Dbfetch
LOCUS NM_001258591 9545 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster twenty-four (tyf), transcript variant K, mRNA. ACCESSION NM_001258591 VERSION NM_001258591.2 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 9545) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 9545) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 9545) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 9545) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 9545) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 9545) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 9545) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 9545) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 9545) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 9545) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 9545) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 9545) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 9545) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 9545) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 9545) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 9545) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 9545) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 9545) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 9545) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 9545) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 9545) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 9545) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 9545) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Oct 19, 2015 this sequence version replaced NM_001258591.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..9545 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..9545 /gene="tyf" /locus_tag="Dmel_CG4857" /gene_synonym="CG485; CG4857; Dmel\CG4857; EG:EG0007.12; EG:EG0007.4; TYF" /note="twenty-four" /map="4B1-4B1" /db_xref="FLYBASE:FBgn0026083" /db_xref="GeneID:31363" CDS 520..5523 /gene="tyf" /locus_tag="Dmel_CG4857" /gene_synonym="CG485; CG4857; Dmel\CG4857; EG:EG0007.12; EG:EG0007.4; TYF" /note="CG4857 gene product from transcript CG4857-RK; CG4857-PK; tyf-PK; twenty four; TWENTY-FOUR" /codon_start=1 /product="twenty-four, isoform K" /protein_id="NP_001245520.1" /db_xref="FLYBASE:FBpp0293713" /db_xref="GeneID:31363" /db_xref="FLYBASE:FBgn0026083" /translation="MLKKAEYDEEISYRAIKSCLTINPSALTSSAATGSSGGSSSSAG HNSSYNSTNHRSTDPGQRHKQGGSLQDLVEAAHRSELATTSAAAAAAATAAATQRFNC DYQLSGRSNRRQQQQQQQHNQNATSSASASKKIKNLNVSGRQREGGSLPSSVNFEPAS