Dbfetch
LOCUS NM_001258556 9407 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster enhanced adult sensory threshold (east), transcript variant F, mRNA. ACCESSION NM_001258556 VERSION NM_001258556.2 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 9407) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 9407) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 9407) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 9407) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 9407) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 9407) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 9407) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 9407) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 9407) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 9407) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 9407) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 9407) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 9407) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 9407) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 9407) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 9407) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 9407) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 9407) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 9407) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 9407) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 9407) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 9407) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 9407) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jul 15, 2014 this sequence version replaced NM_001258556.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..9407 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..9407 /gene="east" /locus_tag="Dmel_CG4399" /gene_synonym="anon-WO03040301.224; CG4399; Dmel\CG4399; East; EAST; EG:133E12.4; l(1)G0014; l(1)G0500; su(w[sp])" /note="enhanced adult sensory threshold" /map="2C2-2C4" /db_xref="FLYBASE:FBgn0261954" /db_xref="GeneID:46006" CDS 196..7224 /gene="east" /locus_tag="Dmel_CG4399" /gene_synonym="anon-WO03040301.224; CG4399; Dmel\CG4399; East; EAST; EG:133E12.4; l(1)G0014; l(1)G0500; su(w[sp])" /note="CG4399 gene product from transcript CG4399-RF; CG4399-PF; east-PF; enhanced adult salt tolerance; suppressor of white-spotted" /codon_start=1 /product="enhanced adult sensory threshold, isoform F" /protein_id="NP_001245485.1" /db_xref="FLYBASE:FBpp0298291" /db_xref="GeneID:46006" /db_xref="FLYBASE:FBgn0261954" /translation="MSSRKVPGGSGGADESTAAAAPLDDNANASVEIPDSSEEPAMGV GEEMSIISKTRTSTLSVEPAKEPTVTAELEGEKELESNPVSKTPRSTPTPTLTPAVTP