Dbfetch
LOCUS NM_001169834 7362 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster enhancer of bithorax, transcript variant F (E(bx)), mRNA. ACCESSION NM_001169834 VERSION NM_001169834.2 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 7362) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 7362) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 7362) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 7362) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 7362) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 7362) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 7362) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 7362) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 7362) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 7362) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 7362) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 7362) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 7362) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 7362) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 7362) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (10-NOV-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 7362) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 7362) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 7362) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 7362) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 7362) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 7362) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 22 (bases 1 to 7362) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 7362) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 24 (bases 1 to 7362) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 25 (bases 1 to 7362) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jan 16, 2013 this sequence version replaced NM_001169834.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..7362 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="3L" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..7362 /gene="E(bx)" /locus_tag="Dmel_CG32346" /gene_synonym="CG10894; CG17135; CG32346; CG32478; CG7022; Dmel\CG32346; dNURF; dNURF301; e(bx); e(Bx); E(Bx); E(BX); Ebx; En-bx; l(3)122; l(3)ry122; Nurf; NURF; NURF 215; Nurf 301; Nurf-215; NURF-215; NURF-301; NURF215; nurf301; Nurf301; NuRF301; NURF301; p215; p301" /note="Enhancer of bithorax" /map="61B2-61B3" /db_xref="FLYBASE:FBgn0000541" /db_xref="GeneID:44811" CDS 226..6645 /gene="E(bx)" /locus_tag="Dmel_CG32346" /gene_synonym="CG10894; CG17135; CG32346; CG32478; CG7022; Dmel\CG32346; dNURF; dNURF301; e(bx); e(Bx); E(Bx); E(BX); Ebx; En-bx; l(3)122; l(3)ry122; Nurf; NURF; NURF 215; Nurf 301; Nurf-215; NURF-215; NURF-301; NURF215; nurf301; Nurf301; NuRF301; NURF301; p215; p301" /note="CG32346 