SAMEAKQNKQQAQPSTEAAGGSFSGSVGNKHHHRSSTGSCSSLITQSRDTEANNQFDL DMDDATGVGASAVVGASGDQDDNMLEQLDPQNPSMKFLIDALNDTPLEARYTGAGKKF LIDDRLHFSVLELSARRKLQQQAQYLAALTGQFGLGLEEEKRKVEAGYVSLNDNYTAC SSVYGGGAGSPAAVEGSKPSTSSSAVSGGSNCGASSDALSSDLRPAKIGRMVPAAAAV AAAPMGGKTTTRQLDENGNALGDGFGGSAASGSSGASGASAAASSSNGNGNANQFTAL ITPTVGSSVPTSTVAHRQNSVSTLLSTGTNTTTTAMAAAAVAASYSQLQQAPVGGAAG TVSGIGIGMQQPTKQKTKKKSQQERNTTTVDVESVAGYRGNDPVEQLVKYIENDVNGG GNSAAGQRKKERKKQNKLKKSNSLEELRTCSKMEVDDLKRQSATTEMMRHKKGTNNAS SGGSSSTASGSSNSGKHNSASVADINKNCNKEQQQQSTPTVQVRNSNNPGTQQRKGER RSWGTEELQYLGDHQEISAAWSELETVGQKELPLALPALARMSELDALNTVLSETAEF HVVTKKKKPKKQRAVTMDDAAVAAAAVTGGNLQRMQQITKSASSNIMSQRMHYYTPYN SNNGGGSVNYKQQQQQSQQYQEHYQAPQGQHHHHHHHHHHHHHHHSGSAVSNQVDSSR RKSTSSMPPSEKSDSSDLDSVHSLPIQTGKKKSLGGGNNKQRGAPSASQRQAKQNNNA AAPISYADIARNKQEALNNATASDTELELGDKMQIKSGGKSKSRPDFPELPGAVTAVA ASGGAANQATVVSSQNTPPSSSSSISYSQSLNATPPSSSSDAESTNSPELLAQVQIPA YSMITPTLTASMISSVSSSVASTSSTSCSPPALQKSKSVEHDTSYSCNSSNLDQQYPA LEKTVKRHSTNNVSVAVAASTSASASSSLYNFAAAAKQQLTENTHSAVSPPAAVTTTS TAVAASAPAPTTVTVPAAVTVPCYSSSSTHGSTQTSTSTASSAIAALPSGKAKAKPKE LSPSSSCSKKPTKPSQDVPSISLSISTTPRATTSTSTTTTQKTTAATQTEGAKKLIGG IHKLPSSSCIAKGAGAVLEATAGRRAVIILNDDREAGRSNNEFIFGDFNEDELKLFDD NLDDEEEGQHKQSSNKKQQTEGESDVTQDDTEDVDQDLDKELECLGRRPEKKQERQQD ISASSDQHLNDSGAASDAVNSSASLDMLSISAEAAQSSPNAGATATSSSVASPINSST PSGASSASASTSTSSSSVSISSSSGGNGAACLASVSGMLGGVANQSGDSGIYAAANTS IKEHVNTFLSKASSSEETLPSPNSISMQQLETCNDIEAAIIAAARAAAAARSTSCSRS NSQEQDALQPQVKTKATPNPEAKMVLPVFVTYNNNNNDDDDDEEDDESLQELSFMADL KADAATEDIAMQPPPPSCPAMMTNTELIVDYIAKTWNAIANSKYVTYYNEQEQEQET" ORIGIN 1 ctgactgact gggattgtgg ctttcgaaat agtgccgtta catttggtcc catcaagtaa 61 tcgccacaca ggaacttcaa tttctgatcg cagtcggttt tttgaccagc gccttcgata 121 attattgaaa tcaagacccc gaatcgggca gaaggaacgg ataaaaccgc aaagcgtttg 181 tttatcttat aaaagcattg gtgacatccg cggcattaac cacgaaaact tctcgcctat 241 tcccgttatt atttcagtta ttgttttttt tttttttttc tgttttcttg tgttcgtgtg 301 caacaccata tagtacacat gtgtgtgcgt atgtagagcg tttacttact ggaaccgtgt 361 gccatttaat acttctattg ctctgcgaca aaatacgata cctgggaaga tagcgatttt 421 aatgatctgg acgacgcatc attgaagaaa cttctcgaag aggcctactg gtatcgaaat 481 cctggcgaca ggaagaacaa gagcgagcga tttctgcaaa tgctcaaaaa ggctgagtac 541 gacgaagaga tctcttatcg tgccatcaaa tcctgcctca caatcaaccc atccgcacta 601 acgtccagtg cagcaacagg ctcgagcggc gggagcagca gcagtgcagg gcacaacagc 661 agctataatt ccaccaatca ccggtcaacg gatcccggcc agcggcacaa gcagggcggc 721 tccctgcagg atctcgttga ggcggcgcac cgcagcgaac tggccacaac ctcggcggcg 781 gcggcagcag cagcgacagc ggcagcaacc caacgtttca actgtgatta ccagctgagt 841 ggtcgctcca atcgccggca gcagcagcag caacagcagc acaaccaaaa