Dbfetch
ID HLA02048; SV 1; standard; DNA; HUM; 11528 BP. XX AC HLA02048; XX SV HLA02048.1 XX DT 13-DEC-2004 (Rel. 2.8.0, Created, Version 1) DT 16-JAN-2024 (Rel. 3.55.0, Last Updated, Version 1) XX DE HLA-DPB1*106:01, Human MHC Class II sequence XX KW Human MHC; HLA; Class II; HLA-DPB1; Allele; HLA-DPB1*106:01; XX OS Homo Sapiens (human) OC Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates; OC Catarrhini; Hominidae; Homo. XX CC -------------------------------------------------------------------------- CC IPD-IMGT/HLA Release Version 3.55.0 CC -------------------------------------------------------------------------- CC Copyrighted by the IPD-IMGT/HLA Database, Distributed under the Creative CC Commons Attribution-NoDerivs License, see; CC http://www.ebi.ac.uk/ipd/imgt/hla/licence/ for further details. CC -------------------------------------------------------------------------- XX RN [1] RP 1-11528 RX PUBMED; 16189666. RA Reinders J, Rozemuller EH, van Gent R, Arts-Hilkes YH, van den Tweel JG, RA Tilanus MG; RT "Extended HLA-DPB1 polymorphism: an RNA approach for HLA-DPB1 typing."; RL Immunogenetics 57:790-794(2005). XX RN [2] RP 1-11528 RX PUBMED; 29879452. RA Klasberg S, Lang K, Gunther M, Schober G, Massalski C, Schmidt AH, Lange V, RA Schofl G; RT "Patterns of non-ARD variation in more than 300 full-length HLA-DPB1 RT alleles."; RL Human Immunology 80:44-52(2019). XX CC -------------------------------------------------------------------------- CC The sequence below is the official allele sequence as approved by the CC WHO Nomenclature Committee for Factors of the HLA System. CC Any cross references may differ from the sequence shown below. CC -------------------------------------------------------------------------- XX DR EMBL; AY804132; AY804132.1. DR EMBL; LT707799; LT707799.1. XX FH Key Location/Qualifiers FH FT source 1..11528 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT /ethnic="African, Undefined" FT /cell_line="DAUDI" FT /cell_line="DKMS-LSL-DPB1-1454" FT CDS join(367..466,5001..5264,9277..9558,10106..10216, FT 10546..10565) FT /codon_start=1 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*106:01" FT /product="MHC Class II HLA-DPB1*106:01 sequence" FT /translation="MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECY FT AFNGTQRFLERYIYNREEFVRFDSDVGEFRAVTELGRPEAEYWNSQKDILEEERAVPDR FT ICRHNYELDEAVTLQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQ FT EETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSA FT RSKTLTGAGGFVLGLIICGVGIFMHRRSKKVQRGSA" FT UTR 1..366 FT exon 367..466 FT /number="1" FT intron 467..5000 FT /number="1" FT exon 5001..5264 FT /number="2" FT intron 5265..9276 FT /number="2" FT exon 9277..9558 FT /number="3" FT intron 9559..10105 FT /number="3" FT exon 