Dbfetch
LOCUS NM_001259599 11632 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster rhinoceros (rno), transcript variant D, mRNA. ACCESSION NM_001259599 VERSION NM_001259599.2 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 11632) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 11632) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 11632) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 11632) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 11632) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 11632) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 11632) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 11632) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 11632) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 11632) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 11632) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 11632) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 11632) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 11632) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 11632) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (10-NOV-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 11632) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 11632) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 11632) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 11632) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 11632) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 11632) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 22 (bases 1 to 11632) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 11632) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 24 (bases 1 to 11632) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 25 (bases 1 to 11632) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jan 16, 2013 this sequence version replaced NM_001259599.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..11632 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="3L" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..11632 /gene="rno" /locus_tag="Dmel_CG7036" /gene_synonym="CG7036; Dmel\CG7036" /note="rhinoceros" /map="61B2-61B2" /db_xref="FLYBASE:FBgn0035106" /db_xref="GeneID:38027" CDS 565..10290 /gene="rno" /locus_tag="Dmel_CG7036" /gene_synonym="CG7036; Dmel\CG7036" /note="CG7036 gene product from transcript CG7036-RD; CG7036-PD; rno-PD; rhinoceros" /codon_start=1 /product="rhinoceros, isoform D" /protein_id="NP_001246528.1" /db_xref="FLYBASE:FBpp0294000" /db_xref="GeneID:38027" /db_xref="FLYBASE:FBgn0035106" /translation="MSQRGKRGNQQHHQSHHPPPQQHQRKDVEPQPPPTKRRKGRPPN GATTAAVAEVTGSGPATGSERVPVLPLCKSKHEEPGAEAGGGGQGRAAAGATSTSKSK STKLAKSASKCKSQGASSSSSWQARSVADIKMSSIYNRSSTEAPAELYRKDLISAMKL PDSEPLANYEYLIVTDPWKQEWEKGVQVPVNPDSLPEPCVYVLPEPVVSPAHDFKLPK NRYLRITKDEHYSPDLHYLTNVVALAENTCAYDIDPIDEAWLRLYNSDRAQCGAFPIN ATQFERVIEELEVRCWEQIQVILKLEEGLGIEFDENVICDVCRSPDSEEANEMVFCDN CNICVHQACYGITAIPSGQWLCRTCSMGIKPDCVLCPNKGGAMKSNKSGKHWAHVSCA LWIPEVSIGCVDRMEPITKISSIPQSRWSLICVLCRKRVGSCIQCSVKPCKTAYHVTC AFQHGLEMRAIIEEGNAEDGVKLRSYCQKHSMSKGKKENAGSHGGGSASVASAMQKAN RYGSGAGGGADDGNNACGTTGEDPRRRKNHRKTELTSEERNQARAQRLQEVEAEFDKH VNFNDISCHLFDVDDDAIVAIYNYWKLKRKSRHNRELIPPKSEDVEMIARKQEQQDME NHKLVVHLRQDLERVRNLCYMVSRREKLSRSLFKLREQVFYKQLGVLDEMRLEKQQTK QEQQQPVMDLNAVIYANDGPTLYDRFYSSVGGQTVPAQYQDLKYILEQLMGKLQSGKQ GRGRASQSPNKRKQPAKASPNKKLNNGILSSRTSSPEKTVAGSKVGTTTSKVRSPPGK NPTGRRASKSSAAAATSTHNKSQFHSNIRSSTTSHSSSGTISSGNSSSANGTSSSDSS SGSDSGSESGSSSAGSGVSKRKSSSGSPLKKQSYARSVEQRQKQRQRRQNEAVAGASA TYPDSRSASSSSDGEDERCRNRQEPERGARRGPIQSKSVPNRSQASRSKPTTEADVGE GTGASARRKLSTTTRGLAQMDKDADESVSSDESEELLPLRGERQRESTTTSGLATTGS AIGRNLGQHIYSDSESSSSEQEKDQEEQATVESNVSDSQNQQTIRTKAAMKEFVPGTA ATTSSTSQAASSTSKAKNTREGKEGAASIGNSTKTKPNPNAKLYPADLLVVPQRQAAK KASENMRSTNLATTLQPDVSDRVREPDINSISGTAKSKVKDSSSRVSNEADKSSLEKV RPKEHLQKTVGKTSESAPAERGKRGRPPKVPKDARPPSITENDKPALPTHTQSKPPSV VATPVSAKSNFAVSLVPQRQAAKKAAEQLKSSKPVLESFSTGNDISDKETVTSATISG SGSSVPAASTPVKPTRRSSIKEAPITPKEPLSGRRKSKEDLLATPIKTTPLVKRRVVV PNLSSSSSGDSESSSSSSSSGSSSSSGGSDSDSESQASNSENPSSREPPVAPAKVPSD SSLVPKRSPRKSMDKPSALTIAPASVNVLNIPSTRSRQNSTTKSTKVALQKAVQSVED DVKCTPKTNRLQGSMDECGKQVQLEQATKRATRGSKSRPPSPTAKSSPEKTVSRCKSR AEESPKKVANLEQEISQRKVASGKGTSSLDKLLNKKQQQMNHSAQATPPPISPTPPAS ETRIVKDQCDLKPDEVSIQQINLGADAQPEPDLDPESAAEAGELPMDIDEELTTAPTR TQLSASASKLADIIDDERPPAAPLPASPTPTPTSNDEMSDAGSDLSERRRMRWRSRRR RRRRSHEPDEEHTHHTQHLLNEMEMARELEEERKNELLANASKYSASTSSPAVTVIPP DPPEIIELDSNSAEQQQQHLHDQPLPPPLVVQSPAADVVPTVMQQQLLPSQRPLIEQL PVEHLPIVETILEMEDSKFANNFASNLASVLNPPNQMSLIGSSIDRSKQISEEDSIQA TRNLLEKLRKTKRKAQDDCSSKEAVDLLPPTPAIPSVFPFHNAADPEDIIHAQKEQQH QQQQQLQSSQTCIYGNSSGPNSVASLTIKDSPMTANSGSYANSLTNTPNATPTNATMN NLGYQVNFPNSQPPPTLGLFLEKSPHQKGACPLSSNGGANVGQPAPTPDFVDLAAAAV KNTLGSFRGAATVPTQSGTGVNAKINDYDESTRMQSPFGGMPWNESDLIAERRSSSPS SVSESNDPPQPPPVVTATATTARSLAQLESCKNFFNSYPSGNAGPGTAANATAPFNHP PMVNGIDSIPMFNNTNTTQHQPTTPAHQQQQQRTPNNQYNGTIYPQLAGIMHPQTTPT EPPSSLYGNGGVGGAVQSTTLPPPAQVNQYPGTPYSATTLGMISVQQPALSTVPVQTA