cgccacctcc 901 tccgcatccg catccaaaaa gatcaagaac ttaaacgtct cgggccggca gcgcgaagga 961 ggcagcctgc ccagcagtgt taactttgag ccggcatcgt ctgccatgga agccaagcag 1021 aataagcaac aggctcagcc ttcgacagaa gctgcaggtg gctcgttttc ggggtcggtc 1081 ggtaacaagc accaccaccg cagcagcacc ggcagttgca gcagcctgat aactcaatcg 1141 cgcgatacgg aggcaaacaa tcagttcgac ttggacatgg acgatgcgac gggtgttggt 1201 gccagcgccg ttgtcggtgc cagcggcgac caagacgaca acatgttgga gcaattggat 1261 cctcagaacc cctcgatgaa gtttctgatt gacgccctaa acgacacgcc attggaggcc 1321 aggtacaccg gtgccggcaa aaagttccta atcgacgacc ggttgcattt ttccgtcctg 1381 gagctgtctg ccaggaggaa gctgcagcag caggcacaat acctggccgc cctcaccgga 1441 caatttggtc tcggcctgga ggaggagaag cgcaaggtag aggccggcta cgtgtcgctc 1501 aacgacaact acacggcgtg ctcctcagtt tacggcggcg gtgcaggttc gccagctgcc 1561 gtggagggca gcaagccctc tacctcctcc tcggccgtgt ctggcggtag caactgcggt 1621 gcctcctctg acgcactgtc tagcgatctg cgacctgcga agattggacg catggtcccc 1681 gccgcagcgg cagtggcagc tgcgccaatg ggtggcaaga cgactactcg acagctagac 1741 gagaatggaa atgcattggg cgatggtttc gggggcagtg cagccagtgg ctccagtggc 1801 gccagtggcg ccagtgctgc cgccagcagt agcaacggca acggtaacgc aaaccagttc 1861 acagctctaa taacccccac ggtgggatcc agtgtaccca cctctactgt cgctcaccgt 1921 cagaatagtg tctccacgct gctctccacg ggcaccaaca ctacaacaac ggccatggca 1981 gcggcggcgg tggctgcatc ctacagccag ttgcaacagg caccggtcgg aggcgcggct 2041 ggaacggttt ctgggatcgg cattggcatg cagcagccca ccaagcagaa gacgaagaag 2101 aagtcgcagc aggagcgcaa caccaccacc gtcgatgtgg agtcggttgc cggctatagg 2161 ggcaatgatc ctgttgagca gctcgtcaag tacattgaaa acgatgtcaa cggtggcgga 2221 aacagtgccg ctggacagcg caagaaggag cgcaagaagc aaaacaagct caagaagagc 2281 aactcgttgg aggagctgcg cacctgctca aaaatggagg tggacgattt gaagcgccag 2341 tcggcgacca cggagatgat gcgacataag aagggcacga acaatgcatc ctcgggcgga 2401 tcgtcgtcga cggcctctgg ttcctcaaac agtggcaagc acaactcggc atccgtggcg 2461 gatattaaca aaaactgcaa caaggagcag caacagcaat cgacgccgac ggtgcaagtg 2521 cgcaacagca acaatccagg aacgcagcag cggaagggcg agcgtcggtc ctggggcacc 2581 gaggagttgc agtacctggg tgaccaccag gaaatatccg ctgcctggtc ggagctggag 2641 actgtgggcc agaaggagct gccgctggcg ctgcccgcct tggcgcgcat gtccgaactg 2701 gatgccctga ataccgtctt gtcggagacc gctgagttcc atgtggttac caagaagaag 2761 aaaccaaaga agcagcgtgc tgttaccatg gacgatgcgg cggtggctgc agctgccgtc 2821 acgggcggca acttacagcg catgcagcag atcaccaagt ccgcgtcctc caacatcatg 2881 tcccagcgga tgcactacta tactccgtac aacagcaaca atggtggagg cagtgtcaac 2941 tataagcaac agcagcaaca gagccaacag taccaggagc actaccaggc gccacagggg 3001 cagcaccacc atcaccacca tcatcatcac caccatcatc accatcacag cggctcggcg 