Dbfetch
ID HLA02990; SV 2; standard; DNA; HUM; 3983 BP. XX AC HLA02990; XX SV HLA02990.2 XX DT 31-JUL-2007 (Rel. 2.19.0, Created, Version 1) DT 16-JAN-2024 (Rel. 3.55.0, Last Updated, Version 2) XX DE HLA-B*07:436, Human MHC Class I sequence XX KW Human MHC; HLA; Class I; HLA-B; Allele; HLA-B*07:436; XX OS Homo Sapiens (human) OC Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates; OC Catarrhini; Hominidae; Homo. XX CC -------------------------------------------------------------------------- CC IPD-IMGT/HLA Release Version 3.55.0 CC -------------------------------------------------------------------------- CC Copyrighted by the IPD-IMGT/HLA Database, Distributed under the Creative CC Commons Attribution-NoDerivs License, see; CC http://www.ebi.ac.uk/ipd/imgt/hla/licence/ for further details. CC -------------------------------------------------------------------------- XX RN [1] RP 1-3983 RX PUBMED; 19744147. RA Anholts JDH, Aneq M, Dirks HLJM, Tas A, Verduyn W, Oudshoorn M; RT "Thirty-six novel HLA alleles: 7 HLA-A, 11 HLA-B, 15 HLA-C and HLA-DRB1."; RL Tissue Antigens 74:424-428(2009). XX CC -------------------------------------------------------------------------- CC The sequence below is the official allele sequence as approved by the CC WHO Nomenclature Committee for Factors of the HLA System. CC Any cross references may differ from the sequence shown below. CC -------------------------------------------------------------------------- XX DR EMBL; AM746337; AM746337.1. DR EMBL; OU242030; OU242030.1. DR EMBL; OX421031; OX421031. XX FH Key Location/Qualifiers FH FT source 1..3983 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT /ethnic="European, Undefined" FT /cell_line="22006489" FT /cell_line="AN300701" FT /cell_line="LUMC-B1" FT CDS join(285..357,486..755,1001..1276,1851..2126,2231..2347, FT 2789..2821,2928..2971) FT /codon_start=1 FT /gene="HLA-B" FT /allele="HLA-B*07:436" FT /product="MHC Class I HLA-B*07:436 sequence" FT /translation="MLVMAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPR FT FISVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRN FT LRGYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTA FT AQITQRKWEAAREAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHE FT ATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRY FT TCHVQHEGLPKPLTLRWEPSSQSTIPIVGIVAGLAVLAVVVIGAVVATVMCRRKSSGGK FT GGSYSQAASSDSAQGSDVSLTA" FT UTR 1..284 FT exon 285..357 FT /number="1" FT intron 358..485 FT /number="1" FT exon 486..755 FT /number="2" FT intron 756..1000 FT /number="2" FT exon 1001..1276 FT /number="3" FT intron 1277..1850 FT /number="3" FT exon 1851..2126 FT /number="4" FT intron 2127..2230 FT /number="4" FT exon 2231..2347 FT /number="5" FT intron 2348..2788 FT /number="5" FT exon 2789..2821 FT /number="6" FT intron 2822..2927 FT /number="6" FT exon 2928..2971 FT /number="7" FT UTR 2972..3983 SQ Sequence 3983 BP; 754 A; 1139 C; 1198 G; 892 T; 0 other; gatcaggacg aagtcccagg tcccggacgg ggctctcagg gtctcaggct ccgagggccg 60 cgtctgcaat ggggaggcgc agcgttgggg attccccact cccctgagtt tcacttcttc 120 tcccaacttg tgtcgggtcc ttcttccagg atactcgtga cgcgtcccca cttcccactc 180 ccattgggta ttggatatct agagaagcca atcagcgtcg ccgcggtccc agttctaaag 240 tccccacgca cccacccgga ctcagagtct cctcagacgc cgagatgctg gtcatggcgc 300 cccgaaccgt cctcctgctg ctctcggcgg ccctggccct gaccgagacc tgggccggtg 360 agtgcgggtc gggagggaaa tggcctctgc cgggaggagc gaggggaccg caggcggggg 420 cgcaggacct gaggagccgc gccgggagga gggtcgggcg ggtctcagcc cctcctcacc 480 cccaggctcc cactccatga ggtatttcta cacctccgtg tcccggcccg gccgcgggga 540 gccccgcttc atctcagtgg gctacgtgga cgacacccag ttcgtgaggt tcgacagcga 600 cgccgcgagt ccgagagagg agccgcgggc gccgtggata gagcaggagg ggccggagta 660 ttgggaccgg aacacacaga tctacaaggc ccaggcacag actgaccgag agagcctgcg 720 gaacctgcgc ggctactaca accagagcga ggccggtgag