Dbfetch
LOCUS NM_001015222 5486 bp mRNA linear INV 26-DEC-2023 DEFINITION Drosophila melanogaster SET domain containing 1 (Set1), transcript variant B, mRNA. ACCESSION NM_001015222 VERSION NM_001015222.3 DBLINK BioProject: PRJNA164 BioSample: SAMN02803731 KEYWORDS RefSeq. SOURCE Drosophila melanogaster (fruit fly) ORGANISM Drosophila melanogaster Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. REFERENCE 1 (bases 1 to 5486) AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K., Strelets,V., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015) PUBMED 26109357 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 5486) AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B., Russo,S.M. and Gelbart,W.M. CONSRTM FlyBase Consortium TITLE Gene Model Annotations for Drosophila melanogaster: The Rule-Benders JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015) PUBMED 26109356 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 5486) AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I., Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R., Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G., Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N., Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A., Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E. TITLE The Release 6 reference sequence of the Drosophila melanogaster genome JOURNAL Genome Res 25 (3), 445-458 (2015) PUBMED 25589440 REFERENCE 4 (bases 1 to 5486) AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M., Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F., Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E. TITLE Sequence finishing and mapping of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1625-1628 (2007) PUBMED 17569867 REFERENCE 5 (bases 1 to 5486) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. TITLE The Release 5.1 annotation of Drosophila melanogaster heterochromatin JOURNAL Science 316 (5831), 1586-1591 (2007) PUBMED 17569856 REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325] REFERENCE 6 (bases 1 to 5486) AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D., Ashburner,M. and Anxolabehere,D. TITLE Combined evidence annotation of transposable elements in genome sequences JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005) PUBMED 16110336 REFERENCE 7 (bases 1 to 5486) AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A., Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A., Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W., Celniker,S.E., Rubin,G.M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002) PUBMED 12537574 REFERENCE 8 (bases 1 to 5486) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002) PUBMED 12537573 REFERENCE 9 (bases 1 to 5486) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J., Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M., Rubin,G.M. and Lewis,S.E. TITLE Annotation of the Drosophila melanogaster euchromatic genome: a systematic review JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002) PUBMED 12537572 REFERENCE 10 (bases 1 to 5486) AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W., Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E., Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M., Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S., Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M., Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W., Gibbs,R.A. and