3061 gtttcgaatc aggtggatag ctcacggcgc aagtccacgt cgtctatgcc cccatcggag 3121 aaatctgact ccagtgatct cgactcggtc cactccctgc ccatccagac ggggaagaag 3181 aagagcctag gcggtggcaa caacaaacaa cggggggcgc cgtcagccag tcaacgccag 3241 gccaagcaaa acaacaatgc tgcagccccc atttcgtatg cggatatcgc ccggaacaag 3301 caggaggctc taaacaatgc cacggccagc gacaccgagt tggagctggg cgacaagatg 3361 cagatcaaga gtggcggcaa atccaagtcg cgacccgatt tcccggagct gccaggtgct 3421 gttacggcag tggctgccag tggaggtgca gccaatcagg cgacggttgt cagcagccaa 3481 aatacgccac catcctcgtc cagttccatc agttattcgc agagtctcaa tgcaacgccg 3541 cccagcagca gcagcgatgc ggagtccacc aactcgccgg agctgctggc gcaggtgcag 3601 ataccggctt acagcatgat cacgccaact ctaacagcct ccatgatcag cagtgtcagc 3661 agttctgtcg ccagcacctc ttccacatcc tgctcaccgc cagctctgca gaaatccaag 3721 agcgtggagc acgacaccag ctacagctgc aatagtagca acttggatca acagtatccg 3781 gcactagaaa agaccgtcaa gcggcatagc accaacaacg tgtctgtggc cgtcgcagcc 3841 tccacctcgg catcggcgtc ctcctcgttg tacaactttg cagcggcagc caagcagcag 3901 ctgacagaga acacccattc ggccgtatcg ccgccggcag ctgtaacaac tacctcaacc 3961 gcagtcgcag cctcagctcc agctccaact acagttacag ttccagctgc agttacagtt 4021 ccttgttatt cctcatcctc cacacacggc tcgactcaaa cttcaacttc tactgcatcg 4081 tctgctatag cagctttacc ctcgggcaag gccaaggcca agccaaagga gctatctccc 4141 agcagcagtt gcagcaagaa gccaacgaag cctagtcaag atgtgccgtc aatcagtctg 4201 tccatttcca ccacgccaag ggcgacgacc agcaccagca ctactactac acaaaagacc 4261 acggctgcca cgcagaccga gggagccaaa aagctaatcg gcgggatcca caagctgccc 4321 agtagcagtt gtattgcgaa gggagccgga gccgttttgg aggccaccgc cggcaggcgt 4381 gctgttatca tactcaacga tgatcgcgaa gcaggcagga gcaacaatga gttcatattc 4441 ggtgatttca acgaggatga gctaaaactc ttcgacgaca acttggatga tgaggaggag 4501 ggccagcaca agcagtcttc aaacaagaaa cagcaaactg aaggggaatc tgatgtgacc 4561 caagatgaca ccgaagacgt ggaccaagat ctggacaagg aactggaatg cctgggacga 4621 cgaccagaga agaagcaaga gcgacagcag gatatcagcg ccagcagcga tcagcatctg 4681 aatgattctg gtgcggcttc ggatgcagtc aacagctcag ccagccttga catgctctca 4741 atttctgcag aggcggcaca atcgtcacct aatgcggggg caaccgctac ctcatccagc 4801 gtcgccagtc ccattaactc gtccacgccc tcgggtgctt cgtccgcatc ggcgagcacg 4861 tccacctcat cgtcctcggt ctcgatttca tcatcgtcgg gcggcaacgg tgccgcttgt 4921 cttgcatccg tttccggtat gcttggtgga gtggccaatc agtccgggga cagcggcatc 4981 tatgctgccg ccaacacgtc tattaaggag cacgttaaca ctttcctaag caaggccagc 5041 agcagcgagg agacgctgcc gagtcccaac tccatatcga tgcaacagct ggaaacatgc 5101 aacgacatcg aggcggccat catagccgca gcccgtgctg ccgctgctgc ccggagcacc 5161 agctgcagtc gcagcaactc tcaggagcag gatgccttgc agccgcaggt caagaccaag 5221 