Dbfetch
ID HLA00685; SV 4; standard; DNA; HUM; 14956 BP. XX AC HLA00685; XX SV HLA00685.4 XX DT 21-NOV-1987 (Rel. 1.0.0, Created, Version 1) DT 16-JAN-2024 (Rel. 3.55.0, Last Updated, Version 4) XX DE HLA-DRB1*04:01:01:01, Human MHC Class II sequence XX KW Human MHC; HLA; Class II; HLA-DRB1; Allele; HLA-DRB1*04:01:01:01; XX OS Homo Sapiens (human) OC Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates; OC Catarrhini; Hominidae; Homo. XX CC -------------------------------------------------------------------------- CC IPD-IMGT/HLA Release Version 3.55.0 CC -------------------------------------------------------------------------- CC Copyrighted by the IPD-IMGT/HLA Database, Distributed under the Creative CC Commons Attribution-NoDerivs License, see; CC http://www.ebi.ac.uk/ipd/imgt/hla/licence/ for further details. CC -------------------------------------------------------------------------- XX RN [1] RP 1-14956 RX PUBMED; 3860851. RA Spies T, Sorrentino R, Boss JM, Okada K, Strominger JL; RT "Structural organization of the DR subregion of the human major RT histocompatibility complex."; RL Proceedings of the National Academy of Sciences USA 82:5165-5169(1985). XX RN [2] RP 1-14956 RX PUBMED; 3036826. RA Andersson G, Larhammar D, Widmark E, Servenius B, Peterson PA, Rask L; RT "Class II genes of the human major histocompatibility complex. Organization RT and evolutionary relationship of the DR beta genes."; RL Journal of Biological Chemistry 262:8748-8758(1987). XX RN [3] RP 1-14956 RX PUBMED; 3467350. RA Curtsinger JM, Hilden JM, Cairns JS, Bach FH; RT "Evolutionary and genetic implications of sequence variation in two RT nonallelic HLA-DR beta-chain cDNA sequences."; RL Proceedings of the National Academy of Sciences USA 84:209-213(1987). XX RN [4] RP 1-14956 RX PUBMED; 21388356. RA Zhu F, He Y, Tao S, Zhang W, He J, He J, Xu X, Lv H, Yan L; RT "Analysis of the complete cDNA sequences of HLA-DRB1 alleles with group RT specific amplification primers in the Chinese Han population."; RL Tissue Antigens 77:329-332(2011). XX RN [5] RP 1-14956 RX PUBMED; 35094503. RA Turner TR, Hayward DR, Gymer AW, Barker DJ, Leen G, Cambridge CA, RA Macpherson HL, Georgiou X, Cooper MA, Robinson J, Mayor NP, Marsh SGE; RT "Widespread non-coding polymorphism in HLA class II genes of International RT HLA and Immunogenetics Workshop cell lines."; RL HLA 99:328-356(2022). XX CC -------------------------------------------------------------------------- CC The sequence below is the official allele sequence as approved by the CC WHO Nomenclature Committee for Factors of the HLA System. CC Any cross references may differ from the sequence shown below. CC -------------------------------------------------------------------------- XX DR EMBL; AF029267; AF029267.1. DR