Dbfetch
LOCUS NM_001103523 5683 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster clathrin heavy chain, transcript variant E (Chc), mRNA. ACCESSION NM_001103523 VERSION NM_001103523.2 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 5683) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 5683) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 5683) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 5683) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 5683) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 5683) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 5683) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 5683) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 5683) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 5683) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 5683) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 5683) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 5683) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 5683) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 5683) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 5683) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 5683) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 5683) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 5683) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 5683) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 5683) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 5683) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 5683) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jul 15, 2014 this sequence version replaced NM_001103523.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..5683 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..5683 /gene="Chc" /locus_tag="Dmel_CG9012" /gene_synonym="CG9012; chc; CHC; chc1; Cla; Clh; CLH; D-Chc; dCHC; Dmel\CG9012; l(1)13Fb; l(1)G0438; l(1)VI" /note="Clathrin heavy chain" /map="13F5-13F7" /db_xref="FLYBASE:FBgn0000319" /db_xref="GeneID:32537" CDS 361..5397 /gene="Chc" /locus_tag="Dmel_CG9012" /gene_synonym="CG9012; chc; CHC; chc1; Cla; Clh; CLH; D-Chc; dCHC; Dmel\CG9012; l(1)13Fb; l(1)G0438; l(1)VI" /note="CG9012 gene product from transcript CG9012-RE; CG9012-PE; Chc-PE; clathrin heavy-chain; clathrin heavy chain; clathrin hc" /codon_start=1 /product="clathrin heavy chain, isoform E" /protein_id="NP_001096993.1" /db_xref="FLYBASE:FBpp0111709" /db_xref="GeneID:32537" /db_xref="FLYBASE:FBgn0000319" /translation="MTQPLPIRFQEHLQLTNVGINANSFSFSTLTMESDKFICVREKV NDTAQVVIIDMNDATNPTRRPISADSAIMNPASKVIALKAQKTLQIFNIEMKSKMKAH TMNEDVVFWKWISLNTLALVTETSVFHWSMEGDSMPQKMFDRHSSLNGCQIINYRCNA SQQWLLLVGISALPSRVAGAMQLYSVERKVSQAIEGHAASFATFKIDANKEPTTLFCF