10106..10216 FT /number="4" FT intron 10217..10545 FT /number="4" FT exon 10546..10565 FT /number="5" FT UTR 10566..11528 SQ Sequence 11528 BP; 3132 A; 2545 C; 3000 G; 2851 T; 0 other; taatccctgt agatgggcca gcagaatatt tgagatcacc ttcagagcaa agaaaacgca 60 taatctcccc aaatatcatg acttatctga ctggttaaaa tgagtatcac tgtctttcct 120 ccgtcatctt aagtgcatca caggctttat attttcagac ctttcatact aactttctgc 180 ctagtgagca atgactcata caaagctcag tgtccattgg ttcttttctc agactctgtc 240 caatcccagg gtcacagaag actacttggg ttcatggtct ctaatatttc aaacaggagc 300 tccctttagc gagtccttct tttcctgact gcagctcttt tcattttgcc atccttttcc 360 agctccatga tggttctgca ggtttctgcg gccccccgga cagtggctct gacggcgtta 420 ctgatggtgc tgctcacatc tgtggtccag ggcagggcca ctccaggtaa gagccgagct 480 gccattcttg gagggtctgg ctcagggaac aattcctagg ggacgttatc tttaagggat 540 caaattctga gacaggctgc gggggctcct gccctaaggc agtgtcctct cttcccagct 600 agagaaagag gttcatcccc tataggatag cttgctaccc tactggccta ttctctctcc 660 aaggacatgg gtacagtaaa cagagagagg tgcccagtgg tcagtatgct tgtctttggg 720 gaaaatggga ccaagaggtc caggataacc ttggacagac aaggtttgca gagagagaag 780 ttggcaagtg caggctcctg ggcgtgttca catctgcatc cagcctggag gggactcagg 840 cagagagccc taagctggag tgtccaggct ctgaggatca ctgaggattc agtgctcacg 900 aagaatgcct cttattcccc agggtggagc aggagcccac accccttgga caattaagga 960 gagaagggag ggagggggat aggttttagc ccctgaaggc attctcatta aaggtacttc 1020 tcccagcctc cccagaactt ggttagggta ctagagtggg ttgcgacttg taggaagaat 1080 gagatgaggt tgtgtgggtg catgacaggg attgagtgta ggttatcaga cagccaagga 1140 agcagtaacc aagtgaaaaa tctcttcttc ctgctgcctc cctgtggctg gtgtaatatt 1200 atggcatcta tgatccattg tttttctctc aggatactct caggatattt ctttttatat 1260 atatatatac tttaagttct agggtacatg tgcacaacgt gcaggtttgt tacatatgta 1320 tacatgtgcc atgttggtgt gctgcaccca ttaactcgtc atttacatta ggtatatttc 1380 ctaatgctat ccctcccccc tccccccacc ccacaacagg ccccggtgta tgatgttccc 1440 cttcctgtgt ccatgtgttc tcattgttca gttcccacct atgagtgaga acatgtggtc 1500 tttggttttt tgtccttgca atagtttgct gtgaatgatg gtttccagct tcctccatgt 1560 ccctacaaag gacatgaact catccttttt tatggctgca cagtattcca tggtgtatat 1620 gtgtgcattt tcttaatcca gtctatcact gatggacagt tgggttggtt ccaagtcttt 1680 gctattgtga atagtgccgc tataaacata tgtgtgcatg tgtctttata gcagcatgat 1740 ttataatcct ttgggtatat acccagtaat gggatggctg ggtcaaatgg tatttctagt 1800 tctagatcct tgaggaattg ccacaatgtc ttgagatacc atctcacacc agttaaaatg 1860 gcgatcatta aaaagtcagg aaacaacagg tgctggagag gatgtggaga aataggaaca 1920 cttttactct gttggtggga ctgtaaacta gttcaaccat tgtactctca ggacatttct 1980 agtccaaatt tacaccaaca ctctgagagg aaggactgca aagtaggtac cttagttttc 2040 cactgacttc cacctttcct gcttacaccc ttcctcctag acccctccac acccctccta 2100 ggacacacct agaaggtact gacatcatgt cacctcctca tctttcaggg tagcaaggtt 2160 ggaatctcct gaatacagcc cctcaagccc taaaacctct