TASDGVAAKSVRVTRHSSPLLLIISPTTSRREVGDGELDTEEPTGSGGQRKSSVERSL APVIRGRKSIKDLKEAKEVKSEEPPAAASESRAASGVTPGQVKEQHVADGNEMESLPI TDKKDHKDTKDKGDERETDQEEEKEKSADTEIIADTEKTSEKQKYTEKDKAADKDGGK EKDIDANKDIDKEKEKVKEVLPPVVPIAPVTPTCNRVTRKSHAQEQAINTRVTRNRRQ SSTVGANSTASLVAASSSVTEQPPPSRGRRKKPVVVAPPLEPAVKRKRSQDVEADSDA NNSTKYSKVEVVKSEEAEAPEEDSSAVPIKQESVDGNEVSSISPTVTPTPTPAPTPAP VPGSRRGRGRPQNRNSSSPATTTRATRLSKAGSPVILTPVAQEPAPPKRRRVGSSTRK TVSASSLAPSSQGGAGDEDSKDSMASSMDDLLMAAADIKQEKLTPDFDDSLMPEGLPS TSGASSANGHSCTEPLTVDTEINVKPADSKVKPKESPVVAVEESPSQSETQSAKVSAH AGKAPSLSPDMISEGVSAVSVRKFYKKPEFLENNLGIEKDPELGEIVQTVSNNDTETD VEMAVDGEVNQPSTPKSQDKKKEEQEKNQKSGLKAAKKAPAKLEPKAEDISEILTDVP VDISTEAVEIIEEAEEDTCSNSSIKPGELRLDESNDEPELLLEDALIVNGDENETPDQ PEEKEDQVEFFHTGEYDDFEHEIMVELAKEGVLDASGNALSQQKVELEHPEDVTLHES KNDIEAEESVERKPLKDPSVADEMEDMNEESYIDIKDQTNQLLVEHLAEEAMEADCGP EDNKENLSTSASSTAADGLDIQLAIKEDDDEEKPLAVIADEQKPGLLLTNDMKVDEKP NGKQESVCDEHVQLVPNLRQEQEIHLQNLGLLTHQAAEHRRKCLLEAQARQAQMQLQQ HHHHQHKRQGARGGGSATHVESSGTLKTVIKLNRSSNGGVSGSGGLPTGTVIHGGCGS SSASSTSSSSVGSATRKSSGTLGSGAGAGAGVRRQSLKMTFQKGRARGHGAADRSADQ YGAHAEDSYYTIQNENEGAKKFVVTTGNTGRKTNNRFSSTNNYHSTVALHGSNSALQY YSSHSESQGQTDHGFYQMVKKDEKEKILIPEKASSFKFHPGRLCEDQCYYCSGKFGLY DTPCHVGQIKSVERQQKILANEEKLTVDNCLCDACFRHVDRRANVPSYKKRLSASGHL EMGSAAGSALEKQFAGDSGVITESGGEAGSTAAVAVQQRSCGVKDCVEAARHSLRRKC IRKRVKKYQLSLEIPAGSSNVGLCEAHYNTVIQFSGCVLCKRRLGKNHMYNITTQDTI RLEKALSEMGIPVQLGMGTAVCKLCRYFANLLIKPPDSTKAQKAEFVKNYRKRLLKVH NLQDGSHELSEADEEEAPNATETERPTSDGHEDPEMPMVADYDGPTDSNSSSSSTAAL DTSKQMSKLQAILQQNVGADAAGAAGTGTVAASPGGSGSGADISNVLRGNPNISMREL FHGEEELGVQFKVPFGCSSSQRTPEGWTRVQTFLQYDEPTRRLWEELQKPYGNQSSFL RHLILLEKYYRNGDLVLAPHASSNATVYTETVRQRLNSFDHGHCGGLNIAGSPSSSGS GKRSGVPQPTGASVLATALTTPLTSHSSSSASISSEQHSSVDPVIPLVDLNDDDEGED GAGGAGERESTNRQQDVILECLRTASVDKLTKQLSSNAVTIIARPKDKSQLSCNSGSS TSISSSSSAISSPEEVAVTKVTAVAPVQSKDAPPLAPASSGVSNSRSILKTNLLGMNK AVELVPLTTAPHAYKPTGCHKPEKQQKILDVANKQPGSQGEPVPSSALLGLQSKLKPP THQQQVSGSGAGTSGSQKPSNVAQLLSSPPELISLHRRQTSGAAAGSSSFLQGKRLQL PRSGAGPSGAGTGTGAGAAGSRSAGGPPPPNVVILPDALTPQERHESKSWKPTLIPLE DQHKVPNKSHALYQTADGRRLPALVQVQSGGKPYLISIFDYNRMCILRREKLMRDQLL KSNAKPKPQNQQQQQGQTHQQQQNSAASAAAFSNMVKLAQQHTARQQLQQLQQKPQQQ QQLPTLQPGGVRLARLPQKLLMPPLTNPQIGSQAPNLQPLLSSTLDNSNNCWLWKNFP DPNQYLLNGNGGGAGSSSSKLPHLTAKPATATSSSGAANKSAGSLFTLKQQQHQQKLI DNAIMSKIPKSLTVIPQQMGGNTGGDMGGSSSSGKD" ORIGIN 1 tgctcgctac tgcctatatt cttcacatca cagtcaacca atgggaccaa atcactgcga 61 ctcgaactgg acacaatcag catcggatcg cagggaacaa caggaggtgg tggagcagca 121 gcgccagaag gcgtcggggg agcggccatc ataggagcag caacgtcggc agcagctgcc 181 cagggcccct cgagaatgtc tagccggaag gtgccaggag gctctggagg agctgacgaa 241 tccacagcag cagctgcccc cctggatgat aatgccaatg ccagtgtgga gattccagac 301 agcagcgagg agccagcaat gggcgtcggc gaagagatgt ctatcataag