Dbfetch
LOCUS NM_001103767 6552 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster protein kinase N, transcript variant G (Pkn), mRNA. ACCESSION NM_001103767 VERSION NM_001103767.2 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 6552) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 6552) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 6552) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 6552) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 6552) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 6552) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 6552) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 6552) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 6552) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 6552) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 6552) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 6552) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 6552) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 6552) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 6552) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 6552) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 6552) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 6552) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 6552) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 6552) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 6552) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 6552) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 6552) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 24 (bases 1 to 6552) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Dec 17, 2009 this sequence version replaced NM_001103767.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..6552 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="2R" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..6552 /gene="Pkn" /locus_tag="Dmel_CG2049" /gene_synonym="3-2; CG2049; CG2055; CG8; CT6637; CT6660; Dmel\CG2049; dPKN; Dpkn; DPKN; l(2)06736; l(2)45Ca; Pk45C; Pk?3; PKC-related; pkn; PKN; PRK2; v(2)rG232" /note="Protein kinase N" /map="45C1-45C1" /db_xref="FLYBASE:FBgn0020621" /db_xref="GeneID:35950" CDS 293..4798 /gene="Pkn" /locus_tag="Dmel_CG2049" /gene_synonym="3-2; CG2049; CG2055; CG8; CT6637; CT6660; Dmel\CG2049; dPKN; Dpkn; DPKN; l(2)06736; l(2)45Ca; Pk45C; Pk?3; PKC-related; pkn; PKN; PRK2; v(2)rG232" /EC_number="2.7.11.1" /note="CG2049 gene product from transcript CG2049-RG; CG2049-PG; Pkn-PG; protein kinase-like 45C; protein kinase related to protein kinase N; complementation group 8; protein kinase c related" /codon_start=1 /product="protein kinase N, isoform G" /protein_id="NP_001097237.1" /db_xref="FLYBASE:FBpp0111810" /db_xref="GeneID:35950" /db_xref="FLYBASE:FBgn0020621" /translation="MSKLVKRIRSMINPSSQRDREDTTSVSASEGFIARRKCHSLPRR SNRHSTARRSNSGLWNRLVTNVFGPEDSYDFDNEGDSGGAVFYTDSVNGSNYEISAEG EYIKHPVLYELSHKYGFTENLPESCMSIRLEEIKEAIRREIRKELKIKEGAEKLREVA KDRRSLSDVAVLVKKSKSKLAELKSELQELESQILLTSANTAVNSNGQESITACIDPN