tatctattac ctcgggttca 2220 tgtccaggaa ggggaggaga acttgaactt atagtcacag aagggtgctg agaactaacc 2280 agcaggacgg ctcagccctg ggaactgcag aggggtgagg ctggggagag aggaggctgg 2340 agcagcactg gtgacactga acagtgtcag gaggaggtga cggatgcagc gcccccatcc 2400 cataggcaga gctgtcatgt gggatgaggg acagtgttgg gagccaccaa ggaaacccag 2460 aggtggggga gcagagagca gaagggggca tgtgatgctg gacagtgaaa gggaggacgg 2520 gcaaaggctg ggttgaggtt tgtaggggga atgagatgag gcagtggagc catgtgacag 2580 ggactgaggg tagattactg gagctccctg cgtagaatga atgttcaatc aaaacctgct 2640 ggagggagag ctggagccat aggggagtgg gtaaagtggg cagggctgat tccacaattc 2700 cctgcatgct cccccaactc cacacacatc cccaacctca aacagggcac aagaccaaag 2760 ggctgaggag ccaggctata gcttaaagag gctgggggag aaaagcttgg ctgagacaac 2820 ccatagggag ctagaggttt ttaatatatc ctattctgaa taagagacga attcattcag 2880 atcagtggtt tcaaaccgtg ctctgggcaa ctcaattgct aagggttcca caaacaggat 2940 aaagtttctt atatacaaaa aaaatgaagg tttcaaatta caccataaag cccctcattg 3000 cttatgtcta cttggcaggt aaaattccat ttcaaaagtt aaatgtactt aaaaaattac 3060 ctaagactgg gtaaattaaa aaaattaaac gttgcaaaga aaaaattcaa aattcttatt 3120 cttgaatgaa aaacgttctc ttactggtga ttgaggagga gaaacaaaga ctaacaaatg 3180 aaaatgggag aatccacact cagagtgggg caattgaaca ggcaggggcg gatggatggc 3240 agaggaggag gaatctggac tcaaggagct ggggggctct gggcctggaa ttttagggtc 3300 tggggcccaa ggcaccagga gaagaggcag gtcaggatat ctgagtcaag acctgggatc 3360 ttgccttagc aatgacactg gagactaaag gtggactcca tggtgccctt gagcccagcc 3420 ctaccccatc tccactatcc tctgccacca gctgtgcaac ttctgctagg ggtgaggtta 3480 ataaactgga gaagttaatt tgtggagcat gaaacagatg agcagaacaa tcacagcacc 3540 ttaatttccc cagtgtgccc aagaacagag caggcctgaa gatactcaaa cagaaacaaa 3600 catgtgccgt gtcactgata attctgtgta gacacacacc tgccagacac tgctcatggc 3660 actccctagg aagaacagca tgtgggaaag gctgccaaaa ttgttcatgt aaaaattaca 3720 tcaatgctgt cttcctcggt gctgcctatg cagctggcag ccatctcttc ctccacatca 3780 tggcctccct cagactcctc atgaaggata agatcctcaa aaagaggacc aacaagttca 3840 tgaggcacca atcagactga aatgtcaaaa ttaagcataa ctggcggaaa cccagaggtc 3900 ttaacagtag ggttcgtaga aggtccaagg gccagatctt gatgcccaac attgcttatg 3960 ggagcaacaa caacaacaaa aaacacatgc tgcccagtgg cttccagaag tttctggtcc 4020 acagcctcaa ggagctgaaa gtgctgctga tgtgcaacaa atcttactgt gctgagatcg 4080 ctcacaaaat ttcctccaga actgcaaagt catcatggaa agagtcaccc agccggccat 4140 cagagtcacc aaccccagta ccagggtgca cagctaagaa aatgagtaga aagttcacgt 4200 ccacgttttg tgtgtaaata aaaccataaa aactgccaaa aaaaattaca tcaatgcctc 4260 taaacccaaa ggactctacc cccacaggtc cctggttgtt gtggtgattt tcattgtgta 4320 aaatactttc cacatctttt gacaccaagt ctttctgcag ccatgtttga aaattaactt 4380 tcaggctaca gagtctttct tataccaaag ttgaagaaag ttttaagaaa tatatttcta 4440 catctcctaa atgcaaaaca acaggagcaa gttgaggaat tctcaagaaa ctggtcgaga 4500 agagagagcg cttagctatg gaaaagagaa agaaggaagg