Dbfetch
LOCUS NM_001103486 7249 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster discs large 1 (dlg1), transcript variant L, mRNA. ACCESSION NM_001103486 VERSION NM_001103486.3 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 7249) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 7249) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 7249) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 7249) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 7249) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 7249) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 7249) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 7249) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 7249) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 7249) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 7249) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 7249) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 7249) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 7249) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 7249) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 7249) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 7249) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 7249) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 7249) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 7249) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 7249) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 7249) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 7249) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jan 16, 2013 this sequence version replaced NM_001103486.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..7249 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..7249 /gene="dlg1" /locus_tag="Dmel_CG1725" /gene_synonym="11; anon-EST:Posey93; anon-WO03040301.258; anon-WO03040301.260; anon-WO03040301.268; CG1725; CG1730; CPD; d. lg.-1; Discs Large; Discs-large; dlg; Dlg; DLG; dlg-1; dlg-A; Dlg-A; DLG-A; Dlg1; DLG1; dlgA; DlgA; dlgS97; DlgS97; Dmel\CG1725; Drodlg; l(1)10Bf; l(1)bwn; l(1)d.lg-1; l(1)d.lg.-1; l(1)discs large; l(1)dlg; l(1)dlg-1; l(1)dlg1; l(1)G0276; l(1)G0342; l(1)G0456; l(1)G19; l(1)l.pr.-2; l(1)L11; l(1)lpr-2; misb; PSD-95; PSD95; SAP97" /note="discs large 1" /map="10B6-10B10" /db_xref="FLYBASE:FBgn0001624" /db_xref="GeneID:32083" CDS 811..3651 /gene="dlg1" /locus_tag="Dmel_CG1725" /gene_synonym="11; anon-EST:Posey93; anon-WO03040301.258; anon-WO03040301.260; anon-WO03040301.268; CG1725; CG1730; CPD; d. lg.-1; Discs Large; Discs-large; dlg; Dlg; DLG; dlg-1; dlg-A; Dlg-A; DLG-A; Dlg1; DLG1; dlgA; DlgA; dlgS97; DlgS97; Dmel\CG1725; Drodlg; l(1)10Bf; l(1)bwn; l(1)d.lg-1; l(1)d.lg.-1; l(1)discs large; l(1)dlg; l(1)dlg-1; l(1)dlg1; l(1)G0276; l(1)G0342; l(1)G0456; l(1)G19; l(1)l.pr.