Dbfetch

Furin-like repeat

AccessionIPR006212; (Furin_repeat) matches 10313 proteins
FullNameFurin-like repeat
TypeRepeat
SignaturesPFAM: PF15913 Furin-like_2
SMART: SM00261 FU
Found inIPR005127; IPR006211; IPR016245; IPR016246; IPR020691;
Abstract

The furin-like cysteine rich region has been found in a variety of proteins from eukaryotes that are involved in the mechanism of signal transduction by receptor tyrosine kinases, which involves receptor aggregation [].

References
  1. Raz E, Schejter ED, Shilo BZ. (1991)
    Interallelic complementation among DER/flb alleles: implications for the mechanism of signal transduction by receptor-tyrosine kinases.
    Genetics 129: 191-201
    [PUBMED:1936959] [PUB00006268]
Database linksPDB: 1igr; PDB: 1ivo; PDB: 1m6b; PDB: 1mox; PDB: 1n8y; PDB: 1n8z; PDB: 1nql; PDB: 1p8j; PDB: 1s78; PDB: 1yy9; PDB: 2a91; PDB: 2ahx; PDB: 2hr7; PDB: 3b2u; PDB: 3b2v; PDB: 3be1; PDB: 3c09; PDB: 3h3b; PDB: 3i2t; PDB: 3ltf; PDB: 3ltg; PDB: 3mzw; PDB: 3n85; PDB: 3njp; PDB: 3p0y; PDB: 3p11; PDB: 3qwq; PDB: 3u2p; PDB: 3u7u; PDB: 3u9u; PDB: 3w11; PDB: 4hrl; PDB: 4hrm; PDB: 4hrn; PDB: 4krl; PDB: 4krm; PDB: 4kro; PDB: 4krp; PDB: 4leo; PDB: 4oga; PDB: 4p59; CATH: 2.10.220.10; CATH: 3.80.20.20; SCOP: b.18.1.20; SCOP: c.10.2.5; SCOP: g.3.9.1;
Taxonomy DistributionCaenorhabditis elegans: 6
Eukaryota: 2
OtherEukaryotes: 1006
PlastidGroup: 4
Bacteria: 1
PlastidGroup: 7
Eukaryota: 25
PlastidGroup: 25
Eukaryota: 6229
Eukaryota: 1393
Eukaryota: 7
Fungi: 12
Bacteria: 1
Eukaryota: 34
Bacteria: 10
Eukaryota: 2
Eukaryota: 1006
Eukaryota: 37
Eukaryota: 2
Chordata: 3229
Cyanobacteria: 1
Eukaryota: 10297
Fungi: 163
GreenPlants: 25
Metazoa: 5743
Nematoda: 467
OtherEukaryotes: 37
PlastidGroup: 1393
Arthropoda: 51
Bacteria: 2
Chordata: 30
GreenPlants: 25
Metazoa: 5698
OtherEukaryotes: 2
Chordata: 3142
Fungi: 145
Nematoda: 231
PlastidGroup: 34
Eukaryota: 1542
Metazoa: 3
OtherEukaryotes: 1542
PlastidGroup: 2
Eukaryota: 4
Fungi: 4
OtherEukaryotes: 2
Metazoa: 23
Eukaryota: 10
PlastidGroup: 10
OtherEukaryotes: 4
Eukaryota: 4
Arthropoda: 1497
Bacteria: 16
FruitFly: 253
Human: 76
Mouse: 47
Nematoda: 236
Metazoa: 19
Arthropoda: 1446
Bacteria: 1
Chordata: 57
Fungi: 13
Metazoa: 22