caaaacacgc 361 acctcaactt tgtcagtgga gcccgctaag gagccaacag taacagcaga gctggaaggc 421 gaaaaagagc tggaatcgaa tccagtctcc aaaactccta ggtccacgcc tacgccaacc 481 cttacgccag ccgtcacgcc taccgccagt gatggagtgg cggccaagag cgtgagggtt 541 acccggcact cgtcgccact gcttctgatc atctcgccca cgacaagtag acgtgaggtc 601 ggcgacggag agctagacac cgaggaacca acgggatcgg gtggccaaag aaagagctcc 661 gtggagcgat ctttggcgcc cgttatacgc ggacgaaagt ccatcaagga tctgaaagaa 721 gccaaagaag tcaagtccga ggagccgcct gccgcagcat cagagtcacg agctgcaagt 781 ggagtgacgc ctggccaggt caaggaacag catgtcgcgg atggcaacga aatggaatcc 841 ttgccaatca cagacaagaa agaccacaaa gacacaaaag acaagggaga tgagcgggaa 901 accgatcagg aggaagagaa ggaaaaatca gctgatacag aaataattgc agatacagaa 961 aaaacttcgg agaaacaaaa gtatacagag aaggacaaag ctgccgataa agatggagga 1021 aaagaaaaag atattgatgc aaataaggat atagataagg agaaggaaaa ggtcaaggaa 1081 gtacttccgc cagtggtgcc tatagcacca gtgacaccca cttgtaaccg tgtcacacgt 1141 aaatcacatg cccaggagca ggcgattaac acgcgggtca ctcgcaatcg tcgccagtcc 1201 tctacagttg gagccaactc caccgcgtct ttggtagctg catcctcctc agtaacagag 1261 caaccccctc catctcgcgg tcgacggaag aagccagtgg tggtggctcc tcccttggag 1321 cctgcggtaa aacggaagcg atcgcaagat gttgaagccg actcagacgc caacaacagc 1381 acgaaataca gcaaggtgga agtggtaaag tctgaggaag ctgaggcacc agaggaggac 1441 tccagtgccg tgcccattaa gcaggaatct gttgatggca acgaggtcag ttctatttct 1501 ccaacagtca cgcccacacc cacacctgcg ccaacaccag ctccagtccc gggcagtcga 1561 cggggtcgtg ggcgcccgca gaacaggaac tcctcttcgc ctgcaaccac aacgcgggca 1621 acgcggctaa gcaaggcggg atcaccggtt atcctgacgc cagtagccca ggaaccggcg 1681 ccaccgaaac ggcggcgagt cggctccagc acacggaaga ctgtctcggc cagctcgctg 1741 gcacccagct cgcagggcgg cgccggggat gaggactcca aggacagtat ggcctcgtcc 1801 atggacgacc tgctgatggc cgcagcagat atcaagcagg agaagctgac gcccgatttc 1861 gacgatagtt tgatgccaga aggcctgccc tctacttctg gtgcgtcgag tgccaatggt 1921 cattcctgca ccgaaccgct tactgtggac acggaaatta atgttaagcc cgctgattcc 1981 aaagtaaaac caaaggagtc accggtggta gcagtcgagg aatctccatc acaatccgaa 2041 acgcaatctg caaaggtgtc agcgcatgcg gggaaggctc catctcttag tccagatatg 2101 ataagtgaag gcgtgagcgc ggtcagtgtt cgaaagtttt ataagaagcc tgagttcctg 2161 gaaaacaatc tgggcattga aaaggatccg gagctaggtg aaatcgttca gacggttagt 2221 aacaatgaca cggaaacaga tgtggagatg gctgttgatg gcgaggtgaa tcaaccgtca 2281 actcccaagt cgcaggataa aaagaaagag gagcaggaaa agaatcagaa atcagggcta 2341 aaggcagcaa agaaggctcc tgctaagtta gaacctaaag ctgaagacat ttctgaaatt 2401 cttactgacg ttcctgttga tatttcgact gaggcagtag aaattataga agaagcagag 2461 gaagacactt gttcaaatag ctcaatcaaa ccaggtgagc tccgactgga cgagagcaac 2521 gatgaacctg aactgcttct tgaagacgcc ctcatagtca atggtgatga gaatgagaca 2581 ccagatcaac cggaggaaaa ggaggaccag gtggagttct