Dbfetch
ID KIR00130; SV 2; standard; DNA; HUM; 11137 BP. XX AC KIR00130; XX SV KIR00130.2 XX DT 29-APR-2005 (Rel. 1.2.0, Created, Version 1) DT 21-MAY-2010 (Rel. 2.10.0, Sequence Updated, Version 2) DT 16-DEC-2021 (Rel. 2.11.0, Current Release, Version 2) XX DE KIR2DL4*0060201, Human Killer-cell Immunoglobulin-like Receptor XX KW Human Killer-cell Immunoglobulin-like Receptor; KIR2DL4*0060201; XX OS Homo Sapiens (human) OC Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates; OC Catarrhini; Hominidae; Homo. XX CC -------------------------------------------------------------------------- CC IPD-KIR Release Version 2.11.0 CC -------------------------------------------------------------------------- CC Copyrighted by the IPD Database, Distributed under the Creative Commons CC Attribution-NoDerivs License, see; CC http://www.ebi.ac.uk/ipd/licence.html for further details. CC -------------------------------------------------------------------------- XX RN [1] RP 1-11137 RX PUBMED; 17610421. RA Shulse C, Steiner NK, Hurley CK; RT "Allelic diversity in KIR2DL4 in a bone marrow transplant population: RT Description of four novel alleles."; RL Tissue Antigens 70:157-9(2007). XX CC -------------------------------------------------------------------------- CC The sequence below is the official allele sequence as approved by the CC KIR Nomenclature Committee. CC Any cross references may differ from the sequence shown below. CC -------------------------------------------------------------------------- XX DR EMBL; AY789062; AY789062.0. DR EMBL; DQ979373; DQ979373.0. DR EMBL; GU182349; GU182349.0. DR EMBL; GU182351; GU182351.0. DR EMBL; LR593607; LR593607.0. XX FH Key Location/Qualifiers FH FT source 1..11137 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT /ethnic="Caucasoid" FT /cell_line="DKMS-LSL_ID14829466" FT /cell_line="G085" FT /cell_line="G248" FT /cell_line="J42" FT /cell_line="RDP14" FT CDS join(268..307,507..542,1409..1693,..,5449..5499,9743..9847, FT 10309..10361,10461..10730) FT /codon_start=1 FT /gene="KIR2DL4" FT /allele="KIR2DL4*0060201" FT /product="KIR2DL4 Killer-cell Immunoglobulin-like Receptor" FT /translation="MSMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGG FT HVTLRCHYRRGFNIFTLYKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHS FT PTEWSAPSNPLVIMVTGLYEKPSLTARLGPTVRAGENVTLSCSSQSSFDIYHLSREGEA FT HELRLPAVPSINGTFQADFPLGPATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTGNPS FT SSWPSPTEPSFKTGIARHLHAVIRYSVAIILFTILPFFLLHRWCSKKKNAAVMNQEPAG FT HRTVNREDSDEQDPQEVTYAQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPNAEPRA FT LSPAHEHHSQALMGSSRETTALSQTQLASSNVPAAGI" FT UTR 1..267 FT exon 268..307 FT /number="1" FT intron 308..506 FT /number="1" FT exon 507..542 