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EBI Dbfetch
Furin-like repeat
| Accession | IPR006212; (Furin_repeat) matches 4503 proteins
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| FullName | Furin-like repeat |
| Type | Repeat |
| Signatures | SMART:
SM00261 FU
|
| Found in | IPR005127; IPR006211; IPR009030; IPR016245; IPR016246; IPR020691; |
| Abstract |
The furin-like cysteine rich region has been found in a variety of proteins from eukaryotes that are involved in the mechanism of signal transduction by receptor tyrosine kinases, which involves receptor aggregation [].
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| Examples | SWISSPROT: P00533;
SWISSPROT: P04412;
SWISSPROT: P06494;
SWISSPROT: P23188;
SWISSPROT: P24348;
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| References |
- Raz E, Schejter ED, Shilo BZ. (1991)
Interallelic complementation among DER/flb alleles: implications for the mechanism of signal transduction by receptor-tyrosine kinases.
Genetics 129: 191-201
[PUBMED:1936959] [PUB00006268]
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| Database links | BLOCKS: IPB006212;
PDB: 1igr; PDB: 1ivo; PDB: 1m6b; PDB: 1mox; PDB: 1n8y; PDB: 1n8z; PDB: 1nql; PDB: 1p8j; PDB: 1s78; PDB: 1yy9; PDB: 2a91; PDB: 2ahx; PDB: 2dtg; PDB: 2hr7; PDB: 3b2u; PDB: 3b2v; PDB: 3be1; PDB: 3c09; PDB: 3h3b; PDB: 3i2t; PDB: 3ltg; CATH: 2.10.220.10; CATH: 3.80.20.20; SCOP: b.18.1.20; SCOP: c.10.2.5; SCOP: g.3.9.1; |
| Taxonomy Distribution | Caenorhabditis elegans: 5
Eukaryota: 2
OtherEukaryotes: 546
PlastidGroup: 4
Eukaryota: 11
PlastidGroup: 4
Eukaryota: 25
PlastidGroup: 25
Eukaryota: 2181
Eukaryota: 1167
Eukaryota: 4
Bacteria: 1
Eukaryota: 8
Bacteria: 2
Eukaryota: 546
Eukaryota: 26
Eukaryota: 2
Bacteria: 1
Arthropoda: 453
Bacteria: 4
Chordata: 1418
Eukaryota: 4499
FruitFly: 252
Fungi: 27
GreenPlants: 25
Metazoa: 2045
OtherEukaryotes: 26
PlastidGroup: 1167
Arthropoda: 6
Chordata: 32
GreenPlants: 25
Nematoda: 8
OtherEukaryotes: 2
PlastidGroup: 11
Chordata: 1357
Fungi: 27
PlastidGroup: 8
Arthropoda: 447
Chordata: 29
Metazoa: 9
Eukaryota: 523
Metazoa: 3
OtherEukaryotes: 523
PlastidGroup: 2
Eukaryota: 4
Metazoa: 15
Nematoda: 50
Human: 59
Mouse: 46
Nematoda: 58
Metazoa: 2027
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