tccatacagg agaatacgac 2641 gactttgagc acgagattat ggtggagctg gcgaaggagg gggtgctaga tgccagcggc 2701 aatgcattaa gtcagcaaaa ggtagaactt gagcatcccg aggatgtaac tctacacgaa 2761 tcaaaaaatg acatagaagc cgaagaatcg gttgaacgta agcctcttaa ggacccgtcg 2821 gttgcggacg aaatggagga catgaatgag gaatcctata ttgacattaa ggaccagaca 2881 aatcaactgt tagttgaaca cttggcagaa gaggccatgg aagcggactg cggtcccgag 2941 gataacaagg agaacttgtc cacgtctgct tcgagcaccg ctgccgatgg tctagatatt 3001 cagttggcca tcaaggagga tgacgacgag gagaaaccgc ttgcagttat cgctgacgaa 3061 cagaagcctg ggctgctgtt gaccaatgac atgaaagtgg atgagaaacc aaatggcaag 3121 caggaatcgg tctgtgatga gcacgttcag ctggtgccaa accttcgtca agaacaggaa 3181 attcacttac aaaatctggg cctactcacg caccaggccg ctgaacatag gcgcaagtgt 3241 ctgcttgagg cacaggcccg ccaggcgcaa atgcagctcc agcaacatca ccaccatcag 3301 cacaagcgac aaggagcgcg cggaggaggc agtgccactc atgtggaatc cagcggtact 3361 ttgaagacag tcatcaagct gaacaggagc agcaacggag gagtaagcgg tagtggcggc 3421 ctgcctactg gtacagttat ccatggaggc tgtggctcct cttcagcttc ttccacgtcc 3481 tcctcctcgg tgggcagtgc cacacgtaag tcaagcggga ccttgggctc aggagcggga 3541 gcaggagctg gcgttcgccg gcagtcgctt aagatgacat tccagaaggg tcgggctcgt 3601 ggtcacggtg ctgcggatcg atccgccgat cagtatggcg cccacgccga ggactcctac 3661 tacaccattc aaaacgagaa cgaaggtgcg aaaaagtttg ttgtaactac tggtaatacc 3721 ggccgcaaga ctaataaccg tttcagctca actaacaact accactcgac ggtagccttg 3781 cacggtagca actctgcgct ccagtactat tcgtcccact cggaaagtca gggacagacg 3841 gaccacggct tctatcagat ggtcaaaaag gacgaaaagg agaagatcct cattccggaa 3901 aaggcctcct cgtttaagtt tcacccaggg agactgtgcg aagaccagtg ctactactgt 3961 agcggaaagt ttggcctcta tgacaccccc tgccatgttg gacaaataaa gtccgtggag 4021 cgccagcaga agatcctagc caacgaggag aagctcaccg tggataactg cttgtgcgac 4081 gcatgttttc gacacgtgga ccgccgggca aatgtgccat cctataagaa gcgtctttcc 4141 gcttcaggtc acttggagat ggggtctgca gcgggatctg cactagagaa acagtttgct 4201 ggcgacagcg gcgtcattac ggaatcgggt ggcgaagctg gttctacggc agctgtggcc 4261 gtgcagcaac gatcttgtgg cgtgaaggac tgcgtcgaag cggcacgaca ctcgctgcgg 4321 cgcaagtgca tacgcaagag agtaaagaag tatcagctca gcctggagat tcccgcaggc 4381 tcgtcgaacg tggggctgtg tgaggcacat tacaatacgg tcatccaatt ttccggctgc 4441 gttctttgca agcgtagatt aggcaagaac catatgtaca acataaccac gcaggacaca 4501 attcgactgg aaaaggcgct gtccgagatg ggcatcccag ttcagcttgg catgggcact 4561 gcagtctgca agctgtgtcg ctattttgcc aaccttttga taaagccacc ggatagcacc 4621 aaggcacaaa aggcggaatt cgtgaagaac tacagaaaga ggctcctcaa ggtgcataat 4681 ctgcaggatg gcagtcatga gctgtccgaa gcggatgaag aagaggcacc taatgcaacg 4741 gagacagaaa ggccaacctc agacggacac gaagatcccg agatgcccat ggtagcggac 4801 tatgatggac ctaccgactc caattccagt agttcttcga ctgcagccct ggacaccagc 4861 aaacaaatgt ccaagcttca