FT /number="2" FT intron 543..1408 FT /number="2" FT exon 1409..1693 FT /number="3" FT intron 1694..2860 FT /number="3/4" FT intron 2861..5448 FT /number="4" FT exon 5449..5499 FT /number="5" FT intron 5500..9742 FT /number="5" FT exon 9743..9847 FT /number="6" FT intron 9848..10308 FT /number="6" FT exon 10309..10361 FT /number="7" FT intron 10362..10460 FT /number="7" FT exon 10461..10730 FT /number="8" FT UTR 10731..11137 SQ Sequence 11137 BP; 2832 A; 2670 C; 2675 G; 2960 T; 0 other; gcaggggtaa gtgagtctga gatgtgtttt gagcctggcc gttgcgcatg atgtgaagtg 60 acaagtctag tctgcagttt tcagaaaccc tcattcctcc cttgactgat tcaccacttg 120 aacctcatat gacgtagaag aagcctacct atgtcccctt cacatgttgt ggtcaatgtg 180 tcaactgcac gatccgggcc cctcaccaca tcctctgcac cggtcagtcg agccgagtca 240 ctgcgtcctg gcagcagaag ctgcaccatg tccatgtcac ccacggtcat catcctggca 300 tgtcttggtg agtcctggaa gggaaggagc accagggtta cactatgggc ctgcagattg 360 ggtgtctccc cagcagagag ccatgttctg aagcaagtga gtggtgagga tgagttaatt 420 ttcagtccag cgtggcgccc agtggctcag gaggaaaggg taggttgctg ccgagatgaa 480 tagttcatca tgatctttct ttgcagggtt cttcttggac cagagtgtgt gggcacacgt 540 gggtgagtcc ttccccaaat gatgggttgc catcttcacc ccaatacaag tgaattttcc 600 ggaaatggga gggaggcagc acagagggtg ggctgatggg ctgaccatgg gaaggcctgg 660 ggggagtctc tcatgaacta gtaagaggag atcctgggag tctctcatga actagtaaga 720 ggagatcttg ggagtctctc atgaactagt aagaggagat cctggtatgc tcagccttct 780 gttttgtctt agccctcccc agcctttctt ccccatggct gagttgagct ctgtgtggcc 840 caggcgggat actgaggtgc tcaaagctgg ggtgtgtggg gggatgtggt gtcaccgaca 900 gaggagggaa gggtagcagt gttaggaaca gcaggtcctc tgaggacaag agggtaactc 960 acaccctcca gcgtttccat gacggtaggg gctgcagtgt ggctgctgtc attctgccag 1020 aagaggtggg ggaaccacag ccacgaccct gccattccaa atcctctgat ggagctcagt 1080 tgtttattgt ggttcaggca ttagctaata ttccattcac aaaggtcata ccctccaccc 1140 catgtctact ttgtgttgtt tggtgtaact aatcttgcag tattaaaatc tagtaagagt 1200 cccttactca gcacctgctc agttctcaac tgacactttt gttgtaggga gacgccacgt 1260 ctatgcggga tgggtccttc ctgtagcccc aggcacccag gtgtggtagg agccttagaa 1320 agaagaaatg gggagaatct tctgagcaca gggagggagg ggcagctcaa catactcctc 1380 tctgaggcgg catctccttc tccccaaggt ggtcaggaca agcccttctg ctctgcctgg 1440 cccagcgctg tggtgcctca aggaggacac gtgactcttc ggtgtcacta tcgtcgtggg 1500 tttaacatct tcacgctgta caagaaagat ggggtccctg tccctgagct ctacaacaga 1560 atattctgga acagtttcct cattagccct gtgaccccag cacacgcagg gacctacaga 1620 tgtcgaggtt ttcacccgca ctcccccact gagtggtcgg cacccagcaa ccccctggtg 1680 atcatggtca caggtcagag ggctcctgtc tgggcttctc cttgtcccac ctcctgagtc 1740 ccagagcttc tggtgggggt gtccaccaga gtccgatcat ccaggcccca actatatttg 1800 gggtaaaggg ggattgaata caggggaatg ggtgctgtgt tggaaagaat aactgtcccc 1860 atcgatggcc acattgtaat ccttggagcc tgtgactatg ttatagggca