Dbfetch
ID HLA06604; SV 1; standard; DNA; HUM; 9775 BP. XX AC HLA06604; XX SV HLA06604.1 XX DT 28-FEB-2011 (Rel. 3.4.0, Created, Version 1) DT 16-JAN-2024 (Rel. 3.55.0, Last Updated, Version 1) XX DE HLA-DPA1*01:03:01:02, Human MHC Class II sequence XX KW Human MHC; HLA; Class II; HLA-DPA1; Allele; HLA-DPA1*01:03:01:02; XX OS Homo Sapiens (human) OC Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates; OC Catarrhini; Hominidae; Homo. XX CC -------------------------------------------------------------------------- CC IPD-IMGT/HLA Release Version 3.55.0 CC -------------------------------------------------------------------------- CC Copyrighted by the IPD-IMGT/HLA Database, Distributed under the Creative CC Commons Attribution-NoDerivs License, see; CC http://www.ebi.ac.uk/ipd/imgt/hla/licence/ for further details. CC -------------------------------------------------------------------------- XX RN [1] RP 1-9775 RX PUBMED; 3036829. RA Gustafsson K, Widmark E, Jonsson AK, Servenius B, Sachs DH, Larhammar D, RA Rask L, Peterson PA; RT "Class II genes of the human major histocompatibility complex. Evolution of RT the DP region as deduced from nucleotide sequences of the four genes."; RL Journal of Biological Chemistry 262:8778-8786(1987). XX RN [2] RP 1-9775 RX PUBMED; 15140828. RA Stewart CA, Horton R, Allcock RJ, Ashurst JL, Atrazhev AM, Coggill P, RA Dunham I, Forbes S, Halls K, Howson JM, Humphray SJ, Hunt S, Mungall AJ, RA Osoegawa K, Palmer S, Roberts AN, Rogers J, Sims S, Wang Y, Wilming LG, RA Elliott JF, de Jong PJ, Sawcer S, Todd JA, Trowsdale J, Beck S; RT "Complete MHC haplotype sequencing for common disease gene mapping."; RL Genome Research 14:1176-1187(2004). XX RN [3] RP 1-9775 RX PUBMED; 35094503. RA Turner TR, Hayward DR, Gymer AW, Barker DJ, Leen G, Cambridge CA, RA Macpherson HL, Georgiou X, Cooper MA, Robinson J, Mayor NP, Marsh SGE; RT "Widespread non-coding polymorphism in HLA class II genes of International RT HLA and Immunogenetics Workshop cell lines."; RL HLA 99:328-356(2022). XX CC -------------------------------------------------------------------------- CC The sequence below is the official allele sequence as approved by the CC WHO Nomenclature Committee for Factors of the HLA System. CC Any cross references may differ from the sequence shown below. CC -------------------------------------------------------------------------- XX DR EMBL; AL645931; AL645931.7. DR EMBL; CR762479; CR762479.5. DR EMBL; KT716045; KT716045.1. DR EMBL; KT716052; KT716052.1. DR EMBL; M23903; M23903.1. DR EMBL; M23904; M23904.1. DR EMBL; MH753031; MH753031.1. DR EMBL; OU943340; OU943340.1. DR EMBL; OU943342; OU943342.1. DR EMBL; OU943353; OU943353.1. XX FH Key Location/Qualifiers FH FT source 1..9775 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT /ethnic="African descent, European, Undefined" FT /cell_line="BM15" FT /cell_line="BOLETH" FT /cell_line="BY01257" FT /cell_line="BY01264" FT /cell_line="DBB" FT /cell_line="MZ070782" FT /cell_line="PGF" FT /cell_line="SHJO" FT CDS join(524..623,4208..4453,4794..5075,5290..5444) FT /codon_start=1 FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*01:03:01:02" FT /product="MHC Class II HLA-DPA1*01:03:01:02 sequence" FT /translation="MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFVQ FT THRPTGEFMFEFDEDEMFYVDLDKKETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTL FT IQRSNHTQATNDPPEVTVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGV FT AESLFLPRTDYSFHKFHYLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTE FT TVLCALGLVLGLVGIIVGTVLIIKSLRSGHDPRAQGTL" FT UTR 1..523 FT exon 524..623 FT /number="1" FT intron 624..4207 FT /number="1" FT exon 4208..4453 FT /number="2" FT intron 4454..4793 FT /number="2" FT exon 4794..5075 FT /number="3" FT intron 5076..5289 FT /number="3" FT exon 5290..5444 FT /number="4" FT UTR 5445..9775 SQ Sequence 9775 BP; 2661 A; 2135 C; 1898 G; 3081 T; 0 other; ggtggacctg aaagaaagat taattatata ttttattaga tagcacattc attcttaatt 60 atcagcagaa tatttttgta aaatattgac aacataacat aaaacatgat ttaaaatata 120 gtgaccaaaa aacatcaaag atcatctgac tgtctgggat gggggtgggg ctcgggagaa 180 ggaacataat ggaaaacatt tgccgtcaga agaaggtgta acttatcttt ttacatctct 240 ttctctaact ctgaaaatga actgtgaact ggagctctct tgaccacgct ggtacctaaa 300 attctcccat ctcttcccca gcaccttcca gcgtcctctt tacccagcaa cagagaatgt 360 cagctctatg atttctctga taggtgaatc ccagccatgc tgattcctct ccacccattt 420 ccagtgctag aggcccacag tttcagtctc atctgcctcc actcggcctc agttcctcat 480 cactgttcct gtgctcacag tcatcaatta tagaccccac aacatgcgcc ctgaagacag 540 aatgttccat atcagagctg tgatcttgag agccctctcc ttggctttcc tgctgagtct 600 ccgaggagct ggggccatca agggtgagtg ctcaggagga cgcaggagcg tcggggtgag 660 tgatggggtg gttcacatca attgctgctt cagggatcac agattttagg ggctcattga 720 tctatctggt cctcatagtc tatgttccct ctggccctca taataataac agcaataaca 780 gccagaattt atgagactcc tgcatagttt ctttccccat ttacatctca caggaatctt 840 caatgaagat aatattccat tcatttagaa attattcctt ttatttagaa attattttga 900 aaaaactgaa gctcaaaaag atgaataagt tttccaaggt tacacagcag atcaacgagc 960 caagtttgaa gtccagaccc agctctgagg gtcatacact gccttcccca gattcctgca 1020 cacagtgacc tactatcagg gccctcctat ctctctggga tccccagcct ctatcttttg 1080 tggctgcttt acaggaactc cgagctatgg actctgcatt aggagacgaa gtgcaaagag 1140 tgtttctgta tcctccctct cttctaggac cctagggctc ttcctgggtc tttgtgggtg 1200 gtcacaagct ttcctctctc aagacagcag ggttgcatgg tcttgatagc cttgtgattc 1260 gggttctgag agattcagga ctgcaaggga ggcctagact tttgatagct gcaaggactc 1320 agccagagat ggaccgtagt gaatgctcct ttttcctgta gctgaaatca gggagaatga 1380 catcaagcct gtgcatgatg ctgtcattcc aaaatctagt gatggggaag gttagaatcc 1440 ataacgtaca agatgcacac tggcttcaga cagttttatt taagatgtgt agaataaaga 1500 ggaggtcagg ctgggtagaa ccagaagtat ctattgccct gttcgcggtc acctgagtta 1560 tttctaatgt tatgttataa taaacaccac aataggcttc tcttcataga tgcaaatact 1620 ttttagtatt cttggtagaa attcctaatg agctcagctg tctcttcagg gcttccctgc 1680 ccagtctctt aacatttaaa catgtcattt accttaaaaa cataagtgca aaccaactga 1740 taaaaaacaa ccttgccttc agtctgcatc ctgtcccaga gacactttct ttgtgtcctc 1800 acacgtggag ctaagcttct gacttgtctc tggtacatcc ctgaggatcc tctcatcttg 1860 gccatcagga acctctacag aaggtcaaat tcagtgggtt cttctcagtg cctctgactt 1920 gagttactaa