EMBL; HM067845; HM067845.1. DR EMBL; K02776; K02776.1. DR EMBL; LR813395; LR813395.1. DR EMBL; LR813401; LR813401.1. DR EMBL; LR813405; LR813405.1. DR EMBL; LR813406; LR813406.1. DR EMBL; LR813449; LR813449.1. DR EMBL; LT220230; LT220230.2. DR EMBL; M20548; M20548.1. DR EMBL; M20549; M20549.1. DR EMBL; M20550; M20550.1. XX FH Key Location/Qualifiers FH FT source 1..14956 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT /ethnic="Asian, European, Undefined" FT /cell_line="9000610018256U" FT /cell_line="BOLETH" FT /cell_line="BSM" FT /cell_line="C.M.L." FT /cell_line="DEM" FT /cell_line="DEU" FT /cell_line="LTC" FT /cell_line="MJ4" FT /cell_line="PRIESS" FT /cell_line="SAVC" FT CDS join(573..672,8930..9199,12654..12935,13633..13743, FT 14216..14239,14868..14881) FT /codon_start=1 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*04:01:01:01" FT /product="MHC Class II HLA-DRB1*04:01:01:01 sequence" FT /translation="MVCLKFPGGSCMAALTVTLMVLSSPLALAGDTRPRFLEQVKHECH FT FFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQKRAAV FT DTYCRHNYGVGESFTVQRRVYPEVTVYPAKTQPLQHHNLLVCSVNGFYPGSIEVRWFRN FT GQEEKTGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSLTSPLTVEWRARSE FT SAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS" FT UTR 1..572 FT exon 573..672 FT /number="1" FT intron 673..8929 FT /number="1" FT exon 8930..9199 FT /number="2" FT intron 9200..12653 FT /number="2" FT exon 12654..12935 FT /number="3" FT intron 12936..13632 FT /number="3" FT exon 13633..13743 FT /number="4" FT intron 13744..14215 FT /number="4" FT exon 14216..14239 FT /number="5" FT intron 14240..14867 FT /number="5" FT exon 14868..14881 FT /number="6" FT UTR 14882..14956 SQ Sequence 14956 BP; 4017 A; 3045 C; 3360 G; 4534 T; 0 other; gaaagacctg aaagatcacg gtgccttcat tttaactgtg agacatgaag taattttccc 60 aagtctacaa cagtaagata tggtgcaata aggaccagat taaaagtctc ctgatttgca 120 accatgttcc ctccatctcc tttactccta agcacactca cacactcact cctgcaaaca 180 attctcttgt caagtgggaa atgaatgctc ttacaaggct caaatttgtg aacacatcac 240 tgaccagcac agagctggct aacaataggg acacaattaa ggtgttttac acgcaactgg 300 ttcaaacctt tcaagtacta aattaaaaca atcctttaaa gaaggaaatt gtttcagaaa 360 aggaccttca tacagcatct ctgaccagcg actgatgatg ctattgtact cagatgctga 420 ttcgttctcc aacactagat tacccaatcc acgagcaagg aaatcagtaa cttcttccct 480 ataatttgga atgtgggtgg agaggggtca tagttctccc tgagtgagac tcacctgctc 540 ctctggcccc tggtcctgtc ctgttctcca gcatggtgtg tctgaagttc cctggaggct 600 cctgcatggc agctctgaca gtgacactga tggtgctgag ctccccactg gctttggctg 660 gggacacccg acgtaagtgc acattgtggg tgctgaccta ctatggggtg gggaaaaaag 720 ggagttgtgt taacattgtg cccaggccat gtcccttaag aaagtgtgac attttcttca 780 gggattgccc atctttatca tatggatccc aaattatttc caccacaaat ggaacttggc 840 tacttgccct attcatgaga ctgtgtaaag ggcctttgta caggccatgt tttactttaa 