Dbfetch
ID HLA02050; SV 1; standard; DNA; HUM; 11466 BP. XX AC HLA02050; XX SV HLA02050.1 XX DT 13-DEC-2004 (Rel. 2.8.0, Created, Version 1) DT 16-JAN-2024 (Rel. 3.55.0, Last Updated, Version 1) XX DE HLA-DPB1*107:01, Human MHC Class II sequence XX KW Human MHC; HLA; Class II; HLA-DPB1; Allele; HLA-DPB1*107:01; XX OS Homo Sapiens (human) OC Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates; OC Catarrhini; Hominidae; Homo. XX CC -------------------------------------------------------------------------- CC IPD-IMGT/HLA Release Version 3.55.0 CC -------------------------------------------------------------------------- CC Copyrighted by the IPD-IMGT/HLA Database, Distributed under the Creative CC Commons Attribution-NoDerivs License, see; CC http://www.ebi.ac.uk/ipd/imgt/hla/licence/ for further details. CC -------------------------------------------------------------------------- XX RN [1] RP 1-11466 RX PUBMED; 16189666. RA Reinders J, Rozemuller EH, van Gent R, Arts-Hilkes YH, van den Tweel JG, RA Tilanus MG; RT "Extended HLA-DPB1 polymorphism: an RNA approach for HLA-DPB1 typing."; RL Immunogenetics 57:790-794(2005). XX RN [2] RP 1-11466 RX PUBMED; 35094503. RA Turner TR, Hayward DR, Gymer AW, Barker DJ, Leen G, Cambridge CA, RA Macpherson HL, Georgiou X, Cooper MA, Robinson J, Mayor NP, Marsh SGE; RT "Widespread non-coding polymorphism in HLA class II genes of International RT HLA and Immunogenetics Workshop cell lines."; RL HLA 99:328-356(2022). XX CC -------------------------------------------------------------------------- CC The sequence below is the official allele sequence as approved by the CC WHO Nomenclature Committee for Factors of the HLA System. CC Any cross references may differ from the sequence shown below. CC -------------------------------------------------------------------------- XX DR EMBL; AY831401; AY831401.1. DR EMBL; LR813399; LR813399.1. DR EMBL; LR813450; LR813450.1. XX FH Key Location/Qualifiers FH FT source 1..11466 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT /ethnic="Asian" FT /cell_line="CHI 007" FT /cell_line="T7526" FT CDS join(367..466,5006..5269,9221..9502,10050..10160, FT 10490..10509) FT /codon_start=1 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*107:01" FT /product="MHC Class II HLA-DPB1*107:01 sequence" FT /translation="MMVLQVSAAPRTVALMALLMVLLTSVVQGRATPENYVYQLRQECY FT AFNGTQRFLERYIYNREEYARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEERAVPDR FT ICRHNYELDEAVTLQRRVQPKVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQ FT EETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYICQVEHTSLDSPVTVEWKAQSDSA FT RSKTLTGAGGFVLGLIICGVGIFMHRRSKKVQRGSA" FT UTR 1..366 FT exon 367..466 FT /number="1" FT intron 467..5005 FT /number="1" FT exon 5006..5269 FT /number="2" FT