gene product from transcript CG32346-RF; CG32346-PF; E(bx)-PF; nucleosome remodeling factor; nucleosome remodeling factor - 215kD" /codon_start=1 /product="enhancer of bithorax, isoform F" /protein_id="NP_001163305.1" /db_xref="FLYBASE:FBpp0290563" /db_xref="GeneID:44811" /db_xref="FLYBASE:FBgn0000541" /translation="MSGRGSRKRGRPPKTPNERASGRFNYQLLKKPKYLSEGKSQPST PSASRGISPQSDEGSRSSHNNHTNRSRGSAAKRGRGRKSAVQPNTSSYSGRKGYESEY HYGSDFGDSEEDKSDNEDDMLLTPSDDESLEVANESESEFSVCSFNQNGVGRPPRPPS PEPVWLQEGRQYAALDLPDSSEDLFIANTHVLRALSIYEVLRRFRHMVRLSPFRFEDL CAALACEEQSALLTEVHIMLLKAILREEDAQGTHFGPLDQKDTVNISLYLIDSITWPE VLRSYVESDKTFDRNVFHILSHTEYPYTGIDNRLEVLQFLSDQFLTSNSIRDVMLQEG PIHYDDHCRVCHRLGDLLCCETCPAVYHLECVDPPMNDVPTEDWQCGLCRSHKVSGVV DCVLPQEKQGVLIRHDSLGVDRHGRKYWFIARRIFIEDQENFTCWYYSTTSKLKLLLS RLDAEELETRLHSQITERRDEIERQMKLTETLTNEHKHTKRSVIEIEQEAKNELLEKE VLDEDEKDGDAKSESQSIEGTKKQEECKMVTRQKSNQLTNGTLHFKLGMEQGFKNYVN QYSTNPIALNKPQRNEERDKRRHLSHKFSLTTASDFKWIGITMGTTDNMITTLRQTLI NFESNIAASFLNINWVVNKKIWNAAVMNARRPSEFAVVLLLFQASLKSVVFANVWHEQ LGHTTLQRITSAEREERKKLEKREKRERDDEEERNRLAFNYIKYTLGLKHQVWKQKGE EYRVHGQWGWLWLSSSRRCGVRARRAQPLTHNRVYVHYTMGEENDVNEIILVDPRTQR FMQQCESSNVDGQVCHYLPDQYKNVKVIEDVTEKIKGHIDVSKALNAPGRTYYSKVAR KSRLDDLLDRRLKLAEVEEQMASKIPSDMKPLLVSSQNNTANSKQTFLEKRLLRLTEV QAKGGPANVNLELVNSLAKQIQTVRLQFSQLNRFAKVFRCYTKECNTNSNAVSQITQN TCYSPLCLQKARAKKELLLLLRKAHTAGNGSKETVAAILGAVKKPSILEQKLTEGKRE STQVAVDDSEEGKPAESEAPLDLLQDWEHARAHAVPFSDSLLTECILVDQECVTNTKI KQEVNASSGCNTTPDSNTQDSDKIDYIESMDVCSNVEIESTEDSIVTGLNSGNAEDVD MTPGWRRKRNQKSKKSYIGTKDVLDQTLDKDIPLNKQNRRFPITARPVKRECVKKYER ETFENGNERVYSTSSPRGRVYLLNDAAKLYEQAVKTEDKSTITKKPSYSRYPLISNFL THKKKRSLLVLPRFELLKLARLGGKSSTNGFHHAAKNNTIWQYQCSRPLFRTCWSYRT SNATSLSSLALQLRILWSCLRWDDMIAKPPSTDGKHQVTTDTEIVTLELLKLRHSGRY GEKTSYLRRKVVIPLEMPKTVREVTSIRSGLRKRKRAESPQPTEPQITEEWVDEDKLE LWEIKFMGEKQEKARLSAVTRSVASRQLEASGSNGSNTSTNGALGVAGRVQLAPKLSE DVKEKMEQQLKLQRAVHQQRKLVATGEITRSVTPVKGQVIGSRRVIVKNPDGTTRIIQ QAVTQVSRTGGANTAAAAASPTVGGSTSTQSNPSTSTPHKVQIIRGPDGKVSVRGLNP GQQLVQMPDGKLHVLTTTTSSNSAGQGNKMKVPIKPASTSSSPAISSAQTTTNPVTPV IKQIAVKHVTKNSATQSIASSSRVALPLAQIKNKLLLAQQQQQSTSSSPATSSSPVQK IVSKVVNTSTSGQTLQQVFVQSGSKLVVGQNAQGQKVIISTSAAQQQGTSPVQQQQLV QSQPIQQSPQQISMTQQQIVVGGQRIILSPGQTIVTQRNVPQSQALQMVQQQIQTQQQ QQQHHVVQPQQQFVVQSNQIVQSSPSAQTKLVKQLVVQQQSQQTIEEKTQITTTDSNE TGTQQVLVPNSTLAQQLAQGKLQVATVNGQQVIVKPLGNNQAQIVAHIKHQGDGNAHI VTSNSATAVPQANPQTSPVKQQALPPQSPQQVVVQQQQIHQQSPTNFESGVTPITQQP VLTQAVQAPAQQQALSVEESLLQNQPPGTVIKCVTAQVLQTEHGPRIVLQGLVGNDFT AQQLQLVQTQVKQQLMKAQESNGKLGVLGPTKIYLAVQPENAVQSQPPPLTPVHQSAA HQQVSSF" ORIGIN 1 tagctatgtt caaaactgta atgttaggta aaagtctctt tcgcagtgtg ctgaagatag 61 ttaaaaatat tagaatatat cgtgttaaat cctgtgcaat tattccgcaa catgctggat 121 ctaatgtgca gcctcgcagc attaacttgg aacaatatct gaggagagta cccccacgca 181 cccctgcaca cagccagata aatacgcaag gcgaaaacaa acaagatgag cggtcgcggc 241 agccgtaaac