taacatttgc actataatcc acttctttct gatgaactac cctgtcctta 1980 tttttctcct gtttacctgg atcctcctta tcatctttta aaccacctct taactatcat 2040 gttctctcat tataccctga gatctcggca attctgattt ttggcactct tcctggaaaa 2100 tcttatttaa cctgcacctg ccactaatga ctctcagttc tatggcctaa attcctctcc 2160 tgagaccacc cataatccac aaatatctat gtattatttc tccttagatg actttcaggt 2220 cttctaagtg caatagcccc acagtaaact cagtatcttc tcccggtcag gctgtcttcc 2280 ctgagagaag tggcttttgc cctgttttct gaatgcctac attgaagcca tctgttcccc 2340 aggaagcctt ccctgatgtg ctgtttggtc gcatcttgtg tatacctacg tatctgcact 2400 tatccttctg aacctgctgt tgtcctgtca cttgtgtttc cttctgtgac ttatacgcgt 2460 ctgcagaaca ggacgtatgt attattttta tttgggtatt tagcatctaa cagtgtttga 2520 catatagtag tcttttaata catatttttg tctgaatgga aatgatattt tgaagaaaaa 2580 taatctgttc catagctggc tgatctttgg actgcagaac ttgtgaaagt gttttttaaa 2640 aagcatttta aaaagtacaa gggacattca tgtattaaga agatgagttt ccaataactg 2700 ctagaggact ttgtgtcttt ttattttacc ctctttttcc tgatgagtcc tttgagtcct 2760 ttaaactgag gagcaagcta agtttcctag tgaaatacct ataggatttg ttttgtttag 2820 tttcaaatac cactctttgc ttggccactt actgtgtcag ggagtcattc tcagtgaaaa 2880 ataagacaca ggtcataccc tctagacact tacaattaca gtggcaagga gtcattctcc 2940 tgtcactgta agtggccaag cacagactgg gtccccacat gtcagggctg aaaactcaca 3000 gggaaatctg tgagttggga ggtgagagca gaagagtccc gtagttcctt ctcactctga 3060 tgcatttatc attctaaacc cagactttca catacacatt catcgttttc tttcatgata 3120 atagttgctt ttatcctctt atctttgcta attcttacaa actaataaag actaagaaac 3180 aaaataaatt aaatcctaca ggtgttccaa actcagcaat aatttctagt tggcctctaa 3240 aacaaaaatc aaaatataaa tgtaagaaaa gtttagaatg cttagtacct gtgtgatgaa 3300 ataatctgta cactaaaccc ccaagtcatg agtttaccta tacaacaaac ctgcacatgt 3360 actcctgaac ataaaataaa tgttgaaata tttttaaaaa ggaaacaaaa gtttggaaca 3420 aatgccaaaa taactgtact gtacttttga atttatatgc cccaaatgaa aaatattatc 3480 aacaaagcta tacattctac agtttcatgt tcataaacta agacagaaac tttaaaactg 3540 tcaagagccc taaaatttga aggatatttt cttcttcctc tcaattttgt atttttttct 3600 accttttcta taataagaaa aagaaaatgt ccattccccc acccccatga ctctaaaaac 3660 aattttacat ctgtgtcata gaaaaattaa gatcttaatg ggagagaaaa cctctctact 3720 agttccgcca gtagccgtat gaccttagca agttattaat atgtaacttc cctgcatttc 3780 cttacctgta aaatgtatga tatgtatttg cttcataggg ttattgtgac aattcagcga 3840 gtgaaatatg taaagtattt agaaggatgc ctggcacaag taagtgctca acaaatgtta 3900 gctgtcattg ttactattac tattgtgtag ggtcaggatg cccagacttt caaagaccag 3960 gaagcagctt gacttatcag tgataaactt ttcattttgt tctttgctcc tttcttttta 4020 taactgctca tctgctctgt attatttcct ttatggtgtt gctccttctt cttccccata 4080 tgtccttcct ttgacctctt accttcttcc tttttatatt cataagtctt tattcattct 4140 ctagctttga ccacttgcat attcaaactg acattttgtc gtgtttttct ctactgtctt 4200 tatgcagcgg accatgtgtc aacttatgcc gcgtttgtac agacgcatag accaacaggg 4260 gagtttatgt ttgaatttga tgaagatgag atgttctatg tggatctgga caagaaggag 4320 accgtctggc atctggagga gtttggccaa gccttttcct ttgaggctca gggcgggctg 4380 gctaacattg ctatattgaa caacaacttg aataccttga tccagcgttc caaccacact 4440 caggccacca acggtacgcc ctatctttgc ctcttcctct gtagcccaac tggaagggat 4500 gagagggcct ctctgccacc ctcagactag gaagcctaag tgccccctgc