcaa ggggaccccg aaggagatga ggcaacgggt ggagctggac 4381 tgggaatggg agctcatagc agaaggaatg tctctcaggc gctggtgccg atgagagtgc 4441 ccggcatgga ggtcgcccta ccaccggatc tttcagtagt tgccgaaacc ggtgtggtta 4501 tccgccagga tagcaacgaa gatgatctac tgagagaagg caatcatgcc atggatatga 4561 gtccaccggc tgctctcgat ttccactttc cgctgcagca gatcactttg ccggagagcg 4621 gaatggaggt ggctattcgg agagatcttc tgctagccga aacgaataat atgggcgcaa 4681 ttgcaggtgg agctggaggt ggcgccaatg catcggccac accaccagca ggggcttcca 4741 atgagatgtt ctcgcctacc acacccacag gcagcggtat gctcctgcct ttccagcggg 4801 ttcagcctgt agccgtaccc agtagcggta atatggatat tgtaccatca aatgccatgg 4861 gtgccggcgg aagtttcaca tccggcgtaa gtggtagcgg cactggacgt agaatgaact 4921 acgaaacggg tggagcacgt aagcgatccg tggacattgc catcggtggc agcaataagg 4981 atgagctgca tttggacgaa agcattttgt ccctgctact aaagcttcat tctcagctct 5041 caggcacact agatagcttc tcgttgagcg acggtgaaga tcaatcatct gacgacgatt 5101 cgaccatgga tgtggactgt aacgaagcca gcacctccat ggcagcagcg gagagcactg 5161 ccctggctga gagaggacgc agtaagcgca actacaagaa cattcatgta tcctcctcgc 5221 gcatcggtga cggaccattc tttattggta atctgctgcg aaagatcgcc aagcaggatg 5281 agcagtgcgc ccagagcatc gacgacatcc gtgccagact ctggccgaat cagcgtgaaa 5341 aacaagcaga ggcgaaagca cgcgaggcca aggagaagga ggagcgccgc aaaaaagcac 5401 gtgagcgcca gcagaagatg atgcaagact tcgccaacaa gcagaagctc ttcatgcaat 5461 ccgctgcagc gtcatccagt ggcatgggct acggaccgga ggacgaggac gatgaggagt 5521 tgtacgagga gcagccgcgt gagaaagagt acgattgcat aatctgcaat tgcactacgc 5581 ccagtaccga atcgaatcct atcggcttgg tcgttctggt cgagtccagc ggcattgttg 5641 gtcatcggcg gcgcatcgcc gagcgattgc cgctgccgat aaacgcggag gatgagtccc 5701 gactggcgca caccactcga ctggcggctg aattcaacag gcgcacggaa ctgctcagtc 5761 tgaagtttgg cgatgagtcc tggtatctgt ccaataatat ggcctacgac aacggtgtac 5821 atgtgcagtc gtgtggccac cacgttcatc tcagttgcct agaggcatac cttaagacgc 5881 tgtacaccac ccaacgtcag ccagttcagg atcgtggcga gttctactgt cccgtgtgcc 5941 gacagctctc aaactcggtg ctgccgctga gtccacaact ggacagaccc acgcacctgg 6001 tccgctctgg taatcagcca ttcgaacgtc tggtcgccga tctaacagat ctgattaaag 6061 agaacgaaac gataccgcca acaaaactga cagaggccat gggccatgcc atggaggtga 6121 tgacaaacat tgcccagcgc aaggttaaat gctcctcgat aacgttccgc aagctgttca 6181 ttttcgttac ctcgattgcg cgtacaaacc tggaggcgga gatcatccag cggggcggat 6241 cactatgtac agcgaatgcc acgcggtaca agccaaagcg ggaatgcatc gtaccgctac 6301 tgcacgtgct atcggtacat gtgcgtgtct tggttgaatg gccgctgtgg agcagctggg 6361 cctcgttagc tggcctgccc gttaccgcta cggaaccgtt gccggcgcac tgcctcgaat 6421 tgattcccag catattagcg gatcccattg ctctgctgct caagtttatc ctgctggcgc 6481 cactgcaact cgatcaggat tactttacgt gcatggtgaa agtcatgtac aatctgctgt 6541 actatcaaat tgtggttcag ctgtgcgtta ctctcaccga tttagagtgc gatcacattg 6601 tcaaagttta cggcagcact agcgttggca gtgacaactc tgctgcggaa tcccaacagc 6661 aggagtctgc cgccgggaca acgaacaacc gtcgccgtgc tggacaacag cagcagagct 6721 cctcgcagct aggaaaggcc atggccctgg tgctgagcca gacaaatgac ctagttcact 6781 tgcgacgcga ctgcataccc agtaccagca gctcggcggc agcgtcggcg