Dbfetch
ID HLA02136; SV 3; standard; DNA; HUM; 7480 BP. XX AC HLA02136; XX SV HLA02136.3 XX DT 22-MAR-2005 (Rel. 2.9.0, Created, Version 1) DT 16-JAN-2024 (Rel. 3.55.0, Last Updated, Version 3) XX DE HLA-DQB1*02:04, Human MHC Class II sequence XX KW Human MHC; HLA; Class II; HLA-DQB1; Allele; HLA-DQB1*02:04; XX OS Homo Sapiens (human) OC Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates; OC Catarrhini; Hominidae; Homo. XX CC -------------------------------------------------------------------------- CC IPD-IMGT/HLA Release Version 3.55.0 CC -------------------------------------------------------------------------- CC Copyrighted by the IPD-IMGT/HLA Database, Distributed under the Creative CC Commons Attribution-NoDerivs License, see; CC http://www.ebi.ac.uk/ipd/imgt/hla/licence/ for further details. CC -------------------------------------------------------------------------- XX RN [1] RP 1-7480 RX PUBMED; 19539002. RA Cordovado SK, Hancock LN, Hendrix M, Greene CN, Mueller PW; RT "Novel human leukocyte antigen class I and class II alleles identified by RT sequence-based typing in the Genetics of Kidneys in Diabetes (GoKinD) study RT population."; RL Human Immunology 70:747-749(2009). XX CC -------------------------------------------------------------------------- CC The sequence below is the official allele sequence as approved by the CC WHO Nomenclature Committee for Factors of the HLA System. CC Any cross references may differ from the sequence shown below. CC -------------------------------------------------------------------------- XX DR EMBL; AH013029; AH013029.2. DR EMBL; AY333121; AY333121.1. DR EMBL; AY333122; AY333122.1. DR EMBL; LR777693; LR777693.1. DR EMBL; LR777695; LR777695.1. DR EMBL; LT575593; LT575593.1. XX FH Key Location/Qualifiers FH FT source 1..7480 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT /ethnic="European, Undefined" FT /cell_line="AN00119" FT /cell_line="CDC111703" FT /cell_line="DKMS-LSL_ID15050395" FT /cell_line="DKMS-LSL_ID15134647" FT CDS join(526..634,2073..2342,5232..5513,6030..6140,7261..7274) FT /codon_start=1 FT /gene="HLA-DQB1" FT /allele="HLA-DQB1*02:04" FT /product="MHC Class II HLA-DQB1*02:04 sequence" FT /translation="MSWKKALRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKG FT MCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKR FT AAVDRVCRHNYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRW FT FRNDEEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRA FT QSESAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQKGLLH" FT UTR 1..525 FT exon 526..634 FT /number="1" FT intron 635..2072 FT /number="1" FT exon 2073..2342 FT /number="2" FT intron 2343..5231 FT /number="2" FT exon 5232..5513 FT /number="3" FT intron 5514..6029 FT /number="3" FT exon 6030..6140 FT /number="4" FT intron 6141..6625 FT /number="4" FT exon 6626..6649 FT /number="5" FT /pseudo FT intron 6650..7260 FT /number="5" FT exon 7261..7274 FT /number="6" FT UTR 7275..7480 