Dbfetch
LOCUS NM_001169526 5291 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster cytoplasmic linker protein 190, transcript variant N (CLIP-190), mRNA. ACCESSION NM_001169526 VERSION NM_001169526.1 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 5291) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 5291) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 5291) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 5291) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 5291) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 5291) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 5291) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 5291) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 5291) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 5291) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 5291) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 5291) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 5291) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 5291) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 5291) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (10-NOV-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 5291) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 5291) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 5291) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 5291) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 5291) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 5291) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 22 (bases 1 to 5291) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 5291) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 24 (bases 1 to 5291) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 25 (bases 1 to 5291) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..5291 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="2L" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..5291 /gene="CLIP-190" /locus_tag="Dmel_CG5020" /gene_synonym="CG5020; Clip- 190; clip-190; Clip-190; clip190; Clip190; CLIP190; D-CLIP-19; D-Clip-190; D-CLIP-190; D-CLIP-195; D-CLIP-90; Dmel\CG5020" /note="Cytoplasmic linker protein 190" /map="36C7-36C7" /db_xref="FLYBASE:FBgn0020503" /db_xref="GeneID:35042" CDS 202..4998 /gene="CLIP-190" /locus_tag="Dmel_CG5020" /gene_synonym="CG5020; Clip- 190; clip-190; Clip-190; clip190; Clip190; CLIP190; D-CLIP-19; D-Clip-190; D-CLIP-190; D-CLIP-195; D-CLIP-90; Dmel\CG5020" /note="CG5020 gene product from transcript CG5020-RN; CG5020-PN; CLIP-190-PN; cytoplasmic linker protein-190; cytoplasmic linker protein 190" /codon_start=1 /product="cytoplasmic linker protein 190, isoform N" /protein_id="NP_001162997.1" /db_xref="FLYBASE:FBpp0290656" /db_xref="GeneID:35042" /db_xref="FLYBASE:FBgn0020503" /translation="MSRESDDNLSSINSAYTDNSSAVLTANTEQFIIGQRVWLGGTRP GQIAFIGDTHFAAGEWAGVVLDEPNGKNDGCVSGKRYFQCEPKRGIFSRLTRLTTYPL AGAQTPTSPLAKSSPDRSRTVSPTASIRSSMLRSPGIGGKNGMAVGDRVIVSSGFGSR PGILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFVPIAKVSLSP SSKKTRLSRTGSRESLTSIGTMNSIATTATSRMRMNAQQRKSSTPVKPILATPKSQFS MQDLLREKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALDNERKKT EELQCSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILPPDLPSDDG ALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEA LEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLK ATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDM LRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVRE MTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVES GESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALK VVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQ LEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALE KVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKE LTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEV TKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQV ANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKET HLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEE LVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEA AKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVK SQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQK KSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEF DTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRR QLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQK NDALKAKVQTLETLPMDFTKPHAFDALTKRKPAPRLFCDICDEFDQHDTEDCPIQGSE DQDYSTPSSESNNNEKERKLPAPRKYCDSCEVFGHDTSECADDETY" ORIGIN 1 agttacttga acgacttttc gcgaggcgga cgtgtttcag acgcggaatt gcaactcaga 61 tggcaaccaa ttgaacttga tcggctctat actatagctt atatagtgaa cacgcaaacg 121 aaattgaaaa tccaaaatag aagccaactt taacagagag acttacttat tgttatacaa 181 ctcacaaaag aagccaccag catgagtcgt gaaagcgatg acaatttaag ttcgatcaat 241 tcggcttata cagataacag cagcgccgtg ctgacagcaa acacagagca gttcatcatt 301 ggacagcggg tttggctggg tggcactcgt cccggacaga ttgccttcat tggagacaca 361 cactttgctg ctggcgaatg ggcgggtgtt gtccttgacg agcctaatgg taaaaacgat 421 ggctgtgtgt cgggcaaaag gtacttccag tgcgagccga aacgaggcat tttctcacgc 481 ctcacacgtc ttaccacata tcccttggcc ggagcccaga ctccgacctc tccattggcc 541 aaaagctccc cagacagatc gcgcacagtt tctccaactg cgagtattcg cagctctatg 601 cttcgcagtc ccggcattgg aggcaagaat ggaatggctg tgggcgatcg tgtgattgtc 661 tcttctggat ttggtagtcg tcctggtatc ttacgctatt tgggagagac acagtttgct 721 cccggcaact ggtgcggtgt ggaattggat gagcctagcg gcaaaaacga tggaactgtc 781 gatgatatca gatactttga gtgcaagccc aagtacgggg tgtttgtacc tattgcgaag 841 gtttcactgt cgccgtcgtc caagaaaacg cgtctttcca ggaccggatc aagggagtcg 901 ctcacctcga ttggcaccat gaacagcatc gccaccacgg ccacgtcgcg catgcgcatg 961 aatgctcagc agcgcaagtc gagcacgccc gttaagccaa ttttagcgac gccgaaaagc 1021 caattttcca tgcaggatct gctgcgcgag aagcaacaac atgtggagaa gctgatggtg 1081 gagcgcgacc tggaccgcga ggatgcccag aaccaggcgc tgcagctgca gaagaacatc 1141 aacgagctaa aagcaagaat cgttgaattg gagtcggcat tggacaatga acgaaagaaa 1201 actgaagaat tgcagtgctc catagacgaa gcccagtttt gtggcgatga attgaatgct 1261 cagtcacagg tttacaagga aaaaatccat gatctggagt caaaaatcac aaaactggtg 1321 tccgccacgc caagcctaca aagtatacta ccgcccgatc taccttcaga cgatggtgct 1381 ttgcaggagg aaatcgccaa gctgcaggaa aagatgacca ttcagcagaa ggaggttgaa 1441 tctcggattg cggaacagct ggaggaggag cagcggttga gggaaaatgt aaagtacctt 1501 aatgagcaaa tcgccactct acagtccgag ttggtgtcca aagatgaggc cctggagaaa 1561 ttctccctct cggaatgtgg catcgagaat ctccgaaggg aactcgaact tctcaaggag 1621 gagaacgaaa agcaagctca ggaggctcag gctgagttca cccgaaaact agccgaaaaa 1681 tccgtagagg tgttaagatt aagctctgaa ttgcaaaact tgaaggcaac atccgattcc 1741 ctggaaagcg aaagggttaa caaaaccgac gaatgtgaaa ttcttcaaac cgaagtacga 1801 atgcgggatg agcaaatcag agagctaaac caacaactcg atgaggttac cacacaacta 1861 aatgtacaaa aagcggatag ttctgctctg gatgatatgc ttcgattgca aaaggagggt 1921 actgaagaaa aatctactct tttagagaaa accgaaaagg agctagttca aagcaaagaa 1981 caagctgcga aaactctaaa tgataaggaa caacttgaaa aacagatatc agatttaaag 2041 caattggcgg aacaagaaaa actagtcagg gaaatgactg aaaatgcaat caatcaaata 2101 caactagaaa aagaatccat agaacagcaa ttggctttaa aacaaaacga acttgaggac 2161 ttccaaaaga aacagtcaga atcggaagtt catcttcagg aaatcaaagc tcagaacacg 2221 cagaaggatt ttgaattagt tgaatctggt gagtccctta aaaaactgca acagcaattg 