Dbfetch
LOCUS NM_001201708 6747 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster paralytic (para), transcript variant AP, mRNA. ACCESSION NM_001201708 VERSION NM_001201708.1 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 6747) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 6747) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 6747) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 6747) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 6747) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 6747) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 6747) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 6747) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 6747) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 6747) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 6747) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 6747) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 6747) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 6747) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 6747) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 6747) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 6747) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 6747) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 6747) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 6747) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 6747) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 6747) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 6747) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..6747 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..6747 /gene="para" /locus_tag="Dmel_CG9907" /gene_synonym="bas; bss; CG9907; Dmel\CG9907; DmNav; DmNav1; DmNa[[v]]; DmNa[[V]]; DmNa[[v]]1; l(1)14Da; l(1)ESHS48; lincRNA.S9469; Nav1; Ocd; olfD; par; Para; para13-5; sbl; sbl-1; Scn1alpha; Shu; Shudderer; VSSC" /note="paralytic" /map="14C8-14E1" /db_xref="FLYBASE:FBgn0285944" /db_xref="GeneID:32619" CDS 269..6562 /gene="para" /locus_tag="Dmel_CG9907" /gene_synonym="bas; bss; CG9907; Dmel\CG9907; DmNav; DmNav1; DmNa[[v]]; DmNa[[V]]; DmNa[[v]]1; l(1)14Da; l(1)ESHS48; lincRNA.S9469; Nav1; Ocd; olfD; par; Para; para13-5; sbl; sbl-1; Scn1alpha; Shu; Shudderer; VSSC" /note="CG9907 gene product from transcript CG9907-RAP; CG9907-PAP; para-PAP; bang sensitive; voltage-sensitive sodium channel; shudderer; bang senseless; bangsenseless; voltage gated sodium ion channel; paralyzed; Out-cold; Out cold; smell-blind; smellblind; paralytic; bang-senseless" /codon_start=1 /product="paralytic, isoform AP" /protein_id="NP_001188637.1" /db_xref="FLYBASE:FBpp0292709" /db_xref="GeneID:32619" /db_xref="FLYBASE:FBgn0285944" /translation="MTEDSDSISEEERSLFRPFTRESLVQIEQRIAAEHEKQKELERK RAEGEVPQYGRKKKQKEIRYDDEDEDEGPQPDPTLEQGVPIPVRLQGSFPPELASTPL EDIDPYYSNVLTFVVVSKGKDIFRFSASKAMWMLDPFNPIRRVAIYILVHPLFSLFII TTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMARGFILCPFTYLRDAWNWLD FVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVII LTMFSLSVFALMGLQIYMGVLTQKCIKKFPLDGSWGNLTDENWDYHNRNSSNWYSEDE GISFPLCGNISGAGQCDDDYVCLQGFGPNPNYGYTSFDSFGWAFLSAFRLMTQDFWED LYQLVLRAAGPWHMLFFIVIIFLGSFYLVNLILAIVAMSYDELQKKAEEEEAAEEEAI