intron 5270..9220 FT /number="2" FT exon 9221..9502 FT /number="3" FT intron 9503..10049 FT /number="3" FT exon 10050..10160 FT /number="4" FT intron 10161..10489 FT /number="4" FT exon 10490..10509 FT /number="5" FT UTR 10510..11466 SQ Sequence 11466 BP; 3113 A; 2552 C; 2958 G; 2843 T; 0 other; taatccctgt agatgggcca gcagaatatt tgagatcacc ttcagagcaa agaaaacgca 60 taatctcccc aaacatcatg acttatctga ctggttaaaa tgagtatcac tgtccttcct 120 ccgtcatctt aagtgcatca caggctttat attttcagac ctttcatact aactttctgc 180 ccagtgagca atgactcata caaagctcag tgtctattgg ttcttttctc agactctgtc 240 caatcccagg gtcacagaag actacttggg ttcatggtct ctaatatttc aaacaggagc 300 tccctttagc gagtccttct tttcctgact gcagctcttt tcattttgcc acccttttcc 360 agctccatga tggttctgca ggtttctgca gccccccgga cagtggctct gatggcgtta 420 ctgatggtgc tgctcacatc tgtggtccag ggcagggcca ctccaggtaa gagtcgagct 480 gccattcctg gagggtctgg ctcagggaac aattcctagg ggacgttatc tttaagggat 540 caaattctga gacaggctgc gggggctcct gccctaagcc agtgtcctcc cttcccagct 600 agagaaagag gtttatcccc tataggatac cttgctaccc tacaggccta ttctctctcc 660 aaggacatgg gtacagtaaa cagagagagg tgcccagtgg tcagtatgct tgtctttggg 720 gaaaatggga ccaagaggtc caggataacc ttggacagac aaggtttgca gagagagaag 780 ttggcaagtg caggctcctg ggcgtgttca catctgcatc cagcctggag gggactcagg 840 cagagagccc taagctggag tgtccaggct ctgaggatca ctgaggattc agtgctcacg 900 aagaatgcct ctcattcccc agggtggagc aggagcccac atcccttgga caattaagga 960 gagaagggag ggagggggat aggttttagc ccctgaaggc attctcatta aaggtacttc 1020 tcccagcctc cccagaactt ggttagagta ctagagtggg ttgcaacttg taggaagaat 1080 gagatgaggt tgtgtcggtg catgaccggg attgagtgta ggttatcaga cagccaagga 1140 agcagtaacc aagtgaaaaa tctcttcttc ctgctgcctc cctgtggctg gtgtaatatt 1200 atggcatcta tgatccattg tttttctctc aggatactct caggatattt ctttttatat 1260 atatatatat atactttaag ttctagggta catgtgcaca atgtgtaggt ttgttacata 1320 tgtatacatg tgccatgttg gtgtgctgca cccattaact cgtcatttac attaggtata 1380 tttcctaatg ctatccctcc cccctccccc caccccacaa caggccctgg tgtgtgatgt 1440 tccccttcct gtgtccatgt gttctcattg ttcagttccc acctatgagt gagaacatgt 1500 ggtctttggt tttttgtcct tgcaatagtt tgctgtgaat gatggtttcc agcttcctcc 1560 atgtccctac aaaggacatg aactcatcct tttttatggc tgcacagtat tccatggtgt 1620 atatgtgcac attttcttaa tccagtctat cactgataga catttgggtt ggttccaagt 1680 ctttgctatt gtgaatagtg ccgcaataaa catatgtgtg catgtgtctt tatagcagca 1740 tgatttataa tcctttgggt atatacccag taatgggatg gctgggtcaa atggtatttc 1800 tagttctaga tccttgagga atcgccacaa tgtcttgaga taccatctca caccagttaa 1860 aatggcgatc attaaaaagt caggaaacaa caggtgctgg agaggatgtg gagaaatagg 1920 aacactttta cactgttggt gggactgtaa actagttcaa ccattgtact ctcaggacat 1980 ttctagtcca aatttacacc aacactctga gaggaaggac tgcaaagtag gtaccttagt 2040 tttccactga cttccacctt tcctgcttac acccttcctc ctagacccct ccacacccct 2100 cctaggacac