gtggacgtcc gccaaagacg cccaacgaac gcgcatcagg acgcttcaat 301 taccagcttc tcaagaagcc gaagtatctc agcgagggaa agtcgcagcc cagcactccg 361 tcggcatcca ggggcatttc tccacagagc gacgagggca gcaggagcag ccacaacaac 421 cacaccaatc gcagtcgcgg gagcgccgct aagaggggac gaggccgcaa atccgccgtg 481 caaccgaaca ccagtagcta ctctggaagg aaagggtacg agtcggagta tcactacggg 541 tcagattttg gggattccga agaagataaa tccgataatg aggatgatat gctgcttact 601 cccagcgacg acgagagcct agaagtagcc aacgagagcg aatcagagtt ttccgtgtgc 661 agctttaacc aaaatggagt tggtcggccg ccacgtcctc ctagcccaga acctgtgtgg 721 ctgcaggaag gtcgtcagta tgcagcgctt gatttgccgg actcgtcgga ggatcttttc 781 attgctaata cacacgtttt gcgcgcgcta agtatctatg aagtactgcg acgatttcgc 841 cacatggtcc gcctttcacc attccgattt gaagacttgt gtgcagcgct ggcttgtgag 901 gagcaaagtg cattattgac ggaggtacac ataatgctgc ttaaagcgat tcttcgagaa 961 gaggacgcgc agggtacaca ttttggcccg ctggatcaaa aagatacggt taatataagt 1021 ctttacctga ttgactctat aacgtggccg gaagttttgc gaagctatgt agaaagcgat 1081 aagacatttg atcgcaacgt gtttcacatt ttaagccaca ctgaataccc ttacacgggc 1141 attgacaacc ggcttgaagt gctccagttt ctgtcagatc aatttttaac ttccaattct 1201 atacgagatg taatgctgca ggagggacct attcattatg atgaccattg ccgagtgtgc 1261 catcggctcg gtgatttatt atgttgcgag acgtgccctg ctgtctatca tttggaatgt 1321 gtagacccgc caatgaatga cgtacctact gaggattggc agtgcgggct ttgccgctcg 1381 cataaggtaa gtggcgtagt ggactgcgtg ttgccacaag aaaaacaagg cgtgctaatc 1441 cggcatgata gcctcggtgt tgatcgtcat gggcgcaaat attggtttat tgcacgtcgc 1501 atttttatcg aggatcagga gaactttaca tgctggtatt acagtacgac aagtaagtta 1561 aaattgctgc tcagtcgact ggacgccgaa gaactggaaa ctcgtctgca tagccagatt 1621 acagaaagga gagacgaaat cgagcgccaa atgaaactga ctgagacctt aaccaatgaa 1681 cacaaacaca cgaagcgtag tgttatcgaa atcgaacaag aggctaaaaa tgaacttttg 1741 gagaaagagg tgcttgacga ggatgaaaaa gatggtgatg ctaaatctga gagtcaatct 1801 atagagggaa caaaaaaaca agaagaatgt aaaatggtca cgcgtcaaaa atccaatcag 1861 ctgactaatg gtactttgca ttttaaactt ggcatggagc aaggatttaa gaactatgtc 1921 aaccagtatt caacaaatcc aattgcactc aacaagccgc aacgaaacga ggagcgagat 1981 aagcgacgcc atctgtccca taagttctcg ttaacgacgg cttctgactt taaatggatc 2041 ggtataacca tgggaactac tgacaatatg ataacaactc taaggcaaac attgataaac 2101 ttcgaatcca atatagcagc ttccttttta aatattaact gggtagttaa caaaaaaatt 2161 tggaatgctg cggtgatgaa cgcccgtcga ccttctgaat ttgcggtagt attgttactt 2221 tttcaagcgt cccttaagag cgttgttttt gccaacgtct ggcatgagca actcggacac 2281 acaactttgc aacgcataac tagtgccgaa cgagaggagc gaaaaaaact agaaaagcga 2341 gagaagcgcg agcgggatga tgaggaagaa cgtaatcgct tagcatttaa ctacataaag 2401 tataccctgg gtctcaaaca tcaagtctgg aagcaaaaag gagaagaata ccgggtccac 2461 gggcaatggg gctggctttg gctctcaagc agtcgacgct gtggtgttcg tgcacgtcga 2521 gcccaacctc taacacacaa tagagtctac gtacattaca ccatgggaga ggaaaacgac 2581 gtaaatgaaa ttattttagt cgacccacgc acccaacggt ttatgcaaca