Rubin,G.M. TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002) PUBMED 12537568 REFERENCE 11 (bases 1 to 5486) AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D., Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F., George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N., Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X., Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D., Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L., Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S., Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z., Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J., Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J., Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z., Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C., Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A., Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C., McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C., Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L., Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K., Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S., Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K., Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I., Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C., Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R., Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A., Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT, Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F., Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H., Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O., Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C. TITLE The genome sequence of Drosophila melanogaster JOURNAL Science 287 (5461), 2185-2195 (2000) PUBMED 10731132 REFERENCE 12 (bases 1 to 5486) AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R., Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R., Smith,E., Yu,C. and Rubin,G. CONSRTM Berkeley Drosophila Genome Project TITLE Drosophila melanogaster release 4 sequence JOURNAL Unpublished REFERENCE 13 (bases 1 to 5486) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 14 (bases 1 to 5486) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 15 (bases 1 to 5486) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (10-NOV-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 16 (bases 1 to 5486) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 17 (bases 1 to 5486) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 18 (bases 1 to 5486) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 19 (bases 1 to 5486) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 20 (bases 1 to 5486) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 21 (bases 1 to 5486) CONSRTM FlyBase TITLE Direct Submission JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA REFERENCE 22 (bases 1 to 5486) AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Karpen,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 23 (bases 1 to 5486) AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S., Svirskas,R. and Rubin,G. TITLE Direct Submission JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA REMARK Direct Submission REFERENCE 24 (bases 1 to 5486) AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H. CONSRTM Drosophila Heterochromatin Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project, Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 64-121, Berkeley, CA 94720, USA REFERENCE 25 (bases 1 to 5486) AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J. TITLE Direct Submission JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jan 16, 2013 this sequence version replaced NM_001015222.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.54 URL :: http://flybase.org ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..5486 /organism="Drosophila melanogaster" /mol_type="mRNA" /db_xref="taxon:7227" /chromosome="3L" /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]" gene 1..5486 /gene="Set1" /locus_tag="Dmel_CG40351" /gene_synonym="aaf45425 Dm; CG17395; CG17396; CG40351; Dmel\CG40351; dSet-1; dset1; dSet1; dSET1; l(3)h5; l5; set1; SET1; SetD1; SETD1" /note="SET domain containing 1; Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org" /map="80F9-80F9" /db_xref="FLYBASE:FBgn0040022" /db_xref="GeneID:3354971" CDS 278..5203 /gene="Set1" /locus_tag="Dmel_CG40351" /gene_synonym="aaf45425 Dm; CG17395; CG17396; CG40351; Dmel\CG40351; dSet-1; dset1; dSet1; dSET1; l(3)h5; l5; set1; SET1; SetD1; SETD1" /note="CG40351 gene product from transcript CG40351-RB; CG40351-PB; Set1-PB; SET domain-containing 1; lethal5; lethal 5" /codon_start=1 /product="SET domain containing 1, isoform B" /protein_id="NP_001015222.1" /db_xref="FLYBASE:FBpp0112594" /db_xref="GeneID:3354971" /db_xref="FLYBASE:FBgn0040022" /translation="MQDVRNINLVNNSSNSHDSSLANSKMPRNFKLLSDPQLVKCGTR LYRYDGLMPGDPSYPTITPRDPRNPLIRIRARAVEPLMLLIPRFVIDSDYVGQPPAVE VTIVNLNDNIDKQFLASMLDKCGTSDEINIYHHPITNKHLGIARIVFDSTKGARQFVE KYNQKSVMGKILDVFCDPFGATLKKSLESLTNSVAGKQLIGPKVTPQWTFQQAALEDT EFIHGYPEKNGEHIKDIYTTQTNHEIPNRSRDRNWNRDKERERDRHFKERSRHSSERS YDRDRGMRENVGTSIRRRRTFYRRRSSDISPEDSRDILIMTRERSRDSDSRPRDYCRS RERESFRDRKRSHEKGRDQPREKREHYYNSSKDREYRGRDRDRSAEIDQRDRGSLKYC SRYSLHEYIETDVRRSSNTISSYYSASSLPIASHGFNSCSFPSIENIKTWSDRRAWTA FQPDFHPVQPPPPPPEEIDNWDEEEHDKNSIVPTHYGCMAKLQPPVPSNVNFATKLQS VTQPNSDPGTVDLDTRIALIFKGKTFGNAPPFLQMDSSDSETDQGKPEVFSDVNSDSN NSENKKRSCEKNNKVLHQPNEASDISSDEELIGKKDKSKLSLICEKEVNDDNMSLSSL SSQEDPIQTKEGAEYKSIMSSYMYSHSNQNPFYYHASGYGHYLSGIPSESASRLFSNG AYVHSEYLKAVASFNFDSFSKPYDYNKGALSDQNDGIRQKVKQVIGYIVEELKQILKR DVNKRMIEITAFKHFETWWDEHTSKARSKPLFEKADSTVNTPLNCIKDTSYNEKNPDI NLLINAHREVADFQSYSSIGLRAAMPKLPSFRRIRKHPSPIPTKRNFLERDLSDQEEM VQRSDSDKEDSNVEISDTARSKIKGPVPIQESDSKSHTSGLNSKRKGSASSFFSSSSS STSSEAEYEAIDCVEKARTSEEDSPRGYGQRNLNQRTTTIRNRNLVGTMDVINVRNLC SGSNEFKKENVTKRTKKNIYSDTDEDNDRTLFPALKEKNISTILSDLEEISKDSCIGL DENGIEPTILRKIPNTPKLNEECRRSLTPVPPPGYNEEEIKKKVDCKQKPSFEYDRIY SDSEEEKEYQERRKRNTEYMAQMEREFLEEQEKRIEKSLDKNLQSPNNIVKNNNSPRN KNDETRKTAISQTRSCFESASKVDTTLVNIISVENDINEFGPHEEGDVLTNGCNKMYT NSKGKTKRTQSPVYSEGGSSQASQASQVALEHCYSLPPHSVSLGDYPSGKVNETKNIL KREAENIAIVSQMTRTGPGRPRKDPICIQKKKRDLAPRMSNVKSKMTPNGDEWPDLAH KNVHFVPCDMYKTRDQNEEMVILYTFLTKGIDAEDINFIKMSYLDHLHKEPYAMFLNN THWVDHCTTDRAFWPPPSKKRRKDDELIRHKTGCARTEGFYKLDVREKAKHKYHYAKA NTEDSFNEDRSDEPTALTNHHHNKLISKMQGISREARSNQRRLLTAFGSMGESELLKF NQLKFRKKQLKFAKSAIHDWGLFAMEPIAADEMVIEYVGQMIRPVVADLRETKYEAIG