tgtgtgatcc 4560 tcttccccta gtggccatgg gctgatccca ctacagcaag ggcttgcatc ctctcttctc 4620 aggagagaga aaggtgagca gagtgaggct ggtcagtggt gtgatacccc tctctgtgat 4680 tcagagctgc cataaaatct aaggctgagg tagaggacca ccctccccta agaggtggag 4740 cctttgtgat tcatcccaga agaggggcct aacctggtgc tgtctccttc cagatccccc 4800 tgaggtgacc gtgtttccca aggagcctgt ggagctgggc cagcccaaca ccctcatctg 4860 ccacattgac aagttcttcc caccagtgct caacgtcacg tggctgtgca acggggagct 4920 ggtcactgag ggtgtcgctg agagcctctt cctgcccaga acagattaca gcttccacaa 4980 gttccattac ctgacctttg tgccctcagc agaggacttc tatgactgca gggtggagca 5040 ctggggcttg gaccagccgc tcctcaagca ctggggtatg caactgcttt tctctccata 5100 atctcctggc atcctctatt ccaaagacct ggtgtcctct gcaccagctt tccgcactgg 5160 ctgggtctca gtcctctcct cgtcctaaca tccaattaac tggtccataa ccttcaattc 5220 ccacaaccat cccaggccat caccaccctc actgcacctc ctgaccctat ctcttcattc 5280 ttcccccaga ggcccaagag ccaatccaga tgcctgagac aacggagact gtgctctgtg 5340 ccctgggcct ggtgctgggc ctagtcggca tcatcgtggg caccgtcctc atcataaagt 5400 ctctgcgttc tggccatgac ccccgggccc aggggaccct gtgaaatact gtaaaggtgg 5460 gaatgtaaag aggaggccct aggatttgta gaatgtaagg aagggaggaa aaattcaatc 5520 tgataagtgt tcattgatct tctaatgggt taaaagcatt cagccacata acaacaacaa 5580 caccgataac taactgagta gttaatatgg tcaggcgcta ttctgaggat ttacatttat 5640 taactcactt tattctcaca catagtcttt gaggtaggta ctattatttt cactatttca 5700 catgagagat acttacatct ttttacatac acagagactt taagcacttt gatcaagttc 5760 ccacagctat gaagtagtag ggctagcttc caatccagaa agtctggatc caagactgtt 5820 tatccactgt cctattcacc ctattttgtg aaggaaaaga ccaagttcaa attctccaga 5880 gtccattgcc aaataatgga gtcagatcta tatttctata cataattaca acacagtgtg 5940 gtgggtgcct gtaactactt actgtctcta cttggactca ttccatggca atgttcacac 6000 aaaaaatgcc cctccagaga tcttacaggt ttctatttat cataacactc accatgcttt 6060 atatttttat atgttttggg aattctctta gcattagaca gtgaacttcc atgcagatga 6120 ccacatctaa ttcattatta ttattgttat tcatgctgga cctcaggtac aaaaggttaa 6180 gaacttctca gttcattata tgatcatcat tggtgcctcc gagctctctc tctctccctt 6240 gatttatttg gtccctttta tctccagtcc ttactcccat atctaacctc ttacccctac 6300 ctcataggta aacattttaa tgaatttgat gtttcctttt atttgcatag atcctctgta 6360 atatgtagta gtgtccagtg tacatgtatt tttaattaac caaaatggca ttaaattata 6420 gatctaattt tgtacatcca gtttgtttct tccaaatctt ccatagtatt ttactttata 6480 tgtccatgca ttagtccatt ttgcattgct ataaaggaat atctgaagtt acctaattta 6540 cgaagaaaag agctttaaat ggctcacaga tctgcaggct gtacgcgaaa catggcacta 6600 gcatctgctt ctgttggggg attctggaag cttttactca tggtggaagg caagtggagc 6660 cagtgcatca catggtcata gagggagaaa gagacataga aagaggtgcc agcctctttt 6720 taacaaccag gtttcatgtg cactaataga gtgagaactc actcattacc cggagagggg 6780 acaaagccat tcatgagggt ctcctccatg attcaaatac ctcccaccag gccccacctg 6840 caacactggg gatcaatttt caacatgaga cttggaagtg acaaatatcc aaatcatatt 6900 aatccacata tctacattgc tcctgggata cctggatcat tcctggttct ctactattgc 6960 aagcaatgct tgtatctcac atggaactgc atatacatgt gggcctgacc tgcatccctg 7020 gaatgtatgt atcctagaaa ggggttgcag ggttgctgga gatgcagctc cttaatttga 7080 ctaaacactg ctcatcttct catcagaatg gctgtactca tctgaacttc ctttgtcagt 7140 actctaattg tcctgcaact