Dbfetch
LOCUS NM_001042816 6849 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster paralytic (para), transcript variant C, mRNA. ACCESSION NM_001042816 VERSION NM_001042816.2 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 6849) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 6849) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 6849) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 6849) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 6849) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 6849) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 6849) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 6849) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 6849) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 6849) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 6849) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 6849) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 6849) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 6849) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 6849) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 6849) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 6849) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 6849) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 6849) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 6849) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 21 (bases 1 to 6849) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 22 (bases 1 to 6849) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 23 (bases 1 to 6849) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jan 31, 2011 this sequence version replaced NM_001042816.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..6849 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="X" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..6849 /gene="para" /locus_tag="Dmel_CG9907" /gene_synonym="bas; bss; CG9907; Dmel\CG9907; DmNav; DmNav1; DmNa[[v]]; DmNa[[V]]; DmNa[[v]]1; l(1)14Da; l(1)ESHS48; lincRNA.S9469; Nav1; Ocd; olfD; par; Para; para13-5; sbl; sbl-1; Scn1alpha; Shu; Shudderer; VSSC" /note="paralytic" /map="14C8-14E1" /db_xref="FLYBASE:FBgn0285944" /db_xref="GeneID:32619" CDS 269..6664 /gene="para" /locus_tag="Dmel_CG9907" /gene_synonym="bas; bss; CG9907; Dmel\CG9907; DmNav; DmNav1; DmNa[[v]]; DmNa[[V]]; DmNa[[v]]1; l(1)14Da; l(1)ESHS48; lincRNA.S9469; Nav1; Ocd; olfD; par; Para; para13-5; sbl; sbl-1; Scn1alpha; Shu; Shudderer; VSSC" /note="CG9907 gene product from transcript CG9907-RC; CG9907-PC; para-PC; bang sensitive; voltage-sensitive sodium channel; shudderer; bang senseless; bangsenseless; voltage