SQ Sequence 7480 BP; 1896 A; 1740 C; 1780 G; 2064 T; 0 other; ttctaagaac tttgctcttt tcaccaaaac ttaaggctcc tcagggtgtg tctaagacaa 60 cagcagtaaa aatgtctatg acagcaattt tctctcccct gaaatatgat ccccacttaa 120 tttgccctat tgaaagaatc ccaagtataa gaacaactgg tttttaatca atattacaaa 180 gatgtttact gttgaatcgc atttttcttt ggcttcttaa aatcccttag gcattcaatc 240 ttcagctctt ccataattga gaggaaattt tcacctcaaa tgttcatcca gtgcaattga 300 aagacgtcac agtgccaggc actggattca gaaccttcac aaaaaaaaaa tctgcccaga 360 gacagatgag gtccttcagc tccagtgctg attggttcct ttccaaggga ccatccaatc 420 ctaccacgca tggaaacatc cacagatttt tattctttct gccaggtaca tcagatccat 480 caggtccgag ctgtgttgac taccactttt cccttcgtct caattatgtc ttggaaaaag 540 gctttgcgga tccccggagg ccttcgggca gcaactgtga ccttgatgct gtcgatgctg 600 agcaccccag tggctgaggg cagagactct cccggtaagt gcagggcagc tgctctccag 660 agccgctact ctgggaacag gctctccttg ggctggggta cggggatggt gatctccata 720 atctcggaca caatctttta tcaacatttc ctctgttttg ggaaagagag ctatgttgca 780 tttccattta tcttttaatg atgaagtgag gacaatccaa tcccatccta caggcttaag 840 cctggaagag gaggagagag gagagaaaag aggagacaaa gtgttcattt actaccagtg 900 ataggacaaa gtgagcatgg ggttattttt gaagatatga atttctccaa agacacagca 960 ggatttgcca tttaggcgtg tcccaagact tgcctggact aaatattatg atttcctgca 1020 ttgggaaatg caaggcagca atggtgtctg tagtctccgt atttggggaa aagttgtctg 1080 tattcctgac ccagtggagc gtttgtggag gcaaaatctt ggtactgagg gaagctgact 1140 ggctgaccac agaaagagag ccttcaggtt tcactgattt atgggcaaat ggtgacctga 1200 gtgggattca gatacccgag ttgatgatgg actaaattta gtagaaagga ggatgtaaag 1260 aagggaaata acacatactg tgaaaccact catttcagac acagaacaat actttacata 1320 aattctctct cactccttct aacatcctgt gtgtagatat catgattttc ttttacacaa 1380 ttatacttgt gatatggata ttctgttaca taaactgccc gggctggtga ctgccacagt 1440 ttaatgggaa tctagtttat caaattcaaa agcttgtgct ctttcggtga ataaatgttt 1500 ctttctagga ctcagagatc taggactccc ttctttctaa cacagacgtg agtgaacctc 1560 acagggcact tgggagggta aatccaggca tgggaaggaa ggtattttac ccagggacca 1620 agagaatagg cgtatcggaa gaggacaggt ttaattcctg gacctgtctc gtcattccct 1680 tgaactgtca ggtttatgtg gataacttta tctctgaggt acccaggagc tccatggaaa 1740 atgagatttc atgcgagaac gccctgatcc ctctaagtgc agaggtccat gtaaaatcag 1800 cccgactgcc tcttcacttg gttcacaggc cgagacaggg acagggcttt cctccctttc 1860 ctgcctgtag gaaggcggat tcccgaagac ccccgagagg gcgggcaggg ctgggcagag 1920 ccgccgggag gatcccaggt ctgcagcgcg aggcacgggc cggcgggaac ttgtggtcgc 1980 gcgggctgtt ccacagctcc gggccgggtc agggtggcgg ctgcgggggc ggacgggctg 2040 ggccgcactg actggccggt gattcctcgc agaggatttc gtgtaccagt ttaagggcat 2100 gtgctacttc accaacggga cagagcgcgt gcgtcttgtg agcagaagca tctataaccg 2160 agaagagatc gtgcgcttcg acagcgacgt gggggagttc cgggcggtga cgctgctggg 2220 gctgcctgcc gccgagtact ggaacagcca gaaggacatc ctggagagga aacgggcggc 2280 ggtggacagg gtgtgcagac acaactacca gttggagctc cgcacgacct tgcagcggcg 2340 aggtgagcgg cgtcgcccct ctgcgaggcc cacccttggc cccaagtctc tgcgccagga 2400 ggggcgaagg gtcgtggcct ctggaacctg agccccgttt gttccacccc agaggacagg 2460 aggcagcggc