GGFLVSGAVGGLGGGNTALEGGAPATANDKVLASLEKQLQIEMKVKTGAENMIQSLGI GCDKKLLAEAHQMLADSKAKIEFLRLRIIKVKQNREQADRLKASRQMIDEHGQTIGGN NSSQPQSLETTLEERIEELRHRLRIEAAVVDGAKNVIRTLQTANRAPDKKALQEAHGR LSESSRKLDLLRYSLDLRRQELPADSPAAQQLKTELQIVQLSTSPAPVTYTSLQSGQA GILGGKPYQSVSSLGRCASVTGKLEVRLLGCQDLLEDVPGRSRRDKDNNSSPGDLRSF VKGVTSRSSSKSYSVKDETSIEIMAVIKLDNITVGQTSWKQCSQQAWDQRFSIDLDRS RELEIGVYWRDWRSLCAVKVLRLEEFIDDVRHGMALQLEPQGLLFAEVKFLNPMISQK PKLRRQRMIFNRQQAKNISRAKQMNINVATWGRLLKRNAPNHVHMGSAGSGSSLTGSS PMVVGGSRDSESPISRTPSSDALVEPEPYTPGEQAQNLEFDPDAGINEHVETPGEYPD PAASGLSGMRPLSMHMQGISVLPPESPPVATGAAGRPNTLSLQMPGASKGQVIQGGRT AAPTTAPPPPPVLKATSTTPILDQELQDALHEFDFLSDLDSRPTTLRRLLKEQKMALD AGALENLLLQQQQTEQQALQQRQRQEQLRLQQFQEAQRQAILDLCVKQREPAEQTSPT LANQTPTFPPLASNQIMPSLNARPCQSQSPNHNEFQLQPQPPHPAQKPTNPEPPSAVE QQLHRPVLILPPVVLLGGREEDRSVPPSPLVEYPEDDDEYLYRGSNENLGTRLHSSHS SSAGDRFCVEVIPQLGKLYVGSSQQQYAQQSSPIIQEPATPTIYGNSAAAGAPQFPQP AQRQEKQPPQQQPIYANQYELNVAKAAAAASVYSPSSSTTSNSNQQQQQQRRNVARGL QYRESGGLETGRAGKQPPNAGMLSMDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKA LKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDL MMHIHTDVFLEPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGL CKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDD EEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAFFRSI VWDDLLLRKVKPPFVPTINHLEDVSNFDEEFTSEKAQLTPPKEPRHLTEEEQLLFQDF SYTAEWC" ORIGIN 1 agtggctatc agacagaagc aatcgagaac cgcttaatga gaaagccaaa gaaacttgtt 61 gaactacaag aaaaagaagc acaagaaggc agaagaaccc ggagggggag gcaaaaaaca 121 ttttccagat aagcggcagt cggagtcgtg tgaataaaag cgtgtgtatt tgttttgtgg 181 gtcagcctgt tccagctaat taccgtgaac ttgtcagcgc acacaaaacg gctgtaaaat 241 gaccaaagtg aggtaataaa cacggcgaat taacgagaaa cccgagtgaa taatgtccaa 301 actggtgaag agaatccgca gcatgatcaa tccaagcagc cagcgggatc gcgaagatac 361 cacctcggta tccgcttcag agggcttcat tgctcgcagg aagtgccact cgctgccccg 421 aaggagcaat agacactcga ccgcccggcg atcaaacagt ggtctgtgga atcgactggt 481 caccaatgtc ttcggaccgg aagattcata tgactttgac aacgaaggcg acagtggtgg 541 tgccgtattt tacaccgatt cggtgaacgg ttcaaactat gagatatctg cagaaggcga 601 atacatcaag catcccgttc tgtacgagct cagtcacaaa tatggtttca cagagaatct 661 gccggagagc tgtatgtcca tacggctgga ggagatcaag gaggccattc ggcgagagat 721 ccgcaaggag ctgaagatca aagagggcgc cgagaagctc cgcgaggtgg ctaaagatcg 781 acgatccctc agcgatgtgg ccgttcttgt caagaagagc aaaagtaaac ttgccgagct 841 gaagtccgag ttgcaggagc tcgagagtca aatcctcctg acatcggcca acaccgccgt 901 caatagtaat ggacaagaat cgatcactgc ctgcattgat cccaatggcg gcttcttggt 961 cagcggtgca gttggtggct tgggcggcgg aaacacggct ctggagggcg gcgcaccggc 1021 cactgccaat gacaaagtgc tcgcctcgct ggagaagcag ctgcagatcg agatgaaggt 1081 gaagaccggg gcggaaaaca tgatccagtc gctgggcatc ggatgcgaca agaagctgct 1141 ggcggaagcc caccagatgc tggccgactc gaaggccaag attgagtttt tgcgcctgcg 1201 catcatcaag gtgaaacaga accgcgagca ggccgatcgc ctcaaggcct cgcgccagat 1261 gatcgacgag catggccaga cgatcggcgg gaacaacagc agccagccgc agagcctgga 1321 gacgacgctg gaggagcgaa tcgaggagct ccgccatcga ctgcgaatcg aggcagccgt 1381 cgtcgatgga gccaagaatg ttatacgcac gctgcagacg gcgaataggg