900 atctctacca ataaaacctt tgcatcacat gtcctcaggg tctttagagg atttagaaat 960 aaggatgcta aaataaattc ctcatacagc acttcccttt atcatgttga cttatgtcag 1020 acgaaacaag gttttgtttt gaaaattttg tgggagtcaa aggaattcaa agggtctctc 1080 ctagacgatc ctgtgttgtc ctccacagga cctgtggtgt tggcccctct tcctcatatg 1140 tgaggatgta cccagtggcc tccccattgt ttcctttctt ttttttctga actccagtgt 1200 ttataaagcc tgtatccctg tagcatatgt aggttctctg acagaagtta tacttagtgc 1260 tctttctttc ttatggggaa aaatccctgg atctgaaact gacatcttta gtacttggag 1320 tcaccctaca ggtaaagacc atttatgagg tattcattgg tgcctcctct tgatcggtct 1380 ctcagacccc tgaatacttg gatactcctc aagaacttaa ggcatcctct gaaaaactgg 1440 cccagattag tgcttattat taatctttta taacctttct atacttgttt ctcctgcatg 1500 ctctaactag acatgacaga agagattcaa ctaacatagg ataaattata tgaaattcta 1560 tttttgtaag tcaaaaatag tcaaatacca gaaaattaat aatgttcaaa ctatatactc 1620 tgtgtggggt taccgagacg acgtggacat tgttcacatc taatagggct gaaagtcaat 1680 gaagaagtcc tggaaactcc ttgtcttact ggggtcttgt cctaaatttc ataggttcac 1740 ccatcatgcc ctcagctttc cttaattagc catgtctgct tatctctacc tccagtttct 1800 ctctattttt ccccagctat gttgtcatca tttccagaaa tctctaaaac ttgcaaagat 1860 ccttagcact atgagatcca ttgaaagaga taattttttt ctttttgaga cagggcttgg 1920 ttctgtcacc caggctgtag tgcagtggtg tgatctaggc tcactgcaac ctctgcttcc 1980 cacgctcaag tgatcctccc tcctcagcct ccagagtagc ggagactaca ggcaggcaaa 2040 catgtgcagc taattttcat gattttgtta gagatgagat tttgccatgt tgcccaggct 2100 gttcttaaac tcctggactc aagcaatcct cctgccttag cctcccaata tgctaggatt 2160 atagatgtga gccattgtgc ccaggcaaaa agagatgaac cttaatttaa aaatttcctt 2220 tttcttaaat cactgtttct ctatctgtga attcttcttc caactagaag gaggagaaag 2280 aagaagtttg cctgtatttc tcaccaggag gaggagtcta gtgtgatatc aaaatgaaag 2340 agtgctggag cttgatcccc ttcttgcttt ccaggatccc tgcagtgatc agttcccaca 2400 ccctggttta ttcatgtaaa gcacacttat ttttttcagc agctactctt tactgggctc 2460 cattctaagt tcaaatcatt ctatttgagt aagatagaga gggtcccgac tctcatggaa 2520 gttacacaag agtagaggag acagacacta acccaataag catttaacaa agaagaaaat 2580 gttagagaga catagtgcac tgaagaaaag acatcaggtt tgtgaaaaag agagacatgg 2640 attcacttac tttggttcat atgcttaggc agctataact gagaaagtga cattcagctg 2700 agacaacaaa ataaatagac agtcgtgaag atctaaagga cgaaagttcc agggagaatg 2760 aatggggggg aagctctggt gtgggaaatt atgtggaagg acagaaagaa ggctagaggg 2820 actgaactat agcaagcaag gaaatggaga ggcagaagat gaggtaggac acagagagga 2880 agtcaggagc ctcatcatat tagactctga tggccatggt aaaaaaattg aattttattt 2940 tatttttatt tattttttga gacggagatt tgttcttgtt gcccaggctg gagtgcaatg 3000 gcgcgatctc gactcactgc aacctctgcc tcctgggttc aagtgattct cctgcctcag 3060 cttcccaagt agctgggatt acaggtgcct gcgaccatac tcggcttatt tttttgtatt 3120 tttagtagag acagggtatc accatgttgg ccaggctggt ctcaaactcc tgacctcaga 3180 taatctgcct ggcttcccaa agtgctgaga ttacaggcgt gagccaccat gcccaacctg 3240 aattttattt gaatagatat