TTPNNPFTLTSPIDGKMPTYPAQLLSSCAEAVVASMMPPTPPVTATAKDSPSKRTSVS GSNLSKKQTHKSPQLPQGKSPGKSPRQPLQPPTPPAPVPVVALPPTKYDPQTHTLQGK PRQRAPRGSGGSGAPGRGRGRGRGRGRGGGVTSGMAMVLPPPMSDYGSNTHIVNNLVG TPFEFNNEFDDMAGPGVENLQSLRDRRRSFELRAPRVQNKPTTTPTTATTTNPLLHPV LPGPVDMRTYNLGFEAPHSTASQEAYQNNLLGAFDSGTADQTLSEFNEEDERQFQSAL RATGTGTSPSKQHSGPTALVAPPTGPNPTPAPNLLLHCTEANQMAPNVAATGAATHLV EGSLVEASLEATSEEVSIDSDSTIPHSKTSTSDARSQIKLKIKSPMAYPEHYNAMTNS SSLTLTSTLVQSSNVVQTTVSTSTVVSASSAVSGNSRRMRKKELLSLYVVQKDNHNDD SSCGLPAASDTLPLENLRKSEEEDELSGGNGTKRFKKNSSSRELRALDANLALVEEQL LSSGAGACGGGSSGDGRRRSACSSGSNNDNNGKTGAASSAGKRRGRSKTLESSEDDHQ APKLKIKIRGLTANETPSGVSSVDEGQNYSYEMTRRACPPKKRLTSNFSTLTLEEIKR DSMNYRKKVMQDFVKGEDSNKRGVVVKDGESLIMPQPPTKRPKSSKPKKEKKEKKRQK QQQLILSSSTTTMTTTLIENTASASPGDKPKLILRFGKRKAETTTRTASLEQPPTLEA PAPLRFKIARNSSGGGYIIGTKAEKKDESTADNTSPITELPLISPLREASPQGRLLNS FTPHSQNANTSPALLGKDTGTPSPPCLVIDSSKSADVHDSTSLPESGEAAMGVQSSLV NATTPLCVNVGNYENSNNSLPSASGTGSASSNSCNSNSINNNGSGGGRASGEGGLLPL KKDCEVR" ORIGIN 1 gagaaaaata atttttgctc aaaaataaaa taaataatca aaagaattgt aattcctgcg 61 aacgcaaatg cgattttggg aaacgtgagt ttgatacgga cgcttcacga aatgcgaaga 121 ctgtgagcgg tcttcgacta gcgaatgctc gtcgagaatc caaaccagtg agccaaacgc 181 caaagaaaaa cttgcaaaag tctgtggata aacaacgaac aataacaaaa ggcagcaagc 241 ggaaggtggc agtggaagtg gactaactcg cccgtggaga agtgcggagc acacaggact 301 gcaaagtggc gtcgctactg gatattaggg ctggggcagc agcggcgtcc atgtccacgg 361 ggcacaaagg gtggaccacc aagaatcacg accgcaccac atccaggaga gcgcagcagc 421 agcagccggt gtggtgtcgc caactgtggc cttaagcatg tagtcttgca gcaaagaacc 481 cgttctctaa caagcacaag acacaaggga caaggtacca atcgaagcaa aaacacacaa 541 atatccaatc aacaccaatg aaaaatgtca caaagaggta agcgcggtaa tcagcagcat 601 caccagtcgc accatccgcc gccgcaacag catcagcgca aggatgttga gccgcagccg 661 ccgcccacca agcggcgcaa aggtaggcca cctaatggag ccactacggc agcagtagct 721 gaagtgactg gatcgggtcc agctacagga tcggagcgtg tgccagttct gcctttgtgc 781 aaaagcaaac atgaagagcc aggggcggaa gcggggggag gaggacaagg aagagccgcg 841 gcaggcgcta ccagcactag caaatcgaag tcaacgaaac tggcaaagtc ggcaagcaag 901 tgcaagtcgc agggggcgag ttctagtagc tcctggcagg cgcggtctgt agcggacatc 961 aagatgtcga gcatctacaa tcgaagctca acggaagctc cagctgaact ttaccgcaag 1021 gatctcatta gcgcaatgaa attgccagac tctgagccgt tggccaacta cgagtattta 1081 atagtaacag acccatggaa gcaggaatgg gaaaagggtg tgcaagtgcc cgttaaccca 1141 gactcccttc ctgagccatg cgtctatgtt ctgcccgagc ctgttgtgtc tccagcgcac 1201 gactttaagc tcccgaaaaa tcgctatctg cgcattacca aagacgagca ctactcgccg 1261 