Dbfetch
LOCUS NM_001259098 7755 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster nicotinic acetylcholine receptor alpha5, transcript variant H (nAChRalpha5), mRNA. ACCESSION NM_001259098 VERSION NM_001259098.3 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 7755) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 7755) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 7755) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 7755) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 7755) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 7755) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 7755) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 7755) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 7755) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 7755) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 7755) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 7755) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 7755) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 7755) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 7755) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (10-NOV-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 7755) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 7755) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 7755) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 7755) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 7755) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 7755) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 22 (bases 1 to 7755) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 7755) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 24 (bases 1 to 7755) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 25 (bases 1 to 7755) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jul 15, 2014 this sequence version replaced NM_001259098.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..7755 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="2L" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..7755 /gene="nAChRalpha5" /locus_tag="Dmel_CG32975" /gene_synonym="AChRalpha5; anon-WO02059370.44; BG:DS05899.4; BG:DS05899.5; CG16878; CG32975; CG4498; CT14633; da5; daf; Dalpha5; Dmel\CG32975; lincRNA.128; lincRNA.S1055; nAChR; nAChRalpha-34E; nAcRalpha-34e; nAcRalpha-34E; Nic 34E" /note="nicotinic Acetylcholine Receptor alpha5" /map="34F2-34F4" /db_xref="FLYBASE:FBgn0028875" /db_xref="GeneID:34826" CDS 1864..4290 /gene="nAChRalpha5" /locus_tag="Dmel_CG32975" /gene_synonym="AChRalpha5; anon-WO02059370.44; BG:DS05899.4; BG:DS05899.5; CG16878; CG32975; CG4498; CT14633; da5; daf; Dalpha5; Dmel\CG32975; lincRNA.128; lincRNA.S1055; nAChR; nAChRalpha-34E; nAcRalpha-34e; nAcRalpha-34E; Nic 34E" /note="CG32975 gene product from transcript CG32975-RH; CG32975-PH; nAChRalpha5-PH; Dalpha5; nicotinic acetylcholine Receptor_34E; nicotinic acetylcholine receptor alpha 34E" /codon_start=1 /product="nicotinic acetylcholine receptor alpha5, isoform H" /protein_id="NP_001246027.1" /db_xref="FLYBASE:FBpp0301601" /db_xref="GeneID:34826" /db_xref="FLYBASE:FBgn0028875" /translation="MKNAQLKLTEVDDDELWLAVRLAHCSSNISSSSSTRTTSSNKRH NQQLTTLQPRSLSTKHHSNIASEQHNSQQQEPASKDEDVANHGRSNDQQTHLQQLDSS