acctagaagg tactgacatc atgtcacctc ctcatctttc agggtagcaa 2160 ggttggaatc tcctgaatac agcccctcaa gccctaaaac ctcttatcta ttacctcggg 2220 ttcattgtcc aggaagggga ggagaacttg aacttgtagt cacagaaggg tgctgagaac 2280 taaccagcag gacggctcag ccctgggaac tgcagagggg tgaggctggg gagagaggag 2340 gctggagcag cactggtgac actgaacagt gtcaggagga agtgacggat gcagcgcccc 2400 catcccatag gcagagctgt catgtgggat gagggacagt gttgggagcc accaaggaaa 2460 cccagaggtg ggggagcaga gagcagaagg gggcatgtga tgctgggcag tgaaagggag 2520 gacaggcaaa ggctgggttg aggtttgtag ggggaatgag atgaggcagt ggagccatgt 2580 gacagggact gagggtagat tactggagct ccctgcgtag aatgaatgtt caatcaaaac 2640 ctgctggagg gagagctgga gccatagggg agtgggtaaa gtgggcaggg ttgattccac 2700 aattccctgc atgctccccc aactccacac acatccccaa cctcaaacag ggcacaagac 2760 caaagggctg aggagccagg ctatagctta aagaggctgg gggagaaaag cttggctgag 2820 acaacccata gggagctaga ggtttttaat atatcctatt ctgaataaga gacgaattca 2880 ttcagatcag tggtttcaaa ccgtgctctg ggcaactcaa ttgctaaggg ttccacaaac 2940 aggataaagt ttcttatata caaaaaaaat gaaggtttca aattacacca taaaacccct 3000 cattgcttat gtctacttgg caggtaaaat tccatttcaa aagttaaatg tacttaaaaa 3060 attacctaag actgggtaaa ttaaaaaaat taaatgttgc aaagaaaaaa ttcaaaattc 3120 ttattcttga atgaaaaacg ttctcttact ggtgattgag gaggagaaac aaagactaac 3180 aaatgaaaat gggagaatcc acactcagag tggggcaatt gaacaggcag gggcggatgg 3240 atggcagagg aggaggaatc tggactcaag gagctggggg gccctgggcc tggaatttca 3300 gggtctgggg cccaaggcac caggagaaga ggcaggtcag gatatctgag tcaagacctg 3360 ggatcttgcc ttagcaatga cactggagac taaaggtgga ctccatggtg cccttgagcc 3420 cagccctacc ccatctccac tatcctctgc caccagctgt gcaacttctg caaggggtga 3480 ggttaataaa ctggagaagt taatttgtgg agcatgaaac agatgagcag aacaatcaca 3540 gcaccttaat ttccccagtg tgcccaagaa cagagcaggc ctgaagacac tcaaacagaa 3600 acaaacatgt gccgtgtcac tgataattct gtgtagacac acacctgcca gacactgctc 3660 atggcactcc ctaggaagaa cagcatgtgg gaaaggctgc caaaattgtt catgtaaaaa 3720 ttacatcaat gctgtcttcc tcggtgctgc ctatgcagct ggcagccatc tcttcctcca 3780 catcatggcc tccctcagac tcctcatgaa ggataagatc ctcaaaaaga ggaccaacaa 3840 gttcatgagg caccaatcag actgaaatgt caaaattaag cataactggc ggaaacccag 3900 aggtcttaac agtagggttc gtagaaggtc caagggccag atcttgatgc ccaacattgc 3960 ttatgggagc aacaacaaca acaaaaaaca catgctgccc agtggcttcc agaagtttct 4020 ggcccacagc ctcaaggagc tgaaagtgct gctgatgtgc aacaaatctt actgtgctga 4080 gatcgctcac aaaatttcct ccagaactgc aaagtcatca tggaaagagt cacccagccg 4140 gccatcagag tcaccaaccc cagtaccagg gtgcacagct aagaaaatga gtagaaagtt 4200 catgtccacg ttttgtgtgt aaataaaacc ataaaaactg ccaaaaaaaa ttacatcaat 4260 gcctctaaac ccaaaggact ctacccccac aggtccctgg ttgttgtggt gattttcatt 4320 gtgtaaaata ctttccacat cttttgacac caagtctttc tgcagccatg tttgaaaatt 4380 aactttcagg ctacagagtc tttcttatac caaagttgaa gaaagtttta agaaatatat 4440 ttctacatct