Dbfetch
ID HLA00959; SV 3; standard; DNA; HUM; 2061 BP. XX AC HLA00959; XX SV HLA00959.3 XX DT 03-MAR-1993 (Rel. 1.0.0, Created, Version 1) DT 16-JAN-2024 (Rel. 3.55.0, Last Updated, Version 3) XX DE TAP2*01:01:01, Human ABC (ATP Binding Cassette) Transporter gene XX KW Human MHC; ABC Transporter; TAP2; Allele; TAP2*01:01:01; XX OS Homo Sapiens (human) OC Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates; OC Catarrhini; Hominidae; Homo. XX CC -------------------------------------------------------------------------- CC IPD-IMGT/HLA Release Version 3.55.0 CC -------------------------------------------------------------------------- CC Copyrighted by the IPD-IMGT/HLA Database, Distributed under the Creative CC Commons Attribution-NoDerivs License, see; CC http://www.ebi.ac.uk/ipd/imgt/hla/licence/ for further details. CC -------------------------------------------------------------------------- XX RN [1] RP 1-2061 RX PUBMED; 1741401. RA Powis SH, Mockridge I, Kelly A, Kerr LA, Glynne R, Gileadi U, Beck S, RA Trowsdale J; RT "Polymorphism in a second ABC transporter gene located within the class II RT region of the human major histocompatibility complex."; RL Proceedings of the National Academy of Sciences USA 89:1463-1467(1992). XX CC -------------------------------------------------------------------------- CC The sequence below is the official allele sequence as approved by the CC WHO Nomenclature Committee for Factors of the HLA System. CC Any cross references may differ from the sequence shown below. CC -------------------------------------------------------------------------- XX DR EMBL; M84748; M84748.1. XX FH Key Location/Qualifiers FH FT source 1..2061 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT /ethnic="European" FT /cell_line="CEM-CCRF" FT CDS join(1..493,494..608,609..739,740..945,946..1143, FT 1144..1272,1273..1461,1462..1635,1636..1795,1796..1932, FT 1933..2061) FT /codon_start=1 FT /gene="TAP2" FT /allele="TAP2*01:01:01" FT /product="ABC Transporter TAP2*01:01:01 sequence" FT /translation="MRLPDLRPWTSLLLVDAALLWLLQGPLGTLLPQGLPGLWLEGTLR FT LGGLWGLLKLRGLLGFVGTLLLPLCLATPLTVSLRALVAGASRAPPARVASAPWSWLLV FT GYGAAGLSWSLWAVLSPPGAQEKEQDQVNNKVLMWRLLKLSRPDLPLLVAAFFFLVLAV FT LGETLIPHYSGRVIDILGGDFDPHAFASAIFFMCLFSFGSSLSAGCRGGCFTYTMSRIN FT LRIREQLFSSLLRQDLGFFQETKTGELNSRLSSDTTLMSNWLPLNANVLLRSLVKVVGL FT YGFMLSISPRLTLLSLLHMPFTIAAEKVYNTRHQEVLREIQDAVARAGQVVREAVGGLQ FT TVRSFGAEEHEVCRYKEALEQCRQLYWRRDLERALYLLVRRVLHLGVQMLMLSCGLQQM FT QDGELTQGSLLSFMIYQESVGSYVQTLVYIYGDMLSNVGAAEKVFSYMDRQPNLPSPGT FT LAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQ FT NLYQPTGGQVLLDEKPISQYEHCYLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKV FT MAAAQAAHADDFIQEMEHGIYTDVGEKGSQLAAGQKQRLAIARALVRDPRVLILDEATS FT ALDVQCEQALQDWNSRGDRTVLVIAHRLQTVQRAHQILVLQEGKLQKLAQL" FT exon 1..493 FT /number="1" FT exon 494..608 FT /number="2" FT exon 609..739 FT /number="3" FT exon 740..945 FT /number="4" FT exon 946..1143 FT /number="5" FT exon 1144..1272 FT /number="6" FT exon 1273..1461 FT /number="7" FT exon 1462..1635 FT /number="8" FT exon 1636..1795 FT /number="9" FT exon 1796..1932 FT /number="10" FT exon 1933..2061 FT /number="11" SQ Sequence 2061 BP; 385 A; 570 C; 646 G; 460 T; 0 other; atgcggctcc ctgacctgag accctggacc tccctgctgc tggtggacgc ggctttactg 60 tggctgcttc agggccctct ggggactttg cttcctcaag ggctgccagg actatggctg 120 gaggggaccc tgcggctggg agggctgtgg gggctgctaa agctaagagg gctgctggga 180 tttgtgggga cactgctgct cccgctctgt ctggccaccc ccctgactgt ctccctgaga 240 gccctggtcg cgggggcctc acgtgctccc ccagccagag tcgcttcagc cccttggagc 300 tggctgctgg tggggtacgg ggctgcgggg ctcagctggt cactgtgggc tgttctgagc 360 cctcctggag cccaggagaa ggagcaggac caggtgaaca acaaagtctt gatgtggagg 420 ctgctgaagc tctccaggcc ggacctgcct ctcctcgttg ccgccttctt cttccttgtc 480 cttgctgtct tgggtgagac attaatccct cactattctg gtcgtgtgat tgacatcctg 540 ggaggtgatt ttgaccccca tgcctttgcc agtgccatct tcttcatgtg cctcttctcc 600 tttggcagct cactgtctgc aggctgccga ggaggctgct tcacctacac catgtctcga 660 atcaacttgc ggatccggga gcagcttttc tcctccctgc tgcgccagga cctcggtttc 720 ttccaggaga ctaagacagg ggagctgaac tcacggctga gctcggatac caccctgatg 780 agtaactggc ttcctttaaa tgccaatgtg ctcttgcgaa gcctggtgaa agtggtgggg 840 ctgtatggct tcatgctcag catatcgcct cgactcaccc tcctttctct gctgcacatg 900 cccttcacaa tagcagcgga gaaggtgtac aacacccgcc atcaggaagt gcttcgggag 960 atccaggatg cagtggccag ggcggggcag gtggtgcggg aagccgttgg agggctgcag 1020 accgttcgca gttttggggc cgaggagcat gaagtctgtc gctataaaga ggcccttgaa 1080 caatgtcggc agctgtattg gcggagagac ctggaacgcg ccttgtacct gctcgtaagg 1140 agggtgctgc acttgggggt gcagatgctg atgctgagct gtgggctgca gcagatgcag 1200 gatggggagc tcacccaggg cagcctgctt tcctttatga tctaccagga gagcgtgggg 1260 agctatgtgc agaccctggt atacatatat ggggatatgc tcagcaacgt gggagctgca 1320 gagaaggttt tctcctacat ggaccgacag ccaaatctgc cttcacctgg cacgcttgcc 1380 cccaccactc tgcagggggt tgtgaaattc caagacgtct cctttgcata tcccaatcgc 1440 cctgacaggc ctgtgctcaa ggggctgacg tttaccctac gtcctggtga ggtgacggcg 1500 ctggtgggac ccaatgggtc tgggaagagc acagtggctg ccctgctgca gaatctgtac 1560 cagcccacag ggggacaggt gctgctggat gaaaagccca tctcacagta tgaacactgc 1620 tacctgcaca gccaggtggt ttcagttggg caggagcctg tgctgttctc cggttctgtg 1680 aggaacaaca ttgcttatgg gctgcagagc tgcgaagatg ataaggtgat ggcggctgcc 1740 caggctgccc acgcagatga cttcatccag gaaatggagc atggaatata cacagatgta 1800 ggggagaagg gaagccagct ggctgcggga cagaaacaac gtctggccat tgcccgggcc 1860 cttgtacgag acccgcgggt cctcatcctg gatgaggcta ctagtgccct agatgtgcag 1920 tgcgagcagg ccctgcagga ctggaattcc cgtggggatc gcacagtgct ggtgattgct 1980 cacaggctgc agacagttca gcgcgcccac cagatcctgg tgctccagga gggcaagctg 2040 cagaagcttg cccagctcta g 2061 //