gatctgcatt acctgacgaa tgttgttgcc ttggcggaga acacatgtgc ctatgatata 1321 gatcctattg acgaggcctg gttgcgtctc tacaacagcg atcgtgccca atgtggtgct 1381 tttcccataa acgcgacgca gtttgagcgc gtcattgagg agctagaggt tcgttgctgg 1441 gaacagattc aagtcatact taaactggaa gaaggcttgg gcatcgaatt cgatgagaat 1501 gtcatctgcg atgtttgccg atcgcccgac tccgaggagg cgaacgaaat ggtattctgt 1561 gataattgca atatctgtgt gcaccaggcg tgttatggca ttacagcaat tccatcagga 1621 caatggctat gccgcacttg ttcgatggga attaagccgg actgtgtcct ctgtccaaat 1681 aagggcggcg ctatgaaatc caacaagtcg ggtaagcact gggcacacgt ctcttgcgct 1741 ctgtggatac ccgaggtcag cattgggtgt gtggatcgca tggaacccat cacgaaaatc 1801 tctagcattc ctcagtcgcg ttggtccctg atctgtgtac tctgccgaaa gcgagttggc 1861 agctgcatcc agtgctcagt aaagccctgc aaaacagcat accatgtgac ttgcgcgttt 1921 cagcatggcc tggaaatgcg tgcaatcata gaggaaggta atgctgagga cggcgtgaag 1981 ctgcgctctt attgtcagaa acacagtatg agcaagggta agaaggaaaa tgctggtagt 2041 catgggggag gcagtgcctc agtcgcaagc gccatgcaga aagcaaacag atacggcagt 2101 ggggctggtg gaggagccga cgacggcaac aacgcgtgcg ggacaactgg agaggatcca 2161 cgcaggcgga aaaatcaccg taaaaccgaa ctgacctccg aggaacgtaa ccaagccaga 2221 gctcagcgcc tccaggaggt ggaagctgag ttcgataagc atgttaactt taatgacatc 2281 agttgccatc tatttgatgt cgacgacgat gctattgttg ccatatacaa ttattggaag 2341 cttaagagaa agtctcgaca caatcgcgag cttatcccgc ccaagtccga agatgtggag 2401 atgatagccc gcaagcagga gcaacaggac atggaaaatc ataagttggt ggtgcatttg 2461 cgacaggatt tggagcgagt tcgtaatctc tgctatatgg ttagtcgaag agaaaagctt 2521 tcgcgctctc tctttaagct acgtgagcag gtattctaca agcagctggg agttctggat 2581 gagatgcgct tggagaagca gcagaccaaa caagagcagc aacaacctgt gatggatctg 2641 aacgctgtaa tctacgccaa cgacggacct actttgtatg accgtttcta cagctctgtg 2701 ggaggacaaa ctgtgccggc gcagtaccag gatttgaaat acatccttga acagcttatg 2761 ggtaagctgc agagtggtaa acagggccgt ggccgtgcct cgcagtctcc taacaaacgc 2821 aagcagcctg ctaaagcttc gccaaacaag aagcttaata atggcattct tagttcacgc 2881 acgtcatcgc ctgagaagac tgtggcaggg agtaaggtgg gaacgactac atccaaggta 2941 cggtctccgc cagggaagaa tcctacaggg aggcgtgcct cgaagagcag cgcggcggcg 3001 gcgacgtcga cccacaacaa aagtcaattc cactcaaata tccgcagtag cacgacctcc 3061 cattcgtcaa gcggcactat atcatcaggt aattccagct cggcgaatgg taccagcagc 3121 tccgatagtt cctcaggaag tgattcgggt agtgaaagcg gtagctctag cgcgggtagc 3181 ggagtctcca agcgaaagtc ttcctcagga agtcccctta aaaagcaaag ctacgctcgg 3241 tccgttgagc agcggcaaaa acagcgacag cgacgtcaaa atgaagcagt tgcgggtgcg 3301 tctgcaacgt atccggattc caggtctgca agcagctcca