gated sodium ion channel; paralyzed; Out-cold; Out cold; smell-blind; smellblind; paralytic; bang-senseless" /codon_start=1 /product="paralytic, isoform C" /protein_id="NP_001036281.1" /db_xref="FLYBASE:FBpp0110322" /db_xref="GeneID:32619" /db_xref="FLYBASE:FBgn0285944" /translation="MTEDSDSISEEERSLFRPFTRESLVQIEQRIAAEHEKQKELERK RAEGEVPQYGRKKKQKEIRYDDEDEDEGPQPDPTLEQGVPIPVRLQGSFPPELASTPL EDIDPYYSNVLTFVVVSKGKDIFRFSASKAMWMLDPFNPIRRVAIYILVHPLFSLFII TTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMARGFILCPFTYLRDAWNWLD FVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVII LTMFSLSVFALMGLQIYMGVLTQKCIKKFPLDGSWGNLTDENWDYHNRNSSNWYSEDE GISFPLCGNISGAGQCDDDYVCLQGFGPNPNYGYTSFDSFGWAFLSAFRLMTQDFWED LYQLVLRAAGPWHMLFFIVIIFLGSFYLVNLILAIVAMSYDELQKKAEEEEAAEEEAI REAEEAAAAKAAKLEERANAQAQAAADAAAAEEAALHPEMAKSPTYSCISYELFVGGE KGNDDNNKEKMSIRSVEVESESVSVIQRQPAPTTAHQATKVRKVSTTSLSLPGSPFNI RRGSRSSHKYTIRNGRGRFGIPGSDRKPLVLSTYQDAQQHLPYADDSNAVTPMSEENG AIIVPVYYGNLGSRHSSYTSHQSRISYTSHGDLLGGMAVMGVSTMTKESKLRNRNTRN QSVGATNGGTTCLDTNHKLDHRDYEIGLECTDEAGKIKHHDNPFIEPVQTQTVVDMKD VMVLNDIIEQAAGRHSRASDRGVSVYYFPTEDDDEDGPTFKDKALEVILKGIDVFCVW DCCWVWLKFQEWVSLIVFDPFVELFITLCIVVNTMFMAMDHHDMNKEMERVLKSGNYF FTATFAIEATMKLMAMSPKYYFQEGWNIFDFIIVALSLLELGLEGVQGLSVLRSFRLL RVFKLAKSWPTLNLLISIMGRTVGALGNLTFVLCIIIFIFAVMGMQLFGKNYTDHKDR FPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMYVGDVSCIPFFLATVVIGNLV VLNLFLALLLSNFGSSSLSAPTADNDTNKIAEAFNRIGRFKSWVKRNIADCFKLIRNK LTNQISDQPSGERTNQISWIWSEGKGVCRCISAEHGDNELELGHDEILADGLIKKGIK EQTQLEVAIGDGMEFTIHGDMKNNKPKKSKYLNNATDDDTASINSYGSHKNRPFKDES HKGSAETMEGEEKRDASKEDLGLDEELDEEGECEEGPLDGDIIIHAHDEDILDEYPAD CCPDSYYKKFPILAGDDDSPFWQGWGNLRLKTFQLIENKYFETAVITMILMSSLALAL EDVHLPQRPILQDILYYMDRIFTVIFFLEMLIKWLALGFKVYFTNAWCWLDFVIVMVS LINFVASLVGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLV CLIFWLIFAIMGVQLFAGKYFKCEDMNGTKLSHEIIPNRNACESENYTWVNSAMNFDH VGNAYLCLFQVATFKGWIQIMNDAIDSREVDKQPIRETNIYMYLYFVFFIIFGSFFTL NLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQA IVFEIVTDKKFDIIIMLFIGLNMFTMTLDRYDASDTYNAVLDYLNAIFVVIFSSECLL KIFALRYHYFIEPWNLFDVVVVILSILGLVLSDIIEKYFVSPTLLRVVRVAKVGRVLR LVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKEKSGINDVYN FKTFGQSMILLFQMSTSAGWDGVLDAIINEEACDPPDNDKGYPGNCGSATVGITFLLS YLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQQFDPEGTQYIRYD QLSEFLDVLEPPLQIHKPNKYKIISMDIPICRGDLMYCVDILDALTKDFFARKGNPIE ETGEIGEIAARPDTEGYEPVSSTLWRQREEYCARLIQHAWRKHKARGEGGGSFEPDTD HGDGGDPDAGDPAPDEATDGDAPAGGDGSVNGTAEGAADADESNVNSPGEDAAAAAAA AAAAAAAGTTTAGSPGAGSAGRQTAVLVESDGFVTKNGHKVVIHSRSPSITSRTADV" ORIGIN 1 caacaacaac aatacaagca agcacgctca caacaaaagc agcaacagca acaacaacca 61 caatagcaac tacagcaaca acaacatcag cggatagagc gagcagccag