IGSSYLFRIDMETIIDATKCGNLARFINHSCNPNCYAKVITIESEKKIVIYSKQPIGI NEEITYDYKFPLEDEKIPCLCGAQGCRGTLN" ORIGIN 1 tttgcattgt gattcaatat ttcatatatt tgagagttaa ttttatcatc caaccaatat 61 aatgattaaa aaagtaattt aattatttgt tttttaatta aaaaagcagc gtgaacgatt 121 ttaatataat tatatattat atattcgctg ttgatccctt tcaaataaaa acatcgcaga 181 aaattttttg tgatatttct aaatattttt atattctatt attttgttaa taagtaaaat 241 agttcctgag ttttaggttt gttcataatt gacacagatg caggacgttc ggaatatcaa 301 cctggtcaac aattccagca acagccatga ttcgtctctg gcaaactcca aaatgccgcg 361 caactttaaa ctgctatctg atccacagtt ggttaaatgt ggtaccagac tctatcgtta 421 cgatggttta atgccaggag acccgtccta tccaacaata acacctagag atcctcggaa 481 tccacttatt cgcatacgcg ccagggctgt tgaaccactt atgcttctta ttccgaggtt 541 tgtcatcgat agcgactacg tgggccagcc acctgcagtc gaagttacaa tagtgaacct 601 aaatgataac atcgacaagc aatttcttgc tagcatgctg gacaaatgtg gaacatctga 661 tgaaataaat atttaccatc atcccatcac aaacaaacac ttgggcattg cacgtatagt 721 gtttgatagt acaaagggag cgagacaatt cgttgaaaaa tacaatcaaa agtctgtaat 781 gggaaagatc ttagatgtgt tttgcgatcc ttttggtgcc acattaaaaa aatctcttga 841 gagccttaca aattcagtcg ctggaaaaca attaataggt ccaaaagtaa caccgcaatg 901 gacatttcag caggcggctt tggaggacac cgaattcatc cacggatatc ctgaaaagaa 961 cggcgaacac ataaaggata tctacaccac acaaaccaat catgaaattc caaaccgcag 1021 tagggatcga aactggaatc gcgacaagga aagagaaaga gatcgccatt ttaaggagcg 1081 cagtcgacac tcgtcagagc gaagttatga ccgtgatcgt ggaatgcgag aaaacgttgg 1141 aacttcaata aggcgtcgcc gtacttttta tcgacgccgt tctagtgata tatcgccgga 1201 agattctcgg gatatattga tcatgacaag agaaagatct agagattcag attcacgtcc 1261 tcgtgattat tgtcgttcta gggagcgaga gtcgtttcga gaccgtaaaa gatctcatga 1321 aaaaggccga gaccagccca gagaaaaaag agaacattat tataactcat ctaaagatcg 1381 agagtaccgc gggagagatc gcgaccgatc tgctgaaatc gatcaaaggg atcgcggaag 1441 tcttaagtat tgtagccgct attcattgca tgaatatata gaaactgatg ttagacgttc 1501 ttcgaataca ataagtagtt actattccgc ttccagtctt cctattgcaa gccatggctt 1561 caatagctgt tcttttcctt caattgaaaa tattaagaca tggtctgatc gaagagcttg 1621 gactgcgttt cagcctgact ttcatccagt acaaccaccc ccgccgccac cagaagagat 1681 tgacaactgg gatgaagagg aacacgacaa aaatagtatt gtgcctaccc attatggttg 1741 catggcaaaa cttcaaccgc cagtgccgtc aaacgtgaat ttcgcgacta aattacagtc 1801 agttacacaa ccgaattccg atccagggac cgtagattta gatactcgaa tagcattaat 1861 atttaaagga aaaacttttg gaaatgcacc gccttttctt caaatggata gcagcgattc 1921 agaaacagat caaggcaaac ctgaagtttt ttcggatgtt aattccgatt caaacaactc 1981 agagaacaaa aaaaggtcat gtgaaaaaaa taataaagtt ctccatcagc caaatgaagc 2041 aagtgatata tcaagtgatg aagaactaat aggtaaaaag gacaagtcaa aactcagttt 2101 aatttgtgaa aaggaagtaa atgatgacaa tatgtcttta tcgagcctat cttcccagga 2161 ggatcctatc cagaccaagg aaggtgcaga gtataagagt attatgtcat cttatatgta 2221 ttcccattca aatcaaaatc ctttttatta ccatgcttca ggctatgggc actatctttc 2281 cggtattccg tctgaatctg caagtcgatt attttcaaat ggcgcttacg tgcattctga 2341 atatttaaaa gctgttgcat catttaattt tgattcgttt tctaagccat acgactacaa 2401 taaaggtgct ctatcagatc agaatgatgg aatacgccaa aaagtaaaac aagtaattgg 2461 ctatattgtc gaggagctaa aacagatttt aaaaagagac gttaataagc gcatgattga 2521 gataactgca tttaaacatt ttgagacgtg gtgggacgag catacatcaa aagctcgttc 2581 aaagccacta ttcgaaaaag cagactccac tgtcaataca ccattaaatt gtattaaaga 2641 tacttcttat aacgaaaaga atcctgacat aaatcttctt atcaatgccc atagggaagt 2701 cgcagatttt