NMLSPKTAAAATAAGDEATTQQPTNIRLCARKRQRLRRRRKRKPATPNETDIKKQQQL SMPPFKTRKSTDTYSTPAAITSCPTATYMQCRASDNEFSIPISRHDRVSTATFAWVLH VLQVLLVSLQQWQLHVQQRSVLLFRRIAASTIAFISYLGSFAAQLRSSSSSSSNSSNS GNSSSTQILNGLNKHSWIFLLIYLNLSAKVCLAGYHEKRLLHDLLDPYNTLERPVLNE SDPLQLSFGLTLMQIIDVDEKNQLLVTNVWLKLEWNDMNLRWNTSDYGGVKDLRIPPH RIWKPDVLMYNSADEGFDGTYQTNVVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQR CEMKFGSWTYDGFQLDLQLQDETGGDISSYVLNGEWELLGVPGKRNEIYYNCCPEPYI DITFAIIIRRRTLYYFFNLIIPCVLIASMALLGFTLPPDSGEKLSLGVTILLSLTVFL NMVAETMPATSDAVPLLGTYFNCIMFMVASSVVSTILILNYHHRNADTHEMSEWIRIV FLCWLPWILRMSRPGRPLILEFPTTPCSDTSSERKHQILSDVELKERSSKSLLANVLD IDDDFRHNCRPMTPGGTLPHNPAFYRTVYGQGDDGSIGPIGSTRMPDAVTHHTCIKSS TEYELGLILKEIRFITDQLRKDDECNDIANDWKFAAMVVDRLCLIIFTMFTILATIAV LLSAPHIIVS" ORIGIN 1 caatgctgca cgggcatcgg gctcagttgg tgttccggtt tcgggttgtg ctgtcagttg 61 cctttttgca cagcggctga gcgattgagc gattgaacga ttgaacggtt ggacggctga 121 gcgctggagc ggttgagagt gtgccatcgg agccggagag tcctaacgcg ttgcccgtgg 181 cctgtgtccg catccgtatc cgtatctccg tgcgtctctc tccgggtgtg tgcgtgtgcg 241 tgtggttaag tgtgtgcctg ttgtctgtcg ctaacggtgc gcgcgcgtct gtctgtccgt 301 cggcacgcat tccacatgca atggatgcca gaactaatag cggatattgg aataaacaaa 361 tataaaatca catacataca aatttataag ctaagcaata tttaattcgg ttgagtgaaa 421 ttcacaagaa ataaatcaat tttaaagttc ttcaagctgc ggaaacaaat actaagccgc 481 gaaaactatt taatcgctga actgaataaa cgcataagcc cacgactaaa gcaattttgt 541 aattaaaaaa aaaaatggga aaccaaactg aaaatactag ttattaatta atggtgatgg 601 ctactcacaa gcaaactatt tgagccagtt gtaaatatta ataacataaa atgcatacac 661 acacccgaaa ttccaaactc acgtaatgtc aagagaatta taatatccat acataaataa 721 tacaaatata aaatccattt aaatacaaag tgttctatta tatagaaaac taaattcgca 781 aatgatgtat aagttctcga taagcaactg aaaaacgcac aagattgata caaattttta 841 ataatagtac attaaaacat aaggacagtt caagcacagc tcaattggct gatgaatcta 901 agtgaaattg aaaaaagtcg aataactcga tacatacata tacatacata atcgcatata 961 aataaataat aatcattatt gaatttaaaa taaattacat caacttcatt acttatcaaa 1021 caaaaattct gggagacaaa tttgataaaa aaagtttaaa ataatattaa tacgcataca 1081 acaagtctaa taaacgaacc agtaaaggga ataatagttc gacaagtaat tattcaatac 1141 aatcaacgca atccttgaat gccaattgga aaaacctttg attgcataac aaatggagaa 1201 gagatagaag cagccacttt tgcatccaca attaaggaag aagtcaagta aatcaataga 1261 aaccaaatgc tacaaagcac tgccatatac aactgcaacg gattgcatta ggagaactaa 1321 caattgagta gctcaacatt tatagcaaaa acaatacgaa atctagaata atatagcaac 1381 tactatacaa aatcggagac cacgaacaaa tgagggagaa aaggcaaaaa ggaacatcaa 1441 cagcggaata aagttatgaa aattggatga atgaagcatg aagcaagccc agaaacgaga 1501 aaaaagttgt ggtataaact tttattgtag gaaaacgcat aaaaataata gaaaaacgct 1561 cttcgggttg taaagaaaat aagaagacaa aagaaagaca tgaaaacgtt gcgaacaata 1621 aagcatatac ttgccatatt gatataaagg gaaatcgtga aaaggcggtg aaaatttcgt 1681 aagattagtt ggtattaagg gcagcccagg cacacagcta aaaagggaac taaaaaaacc 1741 ccgcacagaa caatgaaagc tgcagcagct ggataaggcc gacaaaaccg aaaattatat 1801 tattgtaatc tagtagagag cagacaacat atccgctggc aacaaccaac accgaaagag 1861 actatgaaaa atgcacaact gaaactgact gaagttgacg atgatgagct gtggctggca 1921 gtaagattag cgcactgcag cagcaacatc agcagcagta gcagcacaag aaccaccagc 1981 agcaacaaga ggcacaacca gcaactcaca acactgcaac caaggagctt aagtacaaaa 2041 caccacagca acattgcaag cgagcagcac aatagccagc aacaggagcc agcatcgaag 2101 gacgaggatg tagccaacca cggtagaagc aatgaccagc agacgcatct gcaacagcta 2161 gacagcagca acatgttgtc gccaaagaca