REAEEAAAAKAAKLEERANAQAQAAADAAAAEEAALHPEMAKSPTYSCISYELFVGGE KGNDDNNKEKMSIRSVEVESESVSVIQRQPAPTTAHQATKVRKVSTYTIRNGRGRFGI PGSDRKPLVLSTYQDAQQHLPYADDSNAVTPMSEENGAIIVPVYYGNLGSRHSSYTSH QSRISYTSHGDLLGGMAVMGVSTMTKESKLRNRNTRNQSVGATNGGTTCLDTNHKLDH RDYEIGLECTDEAGKIKHHDNPFIEPVQTQTVVDMKDVMVLNDIIEQAAGRHSRASDR GVSVYYFPTEDDDEDGPTFKDKALEVILKGIDVFCVWDCCWVWLKFQEWVSLIVFDPF VELFITLCIVVNTMFMAMDHHDMNKEMERVLKSGNYFFTATFAIEATMKLMAMSPKYY FQEGWNIFDFIIVALSLLELGLEGVQGLSVLRSFRLLRVFKLAKSWPTLNLLISIMGR TMGALGNLTFVLCIIIFIFAVMGMQLFGKNYHDHKDRFPDGDLPRWNFTDFMHSFMIV FRVLCGEWIESMWDCMYVGDVSCIPFFLATVVIGNLVVLNLFLALLLSNFGSSSLSAP TADNDTNKIAEAFNRIGRFKSWVKRNIADCFKLIRNKLTNQISDQPSGKGVCRCISAE HGDNELELGHDEILADGLIKKGIKEQTQLEVAIGDGMEFTIHGDMKNNKPKKSKYLNN ATDDDTASINSYGSHKNRPFKDESHKGSAETMEGEEKRDASKEDLGLDEELDEEGECE EGPLDGDIIIHAHDEDILDEYPADCCPDSYYKKFPILAGDDDSPFWQGWGNLRLKTFQ LIENKYFETAVITMILMSSLALALEDVHLPQRPILQDILYYMDRIFTVIFFLEMLIKW LALGFKVYFTNAWCWLDFVIVMLSLINLAAVWSGADDVPAFRSMRTLRALRPLRAVSR WEGMKVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCEDMNGTKLSHE IIPNRNACESENYTWVNSAMNFDHVGNAYLCLFQVATFKGWIQIMNDAIDSREVDKQP IRETNIYMYLYFVFFIIFGSFFTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYY NAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDIIIMLFIGLNMFTMTLDRYDAS DTYNAVLDYLNAIFVVIFSSECLLKIFALRYHYFIEPWNLFDVVVVILSILGLVLSDI IEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMF IFAIFGMSFFMHVKEKSGINDVYNFKTFGQSMILLFQMSTSAGWDGVLDAIINEEACD PPDNDKGYPGNCGSATVGITFLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTD DDYDMYYEIWQQFDPEGTQYIRYDQLSEFLDVLEPPLQIHKPNKYKIISMDIPICRGD LMYCVDILDALTKDFFARKGNPIEETGEIGEIAARPDTEGYEPVSSTLWRQREEYCAR LIQHAWRKHKARGEGGGSFEPDTDHGDGGDPDAGDPAPDEATDGDAPAGGDGSVNGTA EGAADADESNVNSPGEDAAAAAAAAAAAAAAGTTTAGSPGAGSAGRQTAVLVESDGFV TKNGHKVVIHSRSPSITSRTADV" ORIGIN 1 caacaacaac aatacaagca agcacgctca caacaaaagc agcaacagca acaacaacca 61 caatagcaac tacagcaaca acaacatcag cggatagagc gagcagccag gcacaacatc 121 gatagacatc gattaacgca tcgtgctaag cggcgggcgc taatcgaaca tggcgcctcg 181 gatatagttg tagctttaat gtagcaggcg acatccatgt gcctcatgcc ttggaaatct 241 aaggctctca tcgttggccg catagacaat gacagaagat tccgactcga tatctgagga 301 agaacgcagt ttgttccgtc cctttacccg cgaatcattg gtgcaaatcg aacaacgcat 361 tgccgctgaa catgaaaagc agaaggagct ggaaagaaag agagccgagg gagaggtgcc 421 gcaatatggt cgcaagaaaa aacaaaaaga aatccgatat gatgacgagg acgaggatga 481 aggtccacaa ccggatccta cacttgaaca gggtgtgcca atacctgttc gattgcaggg 541 cagcttcccg ccggaattgg cctccactcc tctcgaggat atcgatccct actacagcaa 601 tgtactgaca ttcgtagttg taagcaaagg aaaagatatt tttcgctttt ctgcatcaaa 661 agcaatgtgg atgctcgatc cattcaatcc gatacgtcgt gtggccattt acattctagt 721 gcatccatta ttttccctat tcatcatcac cacaattctc gtcaactgca tcctgatgat 781 aatgccgaca acgcccacgg ttgagtccac tgaggtgata ttcaccggaa tctacacatt 841 tgaatcagct gttaaagtga tggcacgagg tttcatttta tgcccgttta cgtatcttag 901 agatgcatgg aattggctgg acttcgtagt aatagcttta gcttatgtga ccatgggtat 961 agatttaggt aatctagcag ccctgcgaac gtttagggtg ctgcgagcgc ttaaaaccgt 1021 agccattgtg ccaggcttga agaccatcgt cggcgccgtc atcgaatcgg tgaagaatct 1081 gcgcgatgtg attatcctga ccatgttctc cctgtcggtg ttcgcgttga tgggcctaca 1141 gatctatatg ggcgtgctca cgcagaagtg catcaagaag ttcccgctgg acggttcctg 1201 gggcaatctg accgacgaga actgggacta tcacaatcgc aatagctcca attggtattc 1261 cgaggacgag ggcatctcat