ggggactgaa 1920 ggggaagatg gagctcaggt tgttgatgag ttgaccttga gatggggaga tggcctggac 1980 tctcccactg ggctcagtgt aatcacaagg gtccatatga gtggagaagg aagaggagaa 2040 tggggattag agcagcatcg tgggatactc caccagccac tgtgggcttt gaaggtggag 2100 gaagaccacg agccacgaag gggctggaga aatcaatgga actgattctc ccgagtctcc 2160 agagggaatg cagccctgca gatgccttga ttgtagccca ggaagaacag ggtctgattt 2220 ctgtctccag aagtggaagg ggtcagtgtg ttctctcctg ccgccatgtt tgtgataatt 2280 ttctccagca acaacaggaa accaacacag gaacccaggt gaaggacaag ttaaaaaacc 2340 aaacaagaag gttggctacc ctgagatcag caagggtgca ctgctgatgc caccaccagg 2400 ctggaaccac atagggaggg atcgacagga agagttgggg gtggagggtg agagagagag 2460 agagagcact aggccataga gcagggcagt gagttctcag ctcaggtggg aggggagctg 2520 tgacaaggaa gaacctccct gaggaaactg cctcttctcc ttccaggtct atatgagaaa 2580 ccttcgctta cagcccggct gggccccacg gttcgcgcag gagagaacgt gaccttgtcc 2640 tgcagctccc agagctcctt tgacatctac catctatcca gggaggggga agcccatgaa 2700 cttaggctcc ctgcagtgcc cagcatcaat ggaacattcc aggccgactt ccctctgggt 2760 cctgccaccc acggagagac ctacagatgc ttcggctctt tccatggatc tccctacgag 2820 tggtcagacc cgagtgaccc actgcctgtt tctgtcacag gtgaggaaag ccaatgtctg 2880 tcccatgtcc tatggtccta gagccttagc tgaggagctt cctgctgatg atggagagaa 2940 gcatggacag atgtggagag aagatgcagc atggtgtgag ggtgggatca gggcacagga 3000 tggcagacag ggcacctcca aaccctcctg catggcctgc atggaagctt gcagtaaggg 3060 ctccgggtac ccaggcagat ggagaaagtg gtcaggacag acccagagga gggagactgg 3120 gctcagtttg gggagatcag aggttccctc agcccctcaa ccttacccat ttcccagaag 3180 cccaccctgg cctctcacct acacagagat gtcatcacca gcaaccccta cactttttct 3240 tttcctttga aaaaatgctg attgaggtta aatataccta tataatttat caactttacc 3300 atttttaagt gtaaaatcta gggatcataa atacctttat atgctgtgtg cggtggctca 3360 cgcctgtaat ctcagcattt tgagacgcca aggcaggtgg atcatttaaa atcaggggct 3420 ggagaccagc ctggccaaca tgggggaacc aatctttact aaaaagacaa aaaaaataaa 3480 attagccagg catggtgcca ggcacctata atcccagcaa cttgggaggc tgaggcggga 3540 gagtggctta aacccaggag gaggaggttg cagtgagctg agatcatgcc actgcactgc 3600 agtctggtga cacagagaga ctctgtctct aaataaataa ataaatactt ttatattctt 3660 cttttgttac cctccacccc ttccttccta acctctggta tccaccattc tactctctac 3720 cttcatgagg tccacctttt acatcctgca tgtgagtaag aaatggcaat ccttgtaatg 3780 acctccagtc catccatgtg gctgcaaatg acaggacgtt actctttgta tggatgagtt 3840 gtctccattg tgtgtatgta ctacattctc tctatccatt catccactga tgggcaggta 3900 ggttgactcc acatcttggc tactgtgaac agtgctggaa cagtcatggg agtgcagatg 3960 tcacttcaat acactgaagt ccttttcttt gcatttacac ccactagtgg aattgctaga 4020 tcctctggat gttctctttt taggttttgt tttatgcttt ttgttttttt gacatagcgt 4080 ttcactcttg ttgcccaagc tggagtgcaa tggcaccacc tgggctcact gcaacctcta 4140 cctccaggat tcaagtgatt ctccagcctc agcctcccga gtagttggga ttactggtgc 4200 ccgccaccac gcctggctga