caccggacaa 1441 gaaggctttg caggaggccc atggacgttt gtcggaatcg tcgcgaaaac tagatctctt 1501 gcgctactcc ttggatttac gacgccagga gctgcccgcc gattcgcccg ccgcccagca 1561 attaaaaacg gagctgcaga tcgtccagct atcgacctcc ccagctccgg tcacctacac 1621 gtcactgcag tccggacaag cgggcatact cggcggaaag ccgtaccagt cggtatcctc 1681 gcttggacgc tgtgccagtg tcaccggaaa actggaggtt cgcttgctgg gctgtcaaga 1741 tttgctggaa gatgtgcccg gtagatcgag gagggacaag gacaacaact caagtccggg 1801 tgatttacga agcttcgtca agggcgtcac gtcgcgcagc agttcaaaga gctattcggt 1861 aaaggatgag acgtccattg agatcatggc ggtcatcaag ctggacaata tcaccgttgg 1921 ccagacatcg tggaagcaat gctcgcagca ggcctgggat cagcgcttct ccatcgatct 1981 agaccggtcg cgcgaactgg agattggagt ttactggcgc gactggcgat ccctgtgcgc 2041 cgtaaaggtg ctgcgccttg aagagttcat cgacgatgta cgacatggca tggcattgca 2101 gctggagcca caaggtctgc tatttgcgga ggtcaagttc ttgaacccca tgatttcaca 2161 gaagccaaag ctgaggcgcc agcgtatgat cttcaacagg cagcaagcga agaacatctc 2221 gcgggccaag cagatgaaca ttaatgtggc cacatggggc cgcctgctta agcggaatgc 2281 tcctaaccat gtgcacatgg gatcggcagg atcaggatct tctctaaccg gtagctcgcc 2341 tatggtggtt ggtgggtctc gcgactctga gtctccgatt tcgaggactc cctcatccga 2401 cgcactggtg gaaccggagc cctacacgcc cggagagcag gcacagaact tggaattcga 2461 tcccgatgca ggaattaatg aacacgtgga gacgccaggt gaatacccgg atccggcggc 2521 cagtggtctg agcggaatgc gacccctgtc catgcacatg cagggaatta gtgtgctgcc 2581 cccggaatcg ccacccgtgg ccaccggagc agctggtcgg cccaatacgc tcagcttaca 2641 gatgccgggt gccagtaaag gacaggtgat ccaaggcgga cggactgcgg cgcctacaac 2701 ggcgccaccg ccaccacctg tgctcaaggc gacatccacc actccgatat tggatcagga 2761 gctgcaggat gccctgcacg aattcgattt cctgtcggac ctggactcac gtcccaccac 2821 gctgcgtcgc ctgctgaagg agcagaagat ggcgctggat gccggcgcgc tggagaatct 2881 gctgctgcag cagcaacaga ctgagcagca ggcactgcag cagcgccagc gccaggagca 2941 gctgcgtctg cagcagtttc aggaggcgca gcgccaggcg atcctggacc tgtgcgtgaa 3001 acagagagag cccgcggagc agacatcacc cacccttgcc aaccaaacgc cgacgttccc 3061 accgcttgcc agcaatcaga tcatgccaag cttaaatgcc cgcccttgcc aaagccaaag 3121 cccaaaccac aacgaatttc agttgcagcc gcagccacca catcccgccc agaaaccgac 3181 gaatcccgaa ccaccgtccg ctgtggaaca gcagctgcac cgtccggtcc taatcctgcc 3241 gcccgtggtg ctcctgggtg gtcgggagga ggaccgttcg gtgccaccat cgccactagt 3301 cgagtatccc gaggacgacg acgagtatct gtatcgtggt agcaacgaaa acctgggcac 3361 caggctgcac tccagccaca gttccagtgc cggcgatcgt ttctgtgtgg aggttatacc 3421 acagttgggg aagctttacg tgggcagtag ccagcagcag tatgcgcagc agtcatcgcc 3481 catcatccag gagccagcta ctcctactat ttacggaaac agcgccgcag ccggagcgcc 3541 gcagttcccg cagcccgccc aaaggcaaga gaagcagcct ccgcagcagc agcccatcta 3601 cgctaaccag tatgagctga atgtggccaa ggcggcagct gcagcatctg tttactcacc 3661 cagctcctcc accaccagca actccaatca acagcagcag cagcagcgcc ggaatgtggc 3721 ccgtggactg cagtatcgtg aatctggagg actcgagact ggacgtgctg gcaagcagcc 3781 acccaatgcg ggcatgttgt caatggacaa cttccgtttg ctaagcgttc ttggtcgcgg 3841 ccactttggc aaggtgattc tgtcccaatt gcgaagcaac aaccagtact acgctattaa 3901 ggcactgaag aagggagaca tcattgcccg cgacgaagtg gagtccctgc ttagcgaaaa 3961 gcgcatcttc gaggtggcca acgccatgcg