gagggcttcc tggaggaggt 4560 ggcatttgaa ccaggactga catcaggatg gaaatgtcag tcagggagtt aagtaggggg 4620 agcagctccg ccctccacgt ccccagctcc tcccgcccct gttttttctc ccagtgaccc 4680 cacgtgaaac gtctccgcct cctccagcca ccagcagaag ggactgcctt cccttcagtg 4740 ctcgcccctc cctagtgatc actcagtgcc cctgagctca ttcttttcag taaattctct 4800 ctctgcgtgg tgagaaaaca ggcctggaga ggctctgcga cccgcttagg accacagaac 4860 tcggtactag gaaaactcct attttaaaat ccagccctgg gtgggaagat ttgggaagaa 4920 tcgttaatat tgagagagag agggagaaag aggattagat gagagtggcg cctccgctca 4980 tgtccgcccc ctccccgcag agaattacct tttccaggga cggcaggaat gctacgcgtt 5040 taatgggaca cagcgcttcc tggagagata catctacaac cgggaggagt tcgtgcgctt 5100 cgacagcgac gtgggggagt tccgggcggt gacggagctg gggcggcctg aggcggagta 5160 ctggaacagc cagaaggaca tcctggagga ggagcgggca gtgccggaca ggatatgcag 5220 acacaactac gagctggacg aggccgtgac cctgcagcgc cgaggtgagt gagggctttg 5280 ggccggcggt cccagggcag ccccgcgggc ccgtgcccag ggcgcaggag cagccgggtt 5340 ggcctaaggg accttagtgc cgggcggaaa ggggactttg ggttggggat tcatgggggg 5400 agcccatctg gagcttgtca ggggagcgag cgcggggacc tggactgggc tgagcatgga 5460 gtgaggagga cgggagcaga gagacccccg ggacttcatc aggcctggca gctgactgca 5520 tgtggggtga gaaaaggaag ccacaggaca gcgcacaagg gtgtggtgtg gagatggagg 5580 tggagatggc acagcaggcc acacagagaa gaaacctaca gggaggtagc tgggtttgag 5640 gtgcttgagg ggcagatggg tggtctgatg ggcaggtaga cagaagggtc tgcagccgag 5700 gaggagactg agatacatga gaccatccag ggagagggga cccaggggga agagcaaagg 5760 accggatcct gggaactgga cagttgtgat ttggccaaga cagaaaagcc tgtgaaagag 5820 accaaaaaaa cccaagtgcg gtgtgaggag aggcccgcag agaagagtct tggaagctga 5880 ggggaggtga cctcagcagc acagtggaca gcggtgccag tgacttggga aggtcagaaa 5940 acagaagatg gaaagtgggt ttggaaacca gggagacctg gggagagcag gttggccgca 6000 gcggcaggag ctggaatggg agggggtgca tgaggctgag tgtggcgcat cctcctcggg 6060 gctgagatgg attttacttg tcttgggttc cccacggctg gcacagggca gtgtctgagc 6120 tcatttgtct tttccttcag gaagtcgggg tgtaaaggga cggagagagg tgaggtgtgt 6180 gcagtaagag gatttctcaa ggatgggaca ggagggcctt ggagctttgg cttcctcctg 6240 tgaatttgtg gggtggggag cctggtgcac caacctgagg gacctgaggg agtagtatca 6300 ggatgtggga ttgacccctg gacctttttt ctagaaagag gaaaaaatga agggaggagg 6360 aggaggaagc tggggagatc acacctttga ttttcttgtt cctggaaagt gaaaggaagt 6420 tcacctgcta ggagtgagaa ggtggacaca ttgggtgggg atgaggtgag tgacatgagc 6480 ttaggaaagt tgctgaggta attggttgag agaggtgttc aaataaaaat aacgcaattg 6540 gcaaaaactg ttactaagac tttgtagagg caccaatcag tgacatggca gcattttctt 6600 tcacagtaat caactgccag attgcagaca gccctgatgc cagcctaagg agtgtgggtt 6660 tctcctccag gcccgcaggt ccccaacctc actcctctga agactcttct ggagatcctc 6720 tgtgatgcac agatctccag actcagtgcc cccagactca gattccctgg gtggggaggt 6780 ctggggatct ctgcttgtaa tcagctccct agaggttccc atgtagccag ataagtattg 6840 tcagaacact gaagattttt gaaaaatgaa aaagagaagg