gagaagctac tgtatggtta caaggacagt caatttatat 3300 tcgatttttt ttttttgaga cagagtcttg ctctgttgcc caggctagat tgcagtggta 3360 caatctcagc tcactgcaac ctctgcctcc tgggttccag caattctcct gcctcagcct 3420 cccaagtagc tgagaccaca ggtacatgcc actacacctg gctaattttt tgtattttta 3480 gtagagatgg ggtttcaccg tgttagccag gatggtcttg atctcctgac ctcgtgatcc 3540 actcccctcg gcctcccaaa gtgctgggat tacaggtgtg agccaccacg cccggcctat 3600 attcaattat taaaattaat tctagctact ctgtggggat tggattgttg ggtttcacaa 3660 gtggtcagga agactattta ggatcacagc agggaattct ccagggaaaa caggcttgtg 3720 gcttcataga gtgcattagt gataaagaca gtgaaaacga caaagtggac agactaggca 3780 tgtatttttg cttagcttgt taatggatta ctctaaaggg ggtagaaaaa tcaagcttat 3840 tcctaaggat tttgttttga caaataagtg gatggtggtg tttattgaga taggaaaaac 3900 tgtgggagga aatgatttga agtgggtggt tggaaataaa agttttgttt aaatttgaga 3960 tgatttattg acatttatgt ggagcaatcc gaaggtcaat ggcatttaag agactcatgg 4020 tgaggtgagg ccagggcttc aggtatttat gttggcggca tcagtacgtg taatgtgtta 4080 aattccaggg agtggaagag gatacatagg gagatggatt gtgtggagaa aaaagaagag 4140 ggtacaggcc agcaaagggg gctgagacag agcccaggga tgctggagaa aacccaagag 4200 aacataatgg gtgtaagtca tggaaaatag attattttca aggagaaggg agaggtcaat 4260 tgtggtgagt accactaaga ggagggggaa gtgagaacgt gacagagaag caagtgctgg 4320 gtttgctgga gttgatattt gcagtcaatg gagtatccag ggaggaaact ggattggacc 4380 atttgaagag caagtagaag tgaggacgag gttaagggtg actattttaa gtagagagct 4440 tcagggaagg actgtgctct gggttcaggg agcctgctgg atctaaagga aaagggctga 4500 agaggctgaa gagaaggagg aggacctgtg aaccagagat actgagttat tattagcaag 4560 gaaatactag agggtccctg tgtgcagtgc tgactgctca tgcaaaaggt cacacagaca 4620 atatttcaca cagccagtat ttattagtga catagaatat gccagttatt actctaggtc 4680 atgagaatag agtgataaat aaaatgaatc tggtcgccat cggtatatgc catgtaacat 4740 tttgcagtga ctgtgtacca ggcctatgaa tttcagtatg caatttcaat aacgatcctg 4800 ttgtatctgt ggtgtttaaa aacatataca tctctggaat ctaaaattga gaggatataa 4860 gtaaaaccca gtattagaaa tttagtgctg gaaatcagac tgcagtttaa atctgagcat 4920 atagaaagtc cctttcttct atgtcagcag atgccttttg tgtgaggttt aggtatacta 4980 cattattaga cataaaccag tgattctgcc ctatgttttc agaatgacaa ttctttatga 5040 aactaataga agaacagaag acaattgcaa aatcatgatg aagatgctag tggctttaga 5100 accaaggaat acaaaaaata atgtgagctg cagttatagg gattataaaa gttaaaatgg 5160 gaatgcattt gagtgtttat tatgtgatca gtgctaataa gagtcatcat ttaattttac 5220 acttaacaat aatcctgtga ggattaagct attattaaat gcatttgata gattacaaaa 5280 aggcttaccg ttggtaaaaa ttgacccaag gggaagaggt cacattttta ttcagatttt 5340 ctgattctag agtttgagag tctgtccatc attagtgagt agtgacaata ctgtgtctaa 5400 attatcgaca gaatttctga tattcatatg tactatgttg tttcttagag tgtgggcaga 5460 gattcagggc tgctagttcc aatgtatagg agaaactttc attcattgtg catttatcat 5520 tttaaaagtt ctaggctggg tgcggtggct catgcctgta atcccagcac tttgggaggc 5580 caaggcgggc agatcacgag gtcaggagat