atgtgagtca 2641 agcaatgtcg atggtcaggt gtgtcattat ttaccggacc aatataaaaa tgtgaaagtt 2701 atagaagatg ttacggagaa aatcaaaggg cacatcgacg tcagcaaagc gctaaatgct 2761 ccaggccgta cttattattc aaaagtggct cgcaaatcta gattagatga cttattggat 2821 cgccgtttaa agttggccga ggtcgaggag cagatggctt ctaaaattcc ttctgatatg 2881 aagccgcttc ttgtttcttc ccaaaataat acagccaaca gcaaacaaac gtttctagag 2941 aagcgtttac ttcgccttac tgaagtccaa gcaaaggggg gtcctgcaaa cgtaaacttg 3001 gaacttgtta attcgctggc taaacaaatt caaaccgtgc gcttacaatt tagtcagctt 3061 aatcgatttg ctaaagtttt tcgttgttat acaaaggagt gtaacaccaa ttcaaatgct 3121 gtctctcaaa taacccaaaa tacttgctac tctcccttat gtcttcaaaa agctcgggcc 3181 aaaaaagaac ttcttttgtt gttacgaaag gcgcatactg ccggtaatgg ctcaaaagag 3241 acagttgccg ctattttggg cgctgttaaa aagccatcta ttctcgagca gaagctgacg 3301 gagggtaaaa gagaatccac tcaggtggcc gtggatgatt ctgaagaggg gaagccagct 3361 gaatccgaag cgccgttgga tttacttcaa gattgggaac atgcacgagc gcacgccgtt 3421 ccttttagcg attctttatt gaccgaatgc atcctggttg accaggagtg cgtaaccaac 3481 acgaaaatta aacaagaggt gaatgccagt tccggatgca atacaactcc tgactcgaac 3541 acacaagact ccgataaaat agactatatt gagagtatgg acgtttgtag taatgttgaa 3601 attgagagta ccgaagattc cattgttacg ggcttaaact ctggtaacgc tgaagatgtc 3661 gatatgacac ctggatggcg gcgaaagcgt aaccagaaat cgaaaaaaag ctacatcggc 3721 actaaagatg tgttggatca gacgttagac aaggatatac cacttaacaa acagaaccgc 3781 agatttccta ttactgcacg tccggttaag cgcgaatgtg tcaaaaaata cgaacgagag 3841 acatttgaga atggaaacga gcgggtctat tcgactagtt cacctcgggg tcgtgtatac 3901 ctccttaatg atgcggccaa gttgtatgag caagctgtca aaactgagga taagtcaacg 3961 ataactaaaa agccatcata ctctcggtat ccacttatat ccaattttct tactcataaa 4021 aaaaagcgta gccttttagt gctaccacga tttgagctcc tgaagctggc tcgtctgggt 4081 ggaaaatcat cgacaaatgg ttttcatcac gctgcgaaaa ataacacaat ttggcagtat 4141 cagtgctcgc gtcccctctt ccgaacctgc tggtcctaca gaacatctaa tgccacgtcc 4201 ttatccagcc tagcacttca gcttcgaata ttgtggtcgt gtctccgctg ggatgacatg 4261 atagcaaagc ccccatccac ggatgggaag catcaggtta ctacggatac tgaaattgta 4321 acattggaat tgctcaaact tcggcactca ggacgctatg gtgaaaaaac aagctatttg 4381 cgacgaaaag ttgttattcc acttgaaatg ccgaagactg taagagaagt aacatccata 4441 cggtccggac tgcgaaaacg aaagcgtgct gaatctcctc agccaaccga gccacaaatt 4501 accgaggaat gggtcgacga agataaattg gagttatggg aaattaaatt tatgggagaa 4561 aaacaagaaa aggcacgcct atcagctgtt acgcgatctg tagcatcccg tcaattggag 4621 gcaagtggta gtaatggttc caacacttca actaatggag ctcttggcgt cgccggacgc 4681 gtccaactgg cacccaagtt gagtgaagat gttaaagaaa aaatggaaca acaattaaaa 4741 ttacagcgcg ctgttcatca gcagagaaaa ttggttgcaa ctggcgaaat aacccgttct 4801 gtgacaccag ttaaaggcca agttatcggt agcaggcgtg tcattgttaa aaaccctgat 4861 ggcacaactc gaattattca gcaggcagta acacaggttt caagaacagg aggagctaat 4921 actgcagcag cagctgcttc acctactgta ggaggctcga caagcactca atcaaatcca 4981 tccacatcta