ttggagatgt gtcttcagaa 6900 gactactaag ggtgctggct agaggaggga ccagaggcag ggagatgagg taggaaactg 6960 ctattatttg tcagggaaat tgcaatcaag gcatgagtta gaacggggaa aacacagagg 7020 caagggagag gtggaagggg gaggaaagaa gtagtgacaa ttccagggtg gatgtccacc 7080 caaatctaga agtaattgag caaatgtttt ctgggcatta gagaaggcaa ctagaacaaa 7140 caggaatcct tgccttggtg aaatgtattt gaactgggtc agaaatgagg ccattgggta 7200 tcaggcctta actccagcgc accctggagg tcgctgatgt ggctccaggc tgacctgctc 7260 ctgtcaaaga atattgagca agatgcctct cgtggaatgt tctgggacct taaaacagat 7320 acccaagtat tccccctgat ttcatggttc ccagaagctc tatggggaag aaattgtagg 7380 taattcacaa ctgagattta gacataagtt gaatagtgta atggacattg agttaaccga 7440 ggtaatgaag tagtgagaca caggtgcccc tgaaataaac tcacattgag ggaagaggct 7500 gacaatgtgg atcagtctga aaacaaggca aaaatacaat agggagtaag ggttgtgtgt 7560 cagttcaaga ctgtactttt acctggccca gcgccatgtt agggtatttg tgttctccag 7620 gaagtagaaa tgaaagaact gagtgattag ggacctagaa gactaatttg agacattcct 7680 cttgatgagc tgttctctag ggtagtcctc tgaaagagct gttctctagt ggatctccct 7740 gaatgaactg ttctctagga gcacttgacc cttttctgtg tttgtttttt gttttgtgtt 7800 tgtgtttgtt tttgagacag gttctcactc tgtctcccag gctggagtgc tgtggcacca 7860 tcatggctca ctgcagcctc aacctcctgg gctcaagtga tcctcctgcc tcagcctccc 7920 atgtagctag aactacagat acacgtacca ccatgtctgg ctaatttatt tttcttttta 7980 gagatgggtt ctcactatgt tgcccaggcc ggtctcaaaa ccctgggctc aagtgatcct 8040 catgcctcaa cctcccaaag tgctaagatt ataggcatga ccaccatgcc tggccttttc 8100 tgctttctga ggaggaaaaa ggtactggtg gcagagatcc aaaagaaaag ttgccagtgg 8160 cagtgtggaa attcacctga gaacaacagg acaagctggg gcacaaatgc aaagatgcag 8220 agggaggcaa cacctggtca tctgtgagac cttcatggga cctgaagacg cagcacagag 8280 gaggaacttg aaaaaggacg ggatttctac tactcaagca tgtaggagct caggatattc 8340 tgtaaatatg aagattttga gtttttgtag gtgaggtaaa aaaatacata ggttttttac 8400 agaataagac atgtaaagct ctcttcattt tctttgtatt ttcatgaagt tattagattc 8460 acaggccacc ataatgccat tgtctgtata tcttaatttc aagatattat ttgagtaaat 8520 tttgcttcct ttgtatcaag atagaacttt gaaaaggtag gtaatttcac agttgatcaa 8580 atattctttg cccaaattac ttttggttaa aatttctcct aaatgtgcta cagagtgcaa 8640 actctgtctc cctgccattc cgctatatac ttactaacta ttattttatt caagatcatg 8700 catgctctac ttgaaggtct atttctatct tttcaatgct acccttaccc actagcctaa 8760 tcacattatt cctattttca acatctagga atcaattaca tagtgaacat gcctaagaaa 8820 taataatctg ggcagatgca gtggctcagg cccgtaatcc cagccctttg agaggccgag 8880 cgggtggatc acttgaggtc aggcgttggt caagtgctcc tagagaacca ggctgaccaa 8940 catggagaaa ccttgtctct actaataata caaaaattag ccaggtgaag tggcaggcac 9000 ctataatccc agctattcgg gaggctgagg aaggagaatt ggttgaagcc cggaggtgga 9060 ggttgcagtg agccaatatt gcgccactgc attccagact tggcaacaga gtgacactcc 9120 atctcaacaa aaagaaagaa tgaaagaaag aaagagcgag attatgtctc aaaaaaaagg 9180 aaggaaggaa ggaaggaagg aaggaaggaa ggaaggaagg