ttccgttatg cggcaatata tccggtgcgg ggcaatgcga 1321 cgacgattac gtgtgcctgc aggggtttgg tccgaatccg aattatggct acaccagctt 1381 cgattcgttc ggatgggctt tcctgtccgc cttccggctg atgacacagg acttctggga 1441 ggatctgtac cagctggtgt tgcgcgccgc cggaccatgg cacatgctgt tctttatagt 1501 catcatcttc ctaggttcat tctatcttgt gaatttgatt ttggccattg ttgccatgtc 1561 gtatgacgaa ttgcaaaaga aggccgaaga agaagaggct gccgaagagg aggcgatacg 1621 tgaagcggaa gaagctgccg ccgccaaagc ggccaagctg gaggagcggg ccaatgcgca 1681 ggctcaggca gcagcggatg cggctgccgc cgaagaggct gcactgcatc cggaaatggc 1741 caagagtccg acgtattctt gcatcagcta tgagctattt gttggcggcg agaagggcaa 1801 cgatgacaac aacaaagaga agatgtccat tcggagcgtc gaggtggagt cggagtcggt 1861 gagcgttata caaagacaac cagcacctac cacagcacac caagctacca aagttcgtaa 1921 agtgagcacg tacacgatac ggaacggacg tggccgcttt ggtatacccg gtagcgatcg 1981 taagccattg gtattgtcaa catatcagga tgcccagcag cacttgccct atgccgacga 2041 ctcgaatgcc gtcaccccga tgtccgaaga gaatggggcc atcatagtgc ccgtgtacta 2101 tggcaatcta ggctcccgac actcatcgta tacctcgcat cagtcccgaa tatcgtatac 2161 ctcacatggc gatctactcg gcggcatggc cgtcatgggc gtcagcacaa tgaccaagga 2221 gagcaaattg cgcaaccgga acacacgcaa tcaatcagtg ggcgccacca atggcggcac 2281 cacctgtctg gacaccaatc acaagctcga tcatcgcgac tacgaaattg gcctggagtg 2341 cacggacgaa gctggcaaga ttaaacatca tgacaatcct tttatcgagc ccgtccagac 2401 acaaacggtg gttgatatga aagatgtgat ggtcctgaat gacatcatcg aacaggccgc 2461 tggtcggcac agtcgggcaa gcgatcgcgg tgtctccgtt tactatttcc caacagagga 2521 cgatgacgag gatgggccga cgttcaaaga caaggcactc gaagtgatcc tcaaaggcat 2581 cgatgtgttt tgtgtgtggg actgttgctg ggtttggttg aaatttcagg agtgggtatc 2641 gctcatcgtc ttcgatccct tcgtcgagct cttcatcacg ctgtgcattg tggtcaacac 2701 gatgttcatg gcaatggatc accacgatat gaacaaggag atggaacgcg tgctcaagag 2761 tggcaactat ttcttcaccg ccacctttgc catcgaggcc accatgaagc taatggccat 2821 gagccccaag tactatttcc aggagggctg gaacatcttc gacttcatta tcgtggccct 2881 atcgctattg gaactgggac tcgagggtgt ccagggtctg tccgtattgc gttcctttcg 2941 attgctgcgt gtattcaaac tggccaagtc ttggcccaca cttaatttac tcatttcgat 3001 tatgggacgc accatgggcg ctttgggtaa tctgacattt gtactttgca ttatcatctt 3061 catctttgcg gtgatgggaa tgcaactgtt cggaaagaat tatcatgatc acaaggaccg 3121 ctttccggat ggcgacctgc cgcgctggaa cttcaccgac tttatgcaca gcttcatgat 3181 cgtgttccgg gtgctctgcg gagaatggat cgagtccatg tgggactgca tgtacgtggg 3241 cgatgtctcg tgcattccct tcttcttggc caccgttgtc atcggcaatc ttgtggtact 3301 taaccttttc ttagccttgc ttttgtccaa ttttggctca tctagcttat cagcgccgac 3361 tgccgataac gatacgaata aaatagccga ggccttcaat cgaattggcc gatttaaaag 3421 ttgggttaag cgtaatattg ctgattgttt caagttaata cgtaacaaat tgacaaatca 3481 aataagtgat caaccatcag gcaaaggcgt ttgtcgttgt atatctgcag agcatggtga 3541 caacgaactg gagctgggcc acgacgagat cctcgccgac ggcctcatca agaaggggat 3601 caaggagcag acgcaactgg aggtggccat cggggatggc atggaattca cgatacacgg 3661 cgacatgaag aacaacaagc cgaagaaatc caaatatcta aataacgcaa cggacgacga 3721 cactgccagc attaactcat atggtagcca taagaatcga ccattcaagg acgagagcca 3781 caagggcagc gccgagacga tggagggcga ggagaagcgc gacgccagca aggaggattt 3841 aggtctcgac gaggaactgg acgaggaggg cgaatgcgag gagggcccgc tcgacggtga 3901 tatcattatt catgcacacg acgaggatat actcgatgaa tatccagctg attgctgccc 3961 cgattcgtac tataagaaat ttccgatctt agccggtgac gatgactcgc cgttctggca 