caccgcataa agtacaaatt ataaggggcc cagatggcaa agtaagcgta 5041 cgcgggttga atcctgggca gcagctggtt caaatgccgg atggaaaact ccatgtgctg 5101 actaccacaa catcttcaaa ttcggcgggg caaggaaaca aaatgaaggt tcccattaag 5161 ccagcttcta cttcgtcgtc accggcaatc agttcagcac agactactac aaatccagtg 5221 acgccagtga taaagcaaat tgcagttaaa catgtcacga aaaattctgc gacccaatcc 5281 atagcatcat cctcgcgcgt agccttaccg cttgctcaaa ttaagaataa gttgttactg 5341 gcccaacagc agcagcaatc aacatcttca tcaccagcaa cttcatcatc ccctgtgcaa 5401 aagatagtgt cgaaagtggt taacactagt acctctgggc aaactctaca gcaagtattc 5461 gtacagtctg ggtcaaaact ggtagtgggc caaaatgcac aagggcaaaa ggttattata 5521 tctacatcgg cggcacaaca gcaaggaaca tcaccggttc aacagcagca actagtacaa 5581 tcgcaaccaa ttcagcagtc accacaacag atctccatga cacagcagca gatagtagtt 5641 ggcggtcaac ggattatctt aagccccggt caaactattg ttactcagag gaatgtgccg 5701 cagagtcaag cattgcagat ggttcagcag cagattcaaa cccagcagca gcagcaacaa 5761 catcatgtcg tccagcctca gcaacaattc gttgttcaat caaaccaaat tgtacaatct 5821 tcgccaagtg cacaaaccaa actggttaaa cagcttgtgg ttcaacaaca atcgcagcaa 5881 accattgaag aaaaaacgca aatcaccacg actgatagca atgaaactgg cacacaacaa 5941 gtcttggttc caaattcaac tttagcccag cagttagcac agggcaaatt gcaggtggca 6001 acagtgaatg ggcaacaagt aatcgtaaaa ccgttgggaa ataatcaggc tcaaatcgtg 6061 gcacatatta aacaccaagg tgatgggaac gctcacatcg ttacaagtaa ttcagctact 6121 gcagtacctc aagctaaccc gcagacctca ccagtcaagc aacaggctct cccaccacaa 6181 agtccacaac aagtcgttgt gcagcagcag caaatacatc aacagtcacc cacaaacttc 6241 gaaagtggcg ttaccccaat aactcagcag ccggttctca cccaggctgt ccaggctcca 6301 gcccaacagc aagccttgag tgttgaggaa agtcttctgc agaatcagcc gcctggaaca 6361 gtaattaaat gtgtcaccgc tcaagtattg caaaccgagc atggtccacg tatagtattg 6421 caaggcctgg tgggcaacga tttcactgca caacaactgc aattggtgca aacgcaggtg 6481 aagcagcaac taatgaaggc tcaagagtca aatggcaaac ttggtgttct aggcccaaca 6541 aaaatatact tggcggtaca gccggaaaat gcagttcaat cacagccacc tcctctaacc 6601 cctgttcacc aatcggctgc gcatcagcaa gtgagtagtt tttagttata attataatgt 6661 aaaagtataa atgaggaata ggaacaggac tgtgagggtt gcatttgctg attctcgacc 6721 gaaatgccaa tttgtttttt gttccatcct acgtttaagt taagtttttt atttattcaa 6781 cccgagcggc atgtcgctgc ttcacttgca ctttctatac gtttcgtttg gtacacctaa 6841 tttgtttgtt tgttgtattt taatgaacat gaattgaata cattgcgttt cctaatttgt 6901 atacattcct aagctgtaaa caataactta tagtttccaa gtacagcaac agacttattg 6961 aaatatgaac caaggcttac tattgcaaaa taattattca acaagcaatt ctccacacag 7021 gagctcgata tttaaaaata catgataccg aataattact taaatatgtc atatttattt 7081 tgtttacata atttaaaaaa tataaaaatg tatttagcct aaaagtgtga ataccttatt 7141 aaatataagt aaatattaca tagtgagtag gaagcacatt aagcttatta acttaacaat 7201 aatccagact gtcacctaat gttaaaaacc aaggcaaaag tattagaaca actttgctcc 7261 gattagcttt tcttgcctga gggacatttg gtttcttagt aatacatcga atatttgtaa 7321 attgtaaagc gcattttgca ataaaaccta ttatgcaact ac //