AVRTATGGKLHIIEVGAPPNGNQPFAKKAVDVFFPPEAQNDFPVAMQVSAKYDTIYLI TKYGYIHLYDMETATCIYMNRISADTIFVTAPHEASGGIIGVNRKGQVLSVTVDEEQI IPYINTVLQNPDLALRMAVRNNLAGAEDLFVRKFNKLFTAGQYAEAAKVAALAPKAIL RTPQTIQRFQQVQTPAGSTTPPLLQYFGILLDQGKLNKFESLELCRPVLLQGKKQLCE KWLKEEKLECSEELGDLVKASDLTLALSIYLRANVPNKVIQCFAETGQFQKIVLYAKK VNYTPDYVFLLRSVMRSNPEQGAGFASMLVAEEEPLADINQIVDIFMEHSMVQQCTAF LLDALKHNRPAEGALQTRLLEMNLMSAPQVADAILGNAMFTHYDRAHIAQLCEKAGLL QRALEHYTDLYDIKRAVVHTHMLNAEWLVSFFGTLSVEDSLECLKAMLTANLRQNLQI CVQIATKYHEQLTNKALIDLFEGFKSYDGLFYFLSSIVNFSQDPEVHFKYIQAACKTN QIKEVERICRESNCYNPERVKNFLKEAKLTDQLPLIIVCDRFDFVHDLVLYLYRNNLQ KYIEIYVQKVNPSRLPVVVGGLLDVDCSEDIIKNLILVVKGQFSTDELVEEVEKRNRL KLLLPWLESRVHEGCVEPATHNALAKIYIDSNNNPERYLKENQYYDSRVVGRYCEKRD PHLACVAYERGLCDRELIAVCNENSLFKSEARYLVGRRDAELWAEVLSESNPYKRQLI DQVVQTALSETQDPDDISVTVKAFMTADLPNELIELLEKIILDSSVFSDHRNLQNLLI LTAIKADRTRVMDYINRLENYDAPDIANIAISNQLYEEAFAIFKKFDVNTSAIQVLID QVNNLERANEFAERCNEPAVWSQLAKAQLQQGLVKEAIDSYIKADDPSAYVDVVDVAS KVESWDDLVRYLQMARKKARESYIESELIYAYARTGRLADLEEFISGPNHADIQKIGN RCFSDGMYDAAKLLYNNVSNFARLAITLVYLKEFQGAVDSARKANSTRTWKEVCFACV DAEEFRLAQMCGLHIVVHADELEDLINYYQNRGYFDELIALLESALGLERAHMGMFTE LAILYSKFKPSKMREHLELFWSRVNIPKVLRAAESAHLWSELVFLYDKYEEYDNAVLA MMAHPTEAWREGHFKDIITKVANIELYYKAIEFYLDFKPLLLNDMLLVLAPRMDHTRA VSYFSKTGYLPLVKPYLRSVQSLNNKAINEALNGLLIDEEDYQGLRNSIDGFDNFDNI ALAQKLEKHELTEFRRIAAYLYKGNNRWKQSVELCKKDKLYKDAMEYAAESCKQDIAE ELLGWFLERDAYDCFAACLYQCYDLLRPDVILELAWKHKIVDFAMPYLIQVLREYTTK VDKLELNEAQREKEDDSTEHKNIIQMEPQLMITAGPAMGIPPQYAQNYPPGAATVTAA GGRNMGYPYL" ORIGIN 1 atatcggcat taattgtata actttcacac ctctaccttg tcttgcagtc agtatttagt 61 caaacaaaag aaaaataaac tacatttgtt agagcttgat aagagctcag tttgtcttca 121 gtgtgtgtgc ccgtcatcta gcaacaaacc gacctaaacg ttccaatgga aaccgaatct 181 taaaccagaa accgactaaa ctcgaacgca attaaacaac aataaatcct cgaaacaaat 241 caaatacaaa ctgttaccaa gtgtgcaatt caagaaaaca tcgtattggc attgttttcg 301 caaagataca tttacgttgt aaaggtctgt caataactag acctcactgt agtagtaaag 361 atgacgcaac cactgcccat ccgctttcag gagcatttac agctcacaaa tgtcgggatc 421 aacgccaatt cattttcatt cagcacgctc acgatggaat cggataagtt tatttgcgtg 481 cgggagaagg tgaatgatac cgcccaagtg gtcatcattg acatgaacga tgccaccaat 541 cccacgcggc gtcccatctc agcggattcg gctatcatga atccagctag caaggtcatt 601 gcgctcaaag cgcaaaagac gttgcagatc ttcaacattg agatgaagtc gaagatgaag 661 gcgcatacca tgaacgagga tgtggtgttc tggaagtgga tctccctcaa tacgctagct 721 ctggtcacag aaacgagtgt gttccattgg tccatggagg gcgattcgat gccgcaaaag 781 atgtttgacc ggcattcatc gctgaacggt tgtcaaatca tcaactaccg ctgcaatgcc 841 tcccagcagt ggctactctt ggtcggcatt tcggcactgc caagtcgcgt tgccggtgcc 901 atgcagttgt attcggtgga gcgtaaggtg tcccaggcga tcgaggggca tgcggccagt 961 tttgccacgt ttaaaatcga tgccaacaag gagccgacca cgctgttctg ctttgcagtt 1021 cgtacggcca ctgggggcaa gcttcatatt atcgaagttg gtgctccgcc