cctaaatgga cttcaacact ggacattatc cagttttcta 7200 acttttgcca atttcatgtg cataaagaaa tatgctgttt tattttgcat ttctttaatt 7260 actaataatt ggggctataa ttaggactga ttagccactt gggggttcct tttctataaa 7320 ttgcctgttc acattcattg tccatttttg tactatgtgc ttccatcatt ttcttattga 7380 tttgcaggtg atccttatat agtcctgcta gtagtccctt gtcagtttta ggcattgcaa 7440 atgttttcct ctaatctgac ttctggcaac tgtctccttg gtttccttta ttgaagagaa 7500 atccttaata ttttgtaatg aagtccatca actgtatttt tgtttgtgtg tcttttttaa 7560 aagaagtctt ccctatactg agatatcaaa gatactctta aaacatctcc tacagtttta 7620 aatttcacat ttactacttt aattcatctg ggattcatct ttgtgtttga tggggatcat 7680 gttttatttt tctttatata atgggccagt gtgttcccac aactactaaa tagttcacct 7740 tttccccata ggttagtagt gtctcctttg ctatactgaa agctcccatt ataggtgggc 7800 ctgtgtctga gttccatctt gttccactgt tctgtttgtc tcttcttgtg ccagtgtcct 7860 agtattttga ttactatgac attgtagtgt gtgttagtat ccagtaggac aaattcttgt 7920 ttatttttct tagttcacac acatttataa ttatatctat aatgatttgt aacagagtga 7980 agtgaatgta gaatgtcaga tgttaagagg aagaatggaa aagagggctg ggactagggt 8040 gatgtagggg atgcacctgg cttaggtgca aaatttgggg gataccaaaa gaactcagta 8100 ataaatcata ttttaatgaa atatcttgaa aaggcaaaat taatgcaaag atacatgatt 8160 aacaaaacat ccaaagagga gtatttaaca aaaatggaga agcagagaag cagaagaatt 8220 aggagaatat gctgtcacat gagccaagga attaaagaat tcaggaagga ggaagtactg 8280 ctgtcagatg ttcaacagag gtcattttag aaaatttacc ttggtttttg aaatcctttc 8340 aaagagcagt atacacaatg tgagcaagta tccttcgttc attgccgtca ttgatatggt 8400 ttggatattt gtcccttcca attctcattc cagggttaag cttcttctct gccctcagta 8460 atgtggccct tccccttgtc tgtatatttt ggagacatga agcatgtggg atggcctcac 8520 agtcagctgg ggtttgaggg tgaaattcaa tgactttcgt gaactccttg gctcctatgt 8580 gctcttcacc tggaggacca gggcatgtgc agggatgacc accttctccc tgggacctga 8640 acagggcaga gaaatgggaa gctcgggtgc aaagggagtg gggaagatgg gtccgggctt 8700 acagtactga acccaggaat gacaataact gtgtgtgttg ctgcaggtga caaaatatct 8760 gaacagaaga ggacttagga gagatctgaa ctccagctgc cctacaaact ccatctcagc 8820 ttttcttctc acttcatgtg aaaactactc cagtggctga ctgaattgct gacccttcaa 8880 gctctgtcct tatccattac ctcaaagcag tcattcctta gtaaagtttc caacaaatag 8940 aaattaatga cactttggta gcactaatat ggagattatc ctttcattga gccttttatc 9000 ctctgttctc ctttgaagaa cccctcactg tcaccttccc gagaataccc taagaccaat 9060 aaatacttca gtatttcaga gcggggagac tctgagtcat tcttactgga agtctaggac 9120 caggtcacat gtgaatacta tttcttgaag gtgtggtttc aacctctgtt gccgatgtgg 9180 ttactaaagg ttctgatccc acttgaacgg aaaggtctga ggatattgat tcagtcctgg 9240 gtttttccct aactacagga tagggtgggg tagagaaagg atatttgggg gaaattttac 9300 ttggatgaag attttcttgg atgtagtttg aagactgcag tgtttgaagt ctctgaggga 9360 agagatttgg tctgtctgga tcaagatttc aggcagatta ggattccatt cacagcccct 9420 gagcttcctt cccaaggctg tattgtaatt atagcaatat ttcatggagg atttttctac 9480 atgataaact aagagccaag aaataaaatt tttaaaatgc cctaattcat tgcaattttt 9540 accagccata gtcactccat gtgggagaac ttaaatcatg attaccagag ctttcaaagg 9600 tttgagaata gtgatgatta tgaagaaaaa tatcttattt gagcaaggat tttgtttctt 9660 tatgagtgtt cattagatat tacgatgaaa aaagcatgaa atggtaaaaa ttcagataaa 9720 tataaaaaca tgttctctag ttttttttaa gttaaaaaag gaattgttta aagta 9775 //