tgaccccggc ccggggcgca 780 ggtcacgact ccccatcccc cacgtacggc ccgggtcgcc ccgagtctcc gggtccgaga 840 tccgcctccc tgaggccgcg ggacccgccc agaccctcga ccggcgagag ccccaggcgc 900 gtttacccgg tttcattttc agttgaggcc aaaatccccg cgggttggtc ggggcggggc 960 ggggctcggg ggactgggct gaccgcgggg ccggggccag ggtctcacac cctccagagc 1020 atgtacggct gcgacgtggg gccggacggg cgcctcctcc gcgggcatga ccagtacgcc 1080 tacgacggca aggattacat cgccctgaac gaggacctgc gctcctggac cgccgcggac 1140 acggcggctc agatcaccca gcgcaagtgg gaggcggccc gtgaggcgga gcagcggaga 1200 gcctacctgg agggcgagtg cgtggagtgg ctccgcagat acctggagaa cgggaaggac 1260 aagctggagc gcgctggtac caggggcagt ggggagcctt ccccatctcc tataggtcgc 1320 cggggatggc ctcccacgag aagaggagga aaatgggatc agcgctagaa tgtcgccctc 1380 cgttgaatgg agaatggcat gagttttcct gagtttcctc tgagggcccc ctcttctctc 1440 tagacaatta aggaatgacg tctctgagga aatggagggg aagacagtcc ctagaatact 1500 gatcaggggt cccctttgac ccctgcagca gccttgggaa ccgtgacttt tcctctcagg 1560 ccttgttctc tgcctcacac tcagtgtgtt tggggctctg attccagcac ttctgagtca 1620 ctttacctcc actcagatca ggagcagaag tccctgttcc ccgctcagag actcgaactt 1680 tccaatgaat aggagattat cccaggtgcc tgcgtccagg ctggtgtctg ggttctgtgc 1740 cccttcccca ccccaggtgt cctgtccatt ctcaggctgg tcacatgggt ggtcctaggg 1800 tgtcccatga gagatgcaaa gcgcctgaat tttctgactc ttcccatcag accccccaaa 1860 gacacatgtg acccaccacc ccatctctga ccatgaggcc accctgaggt gctgggccct 1920 gggcttctac cctgcggaga tcacactgac ctggcagcgg gatggcgagg accaaactca 1980 ggacaccgag cttgtggaga ccagaccagc aggagataga accttccaga agtgggcagc 2040 tgtggtggtg ccttctggag aagagcagag atacacatgc catgtacagc atgaggggct 2100 gccgaagccc ctcaccctga gatggggtaa ggagggggat gaggggtcat atctcttctc 2160 agggaaagca ggagcccttc tggagccctt cagcagggtc aggacccctc atcttcccct 2220 cctttcccag agccatcttc ccagtccacc atccccatcg tgggcattgt tgctggcctg 2280 gctgtcctag cagttgtggt catcggagct gtggtcgcta ctgtgatgtg taggaggaag 2340 agctcaggta gggaaggggt gaggggtggg gtctgggttt tcttgtccca ctgggggttt 2400 caagccccag gtagaagtgt tccctgcctc attactggga agcagcatcc acacaggggc 2460 taacgcagcc tgggaccctg tgtgccagca cttactcttt tgtgcagcac atgtgacaat 2520 gaaggacgga tgtatcacct tgatggttgt ggtgttgggg tcctgattcc agcattcatg 2580 agtcagggga aggtccctgc taaggacaga ccttaggagg gcagttggtc caggacccac 2640 acttgctttc ctcgtgtttc ctgatcctgc cttgggtctg tagtcatact tctggaaatt 2700 ccttttggtt ccaagacgag gaggttcctc taagatctca tggccctgct tcctcccagt 2760 cccctcacag gacattttct tcccacaggt ggaaaaggag ggagctactc tcaggctgcg 2820 tgtaagtggt gggggtggga gtgtggagga gctcacccac cccataattc ctcctgtccc 2880 acgtctcctg cgggctctga ccaggtcctg tttttgttct actccagcca gcgacagtgc 2940 ccagggctct gatgtgtctc tcacagcttg aaaaggtgag attcttgggg tctagagtgg 3000 gcgggggggc ggggaggggg cagaggggaa aggcctgggt aatggagatt ctttgattgg 3060 gatgtttcgc gtgtgtggtg ggctgttcag agtgtcatca cttaccatga ctaaccagaa 3120 tttgttcatg actgttgttt tctgtagcct gagacagctg tcttgtgagg gactgagatg 3180 caggatttct tcacgcctcc cctttgtgac ttcaagagcc tctggcatct ctttctgcaa 3240 aggcacctga atgtgtctgc gtccctgtta gcataatgtg aggaggtgga gagacagccc 3300 acccccgtgt ccactgtgac ccctgttccc atgctgatct gtgtttcctc cccagtcatc 3360 tttcttgttc cagagaggtg gggctggatg tctccatctc tgtctcaact ttatgtgcac 3420 tgagctgcaa cttcttactt ccctactgaa aataagaatc tgaatataaa tttgttttct 3480 caaatatttg ctatgagagg ttgatggatt aattaaataa gtcaattcct ggaatttgag 3540 agagcaaata aagacctgag aaccttccag aatctgcatg ttcgctgtgc tgagtctgtt 3600 gcaggtgggg tgtggagaag gctgtagggg gccgagtgtg gacggggcct gtgcccattt 3660 ggtgttgagt ccatcatggg ctttatgtgg ttagtcctca gctgggtcac cttcactgct 3720 ccattgtcct tgtcccttca gtggaaactt gtccagcggg agctgtgacc acagaggctc 3780 acacatcgcc cagggcggcc cctgcacacg ggggtctctg tgcattctga gacaaatttt 3840 cagagccatt cacctcctgc cctgcttcta gagctccttt tctgctctgc tcttctgccc 3900 tctctccctg ccctggttct ggtgatcttg gtgctgaatc caatcccaac tcatgaatct 3960 gtaaagcaga gtctaattta gac 3983 //