-2; l(1)L11; l(1)lpr-2; misb; PSD-95; PSD95; SAP97" /EC_number="2.7.4.8" /note="CG1725 gene product from transcript CG1725-RL; CG1725-PL; dlg1-PL; discslarge; disc large; lethal(1)discs-large; lethal(2)discs large; disk large; Disc-Large; disclarge; Discs-large; discs large 1; lethal(1)benign wing imaginal disc neoplasm; Discs-large 1; lethal(1)discs large" /codon_start=1 /product="discs large 1, isoform L" /protein_id="NP_001096956.1" /db_xref="FLYBASE:FBpp0111725" /db_xref="GeneID:32083" /db_xref="FLYBASE:FBgn0001624" /translation="MPVKKQEAHRALELLEDYHARLSEPQDRALRIAIERVIRIFKSR LFQALLDIQEFYELTLLDDSKSIQQKTAETLQIATKWEKDGQAVKIADNQRMRIESDT ENAKEPTVEQQQKQQQAQQRSSRSPQQQNPQQQQGSKSRSGSQTLHKASSTKVNGDDS WLYEDIQLERGNSGLGFSIAGGTDNPHIGTDTSIYITKLISGGAAAADGRLSINDIIV SVNDVSVVDVPHASAVDALKKAGNVVKLHVKRKRGTATTPAAGSAAGDARDSAASGPK VIEIDLVKGGKGLGFSIAGGIGNQHIPGDNGIYVTKLMDGGAAQVDGRLSIGDKLIAV RTNGSEKNLENVTHELAVATLKSITDKVTLIIGKTQHLTTSASGGGGGGLSSGQQLSQ SQSQLATSQSQSQVHQQQHATPMVNSQSTEPGSRYASTNVLAAVPPGTPRAVSTEDIT REPRTITIQKGPQGLGFNIVGGEDGQGIYVSFILAGGPADLGSELKRGDQLLSVNNVN LTHATHEEAAQALKTSGGVVTLLAQYRPEEYNRFEARIQELKQQAALGAGGSGTLLRT TQKRSLYVRALFDYDPNRDDGLPSRGLPFKHGDILHVTNASDDEWWQARRVLGDNEDE QIGIVPSKRRWERKMRARDRSVKFQGHAAANNNLDKQSTLDRKKKNFTFSRKFPFMKS RDEKNEDGSDQEPFMLCYTQDDANAEGGEIIYRVELPDMEQITLIYLENNDADYPSEE NVLSYEAVQRLSINYTRPVIILGPLKDRINDDLISEYPDKFGSCVPHTTRPKREYEVD GRDYHFVSSREQMERDIQNHLFIEAGQYNDNLYGTSVASVREVAEKGKHCILDVSGNA IKRLQVAQLYPVAVFIKPKSVDSVMEMNRRMTEEQAKKTYERAIKMEQEFGEYFTGVV QGDTIEEIYSKVKSMIWSQSGPTIWVPSKESL" ORIGIN 1 gatcccaact agaactagtg ttcccgtgag cagagcagaa aaccgtaata tatattctcc 61 aacgtgctgc cgctacttat ttatattaaa cataaaatgc ccgaaggctg tgccaaacgc 121 atgtcctttt tgccaatggt gaatgcaata tagaatcaaa tcaagtgaac gcgaagtaag 181 caaataaacg atctgagttt ttttttgtgt tggtgttgtt gtgttgtgac gaggaaagta 241 cgacatttcg atgatagtcg cattgcaata taaagtgcaa cataaatgct atagaaccga 301 atgtgaatgt gaggagccat tgagctgtga aatgtgaaaa tcgcaaagaa atcgagagaa 361 aacgcacacg tcaatgtaac cacaaagctg ccccaagaaa acgaaaagta aaatatataa 421 agaaattaaa aaataaacta gcaaactgaa agcgcaaaat taaaaaaaaa acaacaaatc 481 tcgaactttg ttcgaaagcc aaagtatcta acaaaacaat atttgtacat aaaacaccat 541 cgaatagtat atatatatat atacatatat atcagatata tatacagatg tgctggcgaa 601 actaaaagga ggagaactca aggaaaagcc aaagcgattt ttccgcacat ttccactcga 661 aagcgactcc agtaaattct caaaattgcg acccacgctt ttcccagttc ggcggcgttg 721 aaccacaatc aaagctgctg caccaccgcc atttccgctg ccatttccac cagcaccacc 781 ataaatagta gcagaaacac cgctcacaga atgccagtga aaaagcaaga agctcatcgg 841 gctctcgagc tgctcgagga ctaccacgcg agactttcgg agccgcagga tcgggcgctg 901 cgtattgcaa tcgaacgcgt tatacgcata tttaaatctc gcttgtttca agcgctgtta 961 gatatacaag aattctatga attgacatta ttggatgact cgaagagcat acaacaaaag 1021 acagcggaga ccttgcaaat tgcaaccaaa tgggaaaagg atggccaggc agtcaaaata 1081 gctgataatc agcgcatgcg catcgaatcg gacacggaaa atgccaagga gccaactgtc 1141 gagcagcagc aaaagcagca gcaagcgcag cagcgcagtt cccgctcccc gcagcagcag 1201 aatccgcagc agcagcaggg atccaaatcg aggagcgggt cccagactct ccataaggca 1261 tcgtccacaa aggtgaatgg cgatgatagc tggttatacg aggacattca gctggagcgc 1321 ggcaactccg gattgggctt ttccattgcc ggcggtacgg ataatccgca catcggcacc 1381 gacacctcca tctacatcac caagctcatt tccggtggag cagctgccgc cgatggacgt 1441 ctgagcatca acgatatcat cgtatcggtg aacgatgtgt ccgtggtgga tgtgccacat 1501 gcctccgccg tggatgccct caagaaggcg ggcaatgttg ttaagctgca tgtgaagcga 1561 aaacgtggaa cggccaccac cccggcagcg ggatcggcgg caggagatgc tcgggatagt 1621 gcggccagcg gaccgaaggt catcgaaatc gatctggtca agggcggcaa gggactgggc 1681 ttctcaattg ccggcggcat tggcaaccag cacatccccg gcgacaatgg catctatgtg 1741 accaagttga tggacggcgg agcagcgcag gtggacggac gtctctccat cggagataag 1801 