cctacatgca aaacaacagg agcaagttga ggaattctca agaaactggt 4500 cgagaagaga gagcgcttag ctatggaaaa gagaaagaag gaagggaggg cttcctggag 4560 gaggtggcat ttgaaccagg actgacatca ggatggaaat gtcagtcagg gagttaagta 4620 gggggagcag ctccgccctc cacgtcccca gctcctcccg cccctgtttt ttctcccagt 4680 gaccccacgt gaaacgtctc cgcctcctcc agccaccagc agaagggact gccttcccct 4740 cagtgctcgc ccctccctag tgatcactca gtgcccctga gctcattctt ttcagtaaat 4800 tctctctctg cgtggtgaga aaacaggcct ggagaggctc tgcgacccgc ttaggaccac 4860 agaactcggt actaggaaaa ctcctatttt aaaatccagc cctgagtggg aagatttggg 4920 aagaatcgtt aatattgaga gagagaggga gaaagaggat tagatgagag tggcgcctcc 4980 gctcatgtcc gccccctccc cgcagagaat tacgtgtacc agttacggca ggaatgctac 5040 gcgtttaatg ggacacagcg cttcctggag agatacatct acaaccggga ggagtacgcg 5100 cgcttcgaca gcgacgtggg ggagttccgg gcggtgacgg agctggggcg gcctgctgcg 5160 gagtactgga acagccagaa ggacatcctg gaggaggagc gggcagtgcc ggacaggata 5220 tgcagacaca actacgagct ggacgaggcc gtgaccctgc agcgccgagg tgagtgaggg 5280 ctttgggccg gcggtcccag ggcagccccg cgggcccgtg cccagggcgc aggagcagcc 5340 gggttggcct aagggacctt agtgccgggc ggaaagggga ctttgggttg gggattcatg 5400 gggggagccc atctggagct tgtcagggga gcgagcgcgg ggacctggac tgggctgagc 5460 atggagtgag gaggacggga gcagagagac cccggggact tcatcaggcc tggcagctga 5520 ctgcatgtgg ggtgaaaaaa aggaagccac aggacagcgc acaagggtat ggtgtggaga 5580 tggaggtgga gatggcacag caggccacac agagaagaaa cctacaggga gttagctggg 5640 tttgaggtgc ttgaggggca gatgggtggt ctgatgggca ggtagacaga agggtctgca 5700 gccggggagg agactgagat acatgagacc atccagggag aggggaccca gggggaagag 5760 caaaggactg gatcctggga actggacagt tgtgatttgg ccaagacaga aaagcctgtg 5820 aaagagacca ataaaaccca agtgcagtgt gaggagaggc ccgcagagaa gagtcttgga 5880 agctgagggg aggtgacctc agcagcacag tggacagcgg tgccagtgac ttgggaaggt 5940 cagaaaacag aagatggaaa gtgggtttgg aaaccaggga gacctgggga gagcaggttg 6000 gccgcagcgg caggagctgg aatgggaggg ggtgcatgag gctgagtgtg gcgcatcctc 6060 ctcggggctg agatggattt tacttgtctt gggttcccca cggctgtcac agggcagtgt 6120 ctgagttcat tcgtcttttt ccttcaggaa gtctgggtgt aaagggatgg agagaggtga 6180 ggtgtgtgca gtaagaggat ttctcaagga tgggacagga aggccttgga gctttggctt 6240 cctcctgtga acttgtgggg tggggagcct ggtgcaccaa cctttgggac ttgagggagt 6300 agtatcagga tgtgggattg agccctggac cttttttcta gaaagaggaa aaaaatgaag 6360 ggaggaggag gaggaagctg gggagatcac acctttgatt ttcttgttcc tggaaagtga 6420 aaggaagttc acctgctatg agtgagaagg tggacacact gggtggggat gaggtgagtg 6480 acatgagctt aggaaagttg ctgaggtaat tggttgagag aggtgttcaa ataaaagtaa 6540 tgcaattggc aaaaactgtt actaagactt tgtagaggca caaatcagtg acatggcagc 6600 atcttctttc acagtaatca actgccagat tgcagggagc cctgatacca gcctaaggag 6660 tgtgagtttc tcctctaggc ccacaggtcc ccaacctcac tcctccgaag actctcctgg 6720 agatcatctg tgatgcgcag atacccagac tcactgcccc gagactcaga ttccctgggt 6780 ggggaggtct ggggatctct