Dbfetch
LOCUS NM_001259856 5686 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster myosin binding subunit, transcript variant N (Mbs), mRNA. ACCESSION NM_001259856 VERSION NM_001259856.2 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 5686) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 5686) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 5686) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 5686) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 5686) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 5686) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 5686) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 5686) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 5686) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 5686) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 5686) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 5686) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 5686) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 5686) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 5686) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (10-NOV-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 5686) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 5686) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 5686) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 5686) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 5686) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 5686) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 22 (bases 1 to 5686) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 5686) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 24 (bases 1 to 5686) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 25 (bases 1 to 5686) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jan 16, 2013 this sequence version replaced NM_001259856.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..5686 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="3L" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..5686 /gene="Mbs" /locus_tag="Dmel_CG32156" /gene_synonym="0573/06; 0953/04; CG32156; CG5600; CG5891; DMbs; DMBS; Dmel\CG32156; DMYPT; l(3)03802; l(3)72Dd; l(3)j3B4; l(3)j7A1; l(3)S005331b; l(3)S057306; l(3)S057306b; l(3)S095304; mbs; MBS; Mypt" /note="Myosin binding subunit" /map="72D1-72D1" /db_xref="FLYBASE:FBgn0005536" /db_xref="GeneID:49070" CDS 768..4505 /gene="Mbs" /locus_tag="Dmel_CG32156" /gene_synonym="0573/06; 0953/04; CG32156; CG5600; CG5891; DMbs; DMBS; Dmel\CG32156; DMYPT; l(3)03802; l(3)72Dd; l(3)j3B4; l(3)j7A1; l(3)S005331b; l(3)S057306; l(3)S057306b; l(3)S095304; mbs; MBS; Mypt" /note="CG32156 gene product from transcript CG32156-RN; CG32156-PN; Mbs-PN; lethal (3) S095304; lethal (3) S057306b; myosin