gcgacggtga agacgagcga 3361 tgtagaaacc gccaagaacc agagcgcggt gcgagacggg ggccaattca aagcaaatca 3421 gtacctaata ggagccaggc aagtaggtca aaacctacaa cggaagcaga cgttggagag 3481 ggaactggag cctctgcaag acgaaagttg tctacgacaa cacgaggact tgcccaaatg 3541 gataaagatg ccgatgagag cgtatcgagc gacgaaagtg aggaattgtt gcctctaaga 3601 ggggaacgac agcgtgagag cacaacgact tccggactag ccacgactgg ttcggccatt 3661 ggtagaaact tgggacagca tatctactcc gactctgaga gcagttcctc tgaacaagaa 3721 aaagaccagg aggagcaggc caccgtggaa agtaatgtta gtgactcaca aaaccaacag 3781 acgattagaa caaaggcagc tatgaaagag tttgtgccag gaacagcagc cacaacatcc 3841 tctacttccc aagcagcgtc ctcaactagt aaagcgaaga acacgcggga aggaaaggaa 3901 ggggctgcca gtatcggcaa cagtacaaaa accaaaccga acccgaatgc caagttgtat 3961 ccggcagatc ttttggtggt gccacagcgc caggcagcca aaaaggcttc tgagaacatg 4021 cgatccacaa atctcgccac gacgctacag ccagatgtgt ccgacagagt cagagagcca 4081 gacataaact ccatttcagg aactgcaaag agcaaggtga aggattcaag ctctcgtgtg 4141 tcgaatgaag cggataaatc aagtcttgaa aaagtacgac caaaagaaca cttacagaag 4201 actgttggaa aaacgtccga aagcgcacct gctgaacgtg gaaagcgcgg aaggccacca 4261 aaggtcccaa aggatgcacg tccgccatct attacggaaa atgacaagcc tgccctccca 4321 acgcatactc aaagcaagcc cccatctgtc gtcgctaccc cagtctcagc caagtcgaac 4381 tttgcagtct cattggttcc tcaacggcaa gcggctaaga aggcagcgga gcaattaaag 4441 agtagcaaac ccgttctaga atctttctca acggggaacg acatttcgga caaagaaaca 4501 gtgacgtcgg caacgatatc cggatcagga tcatctgttc cagcggctag cacgccagtt 4561 aagcctacca gacggtcctc aattaaagaa gcaccaatta ctccaaagga acccttaagt 4621 ggcagaagaa aatcaaaaga agatttgctg gcgacaccta taaaaacaac tcccctggtt 4681 aagcgccgcg tagttgtccc aaatctttca agttctagtt ctggcgacag tgaaagttcc 4741 agctcctcta gcagctcagg aagtagttcc agcagtggcg gcagcgactc ggacagcgag 4801 tctcaggcca gcaattcgga aaacccatct agtagggagc ctcctgtagc ccctgcgaaa 4861 gtgccatctg attcctctct tgtgccaaaa cgttcacccc gcaagtctat ggataagcct 4921 tcagcattaa ctattgcgcc agcatcggtc aatgtattga acataccgtc tacgcggtct 4981 cgtcagaact ctacaacaaa atcgacaaag gtagcactgc agaaggcagt gcaatcagtt 5041 gaggatgacg tcaaatgtac gccgaaaaca aatcgtctgc agggctctat ggacgaatgt 5101 ggaaagcagg tccagttgga acaggctacc aaaagagcga ctcgcggttc caagtcgcga 5161 ccgccctcgc ctactgctaa atcgtctcca gaaaagacag tatccagatg taaatctcga 5221 gcggaagaat ctcctaagaa ggttgcaaat ttggaacaag aaataagcca gagaaaagta 5281 gctagcggaa aagggactag ttcgttggac aagctgttaa ataagaaaca gcagcagatg 5341 aaccattctg ctcaagctac acccccacca atttcaccaa ctccacctgc ttctgaaaca 5401 cgtatcgtaa aagatcaatg