2281 gagcagaaaa ctttgggtca tgaaaaactg caagctgctt tggaagaact aaagaaagaa 2341 aaggaaacga tcataaagga aaaggagcag gagctccagc agctccaaag caagtcagct 2401 gaatccgaaa gtgctttaaa agtcgtacaa gtacaactag agcaactcca gcaacaggct 2461 gccgcatctg gagaagaggg atccaaaact gtggccaaat tgcacgatga gattagtcag 2521 cttaagtccc aagctgaaga aactcagtcc gagttaaaat ccacccaatc caacttggaa 2581 gccaaaagca aacaattgga ggcagcaaat ggcagcctag aagaggaagc caagaagtca 2641 ggccatctgc tggaacagat taccaaactt aaatctgaag taggggagac gcaggcagct 2701 ctcagttcat gtcatacgga tgtggaatcc aaaactaagc aacttgaagc cgcaaatgca 2761 gctctggaga aggtcaacaa ggaatacgcg gaatcccgag cggaggcttc tgatctgcaa 2821 gataaggtga aggagatcac cgatacgcta catgctgagc ttcaagctga acgatcgtcc 2881 tccagtgctc tccatactaa gctgtccaag ttctcggatg aaatagctac cggccacaag 2941 gaactgacca gcaaagccga tgcctggagc caggagatgc tgcaaaaaga gaaggaacta 3001 caggagctgc gacagcaact tcaagatagt caagactctc aaacaaagct gaaagcagag 3061 ggagagcgga aagaaaagtc tttcgaggaa tctataaaga atcttcagga agaagtcact 3121 aaggccaaga cggagaatct agagctaagc actggcacac agacgaccat aaaggacctg 3181 caggagcgac tggaaatcac caatgctgag ctccagcaca aggaaaaaat ggcaagcgaa 3241 gatgcgcaga agattgccga ccttaagacc cttgtggaag ccatccaggt ggctaatgcc 3301 aatatatcag ctacaaatgc ggagctctcc actgtattgg aagttcttca ggcggagaag 3361 agtgaaacaa atcacatatt cgagctcttt gaaatggaag ccgatatgaa ctcagagcgg 3421 ttgatcgaaa aagttactgg gattaaggag gaactaaagg aaacccatct gcaactggat 3481 gagcgacaga aaaagttcga ggagttggag gagaaattga agcaagctca gcaaagtgaa 3541 caaaagttgc aacaggagtc tcagacttcc aaggagaaac ttacggaaat acaacaatcc 3601 ttgcaagaac tccaagattc tgtaaagcaa aaggaagaac ttgtccagaa cttggaagaa 3661 aaggttaggg aaagcagttc catcatagaa gcgcagaaca cgaaactaaa tgaaagcaat 3721 gttcagttgg aaaacaaaac ttcttgttta aaggaaaccc aagatcaatt gctagagtca 3781 cagaagaagg agaaacaatt gcaggaagag gctgccaaac tttccggtga gctgcagcaa 3841 gtgcaagagg ccaatggaga cataaaggat tccctagtaa aagtagagga actagtaaag 3901 gtgttggagg aaaaactcca agcagccacc tcccagttgg atgcccaaca agccacaaat 3961 aaggaactcc aggagttgct ggttaaatct caagaaaacg agggaaatct gcaaggagaa 4021 tctttggcag tcactgagaa actacaacaa ctggagcaag caaatgggga gcttaaggag 4081 gctctgtgtc aaaaagagaa tggccttaaa gaacttcagg gcaaacttga tgaaagtaat 4141 actgtattag aaagtcaaaa gaagagccac aacgaaattc aggataagtt agaacaggcc 4201 cagcaaaagg agaggactct tcaagaggaa acatccaagt tggcggagca actgagccaa 4261 ttaaagcagg ctaatgaaga gctccagaaa tcccttcagc aaaagcagtt acttttggaa 4321 aagggtaatg aattcgacac ccagctggca gaatatcaga aagtcattga tgagatggat 4381 gatgcggctt ccgttaaatc cgcgctgctg gaacagctac aaaatagagt tgcggaactg 4441 gagaccgcac tccgtcaagc caacgatgcc caaaagactg cttatctgga gactaaggaa 4501 ctgaggcgcc agctggaatc gctggaactg gagaagtcga gggaggttct gagcctaaag 4561 gctcagatga atggtgcgag cagtaggtcc ggaaagggtg atgaagtgga gtcactggac 4621 atcgaaacca gtcttgccaa gattaacttc ctgaactcaa ttattgctga catgcagcag 4681 aagaatgatg cactcaaggc aaaggtgcag acccttgaaa ccttgccaat ggatttcacc 4741 aaacctcatg ccttcgatgc cctgacaaag cggaaaccgg ctcccagact tttctgcgac 4801 atctgcgatg agtttgatca gcacgatacg gaggattgtc caatccaggg aagcgaagat 4861 caagactact ccacaccgtc atccgagtcc aacaacaacg agaaggagcg gaagctgccg 4921 gcacccagga aatactgtga ttcctgcgag gtttttggcc acgatacgag cgaatgtgcc 4981 gatgatgaaa cctattagtt agctctagtt aaattctatt atttccattt tactttgttt 5041 tagactctat agcataacca tattgcgaga tctatcagat gagatacttt tacctcagca 5101 gagcttcact caatcacaca aagaaatttc tctacttaaa attgtgatct tgcgttatgc 5161 acacatccat ggatagtagt ctattttaaa ttgtttttat ttattgaatg cgattcgtgg 5221 caaacacaca atcggttgtt ttcgtaattt ttgagtgtaa acatagtgta aaaaataaaa 5281 tcaagaacgt g //