gaagaccatc ctggctaaca tggtgaaacc 5640 tcgtctctac taaaaataca aaaaattagc tgggcgtggt ggtgtgcacc tgtagtccca 5700 gctacttggg aggctgaggc aggagaatgg catgaacctg ggaggcggag cttgcagtga 5760 gctgagatcg tgccactgca ctccagctcc accctgggca aaagagcgaa actccgtctc 5820 aaaaaaaaaa aaaagttcta tatgtctgtc atggcatatg ttgaagaaca caaggaagta 5880 ttaaatcact ccttctgagg tttgtctagc aagttgggct aggattgcca aataaaatac 5940 aggtttctag ttaaatctga atttcagata cacaactata atttactgaa aatccaaatg 6000 taacttggca tcctctgatt ttatttgcca aatctgtcaa ccctacatga gacacatgag 6060 catggattac ggtgttaccc atggaagcca cagccacagt gacagcgact tcacacatgt 6120 ttatttttta actttctctc tgtaaagaaa gtgcttagat aatttaggga taaaaagata 6180 gacattgttt gatccaggat gcactcctct ctgccatcgt ttctaaaggg caaagagaga 6240 tttccacagg tcttactcac agtctgactc acagtctggg gacctgctca tgctttgaaa 6300 ctgtctgtat gagaatgtca ttttcttggt ttctcccttt ctgaggggac ttgactacaa 6360 aactgagagt tctacctctg gccaaggctg gaaatttgat gcctgctagt attgttggga 6420 atgggagact gaaataaatg agttagttgg ggcattaaac aggaataaaa tagctgtggt 6480 tgtgattcat tactacaatt agtggactag tggcagagaa attaagaaag aagatgatgt 6540 gagagataaa ttatatgatt tggtaaggca agggaatcag taaatcttgg ttctgaacaa 6600 gttcattttc tggaaagata gcactgtact gggaccagaa ttctacaaaa catccgtttt 6660 atgtaagacc aagattttca acaaatattt ttcaatgcag ttctcagctg ctccataact 6720 aatagtgact tattcaacac agatattttc agatggttca cacccatgtt tcttacccag 6780 ggacagttca ccacccctcc ccttccctcc catcactctt gaggaacatg tggcaatgtt 6840 agaataattt ttggttgtca caacaggggt ttcttctgat atttaatgag cagaagccag 6900 ggacactgct agagaaccca caatgttcag aatagactcc atcaccaacc aagatttatc 6960 tcgtccaaaa tgtcaatagt gctgaggctg gaagcattgg ttcacactgt gctctttctg 7020 aaaaatgtag actcgctttt tttttttttt tttttgagat ggggtcttgc tctgtcgccc 7080 agactggagt gcagtggctc catctcagct cactacaacc tctgcctccc aggttcaagc 7140 gattctcctg tctcagcctc cccagtagct gggattacag gtgcaccctg ccatgcccgg 7200 ctaatttttt gtattttagt agagatgggg tttcaccatg ttgcccaggc tggtctcgaa 7260 ctcctgagct caggcaatcc acccgctttg gtctcccaaa gtgctaggat tacacgcatg 7320 agccaccgcg cccggcctag actcacatct tttatacact tactgcccaa ttcagttctt 7380 tatggtttat ttttgcttgt ttcattataa aaaactagac agttgcataa attcaaccac 7440 ttacttgttg aatccattta gtcaatgcaa gctcaacatt ttcatattta ttttttgcct 7500 tatgcaatat tgttcaacat tttcataagt tgttggtcag cactatctct attaactttc 7560 aacagtttgc ccttctaagt cacaaatagt gatgctgctg caattatttt tcactaacat 7620 gcctcagatt tctgtagtga ttctacattt gatattattc acaatgtaaa atgcttctat 7680 ttattcattt cacttttacc cacaggatta tttttaagtt atttttgtca ttttcacact 7740 tcaaccaaac ataaagacaa aaacatcaaa aatatgtaca tagtgttata cataggtgta 7800 tatttacaca catatatgca catatgttta tatgtattga aactacagaa gcacatgtca 7860 ccaataagag ctctgagaca cctttgacca cttaccctta tcagatgaga tttgccaaat 7920 gagttttggg aacaaatttc ttttaactga atttctgagc tttgtggatt