ctgattgcag tgcgcaccaa cgggagcgag aagaacctgg agaacgtaac gcacgaactg 1861 gcggtggcca cgttgaaatc gatcaccgac aaggtgacgc tgatcattgg aaagacacag 1921 catctgacca ccagtgcgtc cggcggcgga ggaggaggcc tttcatccgg acaacaattg 1981 tcgcagtccc aatcgcagtt ggccaccagc cagagccaaa gtcaggtgca tcagcagcag 2041 catgcgacgc cgatggtcaa ttcgcagtcg acagagcccg ggtcgcgata cgcctctaca 2101 aatgtcctag ccgccgttcc accaggaact ccacgcgctg tcagcaccga ggatataacc 2161 agagaaccgc gcaccatcac catccagaag ggaccgcagg gcctgggctt caatatcgtt 2221 ggcggcgagg atggccaggg tatctatgtg tccttcatcc tggccggcgg cccagcggat 2281 ctcgggtcgg agttgaagcg tggcgaccag ctgctcagcg tgaacaatgt caatctcacg 2341 cacgccaccc acgaagaggc agcccaggcg ctcaagactt ctggcggtgt ggtgaccctg 2401 ttggcgcagt accgcccaga ggagtacaat cgcttcgagg cacgcattca agagttgaaa 2461 caacaggctg ccctcggtgc cggcggatcg ggaacgctgc tgcgcaccac gcaaaagcga 2521 tcgctgtatg tgcgcgccct gtttgactac gatccgaatc gggatgatgg attgccctcg 2581 cgaggattgc cctttaagca cggcgatatc ctgcacgtga ccaatgcctc cgacgatgaa 2641 tggtggcagg cacgacgagt tctcggcgac aacgaggacg agcaaatcgg tattgtacca 2701 tcgaaaaggc gttgggagcg caaaatgcga gctagggacc gcagcgttaa gttccaggga 2761 catgcggcag ctaataataa tctggataag caatcgacat tggatcgaaa gaaaaagaat 2821 ttcacattct cgcgcaaatt tccgtttatg aagagtcgcg atgagaagaa tgaagatggc 2881 agcgaccaag agccctttat gctttgctac acacaagacg atgccaatgc tgaaggaggc 2941 gagattatct acagggtgga gttacccgat atggagcaga taactctgat ctacttggag 3001 aataatgatg ctgactatcc ttccgaggag aacgtgttgt cctacgaggc cgtacagcgt 3061 ttgtccatca actacacgcg cccggtgatt attctgggac ccctgaagga tcgcatcaac 3121 gatgacctta tatcagagta tcccgacaag ttcggctctt gtgtgccaca caccacccga 3181 cccaagcgag agtacgaggt ggatggtagg gactaccact ttgtatcctc tcgcgagcaa 3241 atggaacggg atattcagaa tcatctgttc atcgaggcgg gacagtataa cgacaatctg 3301 tacggcacat cggtggccag cgtgcgcgaa gtggccgaga agggtaaaca ctgcatcctg 3361 gacgtgtccg ggaacgccat caagcgactc caagttgccc agctgtatcc cgtcgccgtg 3421 ttcatcaagc ccaagtcggt ggattcagtg atggaaatga atcgtcgcat gacggaggag 3481 caggccaaga agacttacga gcgggcgatt aaaatggagc aagaattcgg cgaatacttt 3541 acgggcgttg tccaaggcga taccatcgag gagatttaca gcaaagtgaa atcgatgatt 3601 tggtcccagt cgggaccaac catttgggta ccttccaagg aatctctatg accaacagcc 3661 accacaactt ggacactgcc gcctcgagtt cgatgtcgac cagtctcgag aacaacaata 3721 ggagcaacag cagcagcaac aaatcagcag ccgcagcaga agacgccgca ctgatgatgc 3781 atcacagtaa caacagatac taatacaact acaacaacaa caagaacaac aacaacaaca 3841 gcaaccacag cagcagccac agcgacaaca acaaaaacaa caacactgac aacgacagga 3901 aacggaaatg aaaacggata cggaaacgta accacagacc tgaactaacc aatttgaccg 3961 cagacagaac aaatttatta cgacgcagcc gcagcagcca acttaatgta gcaaattgtc 4021 caaagcaatt tttttttgga tgcactcatt gatgtacgat tagtagttta ggtgaacgta 4081 catccaccag ctagacggtg acggaaatga gcgaacatca gagcaaagca tttggcatta 4141 ggcatatggc atatggcata tgagatgaga tatgggtgtt caaacggtag cggacaaagg 4201 tgtatagttt ttagttagaa caaagttgga tataaacaaa agaagcgaaa tataatataa 4261 aatatgtata tatatatata tcaatatata tatatatata tagatatata cacccactta 4321 tataggttaa gatccgatta taaaaacata gagaagagcg aaaatgaggg ctttctggag 4381 ttcgttaagc gctagagtgt tgtttgttta tgttgatgtt tatatacgag agccaagagt 4441 tatagcgagt tagttatgtt gacgataatg tgtttttttg atatatattg acctatatga 4501 atatgtaaac atgcagacgc aggcacaggc