binding subunit; myosin phosphatase-binding subunit; lethal(3)72Dd; myosin-binding subunit; MLC-phosphatase; myosin phosphatase target subunit" /codon_start=1 /product="myosin binding subunit, isoform N" /protein_id="NP_001246785.1" /db_xref="FLYBASE:FBpp0300534" /db_xref="GeneID:49070" /db_xref="FLYBASE:FBgn0005536" /translation="MSSLDARNNSAMMKRAEQLKRWEESDTNRAAPTPRHEHGRRIKF SSGCVFLAACLSGDKDEVVQLLDQGADINTANVDGLTALHQACIDDNLDMVEFLVERG ADINRQDNEGWTPLHATASCGFVSIARYLVENGADVAAVNSDGDLALDLAIDVQHMAM IDYMEKMVQELNINVDEARKAEELAMLNDAKKWLRSDAAEVDRPHPKTGATALHVAAA KGYTKVLGLLLAGRGNVDRQDNDGWTPLHAASHWGQRETAEMLVESLADMDIRNYAGQ SCIDVADRKIVKFLEELRANKRNKRRPSSQISRISDAMENHVEKTPTKLVRVEVRTDA TKDAENVKPNQQIHAVEHPVEEEAPWRRKLPRTPSDSPTNNQVPDRELGTNSSETAND VILRRTQSFENDQKFYQKYNELRARIKANSCPILPANANANAAAANKSNNNNNLSSNN YHNNNNNNNKSDLLLGYAAGTTTTTSTPTTTTTTTSSTFNNTHSNTNNTSTTQQQPAA AAAASAANQLYSVQRSASLKDNSMYYRKPTVTIATSTAATAINSPSTTVQTPPIRSQV TAKIAEKSNNGSSSTASVSDAESSKPPPKQSASNMIKNFFKSFVPPVRDEESETQRKA HAKRVRETRRSTQGVTLDEIKSAEELVKKKNMGMANNNNNNNISTTTTNTISNSGNET SSASSTSAPTPSILGSNEQQDELQPPPPPTTPPPAVIPTTTTATDETEIEEVVSSPPA GQSQNDTTASFTLSAPVRRSLSTEGEADANSDPEGDQDQTVVSASYTIMPRRERLPES SENVESIRSPQKTEPVAKSSSEDKSEEPPHARPTDLPLIPAPAAPSTEAIKSSSAATT PAALESPVRLRDKRGLSGSQESETKSDTASPVSSHPDFNARDSLLSLYARRTTDSSAG GGGVGGGAGVGAGGASGAATSSSTSAAERRPSWRLKFDAGSKFKLEDITSGGTYPPNN STIIPSAPAVMAAANLSTTTGVQRRISSGPIALNASNQSLNSVGRPVSAPSEGTNNSA YVTPSARKFETNATSTGATTAATTTSNSTSNSVSATSANHTTATAPNATSNHDDKDND KENDNRTQTVIQRRRKPKRRSTGVVHIDMDELDPERQNESSNNDNEEKEKESGSERTS RSRLGSTASTATTSESKSSSSNDKTENGDGIDYKALWEAEKLENDKLRQMLKQKDDEA VQTRATLERFANAQLDAYKSDNHRLKEENAALIRVISKLSK" ORIGIN 1 cctccgattc acatcgtcaa aaaattttgg tctgtgaact tcgtgcggat gaaattcgat 61 ttgaacgcca ccgaaaatat gcaaaataaa gtgaaatacc agtgcctcgc ggacgaggag 121 cgcttcagcg gagagtcctg cagccattaa agcccagaga gcactgaaag ttctgggaat 181 ttcgcgggaa aggtgcgttt ttcgcttggt ctttcgtttt tgccccatcc tcttgtgtaa 241 tttccattga atgcaacaac aaaggtgcgc gttaaacaac aacaaatagc attgttttgc 301 gggagagcga gtgtgagaga gagagagcgt tcctgattgc gacattgtgt gagtgagcgg 361 agaagaaaac gccaagaagt tggctgataa agcaaacgca cacgcacgca cgcacgcgca 421 cacacacgca aagaaaatag aaaaatcgta aaataataat aatcagcaag caggaaaaga 481 agaagcagca gcagcagcag tacaaacagc aaaagtgtag tcgtgatcga aaatcgaaag 541 tgtgaagcat tttctataaa tagtgcaaaa tcaaaaccca attcccattg caaacaaaag 601 cgcaataaag caattacgat agagcaatag cgatacaaca gcgctacata caaaatctac 661 acacatctgg agcagtcgag cgatctcaca gagcgcgtgc tctgcagcaa gtagcaggat 721 tatctgaagg agcagatcgt tcgtctggcc aagaaggatc tgccaagatg tcctcgctgg 781 acgcacgcaa caactcggcg atgatgaagc gcgccgagca gctgaagcgc tgggaggagt 841 cggacacaaa ccgcgccgcc cccacccccc ggcacgagca cggccgcagg atcaagttca 901 gctccggctg tgtcttcctc gccgcctgcc tttccggcga caaggacgag gtcgtccagc 961 tgctcgacca gggcgccgac atcaacaccg ccaacgtcga