tagaaatgca 7980 actgaaagtt tgtggacatt tacgaggatc atagttttat tctccttaaa actcttcaat 8040 actttcccat tgtctttagt aaatccaaaa tcctaacacc actcacgagg cttttcaaca 8100 cctggcttct tgtgatttct ccaatctaac cttttaccct ccttcccctc agcctctctg 8160 ctttagtgaa ctttgttcta gttttttgaa gttcatcatc aattcaagct tttgtacatg 8220 ggatttccta aacctgaaat gtgcctccgg ttttgtccaa acagacacac aggctccact 8280 ctgccccctg gctcacacct gcttaacttg ttaagtcaca tctgtaactg tcactcttct 8340 ctggcaccct aaaggaattg agatcatcct attattctct gttctagaac tccacacttc 8400 tgaaatttct cattcctgtc taagctcttg tgtgtttggt ttttggccat cactttcact 8460 gctcttaaag ctcccccagc ggagtggaga ggtctgtttt cccgtgtttg gattcctaga 8520 ggcagcgcag gcctggcaca aggtcatcac taaggaagtg ttcacaggat gaaagcggtg 8580 cgtgctgttt aaggaaaggg taaagccttt aaatggtaaa gggttgagag aaggagcaaa 8640 gtgcctttgg ggtggaggct cccaggagga ggcggcgcgg gctgcggtgc tggacggatc 8700 ctcctccagc tcctgcctgg aggtctccag aacaggctgg aggcagggag ggggtcccaa 8760 aagccttggg atcagaggta gtttttccac ctggtccccc agacccccgt ccgcctcaga 8820 aagacagagg atgagcccct gggctgcgtg ttgtcggggt tgcgggtggg gccagatagt 8880 gtcttccccg gaggccgctt ctgtaaccgg atcgttcttg tccccccagc acgtttcttg 8940 gagcaggtta aacatgagtg tcatttcttc aacgggacgg agcgggtgcg gttcctggac 9000 agatacttct atcaccaaga ggagtacgtg cgcttcgaca gcgacgtggg ggagtaccgg 9060 gcggtgacgg agctggggcg gcctgatgcc gagtactgga acagccagaa ggacctcctg 9120 gagcagaagc gggccgcggt ggacacctac tgcagacaca actacggggt tggtgagagc 9180 ttcacagtgc agcggcgagg tgagcgcggc gcggggcggg gcctgagtcc ctgtgagcgg 9240 agaatctgag tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgagagagag 9300 agagagagag agagagagag agagcgccat ctgtgagcat ttagaatcct ctctatcctg 9360 agcaaggagt tctgcgggca caggtgtgtg tgtagagtgt ggatttgtcc gtgtctgtga 9420 ggctgttgtg ggaggggagg caggaggggg ctgcttctta ttcttggaga cttctgtggg 9480 gaggtgacaa gggaggtggg tgctgggggc tggagagaga ggcgaccttg attgtctcgg 9540 gtccttagag atgcaaggaa gggaaatgta tggggtgtgt ggttggggtg aaggtttagg 9600 ggaggagagc tgaggggtaa ggaaggtttg ggataatgtg aagaggccag tttcagactg 9660 tccctggcac acacccttca tgtaatctct gaaataaaag tgtgtgctgt ttgtttgtaa 9720 aagcattaga ttaacttcta ggggaattga gtagacctct gaggcacctc tgaagcttct 9780 ttaggtataa atttcttgct agttttttgt tttcttagtg ttatattttt acatagttga 9840 aatgactgtg aaactaactt tttgaattaa agtttgaaaa cactgttact attttattat 9900 aatgctaata atttcatagt tactttttaa atatataata gttgtgacac aaattacctc 9960 actttctttg tttttttttt tcttacactt taagttttag ggtacatgtg cacaacgtgc 10020 aggtttgtta catatgtata catgtgccat gttggtgtgc tgcacccatt aactcgtcat 10080 ttaacattag gtatatctcc taatgctatc cctccccacc cccccacccc acaacaggcc 10140 ccagtgtgtg atgttcccct tcctgtgtcc atgtgttctc actgttcaat tcccacctat 10200 gagtgagaac atgcggtgtt cggttttttg tccttgccat agtttgctga gaatgatggt 10260 ttccagcttc atccatgtcc ctacaaagga catgaactca ttcttttttg tggctgcata 