tttttgtatt tttagtagag acggggtttc accatgttag 4260 ccaggctggt ctcgaactct tgacctccag tgatctgccc acttcagcct cccaaggtgc 4320 tgggattaca agcgtgagcc acagtgccta atctcttttt agtttttaag gaacttccat 4380 attcttctcc tctgtaatgg ctgtattaat ttacattcct atcaacagtg tatcagggtt 4440 ctcctttctc caccaccttg ccaacatttg ttttgtctgt ctctgagata aaacccattg 4500 taatggggtg agatgatagc tcattgtgac ttcatttgca tttctctgat gattagtgat 4560 actgagcact ttttcatata tgcaatgtat atatgttcat ttgtatgttt tgttcattga 4620 gaaatgtctg ttcaggtctt ttactaattt tataattaaa ttattagttt tattgaggtg 4680 tttgagcttc ttttatattc tagttattaa tcccatctca gatgcatagt ttgcaaatat 4740 ttgctcccat tctgtgggtt gtctcttctt cacttcattg gttgcttcct ttgcggtgca 4800 gaagctgctt gatttgatat aatcccaatg gtctattttt ttgttgttgt tgtgattact 4860 tgtgtttttg aggttttaaa caaaatgtct tccctcagac aaatgtcctg gagcatttct 4920 ccagtgtttc cttttagaca tttaatggat tcaggtctta agtcattaat ccattttcat 4980 ctgatttttg tgtatggtga gaggtagagg tgcagtttca tccctctgca tgtagatatc 5040 cagttttccc tgcaccattt attgaaatga ctgtcctttc cagattgtag attcttcgaa 5100 cctttgtcaa agtccattgg atgtaaatgg gtggattaca tccgtgttct tcattctgct 5160 ccattgtttt atgtgctttt ctttatgcca atgtcatgtt gttttgctta ctacagctct 5220 gtaacatatt tttaagtcag gtagtgtgat gctcctgttt tctccttata ccttgaagtc 5280 tcaagatagt tggtgtcacc tacaatgatt atggagaatg ggatgccagg actcccaggg 5340 cccaacatta gataatagaa tgttggccat gaaccaacct caaagatttc cattgagtag 5400 aagacaggca tcctcattgc cacacctctc tcctgtccca tgttctagga aacccttcta 5460 gtagttggcc ttcacccact gaaccaagct tcaaaactgg taagtgaagg acccctctta 5520 tctctgcttt tggaaacctg gggaggtaga agccttggat tcaagcgttg gctcagcacc 5580 tgccagctct gtgattgtgg gcctgtcttc cattgtctct gaaccccaga cactccaaca 5640 gggaaaggga tctgggccca gcacagggct cagtgaaatc tcttaatctc taattttctg 5700 ctgctgagac ctcagggtag aaggatgagt gcaaatcaga cattcttctc aggaaaaatg 5760 ctgtgtttgt tctgcctgca ttcctaactg ggaggacaaa tgcctggggg cttgagaagg 5820 ggaaggaagg ggaacatttt tgagggtggt gtatttgtag agaagttcta cttgccaagg 5880 aatgagctcc tgtctgtcat gatccaaccc tggttgactt agtggaacaa gagctttgcg 5940 gtaagagaga acgtagttca tccgtgcaca tgacacttcc acttactcgt tcagccactg 6000 ccccatgctc agactgtgca gtgtggaacc ttttcctatg ttgccataac aaatttccac 6060 aagcttcgtg gatggaaacc acatttttaa aaaatatctc atggtgctgt agctcagaag 6120 tatgaaatgc atcatctcac tgggctaaaa tcaaggtgac agcaaggctg ccttccctct 6180 gaatgttcca ggcaagaatc tgcttcctca cttttcccag ctcctagagg ctcccacatt 6240 ccttggctcc tggtccccgt cttcctccct caaagtccac aaaggctggt cacgcctctc 6300 acacggcatc actcagaccc ttcttccttg tccacacctc tttctctgaa tgctgctctg 6360 ccttcttcct catcttttaa ggactttggc attctattgg aaacaccaag ataatccatc 6420 ataatttccc taaaatcatc taggataccc tccttttaag gttagctgat tagcaaccgt 6480 aattccatct gcaatctgca ttcctttttt ccatgtaaaa taacatattc acaagatatg 