Dbfetch
ID HLA01925; SV 2; standard; DNA; HUM; 4304 BP. XX AC HLA01925; XX SV HLA01925.2 XX DT 24-MAY-2004 (Rel. 2.6.0, Created, Version 1) DT 16-JAN-2024 (Rel. 3.55.0, Last Updated, Version 2) XX DE HLA-C*03:18:01, Human MHC Class I sequence XX KW Human MHC; HLA; Class I; HLA-C; Allele; HLA-C*03:18:01; XX OS Homo Sapiens (human) OC Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates; OC Catarrhini; Hominidae; Homo. XX CC -------------------------------------------------------------------------- CC IPD-IMGT/HLA Release Version 3.55.0 CC -------------------------------------------------------------------------- CC Copyrighted by the IPD-IMGT/HLA Database, Distributed under the Creative CC Commons Attribution-NoDerivs License, see; CC http://www.ebi.ac.uk/ipd/imgt/hla/licence/ for further details. CC -------------------------------------------------------------------------- XX RN [1] RP 1-4304 RX PUBMED; 18380775. RA Lazaro AM, Xiao Y, Cao K, Masaberg C, Nichol L, Ng J, Hurley CK, Posch PE; RT "Twenty-three novel alleles increase the diversity at the HLA-C locus."; RL Tissue Antigens 71:560-563(2008). XX RN [2] RP 1-4304 RX PUBMED; 30117314. RA Lazaro A, Hou L, Tu B, Masaberg C, Enriquez E, Gerfen J, Kariyawasam K, RA Persaud M, Qin X, Simbulan D, Xiao Y, Xun L, Yang R, Ng J, Hurley CK; RT "Full gene HLA class I sequences of 79 novel and 519 mostly uncommon RT alleles from a large United States registry population."; RL HLA 92:304-309(2018). XX CC -------------------------------------------------------------------------- CC The sequence below is the official allele sequence as approved by the CC WHO Nomenclature Committee for Factors of the HLA System. CC Any cross references may differ from the sequence shown below. CC -------------------------------------------------------------------------- XX DR EMBL; AH013843; AH013843.2. DR EMBL; AY607027; AY607027.1. DR EMBL; AY607028; AY607028.1. DR EMBL; LT964788; LT964788.1. DR EMBL; LT964789; LT964789.1. DR EMBL; MG911197; MG911197.1. DR EMBL; MG944948; MG944948.1. XX FH Key Location/Qualifiers FH FT source 1..4304 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT /ethnic="Undefined" FT /cell_line="DKMS-LSL-C-1787" FT /cell_line="DKMS-LSL-C-1788" FT /cell_line="NT00511" FT /cell_line="NT02023" FT /cell_line="NT02065" FT CDS join(496..568,699..968,1214..1489,2077..2352,2474..2593, FT 3033..3065,3173..3220,3385..3389) FT /codon_start=1 FT /gene="HLA-C" FT /allele="HLA-C*03:18:01" FT /product="MHC Class I HLA-C*03:18:01 sequence" FT /translation="MRVMAPRTLILLLSGALALTETWACSHSMRYFYTAVSRPGRGEPR FT FIAVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQTDRVSLRN FT LRGYYNQSEARSHIIQRMYGCDVGPDGRLLRGYDQYAYDGKDYIALNEDLRSWTAADTA FT AQITQRKWEAAREAEQLRAYLEGLCVEWLRRYLKNGKETLQRAEHPKTHVTHHPVSDHE FT ATLRCWALGFYPAEITLTWQWDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRY FT