gcttgtaatc agctccctag aggttcccat gtagccggat 6840 aagtattgtc agaacactga agatttttga aaaatgaaaa agagaaggtt ggagatgtgt 6900 cttcagaaga ctactaaggg tgctgggtag aggagggacc agaggcaggg agatgaggta 6960 ggaaactgct attatttgtc agggaaattg caatcaagaa atgagttaga acagggaaaa 7020 cacagaggca ggggagaggt ggaaggggga ggaaaggagt agtgacaatt ccagggtgta 7080 tgctcaccca aatctagaag taattgagca aatgttttct gggcattaga gaaggcaact 7140 agaacaaaca ggaatccttg ccttggtgaa atgtatttga actgggtcag aaatgaggcc 7200 attgggtatc aagccttaac tccagcgccc cctggaggtc gctgatgtgg ctccaggctg 7260 acctgctcct gtcaaagaat attgagcaag atgcctctca tggaatgttc tgggacctta 7320 aaacagatac ccaagtattc cccctgattt catggttccc agaagctcta tggggaagaa 7380 attgtacgta attcacaact gagatttaga cataagttga atagtgtaat ggacgttgag 7440 ttaaccgagg taatgaagta gtgagacaca ggtgcccctg aaataaactc acattgaggg 7500 aagaggctga caatgtggat cagtctgtaa acaaggcaaa aatacaatag ggagtaaggg 7560 ttgtgtgtca gttcaagact gtacttttac ctggcccagc gccatgttgg ggtatttgtg 7620 ttctccagga agtagaaagg aaagaactga gtgattaggg acctagaaga ctaatttgag 7680 acattcctct tgatgaactg ttctctaggg tagtcctctg aaagagctgt tctctagtgg 7740 atctccctga atgaactgtt ctctaggagc acttgaccct tttctgtgtt tgttttttgt 7800 tttgtgtttg tgtttgtttt tgagacaggt tctcgctctg tctcccaggc tggagtgctg 7860 tggcgccatc atgactcact gcagcctcaa cctcctgggc tcaagtgatc ctcctgcctc 7920 agcctcccat gtagctagaa ctacagatac atgtaccacc atgtctggct aatttatttt 7980 tctttttaga gatgggttct cactatgttg cccaggctgg tctcgaaacc ctgggctcaa 8040 gtgatcctca cgcctcagcc tcccaaagtg ctaagattat aggcatgacc accatgcctg 8100 gccttttctg ccttccgaga aggaaaaagg tactggtggc agagatccaa aagaaaagtt 8160 gccagtggca gtgtggaaat tgacctgaga acaacagaac aagctggggc acaaatgcaa 8220 agatgcagag ggaggcaaca tctggttatc tgtgagacct tcatgggacc tgaagacaca 8280 tccttttgga aaaggatggg atttctacta ctcaagcatg taggggctca ggatattatg 8340 taaatatgaa gattttgagt ttttgtaagt gaggtaaaaa aaatacccag gttatttaca 8400 gaataagaca tgtcaagctc tcttcatttt ctttgtattt tcatgaaata aaggtattag 8460 attaacaggc caccataatg ccattgtctg tatatcttaa tttcaagata ttatttgagt 8520 aatttttgca tcctttgtat caagatagaa ctttgaaaag acaggtaatt tcacagttga 8580 ttaaatattc tttgcccaaa ttacttttgg ttaaaatttc tcctatatgt gctacagagt 8640 gcaaactctg tctccctgcc attccgctat atacttacta attattattt tattcaagat 8700 catgcatgct ctacttgaag gtctatcttt tcagtgctac ccttacccac tagcctaatc 8760 acattatatc tattttcaac atctaggaat caattacgta gtgaacatgc ctaagaaata 8820 ataatctggg cagatgcagt ggctcaggcc tgtaatccca gcactttgag aggctgagcg 8880 ggtggatcac ttgaggtcag gagttggtca agtgctccta gagaaccagc ctgaccaaca 8940 tggagaaacc ttgtctctac tgataataca aaaattagcc aggtgaggtg gcaggcacct 9000 ataatcccag ctattcggga ggctgaggaa ggagaattgc ttgaacccct gaggtggagg 9060 ttgcagtgag ccaatattgc gccactgcat tccagacttg gcaacagagc gacactccac 9120 ctcaacaaaa agaaagaaag agcgagatta