tggactcacc gccctgcacc 1021 aggcgtgcat agacgacaat ctggacatgg tggagtttct agtggagcga ggtgccgaca 1081 taaaccgcca ggataacgag ggctggacgc cactgcacgc cactgcctcc tgcggatttg 1141 tgagcatagc tcggtatttg gtggaaaatg gcgctgatgt ggccgctgtg aacagcgatg 1201 gtgatttggc cttggatttg gccatcgatg tacagcacat ggccatgatt gactacatgg 1261 agaagatggt gcaggagctg aacatcaacg tggatgaggc tcgaaaggcc gaggagctgg 1321 cgatgctgaa cgatgccaaa aagtggctga gaagcgatgc cgccgaggtg gatagaccgc 1381 acccgaaaac gggagccaca gccctccacg tagccgccgc aaagggttac acgaaagtgc 1441 tgggtctgct cctggccgga cgtggcaatg tggatcgtca ggataacgat ggctggacgc 1501 cactgcacgc ggcatcgcat tggggtcagc gggagacggc cgagatgctc gtggagtcac 1561 tggccgacat ggatatacga aactatgccg ggcagtcatg catcgatgtg gccgatcgca 1621 aaatagtcaa attcctggaa gaactgcggg ccaacaaacg caacaagcgg cgaccatcta 1681 gtcaaataag cagaatctca gatgcaatgg aaaatcatgt ggagaagacg cccactaaac 1741 tggtgcgcgt tgaagtgaga actgatgcca caaaggatgc tgagaacgtg aagcccaacc 1801 agcagatcca cgccgtcgag catccagtcg aggaggaggc gccatggcga cgcaaactgc 1861 cccgcacacc cagcgatagt cccactaata atcaagttcc tgatagagag ctcggcacca 1921 atagctcgga gaccgccaac gacgtcattt tgcggcgcac gcaaagcttt gagaacgatc 1981 aaaagttcta tcaaaagtac aatgagctgc gggcacgcat aaaggccaat tcctgtccca 2041 ttttgccggc gaatgcgaat gctaatgccg ctgctgccaa caaatccaat aacaataata 2101 acctaagtag caataactat cataataaca acaataacaa caacaaaagc gatctgctat 2161 tgggatatgc tgctggcacc acaacgacaa caagcacccc cacaacaaca acaacaacaa 2221 catccagtac attcaacaac acccactcga acaccaacaa cacaagcaca acacaacaac 2281 aaccagcagc agcagcagca gcatcggcag caaatcaatt atatagcgta caaagatcgg 2341 cctcactcaa agataactca atgtattaca ggaaaccgac cgttacgatt gcaacgagca 2401 cagcagccac agcgatcaat tctccatcga caactgtaca gaccccacca attcgcagcc 2461 aagttacagc gaaaatagca gaaaagagca ataatggcag ctcgtccacg gccagtgtca 2521 gcgatgcgga gagctccaag ccaccgccca aacaatccgc gagcaatatg atcaagaact 2581 tcttcaaatc ctttgtgcca ccggtgcgtg atgaagagag cgaaacgcag cggaaggcac 2641 atgctaagcg tgtgagggag actcgacggt ctacccaagg tgtcaccctg gacgagatca 2701 agagtgccga ggagctggtt aagaagaaga acatgggcat ggccaacaac aacaataaca 2761 acaatattag caccaccacc acgaacacga tcagcaacag cggcaacgaa acaagctctg 2821 catcatcgac atcagctcca acaccatcga tcctcggcag caatgagcag caggacgagc 2881 tgcaaccacc gccaccgccc accacaccac cgccagctgt aatacccacc acaacaacgg 2941 ccaccgatga gacagagatc gaggaggtgg tgtccagtcc tccagctggc caaagtcaaa 3001 acgataccac tgctagtttt acgctatcgg ctcccgtgcg aagatcgctg tcgaccgagg 3061 gcgaagccga tgccaatagt gatccggagg gtgatcagga tcagacggtg gtcagtgcca 3121 gctatacgat aatgcccagg cgggagaggc ttcccgaaag ctccgagaat gtagagagca 3181 taagatcgcc acaaaagact gagccagttg ccaaaagttc cagcgaggat aagtccgagg 3241 agccaccaca tgccaggccc acggatctgc cactaattcc ggctccagct gctcccagca 3301 cagaagctat caaatcatcc tcggcggcca ctacgcccgc