6540 gcgactagga caggaacatt ttggggtggg gcggcattct tatcctttcc acaaatggta 6600 aacaaggtgc atttggcctc tgctcttgga cactgatatt gcaaaggatt aaatgggagg 6660 gcagaaaatg aatgcaccag tggaccaata aatgaatgat ccattgggaa gcatctgtgc 6720 atgagaatga ttgattgatt ggttgttttt atgagacggt gtctccctct gtgccccagg 6780 ctggagtgca gtggcgggat ctcggctcac cgcaacctcc acctcccagg ttaaagcgat 6840 tctctacact cagcttcccg agaggctggg attacaccca tgtcccacca cgcctggcta 6900 attttttttt ggtatttttt ttttagtaca gacaaggttt taccatgttg cccaggctat 6960 ctcaaactcc caaccttaag ggatccgccc gtctcagcct cccaaagtgc tgagattaga 7020 ggcgtgagcc aaggcgccga gccgtatttt aaaagaaata atagataatg ctgagtgtat 7080 aatttcgggt gacagagaag ttctcactga tcaaataata cttgtgacct taatgaaaaa 7140 aatagatcaa cccctggaag attggcggaa ggattttcca cacagctgtc agccgtgaag 7200 gcacaaaggt gaaaacaatg ttatgtggaa ggaagaggct ctgcctgaaa tgctgggaat 7260 gacatgggga gaatgacaag acgactgtag agagacagag agcactctgg gtacacagga 7320 aactaaggag caacaaggag tgtgtgtttg acactcacag ccattggact tacctcgggg 7380 ctaactggga atccctacat gatgaatagt gactgacatg aaaataaggg aggcccaggt 7440 gcataactgg aatctaggag actgtggaaa aggcaattcc cgcccccctg gtgaaatgtg 7500 gtgctgattt agacactaaa tgaatgaaag atggacaaaa gatgtgtttg tgaggtagag 7560 taatttgcag ggagggcttg cctggtttga tttttcctaa ttgtttaatc ttcacttcat 7620 tgatttcttt ctgagattta tttttcctac atgtaaatca atacttggca gaggagtgag 7680 agatacatga ggggtggtgc aaaggaagag acctattata atataacaca caaggttctg 7740 aacggtggct cacacctgta acccaacatt ttgggaggct gaggaggctg gatcaagtga 7800 gatcaggagt tcgagatcag cctggacaac atggtgaaac cccatctcta ctaaatatac 7860 aaaaactagc tgggggtggt ggcgcatgcc tgtaatacca gctattcggg aagttgaaga 7920 aggagaatgg cttcaaccag ggagggagag gttacagtga gccaagatcg cgtcattgca 7980 ctgcacccta ggtgacagag tgagactcca tggcaaaaaa taaaaataaa gaataaataa 8040 atataatata acatacacga atgacaaagg cacaccaatt ccaatcatca tttttctatt 8100 tctctataat gacttctttg atcctttatc ctatccgtaa gaaaatcagg cgaaaacatc 8160 ttccttattt ggctttctgt gagcatgaga tcatatggaa aatgtgaaac ccaccagcac 8220 aggtcctgga atagagaacg tgatctgttc atggcacaaa acttgcccct tcacccaaat 8280 cccccacctc acccctactt ccaatcacat taatgataca gatagatcat ggggaggtaa 8340 aaactaatat tctttggagt tcagatcgta gactcagaga ccagtgccag cactatctcc 8400 tggtcacctt ttggagtaat tcacagaaag acaggctgta ttgaagcaac agatgatgga 8460 gggggtggtc tttcccccag actctcgggt ggaacagcag cctaatatct gactcccaag 8520 atgacaaaag tagcatgttg cccacgagct tcatcattat ttcctggctg tttgatataa 8580 gacagctcaa cctcacttat gttgatttca atgtcactgt tttttccttt tcttggagaa 8640 tgtaatttgt ttgagtcaag agggttgtgg atgtagaaac tgtaaagcac attcactgtg 8700 tatcaatccc agtccagtct tcccagagaa gactctaaac acctcccata ctgcacctgg 8760 gcctgtgcca atttctatca ctcaccatca ctccagggag acagaacaca cagggaatac 8820 attacatagg caggttcatt acttatagat