cgtctcaaaa aaggaaggaa ggaaggacaa 9180 tctcaaatgc tatttcatta ttttccttcc ccactcgtag tccagcctaa ggtgaacgtt 9240 tccccctcca agaaggggcc cctgcagcac cacaacctgc ttgtctgcca cgtgacagat 9300 ttctacccag gcagcattca agtccgatgg ttcctgaatg gacaggagga aacagctggg 9360 gtcgtgtcca ccaacctgat ccgtaatgga gactggacct tccagatcct ggtgatgctg 9420 gaaatgaccc cccagcaggg agacgtctac atctgccaag tggagcacac cagcctggac 9480 agtcctgtca ccgtggagtg gagtgagtct ctgatgaccg tctagacccc acctctgaag 9540 agcaggggac tctctggctc tggggtccac tcatcttatc ttctgcatct ataccctggg 9600 gccatgtcca aaccccatct ttcttctata ccagctcctg agcatagttt gaagccaggg 9660 caatggagac ttcctgacct tggcttaggg gttcctgaag attcatagtt ctcccccttg 9720 tcagagaatc tagggacact ggctgatctc gaaaccctca cacacaggaa ctgacctcac 9780 acataggaac agttctcttc tttcagcatt ttagcctctt ctcaggcatt ttgagaggca 9840 acttctagaa tcagcatttg ccaccttgtt gaggtcacac ccctgttccg gacatgaggg 9900 tggctctttc tgaatttcct cttagcaagc tttttcccct gcactgtctt catcccgata 9960 ttctgcatca cgctccagaa tctcagacag gacatgagta gggatgcagc tggtggaggt 10020 gacactaaac ctgggtctgt ccttcccaga ggcacagtct gattctgccc ggagtaagac 10080 attgacggga gctgggggct tcgtgctggg gctcatcatc tgtggagtgg gcatcttcat 10140 gcacaggagg agcaagaaag gtgagaaagc ctgcaaggtg agcgggacct accttcccct 10200 ggcatattca cacttactcc atgatgaggg ttcagacaga aaagaaatgt cagaaagctc 10260 tagagaccac tgaaatcaga tagtcgggga acaaacatga cctatggcga gagggggatc 10320 ccaggctggg atcttaatgc agccagatgc atgaggtccc aggtgctcag actcctgcgg 10380 ggcatccatt gagtggtggt caatggaatt tggtgggatg gaaatgtttc tctaactatc 10440 tgaggtggtt tcaatggctg aatacataac ctttcctctt tcatttcagt tcaacgagga 10500 tctgcataac aggtaatatt cctgctttga tttccttggg gggtgggtta caggaggata 10560 tgactccttt ctgtgcattg taatactgag gctcctccag gaagggaatc tcaggcatga 10620 acccctcttt caacctcagc tctcgggtga gtagggaaaa agcattgcac ggctccattg 10680 ctgaaggaag cagagatcag ttctgttctt tatcagccta agatgcagcc tctcaccata 10740 atttttctct cctggactta aaggaaggag gccagcaacc tgggataact tgtcctttac 10800 ccccacaggg ttcctgacct caccgaaaag actaatgtgc cttagaacaa gcatttgctg 10860 tgttttgtta gcacctggtt ccaggacaga ccctcagctt cccaagagga tactgctgcc 10920 aagaacttgc tctgaagtca gtttctatcg ttctgctctt tgattcaaag cactgtttct 10980 ctcactgggc ctccaaccat gttcccttct tcttagcacc acaaataatc aaaacccaac 11040 ataagtgttt gttttccttt aaaaatatgc atcaaatcgt ctctcattac tttgagggtt 11100 ttagtaaaca gtaggagtta ataaagaagt tcattttggt ttacacatag gaaagaagag 11160 aagcatgaaa gtggagatat gttaactatt gtataatgtg gcctgttata catgacactc 11220 ttctgaattg actgtatttc agtgagctgc ccccaaatca agtttagtgc cctcatccat 11280 ttatgtctca gaccgctatt cttaactatt caatggtgag cagactgcaa atctgcctga 11340 taggacccgt attcccacag cactaattca acatatatct tactgagagc atgttttatc 11400 attaccatta agaagttaaa tgaacatcag aatttaaaat cataaatata atctaataca 11460 ctttaa 11466 //