tgccctcgag agtccagtgc 3361 gcttgcggga taagcggggt ctgtccggca gccaagaatc ggaaaccaag tccgataccg 3421 cctcgcccgt gtcctcacat ccggacttca atgcccggga ctcgctactc agtctatacg 3481 cccgtcgcac aacggacagc agcgcgggag gcggaggagt tggtggtggt gcaggtgtag 3541 gtgcaggtgg tgcaagtgga gctgcaacct cgtcttcaac ttcggcagcg gaacggcgtc 3601 cgtcttggcg cctgaaattc gatgccggct ccaagttcaa gttggaggac ataaccagcg 3661 gtggcacata tccgcccaac aacagcacca tcatacccag tgctccggcg gtaatggcag 3721 ccgccaactt atcaaccaca actggtgtcc agcggcgcat cagcagcggt cccatcgcac 3781 taaatgcttc caatcagtcg ctcaactctg tgggtcgtcc agtttccgcg ccaagcgagg 3841 gcaccaacaa cagtgcctat gtcacgccct cagctcgcaa attcgagacg aacgccacgt 3901 ccacgggagc gaccactgca gcgaccacga ccagcaactc aacctccaat tcagtgtctg 3961 caaccagtgc caatcataca acggctacgg caccaaatgc cacgtcaaac catgacgata 4021 aggataatga taaggagaac gacaatcgca cacagacggt tattcagagg cggcgaaagc 4081 cgaagcgcag atcaacgggc gtggtgcaca tcgatatgga tgaactggat cccgagcgac 4141 agaacgaatc gtccaacaac gacaacgagg agaaggagaa ggagagtggc agtgagcgga 4201 catcccgttc ccggctgggc agcaccgcga gtacggccac caccagcgag tcaaagagct 4261 ccagcagcaa tgacaagacg gagaatggcg atggcattga ctacaaggcg ctctgggaag 4321 cggaaaaatt ggagaacgat aagctgaggc agatgctcaa gcagaaggac gatgaagccg 4381 tccagacacg tgcaacactc gagagattcg ccaatgccca actcgatgcc tacaaatcgg 4441 ataatcatcg cctgaaggag gagaacgccg cgttgattag agtaattagc aaattaagta 4501 aatgaaatta tgttttactt tcagtgtatg tatgtctgag aacctatatc atcgagaagc 4561 aacaatttta ctttagttac cagctggaag aaggctgaaa aagaatgaaa atgaatgtta 4621 aagccagcaa gccgatgcaa gcgaaagccg gatattcgcg tgaaaatttc aaaatttgtt 4681 tattatttgt gttaggccgt taagcattag gtgaaaccat gtttcaaata tcgttgagaa 4741 ttgttttgtt cgttttatat aaagaaatct tatgtatttg gtcaaatttt atatacaaaa 4801 tagagcaaat tataaataat aaacttacac aaatcaagct taactatatt tacataagca 4861 tacgcaacgt gtataacgat cagaagatca aaagaaatga aatggaaagc gaaaaccttt 4921 acatacaaac tgagaacata atcatcaaat gagccctagt tacattacag attagtttaa 4981 ctacatgata catataaata catgaatata tatatatata ttttttcata tataaattat 5041 atatacacat tacataatac atatatattt aaagcaacag aatcataagt tcaacatgtc 5101 aatgtgtaat atcatcgagg atccagaccg ccagttcatg agactccgga gatgtgtcga 5161 aaccagccca cgcgtcaact tactaagtgt aatcattatc atccaattgt aattgttttt 5221 agtgctgcac agataaaggc atcggtgata ccatcaaaag ctatagtagc tacatatata 5281 gtataccctt caactgagga gacaatttcg caaaagctcc atggcgctat cctatagatc 5341 gggatgggtt catcactgcg tatgcccaat tatttctatt atattgttat ttgagtacgt 5401 taagataagc agacactttt agttctctcc ttcacttcga aacgtattat atacatttac 5461 atcgtactat attttacttt cgcttataac gaaacaaatg atcatacgca tatgcatatt 5521 tctgttattt attaaattcg cctaagagat tttgtgttac tcgtaaatgg aaacgataat 5581 caagcataaa caaccataag aacgtgaatt gtgtaatatg taaaattgtg tgagaaaata 5641 tttatgaaaa tttgattcaa atacgaaact taataaatgt gatcgc //