gccgcagcag caactgctgc cggcgatgaa 2221 gcaacaaccc aacaaccaac aaacataaga ctgtgtgcac gcaagcgaca acgattgcgt 2281 cgccgacgaa aaagaaaacc agcaacccca aacgaaacag atatcaagaa acaacagcaa 2341 cttagcatgc ctcccttcaa aacgcgcaaa tccacggaca cctacagcac accagcagca 2401 ataaccagct gtccgacagc cacctacatg caatgtcgag ccagcgacaa tgagttcagt 2461 attccgatat cgagacatga tagagtatcc acggccacat tcgcctgggt gttgcatgtg 2521 ctgcaggtgc tgctcgtgtc gctgcaacag tggcaacttc acgtgcaaca gcgatcggtg 2581 ctactgttca gaaggatcgc agcgagcacc atcgccttca tttcctattt aggcagcttt 2641 gcagcgcaac tgaggagcag cagcagtagc agcagcaaca gcagcaacag cggcaacagc 2701 agcagcacgc aaatattaaa cggacttaat aaacactcat ggatattttt attgatatat 2761 ttgaatttat ctgctaaagt ttgcctagca ggatatcatg aaaagagact gttacacgat 2821 cttttggatc cctataatac actagaacgt cccgttctca atgaatcgga cccgttacaa 2881 ttaagctttg gtttaacttt aatgcaaatt atcgatgtgg acgagaaaaa tcaattgcta 2941 gtcactaatg tgtggttaaa actggagtgg aacgacatga atctccgctg gaacacctcc 3001 gactatggcg gagttaagga tctgcgaata ccgccgcatc gcatctggaa gccggacgtg 3061 ctgatgtaca acagtgcgga tgagggattt gatggcacct accagacgaa cgtggtggtg 3121 cggaacaacg gctcgtgtct atacgttccg ccggggatct tcaagtcgac gtgcaagatc 3181 gacatcacgt ggttcccctt cgatgaccag cggtgcgaga tgaagttcgg cagttggacc 3241 tacgacggat tccagctgga tttacaatta caagatgaaa ctggcggtga tatcagcagt 3301 tacgtgctca acggcgagtg ggaactactg ggtgtgcccg gcaaacgtaa cgaaatctat 3361 tacaactgct gcccggaacc ctatatagac atcaccttcg ccatcatcat ccgccgacga 3421 acactgtact atttcttcaa cctgatcata ccttgtgtac tgattgcctc catggccttg 3481 ctcggattca ctctgccgcc agattcgggt gaaaaattat cactgggtgt taccatcttg 3541 ctctcgctga ccgtgtttct gaatatggtt gccgagacaa tgccggctac ttccgatgcg 3601 gtgccattgc tgggtacata tttcaattgc ataatgttta tggtagcttc atccgttgtg 3661 tcaacgattt taatattaaa ttatcatcat cgaaatgctg atacgcacga aatgtccgaa 3721 tggatacgca tcgtgttttt gtgctggctg ccatggatat tgcgaatgag tcgaccagga 3781 cgaccgctga tcctggagtt cccgaccacg ccctgttcgg acacatcctc cgagcggaag 3841 caccagatac tctccgacgt tgagctgaaa gagcgctcgt cgaaatcgct gctggccaac 3901 gtactagaca tcgatgatga cttccggcac aattgtcgcc ccatgacgcc cggcggaaca 3961 ctgccacaca acccggcttt ctatcgcacg gtttatggac aaggcgacga tggcagcatt 4021 gggccaattg gcagcacccg aatgccggat gcggtcaccc atcatacgtg catcaaatca 4081 tcaactgaat atgaattagg tttaatctta aaggaaattc gctttataac tgatcagcta 4141 cgtaaagatg acgagtgcaa tgacattgcc aatgattgga aatttgcagc tatggtcgtt 4201 gacagactgt gccttatcat attcacaatg ttcacaatat tagccacaat agctgtacta 4261 ctatcagcac cacatattat tgtctcgtag ccatatgggc gaggtggtta ttgttattgg 4321 ttttattata aaatcaattt gttaattatt aaattaataa cgaaactctt taagtaaatt 4381 aaaactaaaa agacactaaa aaagcacaaa aaaataggaa aatacatgat aaaaaccatc 4441 aactaaataa tacatccaag aaaaaccaaa acaaaaaaaa caaaaaaaaa aaaacaatta 4501 aaaatcgtct ctgaaaacac aataatttaa ttataaactt ctcgtttaaa agtctttcat 4561 tcaaatcaaa cagacactaa acaaataaga gactaaacca acatcatata ctaaaacgtt 4621 aaaaattaac taattccaat tttcctaatt ctatacaaaa atctatataa tggtaaacca 4681 aagaaatccc ctcacttccc gcaagccccc acaagccagt atctagattt cttccattga 4741 atatatatat atatatatac atactataca tgtttgaaca gcaagcaaaa cgggtatatt 4801 ttctttttag atatgttata ttttatagga taagcgaggc gttttcatac aaatagttac 4861 atgggttttc gaaacttttt tttttgacag acttcaatgg aaagtgcagt ttttcaatgc 4921 agaacgaaca aaagcctccc ccaaaccttt taggaaaact tcaatttgtg agctttatac 