ggccatcctg cagcaaaatg tgggagcgga tgcggcagga 4921 gctgcgggaa caggaactgt tgcagcaagt cccggaggaa gcggatctgg ggcagatatc 4981 tctaacgtat tgcgagggaa tccgaacatt tccatgcgcg aacttttcca cggcgaggaa 5041 gagctgggtg tgcagttcaa ggtgccgttc ggatgcagca gcagccagcg tactccggag 5101 ggctggacac gagtgcagac tttcctacaa tacgatgagc cgacgcgccg cctctgggag 5161 gagttgcaaa agccgtacgg aaatcagagc tcatttctgc gccacttgat actattagag 5221 aagtactacc gaaacggaga tctcgtccta gcaccgcatg cttcctccaa tgccacggtt 5281 tacacagaga ctgttcgtca gcggctgaat tcgtttgatc acggtcactg cggtggattg 5341 aacatcgcag gcagcccttc ttcttcgggt tccggcaagc gcagtggagt tcctcaacct 5401 acgggtgcca gtgtgctggc caccgccctc acaacaccct tgacaagcca ttcatcctcc 5461 tctgcatcca tttcctccga acagcattcg tcggttgatc ctgtcattcc gctggtagac 5521 ctcaatgatg acgatgaagg cgaagatggg gcaggaggag cgggcgaaag ggagtcgaca 5581 aataggcagc aggacgtaat cttggaatgc cttagaactg cctctgtgga caagctgact 5641 aagcagctca gctcgaatgc ggtgacgatt atcgcccggc ccaaagacaa atcgcagctc 5701 tcctgcaaca gcggatcctc cacgtccatt tccagctcct cgtccgctat ttcctcgccg 5761 gaggaagtgg ccgtcactaa ggttacagca gtcgcaccag tccagtccaa ggatgcaccg 5821 ccactggcgc cagcaagtag cggtgttagc aacagtcgta gtatccttaa aaccaacctc 5881 ttgggcatga acaaggccgt ggaactcgtg cccttaacga ctgcccccca cgcttacaag 5941 ccaactggat gccataagcc tgagaaacag caaaagattc ttgacgtggc caataagcag 6001 cccggtagcc agggggaacc ggtaccatca agcgccttgc ttggcctgca gtcaaagcta 6061 aagcctccaa cgcatcagca gcaggtcagc ggatcaggag cgggaactag tggttctcag 6121 aagccatcta atgtggcgca attgcttagc tctccaccgg agctaatcag cttgcatcga 6181 cggcagacca gcggagcagc agcggggtcc agcagcttcc ttcagggcaa gaggcttcaa 6241 cttccacgat ctggagcagg gccttcagga gcgggaacgg gaacaggcgc tggagcagca 6301 ggaagccgca gtgcgggtgg accaccaccg cccaatgtgg tcatactgcc ggacgcctta 6361 accccccagg agcgacacga gagcaagagc tggaagccaa cgctgatacc gctggaggat 6421 cagcacaagg tgccgaacaa atcacatgct ctttatcaga ccgccgacgg tcgaaggttg 6481 cccgccctgg tgcaagtgca gtctggtggc aagccatacc tcatctctat cttcgactat 6541 aaccgcatgt gcatcttgcg aagggaaaag ctgatgcggg accagttgct caagagtaac 6601 gccaagccaa agccgcagaa ccagcaacag cagcagggcc aaacgcacca gcagcagcag 6661 aattccgccg catcggcggc tgccttctcc aacatggtga agttggccca gcaacacacg 6721 gcgcgacagc agcttcagca gctgcaacag aagccacaac agcagcaaca attgcccact 6781 ttgcagccag gtggggtgcg acttgcccgg ctgccgcaaa aactactgat gccaccactg 6841 actaatccgc agattggcag tcaagcaccc aacttacagc cgttgctgtc tagtacgctg 6901 gataacagca acaactgctg gctgtggaaa aactttcctg atcccaatca gtatctgcta 6961 aatggaaacg gagggggtgc cgggagctcc tccagcaagt tgccacatct cacggccaaa 7021 ccagccacgg caactagtag ctccggagcg gccaacaaat cagcaggaag cctatttacc 7081 ctcaagcagc agcagcacca gcagaaactc atcgacaacg ctatcatgtc aaagataccc 7141 