Dbfetch
ID HLA00294; SV 1; standard; DNA; HUM; 2677 BP. XX AC HLA00294; XX SV HLA00294.1 XX DT 14-NOV-1991 (Rel. 1.0.0, Created, Version 1) DT 16-JAN-2024 (Rel. 3.55.0, Last Updated, Version 1) XX DE HLA-B*40:03:01:01, Human MHC Class I sequence XX KW Human MHC; HLA; Class I; HLA-B; Allele; HLA-B*40:03:01:01; XX OS Homo Sapiens (human) OC Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates; OC Catarrhini; Hominidae; Homo. XX CC -------------------------------------------------------------------------- CC IPD-IMGT/HLA Release Version 3.55.0 CC -------------------------------------------------------------------------- CC Copyrighted by the IPD-IMGT/HLA Database, Distributed under the Creative CC Commons Attribution-NoDerivs License, see; CC http://www.ebi.ac.uk/ipd/imgt/hla/licence/ for further details. CC -------------------------------------------------------------------------- XX RN [1] RP 1-2677 RX PUBMED; 1317015. RA Belich MP, Madrigal JA, Hildebrand WH, Zemmour J, Williams RC, Luz R, RA Petzl-Erler ML, Parham P; RT "Unusual HLA-B alleles in two tribes of Brazilian Indians."; RL Nature 357:326-329(1992). XX RN [2] RP 1-2677 RX PUBMED; 28266141. RA Li Z, Zou HY; RT "Full-length sequence of 3 HLA-B alleles, HLA-B*40:01:01, B*40:03 and RT B*40:40 confirmed by cloning and sequencing."; RL HLA 89:321-324(2017). XX CC -------------------------------------------------------------------------- CC The sequence below is the official allele sequence as approved by the CC WHO Nomenclature Committee for Factors of the HLA System. CC Any cross references may differ from the sequence shown below. CC -------------------------------------------------------------------------- XX DR EMBL; GQ161928; GQ161928.1. DR EMBL; KC789817; KC789817.1. DR EMBL; M84383; M84383.1. XX FH Key Location/Qualifiers FH FT source 1..2677 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT /ethnic="Asian, Hispanic or Latin American, Native American" FT /cell_line="GRC-138" FT /cell_line="MDA0000105" FT /cell_line="SZ-88" FT CDS join(1..73,203..472,717..992,1568..1843,1937..2053, FT 2495..2527,2634..2677) FT /codon_start=1 FT /gene="HLA-B" FT /allele="HLA-B*40:03:01:01" FT /product="MHC Class I HLA-B*40:03:01:01 sequence" FT /translation="MRVTAPRTLLLLLWGAVALTETWAGSHSMRYFHTSVSRPGRGEPR FT FITVGYVDDTLFVRFDSDATSPRKEPRAPWIEQEGPEYWDRETQISKTNTQTYRESLRN FT LRGYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHDQSAYDGKDYIALNEDLRSWTAADTA FT AQITQRKWEAARVAEQLRAYLEGECVEWLRRYLENGKETLQRADPPKTHVTHHPISDHE FT ATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRY FT TCHVQHEGLPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGK FT GGSYSQAACSDSAQGSDVSLTA" FT exon 1..73 FT /number="1" FT intron 74..202 FT /number="1" FT exon 203..472 FT /number="2" FT intron 473..716 FT /number="2" FT exon 717..992 FT /number="3" FT intron 993..1567 FT /number="3" FT exon 1568..1843 FT /number="4" FT intron 1844..1936 FT /number="4" FT exon 1937..2053 FT /number="5" FT intron 2054..2494 FT /number="5" FT exon 2495..2527 FT /number="6" FT intron 2528..2633 FT /number="6" FT exon 2634..2677 FT /number="7" SQ Sequence 2677 BP; 494 A; 796 C; 860 G; 527 T; 0 