ccatccgttc ttagttaact tgtattcgtg 4021 cttccagact gagcaacacg tatgctttgt gatggaatac gctgctggcg gagatttgat 4081 gatgcacatc cacacggacg tgttcctaga gccgagagcc gttttctacg ccgcttgtgt 4141 ggttctgggc ctgcagtacc tgcacgagaa caagatcatc taccgggacc tgaagctgga 4201 caatttgctt ttggacacgg aaggatatgt gaaaattgcg gactttggtt tgtgcaagga 4261 gggcatgggc tttggtgatc gcacgggcac tttctgtggt acgcccgagt ttctggcacc 4321 ggaagtgctc acggaaactt cctacacacg agctgtggat tggtggggct tgggtgtgtt 4381 gatctttgag atgttggttg gtgagtcccc attccctggt gacgatgagg aggaagtatt 4441 cgattcaatt gtcaacgatg aggtgcgcta tccgcgcttc ctatcgctgg aggccatagc 4501 cgtgatgcgt aggcttttgc gcaagaatcc agagagacgt ctgggatctt cggaacggga 4561 tgcggaggat gttaagaaac aggcattctt ccggtcaatt gtgtgggatg acctgctcct 4621 gcgaaaggtt aaaccaccat ttgtgccgac aattaaccac ttggaggatg tgtcaaactt 4681 tgacgaggag ttcacgtcgg agaaggctca gcttacgcca ccgaaggagc cgcgacactt 4741 gaccgaggag gagcagttgc tcttccagga cttttcatac acggccgaat ggtgttagaa 4801 gctcattctt agttcaagga tttactaacg ggcctagccc gatccttata gcctatggcc 4861 tgcttttgct tttacttgtg tacgaaattg gtttcgagta attttacttg gcttagtagt 4921 cgatgtgagt tcaatattta tacatgaaga cagcatgata atacagatac aggacatata 4981 tatttataaa ctatatctat atagaaaata catctactaa cgagagaact tttgattgtt 5041 gctcactggc cgagagacca acacaaacca aaatacctag ttgtccatgt tgtggaaaag 5101 caagcatttg tcaatcatcc atgcaaccgg tttagcatac agtgtaccca gaaatcatcc 5161 cacattgtcg ttgcattgta cagcatatag agttgtttcc ttttccaaac acgagaacgc 5221 attgaatagt ctgacaaacc ctaggaaagc cttatacgcc aagttgtagt tttggaaacc 5281 gttttttaag accggataca aatagatttt atagatgaga agtgtatgtc tacaccccag 5341 agcagtcatt gcaacctatt ttcataatca acatacaaga acaaagatat attttataca 5401 tatattgcat gcacatccca ggaatcgtct tgctaaacga gctcatcttc tatacgacat 5461 acaaacatac atatttatct agtaaagtga gagaaagtga aatatttaca gttttaacat 5521 gtaagccctg taaattgcct tttgccgcgt tttatcaact ccccagccca ttgcccgagt 5581 tgtgttataa tttaaacata ttttttacgt catatacaca cgcaaacatt tgttatttat 5641 tattattata actattatac aagaaaactg tattgctttg agcattttta ttcgacgcta 5701 gatcgatgat tgtaaacaat ttgttttgca tgcgcggtgt gctttaaacc agatatgagg 5761 atcagaaaac aaataaccgc tcgacgggat agaatttgga aattccgttg atggatggca 5821 tgcaatcgga ttgttgtact tctaagatct atgttgtatt taatgtaact tttagttcga 5881 tttaagcttg taataatcga ttattgaaac gtagtctaag ctatcattat gtgaagataa 5941 ttattgataa ttacaattat gataacgatt ttgcacacct catgcgaatc gaaacgagta 6001 taaacaatgc agatcttcta ttgtcatttt tattatgatt atgctcacaa cttgcggcta 6061 taatcatcga tttaatttta aatctgtaaa gtcggattgg tgcacatcca atcacattgt 6121 ttagtttcaa gttgcgactg taatttatat ttatgatatg attttaaata aatgtatcta 6181 tcgctattat ttaactgctg tttttgtcga ctggttttcg ctgagacctt cgctcatttg 6241 gtaatacaaa atattggcgg tattgtccac aacggctaaa aatatgttgc tgatagggaa 6301 taaagtggtt aaaaacataa atattatttt cataacattt aatacgcacc gttttttaag 6361 ctttttgtgt aaagatttta caattctaaa gtcgattgcc tttgtgtgca gcacaggaat 6421 ataaacatca tcatttttca tcaaataaaa cactttcaga tttggatcat agttgggttg 6481 gaattcggcg ctttcttcct ctaatgcata ataataaata ttaaattgag aattaaatat 6541 gcttgaatta cc //