gagagtggtg ggggcaggtg catcggaggt gcggggacct agggcagagc 2520 agggggacag gcagagttgg ccaggctgcc tagtgtcgcc ccagcctacc cgttcgtcgg 2580 ccttgtcctc tgctctgcat gttcttgcct cgtgccttat gcatttgcct ccttttgcct 2640 tacctttgct aagcagctct ctctgctcag aatgcccgcc ctcttcccct gcccgcccgc 2700 ccgccccact agcactgccc cacccagcaa ggcccacgtg cacagctctt gcagcaggaa 2760 gcttcaggct tagcctggtg gagttagggc tgttccacaa ctgcgcgcag gacattcagc 2820 aattacagtt gtgaaataag atattttaac ttttggcttc aaatcattat tcatcgtaat 2880 tctgttttct taaatggctc tcattcatgg cagagatctt tgaggtgagg gtgttttaat 2940 cattgcatgc ctagtacctg acacattgac tggtatgtgg tgtgagctca atgatcttct 3000 gttaaattaa tgaataaatg tactcagctg cccatccact taggctcaag aaaaaaaaag 3060 aggtaaacag agccttaaaa atggacttta ttaattattt tctataattt tgcttaatgc 3120 tttaaagtaa actcttattg acttggatct taatagagtt tgtgaataca aaatctgagg 3180 aaaaaagttt ttgctaaaaa taaaaacaac gcttgaaaga tattgtaagg cagtttaaat 3240 ttcttttctt ttcttttttt tttttttttg agacggattc tcactctgtc gcccaggccg 3300 gagtgcagtg gcgcgatctc ggctcactgc aagctccgcc tcccgggttc acgccattct 3360 cctgcctcag cctcctgagt aggtgggatt acaggcgcgt gccaccacgc ccggctaatt 3420 tttttgtatt tttagtagag gcggggtttc accgtgttag ccaggatggt ctggatctcc 3480 tgacctcatg atccgcccgc ctcggcctcc caaagtgctg ggattacagg tgtgagccac 3540 agtgcccggc cggcactttt aatttcttag aaaagctgaa caaatggcac aatgcaaaga 3600 gcaaaagttt tggaataaat agattgaagc cattaaatta ttggataaaa atagtttcgg 3660 gttgcttttg gcctaggttc tcccctcccc ccatgactat ccacttcagg aataaacatt 3720 ctgaaagtca attttaccca tttagtgagc atttatttct agacagttgc cttatcaaat 3780 accatctatg ttacgtcatt taatctcaca gttacttgtg catcagagat tagcatcacc 3840 actttatata ttggtacatg ataaacactt tattggtcat ggatggggag atggtcactg 3900 taggctaata ttggtacatg ataaacactt taagtaatca gcccataatt gctcaccaag 3960 accttaagcc tcccaaagta cacaacattc tttgtgttct tcactacaca tccatagagt 4020 ctaagggacg taaagcctcg ttaaagccag ttttgaccag aagcagcaat gagtctattc 4080 ctgtgtgttt tccatgttaa tgggacaaaa tgatactttc aaggcattga aaattcatga 4140 ttaatcaatc cctagtctga ccccagtgtt atctatgcag gtttgcaaaa cctttagttt 4200 acttaatact cccttgcctt cttttgattc acatcctaat gccagcaaat acttatgttt 4260 ttgctatttc agttccattt ccataaaatt tattttatca tcttttctca taaatttatg 4320 ccctctattt ttactcccaa tctgtttaag atgaacaaat cttataaggc cacatagctg 4380 actgttattt ctgttggact ccaggaagga gaacctaaag aaaagttcaa gtccaagcag 4440 aaaccgtgat ttcttccaga tgatggctca tgagtgccat ttaattgggg tgccacctgg 4500 tgacctcagc aaatcccagc tatatttatg tgttcacatt acaggatcat taacccagac 4560 cgaccactgc acagatctca gaatattttc tatggagaac atacataata atgcctgatt 4620 tcagaagaag aaagtaattc tcaatagcaa ggggatggag tagggtagac agctgtaatt 4680 aaactcactt gtgtgataaa aagaaattaa ggaaaaaaga aaatgagaga acatattact 4740 aaataaagaa agcatacatt aaatatttac tatagtttca cactaagaga ataaaggaaa 4800 tgcaataaag tggcctgaaa ggtaaaggat gagatgtgta aaggggtgta gtatttttac 4860 tatgagcagc aatctgagaa gataaaggaa tcgagttacg ggcaaacatg atgtttgatc 4920 agtgttattt gttttcaagg cctgcctaaa tttttttcaa atattacaaa cttttgaaat 