4021 aggatggggc aatttacgac tgaaaacttt tcaattaatt gaaaataaat attttgaaac 4081 agctgttatc actatgattt taatgagtag cttagctttg gcattagaag atgtacatct 4141 gccacaaaga cccatactgc aggatatttt atactatatg gacagaatat ttacggttat 4201 attcttcttg gaaatgttaa tcaagtggtt ggcgctcggc ttcaaagtgt acttcaccaa 4261 cgcgtggtgt tggctcgatt tcgtgattgt catgctgtcg ctaattaatt tggccgcggt 4321 ctggtccggg gccgatgatg tgcccgcctt tcgctcgatg cgaactctgc gcgccctgcg 4381 accactgcgg gcagtttcgc gctgggaggg catgaaagtc gtcgttaatg cgctggtaca 4441 agctataccg tccatcttca atgtgctatt ggtgtgtcta atattttggc taatttttgc 4501 cataatgggt gtacagcttt ttgctggaaa atattttaag tgcgaggaca tgaatggcac 4561 gaagctcagc cacgagatca taccaaatcg caatgcctgc gagagcgaga actacacgtg 4621 ggtgaattca gcaatgaatt tcgatcatgt aggtaacgcg tatctgtgcc ttttccaagt 4681 ggccaccttc aaaggctgga tacaaatcat gaacgatgct atcgattcac gagaggtgga 4741 caagcaacca attcgtgaaa cgaacatcta catgtattta tatttcgtat tcttcatcat 4801 atttggatca tttttcacac tcaatctgtt cattggtgtt atcattgata attttaatga 4861 gcaaaagaaa aaagcaggtg gatcattaga aatgttcatg acagaagatc agaaaaagta 4921 ctataatgct atgaaaaaga tgggctctaa aaaaccatta aaagccattc caagaccaag 4981 gtggcgacca caagcaatag tctttgaaat agtaaccgat aagaaattcg atataatcat 5041 tatgttattc attggtctga acatgttcac catgaccctc gatcgttacg atgcgtcgga 5101 cacgtataac gcggtcctag actatctcaa tgcgatattc gtagttattt tcagttccga 5161 atgtctatta aaaatattcg ctttacgata tcactatttt attgagccat ggaatttatt 5221 tgatgtagta gttgtcattt tatccatctt aggtcttgta cttagcgata ttatcgagaa 5281 gtacttcgtg tcgccgaccc tgctccgagt ggtgcgtgtg gcgaaagtgg gccgtgtcct 5341 tcgactggtg aagggagcca agggcattcg gacactgctc ttcgcgttgg ccatgtcgct 5401 gccggccctg ttcaacatct gcctgctgct gttcctggtc atgttcatct ttgccatttt 5461 cggcatgtcg ttcttcatgc acgtgaagga gaagagcggc atcaacgacg tctacaactt 5521 caagaccttt ggccagagca tgatcctgct ctttcagatg tcgacgtcag ccggttggga 5581 tggtgtactg gacgccatta tcaatgagga agcatgcgat ccacccgaca acgacaaagg 5641 ctatccgggc aattgtggtt cagcgaccgt tggaataacg tttctcctct catacctagt 5701 tataagcttt ttgatagtta ttaatatgta cattgctgtc attctcgaga actatagtca 5761 ggccaccgag gacgtgcaag agggtctaac cgacgacgac tacgacatgt actatgagat 5821 ctggcagcaa ttcgatccgg agggcaccca gtacatacgc tatgatcagc tgtccgaatt 5881 cctggacgta ctggagcccc cgctgcagat ccacaaaccg aacaagtaca agatcatatc 5941 gatggacata cccatctgtc gcggtgacct catgtactgc gtcgacatcc tcgacgccct 6001 tacgaaagac ttctttgcgc ggaagggcaa tccgatagag gagacgggtg agattggtga 6061 gatagcggcc cgcccggata cggagggcta cgagcccgtc tcatcaacgc tgtggcgtca 6121 gcgtgaggag tactgcgccc ggctaatcca gcacgcctgg cgaaagcaca aggcgcgcgg 6181 cgagggaggt gggtcctttg agccggatac ggatcatggc gatggcggtg atccggatgc 6241 cggggacccg gcgcccgatg aagcaacgga cggcgatgcg cccgctggtg gagatggtag 6301 tgttaacggt actgcagaag gagctgccga tgccgatgag agtaatgtaa atagtccggg 6361 tgaggatgca gcggcggcgg cagcagcagc agcagcagcg gcggcggcgg gcacgacgac 6421 ggcgggaagt cccggagcgg gtagcgccgg gcgacagacc gccgttctcg tggagagcga 6481 cgggttcgtg acgaagaacg gccacaaggt ggtcatccac tcgcgatcgc cgagcatcac 6541 gtcgcgcacg gcggatgtct gagccaggcc tcgccccccc ctccaagatg cacgcgagta 6601 ttagcatgag tacgtgttgg atgttgcatg ttgcatcagc gatgcagcag cgacagtgag 6661 ctaacaacaa cagcaacaag gcgaacaaca agcataattt tctgctatat aatgaaagaa 6721 caccatacaa acaaatacaa caacaat //