gcacaacatc 121 gatagacatc gattaacgca tcgtgctaag cggcgggcgc taatcgaaca tggcgcctcg 181 gatatagttg tagctttaat gtagcaggcg acatccatgt gcctcatgcc ttggaaatct 241 aaggctctca tcgttggccg catagacaat gacagaagat tccgactcga tatctgagga 301 agaacgcagt ttgttccgtc cctttacccg cgaatcattg gtgcaaatcg aacaacgcat 361 tgccgctgaa catgaaaagc agaaggagct ggaaagaaag agagccgagg gagaggtgcc 421 gcaatatggt cgcaagaaaa aacaaaaaga aatccgatat gatgacgagg acgaggatga 481 aggtccacaa ccggatccta cacttgaaca gggtgtgcca atacctgttc gattgcaggg 541 cagcttcccg ccggaattgg cctccactcc tctcgaggat atcgatccct actacagcaa 601 tgtactgaca ttcgtagttg taagcaaagg aaaagatatt tttcgctttt ctgcatcaaa 661 agcaatgtgg atgctcgatc cattcaatcc gatacgtcgt gtggccattt acattctagt 721 gcatccatta ttttccctat tcatcatcac cacaattctc gtcaactgca tcctgatgat 781 aatgccgaca acgcccacgg ttgagtccac tgaggtgata ttcaccggaa tctacacatt 841 tgaatcagct gttaaagtga tggcacgagg tttcatttta tgcccgttta cgtatcttag 901 agatgcatgg aattggctgg acttcgtagt aatagcttta gcttatgtga ccatgggtat 961 agatttaggt aatctagcag ccctgcgaac gtttagggtg ctgcgagcgc ttaaaaccgt 1021 agccattgtg ccaggcttga agaccatcgt cggcgccgtc atcgaatcgg tgaagaatct 1081 gcgcgatgtg attatcctga ccatgttctc cctgtcggtg ttcgcgttga tgggcctaca 1141 gatctatatg ggcgtgctca cgcagaagtg catcaagaag ttcccgctgg acggttcctg 1201 gggcaatctg accgacgaga actgggacta tcacaatcgc aatagctcca attggtattc 1261 cgaggacgag ggcatctcat ttccgttatg cggcaatata tccggtgcgg ggcaatgcga 1321 cgacgattac gtgtgcctgc aggggtttgg tccgaatccg aattatggct acaccagctt 1381 cgattcgttc ggatgggctt tcctgtccgc cttccggctg atgacacagg acttctggga 1441 ggatctgtac cagctggtgt tgcgcgccgc cggaccatgg cacatgctgt tctttatagt 1501 catcatcttc ctaggttcat tctatcttgt gaatttgatt ttggccattg ttgccatgtc 1561 gtatgacgaa ttgcaaaaga aggccgaaga agaagaggct gccgaagagg aggcgatacg 1621 tgaagcggaa gaagctgccg ccgccaaagc ggccaagctg gaggagcggg ccaatgcgca 1681 ggctcaggca gcagcggatg cggctgccgc cgaagaggct gcactgcatc cggaaatggc 1741 caagagtccg acgtattctt gcatcagcta tgagctattt gttggcggcg agaagggcaa 1801 cgatgacaac aacaaagaga agatgtccat tcggagcgtc gaggtggagt cggagtcggt 1861 gagcgttata caaagacaac cagcacctac cacagcacac caagctacca aagttcgtaa 1921 agtgagcacg acatccttat ccttacctgg ttcaccgttt aacatacgca ggggatcacg 1981 tagttctcac aagtacacga tacggaacgg acgtggccgc tttggtatac ccggtagcga 2041 tcgtaagcca ttggtattgt caacatatca ggatgcccag cagcacttgc cctatgccga 2101 cgactcgaat gccgtcaccc cgatgtccga agagaatggg gccatcatag tgcccgtgta 2161 ctatggcaat ctaggctccc gacactcatc gtatacctcg catcagtccc gaatatcgta 2221 tacctcacat ggcgatctac tcggcggcat ggccgtcatg ggcgtcagca caatgaccaa 2281 ggagagcaaa ttgcgcaacc ggaacacacg caatcaatca gtgggcgcca ccaatggcgg 2341 caccacctgt ctggacacca atcacaagct