4980 aacattcttt ttgttttttg ctgtctgtta ctaggttgca cattttataa aggcagggac 5040 catggtatgt tgtttgtctt tggattctca gtgattgtta tatttatatt tgttgaagga 5100 accttaatcc aagacttgga ctccaagtat ctttccactc tggttccaag gagggacctt 5160 cctcacagca ggcatgctgt gtggtctcac atctcactcc tatatctttc cctgtctgtt 5220 actgccctca gtggagccca cagtgaccat ctccccatcc aggacagagg ccctcaacca 5280 ccacaacctg ctggtctgct cggtgacaga tttctatcca gcccagatca aagtccggtg 5340 gtttcggaat gacgaggagg agacagctgg cgttgtgtcc acccccctta ttaggaatgg 5400 tgactggacc ttccagatcc tggtgatgct ggaaatgact ccccagcgtg gagacgtcta 5460 cacctgccac gtggagcacc ccagcctcca gagccccatc accgtggagt ggcgtaaggg 5520 gatattgagt ttctgttact gtgggcccca caagacaaag gacagagctc cttctgaccc 5580 atcccttccc atctcttatc cctgatgtca ctgctgagct gggaatcaca ggagactaga 5640 gcacctctag ttccatggcg agtgcatcag aagaatcctg atctcatcac ctttccagat 5700 gctagggaaa ttactctaca tactgttgct ctggatccca gtcctgattg ctctgaggaa 5760 ctgattatta gggctggtga ctgggatctt agggtctaag tttatggatg agttcctgag 5820 gagtggagat ctgcttcccc actctgtcac ctactcactg tatccaagga cctattggct 5880 ggcctttccc tcccttaggg gtggtctgaa tggagaacta ggttcctttg atgccttcac 5940 ctcctgcatc tcagactgga cttcagctcc tcatcaggga aactatgggg tatggggaca 6000 aacactgaca ctcaggctct gcttctcagg ggctcaatct gaatctgccc agagcaagat 6060 gctgagtggc attggaggct tcgtgctggg gctgatcttc ctcgggctgg gccttatcat 6120 ccatcacagg agtcagaaag gtgaggaacc ccaggggaaa aggggaagat ggcctgtgac 6180 ccagaccctc tgttcagaga ggtcctgtct ctagatgtag ctctttcctc ctgaccctga 6240 gaggaagaaa gctgagctgg aagtggaagg agacaggaca aggttggagg aggcattgga 6300 atctgatttt actagctgaa gggtagccct gtcacagagc tgactgatag agcttattcc 6360 agggcatcct taccattcat cattgtctca ctggctcctt tccaaaaact tcctccatta 6420 agagggtcag agcctcggcc tccttgcctt ctagtgacaa tttcctttat tttaggggat 6480 tttaaattag ggtgcttaag gacttgaaga acatgaatgg gaagagaata taactctaat 6540 taagtcacat gtgtcatttt cctttggggt gagagagtgg ctgttcatgt aatgagacct 6600 ttctctgcat aacttccttt tgtaagacct caagggcctc caccagcagg taatatttca 6660 gccgtgatcc agtgtgggga gggcacaggt gtaagaggga agagcatgag ctgagtgtac 6720 ctgacagtag tggtctctgt tcatggtata tttgctgcta tgaggatcaa gacttagggg 6780 tgaagtttgc cagtttctag gaatctccag aggttgttcc ccagaaccaa gccttaactt 6840 tggtggtatc ttcctgttaa atgtggagcc agaaccacgg cttaaatgtt agacactagg 6900 atgatgccca ctttgtgcca catgatggtg gctactgcct gtaggcattt tccagtgact 6960 gaaagaggct gctagtggta gggatgaggt atcatccaat ttcctaaaaa gattgaaccc 7020 ttcatattca ccagaagagt aacagctgtt cccccacctc ccacacatct gcatcaagct 7080 gaagttctgt gtcttcatga gctgatttca cctttgcaca gatcttgggg gaggtgatga 7140 caatacactc tggacctcag ctttgtctgt ctgaagctgc aggaggcccc tgaggggtgg 7200 ggaagatggc aggcccacca gcgtaccctg tgctgatcat ccctcttctc tcttcttcag 7260 ggctcctgca ctgactcctg agactatttt aactgggatt ggttatcact tttctgtaac 7320 gcctgcttgt ccctgcccag aattcccagc tgtctgtgtc agcctgtccc cctgagatca 7380 gagtcctaca gtggctgtca cgcagccacc aggtcatctc ctttcatccc caccttgagg 7440 cggatggctg tgaccctact tcctgcactg acccacagcc 7480 //