gaacggcaat 1081 cagccgtttg ccaagaaggc tgtcgatgtc ttctttccgc cggaagcaca aaatgatttc 1141 cctgtggcta tgcaagtctc tgccaagtac gacaccatct acttgataac caagtatgga 1201 tacatacatc tgtatgacat ggagacggcc acgtgcatat acatgaatcg tatatcggcc 1261 gatacgatct ttgttaccgc accgcatgag gcaagtggtg gcatcattgg cgtcaatcgc 1321 aagggacagg tcctctccgt gaccgtcgac gaggagcaga tcattcccta catcaacacc 1381 gttctgcaga atcccgattt ggcccttcgc atggccgtgc gcaacaattt ggctggtgcc 1441 gaagatctct ttgtgcgaaa gttcaacaag ctctttacag ccggccagta tgctgaagcg 1501 gctaaagttg ctgccctggc acccaaggcc attctgcgta cgccacagac gatccagcgt 1561 ttccaacagg tgcagacacc agctggctcc acgactccgc cgctgctgca atactttggc 1621 attctcctcg accagggcaa gctgaacaag ttcgagtctc tcgagctgtg ccgtcccgtc 1681 ttgctgcagg gcaagaagca gctgtgcgag aagtggctga aggaggagaa gttggaatgc 1741 agcgaggagt tgggtgatct ggtcaaggcc tccgatctta cacttgccct gtccatctat 1801 ctgcgcgcaa atgtgcccaa caaggttatc caatgctttg ctgagactgg gcagttccag 1861 aagattgtac tctacgccaa gaaggtcaac tatacgcccg attacgtgtt cctgctgcgc 1921 tccgtgatgc gaagcaaccc ggagcaagga gctggtttcg cctctatgtt ggtggccgag 1981 gaagagccac tggcggacat caatcagatt gtggacatct tcatggagca ctccatggtg 2041 cagcagtgca ctgcattcct gctggacgcc ctcaagcata accgtcccgc cgagggtgcc 2101 ctccagacgc gcctgctgga aatgaatctg atgtctgctc cgcaggtggc cgacgccatc 2161 ctgggcaatg ctatgttcac ccactacgat cgggcccaca ttgcccagct gtgcgagaag 2221 gctggactgc tccagcgcgc cctcgagcac tacacggatc tgtatgacat taagcgggcc 2281 gttgtgcaca cgcacatgct gaatgccgaa tggctggtca gtttctttgg cacgctgtcg 2341 gtggaggact cgctggaatg tctgaaggca atgcttacgg cgaatttgcg ccagaacttg 2401 cagatctgtg tgcagattgc caccaagtat cacgaacagc tgaccaacaa ggcactgatt 2461 gatctgttcg aaggtttcaa gagctacgac ggactgttct acttcctgag cagcattgtc 2521 aacttctcac aggatcccga agtgcacttc aaatacattc aggcggcatg caagactaat 2581 cagattaagg aggtggagcg aatttgccgt gaatcaaact gctacaatcc cgaacgggtg 2641 aagaacttct tgaaggaggc caagctgacg gatcagctac cattaattat tgtttgtgat 2701 cgttttgatt tcgtgcacga cttggtgctt tacctgtatc gtaacaatct gcagaagtac 2761 attgagatct atgtgcagaa agtgaatcca tcccgcttgc cagtggtagt gggtggtctt 2821 cttgatgttg attgcagtga ggatataatt aaaaatctaa ttctcgtggt caagggacaa 2881 ttctcaaccg acgaactggt cgaggaggtc gagaagcgca accgtctcaa gcttctcctt 2941 ccctggctgg agtcccgagt tcacgagggc tgcgtcgagc cagccaccca caacgcgttg 3001 gccaagatct acattgactc gaacaacaat cccgagagat atcttaagga gaatcagtac 3061 tacgatagcc gtgtggtcgg tcgctactgc gagaagcggg atccccattt ggcgtgtgtc 3121 gcctacgagc gtggattgtg cgatcgcgag ctgatcgccg tttgtaacga gaattctctg 3181 ttcaagagcg aagcacgcta cttggttggt cgccgcgacg ccgaactctg ggccgaggtc 3241 ctttcggaga gcaatccata caagcgccag ttgatcgatc aggtggtaca gaccgctttg 3301 tccgagaccc aggatcccga tgacatctct gtaacggtca aagcattcat gaccgccgat 3361 ttgcccaatg