cgatcatcgc gactacgaaa ttggcctgga 2401 gtgcacggac gaagctggca agattaaaca tcatgacaat ccttttatcg agcccgtcca 2461 gacacaaacg gtggttgata tgaaagatgt gatggtcctg aatgacatca tcgaacaggc 2521 cgctggtcgg cacagtcggg caagcgatcg cggtgtctcc gtttactatt tcccaacaga 2581 ggacgatgac gaggatgggc cgacgttcaa agacaaggca ctcgaagtga tcctcaaagg 2641 catcgatgtg ttttgtgtgt gggactgttg ctgggtttgg ttgaaatttc aggagtgggt 2701 atcgctcatc gtcttcgatc ccttcgtcga gctcttcatc acgctgtgca ttgtggtcaa 2761 cacgatgttc atggcaatgg atcaccacga tatgaacaag gagatggaac gcgtgctcaa 2821 gagtggcaac tatttcttca ccgccacctt tgccatcgag gccaccatga agctaatggc 2881 catgagcccc aagtactatt tccaggaggg ctggaacatc ttcgacttca ttatcgtggc 2941 cctatcgcta ttggaactgg gactcgaggg tgtccagggt ctgtccgtat tgcgttcctt 3001 tcgattgctg cgtgttttca agctggccaa atcgtggccg acgctgaatt tgctcatatc 3061 gattatgggc cgcactgtcg gcgccctcgg caatctgacc ttcgtcctgt gcattattat 3121 cttcatattc gcggtcatgg gcatgcagct gtttggcaag aactacacag atcacaagga 3181 ccgctttccg gatggcgacc tgccgcgctg gaacttcacc gactttatgc acagcttcat 3241 gatcgtgttc cgggtgctct gcggagaatg gatcgagtcc atgtgggact gcatgtacgt 3301 gggcgatgtc tcgtgcattc ccttcttctt ggccaccgtt gtcatcggca atcttgtggt 3361 acttaacctt ttcttagcct tgcttttgtc caattttggc tcatctagct tatcagcgcc 3421 gactgccgat aacgatacga ataaaatagc cgaggccttc aatcgaattg gccgatttaa 3481 aagttgggtt aagcgtaata ttgctgattg tttcaagtta atacgtaaca aattgacaaa 3541 tcaaataagt gatcaaccat caggtgagag gaccaaccag atcagttgga tttggagcga 3601 aggcaaaggc gtttgtcgtt gtatatctgc agagcatggt gacaacgaac tggagctggg 3661 ccacgacgag atcctcgccg acggcctcat caagaagggg atcaaggagc agacgcaact 3721 ggaggtggcc atcggggatg gcatggaatt cacgatacac ggcgacatga agaacaacaa 3781 gccgaagaaa tccaaatatc taaataacgc aacggacgac gacactgcca gcattaactc 3841 atatggtagc cataagaatc gaccattcaa ggacgagagc cacaagggca gcgccgagac 3901 gatggagggc gaggagaagc gcgacgccag caaggaggat ttaggtctcg acgaggaact 3961 ggacgaggag ggcgaatgcg aggagggccc gctcgacggt gatatcatta ttcatgcaca 4021 cgacgaggat atactcgatg aatatccagc tgattgctgc cccgattcgt actataagaa 4081 atttccgatc ttagccggtg acgatgactc gccgttctgg caaggatggg gcaatttacg 4141 actgaaaact tttcaattaa ttgaaaataa atattttgaa acagctgtta tcactatgat 4201 tttaatgagt agcttagctt tggcattaga agatgtacat ctgccacaaa gacccatact 4261 gcaggatatt ttatactata tggacagaat atttacggtt atattcttct tggaaatgtt 4321 aatcaagtgg ttggcgctcg gcttcaaagt gtacttcacc aacgcgtggt gttggctcga 4381 tttcgtgatt gtcatggtat cgcttatcaa cttcgttgct tcacttgttg gagctggtgg 4441 tattcaagcc ttcaagacta tgcgaacgtt aagagcactg agaccactac gtgccatgtc 4501 ccgtatgcag ggcatgaggg tcgtcgttaa tgcgctggta caagctatac cgtccatctt 4561 caatgtgcta ttggtgtgtc taatattttg gctaattttt gccataatgg