gctggttcct 6841 cctccacaac gtccacaaac catggagcta gcgcagccac agcctcctct gccacgacga 6901 tcgaggttaa tctgaagtcc atggaattac agctgcaggc gctatgcttg ccgtttttgc 6961 gagtagctgc cctgctgcgc cagcatctct atcgccatga gatgccggag atctcggcac 7021 cgggactgga atttgtgcgc cttgtttact atttggaact cgtaacagat tctatggact 7081 gggattgctt taatgccagc aaggggctat gctttattcc cggcactgag acaacgctgc 7141 cccagttctg gtgccagcag ttgatggagg tgcgtccgcc ggccgatacg gtcagagaat 7201 tggtgctcat caatcagcat tcgttgtggc agcagccgcg acttcttgaa ttgccgcgcg 7261 agtacgaacg cttgttcacg tactaccatg agcggccgtg cctcaattgc tataaagtgc 7321 ccaaggagag ctccatctgc ctgctgtgcg ggacgatcgt atgcctcaag cagaactgct 7381 gcgcggagaa tgactgctgc gaggctgttc gccatacgct atcctgtggc ggtggcatag 7441 gcatcttttt ggtggtcacc tccacgtaca tcattgttat ccgcggacga cgcgcctgcc 7501 tttggggctc actctatctg gacgacttcg atgaggagga tcgcgatctc aagcgcggca 7561 aacctttgta tttgagcaaa gaccgcttca atctcctgga gtcgcagtgg ctgtcccata 7621 agtttgctca tacaaaacac acatgggtgt ttcaccggga tctcttgtga aatatggaag 7681 atctactgcg cagcatccag gagctggttg gccagatctg agatgcccta tccacgccta 7741 gtcgaaccag tcaaccacaa aaccacccaa ccacacaacc acacgatcac ccgtccccaa 7801 aatccgcctt cagcagctga atcaccacta atccaatcaa ccacctgact aaaagctagt 7861 ttccacattt tgtcggcttt tcgtatccgt ttacgcatct gcattttgtt tacggctttc 7921 gatccccatc ccccaccaca tgccccaaac gcacctagaa gcaatgtagg caatttgcaa 7981 ttaattgata ttaaacattt ttttttaata cataaacaat acttataaat atggatgcaa 8041 agggatacga aataccgaca actatactat tgtttgttgt caacttttta agtgagaaac 8101 gcataataca ccttatacag aagatcacat aatcttgcga tcgacaacaa tatttaacaa 8161 ccaattataa attacaaata ttattaccca cccacttgct gggcaaagac gacgcgaaaa 8221 cagcctggat aaaacggaga tggtgcatcg cgcgggtctt cagttgcgtt ctacctaaac 8281 taagtcttaa gtccttaact ttatagattt ttttttttag ggaaagaaag gcaagaaggc 8341 aaataacaaa ttacgagtaa caaataacac gatactacac aatataaaat tgcctacatt 8401 ggactcatga gtttgtgcat gtaaaaaatg aaaaaaagat tatatagtta atatatacaa 8461 atacaatata cactacagtt aattgcaaca taaacgaaaa atgatacaaa aaaaaaaaaa 8521 aaaacaataa acgaaaagcg aattgtgaaa tgcatagaaa ctagtttgca tgccccatta 8581 tacataaata ttatgtaatt aagaagcata agaaaaaaga tgattgaaag aacgagaagg 8641 gtaatcaatc tgaattggaa acgctaggat catcggatgt gaatttgtta ttagttttta 8701 caaattgtgt gttatttagg cggcgcttca agggaacttc gatattgttt gagcgcatat 8761 gtttattttg aacgatcaaa ttgagccact gcaaagacta gctaatattt caatatctag 8821 aagtatatac atacatatat ataataggtt tttcaagcaa attcaaaatt gttgaagata 8881 gtatcttcgg caaaaaaaaa cctggttgtc tagtaattgg tataaatttc catcaagtta 8941 tagaaaaatt gcatgtgcgt tacacgaaaa gacatggaag aattgctacg aattgtaaat 9001 acactgaaaa cgaagctgca tcttgtataa ttaaatatta atatatcaca gttttatctt 9061 tttttttttt ttactagtta tacaaatcta gatgttttgg ttggcctcct agactaacta 9121 aattcaattc tgcaaaacaa acaaacaaga aaaacacatg atttaagaga ttaaatggca 9181 cagcacagca atacacaata cacactcaat acacacaata cacacacagc ccctagtact 9241 ctagtacacc caaaaaagat aatgtaaacg tgcattctga gtgacaaacc gaaaaccctt 9301 aataaaat //