tgatcttaaa cccgatgagg tgtccatcca acagattaac 5461 ttgggagcag atgcgcaacc cgaacccgat ctggacccag agtctgcggc agaagctggt 5521 gaactaccaa tggatattga tgaggagctt accactgctc caacgcgaac ccaactatct 5581 gcgagcgcga gtaaactggc agacataatc gatgatgagc gtccaccggc ggctccgctt 5641 cccgcctcgc ccactcctac ccctacctct aatgacgaga tgtctgacgc tggaagtgat 5701 ctcagcgaac ggcggcgtat gcgctggcga tcccgacgga gaagaaggag acgtagtcac 5761 gagccagacg aggaacacac tcatcacacc caacatctcc tcaacgagat ggaaatggct 5821 agggagctgg aagaggaacg taaaaacgag ctgcttgcaa atgcgagtaa gtactcggcg 5881 tctacatcct ctccagcagt cactgtgatt ccgcccgatc cgccggaaat aattgaactg 5941 gactcgaatt ctgcagagca gcaacagcag catctacatg accaacccct gccgcctccg 6001 cttgttgtac aatcccctgc tgcagatgtt gtaccaacag ttatgcagca acagctgctg 6061 ccctcacaac ggcctctaat cgagcaactg cctgtcgagc acttacccat cgttgagaca 6121 atacttgaga tggaggacag taagtttgct aacaacttcg cgtcaaactt agccagtgtg 6181 ttaaatcctc ccaatcagat gagtctaatc gggtctagta tagacaggag taagcaaata 6241 agtgaggagg atagcatcca agcaacccga aatctcttag agaaactgcg caaaacaaag 6301 cgcaaggcgc aggatgactg cagtagcaag gaggcggtcg atctattacc tccaactcca 6361 gccatcccat cggtttttcc ttttcacaat gcggcggacc cagaggatat cattcatgcg 6421 caaaaagaac agcagcacca acagcaacaa cagctgcaat catctcaaac atgtatttat 6481 ggaaactcat caggacctaa ctctgttgca tcattgacta tcaaggattc tcctatgaca 6541 gccaacagtg gaagctatgc aaacagtctc accaacactc caaatgctac acccaccaac 6601 gcaacaatga acaatcttgg gtatcaagta aattttccga actctcagcc acctccaacg 6661 ttaggtctct tcctggaaaa atcaccccac caaaaagggg cttgtcccct atccagcaac 6721 ggaggagcta atgtagggca acctgcaccc actcctgact ttgtagactt ggcagcagca 6781 gcggtaaaga acactctcgg aagctttcgc ggagcagcaa ccgttcccac gcaatccgga 6841 acgggagtca atgcgaagat caacgactac gatgagagca cacgaatgca gtcgccgttc 6901 gggggaatgc cgtggaacga aagcgatctt atcgctgaga gaagaagcag ctcgcctagt 6961 tcagtgtccg aatccaatga tcctcctcag ccacctccag tcgttacggc aacagcaaca 7021 acggctcgat ccctcgctca gcttgagagc tgtaaaaact ttttcaacag ctatccaagc 7081 ggtaatgccg ggcctggcac tgcagcaaac gctacagcgc cctttaacca tcctccaatg 7141 gtgaacggta ttgattccat accaatgttc aacaatacta atacgactca gcatcaaccg 7201 acgacgccag ctcatcaaca gcaacagcag agaactccaa acaatcagta caacggaact 7261 atctaccccc aactagcggg tatcatgcat ccacagacaa ctcctacaga accgccttca 7321 agcttatacg gcaatggggg agttggaggc gctgtgcagt ccactacact acctccaccg 7381 gctcaggtca accagtaccc cggaacacct tattccgcga ctactttggg tatgatttct 7441 gtacaacagc ctgcgctttc aacagttccc gttcaaactg caactacacc caataatccg 