TCHVQHEGLPEPLTLRWEPSSQPTIPIVGIVAGLAVLAVLAVLGAVVAVVMCRRKSSGG FT KGGSCSQAASSNSAQGSDESLIACKA" FT UTR 1..495 FT exon 496..568 FT /number="1" FT intron 569..698 FT /number="1" FT exon 699..968 FT /number="2" FT intron 969..1213 FT /number="2" FT exon 1214..1489 FT /number="3" FT intron 1490..2076 FT /number="3" FT exon 2077..2352 FT /number="4" FT intron 2353..2473 FT /number="4" FT exon 2474..2593 FT /number="5" FT intron 2594..3032 FT /number="5" FT exon 3033..3065 FT /number="6" FT intron 3066..3172 FT /number="6" FT exon 3173..3220 FT /number="7" FT intron 3221..3384 FT /number="7" FT exon 3385..3389 FT /number="8" FT UTR 3390..4304 SQ Sequence 4304 BP; 832 A; 1199 C; 1301 G; 972 T; 0 other; ttattttgct ggatgtagtt taatattacc tgaggtaagg taaggcaaag agtgggaggc 60 agggagtcca gttcagggac ggggattcca ggagaagtga aggggaaggg gctgggcgca 120 gcctgggggt ctctccctgg tttccacaga cagatccttg gccaggactc aggcacacag 180 tgtgacaaag atgcttggtg taggagaaga ggaatcagga cgaagtccca ggtcccgggc 240 ggggctctca gggtctcagg ctccaagggc cgtgtctgca ctggggaggc gccgcgttga 300 ggattctcca ctcccctgag tttcacttct tctcccaacc tgcgtcgggt ccttcttcct 360 gaatactcat gacgcgtccc caattcccac tcccattggg tgtcggattc tagagaagcc 420 aatcagcgtc tccgcagtcc cggttctgaa gtccccagtc acccacccgg actcagattc 480 tccccagacg ccgagatgcg ggtcatggcg ccccgaaccc tcatcctgct gctctcggga 540 gccctggccc tgaccgagac ctgggcctgt gagtgcgggg ttgggaggga atcggcctct 600 gcggagagga gcgaggggcc cgcccggcga gggcgcagga cccggggagc cgcgccggga 660 ggagggtcgg gcgggtctca gcccctcctc gcccccaggc tcccactcca tgaggtattt 720 ctacaccgcc gtgtcccggc ccggccgcgg agagccccgc ttcatcgcag tgggctacgt 780 ggacgacacg cagttcgtgc ggttcgacag cgacgccgcg agtccgagag gggagccgcg 840 ggcgccgtgg gtggagcagg aggggccgga gtattgggac cgggagacac agaagtacaa 900 gcgccaggca cagactgacc gagtgagcct gcggaacctg cgcggctact acaaccagag 960 cgaggccagt gagtgacccc ggcccggggc gcaggtcacg acccctcctc atcccccacg 1020 gacggcccgg gtcgccccaa gtctcccggt ctgagatcca ccccgaggct gcggaacccg 1080 cccagaccct cgaccggaga gagccccagt cacctttacc cggtttcatt ttcagtttag 1140 gccaaaatcc ccgcgggttg gtcggggcgg ggcggggctc gggggacggg gctgaccgcg 1200 ggggcggggc cagggtctca catcatccag aggatgtatg gctgcgacgt ggggcccgac 1260 gggcgcctcc tccgcgggta tgaccagtac gcctacgacg gcaaggatta catcgccctg 1320 aacgaggatc tgcgctcctg gaccgccgcg gacacggcgg ctcagatcac ccagcgcaag 1380 tgggaggcgg cccgtgaggc ggagcagctg agagcctacc tggagggcct gtgcgtggag 1440 tggctccgca gatacctgaa gaatgggaag gagacgctgc agcgcgcggg taccaggggc 1500 agtggggagc cttccccatc tcctgtagat ctcccgggat ggcctcccac gaggagggga 1560 ggaaaatggg atcagcgcta gaatatcgcc ctcccttgaa tggagaatgg gatgagtttt 1620 cctgagtttc ctctgagggc cccctctgct ctctaggaca attaagggat gaagtccttg 1680 aggaaatgga ggggaagaca gtccctagaa tactgatcag gggtcccctt tgaccacttt 1740 gaccactgca gcagctgtgg tcaggctgct gacctttctc tcaggccttg ttctctgcct 1800 cacgctcaat gtgtttgaag gtttgattcc agcttttctg agtccttcgg cctccactca 1860 ggtcaggacc