other; atgcgggtca cggcgccccg aaccctcctc ctgctgctct ggggggcagt ggccctgacc 60 gagacctggg ctggtgagtg cggggtcggc agggaaatgg cctctgtggg gaggagcgag 120 gggaccgcag gcgggggcgc aggacccggg gagccgcgcc gggaggaggg tcgggcgggt 180 ctcagcccct cctcgccccc aggctcccac tccatgaggt atttccacac ctccgtgtcc 240 cggcccggcc gcggggagcc ccgcttcatc accgtgggct acgtggacga cacgctgttc 300 gtgaggttcg acagcgacgc cacgagtccg aggaaggagc cgcgggcgcc atggatagag 360 caggaggggc cggagtattg ggaccgggag acacagatct ccaagaccaa cacacagact 420 taccgagaga gcctgcggaa cctgcgcggc tactacaacc agagcgaggc cggtgagtga 480 ccccggcccg gggcgcaggt cacgactccc catcccccac gtacggcccg ggtcgccccg 540 agtctccggg tccgagatcc gcccccgagg ccgcgggacc cgcccagacc ctcgaccggc 600 gagagcccca ggcgcgttta cccggtttca ttttcagttg aggccaaaat ccccgcgggt 660 tggtcggggc ggggcggggc tcggggggac ggggctgacc gcgggggcgg ggccagggtc 720 tcacaccctc cagagcatgt acggctgcga cgtggggccg gacgggcgcc tcctccgcgg 780 gcatgaccag tccgcctacg acggcaagga ttacatcgcc ctgaacgagg acctgcgctc 840 ctggaccgcc gcggacacgg cggctcagat cacccagcgc aagtgggagg cggcccgtgt 900 ggcggagcag ctgagagcct acctggaggg cgagtgcgtg gagtggctcc gcagatacct 960 ggagaacggg aaggagacgc tgcagcgcgc gggtaccagg ggcagtgggg agccttcccc 1020 atctcctata ggtcgccggg gatggcctcc cacgagaaga ggaggaaaat gggatcagcg 1080 ctagaatgtc gccctccctt gaatggagaa tggcatgagt tttcctgagt ttcctctgag 1140 ggccccctct tctctctagg acaattaagg gatgacgtct ctgaggaaat ggaggggaag 1200 acagtcccta gaatactgat caggggtccc ctttgacccc tgcagcagcc ttgggaaccg 1260 tgacttttcc tctcaggcct tgttctctgc ctcacactca gtgtgtttgg ggctctgatt 1320 ccagcacttc tgagtcactt tacctccact cagatcagga gcagaagtcc ctgttccccg 1380 ctcagagact cgaactttcc aatgaatagg agattatccc aggtgcctgc gtccaggctg 1440 gtgtctgggt tctgtgcccc ttccccaccc caggtgtcct gtccattctc aggctggtca 1500 catgggtggt cctagggtgt cccatgagag atgcaaagcg cctgaatttt ctgactcttc 1560 ccatcagacc ccccaaagac acacgtgacc caccacccca tctctgacca tgaggccacc 1620 ctgaggtgct gggccctggg cttctaccct gcggagatca cactgacctg gcagcgggat 1680 ggcgaggacc aaactcagga cactgagctt gtggagacca gaccagcagg agatagaacc 1740 ttccagaagt gggcagctgt ggtggtgcct tctggagaag agcagagata cacatgccat 1800 gtacagcatg aggggctgcc gaagcccctc accctgagat ggggtaagga gggggatgag 1860 gggtcatatc tcttctcagg gaaagcagga gcccttcagc agggtcaggg cccctcatct 1920 tcccttcctt tcccagagcc gtcttcccag tccaccgtcc ccatcgtggg cattgttgct 1980 ggcctggctg tcctagcagt tgtggtcatc ggagctgtgg tcgctgctgt gatgtgtagg 2040 aggaagagct caggtaggga aggggtgagg ggtggggtct gggttttctt gtcccactgg 2100 gggtttcaag ccccaggtag aagtgttccc tgcctcatta ctgggaagca gcatccacac 2160 aggggctaac gcagcctggg accctgtgtg ccagaactta ctcttttgtg cagcacatgt 2220 gacaatgaag gacggatgta tcaccttggt ggttgtggtg ttggggtcct gattccagca 2280 ttcatgagtc aggggaaggt ccctgctaag gacagacctt aggagggcag ttggtccagg 2340 acccacactt gctttcctcg tgtttcctga tcctgccttg ggtctgtagt catacttctg 2400 gaaattcctt ttgggtccaa gacgaggagg ttcctctaag atctcatggc cctgcttcct 2460 cccagtcccc tcacagggca ttttcttccc acaggtggaa aaggagggag ctactctcag 2520 gctgcgtgta agtgatgggg gtgggagtgt ggaggagctc acccacccca taattcctcc 2580 tgtcccacgt ctcctgcggg ctctgaccag gtcctgtttt tgttctactc caggcagcga 2640 cagtgcccag ggctctgatg tgtctctcac agcttga 2677 //