7501 tttactctga cttcgccgat tgatggaaaa atgccgacat atccggctca gcttctaagc 7561 agctgtgcag aagcagtcgt tgcgtcgatg atgccaccaa ccccaccggt tacagctaca 7621 gcaaaggact cgccaagcaa gagaacaagc gtcagcggta gtaacttatc taaaaaacag 7681 acgcacaaat cgccccaact tccgcaagga aaatcgccag gaaagtcgcc cagacagcct 7741 ctgcagccac caacgcctcc tgcaccagtt cccgtggtgg cattgccgcc gactaaatat 7801 gacccccaga cgcacacatt acagggaaag ccgcgccagc gtgcaccgcg cggtagcggc 7861 ggctctggag caccaggcag gggcagggga cgaggaaggg gtagaggacg tggaggagga 7921 gttaccagtg ggatggctat ggtactgcca ccgccaatgt cagattacgg gagcaatact 7981 catatagtca ataatttggt cggaactccc tttgagttca acaacgagtt tgacgacatg 8041 gcaggacctg gtgtggagaa tctgcaatcg ctaagggatc ggcgaagaag ttttgagctt 8101 cgagctccac gagttcaaaa caagccaacc actacaccga caactgcaac aaccacaaat 8161 cctctcctcc atccagtgct gccgggacct gtggacatga gaacatacaa tctcggattt 8221 gaggcaccgc acagtacagc atctcaagag gcctaccaga ataatcttct gggtgcgttt 8281 gactcgggaa ccgccgatca gacactcagc gagttcaacg aggaggacga acgccagttc 8341 cagtcggcac tgcgagcaac tggcactgga acctcgccca gcaaacagca ttcaggacca 8401 acggcactag ttgcacctcc aactggtccc aatcccacac ctgcaccaaa tcttcttcta 8461 cattgcacgg aagcaaacca aatggcaccc aatgtggctg ctacaggtgc tgctacgcat 8521 ttggtcgaag gctcgctggt tgaagcatct ctagaggcca cttcagagga ggtatcgatt 8581 gactcagaca gcacgatacc acactccaag acctcgactt cagatgcccg aagtcagatt 8641 aaacttaaga tcaagagccc gatggcctat ccagaacact ataacgccat gacgaacagc 8701 agcagtctga ctcttaccag cactctggtg cagtcgtcaa atgtagtgca aaccaccgta 8761 tccacgtcga ctgtagtcag tgcgtcatca gccgttagcg gcaactctcg tcgcatgcga 8821 aagaaggaac ttcttagtct ttatgtggta cagaaagata atcacaatga cgatagctca 8881 tgcggactgc cagccgcatc cgacactttg ccccttgaga atttgcgaaa gtctgaggag 8941 gaagacgaac tttcaggtgg caacggtacg aaaaggttta agaagaactc tagtagcagg 9001 gaattgcgtg ctcttgatgc gaacttagcc cttgtggagg aacaattgct ttcaagcggt 9061 gcaggagcct gtggaggagg atcatcgggt gacggcagac ggcgtagcgc ttgtagctca 9121 ggtagcaata acgacaacaa cgggaagact ggagcagcta gtagtgcagg taagaggcga 9181 ggacgcagta agactctcga aagcagcgag gatgaccacc aggcccctaa gctgaagatc 9241 aaaatcaggg gtttgacggc caacgagaca ccttcaggtg tttcaagcgt tgacgagggc 9301 caaaactaca gttatgaaat gacccgaagg gcttgtccac ctaaaaagcg tttgacaagt 9361 aattttagca ctcttacact agaggaaatc aagagggact cgatgaatta ccgcaagaaa 9421 gtcatgcagg actttgtcaa gggcgaggac agcaacaaga gaggggtagt tgtcaaagat 9481 ggcgagtcgc tcataatgcc ccagcctccc acaaaacgac ctaagtcttc caagccgaaa 9541 aaggagaaga aggaaaagaa acgccaaaaa cagcaacagc