aaaagtctga cagtaatacc gcagcagatg ggtggtaata ccggtggcga tatggggggc 7201 agcagctcct ccggcaagga ctgatgacgg cgaaggaggg cgccatggcc attagccgta 7261 gcgccggagg taacccggcg aagtagtagg atcaacaagc aggcgacgtg cagcttaagc 7321 ggcgatcttc agaacaagag gtgaccagcg gcggctccat ggatatcaca aactccacaa 7381 ttccatggct gcagtagaat aagtgataca ctaaaaaaaa aaaaaaacat tggacggaca 7441 gaaaagaaac agatgagaaa ccaagataat tcttagatta cataacgttg tttgtgtata 7501 aacgagatac ggttacgaat acgattacaa tataagtacg cactagttag gcactcaagc 7561 cgatacgaca gatgcatgat ggagcagatg aagttcccga tgcgaatgcg atttaggata 7621 cggatatgga tagttaggga taccaatgca ccttactcta aactatgcta ctctataatt 7681 ttaggcttat aatatatttt tttaattaga tttacgggca tataaacttg cgattcgtgt 7741 attatagata ccaaaattgc tacagctaaa cggtttatac atttataagc gactccgaaa 7801 cacacacaca cacacacatc aactgctaca ccaaaacaca cacacacaaa gtaatttaag 7861 agagaatgca gcacaaaaaa attgaggcca agattataat ccaaccttag gctgctgctg 7921 aactgaaaag ggaagacagg atcccgcagc cccagttttt gcatgagctc caatcatgcc 7981 aggagctttt ccaccacaca cactatgctc acgtagcaca tagcaatcca atcctgcgta 8041 ttgaacgttt cttttgatgc agaatcctaa tttataaaca ttttgtattt ccatttatac 8101 atccaattca caagttactc cttcaagccc agcctcagtt actgaaagat caagataatt 8161 atgccgacct aaagttaatt ccaaaactgt acatatttta cggaatagac agataaatac 8221 aagaactata aaatacaatc taaaacgcta attcaaccat gcaaatctta attaaaagct 8281 taagaagaaa cgcgattgtg agccacaagc aatcaaattg atcgatgttc tcggtgcctc 8341 tggtggccta tgttccattc caaggaattc taaaatcgta gctgcctaaa ggcaaagcaa 8401 gatcgttggt agtaaagtga aattaatttg cttattttta atgacaaatt ggaaagcttt 8461 ctcgacatat ataccaataa aacatatact taacacccag catagacata tgcatatata 8521 tatatatata tacatatata tatctacaaa tatggattta tatacacact atactacatt 8581 tagatatttt agagagatgg cgagagatac aaatgtaaat tagtttgtta agcatagata 8641 tatttataca catatgagaa ttcaattgtt gttgttaaac attgaaaatg tatttaaaaa 8701 tcaggagttg attgatacca tgcaaaccaa acaagaaacg tgaacggaaa caaactttgg 8761 caagccgaag tttatatacc cttgcagaaa tttggaaatg ggctaaaacc ctgaaaatat 8821 acataaatac gatggatatt ggttcaagat gatacctctt agcacttaaa agttacttca 8881 gctgtacagt cttccctgtt gggcaaaact cttatgatct cccaataaca cttatcttac 8941 cttaaaagct ttatatactt gtccgatgtt aacaaattgg cttcaaattc attactttga 9001 atatggcagc cttacacatt cacatattaa gcaagaatag taaatcagtg gaatgattat 9061 ttattgattt cataaagcct ctgcaggggt ataacaaatg gaatgcttaa gtcctacgtc 9121 gttgcactgg tgcgggtgcg aatcggagct gaaagaggaa tggagcagtt cgcaggacta 9181 gcttctgatg accatgatga acttagattg ccttgatccg aacctggttt tgtaaagcgg 9241 catggaaatc gtgtgcctgt gggtgaatgt agtgtgtttg tgctgtgttt atgtagtact 9301 ttgtagctga tagatcattc gatccaaaca catcttaaaa ttacaactta tttatgcaat 9361 tatttttaaa ggattaccaa gaatcaaaat ttcaacgaac catgaat //