aagcagcgag tgacaacaga aaccttcctt 8880 tcagggtgag ccagtccctc aaggctcaga aaaactgctc aggacacatg gagtcacttc 8940 atgtgcactg tagctggggg aagccagaaa gcagcccagc ctgggttttg taccctggag 9000 ccacagggaa cactcagcta aagcactgca tgatgttctc ctccaggaag aacaggaaga 9060 cagcccaggc tgttctgaga cgttcctcct gatctcagga tgttgctgtc ttagcctatt 9120 tttgttgcta taaaagaaca cttgagcctg ggtatcttct aaagaaaaga gatgtgtttg 9180 gctcactgat cggcacgctg tagtagaagc aggacactac catctatttc tggctgcggc 9240 ctcaggctgc tcccacactg acagaagaga agggggtcct gcgtgtgcag agaccacaga 9300 gatcacatgg caagagaggg agaaaggggg tgtgatggag cttccaagct ctttttaaga 9360 atcaactctc cagggtacta atagagggag aacttgctaa acccgtcctc tggggacagc 9420 attaatctat tcatgatgga tccaccccca tgaccaaaac acccctccca ataggcacaa 9480 cctcccacac tggggattaa atttcaaagt ggggtttgga ggggtcaaac attgaaacaa 9540 tagcagttgt atcatcagca cattctattg ttattatgaa aactataacg gagaaagcag 9600 gagaaagctg ggtctcccgc ctcgtgggtg cttgtcctaa agaggtgttt tatgtggttg 9660 cctggcaacc aagaaatgag agacaatcca caaagaggaa ctgctatggt tagcttctta 9720 ttggattctc atcttcctcc aggtatcgcc agacacctgc atgctgtgat taggtactca 9780 gtggccatca tcctcttcac catccttccc ttctttctcc ttcatcgctg gtgctccaaa 9840 aaaaaaagta agcctcacga agcagaggcc agagaactca gggccctgtg cggaagcagg 9900 atgggagcac gcaggtgtgt gttcctcact ggcaggaaag tctctggccc aaggcaggag 9960 ccagaggcag agctttctag agagagcacc agacaccctg cccctgcctt cagctcacag 10020 accattgcct gattgtgaac tgtatcctca cgtcccctgc agccactcac atccaggaga 10080 agattccatg acaggcagaa agtgggagat agaatcaatg ggatgggaac tgacagctat 10140 tcatggaatg gggtcttgca ctcagagaga tggaatgtct gagtctggct gttggcagct 10200 gagggacctc aggcacctat ggcctccccc tgtgtgttgg tatctgttca tgaaatgagg 10260 acccagaagt gccctcccag ctgttttgat tgcttccgtc tcctacagat gctgctgtaa 10320 tgaaccaaga gcctgcggga cacagaacag tgaacaggga ggtaggtcct cctagcccag 10380 cctcatggat acagtcttat tccctaatag tcctgaaaaa tgtgaacacc ctccctcact 10440 caggatttcc ctctctccag gactctgatg aacaagaccc tcaggaggtg acatacgcac 10500 agttggatca ctgcattttc acacagagaa aaatcactgg cccttctcag aggagcaaga 10560 gaccctcaac agataccagc gtgtgtatag aacttccaaa tgctgagccc agagcgttgt 10620 ctcctgccca tgagcaccac agtcaggcct tgatgggatc ttctagggag acaacagccc 10680 tgtctcaaac ccagcttgcc agctctaatg taccagcagc tggaatctga aggcgtgagt 10740 ctccatctta gagcatcact cttcctcaca ccacaaatct ggtgcctgtc tcttgcttac 10800 caatgtctaa ggtccccact gcctgctgca gagaaaacac actcctttgc ttagcccaca 10860 attctctatt tcacttgacc cctgcccacc tctccaacct aactggctta cttcctagtc 10920 tacttgaggc tgcaatcaca ctgaggaact cacaattcca aacatacaag aggctctctc 10980 ttaacacggc acttagacac gtgctgttcc accttccctc gtgctgttcc acctttcctc 11040 agactatttt tcagccttct ggcatcagca aaccttataa aatttttttg atttcagtgt 11100 agttctctcc tcttcaaata aacatgtctg ccttcat 11137 //