10320 gtattccata gtgtatatgt gccacatttt cttaatccag tctatcattg ttggacattt 10380 gggttggttc caagtctttg ctattgtgaa tagtgccgca ataaacatac atgtgcatat 10440 gtctttatag cagcatgatt tataatcctt gggttatata cccagtaatg ggatggctgg 10500 gtcaaatggt atttctagtt ctagatccct gaggaatcgc cacactgact tccacaatgg 10560 ttgaactagt ttagagtccc accaacaggg taaaagtgtt cctatttctc cacatcctct 10620 ccagcacctg ttgcttcctg actttttaat gatcgccatt ctaactggtg tgagatggta 10680 tctcattgtg gttttgattt gcaattctct gatggccagt gatgatgagc attttttcat 10740 gtgtcttttg gctgcataaa tgtcttcttt tgagaagtgt ctgttcatgt cctttgccca 10800 ctttttgatg gggtattttg tttttttctt gtaaatttgt ttgagttcat tgcagattct 10860 ggatattagc cctttgtcat atgagtagat tgcaaaaatt ttctcccatt ctgtaggttg 10920 cctcttcact ctgatggtag tttcttttgc tgtgcagaag ctctttagtt taattagatc 10980 ccatttgtcc attttggctt ttgttgccat tgcttttggt gttttagaca tgaagttctt 11040 gcccatgcct atgtcctgaa tggtattgcc taggttttct tctagggttt ttatggtttc 11100 aggtctaaca tttaagtctt taatccatct tgaattaatt tttgtataag caaattacgt 11160 cactttcccc attgatgacc tttattatga cattcaccaa tagttgaaaa tgtatgtttc 11220 tggttaattt ttgatttata tttttttgat ttgtaattat tttgaattat tttgacctat 11280 ttattggcca gttgtaatta ctgctctgct ctacgaatta cctgttgtat ttggtaggta 11340 atggacaatg atctattgtc tcttatcttt agggcttagt atttttctca gtgactttgt 11400 gggtttgttg tactgtaaga ttattaacac tttattgata tttgattcag tattttctcc 11460 agtttgtggt atgtatattt tgaaaattct tttccatgtt aagaatttga acatttttat 11520 ttaataaaat atattgcaaa atgttaatta atgattcaca aactagctca agtctaccat 11580 tttgtggtat tgatgtctcc aggtttctcc ttccttctta aaaaaaaatg tatttattga 11640 gagtatgcta gtgtcaggga tttccctagg cataagcact ccaagtaatg agtcccagac 11700 actgccttga tccaaatgtc attctggaaa gaaaaatcat tttacagtga taagcctaat 11760 aatagttata cttgttttgc ctgggagatg cattgatcag ctaaatgtaa atataagaac 11820 tttcaaaact aaaatgacgt tccttaatct ttctctctgc tttaggaatc atgctttctt 11880 aggaacttaa agatttggag aatcatttct gtctgtccca ccttcccagg agcataacca 11940 tttctgtggt gttctaaggt gtgagtgcat ggcagtagta ttcctaaaaa tccatattca 12000 gtttcctcat gtgccctact ccgtcccttt ctctatccac attgctttaa atcatatttt 12060 tctctcaagg tgtacaagga tgataaatag gtgccaagtg gagaacccaa gtgtgacgag 12120 ccctctcaca gtagaatgga gtgagaagct ttctgacctc ataaattgaa ggctatcgta 12180 attcattctt ttatatattt tacttgcatt aatcctcata taacctcaag aggtaaatta 12240 atataattat cctccattat tggagagaaa gttgagacac aaaagaatca aaaactcttc 12300 caggatcaac cagtaaaagg cagaccttgg atttgaacca ggcaacctgg ctcagaagtc 12360 agttttaatt accacactct gtactttcaa agatttgtaa acgctttgac aatgcatgtc 12420 aatttcaagc tatgaagagc caaacataat ttttcacaat atctctcaaa tctaatgggt 12480 ccccactata aagattaaat tccaggctga tgacactgtg aggccacatg gccagctgtg 12540 ctggaggcct gctcaaggcc agagcctagg tttacagaga agcagacaaa aagctaaaca 12600 aggagactta ctctgtctgc atgacttatt ccctctacct