gcgactccca atccggaggc gaagatggtt ctgcctgtgt ttgtgaccta caacaacaac 5281 aacaacgacg acgatgacga cgaggaggac gacgagagcc tgcaagaact gagcttcatg 5341 gccgacctta aggcggatgc agccacggag gatattgcaa tgcagccgcc accgccttca 5401 tgtccggcga tgatgaccaa cacggaacta atcgtcgact acatcgccaa aacctggaat 5461 gccattgcca acagtaagta cgtaacgtac tacaacgagc aagagcagga gcaggagacc 5521 tagaaaccac acaaacagca atcgctgcag cgtcagcgaa atcgaaatca gcaacatcgg 5581 cgtcaatcac aatagcaacg tcagcaatat cggcagcaat ctaacgagag catccaacgt 5641 cggctgaaat caggagagca gattggttgg aatagagtgt tctaaaagtt aaaatttttt 5701 ttttttttgc tgggctattg tttatatatc taccgatatc gtacacacac tatatattat 5761 tgcaataatg atacgcttta atgctaatta atgtaacgag tcgatagccg aactattgat 5821 taacttttgc aagcgcggca gccgaggatc agggtagaca tctaacccat ggggtcaccg 5881 ttgtcaagaa gtatcttcag gtgtttccag tgtgagtgca ggagtacagg atcgtgtcgg 5941 ctagggttcc ggtgccgcat gcctaatagg ttaactgttg cagaaagaaa attttataga 6001 gaaggagagc gttcagctgt gaataagaag gaaatcataa ctaaatgaag tgatcttacg 6061 aaagcttcaa gtgaatattt atttaacata agttgaccga gatttaaacg tttttttttt 6121 tttcgcctca agaagcgatg gtcagatagt gatgttcaat caagcatttg gatctgcttt 6181 tgttaattta caaccttctg gatcccgaaa acgcaacgtt ttaccattac tattactatt 6241 attgtacttt aataattatt atgcaaacgt tttttcgtca ttgtttcata tgcccaattt 6301 ttgggcgcgt tgtttggagg aaatcctaat cctagatatt aaaccgagtc aacgtcgcgt 6361 gtacatagtg gaccagaagt cgtgtgggca gttcgatctc tgtgttatgg attagtggaa 6421 acagaacaaa tcagaacagg atagaacaga gcaaaacaga aagccccacg gaagatattt 6481 gatatgtgtg tatgataacg actatttaaa gtaaactatg taaggccgct tctttgctcc 6541 ggctagccat aaataagcct caagaggaga gtatgttaaa ccgaataacc gaatgcaaac 6601 agagaaccac aaaataccgg caaaaacact attatgcact tacgaaaaat gccgccgttt 6661 agctgggaga gcctcagatg gtctctccga gggtatagaa gtatagatat cgtaactatt 6721 taaacaagaa ttaatttaaa agtaacaaac acgaaaaagt tcggcagtga agaaatgaat 6781 tggagtcaaa ggcggatacg gagaaacaaa caaacaataa gcgttaagta aactcgtaag 6841 tataaagagc gcaactaaat tgctatcaat aggaatatac attatatacg tgcatctatt 6901 aacgtaactt tttttttttt aaatgcaaac gttaaccgtt taaaatcgag tatgtaacag 6961 caggtagcag ttaggtgaac aaaagtcgga ataaaattac ggaaataaat cattaattta 7021 aagtatctaa agtgcgaatc gagaaagcct atttaaagct aatcattaaa acatttaaaa 7081 gtcccatttg gaatgcccag aggaagtggg catgtccgaa taaacagaac aaacagtgcg 7141 aaatgttttt tagatatatg tgaaactgtt ttgcttcaat cgctgtatat tttgaaaata 7201 aaagttaagt aatatgccgt aaagcgggac atgtattcaa caccactcaa caccccgagt 7261 cctgaccctt gaaccttgac ccttgaccct ctaaaactcc gcatgcaaca ctcggccaga 7321 gctgttgctg tgctgctcta aaccatgtta gccatccgca gcagaatcaa aagtcagagc 7381 