4981 tcgtagtagg aaacgtaggt ggaaaatttg cgactcgttt acgatatgaa aacccaacgc 5041 attgagatct acaaaaggaa aaaccaaatt tgtatcttct tcttcagcat tgaagtccag 5101 tccagagatt tgttccgagc aactttttgc tagcaattag tacctaggcc aactaagtga 5161 ttacgccaca ttcccccctc taaacgaaac tgcatttccg aaacagaacc aattaaccct 5221 acatatccag tactgtgtgt ctagtgcccc ctccctcgtc ttaatttaaa ctgaatgtct 5281 aaaccaatcg aaaaataaat cgaaaaccaa atccctaagc gtaaaaacca aaccccgtaa 5341 accctaccaa aaccaataga ataaccaatc tgaattggaa ttaagaaaat ttactggaat 5401 ataaaagata aaatgaaaaa tcaaaacgat gcgaatgaaa atgggcgaac atgtgagtaa 5461 ttgacgagcg gcacagcaga tgaagatgag cccagaatgg cgctcagtaa atgaaatgca 5521 tccgacggat tgcatttcat gttgactggc gctgcacagg aaatgaattt ataaattaaa 5581 tggttgcgag caataatatc tgcgtgttga tgaattgcat gatttttggt gatgcaaacg 5641 atgatcgatc gaactattgt gcgaggtcca cgacaaaagg gcaagagttc gctccttcag 5701 cgcattgaga acagcgaacc tctgtattga tctcacgata ttttcatttt catttacatt 5761 ttcgtttgaa ctttcactct tctgttttga acaaatactc aaagttgagg caccagaaag 5821 caattcaaca cacaaaccga acttaactcg atagaaaatc agaggccaga cagaccaaca 5881 acaagtagcg cattcgagat atacatatgt atttaccaat aacaatgaac atcacagatc 5941 ccagaacaca taacatgccg gtgcatgggt aattatgtgc ttgctctggt attgagcgca 6001 caaaacatac tgataccaga ccacaacaac caaaacatat aaaccaagga gctttataca 6061 gatatatgta tgatatatat atgacggagt tagcgtgggt ccatctgacc cgacttttca 6121 tatatttgta ccacacacaa aaaccacaca ggacacacaa acggttgttc gatggccagc 6181 ttatgccaat ttgtatgttt ctgtccgcca actagccaag cacacaattt catgatgaca 6241 agacaaggaa tacaagaaac aaaatcttaa aaattaccat ggtctggcgg atctctcggg 6301 aagtgcgtag gatcagctgg ggaaggtcct ggcatactgc gcatttcctg atcgaaagga 6361 tcccgtgacc gagcatagaa gaaaaagcaa agctgcgttg gtcgaaaatt cacactgact 6421 tttctttcca cacaaaagcg aagaaaacgt tcgaaatgga attagctttt taatttttaa 6481 gttacagtta ttctgcttct aattgtaaat cttgtgcaat gtaaacaatc agaatttttc 6541 tttgaatata aaacaatacg aacacaccga aaccaagagc aaacaaacgc gtatcggtca 6601 cagtgaaaat gcaaaatgaa aacatataag atttcaaaaa taaataatgg aaatatgatt 6661 agcaactaaa cgatgtcatt caatttagac taggctacac acaaaaacca taaattgtta 6721 agactctatc caaagagcta agaaacgcga actcaaacaa aacatactag aaatagatat 6781 ttacaagcaa caataagtat aattcgaata tcgaacagaa cgaagaaata gttaagcata 6841 tatgaatatc gagcaaattg gtttttatgc gattcggtta gaggaaattt tcaaacatca 6901 ctttgtatgc agattttgta tgcccaacta tacagatttc tgatccgctc tttttttttt 6961 tttgcttgat ttaactttaa atgattgatc gaaatttaca gataaggttt agcttttgat 7021 aaaaaaaaga ttgcaaatgt aaaataatat gagaacttgg tatattttga tgaaaggtga 7081 aattatttgt acattttgtt gtatgcccac gggattagct ggaaacggtt gatatttgtg 7141 ggggactttc ttaatgtttt tgataaacat gtattttatt ttatatgctt ttccaatgcg 7201 attgtcagtg agaacgatta acgatagatt tcaatcctaa cgcttaagag tattaatgaa 7261 ataataatag agaacatagc aaacaagctg ccagcatgaa aaataaaaac aataactaat 7321 tttaaatctt ttatacattt ccatcaaatg tgcttattta aacacaagag aatgcaaacc 7381 aaaatgccca actgaaatat ctgatggccg ttttcaaata gcaatcaata actggattat 7441 gttcaacatc caattagctg aagttgaaca aatgttttca tataagcaat ttttaaagaa 7501 aaacgtcacc ccggtaaata aatacatagg aaatagtaag gcaatctggg ctgactgact 7561 aatcgtcaaa attagtcgag gccatcgaat ggagcagaat gacggagatt aaaactaata 7621 aagttctaga gcataatgag gacagtttgg aaaatagttc ttgatcaacc attaatacac 7681 agtttataca tatatgtgta tatttacatg gatatatatg tatgtgcgta cgtatatact 7741 tctttttaca cagac //