aaggaaagaa ggacaatctc 9240 aaattctatt tcattatttt tcttccacgc tcctagtcca gcctagggtg aatgtttccc 9300 cctccaagaa ggggcccttg cagcaccaca acctgcttgt ctgccacgtg acggatttct 9360 acccaggcag cattcaagtc cgatggttcc tgaatggaca ggaggaaaca gctggggtcg 9420 tgtccaccaa cctgatccgt aatggagact ggaccttcca gatcctggtg atgctggaaa 9480 tgacccccca gcagggagat gtctacacct gccaagtgga gcacaccagc ctggatagtc 9540 ctgtcaccgt ggagtggagt gagtctctga tgaccctcta gaccccacct ctgaagagca 9600 ggggactctc tggctctggg gtccactcac cttatcttct gcatctatac cctggggcca 9660 tgtccaaacc ccatctttct tctataccag ctcctgagca tagtttgaag ccagggaaat 9720 ggagacttcc tgaccttggc ttaggggttc ctgaagattc atagttctcc cccttgtcag 9780 agaatctagg gacactgact ggtctcgaaa ccctcacact taggaactga cctcacacat 9840 aggaacagtt ctcttccttc agcattttag cctcttctca ggcattttga gaggcaactt 9900 ccagaatcag catttgccac cttgttgagg tcacacccct gttccagata tgagggtggc 9960 tctttctgaa tttcctctta gcaagctttt tccgctgcac tgtcctcatc ccgatatgct 10020 gcatcaggct ccagaatctc agacaggaca tgagtaggga tgcagctggt ggaggtgaca 10080 ctaaacctgg gtctgtcctt cccagaggca cagtctgatt ctgcccggag taagacattg 10140 acgggagctg ggggcttcgt gctggggctc atcatctgtg gagtgggcat cttcatgcac 10200 aggaggagca agaaaggtga gaaagcctgc agggtgagcg ggacttacct tcccctggca 10260 tattcacact tattccacga tgaggggttt gacagaaaag aaatgtcaga aagctctaga 10320 ggccactgat atcagataat cggggaacaa acatgaccta tagcgagaga gggatcccag 10380 gctgggatct taatgcagcc agatgcatga ggtcccaagt actcaggctc ctgcggagcg 10440 tccattgagt gatgggcaat ggaatttggt gggatggaaa tgtttctcta attatctgag 10500 gtggtttcaa tggctgatta tataaccttt cctctttcat ttcagttcaa cgaggatctg 10560 cataaacagg taatattcct gctttgattt ccttgtgggg tgggttgcag gaggatatga 10620 gtcctttctg tgcattgtaa cactgaggct cctccaggaa gggaatctca ggcatgaacc 10680 cctctttcaa tgtcagcctt caggcaagtg gggaaagagc attgcttggc tccattgctg 10740 aaggaagcag agatcaactc tgttatttat cagcctgaga cgcatcctct caccataatt 10800 tttctctcct ggacttacag gaaggaggct ggcaacctgg gataacttgt cctttacccc 10860 cacagggttc ctgagctcac tgaaaagact attgtgcctt agaaaaagca tttgctgtgt 10920 ttcgttagca tctggctcca ggacagacct tcaacttcca aattggatac tgctgccaag 10980 aagttgctct gaagtcagtt tctatcattc tgctctttga ttcaaagcac tgtttctctc 11040 actgggcctc caaccatgtt cccttcttct tagcaccaca aataatcaaa acccaacatg 11100 actgtttgtt ttcctttaaa aatatgcacc aaatcatctc tcatcacttt tctctgaggg 11160 ttttagtaga cagtaggagt taataaagaa gttcattttg gtttaaacat aggaaagaag 11220 agaaccatga aaatggggat atgttaacta ttgtataatg gggcctgtta cacatgacac 11280 tcttctgaat tgactgtatt tcagtgagct gcccccaaat caagtttagt gccctcatcc 11340 atttatgtct cagaccacta ttcttaacta ttcaatggtg agcagactgc aaatctgcct 11400 gataggaccc atattcccac agcactaatt caacatatac cttactgaga gcatgtttta 11460 tcattaccat taagaagtta aatgaacatc agaatttaaa atcataaata taatctaata 11520 cactttaa 11528 //