tgttttctcc tagtctatcc 12660 tgaggtgact gtgtatcctg caaagaccca gcccctgcag caccacaacc tcctggtctg 12720 ctctgtgaat ggtttctatc caggcagcat tgaagtcagg tggttccgga acggccagga 12780 agagaagact ggggtggtgt ccacaggcct gatccagaat ggagactgga ccttccagac 12840 cctggtgatg ctggaaacag ttcctcggag tggagaggtt tacacctgcc aagtggagca 12900 cccaagcctg acgagccctc tcacagtgga atggagtgag cagctttctg acttcataaa 12960 tttctcaccc accaagacgc gaactttact aatccctgag tatcaggctt ctcctatccc 13020 acatcctatt ttcatttgct ccacgttctc atctccatca gcacaggtca ctggggggta 13080 gccctgtaat actttctaga aacacctgta ccccctgggg aagcagtcat gcctgccagg 13140 caggagaggc tgtccctctt ttgaacctcc ccatgatgtc acaagtcggg gtcacctgct 13200 gtctgtgggc tccaggccct gcctctgggt ctgagactga gtttctggta ctgttgctct 13260 gagtcgtttg ttgtaatctg agaagaggag aagtataggg accttcctga catgagggga 13320 gtccaatctc agctccgcct tttattagat ctgtcactct aggcaactac ttaacctcat 13380 tgggtctcag gctttctgtt catcagatgt tgaagtcctg tcttacatca aggctgtaat 13440 atttgaatga gtttgatgac tgaaccttgt aactgttcag tgtgatttga aaacctttct 13500 caagaaatgg tcagttattt tagttcttgc agagcagcct tctttctcat tttcaaagct 13560 ctgaatctca aggtgtcaat taaagaggtt ccatttggga taaaaatcac taaacctggc 13620 ttcctctctc aggagcacgg tctgaatctg cacagagcaa gatgctgagt ggagtcgggg 13680 gcttcgtgct gggcctgctc ttccttgggg ccgggctgtt catctacttc aggaatcaga 13740 aaggtgagga gcctttggta gctggctgtc tccatacgct tttctggagg aggaactatg 13800 gctttgctga agttggttct cagcatatga atggccctgg ataaagcctc tctactccca 13860 aatgacctcc aatgttctgc aaatccagaa atcatcagtg catggttgct atgtcaaagc 13920 ataatagctt gtggcctaca gagataacag aaagattaac aggtataggt gctttggttg 13980 agatcgtgga gcaaattaag gaagagcaac taaagctaat acaattacac tggatcctgt 14040 gacagacact tcacacttca tgggtcacat ggtctgtttc tgctcctctc tgccctggct 14100 ggtgtgggtt gtggtgtcag agaactctca ggtgggagat ctggagctgg gacattgtgt 14160 tggaggacag atttgcttcc atatccttta agtgtatatc ttctcttttt cctaggacac 14220 tctggacttc agccaacagg taataccttt tcatcctctt taagaaacag atttggaggc 14280 caggcgcagt ggctcacgcc tgtaatccca gcactttggg aggccgaggc gggcgaatca 14340 tgaggtcagg agttcgagac cagcctgacc aacgtggtga aaccccgtct ctactaaaaa 14400 tacaaaaaaa aatcagtcgg gcgtggtggt gtgcgcctgt aatcccagct actcaggagg 14460 ccaaggcagg agaatcgctg gaacccagga ggcagaggtt gcagtgagcc gagattgggc 14520 cactgcactc cagcctaggt gacagagtga gaccccatct caaaaaaaca aaaaaaagaa 14580 agaaagaaac agatttcctt tccctagaat gatggtagag gtaataaggc atgagacaga 14640 agtaatagca aagacattgg atccaaattt ctgatcaggc aatttacacc agaactcctc 14700 ctctccactt agaaaaggcc tgtgctctgc aggagtattg actcatggag acttcagaac 14760 ttgtttttct tcttcctgca gtgctctcat ctgagtcctt gaaagagggc aaaataaact 14820 gttagtagag ccaggtctga aaacaacact ttcttgcgtc tctgcaggat tcctgagctg 14880 aagtgaagat gaccacattc aaggaagaac cttctgcccc agctttgcag gatgaaacac 14940 ttccccgctt ggctct 14956 //