caatcttact ccagtatagg cttacgggca gcaatgccca agctgccatc 2761 gtttcggcgt ataagaaaac atcctagccc tataccaacc aaaagaaatt ttttggaaag 2821 agatttaagt gaccaagagg aaatggtgca acgctccgac tctgataagg aggattctaa 2881 tgtggaaatc tccgatactg cacgttctaa aattaaaggt ccagttccaa ttcaagagtc 2941 agacagtaaa tcgcatacat ctggtcttaa ttcaaaaaga aagggaagtg cttcaagttt 3001 tttttcatct tcgtcttctt ccacttctag tgaagctgag tatgaagcca ttgattgtgt 3061 agaaaaggct aggactagtg aggaagatag tcctcgagga tatggtcaaa gaaatctgaa 3121 tcaacgaaca acaactatta gaaacagaaa tctagtgggt acaatggatg ttataaatgt 3181 gagaaattta tgttcgggct caaatgaatt caaaaaagag aacgtaacaa agcgcacaaa 3241 aaagaatatt tattccgata cagatgaaga taatgataga acgttgtttc ccgctttaaa 3301 agaaaaaaat atttcaacaa ttttatctga tctcgaagaa ataagtaaag atagttgcat 3361 tggattggat gaaaacggga ttgaacccac aatattaaga aagattccaa acacgccaaa 3421 actgaatgaa gagtgtaggc gctctcttac ccccgttcca cctccgggtt acaatgagga 3481 agaaattaaa aagaaggtgg attgtaaaca aaagccgtca tttgaatacg atagaattta 3541 cagcgactcc gaggaggaga aagaatatca ggaaagaagg aaaagaaata ctgagtacat 3601 ggctcaaatg gaacgagaat ttttagagga acaagaaaaa aggattgaaa agtcattgga 3661 taaaaaccta cagtcgccta ataacattgt aaaaaacaat aactccccaa gaaataaaaa 3721 tgacgaaact agaaaaacag ctatttccca aacaagatca tgttttgaaa gtgcaagtaa 3781 agttgacact actctagtca atataataag tgttgaaaac gatataaacg aatttggccc 3841 tcatgaagag ggggatgttc ttacaaacgg ttgtaacaaa atgtatacaa attcaaaggg 3901 taaaaccaaa agaactcaat cgccagtgta ttctgagggc ggttccagcc aagcttctca 3961 ggcgagtcag gttgcgctag agcattgtta ttcgttgccg ccacactcag tttctttggg 4021 cgattatcca tctggtaagg tgaatgaaac taaaaacatt ttaaaacgag aagcagagaa 4081 cattgcaatt gttagccaaa tgacgaggac aggtcccggc cgacctcgca aggacccaat 4141 atgtattcaa aagaaaaaga gagatttggc ccccagaatg tcaaatgtaa agtctaaaat 4201 gacaccaaac ggagatgaat ggcccgattt ggcacacaaa aatgtacatt ttgttccgtg 4261 tgatatgtat aaaactcgtg atcagaatga agaaatggtt attttgtaca cttttttaac 4321 aaaaggcatt gatgccgaag atataaactt tataaaaatg agttatttgg accatttgca 4381 taaggaaccg tacgctatgt ttttaaataa tactcactgg gtggatcact gcacaactga 4441 ccgagctttt tggccaccgc catcaaaaaa gcgaagaaaa gacgacgaac tgatccgaca 4501 taagactgga tgtgcgcgaa ctgaaggatt ttacaaatta gatgttcgag aaaaggctaa 4561 gcataagtac cattatgcta aagccaatac agaagattcc tttaatgaag atcggagcga 4621 tgaacctaca gcacttacaa atcatcatca caataaatta atttctaaaa tgcaaggaat 4681 ttcccgcgaa gctcgctcaa accagagaag acttttaaca gcctttggtt ctatgggtga 4741 gtctgagctt ttaaaattta atcagctaaa gtttcggaag aaacagctta agtttgcaaa 4801 atctgcgata catgattggg gattatttgc aatggagccc atagctgcag acgaaatggt 4861 tattgaatat gttggtcaga tgattcgacc tgtagttgct gatctaagag aaacaaagta 4921 tgaagcaatt gggattggga gttcctattt gtttcgaatt gacatggaaa ctataattga 4981 cgcaactaaa tgtggaaact tagctcggtt tataaatcac agttgcaatc cgaattgcta 5041 cgctaaggtt ataactattg aatctgaaaa gaagatagta atatattcaa agcaacccat 5101 tggtatcaac gaggaaataa cttacgacta taaatttcca ctagaagacg aaaaaatacc 5161 ttgtctatgc ggcgcccaag gatgtcgggg tacacttaac taatacttat ttacaacaat 5221 gaattaaata ttttagagca cataaattta atttgttcat aaaatccaaa gtggggtacg 5281 tgtaagtata tatagttttt tttataactt aaaactataa ttaattatta taaaaattat 5341 atcaacgagg tcagaggtgc tgttcaaaat ggtttaggtc taaattaagc taaaatactt 5401 tacttataaa aacaatatgt atatactaaa acccatttga tctgtaaaca cgaacgaaaa 5461 tgcaataaat acattatctt aaattt //