agaagtcgct gttcctccct cagagactag aactttccaa tgaataggag 1920 attatcccag gtgcctgtgt ccaggctggc gtctgggttc tgtgccccct tccccacccc 1980 aggtgtcctg tccgttctca ggatggtcac atgggcgctg ttggagtgtc gcaagagaga 2040 tacaaagtgt ctgaattttc tgactcttcc cgtcagaaca cccaaagaca cacgtgaccc 2100 accatcccgt ctctgaccat gaggccaccc tgaggtgctg ggccctgggc ttctaccctg 2160 cggagatcac actgacctgg cagtgggatg gggaggacca aactcaggac actgagcttg 2220 tggagaccag gccagcagga gatggaacct tccagaagtg ggcagctgtg gtggtgcctt 2280 ctggagaaga gcagagatac acgtgccatg tgcagcacga ggggctgccg gagcccctca 2340 ccctgagatg gggtaaggag ggggatgagg ggtgatgtgt cttctcaggg aaagcagaag 2400 tcctggagcc cttcagccag gtcagggctg aggcttgggg gtcagggccc ctcaccttcc 2460 cctcctttcc cagagccgtc ttcccagccc accatcccca tcgtgggcat cgttgctggc 2520 ctggctgtcc tggctgtcct agctgtccta ggagctgtgg tggctgttgt gatgtgtagg 2580 aggaagagct caggtaggga aggggtgagg agtggggtct gggttttctt gttccactgg 2640 gagtttcaag ccccaggtag aagtgtgccc cacctcgtta ctggaagcac catccacaca 2700 tgggccatcc cagcctggga ccctgtgtgc cagcacttac tctgttgtga agcacatgac 2760 aatgaaggac agatgtatca ccttgatgat tatggtgttg gggtccttga ttccagcatt 2820 catgagtcag gggaaggtcc ctgctaagga cagaccttag gagggcagtt gctccagaac 2880 ccacagctgc tttccccgtg tttcctgatc ctgccctggg tctgcagtca tagttctgga 2940 aacttctctt gggtccaaga ctaggaggtt cccctaagat cgcatggccc tgactcctcc 3000 ctgtcccctc acagggcatt ttcttcccac aggtggaaaa ggagggagct gctctcaggc 3060 tgcgtgtaag tgatggcggt gggcgtgtgg aggagctcac ccaccccata attcctcttg 3120 tcccacatct cctgcgggct ctgaccaggt cttttttttt gttctacccc agccagcaac 3180 agtgcccagg gctctgatga gtctctcatc gcttgtaaag gtgagattct ggggagctga 3240 agtggtcggg ggtggggcag agggaaaagg cctaggtaat ggggatcctt tgattgggac 3300 gtttcgaatg tgtggtgagc tgttcagagt gtgatcactt accatgactg acctgaattt 3360 gttcatgact attgtgttct gtagcctgag acagctgcct gtgtgggact gagatgcagg 3420 atttcttcac acctctcctt tgtgacttca agagcctctg gcatctcttt ctgcaaaggc 3480 atctgaatgt gtctgcgttc ctgttagcat aatgtgagga ggtggacaga cagcccaccc 3540 ccgtgtccac cgtgacccct gtccccacac tgacctgtgt tccctccccg atcatctttc 3600 ctgttccaga gaagtgggct ggatgtctcc atctctgtct caacttcatg gtgcgctgag 3660 ctgcaacttc ttacttccct aatgaagtta ggaacctgaa tataaatttg ttttctcaaa 3720 tatttgctat gaagggttga tggattaatt aaataagtca attcctggaa gttgagagag 3780 caaataaaga cctgagaact ttccagaatc cgcatgttct ctgtgctgag tctgttgcag 3840 gtgggggtgg ggaaggctgt gaggagccga gtgtggacgg gggcctgtgc ctagttgctg 3900 ttcagttctt catgggcttt atgtagtcag tccttagctg ggtcaccttc actgctccat 3960 tgtccttgtc ccttcagtgg aaacttgtcc agcaggagct gtgaccacag aggctcacac 4020 atcgcccagg gcagcccctg cacacgggag tccctgtgct ttctgagaca aattttcaga 4080 cccattcagc tcctgccctc cttatagggc tcctcttctg ctttggtctc ctgccctctc 4140 tcccttccct gattccagtg atcttcgtgc tgactccaat cccaactcat gaatctaaag 4200 cagagcctaa tttagatttg tatttgtttg taaaattggg tccatagtct agaattgttc 4260 cttcctgaag agagaaacct gatcgtgtgc tgcagcgtgc aggg 4304 //