gtgtacagct 4621 ttttgctgga aaatatttta agtgcgagga catgaatggc acgaagctca gccacgagat 4681 cataccaaat cgcaatgcct gcgagagcga gaactacacg tgggtgaatt cagcaatgaa 4741 tttcgatcat gtaggtaacg cgtatctgtg ccttttccaa gtggccacct tcaaaggctg 4801 gatacaaatc atgaacgatg ctatcgattc acgagaggtg gacaagcaac caattcgtga 4861 aacgaacatc tacatgtatt tatatttcgt attcttcatc atatttggat catttttcac 4921 actcaatctg ttcattggtg ttatcattga taattttaat gagcaaaaga aaaaagcagg 4981 tggatcatta gaaatgttca tgacagaaga tcagaaaaag tactataatg ctatgaaaaa 5041 gatgggctct aaaaaaccat taaaagccat tccaagacca aggtggcgac cacaagcaat 5101 agtctttgaa atagtaaccg ataagaaatt cgatataatc attatgttat tcattggtct 5161 gaacatgttc accatgaccc tcgatcgtta cgatgcgtcg gacacgtata acgcggtcct 5221 agactatctc aatgcgatat tcgtagttat tttcagttcc gaatgtctat taaaaatatt 5281 cgctttacga tatcactatt ttattgagcc atggaattta tttgatgtag tagttgtcat 5341 tttatccatc ttaggtcttg tacttagcga tattatcgag aagtacttcg tgtcgccgac 5401 cctgctccga gtggtgcgtg tggcgaaagt gggccgtgtc cttcgactgg tgaagggagc 5461 caagggcatt cggacactgc tcttcgcgtt ggccatgtcg ctgccggccc tgttcaacat 5521 ctgcctgctg ctgttcctgg tcatgttcat ctttgccatt ttcggcatgt cgttcttcat 5581 gcacgtgaag gagaagagcg gcatcaacga cgtctacaac ttcaagacct ttggccagag 5641 catgatcctg ctctttcaga tgtcgacgtc agccggttgg gatggtgtac tggacgccat 5701 tatcaatgag gaagcatgcg atccacccga caacgacaaa ggctatccgg gcaattgtgg 5761 ttcagcgacc gttggaataa cgtttctcct ctcataccta gttataagct ttttgatagt 5821 tattaatatg tacattgctg tcattctcga gaactatagt caggccaccg aggacgtgca 5881 agagggtcta accgacgacg actacgacat gtactatgag atctggcagc aattcgatcc 5941 ggagggcacc cagtacatac gctatgatca gctgtccgaa ttcctggacg tactggagcc 6001 cccgctgcag atccacaaac cgaacaagta caagatcata tcgatggaca tacccatctg 6061 tcgcggtgac ctcatgtact gcgtcgacat cctcgacgcc cttacgaaag acttctttgc 6121 gcggaagggc aatccgatag aggagacggg tgagattggt gagatagcgg cccgcccgga 6181 tacggagggc tacgagcccg tctcatcaac gctgtggcgt cagcgtgagg agtactgcgc 6241 ccggctaatc cagcacgcct ggcgaaagca caaggcgcgc ggcgagggag gtgggtcctt 6301 tgagccggat acggatcatg gcgatggcgg tgatccggat gccggggacc cggcgcccga 6361 tgaagcaacg gacggcgatg cgcccgctgg tggagatggt agtgttaacg gtactgcaga 6421 aggagctgcc gatgccgatg agagtaatgt aaatagtccg ggtgaggatg cagcggcggc 6481 ggcagcagca gcagcagcag cggcggcggc gggcacgacg acggcgggaa gtcccggagc 6541 gggtagcgcc gggcgacaga ccgccgttct cgtggagagc gacgggttcg tgacgaagaa 6601 cggccacaag gtggtcatcc actcgcgatc gccgagcatc acgtcgcgca cggcggatgt 6661 ctgagccagg cctcgccccc ccctccaaga tgcacgcgag tattagcatg agtacgtgtt 6721 ggatgttgca tgttgcatca gcgatgcagc agcgacagtg agctaacaac aacagcaaca 6781 aggcgaacaa caagcataat tttctgctat ataatgaaag aacaccatac aaacaaatac 6841 aacaacaat //