ttatcttaag cagcagtaca 9601 accaccatga ccactacgtt aattgagaac acggccagtg cgtcgccagg tgataagcct 9661 aagctgatcc tacgttttgg caaacgaaag gcggagacca cgacaagaac cgccagtctg 9721 gagcaacctc ctaccttgga ggctccagca cccctgcgat ttaaaatagc ccggaactca 9781 tctggcggcg gatacataat cggcacgaag gcggaaaaaa aggatgagtc tacggcagac 9841 aacacgtctc cgattacgga gctgccactt atatcacctc tcagagaggc gtcaccacag 9901 ggcagactgc tcaacagttt tacaccgcac tcccagaacg ctaatacgtc accagccctg 9961 cttggtaagg acacgggtac cccatccccg ccatgcttgg tgatagactc tagcaaaagt 10021 gcagacgtgc acgactccac atccctgccc gagagcgggg aggctgcgat gggcgtgcag 10081 tcgtcccttg tgaatgcgac cacacctttg tgcgtcaacg tgggaaacta cgagaatagc 10141 aacaactcat tgccatcagc cagtggcacc ggatcggctt ccagcaactc ctgcaatagc 10201 aactcgatca acaacaacgg cagtggagga ggacgcgcca gcggggaagg cggcttactt 10261 ccattgaaaa aagactgtga ggttagatga taatcggaga acgcgaaaac gtcgcatgta 10321 agcgtatcct gtaacttcgt tcattcaagc tttcgataat cccctccctt tgtgatttgg 10381 ttccttgccc tcgcccctat taaagtgtta gcttttatag tacatgagcg aactgcaggt 10441 ccttaatcga actttaaagt gtacagttag cttgtaagcc ccttaaccat tcttctatct 10501 gtctgtaact ggtttgttgt aatcgcatca gcgtaaagaa gatattatct ctacacacct 10561 atataatatt aatatgcata tagcacatta tgcgagaaac aaaaaatata aattgtacat 10621 ttttagaagc agattgtaca tttaaggctt tgtaaaatat tgtattaaag atataaaaga 10681 aacaaaaaag cagacacagt tgtgttgtct agcctaaaaa aaatccaaaa atgctctcgg 10741 tttaggttta taaagtttcc attcacctaa aaatccttcc acgcctccta ctcactaagc 10801 atgattgata aaccccagca tatataataa acactattta ttaataatta tttaataaaa 10861 tgtgtaaaat aatcgtaaaa tattagcaaa aagtgttaaa tgcgtgcaaa aagtaacaac 10921 aatttcaaca attgtagcta tagtcattaa ttgtagttct tagcgaaaat caaagtcggt 10981 tgaccctgac cgcaatctaa gtgcatataa tagtccctgt tcccaaacat gtgcgtagag 11041 agaaaaacaa aaattgaata actaaattcc ctatcatttc cgaaagggaa ttgtttgtat 11101 tttagcgttt aagaatgcaa cgtatcgaag aactccagag gaaagttaat gattgttttg 11161 cgttgtatga tgttaaagca atagtaacgt aggcaaaaga acactggttt tctataagca 11221 aaggtgcctg cagcctcgag cgaaatcaca caaaacaggc cgaagcaaga tgccatctaa 11281 aacagtactg tttggtaggt gtgattgcat tccagattcc gatcgcggaa cgatacacaa 11341 cgccccggtc cacctagact ttctgtattc ttttgtcgcc aatagttcaa gaaattactt 11401 cccatttagt tttcaattag cattgggcgt atctcgatta aaggggcaat acaaaattaa 11461 ataaaaaatc atttaaggaa cccagcaaca aatatttatt ctaaaataaa tccgcgaaaa 11521 ggcaaaaata gagaataact aatataattg tgtaaagaac caagcaagaa ataaatttag 11581 aagttaacga cacttctgta attgtaaata tttgtgcgca aaaaatgttt tt //