accccaccca tgcacaccga tgttttgccg 4561 gtgatagtga tgttgaggca caagtgcatt gcattgcatg gtggttaact ataagtacga 4621 caatgtttag tagctgacta cgaataatga cgacgatgac gggacgcaga tgcagatgca 4681 gatgcagatg cggatgtgaa tgcgattgcg aacggttgcg gatctagcgg aaagtcagac 4741 aatgacgata acgatttacg attacgatct aatgataatg ataaatatat attgatgaat 4801 attgacgcta ataacgatgg agatgatgaa aaacgttggt gcatttgttg ttagatgtat 4861 gtaatttttc ccactcgcct ttgcctaaaa gcaacacaaa attaaaacaa acaagaacga 4921 tatataaaac gtataaacac tagtaactag cggaaaagtt gcatatagaa ccacggaaat 4981 tcattcacac aaccacttac tatactatat ctgtaccatt tagcccatag tccgcagaag 5041 atcgtcgaaa caaagtcatt ttactatata aacaaaacat ccgcataata atgtaaacta 5101 cgacagaaat tgattggaaa aaaggagaaa ttgaatttgt tgtcgcgttg atttaaacct 5161 atataatgag taaaatattg tatatttaac aatctataaa acaaatatag tatgtagata 5221 atacacacaa acacacgaac ccataaataa cacacacaca cacacacaca caaatggact 5281 accgttgcgg tctaatttta tacacaccag acaaatcgaa ttgcaaataa ataaataatt 5341 aagaaagtga caatggagaa gcagagctgg agatgagatc aactcaaact agataactat 5401 acatatattt gctgattaat ttatgtaaac caatatacga tttatagcca acgcacagaa 5461 aatgaaaaac aaaaaaaagc aatacatacg aaatttgttc gaaaaaattt agctaaattc 5521 aagttgagtg ttaacattat aattcatgcg aatatgcata tattcaattt ttttttttaa 5581 ctctccatct ctcctgctcg ccattatacg aactacttaa aacatttttt tttaattaaa 5641 ttttttgtat attgcaaaaa cgtcgacgac gccacagcag cagcagctat ggatattatt 5701 tcaaaaatat atacatataa ctattatacg aataaagaga aaacaaattc attataattt 5761 tcacaatgta tgcgccgaga gcattgttat atttaataaa caacctaaaa caaaaaggac 5821 aaacaatgga aaacaaaata aaaactatgc gaataatttc cactctaaac aaaatgcaaa 5881 acaaagcaaa acaaaaaaaa aaaaaaacga agaagctgag gaactctaag tgtaataaac 5941 taattaaaaa tcgaacttct taatcaattt gatacatcca actagcatac ggaaagcatt 6001 gcattaacta acattaaacg atgtgcagag gagttaacta tagataaccg cttaaacagg 6061 gtgactattc gtagcaagtg attttttttc gctcaaacaa aaatacttaa atcactggtt 6121 aaggccctat tttccatgcg gttcttccga aagcgaggca gccagtgaac gaaaaaacct 6181 ataccaaatt caaatcactt ttccaactag ccttagattt tactaacaaa catgaaaccc 6241 tcgagaacta actatcaagc aattatcaac tagataaaga aaatatatat ttaaattaga 6301 ggccccagga gcggctgaga agggcgactt tcttttctca aaaaaacata aaaaaaaaaa 6361 acgcaaaaat aagtatgata caaaatgtat aaccctttcg tcccagatga tatatatata 6421 tatatatata tatatatgta tgtatatcct atccactaca cacacgcgcg cgcatacaaa 6481 gcatgggaaa gcgtttcatc aaaattgtgc cttttctttt tgttgttgtt gttgtcgaat 6541 cgaatcgaat cgaatttcga tgaaaatata cacacacata gacacatgta cgggcagctt 6601 tcgtatggtt tccgctcaca cttatgtaca tcccgtttac atcacattta catcctgacc 6661 cactgccacc acccccatgg aaacaaaaaa caaggaaatg gttttttgct agtcatacat 6721 acacccacga gaaactagga aaaagaaaaa gaagaagaag aaggaatctt tagccttagc 6781 gatcagtaaa gaaagtaaat caaattcaat ttcgttgaag ttcgcgatca gatcggcagt 6841 agagctatat atgctataca tatatacata tacgatagtg ctaaaaccaa aacggaaatc 6901 gatggatagt aatgagttta agaattgggt tgatataaat gaatatatgg gcaaaaaaaa 6961 aaaacacaca agtacaccca acatatgtac aatactctca tgttcatgtg cgagatacaa 7021 attggagacc ccattcggcc tcaaaatgcg ttttcattat gtattatgtc aaatgtaatt 7081 tgttcatcag cggatgaaac actcgcccac actcaaaaaa aaaaaaaaaa cacactcgaa 7141 ataaaccgta ataaaaatac gtaatcatat gcctggcatt ttcattattt agttatcatg 7201 tacttaattt tttagatttt agccgattga cgagaagtgt attcacttt //