aggagaattt taactgagtt gctaggagga cgataatatg gaatatatga aatatttgta 7441 tctgtaccac acacattaag caaacattaa ggaaacacac actagtttac aaatttggcc 7501 ttttggcggt taccttaagg agcgttatat tttctaatta aaattctaaa gcgaatgagt 7561 gtatccgaac ccagctaact gtaggtttat catacgaata ttaataccaa cctgcgaatg 7621 gaataaacct gtcaaaatat tgtttagtga attgtatttc aaacaaatta tttaaatact 7681 acgtgtttta tagtcgactg gttattatac ccgttactcg tagagtaaaa gggtatacta 7741 gatacattga aaagtatgta acaggcagaa ggaagacttt ccgaccatat aaagtatata 7801 tatattcttg atcagcatca atagccacgt ccgtctgtcc gtatgaacgt cgagatctca 7861 ggaactataa aaggtagatg gttgagattc agcataaaga ttctagagac atagacgcag 7921 tataagtttg ttgacccatg ttgccacgcc cactctaacg cccacaaacc gcacaaaaat 7981 gtcacgccca cacttttgaa gaatttttaa atgaaaaatg ataaaatttc gcgttcgcat 8041 tcacattagc tgagtaacgg gtatgtgata gttggggaac tcgactatag cattccctct 8101 tgtttttcgc cagtaaacat tacttccttt tacatccaac gctcttttcg aaaatatcaa 8161 aacagttttt ccgttctatt tagaaaacac atgtttaatt tcagcaaact caaattagtc 8221 taagaaacgt gttttaaaga cgtacatctt tcgtgtaaac tagtgttata tatgtacaac 8281 cactaagtca aactaagcca atgtacactg caacaatttt agacaattga gaactaacga 8341 gaaacagaaa caagatacac aaaaccgaat atataagggt atggaaaaga acatgaaatt 8401 aaattatacg ataggccagt aattaaacat aatactgaaa tattattaat tacttataaa 8461 caaacggaaa aaacacaaaa aaaaaagttt cttatgtgtg tatttatgta atatatatat 8521 tgtagttgtg tgtatgtgta tataaatagt aaattgcgac tcgagacaaa gaaaatcaca 8581 gaggcatacg aagaaggatc agtcaagata atcggacatt cattttcccc gcttatagta 8641 aaccgccttt ttcgtaggac gagggtggct cgagcttgga gtttgaaggt cgagacatcg 8701 gccgacagac caaaactagg atcgtttgtt ttagtttggc cttttgtttt tacgtagcta 8761 gcgtattgtt caatttatcg gatattagat atcggagtaa tcgctcgagt tgcgtacagt 8821 tcagtctgca ttatttccgt cttgcgtgca cttgttgagt ttgaaataca aaataacaat 8881 aattgggaac ggagtggagt ggcgagaatt gaagcagcag agagcacagt gggaactata 8941 atcatagata tacatacatg taacaaagtc tacgactaag tctatttact actgatgaac 9001 ctactaagta acccccaatt cccgatcccc caaaattcca acccatccct atatataact 9061 tatacatacc aatatttgta catgcgaaac aagcgaaagg ctttagaatt taatcgtaat 9121 ggtccgaaaa tcgattaacc aatcgaagca gaagcagcaa ctgaatggga aaccgaaatt 9181 taatttataa tttgtttaaa ttatcatata ctggagagaa gtgtatttct gtggagaatc 9241 gaaataaaat ttaacaaaaa aaaaaaaaga aaacagctgc attcgattta caatgaattt 9301 cgagggttgg gtacacatag gatattgcag gtttaagtat tgatgaatgg agctgatggt 9361 gtaaactaag gtaccagatt tcctgcatca gatctatccc ttgggcaccg gcagaaggca 9421 actggaggac atcatcgagc ggaaatgcga ccggcgtgtt agaaattaag ctattattat 9481 tattagtttt ctattattat taagacatag gatattattt atacaatata agtgaataaa 9541 atatt //