agctgatcga acttctcgag aagattattc tggactcgtc cgtctttagc 3421 gaccatcgca atctgcaaaa cttgctcatt ctcacagcca tcaaggctga tcgcacccga 3481 gtcatggact acattaaccg gctggagaac tacgatgcac cggacatcgc gaacattgcg 3541 atcagtaatc agttgtacga agaagccttc gccatcttca agaagttcga tgtgaacaca 3601 tcggccattc aggtgctcat cgatcaagtg aacaacctgg agcgggctaa cgagttcgcc 3661 gagcggtgca atgagccggc cgtttggtcg cagctggcca aggcccaact gcagcagggt 3721 ctggtcaagg aggctatcga ctcgtacatc aaggctgatg atccgagcgc ttacgtcgat 3781 gtcgtcgatg tggccagcaa ggtggagtct tgggatgacc tcgttcgcta tctgcaaatg 3841 gcacgcaaga aggcgcgcga atcttacatc gagagcgaat tgatctatgc ctatgcgcgc 3901 actggacgtc tggccgatct ggaggagttc atttcgggtc ccaaccatgc cgatatccag 3961 aagattggca accgttgctt cagcgacggc atgtacgatg cagcgaagct actgtacaac 4021 aatgtgagca actttgcccg tctggccatc actttggtct acctgaagga gttccaaggg 4081 gccgtggact cggcgcggaa agccaactca acgcgcacat ggaaggaggt gtgcttcgcc 4141 tgcgtggacg ccgaggagtt taggctagct cagatgtgcg gcctgcacat tgtggtgcat 4201 gccgatgagc tagaggatct gattaactac tatcaaaacc gtggatactt cgatgaattg 4261 attgcgctac tcgagtcggc tttggggctg gaacgtgcgc acatgggaat gttcaccgaa 4321 ttagctatac tttattcaaa attcaaacct tccaaaatgc gcgaacactt ggagctgttc 4381 tggtctcgcg ttaacattcc aaaagttctg cgtgccgctg aatcggctca cttgtggtcg 4441 gagctggtgt tcctgtacga taagtacgag gagtacgata acgccgtcct ggccatgatg 4501 gctcatccca cggaggcgtg gcgcgagggg cactttaagg acattatcac caaggtagcc 4561 aacattgagc tgtactacaa ggctatcgaa ttctatttgg acttcaagcc gctgctgttg 4621 aacgacatgc tgctcgtgct ggcacccagg atggatcaca ctcgtgctgt tagttacttc 4681 tccaaaaccg gctatttgcc actcgtcaag ccttatctgc gttcagtcca atctctcaat 4741 aacaaggcaa tcaacgaagc cctgaacgga ctcttaatcg acgaggagga ctaccagggt 4801 ctgcgcaatt cgatcgatgg atttgataac tttgacaaca ttgcgttggc acagaaactc 4861 gaaaagcacg aacttaccga attccgtagg attgccgcct acttgtacaa gggaaataat 4921 cgctggaaac agagcgttga gctctgcaaa aaggataaac tctacaagga tgctatggag 4981 tacgccgccg aatcttgcaa gcaagatatt gccgaagagt tgttgggttg gttcctagaa 5041 cgtgacgctt acgattgttt tgcagcttgt ctttatcagt gttacgactt gctgcgccct 5101 gatgttatct tggagttggc ctggaaacac aaaatcgttg actttgccat gccctatttg 5161 attcaggttc tgcgcgaata cacaacaaag gtggacaaac tggagttgaa cgaggctcag 5221 cgcgagaagg aggacgattc cactgagcac aaaaacatta ttcagatgga gccacaactg 5281 atgatcaccg ctggcccagc aatgggcatt cctccacaat atgcacagaa ttatccacct 5341 ggtgcagcaa cggtaacggc ggcaggagga cgcaacatgg gctatcccta cttgtaggac 5401 ttgcgcccga taatgagatc atcaaaacaa ctttaaaaac aaatgtatca gcattaaagg 5461 aataccaata aaataagaaa aataatctat taattgcatg tgcgccaaaa attaccaaaa 5521 cgaaacaaca cagtaaacat aactttgaac atcattatat taaagcaatg caattaacaa 5581 tccaattttt ggtttgtttg tagacagtta aaaattgatt atatgttttg ataattacag 5641 cactctttat tcaaatataa cagaatatat tactttttat cat //